Patrick D. Lyden - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 

303 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Huang YX, Mahler S, Abedi A, Tyszka JM, Lo YT, Lyden PD, Russin J, Liu C, Yang C. Correlating stroke risk with non-invasive cerebrovascular perfusion dynamics using a portable speckle contrast optical spectroscopy laser device. Biomedical Optics Express. 15: 6083-6097. PMID 39421763 DOI: 10.1364/BOE.534796  0.405
2024 Monjazeb S, Chang HV, Lyden PD. Before, during, and after: An Argument for Safety and Improved Outcome of Thrombolysis in Acute Ischemic Stroke with Direct Oral Anticoagulant Treatment. Annals of Neurology. PMID 39258443 DOI: 10.1002/ana.27058  0.502
2024 Gillani SA, Ma X, Huang Y, Bains NK, Fakih R, Siddiq F, French BR, Gomez CR, Lyden PD, Qureshi AI. Effect of post thrombolytic intracerebral hemorrhage volume on 90-day outcomes in acute ischemic stroke patients. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 33: 107962. PMID 39191317 DOI: 10.1016/j.jstrokecerebrovasdis.2024.107962  0.493
2024 Huang YX, Mahler S, Abedi A, Tyszka JM, Lo YT, Lyden PD, Russin J, Liu C, Yang C. Correlating Stroke Risk with Non-Invasive Tracing of Brain Blood Dynamic via a Portable Speckle Contrast Optical Spectroscopy Laser Device. Arxiv. PMID 39108296  0.415
2024 Morais A, Imai T, Jin X, Locascio JJ, Boisserand L, Herman AL, Chauhan A, Lamb J, Nagarkatti K, Diniz MA, Kumskova M, Dhanesha N, Kamat PK, Badruzzaman Khan M, Dhandapani KM, ... ... Lyden PD, et al. Biological and Procedural Predictors of Outcome in the Stroke Preclinical Assessment Network (SPAN) Trial. Circulation Research. PMID 39034919 DOI: 10.1161/CIRCRESAHA.123.324139  0.457
2024 Xiao J, Poblete RA, Lerner A, Nguyen PL, Song JW, Sanossian N, Wilcox AG, Song SS, Lyden PD, Saver JL, Wasserman BA, Fan Z. MRI in the Evaluation of Cryptogenic Stroke and Embolic Stroke of Undetermined Source. Radiology. 311: e231934. PMID 38652031 DOI: 10.1148/radiol.231934  0.499
2024 Stockbridge MD, Kelly L, Newman-Norlund S, White B, Bourgeois M, Rothermel E, Fridriksson J, Lyden PD, Hillis AE. New Picture Stimuli for the NIH Stroke Scale: A Validation Study. Stroke. 55: 443-451. PMID 38252764 DOI: 10.1161/STROKEAHA.123.044384  0.456
2023 Samaniego EA, Boltze J, Lyden PD, Hill MD, Campbell BCV, Silva GS, Sheth KN, Fisher M, Hillis AE, Nguyen TN, Carone D, Favilla CG, Deljkich E, Albers GW, Heit JJ, et al. Priorities for Advancements in Neuroimaging in the Diagnostic Workup of Acute Stroke. Stroke. PMID 37942645 DOI: 10.1161/STROKEAHA.123.044985  0.454
2023 Wechsler LR, Adeoye O, Alemseged F, Bahr-Hosseini M, Deljkich E, Favilla C, Fisher M, Grotta J, Hill MD, Kamel H, Khatri P, Lyden P, Mirza M, Nguyen TN, Samaniego E, et al. Most Promising Approaches to Improve Stroke Outcomes: The Stroke Treatment Academic Industry Roundtable XII Workshop. Stroke. PMID 37886850 DOI: 10.1161/STROKEAHA.123.044279  0.48
2023 Lyden PD, Diniz MA, Bosetti F, Lamb J, Nagarkatti KA, Rogatko A, Kim S, Cabeen RP, Koenig JI, Akhter K, Arbab AS, Avery BD, Beatty HE, Bibic A, Cao S, et al. A multi-laboratory preclinical trial in rodents to assess treatment candidates for acute ischemic stroke. Science Translational Medicine. 15: eadg8656. PMID 37729432 DOI: 10.1126/scitranslmed.adg8656  0.359
2023 Broderick JP, Silva GS, Selim M, Kasner SE, Aziz Y, Sutherland J, Jauch EC, Adeoye OM, Hill MD, Mistry EA, Lyden PD, Mocco J, Smith EM, Hernandez-Jimenez M, Deljkich E, et al. Enhancing Enrollment in Acute Stroke Trials: Current State and Consensus Recommendations. Stroke. PMID 37694403 DOI: 10.1161/STROKEAHA.123.044149  0.467
2023 Schleicher R, Vorasayan P, McCabe M, Bevers MB, Davis TP, Griffin J, Hinduja A, Jadhav A, Lee JM, Sawyer RN, Zlokovic BV, Sheth K, Fedler JK, Lyden P, Kimberly WT. Analysis of Brain Edema in RHAPSODY. International Journal of Stroke : Official Journal of the International Stroke Society. 17474930231187268. PMID 37382409 DOI: 10.1177/17474930231187268  0.403
2023 Morais A, Locascio JJ, Sansing LH, Lamb J, Nagarkatti K, Imai T, van Leyen K, Aronowski J, Koenig JI, Bosetti F, Lyden P, Ayata C. Embracing Heterogeneity in The Multicenter Stroke Preclinical Assessment Network (SPAN) Trial. Stroke. 54: 620-631. PMID 36601951 DOI: 10.1161/STROKEAHA.122.040638  0.321
2022 Lyden P, Schwamm LH, Mohl SM. 2022 Update From the American Stroke Association and the Stroke Council. Stroke. 53: e383-e384. PMID 35877821 DOI: 10.1161/STROKEAHA.122.039161  0.467
2022 Steinberg A, Lyden PD, Davis AP. Bias in Stroke Evaluation: Rethinking the Cookie Theft Picture. Stroke. 101161STROKEAHA12103. PMID 35514285 DOI: 10.1161/STROKEAHA.121.038515  0.44
2022 Lyden PD, Bosetti F, Diniz MA, Rogatko A, Koenig JI, Lamb J, Nagarkatti KA, Cabeen RP, Hess DC, Kamat PK, Khan MB, Wood K, Dhandapani K, Arbab AS, Leira EC, et al. The Stroke Preclinical Assessment Network: Rationale, Design, Feasibility, and Stage 1 Results. Stroke. 101161STROKEAHA12103. PMID 35354299 DOI: 10.1161/STROKEAHA.121.038047  0.405
2022 Kam W, Holmes DN, Hernandez AF, Saver JL, Fonarow GC, Smith EE, Bhatt DL, Schwamm LH, Reeves MJ, Matsouaka RA, Khan YM, Unverdorben M, Birmingham MC, Lyden PD, Asimos AW, et al. Association of Recent Use of Non-Vitamin K Antagonist Oral Anticoagulants With Intracranial Hemorrhage Among Patients With Acute Ischemic Stroke Treated With Alteplase. Jama. PMID 35143601 DOI: 10.1001/jama.2022.0948  0.413
2021 de Jonge JC, van de Beek D, Lyden P, Brady MC, Bath PM, van der Worp HB. Temporal Profile of Pneumonia After Stroke. Stroke. STROKEAHA120032787. PMID 34517764 DOI: 10.1161/STROKEAHA.120.032787  0.437
2021 Lyden PD. Cerebroprotection for Acute Ischemic Stroke: Looking Ahead. Stroke. 52: 3033-3044. PMID 34289710 DOI: 10.1161/STROKEAHA.121.032241  0.342
2021 Padrick MM, Sangha N, Paletz L, Mirocha J, Figueroa S, Manoukian V, Schlick K, Lyden PD, Liebeskind DS, Chatfield FK, Tarpley JW, Burgos A, Tenser M, Gaffney D, Pech MA, et al. COVID-19 Impact on Acute Ischemic Stroke Treatment at 9 Comprehensive Stroke Centers across Los Angeles. Cerebrovascular Diseases (Basel, Switzerland). 1-8. PMID 34175851 DOI: 10.1159/000516908  0.474
2021 Xiao J, Song SS, Schlick KH, Xia S, Jiang T, Han T, Jackson RJ, Diniz MA, Dumitrascu OM, Maya MM, Lyden PD, Li D, Yang Q, Fan Z. Disparate trends of atherosclerotic plaque evolution in stroke patients under 18-month follow-up: a 3D whole-brain magnetic resonance vessel wall imaging study. The Neuroradiology Journal. 19714009211026920. PMID 34159814 DOI: 10.1177/19714009211026920  0.314
2021 Lyden PD, Pryor KE, Minigh J, Davis TP, Griffin JH, Levy H, Zlokovic BV. Stroke Treatment With PAR-1 Agents to Decrease Hemorrhagic Transformation. Frontiers in Neurology. 12: 593582. PMID 33790846 DOI: 10.3389/fneur.2021.593582  0.465
2021 Xiao J, Padrick MM, Jiang T, Xia S, Wu F, Guo Y, Gonzalez NR, Li S, Schlick KH, Dumitrascu OM, Maya MM, Diniz MA, Song SS, Lyden PD, Li D, et al. Acute ischemic stroke versus transient ischemic attack: Differential plaque morphological features in symptomatic intracranial atherosclerotic lesions. Atherosclerosis. 319: 72-78. PMID 33486353 DOI: 10.1016/j.atherosclerosis.2021.01.002  0.449
2020 Fernandez-Ferro J, Schwamm LH, Lyden PD, Lees KR. Amendment on the article "Missing outcome data management in acute stroke trials testing iv thrombolytics: Is there risk of bias?" European Stroke Journal. 5: 453-454. PMID 33598566 DOI: 10.1177/2396987320957188  0.383
2020 Chamorro Á, Lo EH, Renú A, van Leyden K, Lyden PD. The future of neuroprotection in stroke. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 33148815 DOI: 10.1136/jnnp-2020-324283  0.353
2020 Lyden PD. Stroke, Research and Science in the Time of COVID. Stroke. 51: 2613-2614. PMID 32755344 DOI: 10.1161/Strokeaha.120.031354  0.49
2020 Dumitrascu OM, Volod O, Bose S, Wang Y, Biousse V, Lyden PD. Acute ophthalmic artery occlusion in a COVID-19 patient on apixaban. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 29: 104982. PMID 32689586 DOI: 10.1016/J.Jstrokecerebrovasdis.2020.104982  0.412
2020 Fernandez-Ferro J, Schwamm LH, Descalzo MA, MacIsaac R, Lyden PD, Lees KR. Missing outcome data management in acute stroke trials testing iv thrombolytics. Is there risk of bias? European Stroke Journal. 5: 148-154. PMID 32637648 DOI: 10.1177/2396987320905457  0.397
2020 Mukherjee P, Lyden P, Fernández JA, Davis TP, Pryor KE, Zlokovic BV, Griffin JH. 3K3A-Activated Protein C Variant Does Not Interfere With the Plasma Clot Lysis Activity of Tenecteplase. Stroke. 51: 2236-2239. PMID 32568648 DOI: 10.1161/Strokeaha.120.028793  0.527
2020 Lyden P. Selective cerebral cooling for acute ischemic stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 40: 1365-1367. PMID 32423332 DOI: 10.1177/0271678X20925026  0.564
2020 Lyden PD. Measuring Outcome After Stroke: More Lessons Learned Again. Stroke. STROKEAHA119028214. PMID 32102628 DOI: 10.1161/Strokeaha.119.028214  0.457
2020 Melmed KR, Schlick KH, Rinsky B, Dumitrascu OM, Volod O, Nezhad M, Padrick MM, Runyan C, Arabia FA, Moriguchi JD, Lyden PD, Song SS. Assessing Cerebrovascular Hemodynamics Using Transcranial Doppler in Patients with Mechanical Circulatory Support Devices. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. PMID 32037621 DOI: 10.1111/Jon.12694  0.377
2020 Anderson A, Klein J, White B, Bourgeois M, Leonard A, Pacino A, Hill J, Lyden P. Training and Certifying Users of the National Institutes of Health Stroke Scale. Stroke. STROKEAHA119027234. PMID 31986988 DOI: 10.1161/Strokeaha.119.027234  0.438
2020 Fernandez-Ferro J, Schwamm LH, Lyden PD, Lees KR. Amendment on the article “Missing outcome data management in acute stroke trials testing iv thrombolytics: Is there risk of bias?” European Stroke Journal. 5: 453-454. DOI: 10.1177/2396987320957188  0.384
2019 Rajput PS, Lamb J, Kothari S, Pereira B, Soetkamp D, Wang Y, Tang J, Van Eyk JE, Mullins ES, Lyden PD. Neuron-generated thrombin induces a protective astrocyte response via protease activated receptors. Glia. PMID 31453648 DOI: 10.1002/Glia.23714  0.309
2019 Lyden PD. Thrombolytic Therapy for Acute Ischemic Stroke. Stroke. STROKEAHA119025699. PMID 31327316 DOI: 10.1161/Strokeaha.119.025699  0.551
2019 Kurz MC, Lyden P, Dae M, Noc M. Studies Targeting Stroke and Acute Myocardial Infarction Therapeutic Hypothermia and Temperature Management. 9: 8-12. PMID 30614768 DOI: 10.1089/Ther.2018.29054.Mck  0.501
2019 Basto FM, Lyden P. Hypothermia in acute ischemic stroke therapy. Handbook of Clinical Neurology. 157: 823-837. PMID 30459043 DOI: 10.1016/B978-0-444-64074-1.00051-3  0.502
2019 Lyden P, Ernstrom K, Raman R. Determinants of Pneumonia Risk During Endovascular Hypothermia. Therapeutic Hypothermia and Temperature Management. 3: 24-27. PMID 23667781 DOI: 10.1089/Ther.2012.0021  0.37
2018 Lyden PD, Lamb J, Kothari S, Toossi S, Boitano P, Rajput PS. Differential effects of hypothermia on neurovascular unit determine protective or toxic results: Toward optimized therapeutic hypothermia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X18814614. PMID 30461327 DOI: 10.1177/0271678X18814614  0.423
2018 Lyden P, Pryor KE, Coffey CS, Cudkowicz M, Conwit R, Jadhav A, Sawyer RN, Claassen J, Adeoye O, Song S, Hannon P, Rost NS, Hinduja A, Torbey M, Lee JM, et al. Final Results of the RHAPSODY trial: A multi-center, Phase 2 trial using a continual reassessment method to determine the safety and tolerability of 3K3A-APC, a Recombinant Variant of Human Activated Protein C, in combination with tissue plasminogen activator, mechanical thrombectomy or both in moderate to severe acute ischemic stroke. Annals of Neurology. PMID 30450637 DOI: 10.1002/Ana.25383  0.488
2018 Al-Shahi Salman R, Frantzias J, Lee RJ, Lyden PD, Battey TWK, Ayres AM, Goldstein JN, Mayer SA, Steiner T, Wang X, Arima H, Hasegawa H, Oishi M, Godoy DA, Masotti L, et al. Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data. The Lancet. Neurology. PMID 30120039 DOI: 10.1016/S1474-4422(18)30253-9  0.313
2018 Lyden P. Justin A. Zivin, MD, PhD: August 17, 1946-February 17, 2018. Stroke. 49: 1051-1052. PMID 29669869 DOI: 10.1161/Strokeaha.118.021264  0.565
2018 Yu W, Kavi T, Majic T, Alva K, Moheet A, Lyden P, Schievink W, Lekovic G, Alexander M. Treatment Modality and Quality Benchmarks of Aneurysmal Subarachnoid Hemorrhage at a Comprehensive Stroke Center. Frontiers in Neurology. 9: 152. PMID 29599745 DOI: 10.3389/Fneur.2018.00152  0.559
2018 Dumitrascu OM, Demaerschalk BM, Valencia Sanchez C, Almader-Douglas D, O'Carroll CB, Aguilar MI, Lyden PD, Kumar G. Retinal Microvascular Abnormalities as Surrogate Markers of Cerebrovascular Ischemic Disease: A Meta-Analysis. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. PMID 29571764 DOI: 10.1016/J.Jstrokecerebrovasdis.2018.02.041  0.357
2018 Lyden PD. When less is more (brain)-Comment on "Rivaroxaban plasma levels in acute ischemic stroke and intracerebral hemorrhage". Annals of Neurology. PMID 29394506 DOI: 10.1002/Ana.25163  0.525
2018 Yogendrakumar V, Smith EE, Demchuk AM, Aviv RI, Rodriguez-Luna D, Molina CA, Silva Blas Y, Dzialowski I, Kobayashi A, Boulanger JM, Lum C, Gubitz G, Padma V, Roy J, Kase CS, ... ... Lyden P, et al. Lack of Early Improvement Predicts Poor Outcome Following Acute Intracerebral Hemorrhage. Critical Care Medicine. PMID 29303797 DOI: 10.1097/Ccm.0000000000002962  0.346
2018 Gonzalez NR, Barnard Z, Jiang H, Kurth F, Lyden PD, Schlick KH, Song S, Liou R, Alexander M, Schievink W, Saver JL. Abstract WP127: Effects of EDAS Revascularization and Intensive Medical Management on the Cognitive Function of Patients With Intracranial Atherosclerosis Stroke. 49. DOI: 10.1161/Str.49.Suppl_1.Wp127  0.349
2018 Lapchak PA, Boitano PD, Schubert D, Lyden PD. Abstract TP260: A Novel Neurogenic-Stem Cell Stimulating Curcumin Analog to Treat Acute Ischemic Stroke Stroke. 49. DOI: 10.1161/Str.49.Suppl_1.Tp260  0.462
2018 Flaherty K, De Georgia MA, Hemmen TM, Kollmar R, Krieger DW, Lyden P, Petersson J, Piironen K, Poli S, Van de Worp B, Bath PM. Abstract TMP13: Individual Patient Data Meta-analysis of Hypothermia for Acute Ischaemic Stroke Stroke. 49. DOI: 10.1161/Str.49.Suppl_1.Tmp13  0.548
2017 Hacke W, Lyden P, Emberson J, Baigent C, Blackwell L, Albers G, Bluhmki E, Brott T, Cohen G, Davis SM, Donnan GA, Grotta JC, Howard G, Kaste M, Koga M, et al. Effects of alteplase for acute stroke according to criteria defining the European Union and United States marketing authorizations: Individual-patient-data meta-analysis of randomized trials. International Journal of Stroke : Official Journal of the International Stroke Society. 1747493017744464. PMID 29171359 DOI: 10.1177/1747493017744464  0.44
2017 Bosetti F, Koenig JI, Ayata C, Back SA, Becker K, Broderick JP, Carmichael ST, Cho S, Cipolla MJ, Corbett D, Corriveau RA, Cramer SC, Ferguson AR, Finklestein SP, Ford BD, ... ... Lyden PD, et al. Translational Stroke Research: Vision and Opportunities. Stroke. PMID 28751554 DOI: 10.1161/Strokeaha.117.017112  0.6
2017 Grotta JC, Lyden P, Brott T. Rethinking Training and Distribution of Vascular Neurology Interventionists in the Era of Thrombectomy. Stroke. PMID 28706124 DOI: 10.1161/Strokeaha.116.016416  0.363
2017 Li Y, Shen XZ, Li L, Zhao TV, Bernstein KE, Johnson AK, Lyden P, Fang J, Shi P. Brain Transforming Growth Factor-β Resists Hypertension Via Regulating Microglial Activation. Stroke. PMID 28698257 DOI: 10.1161/Strokeaha.117.017370  0.321
2017 Lahiri S, Nezhad M, Schlick KH, Rinsky B, Rosengart A, Mayer SA, Lyden PD. Paradoxical cerebrovascular hemodynamic changes with nicardipine. Journal of Neurosurgery. 1-5. PMID 28430036 DOI: 10.3171/2016.11.Jns161992  0.417
2017 Lundbye J, Lyden PD, Polderman KH, Schwab S. Clinical Studies Targeting Stroke and Ischemic Insults. Therapeutic Hypothermia and Temperature Management. 7: 12-15. PMID 28253089 DOI: 10.1089/Ther.2016.29022.Jjl  0.549
2017 Lundbye J, Lyden PD, Polderman KH, Schwab S. Clinical Studies Targeting Stroke and Ischemic Insults. Therapeutic Hypothermia and Temperature Management. PMID 28106522 DOI: 10.1089/ther.2016.29022.jjl.rev  0.462
2017 Lyden P. Using the National Institutes of Health Stroke Scale: A Cautionary Tale. Stroke. 48: 513-519. PMID 28077454 DOI: 10.1161/Strokeaha.116.015434  0.571
2017 Simons SM, Rosengart A, Schlick K, Torbati S, Lyden PD, Internationals O. Sildenafil Associated Threatened Ischemic Stroke Reversed with Alteplase International Journal of Neurology. 4: 0-0. DOI: 10.15436/2377-1348.17.1371  0.564
2016 Melmed KR, Lyden PD. Meta-Analysis of Pre-Clinical Trials of Therapeutic Hypothermia for Intracerebral Hemorrhage. Therapeutic Hypothermia and Temperature Management. PMID 27906602 DOI: 10.1089/Ther.2016.0033  0.424
2016 Lyden P, Hemmen T, Grotta J, Rapp K, Ernstrom K, Rzesiewicz T, Parker S, Concha M, Hussain S, Agarwal S, Meyer B, Jurf J, Altafullah I, Raman R. Results of the ICTuS 2 Trial (Intravascular Cooling in the Treatment of Stroke 2). Stroke; a Journal of Cerebral Circulation. PMID 27834742 DOI: 10.1161/Strokeaha.116.014200  0.588
2016 Lyden P, Weymer S, Coffey C, Cudkowicz M, Berg S, O'Brien S, Fisher M, Haley EC, Khatri P, Saver J, Levine S, Levy H, Rymer M, Wechsler L, Jadhav A, et al. Selecting Patients for Intra-Arterial Therapy in the Context of a Clinical Trial for Neuroprotection. Stroke; a Journal of Cerebral Circulation. PMID 27803392 DOI: 10.1161/Strokeaha.116.013881  0.473
2016 Lahiri S, Schlick K, Kavi T, Song S, Moheet A, Yusufali T, Rosengart A, Alexander MJ, Lyden PD. Optimizing Outcomes for Mechanically Ventilated Patients in an Era of Endovascular Acute Ischemic Stroke Therapy. Journal of Intensive Care Medicine. PMID 27543141 DOI: 10.1177/0885066616663168  0.46
2016 Lees KR, Emberson J, Blackwell L, Bluhmki E, Davis SM, Donnan GA, Grotta JC, Kaste M, von Kummer R, Lansberg MG, Lindley RI, Lyden P, Murray GD, Sandercock PA, Toni D, et al. Effects of Alteplase for Acute Stroke on the Distribution of Functional Outcomes: A Pooled Analysis of 9 Trials. Stroke; a Journal of Cerebral Circulation. PMID 27507856 DOI: 10.1161/Strokeaha.116.013644  0.531
2016 Whiteley WN, Emberson J, Lees KR, Blackwell L, Albers G, Bluhmki E, Brott T, Cohen G, Davis S, Donnan G, Grotta J, Howard G, Kaste M, Koga M, von Kummer R, ... ... Lyden P, et al. Risk of intracerebral haemorrhage with alteplase after acute ischaemic stroke: a secondary analysis of an individual patient data meta-analysis. The Lancet. Neurology. PMID 27289487 DOI: 10.1016/S1474-4422(16)30076-X  0.516
2016 Griffin JH, Fernández JA, Lyden PD, Zlokovic BV. Activated protein C promotes neuroprotection: mechanisms and translation to the clinic. Thrombosis Research. 141: S62-S64. PMID 27207428 DOI: 10.1016/S0049-3848(16)30368-1  0.363
2016 Lamb JA, Rajput PS, Lyden PD. Novel method for inducing rapid, controllable therapeutic hypothermia in rats using a perivascular implanted closed-loop cooling circuit. Journal of Neuroscience Methods. 267: 55-61. PMID 27090948 DOI: 10.1016/J.Jneumeth.2016.04.011  0.415
2016 Dumitrascu OM, Lamb J, Lyden PD. Still cooling after all these years: Meta-analysis of pre-clinical trials of therapeutic hypothermia for acute ischemic stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 27089911 DOI: 10.1177/0271678X16645112  0.526
2016 Kurz M, Lundbye J, Lyden PD. Clinical Studies Targeting Stroke and In-Hospital Cardiac Arrest. Therapeutic Hypothermia and Temperature Management. PMID 26799665 DOI: 10.1089/Ther.2016.29008.Mjk  0.446
2016 Hesse K, MacIsaac RL, Abdul-Rahim AH, Lyden PD, Bluhmki E, Lees KR. Online Tool to Improve Stratification of Adverse Events in Stroke Clinical Trials. Stroke; a Journal of Cerebral Circulation. PMID 26742798 DOI: 10.1161/Strokeaha.115.011930  0.554
2015 Ali M, Lyden P, Brady M. Aphasia and Dysarthria in Acute Stroke: Recovery and Functional Outcome. International Journal of Stroke : Official Journal of the International Stroke Society. 10: 400-406. PMID 28742466 DOI: 10.1111/Ijs.12067  0.536
2015 Lahiri S, Nuño M, Lyden PD. Letter by Lahiri et al Regarding Article, "Endovascular Thrombectomy for Anterior Circulation Stroke: Systematic Review and Meta-Analysis". Stroke; a Journal of Cerebral Circulation. PMID 26534970 DOI: 10.1161/Strokeaha.115.011677  0.48
2015 Hussein HM, Abdel Moneim A, Emara T, Abd-Elhamid YA, Salem HH, Abd-Allah F, Farrag MA, Tork MA, Shalash AS, Ezz El Dein KH, Osman G, Georgy SS, Ghali PG, Lyden PD, Moustafa RR. Arabic cross cultural adaptation and validation of the National Institutes of Health Stroke Scale. Journal of the Neurological Sciences. 357: 152-6. PMID 26210056 DOI: 10.1016/J.Jns.2015.07.022  0.514
2015 Lyden P. Why don't more patients receive intravenous rt-PA for acute stroke? Expert Review of Neurotherapeutics. 15: 571-4. PMID 25938622 DOI: 10.1586/14737175.2015.1041510  0.485
2015 Lyden P. Why don't more patients receive intravenous rt-PA for acute stroke? Expert Review of Neurotherapeutics. 15: 571-4. PMID 25938622 DOI: 10.1586/14737175.2015.1041510  0.485
2015 Emberson J, Lees KR, Lyden P, Baigent C, Sandercock P, Hacke W. Thrombolysis in acute stroke--authors' reply Lancet. 385: 1396. PMID 25890422 DOI: 10.1016/S0140-6736(15)60718-8  0.555
2015 Lyden PD, Rincon F, Staykov D, Lyden PD. Clinical studies targeting stroke. Therapeutic Hypothermia and Temperature Management. 5: 4-8. PMID 25692220 DOI: 10.1089/Ther.2015.1501  0.52
2015 Bai J, Lyden PD. Revisiting cerebral postischemic reperfusion injury: new insights in understanding reperfusion failure, hemorrhage, and edema. International Journal of Stroke : Official Journal of the International Stroke Society. 10: 143-52. PMID 25598025 DOI: 10.1111/Ijs.12434  0.425
2015 Abdul-Rahim AH, Fulton RL, Frank B, Mcmurray JJV, Lees KR, Alexandrov AV, Bath PW, Bluhmki E, Claesson L, Curram J, Davis SM, Donnan G, Diener HC, Fisher M, Gregson B, ... ... Lyden P, et al. Associations of chronic heart failure with outcome in acute ischaemic stroke patients who received systemic thrombolysis: Analysis from VISTA European Journal of Neurology. 22: 163-169. PMID 25370204 DOI: 10.1111/ene.12548  0.392
2015 Abdul-Rahim AH, Fulton RL, Frank B, Tatlisumak T, Paciaroni M, Caso V, Diener HC, Lees KR, Alexandrov AV, Bath PW, Bluhmki E, Claesson L, Curram J, Davis SM, Donnan G, ... ... Lyden P, et al. Association of improved outcome in acute ischaemic stroke patients with atrial fibrillation who receive early antithrombotic therapy: Analysis from VISTA European Journal of Neurology. 22: 1048-1055. PMID 25319957 DOI: 10.1111/ene.12577  0.448
2015 Drazin D, Rosner J, Nuño M, Alexander MJ, Schievink WI, Palestrant D, Lyden PD, Miller C. Type of admission is associated with outcome of spontaneous subarachnoid hemorrhage. International Journal of Stroke : Official Journal of the International Stroke Society. 10: 529-33. PMID 23489935 DOI: 10.1111/Ijs.12005  0.492
2015 Beare R, Chen J, Phan TG, Lees KR, Ali M, Alexandrov A, Bath PM, Bluhmki E, Bornstein N, Claesson L, Davis SM, Donnan G, Diener HC, Fisher M, Ginsberg M, ... ... Lyden P, et al. Googling Stroke ASPECTS to determine disability: Exploratory analysis from vista-acute collaboration Plos One. 10. DOI: 10.1371/journal.pone.0125687  0.455
2015 Abdul-Rahim AH, Fulton RL, Sucharew H, Kleindorfer D, Khatri P, Broderick JP, Lees KR, Alexandrov A, Bath PM, Bluhmki E, Bornstein N, Claesson L, Curram J, Davis SM, Donnan G, ... ... Lyden P, et al. National institutes of health stroke scale item profiles as predictor of patient outcome: External validation on independent trial data Stroke. 46: 395-400. DOI: 10.1161/STROKEAHA.114.006837  0.367
2015 Whiteley WN, Emberson J, Lees KR, Lyden P, Toni D, Toyoda K, Wahlgren N, Baigent C, SP, Wardlaw J, CS. The effect of delay, age, and stroke severity on the risk of intracranial hemorrhage after intravenous alteplase for acute stroke: An individual patient data meta-analysis International Journal of Stroke. 10: 21-21. DOI: 10.1111/Ijs.12634_5  0.562
2015 Ali M, Lyden P, Brady M. Aphasia and dysarthria in acute stroke: Recovery and functional outcome International Journal of Stroke. 10: 400-406. DOI: 10.1111/ijs.12067  0.437
2015 Lyden PD. Thrombolytic therapy for acute stroke and the test of time Thrombolytic Therapy For Acute Stroke, Third Edition. 165-180. DOI: 10.1007/978-3-319-07575-4_9  0.412
2015 Levine SR, Haley EC, Lyden PD. Pilot and preliminary studies of thrombolytic therapy for stroke Thrombolytic Therapy For Acute Stroke, Third Edition. 81-94. DOI: 10.1007/978-3-319-07575-4_4  0.436
2015 Marler J, Lyden PD. The rt-PA for acute stroke protocol Thrombolytic Therapy For Acute Stroke, Third Edition. 271-284. DOI: 10.1007/978-3-319-07575-4_14  0.445
2014 Rajput PS, Lyden PD, Chen B, Lamb JA, Pereira B, Lamb A, Zhao L, Lei IF, Bai J. Protease activated receptor-1 mediates cytotoxicity during ischemia using in vivo and in vitro models. Neuroscience. 281: 229-240. PMID 25261684 DOI: 10.1016/J.Neuroscience.2014.09.038  0.505
2014 Emberson J, Lees KR, Lyden P, Blackwell L, Albers G, Bluhmki E, Brott T, Cohen G, Davis S, Donnan G, Grotta J, Howard G, Kaste M, Koga M, von Kummer R, et al. Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials. Lancet (London, England). 384: 1929-35. PMID 25106063 DOI: 10.1016/S0140-6736(14)60584-5  0.592
2014 Schwab S, Lyden P, Kollmar R. Developing clinical trials in stroke. Therapeutic Hypothermia and Temperature Management. 1: 175-8. PMID 24717082 DOI: 10.1089/Ther.2011.1510  0.521
2014 Yeatts SD, Martin RH, Coffey CS, Lyden PD, Foster LD, Woolson RF, Broderick JP, Di Tullio MR, Jungreis CA, Palesch YY. Challenges of decision making regarding futility in a randomized trial: the Interventional Management of Stroke III experience. Stroke; a Journal of Cerebral Circulation. 45: 1408-14. PMID 24699059 DOI: 10.1161/Strokeaha.113.003925  0.477
2014 Lyden P, Pereira B, Chen B, Zhao L, Lamb J, Lei IF, Rajput P. Direct thrombin inhibitor argatroban reduces stroke damage in 2 different models Stroke. 45: 896-899. PMID 24473182 DOI: 10.1161/Strokeaha.113.004488  0.478
2014 Lyden PD, Hemmen TM, Grotta J, Rapp K, Raman R. Endovascular therapeutic hypothermia for acute ischemic stroke: ICTuS 2/3 protocol. International Journal of Stroke : Official Journal of the International Stroke Society. 9: 117-25. PMID 24206528 DOI: 10.1111/Ijs.12151  0.567
2014 Goldie FC, Fulton RL, Frank B, Lees KR, Alexandrov A, Bath PW, Bluhmki E, Claesson L, Curram J, Davis SM, Donnan G, Diener HC, Fisher M, Gregson B, Grotta J, ... ... Lyden P, et al. Interdependence of stroke outcome scales: Reliable estimates from the Virtual International Stroke Trials Archive (VISTA) International Journal of Stroke. 9: 328-332. PMID 24206445 DOI: 10.1111/ijs.12178  0.433
2014 Frank B, Fulton RL, Lees KR, Sanders RD, Alexandrov A, Bath PW, Bluhmki E, Bornstein N, Claesson L, Curram J, Davis SM, Donnan G, Diener HC, Fisher M, Gregson B, ... ... Lyden P, et al. Impact of benzodiazepines on functional outcome and occurrence of pneumonia in stroke: Evidence from VISTA International Journal of Stroke. 9: 890-894. PMID 24148353 DOI: 10.1111/ijs.12148  0.458
2014 Spokoyny I, Raman R, Ernstrom K, Demaerschalk BM, Lyden PD, Hemmen TM, Guzik AK, Chen JY, Meyer BC. Pooled assessment of computed tomography interpretation by vascular neurologists in the STRokE DOC telestroke network. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 23: 511-5. PMID 23697761 DOI: 10.1016/J.Jstrokecerebrovasdis.2013.04.023  0.527
2014 Ali M, Bath PM, Lyden PD, Bernhardt J, Brady M. Representation of people with aphasia in randomized controlled trials of acute stroke interventions. International Journal of Stroke : Official Journal of the International Stroke Society. 9: 174-82. PMID 23506193 DOI: 10.1111/Ijs.12043  0.553
2014 Huisa BN, Neil WP, Schrader R, Maya M, Pereira B, Bruce NT, Lyden PD. Clinical use of computed tomographic perfusion for the diagnosis and prediction of lesion growth in acute ischemic stroke. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 23: 114-22. PMID 23253533 DOI: 10.1016/J.Jstrokecerebrovasdis.2012.10.020  0.448
2013 Lyden MP, Colbourne PF, Lyden P, Schwab S. Preclinical and clinical studies targeting therapeutic hypothermia in cerebral ischemia and stroke. Therapeutic Hypothermia and Temperature Management. 3: 3-6. PMID 24837632 DOI: 10.1089/Ther.2013.1500  0.534
2013 Lyden PD. Mild hypothermia reduces tissue plasminogen activator-related hemorrhage and blood brain barrier disruption after experimental stroke: editorial commentary on tang et Al., 2013. Therapeutic Hypothermia and Temperature Management. 3: 171-2. PMID 24834949 DOI: 10.1089/Ther.2013.0014  0.432
2013 Lyden MP, Gupta PR, Kollmar R, Lyden PD. Preclinical and clinical studies targeting stroke. Therapeutic Hypothermia and Temperature Management. 3: 114-9. PMID 24834840 DOI: 10.1089/Ther.2013.1512  0.519
2013 Lyden P, Levy H, Weymer S, Pryor K, Kramer W, Griffin JH, Davis TP, Zlokovic B. Phase 1 safety, tolerability and pharmacokinetics of 3K3A-APC in healthy adult volunteers. Current Pharmaceutical Design. 19: 7479-85. PMID 24372304 DOI: 10.2174/1381612819666131230131454  0.325
2013 Saver JL, Jovin TG, Smith WS, Albers GW, Baron JC, Boltze J, Broderick JP, Davis LA, Demchuk AM, DeSena S, Fiehler J, Gorelick PB, Hacke W, Holt B, Jahan R, ... ... Lyden P, et al. Stroke treatment academic industry roundtable: research priorities in the assessment of neurothrombectomy devices. Stroke; a Journal of Cerebral Circulation. 44: 3596-601. PMID 24193797 DOI: 10.1161/Strokeaha.113.002769  0.539
2013 Wang Y, Zhao Z, Chow N, Rajput PS, Griffin JH, Lyden PD, Zlokovic BV. Activated protein C analog protects from ischemic stroke and extends the therapeutic window of tissue-type plasminogen activator in aged female mice and hypertensive rats. Stroke; a Journal of Cerebral Circulation. 44: 3529-36. PMID 24159062 DOI: 10.1161/Strokeaha.113.003350  0.534
2013 Akbari S, Lyden PD, Kamali M, Fahimi MA. Correlations among impairment, daily activities and thinking operations after stroke. Neurorehabilitation. 33: 153-60. PMID 23949044 DOI: 10.3233/Nre-130940  0.468
2013 Wintermark M, Albers GW, Broderick JP, Demchuk AM, Fiebach JB, Fiehler J, Grotta JC, Houser G, Jovin TG, Lees KR, Lev MH, Liebeskind DS, Luby M, Muir KW, Parsons MW, ... ... Lyden P, et al. Acute Stroke Imaging Research Roadmap II. Stroke; a Journal of Cerebral Circulation. 44: 2628-39. PMID 23860298 DOI: 10.1161/Strokeaha.113.002015  0.523
2013 Emberson J, Lees KR, Howard G, Bluhmki E, Tilley B, Albers G, Baigent C, Blackwell L, Davis S, Donnan G, Grotta J, Hacke W, Kaste M, von Kummer R, Lansberg M, ... ... Lyden P, et al. Details of a prospective protocol for a collaborative meta-analysis of individual participant data from all randomized trials of intravenous rt-PA vs. control: Statistical analysis plan for the Stroke Thrombolysis Trialists' Collaborative meta-analysis International Journal of Stroke. 8: 278-283. PMID 23639145 DOI: 10.1111/Ijs.12040  0.536
2013 Lyden PD. Hemorrhagic transformation during thrombolytic therapy and reperfusion: effects of age, blood pressure, and matrix metalloproteinases. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 22: 532-8. PMID 23453556 DOI: 10.1016/J.Jstrokecerebrovasdis.2013.02.001  0.359
2013 Frank B, Grotta JC, Alexandrov AV, Bluhmki E, Lyden P, Meretoja A, Mishra NK, Shuaib A, Wahlgren NG, Weimar C, Lees KR. Thrombolysis in stroke despite contraindications or warnings? Stroke. 44: 727-733. PMID 23391774 DOI: 10.1161/Strokeaha.112.674622  0.579
2013 Van Winkle JA, Chen B, Lei IF, Pereira B, Rajput PS, Lyden PD. Concurrent middle cerebral artery occlusion and intra-arterial drug infusion via ipsilateral common carotid artery catheter in the rat. Journal of Neuroscience Methods. 213: 63-9. PMID 23261656 DOI: 10.1016/J.Jneumeth.2012.12.004  0.466
2013 Shih AY, Blinder P, Tsai PS, Friedman B, Stanley G, Lyden PD, Kleinfeld D. The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit. Nature Neuroscience. 16: 55-63. PMID 23242312 DOI: 10.1038/Nn.3278  0.372
2013 Chen B, Van Winkle JA, Lyden PD, Brown JH, Purcell NH. PHLPP1 gene deletion protects the brain from ischemic injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 196-204. PMID 23072745 DOI: 10.1038/Jcbfm.2012.150  0.408
2013 Rincon F, Lyden P, Mayer SA. Relationship between temperature, hematoma growth, and functional outcome after intracerebral hemorrhage. Neurocritical Care. 18: 45-53. PMID 23001769 DOI: 10.1007/S12028-012-9779-9  0.325
2013 Ali M, Hazelton C, Lyden P, Pollock A, Brady M. Recovery from poststroke visual impairment: evidence from a clinical trials resource. Neurorehabilitation and Neural Repair. 27: 133-41. PMID 22961263 DOI: 10.1177/1545968312454683  0.412
2012 Lyden P, Lapchak P. Sisyphus and translational stroke research Science Translational Medicine. 4. PMID 23076354 DOI: 10.1126/Scitranslmed.3005083  0.499
2012 Song SS, Lyden PD. Overview of therapeutic hypothermia. Current Treatment Options in Neurology. 14: 541-8. PMID 23007950 DOI: 10.1007/S11940-012-0201-X  0.413
2012 Nuño M, Patil CG, Lyden P, Drazin D. The effect of transfer and hospital volume in subarachnoid hemorrhage patients. Neurocritical Care. 17: 312-23. PMID 22843190 DOI: 10.1007/S12028-012-9740-Y  0.304
2012 Chen B, Friedman B, Whitney MA, Winkle JA, Lei IF, Olson ES, Cheng Q, Pereira B, Zhao L, Tsien RY, Lyden PD. Thrombin activity associated with neuronal damage during acute focal ischemia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 7622-31. PMID 22649241 DOI: 10.1523/Jneurosci.0369-12.2012  0.459
2012 Lyden PD. In anticipation of International Stroke Trial-3 (IST-3). Stroke; a Journal of Cerebral Circulation. 43: 1691-4. PMID 22556196 DOI: 10.1161/Strokeaha.112.656876  0.51
2012 Lyden PD. Stroke: Haemorrhage risk after thrombolysis--the SEDAN score. Nature Reviews. Neurology. 8: 246-7. PMID 22508227 DOI: 10.1038/Nrneurol.2012.66  0.448
2012 Lyden P, Ernstrom K, Cruz-Flores S, Gomes J, Grotta J, Mullin A, Rapp K, Raman R, Wijman C, Hemmen T. Determinants of effective cooling during endovascular hypothermia. Neurocritical Care. 16: 413-20. PMID 22466971 DOI: 10.1007/S12028-012-9688-Y  0.318
2012 Lyden P. Editorial on "A simple, assumption-free, and clinically interpretable approach for analysis of modified rankin outcomes" Stroke. 43: 621-622. PMID 22343651 DOI: 10.1161/Strokeaha.111.641019  0.555
2012 Barreto AD, Alexandrov AV, Lyden P, Lee J, Martin-Schild S, Shen L, Wu TC, Sisson A, Pandurengan R, Chen Z, Rahbar MH, Balucani C, Barlinn K, Sugg RM, Garami Z, et al. The argatroban and tissue-type plasminogen activator stroke study: final results of a pilot safety study. Stroke; a Journal of Cerebral Circulation. 43: 770-5. PMID 22223235 DOI: 10.1161/Strokeaha.111.625574  0.473
2012 Kerr DM, Fulton RL, Higgins P, Bath PM, Shuaib A, Lyden P, Lees KR. Response of blood pressure and blood glucose to treatment with recombinant tissue-type plasminogen activator in acute ischemic stroke: evidence from the virtual international stroke trials archive. Stroke; a Journal of Cerebral Circulation. 43: 399-404. PMID 22075999 DOI: 10.1161/Strokeaha.111.627059  0.507
2012 Hemmen T, Rapp K, Raman R, Concha M, Brössner G, Schmutzhard E, Tafreshi G, Misra V, Cruz-Flores S, Kollmar R, Brown D, Altafullah I, Michel P, Alexandrov A, Smith C, ... ... Lyden PD, et al. Phase 2/3 study of intravenous thrombolysis and hypothermia for acute treatment of ischemic stroke (ICTuS 2/3) Critical Care. 16. DOI: 10.1186/Cc11271  0.543
2011 Akbari S, Ashayeri H, Fahimi MA, Kamali M, Lyden PD. The correlation of independency in activities of daily living performance with cognitive status and the intensity of neurological impairment in right-handed stroke patients. Neurorehabilitation. 29: 311-6. PMID 22142765 DOI: 10.3233/Nre-2011-0707  0.522
2011 Lyden P. Tenecteplase for acute ischemic stroke International Journal of Stroke. 6: 509-510. PMID 22111795 DOI: 10.1111/J.1747-4949.2011.00695.X  0.567
2011 Tu HT, Campbell BC, Churilov L, Kalman JM, Lees KR, Lyden PD, Shuaib A, Donnan GA, Davis SM. Frequent early cardiac complications contribute to worse stroke outcome in atrial fibrillation. Cerebrovascular Diseases (Basel, Switzerland). 32: 454-60. PMID 22005390 DOI: 10.1159/000332028  0.51
2011 Lyden P. The future of basic science research and stroke: Hubris and translational stroke research International Journal of Stroke. 6: 412-413. PMID 21951405 DOI: 10.1111/J.1747-4949.2011.00657.X  0.507
2011 Lyden PD. Advanced brain imaging studies should not be performed in patients with suspected stroke presenting within 4.5 hours of symptom onset. Stroke; a Journal of Cerebral Circulation. 42: 2668-9. PMID 21817141 DOI: 10.1161/Strokeaha.111.621789  0.477
2011 Lees JS, Mishra NK, Saini M, Lyden PD, Shuaib A. Low body temperature does not compromise the treatment effect of alteplase. Stroke; a Journal of Cerebral Circulation. 42: 2618-21. PMID 21757664 DOI: 10.1161/Strokeaha.110.611210  0.562
2011 Dowlatshahi D, Smith EE, Flaherty ML, Ali M, Lyden P, Demchuk AM. Small intracerebral haemorrhages are associated with less haematoma expansion and better outcomes. International Journal of Stroke : Official Journal of the International Stroke Society. 6: 201-6. PMID 21557804 DOI: 10.1111/J.1747-4949.2010.00563.X  0.417
2011 Cucchiara B, Kasner S, Tanne D, Levine S, Demchuk A, Messe S, Sansing L, Lees K, Lyden P. Validation assessment of risk scores to predict postthrombolysis intracerebral haemorrhage. International Journal of Stroke : Official Journal of the International Stroke Society. 6: 109-11. PMID 21371270 DOI: 10.1111/J.1747-4949.2010.00556.X  0.478
2011 Mishra NK, Shuaib A, Lyden P, Diener HC, Grotta J, Davis S, Davalos A, Ashwood T, Wasiewski W, Lees KR. Home time is extended in patients with ischemic stroke who receive thrombolytic therapy: A validation study of home time as an outcome measure Stroke. 42: 1046-1050. PMID 21350199 DOI: 10.1161/Strokeaha.110.601302  0.516
2011 Sansing LH, Messe SR, Cucchiara BL, Lyden PD, Kasner SE. Anti-adrenergic medications and edema development after intracerebral hemorrhage. Neurocritical Care. 14: 395-400. PMID 21264527 DOI: 10.1007/S12028-010-9498-Z  0.313
2011 Manoonkitiwongsa PS, Schultz RL, Lyden PD. Safe and effective vascular endothelial cell growth factor (VEGF)-Based therapeutic angiogenesis for ischemic stroke: Insights from preclinical trials Therapeutic Angiogenesis For Vascular Diseases: Molecular Mechanisms and Targeted Clinical Approaches For the Treatment of Angiogenic Disease. 169-212. DOI: 10.1007/978-90-481-9495-7_8  0.328
2010 Lyden PD, Rapp K, Babcock T, Rothrock J. Ultra-rapid identification, triage, and enrollment of stroke patients into clinical trials. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 4: 106-13. PMID 26487611 DOI: 10.1016/S1052-3057(10)80118-1  0.528
2010 Mishra NK, Diener HC, Lyden PD, Bluhmki E, Lees KR. Influence of age on outcome from thrombolysis in acute stroke: a controlled comparison in patients from the Virtual International Stroke Trials Archive (VISTA). Stroke; a Journal of Cerebral Circulation. 41: 2840-8. PMID 21030710 DOI: 10.1161/Strokeaha.110.586206  0.472
2010 Mishra NK, Lyden P, Grotta JC, Lees KR. Thrombolysis is associated with consistent functional improvement across baseline stroke severity: A comparison of outcomes in patients from the virtual international stroke trials archive (VISTA) Stroke. 41: 2612-2617. PMID 20947852 DOI: 10.1161/Strokeaha.110.589317  0.544
2010 Albright KC, Branas CC, Meyer BC, Matherne-Meyer DE, Zivin JA, Lyden PD, Carr BG. ACCESS: acute cerebrovascular care in emergency stroke systems. Archives of Neurology. 67: 1210-8. PMID 20937948 DOI: 10.1001/Archneurol.2010.250  0.503
2010 Guluma KZ, Liu L, Hemmen TM, Acharya AB, Rapp KS, Raman R, Lyden PD. Therapeutic hypothermia is associated with a decrease in urine output in acute stroke patients. Resuscitation. 81: 1642-7. PMID 20817376 DOI: 10.1016/J.Resuscitation.2010.08.003  0.392
2010 Khatri P, Kleindorfer DO, Yeatts SD, Saver JL, Levine SR, Lyden PD, Moomaw CJ, Palesch YY, Jauch EC, Broderick JP. Strokes with minor symptoms: an exploratory analysis of the National Institute of Neurological Disorders and Stroke recombinant tissue plasminogen activator trials. Stroke; a Journal of Cerebral Circulation. 41: 2581-6. PMID 20814000 DOI: 10.1161/Strokeaha.110.593632  0.566
2010 Ovbiagele B, Lyden PD, Saver JL. Disability status at 1 month is a reliable proxy for final ischemic stroke outcome. Neurology. 75: 688-92. PMID 20733143 DOI: 10.1212/Wnl.0B013E3181Eee426  0.541
2010 Hemmen TM, Raman R, Guluma KZ, Meyer BC, Gomes JA, Cruz-Flores S, Wijman CA, Rapp KS, Grotta JC, Lyden PD. Intravenous thrombolysis plus hypothermia for acute treatment of ischemic stroke (ICTuS-L): final results. Stroke; a Journal of Cerebral Circulation. 41: 2265-70. PMID 20724711 DOI: 10.1161/Strokeaha.110.592295  0.563
2010 Chen B, Cheng Q, Yang K, Lyden PD. Thrombin mediates severe neurovascular injury during ischemia. Stroke; a Journal of Cerebral Circulation. 41: 2348-52. PMID 20705928 DOI: 10.1161/Strokeaha.110.584920  0.422
2010 Hemmen TM, Rapp KS, Emond JA, Raman R, Lyden PD. Analysis of the National Institute of Neurological Disorders and Stroke tissue plasminogen activator studies following European Cooperative Acute Stroke Study III patient selection criteria. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 19: 290-3. PMID 20471855 DOI: 10.1016/J.Jstrokecerebrovasdis.2009.06.001  0.5
2010 Cheung RT, Lyden PD, Tsoi TH, Huang Y, Liu M, Hon SF, Raman R, Liu L. Production and validation of Putonghua- and Cantonese-Chinese language National Institutes of Health Stroke Scale training and certification videos. International Journal of Stroke : Official Journal of the International Stroke Society. 5: 74-9. PMID 20446940 DOI: 10.1111/J.1747-4949.2010.00411.X  0.356
2010 Lyden PD, Meyer BC, Hemmen TM, Rapp KS. An ethical hierarchy for decision making during medical emergencies. Annals of Neurology. 67: 434-40. PMID 20437578 DOI: 10.1002/Ana.21997  0.325
2010 Stemer A, Lyden P. Evolution of the thrombolytic treatment window for acute ischemic stroke Current Neurology and Neuroscience Reports. 10: 29-33. PMID 20425223 DOI: 10.1007/S11910-009-0076-8  0.498
2010 Haley EC, Thompson JL, Grotta JC, Lyden PD, Hemmen TG, Brown DL, Fanale C, Libman R, Kwiatkowski TG, Llinas RH, Levine SR, Johnston KC, Buchsbaum R, Levy G, Levin B, et al. Phase IIB/III trial of tenecteplase in acute ischemic stroke: results of a prematurely terminated randomized clinical trial. Stroke; a Journal of Cerebral Circulation. 41: 707-11. PMID 20185783 DOI: 10.1161/Strokeaha.109.572040  0.459
2010 Rhoney DH, Coplin WM, Lin Y, Frankel M, Lyden PD, Levine SR. Time of day, outcome, and response to thrombolytic therapy: the National Institute of Neurological Disorders and Stroke Recombinant Tissue Plasminogen Activator Stroke Trial experience. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 19: 40-8. PMID 20123226 DOI: 10.1016/j.jstrokecerebrovasdis.2009.03.006  0.514
2009 Ali M, Sacco RL, Lees KR, Bath PMW, Bluhmki E, Claesson L, Curram J, Davis SM, Diener HC, Donnan GA, Fisher M, Gregson BA, Grotta J, Hacke W, Hennerici MG, ... ... Lyden P, et al. Primary end-point times, functional outcome and adverse event profile after acute ischaemic stroke International Journal of Stroke. 4: 432-442. PMID 19930052 DOI: 10.1111/j.1747-4949.2009.00348.x  0.468
2009 Gray LJ, Ali M, Lyden PD, Bath PM. Interconversion of the National Institutes of Health Stroke Scale and Scandinavian Stroke Scale in acute stroke. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 18: 466-8. PMID 19900650 DOI: 10.1016/J.Jstrokecerebrovasdis.2009.02.003  0.53
2009 Kamel H, Lees KR, Lyden PD, Teal PA, Shuaib A, Ali M, Johnston SC. Delayed detection of atrial fibrillation after ischemic stroke. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 18: 453-7. PMID 19900647 DOI: 10.1016/J.Jstrokecerebrovasdis.2009.01.012  0.506
2009 Chen B, Friedman B, Cheng Q, Tsai P, Schim E, Kleinfeld D, Lyden PD. Severe blood-brain barrier disruption and surrounding tissue injury. Stroke; a Journal of Cerebral Circulation. 40: e666-74. PMID 19893002 DOI: 10.1161/Strokeaha.109.551341  0.371
2009 Teal P, Davis S, Hacke W, Kaste M, Lyden PD, Fierus M. A randomized, double-blind, placebo-controlled trial to evaluate the efficacy, safety, tolerability, and pharmacokinetic/pharmacodynamic effects of a targeted exposure of intravenous repinotan in patients with acute ischemic stroke: modified Randomized Exposure Controlled Trial (mRECT). Stroke; a Journal of Cerebral Circulation. 40: 3518-25. PMID 19745176 DOI: 10.1161/Strokeaha.109.551382  0.488
2009 Meyer BC, Lyden PD. The modified National Institutes of Health Stroke Scale: its time has come. International Journal of Stroke : Official Journal of the International Stroke Society. 4: 267-73. PMID 19689755 DOI: 10.1111/J.1747-4949.2009.00294.X  0.476
2009 Lyden PD. Premature closure of the TUCSON trial: Stroke research is not for the faint of heart. Annals of Neurology. 66: 4-5. PMID 19670435 DOI: 10.1002/Ana.21764  0.486
2009 Cucchiara B, Kasner SE, Tanne D, Levine SR, Demchuk A, Messe SR, Sansing L, Lees KR, Lyden P. Factors associated with intracerebral hemorrhage after thrombolytic therapy for ischemic stroke: pooled analysis of placebo data from the Stroke-Acute Ischemic NXY Treatment (SAINT) I and SAINT II Trials Stroke; a Journal of Cerebral Circulation. 40: 3067-3072. PMID 19608993 DOI: 10.1161/Strokeaha.109.554386  0.569
2009 Lyden P, Raman R, Liu L, Emr M, Warren M, Marler J. National Institutes of Health Stroke Scale certification is reliable across multiple venues. Stroke. 40: 2507-11. PMID 19520998 DOI: 10.1161/Strokeaha.108.532069  0.498
2009 Pezzella FR, Picconi O, De Luca A, Lyden PD, Fiorelli M. Development of the Italian version of the National Institutes of Health Stroke Scale: It-NIHSS. Stroke; a Journal of Cerebral Circulation. 40: 2557-9. PMID 19520997 DOI: 10.1161/Strokeaha.108.534495  0.452
2009 Iramaneerat C, Smith EV, Millis SR, Lyden PD. Selecting a measurement model for the analysis of the National Institutes of Health Stroke Scale. The International Journal of Neuroscience. 119: 1042-59. PMID 19466638 DOI: 10.1080/00207450801909100  0.501
2009 Friedman B, Schachtrup C, Tsai PS, Shih AY, Akassoglou K, Kleinfeld D, Lyden PD. Acute vascular disruption and aquaporin 4 loss after stroke. Stroke; a Journal of Cerebral Circulation. 40: 2182-90. PMID 19372455 DOI: 10.1161/Strokeaha.108.523720  0.545
2009 Messé SR, Sansing LH, Cucchiara BL, Herman ST, Lyden PD, Kasner SE. Prophylactic antiepileptic drug use is associated with poor outcome following ICH. Neurocritical Care. 11: 38-44. PMID 19319701 DOI: 10.1007/S12028-009-9207-Y  0.338
2009 Hills NK, Josephson SA, Lyden PD, Johnston SC. Is the NIHSS certification process too lenient? Cerebrovascular Diseases (Basel, Switzerland). 27: 426-32. PMID 19295205 DOI: 10.1159/000209237  0.37
2009 Hemmen TM, Lyden PD. Hypothermia after acute ischemic stroke. Journal of Neurotrauma. 26: 387-91. PMID 19231919 DOI: 10.1089/Neu.2008.0574  0.571
2009 Shih AY, Friedman B, Drew PJ, Tsai PS, Lyden PD, Kleinfeld D. Active dilation of penetrating arterioles restores red blood cell flux to penumbral neocortex after focal stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 738-51. PMID 19174826 DOI: 10.1038/Jcbfm.2008.166  0.451
2009 Hemmen TM, Lyden PD. Multimodal neuroprotective therapy with induced hypothermia after ischemic stroke. Stroke; a Journal of Cerebral Circulation. 40: S126-8. PMID 19064802 DOI: 10.1161/Strokeaha.108.533083  0.492
2009 Albright KC, Raman R, Ernstrom K, Hallevi H, Martin-Schild S, Meyer BC, Meyer DM, Morales MM, Grotta JC, Lyden PD, Savitz SI. Can comprehensive stroke centers erase the 'weekend effect'? Cerebrovascular Diseases (Basel, Switzerland). 27: 107-13. PMID 19039213 DOI: 10.1159/000177916  0.583
2009 Adams HP, Lyden P. Assessment of a patient with stroke neurological examination and clinical rating scales. Handbook of Clinical Neurology. 94: 971-1009. PMID 18793885 DOI: 10.1016/S0072-9752(08)94048-3  0.518
2009 Adams HP, Lyden P. Assessment of a patient with stroke neurological examination and clinical rating scales Handbook of Clinical Neurology / Edited by P.J. Vinken and G.W. Bruyn. 94: 971-1009.  0.415
2008 Fink JN, Frampton CM, Lyden P, Lees KR. Does Hemispheric Lateralization Influence Functional and Cardiovascular Outcomes After Stroke? An Analysis of Placebo-Treated Patients From Prospective Acute Stroke Trials Stroke. 39: 3335-3340. PMID 18988910 DOI: 10.1161/Strokeaha.108.523365  0.574
2008 Ali M, Atula S, Bath PM, Grotta J, Hacke W, Lyden P, Marler JR, Sacco RL, Lees KR. Stroke outcome in clinical trial patients deriving from different countries. Stroke. 40: 35-40. PMID 18927457 DOI: 10.1161/Strokeaha.108.518035  0.569
2008 Lyden P. Thrombolytic therapy for acute stroke--not a moment to lose. The New England Journal of Medicine. 359: 1393-5. PMID 18815401 DOI: 10.1056/Nejme0806335  0.547
2008 Cucchiara B, Messe S, Sansing L, Kasner S, Lyden P. Hematoma Growth in Oral Anticoagulant Related Intracerebral Hemorrhage Stroke. 39: 2993-2996. PMID 18703803 DOI: 10.1161/Strokeaha.108.520668  0.388
2008 Meyer BC, Raman R, Hemmen T, Obler R, Zivin JA, Rao R, Thomas RG, Lyden PD. Efficacy of site-independent telemedicine in the STRokE DOC trial: a randomised, blinded, prospective study. The Lancet. Neurology. 7: 787-95. PMID 18676180 DOI: 10.1016/S1474-4422(08)70171-6  0.491
2008 Yenari M, Kitagawa K, Lyden P, Perez-Pinzon M. Metabolic Downregulation: A Key to Successful Neuroprotection? Stroke. 39: 2910-2917. PMID 18658035 DOI: 10.1161/Strokeaha.108.514471  0.326
2008 Jensen MB, Chacon MR, Sattin JA, Aleu A, Lyden PD. The promise and potential pitfalls of serum biomarkers for ischemic stroke and transient ischemic attack. The Neurologist. 14: 243-6. PMID 18617850 DOI: 10.1097/Nrl.0B013E31815A9945  0.482
2008 Ovbiagele B, Starkman S, Teal P, Lyden P, Kaste M, Davis SM, Hacke W, Fierus M, Saver JL. Serum calcium as prognosticator in ischemic stroke. Stroke; a Journal of Cerebral Circulation. 39: 2231-6. PMID 18583560 DOI: 10.1161/Strokeaha.107.513499  0.52
2008 Diener HC, Lees KR, Lyden P, Grotta J, Davalos A, Davis SM, Shuaib A, Ashwood T, Wasiewski W, Alderfer V, HÃ¥rdemark HG, Rodichok L. NXY-059 for the treatment of acute stroke: pooled analysis of the SAINT I and II Trials. Stroke; a Journal of Cerebral Circulation. 39: 1751-8. PMID 18369171 DOI: 10.1161/Strokeaha.107.503334  0.549
2008 Lyden PD. Code stroke in the cath lab. Journal of the American College of Cardiology. 51: 912. PMID 18308159 DOI: 10.1016/j.jacc.2007.10.053  0.396
2008 Hemmen TM, Meyer BC, McClean TL, Lyden PD. Identification of nonischemic stroke mimics among 411 code strokes at the University of California, San Diego, Stroke Center. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 17: 23-5. PMID 18190817 DOI: 10.1016/J.Jstrokecerebrovasdis.2007.09.008  0.569
2008 Guluma KZ, Oh H, Yu SW, Meyer BC, Rapp K, Lyden PD. Effect of endovascular hypothermia on acute ischemic edema: morphometric analysis of the ICTuS trial. Neurocritical Care. 8: 42-7. PMID 17922082 DOI: 10.1007/S12028-007-9009-Z  0.532
2007 Meyer BC, Raman R, Rao R, Fellman RD, Beer J, Werner J, Zivin JA, Lyden PD. The STRokE DOC trial technique: 'video clip, drip, and/or ship'. International Journal of Stroke : Official Journal of the International Stroke Society. 2: 281-7. PMID 18705930 DOI: 10.1111/J.1747-4949.2007.00153.X  0.567
2007 Lyden P, Wahlgren NG. Mechanisms of action of neuroprotectants in stroke. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 9: 9-14. PMID 17895214 DOI: 10.1053/Jscd.2000.19316  0.448
2007 Shuaib A, Lees KR, Lyden P, Grotta J, Davalos A, Davis SM, Diener HC, Ashwood T, Wasiewski WW, Emeribe U. NXY-059 for the treatment of acute ischemic stroke. The New England Journal of Medicine. 357: 562-71. PMID 17687131 DOI: 10.1056/Nejmoa070240  0.581
2007 Lyden PD, Shuaib A, Lees KR, Davalos A, Davis SM, Diener HC, Grotta JC, Ashwood TJ, Hardemark HG, Svensson HH, Rodichok L, Wasiewski WW, Ahlberg G. Safety and tolerability of NXY-059 for acute intracerebral hemorrhage: the CHANT Trial. Stroke; a Journal of Cerebral Circulation. 38: 2262-9. PMID 17569876 DOI: 10.1161/Strokeaha.106.472746  0.45
2007 Adams HP, del Zoppo G, Alberts MJ, Bhatt DL, Brass L, Furlan A, Grubb RL, Higashida RT, Jauch EC, Kidwell C, Lyden PD, Morgenstern LB, Qureshi AI, Rosenwasser RH, Scott PA, et al. Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Circulation. 115: e478-534. PMID 17515473 DOI: 10.1161/Circulationaha.107.181486  0.56
2007 Adams HP, del Zoppo G, Alberts MJ, Bhatt DL, Brass L, Furlan A, Grubb RL, Higashida RT, Jauch EC, Kidwell C, Lyden PD, Morgenstern LB, Qureshi AI, Rosenwasser RH, Scott PA, et al. Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: the American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Stroke; a Journal of Cerebral Circulation. 38: 1655-711. PMID 17431204 DOI: 10.1161/Strokeaha.107.181486  0.56
2007 Millis SR, Straube D, Iramaneerat C, Smith EV, Lyden P. Measurement properties of the National Institutes of Health Stroke Scale for people with right- and left-hemisphere lesions: further analysis of the clomethiazole for acute stroke study-ischemic (class-I) trial. Archives of Physical Medicine and Rehabilitation. 88: 302-8. PMID 17321821 DOI: 10.1016/J.Apmr.2006.12.027  0.532
2007 Hemmen TM, Lyden PD. Induced hypothermia for acute stroke. Stroke; a Journal of Cerebral Circulation. 38: 794-9. PMID 17261741 DOI: 10.1161/01.Str.0000247920.15708.Fa  0.524
2007 Yu SW, Friedman B, Cheng Q, Lyden PD. Stroke-evoked angiogenesis results in a transient population of microvessels. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 755-63. PMID 16883352 DOI: 10.1038/Sj.Jcbfm.9600378  0.438
2007 Lyden PD. January 23 highlight and commentary: Using tPA for acute stroke in a rural setting Neurology. 68: 247. DOI: 10.1212/01.Wnl.0000255799.59117.34  0.547
2007 Hemmen TM, Lyden PD. Response to letter by den Hertog et al [5] Stroke. 38: e132. DOI: 10.1161/Strokeaha.107.488197  0.495
2006 Lyden PD, Krieger D, Yenari M, Dietrich WD. Therapeutic hypothermia for acute stroke. International Journal of Stroke : Official Journal of the International Stroke Society. 1: 9-19. PMID 18706063 DOI: 10.1111/J.1747-4949.2005.00011.X  0.501
2006 Sattin JA, Olson SE, Liu L, Raman R, Lyden PD. An expedited code stroke protocol is feasible and safe. Stroke; a Journal of Cerebral Circulation. 37: 2935-9. PMID 17095736 DOI: 10.1161/01.Str.0000249057.44420.4B  0.533
2006 Lees KR, Davalos A, Davis SM, Diener HC, Grotta J, Lyden P, Shuaib A, Ashwood T, Hardemark HG, Wasiewski W, Emeribe U, Zivin JA. Additional outcomes and subgroup analyses of NXY-059 for acute ischemic stroke in the SAINT I trial. Stroke; a Journal of Cerebral Circulation. 37: 2970-8. PMID 17068304 DOI: 10.1161/01.Str.0000249410.91473.44  0.574
2006 Lyden PD, Lees KR, Davis SM. Alteplase for acute stroke revisited: the first 10 years. The Lancet. Neurology. 5: 722-4. PMID 16914399 DOI: 10.1016/S1474-4422(06)70530-0  0.54
2006 Guluma KZ, Hemmen TM, Olsen SE, Rapp KS, Lyden PD. A trial of therapeutic hypothermia via endovascular approach in awake patients with acute ischemic stroke: methodology. Academic Emergency Medicine : Official Journal of the Society For Academic Emergency Medicine. 13: 820-7. PMID 16766740 DOI: 10.1197/J.Aem.2006.03.559  0.39
2006 Lyden PD. Should all stroke patients receive tissue plasminogen activator therapy, despite mild or improving symptoms? Nature Clinical Practice. Cardiovascular Medicine. 3: 184-5. PMID 16568123 DOI: 10.1038/Ncpcardio0511  0.476
2006 Manoonkitiwongsa PS, Schultz RL, Whitter EF, Lyden PD. Contraindications of VEGF-based therapeutic angiogenesis: effects on macrophage density and histology of normal and ischemic brains. Vascular Pharmacology. 44: 316-25. PMID 16530019 DOI: 10.1016/J.Vph.2006.01.008  0.381
2006 Lees KR, Zivin JA, Ashwood T, Davalos A, Davis SM, Diener HC, Grotta J, Lyden P, Shuaib A, HÃ¥rdemark HG, Wasiewski WW. NXY-059 for acute ischemic stroke. The New England Journal of Medicine. 354: 588-600. PMID 16467546 DOI: 10.1056/Nejmoa052980  0.565
2006 Nishimura N, Schaffer CB, Friedman B, Tsai PS, Lyden PD, Kleinfeld D. Targeted insult to subsurface cortical blood vessels using ultrashort laser pulses: three models of stroke. Nature Methods. 3: 99-108. PMID 16432519 DOI: 10.1038/Nmeth844  0.318
2005 Lyden PD, Allgren RL, Ng K, Akins P, Meyer B, Al-Sanani F, Lutsep H, Dobak J, Matsubara BS, Zivin J. Intravascular Cooling in the Treatment of Stroke (ICTuS): early clinical experience. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 14: 107-14. PMID 17904009 DOI: 10.1016/J.Jstrokecerebrovasdis.2005.01.001  0.542
2005 Libman R, Kwiakowski T, Lyden P, Grotta JC, Tilley BC, Fagen SC, Levine SR, Broderick JP, Lin Y, Lewandowski C, Frankel MR. Asymptomatic hemorrhagic transformation of cerebral infarction does not worsen long-term outcome. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 14: 50-4. PMID 17904000 DOI: 10.1016/J.Jstrokecerebrovasdis.2004.11.002  0.574
2005 Hemphill JC, Lyden P. Stroke thrombolysis in the elderly: risk or benefit? Neurology. 65: 1690-1. PMID 16344508 DOI: 10.1212/01.Wnl.0000192631.39824.93  0.563
2005 Lyden P, Raman R, Liu L, Grotta J, Broderick J, Olson S, Shaw S, Spilker J, Meyer B, Emr M, Warren M, Marler J. NIHSS training and certification using a new digital video disk is reliable. Stroke; a Journal of Cerebral Circulation. 36: 2446-9. PMID 16224093 DOI: 10.1161/01.Str.0000185725.42768.92  0.501
2005 Levine SR, Broderick JP, Brott T, DeGraba T, Fagan SC, Frankel MR, Grotta JC, Haley EC, Hamilton S, Kwiatkowski T, Lewandowski CA, Lin Y, Libman R, Lu M, Lyden P, et al. Recombinant tissue plasminogen activator for minor strokes: The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study experience Annals of Emergency Medicine. 46: 243-252. PMID 16126134 DOI: 10.1016/J.Annemergmed.2005.02.013  0.579
2005 Lu M, Lyden PD, Brott TG, Hamilton S, Broderick JP, Grotta JC. Beyond subgroup analysis: improving the clinical interpretation of treatment effects in stroke research. Journal of Neuroscience Methods. 143: 209-16. PMID 15814153 DOI: 10.1016/J.Jneumeth.2004.10.002  0.425
2005 Kwiatkowski T, Libman R, Tilley BC, Lewandowski C, Grotta JC, Lyden P, Levine SR, Brott T. The impact of imbalances in baseline stroke severity on outcome in the National Institute of Neurological Disorders and Stroke Recombinant Tissue Plasminogen Activator Stroke Study. Annals of Emergency Medicine. 45: 377-84. PMID 15795715 DOI: 10.1016/J.Annemergmed.2004.06.021  0.583
2005 Meyer BC, Lyden PD, Al-Khoury L, Cheng Y, Raman R, Fellman R, Beer J, Rao R, Zivin JA. Prospective reliability of the STRokE DOC wireless/site independent telemedicine system. Neurology. 64: 1058-60. PMID 15781827 DOI: 10.1212/01.Wnl.0000154601.26653.E7  0.539
2005 Haley EC, Lyden PD, Johnston KC, Hemmen TM. A pilot dose-escalation safety study of tenecteplase in acute ischemic stroke. Stroke; a Journal of Cerebral Circulation. 36: 607-12. PMID 15692126 DOI: 10.1161/01.Str.0000154872.73240.E9  0.539
2004 Lyden P, Claesson L, Havstad S, Ashwood T, Lu M. Factor analysis of the National Institutes of Health Stroke Scale in patients with large strokes. Jama Neurology. 61: 1677-1680. PMID 15534178 DOI: 10.1001/Archneur.61.11.1677  0.563
2004 Manoonkitiwongsa PS, Schultz RL, McCreery DB, Whitter EF, Lyden PD. Neuroprotection of ischemic brain by vascular endothelial growth factor is critically dependent on proper dosage and may be compromised by angiogenesis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 24: 693-702. PMID 15181377 DOI: 10.1097/01.Wcb.0000126236.54306.21  0.402
2004 Hacke W, Donnan G, Fieschi C, Kaste M, von Kummer R, Broderick JP, Brott T, Frankel M, Grotta JC, Haley EC, Kwiatkowski T, Levine SR, Lewandowski C, Lu M, Lyden P, et al. Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet (London, England). 363: 768-74. PMID 15016487 DOI: 10.1016/S0140-6736(04)15692-4  0.556
2004 Cucchiara BL, Kasner SE, Wolk DA, Lyden PD, Knappertz VA, Ashwood T, Odergren T, Nordlund A. Early impairment in consciousness predicts mortality after hemispheric ischemic stroke. Critical Care Medicine. 32: 241-5. PMID 14707586 DOI: 10.1097/01.Ccm.0000104113.36384.81  0.552
2004 Lyden PD, Broderick J. Thrombolytic therapy: Introduction Stroke. 35: 2720-2721. DOI: 10.1161/01.Str.0000143239.45446.9D  0.507
2003 Zingmark P, Ekblom M, Odergren T, Ashwood T, Lyden P, Karlsson MO, Jonsson EN. Population pharmacokinetics of clomethiazole and its effect on the natural course of sedation in acute stroke patients British Journal of Clinical Pharmacology. 56: 173-183. PMID 12895190 DOI: 10.1046/J.0306-5251.2003.01850.X  0.473
2003 Cucchiara B, Kasner SE, Wolk DA, Lyden PD, Knappertz VA, Ashwood T, Odergren T, Nordlund A. Lack of hemispheric dominance for consciousness in acute ischaemic stroke. Journal of Neurology, Neurosurgery, and Psychiatry. 74: 889-92. PMID 12810773 DOI: 10.1136/Jnnp.74.7.889  0.564
2003 Chimowitz MI, Howlett-Smith H, Calcaterra A, Lessard N, Stern B, Lynn M, Hertzberg V, Cotsonis G, Swanson S, Tutu-Gxashe T, Griffin P, Kosinski A, Chester C, Asbury W, Rogers S, ... ... Lyden P, et al. Design, progress and challenges of a double-blind trial of warfarin versus aspirin for symptomatic intracranial arterial stenosis Neuroepidemiology. 22: 106-117. PMID 12656117 DOI: 10.1159/000068744  0.547
2003 Lyden P. Early major ischemic changes on computed tomography should not preclude use of tissue plasminogen activator. Stroke. 34: 821-2. PMID 12624317 DOI: 10.1161/01.Str.0000059431.80687.D8  0.431
2003 Schaffer CB, Ebner FF, Nishimura N, Friedman B, Tsai PS, Schroeder LF, Lyden PD, Kleinfeld D. Two-photon fluorescence microscopy of collateral blood flow following photothrombotic stroke in rat neocortex Frontiers in Optics. DOI: 10.1364/Fio.2003.Thpp2  0.317
2003 Schaffer CB, Tsai PS, Nishimura N, Schroeder LF, Friedman B, Lyden PD, Ebner FF, Kleinfeld D. All optical thrombotic stroke model for near-surface blood vessels in rat: Focal illumination of exogenous photosensitizers combined with real-time two-photon imaging Proceedings of Spie - the International Society For Optical Engineering. 4978: 222-231. DOI: 10.1117/12.484208  0.3
2002 Goldstein LB, Lyden P, Mathias SD, Colman SS, Pasta DJ, Albers G, Atkinson R, Kelley G, Ng K, Rylander A. Telephone assessment of functioning and well-being following stroke: is it feasible? Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 11: 80-7. PMID 17903861 DOI: 10.1053/Jscd.2002.126691  0.478
2002 Bruno A, Levine SR, Frankel MR, Brott TG, Lin Y, Tilley BC, Lyden PD, Broderick JP, Kwiatkowski TG, Fineberg SE. Admission glucose level and clinical outcomes in the NINDS rt-PA Stroke Trial. Neurology. 59: 669-74. PMID 12221155 DOI: 10.1212/Wnl.59.5.669  0.536
2002 Meyer BC, Hemmen TM, Jackson CM, Lyden PD. Modified National Institutes of Health Stroke Scale for use in stroke clinical trials: prospective reliability and validity. Stroke; a Journal of Cerebral Circulation. 33: 1261-6. PMID 11988601 DOI: 10.1161/01.Str.0000015625.87603.A7  0.497
2002 Lyden PD. Systematic review of nimodipine. Stroke; a Journal of Cerebral Circulation. 33: 639-40. PMID 11823683 DOI: 10.1161/Str.33.2.639  0.435
2002 Lyden P, Shuaib A, Ng K, Levin K, Atkinson RP, Rajput A, Wechsler L, Ashwood T, Claesson L, Odergren T, Salazar-Grueso E. Clomethiazole Acute Stroke Study in ischemic stroke (CLASS-I): final results. Stroke. 33: 122-8. PMID 11779900 DOI: 10.1161/Hs0102.101478  0.583
2002 Lyden P, Lu M, Kwiatkowski T, Frankel M, Levine S, Broderick J, Brott T. Thrombolysis in patients with transient neurologic deficits. Neurology. 57: 2125-8. PMID 11739841 DOI: 10.1212/Wnl.57.11.2125  0.566
2001 Patel SC, Levine SR, Tilley BC, Grotta JC, Lu M, Frankel M, Haley EC, Brott TG, Broderick JP, Horowitz S, Lyden PD, Lewandowski CA, Marler JR, Welch KM. Lack of clinical significance of early ischemic changes on computed tomography in acute stroke. Jama. 286: 2830-8. PMID 11735758 DOI: 10.1001/Jama.286.22.2830  0.522
2001 Manoonkitiwongsa PS, Jackson-Friedman C, McMillan PJ, Schultz RL, Lyden PD. Angiogenesis after stroke is correlated with increased numbers of macrophages: the clean-up hypothesis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 21: 1223-31. PMID 11598500 DOI: 10.1097/00004647-200110000-00011  0.395
2001 Lyden P, Jacoby M, Schim J, Albers G, Mazzeo P, Ashwood T, Nordlund A, Odergren T. The Clomethiazole Acute Stroke Study in tissue-type plasminogen activator-treated stroke (CLASS-T): final results. Neurology. 57: 1199-205. PMID 11591835 DOI: 10.1212/Wnl.57.7.1199  0.556
2001 Broderick J, Lu M, Jackson C, Pancioli A, Tilley BC, Fagan SC, Kothari R, Levine SR, Marler JR, Lyden PD, Haley EC, Brott T, Grotta JC. Apolipoprotein E phenotype and the efficacy of intravenous tissue plasminogen activator in acute ischemic stroke. Annals of Neurology. 49: 736-44. PMID 11409425 DOI: 10.1002/Ana.1058  0.459
2001 Lyden PD, Lu M, Levine SR, Brott TG, Broderick J. A modified National Institutes of Health Stroke Scale for use in stroke clinical trials: preliminary reliability and validity. Stroke; a Journal of Cerebral Circulation. 32: 1310-7. PMID 11387492 DOI: 10.1161/01.Str.32.6.1310  0.534
2001 Chapman DF, Lyden P, Lapchak PA, Nunez S, Thibodeaux H, Zivin J. Comparison of TNK with wild-type tissue plasminogen activator in a rabbit embolic stroke model. Stroke; a Journal of Cerebral Circulation. 32: 748-52. PMID 11239197 DOI: 10.1161/01.Str.32.3.748  0.485
2001 Grotta JC, Welch KM, Fagan SC, Lu M, Frankel MR, Brott T, Levine SR, Lyden PD. Clinical deterioration following improvement in the NINDS rt-PA Stroke Trial. Stroke; a Journal of Cerebral Circulation. 32: 661-8. PMID 11239184 DOI: 10.1161/01.Str.32.3.661  0.49
2001 Manoonkitiwongsa PS, Jackson-Friedman C, McMillan PJ, Schultz RL, Lyden PD. Intra-Arterial Infusion Of Vascular Endothelial Growth Factor In Normal And Ischemic Brains Has No Effect On Angiogenesis Stroke. 32: 356-356. DOI: 10.1161/01.Str.32.Suppl_1.356-B  0.316
2000 Wahlgren NG, Lyden P. Neuroprotectants in the treatment of stroke--an overview. Journal of Stroke & Cerebrovascular Diseases. 9: 32-35. PMID 17895218 DOI: 10.1053/Jscd.2000.19320  0.581
2000 Wechsler L, Lyden P. For How Long Is Brain Tissue Salvageable? Thrombolysis-Based Evidence Journal of Stroke & Cerebrovascular Diseases. 9: 21-23. PMID 17895216 DOI: 10.1053/Jscd.2000.19321  0.529
2000 Albers GW, Alberts MJ, Broderick JP, Lyden PD, Sacco RL. Recent advances in stroke management. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 9: 95-105. PMID 17895205 DOI: 10.1053/Jscd.2000.5865  0.593
2000 Broderick JP, Lu M, Kothari R, Levine SR, Lyden PD, Haley EC, Brott TG, Grotta J, Tilley BC, Marler JR, Frankel M. Finding the most powerful measures of the effectiveness of tissue plasminogen activator in the NINDS tPA stroke trial. Stroke; a Journal of Cerebral Circulation. 31: 2335-41. PMID 11022060 DOI: 10.1161/01.Str.31.10.2335  0.498
2000 Lyden PD, Jackson-Friedman C, Shin C, Hassid S. Synergistic combinatorial stroke therapy: A quantal bioassay of a GABA agonist and a glutamate antagonist. Experimental Neurology. 163: 477-89. PMID 10833323 DOI: 10.1006/Exnr.2000.7394  0.451
2000 Lyden PD, Shuaib A, Ng K, Atkinson R, Ashwood T, Nordlund A, Odergren T. The clomethiazole acute stroke study in hemorrhagic stroke (CLASS-H): Final results Journal of Stroke and Cerebrovascular Diseases. 9: 268-275. DOI: 10.1053/Jscd.2000.18735  0.568
2000 Lyden PD, Brockington CD. Intravenous Stroke Therapy: Why You Do It and When Journal of Vascular and Interventional Radiology. 11: 335-340. DOI: 10.1016/S1051-0443(00)70138-2  0.529
2000 Brockington CD, Lyden PD. Stroke prevention and acute intervention: Review of recent advances Formulary. 35: 328-342.  0.378
1999 Lyden PD, Marler JR. Acute medical therapy. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 8: 139-45. PMID 17895156 DOI: 10.1016/S1052-3057(99)80019-6  0.57
1999 Lyden PD. Thrombolysis for acute stroke. Progress in Cardiovascular Diseases. 42: 175-83. PMID 10598919 DOI: 10.1016/S0033-0620(99)70001-0  0.547
1999 Woo D, Broderick JP, Kothari RU, Lu M, Brott T, Lyden PD, Marler JR, Grotta JC. Does the National Institutes of Health Stroke Scale favor left hemisphere strokes? NINDS t-PA Stroke Study Group. Stroke; a Journal of Cerebral Circulation. 30: 2355-9. PMID 10548670 DOI: 10.1161/01.Str.30.11.2355  0.559
1999 Lyden P, Lu M, Jackson C, Marler J, Kothari R, Brott T, Zivin J. Underlying structure of the National Institutes of Health stroke scale: Results of a factor analysis Stroke. 30: 2347-2354. PMID 10548669 DOI: 10.1161/01.Str.30.11.2347  0.563
1999 Brockington CD, Lyden PD. Criteria for selection of older patients for thrombolytic therapy. Clinics in Geriatric Medicine. 15: 721-39. PMID 10499932 DOI: 10.1016/S0749-0690(18)30028-4  0.416
1999 Grotta JC, Chiu D, Lu M, Patel S, Levine SR, Tilley BC, Brott TG, Haley EC, Lyden PD, Kothari R, Frankel M, Lewandowski CA, Libman R, Kwiatkowski T, Broderick JP, et al. Agreement and variability in the interpretation of early CT changes in stroke patients qualifying for intravenous rtPA therapy. Stroke; a Journal of Cerebral Circulation. 30: 1528-33. PMID 10436095 DOI: 10.1161/01.Str.30.8.1528  0.493
1998 Lyden PD, Ashwood T, Claesson L, Odergren T, Friday GH, Martin-Munley S. The clomethiazole acute stroke study in ischemic, hemorrhagic, and t-PA treated stroke: Design of a phase III trial in the united states and canada. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 7: 435-41. PMID 17895123 DOI: 10.1016/S1052-3057(98)80128-6  0.577
1998 Lyden PD, Hantson L. Assessment scales for the evaluation of stroke patients. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 7: 113-27. PMID 17895068 DOI: 10.1016/S1052-3057(98)80138-9  0.501
1998 Fagan SC, Bowes MP, Lyden PD, Zivin JA. Acute hypertension promotes hemorrhagic transformation in a rabbit embolic stroke model: effect of labetalol. Experimental Neurology. 150: 153-8. PMID 9514832 DOI: 10.1006/Exnr.1997.6756  0.407
1998 Johnston KC, Li JY, Lyden PD, Hanson SK, Feasby TE, Adams RJ, Faught RE, Haley EC. Medical and neurological complications of ischemic stroke: experience from the RANTTAS trial. RANTTAS Investigators. Stroke; a Journal of Cerebral Circulation. 29: 447-53. PMID 9472888 DOI: 10.1161/01.Str.29.2.447  0.474
1998 Roos JA, Jackson‐Friedman C, Lyden P. Effects of Hyperbaric Oxygen on Neurologic Outcome for Cerebral Ischemia in Rats Academic Emergency Medicine. 5: 18-24. PMID 9444337 DOI: 10.1111/J.1553-2712.1998.Tb02569.X  0.371
1998 Lyden PD. Managing acute stroke: Intravenous vs intra-arterial tPA Journal of Critical Illness. 13: 669.  0.416
1997 Lyden PD. Neuroprotection: before and after thrombolysis. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 6: 198-9. PMID 17894996 DOI: 10.1016/S1052-3057(97)80010-9  0.447
1997 Lyden PD. Thrombolysis: findings and lessons of the clinical trials. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 6: 195-7. PMID 17894995 DOI: 10.1016/S1052-3057(97)80009-2  0.57
1997 Tilley BC, Lyden PD, Brott TG, Lu M, Levine SR, Welch KM. Total quality improvement method for reduction of delays between emergency department admission and treatment of acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Archives of Neurology. 54: 1466-74. PMID 9400355 DOI: 10.1001/Archneur.1997.00550240020008  0.511
1997 Jackson-Friedman C, Lyden PD, Nunez S, Jin A, Zweifler R. High dose baclofen is neuroprotective but also causes intracerebral hemorrhage: a quantal bioassay study using the intraluminal suture occlusion method. Experimental Neurology. 147: 346-52. PMID 9344559 DOI: 10.1006/Exnr.1997.6637  0.359
1997 Lyden PD, Lonzo LM, Nunez SY, Dockstader T, Mathieu-Costello O, Zivin JA. Effect of ischemic cerebral volume changes on behavior. Behavioural Brain Research. 87: 59-67. PMID 9331474 DOI: 10.1016/S0166-4328(96)02269-3  0.352
1997 Lyden PD, Grotta JC, Levine SR, Marler JR, Frankel MR, Brott TG. Intravenous thrombolysis for acute stroke. Neurology. 49: 14-20. PMID 9222164 DOI: 10.1212/Wnl.49.1.14  0.556
1997 Lyden PD, Jackson-Friedman C, Lonzo-Doktor L. Medical therapy for intracerebral hematoma with the gamma-aminobutyric acid-A agonist muscimol. Stroke; a Journal of Cerebral Circulation. 28: 387-91. PMID 9040695 DOI: 10.1161/01.Str.28.2.387  0.324
1997 Clark WM, Lyden PD, Madden KP, Zivin JA. Thrombolytic therapy in acute ischemic stroke. The New England Journal of Medicine. 336: 65-6; author reply 6. PMID 8984333  0.465
1997 Frankel MR, Clark WM, Lyden PD, Madden KP, Zivin JA, Firstenberg MS, Hommel M, Cornu C, Boutitie F. Thrombolytic therapy in acute ischemic stroke [1] (multiple letters) New England Journal of Medicine. 336: 65-67. PMID 8984332 DOI: 10.1056/NEJM199701023360112  0.466
1996 Tilley BC, Marler J, Geller NL, Lu M, Legler J, Brott T, Lyden P, Grotta J. Use of a global test for multiple outcomes in stroke trials with application to the National Institute of Neurological Disorders and Stroke t-PA Stroke Trial. Stroke. 27: 2136-42. PMID 8898828 DOI: 10.1161/01.Str.27.11.2136  0.565
1996 Adams HP, Brott TG, Furlan AJ, Gomez CR, Grotta J, Helgason CM, Kwiatkowski T, Lyden PD, Marler JR, Torner J, Feinberg W, Mayberg M, Thies W. Guidelines for thrombolytic therapy for acute stroke: a supplement to the guidelines for the management of patients with acute ischemic stroke. A statement for healthcare professionals from a Special Writing Group of the Stroke Council, American Heart Association. Circulation. 94: 1167-74. PMID 8790069 DOI: 10.1161/01.Cir.94.5.1167  0.496
1996 Adams HP, Brott TG, Furlan AJ, Gomez CR, Grotta J, Helgason CM, Kwiatkowski T, Lyden PD, Marler JR, Torner J, Feinberg W, Mayberg M, Thies W. Guidelines for Thrombolytic Therapy for Acute Stroke: a Supplement to the Guidelines for the Management of Patients with Acute Ischemic Stroke. A statement for healthcare professionals from a Special Writing Group of the Stroke Council, American Heart Association. Stroke; a Journal of Cerebral Circulation. 27: 1711-8. PMID 8784157  0.478
1995 Zweifler RM, Lyden PD, Taft B, Kelly N, Rothrock JF. Impact of race and ethnicity on ischemic stroke. The University of California at San Diego Stroke Data Bank. Stroke; a Journal of Cerebral Circulation. 26: 245-8. PMID 7831696 DOI: 10.1161/01.Str.26.2.245  0.556
1995 Rothrock JF, Clark WM, Lyden PD. Spontaneous early improvement following ischemic stroke. Stroke; a Journal of Cerebral Circulation. 26: 1358-60. PMID 7631337 DOI: 10.1161/01.Str.26.8.1358  0.593
1995 Lyden P, Lonzo L, Nunez S. Combination chemotherapy extends the therapeutic window to 60 minutes after stroke. Journal of Neurotrauma. 12: 223-30. PMID 7629868 DOI: 10.1089/Neu.1995.12.223  0.473
1995 Grotta J, Kothari M, Welch K, Broderick J, Tilley B, Brott T, Marler, Lyden P, O'Byrne P. Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. The New England Journal of Medicine. PMID 7477192 DOI: 10.1056/Nejm199512143332401  0.565
1994 Lyden PD, Zweifler R, Mahdavi Z, Lonzo L. A rapid, reliable, and valid method for measuring infarct and brain compartment volumes from computed tomographic scans. Stroke; a Journal of Cerebral Circulation. 25: 2421-8. PMID 7974584 DOI: 10.1161/01.Str.25.12.2421  0.499
1994 Lyden P, Brott T, Tilley B, Welch KM, Mascha EJ, Levine S, Haley EC, Grotta J, Marler J. Improved reliability of the NIH Stroke Scale using video training. NINDS TPA Stroke Study Group. Stroke; a Journal of Cerebral Circulation. 25: 2220-6. PMID 7974549 DOI: 10.1161/01.Str.25.11.2220  0.514
1994 Lyden PD, Lonzo L. Combination therapy protects ischemic brain in rats. A glutamate antagonist plus a gamma-aminobutyric acid agonist. Stroke; a Journal of Cerebral Circulation. 25: 189-96. PMID 7903492 DOI: 10.1161/01.Str.25.1.189  0.422
1993 Lyden PD, Zivin JA. Hemorrhagic transformation after cerebral ischemia: mechanisms and incidence. Cerebrovascular and Brain Metabolism Reviews. 5: 1-16. PMID 8452759  0.459
1993 Rothrock JF, Lyden PD, Brody ML, Taft-Alvarez B, Kelly N, Mayer J, Wiederholt WC. An analysis of ischemic stroke in an urban southern California population. The University of California, San Diego, Stroke Data Bank. Archives of Internal Medicine. 153: 619-24. PMID 8439224 DOI: 10.1001/Archinte.1993.00410050055007  0.577
1993 Rothrock J, North J, Madden K, Lyden P, Fleck P, Dittrich H. Migraine and migrainous stroke: risk factors and prognosis. Neurology. 43: 2473-2473. PMID 8255442 DOI: 10.1212/Wnl.43.12.2473  0.549
1992 Lyden PD, Zivin JA, Chabolla DR, Jacobs MA, Gage FH. Quantitative effects of cerebral infarction on spatial learning in rats. Experimental Neurology. 116: 122-32. PMID 1577120 DOI: 10.1016/0014-4886(92)90160-R  0.399
1992 Lyden PD, Hedges B. Protective effect of synaptic inhibition during cerebral ischemia in rats and rabbits. Stroke; a Journal of Cerebral Circulation. 23: 1463-9; discussion 1. PMID 1357785 DOI: 10.1161/01.Str.23.10.1463  0.401
1991 Clark WM, Madden KP, Lyden PD, Zivin JA. Cerebral hemorrhagic risk of aspirin or heparin therapy with thrombolytic treatment in rabbits. Stroke; a Journal of Cerebral Circulation. 22: 872-6. PMID 1906646 DOI: 10.1161/01.Str.22.7.872  0.437
1991 Lyden PD, Lau GT. A critical appraisal of stroke evaluation and rating scales. Stroke; a Journal of Cerebral Circulation. 22: 1345-52. PMID 1750040 DOI: 10.1161/01.Str.22.11.1345  0.549
1990 Lyden PD, Madden KP, Clark WM, Sasse KC, Zivin JA. Incidence of cerebral hemorrhage after treatment with tissue plasminogen activator or streptokinase following embolic stroke in rabbits [corrected]. Stroke; a Journal of Cerebral Circulation. 21: 1589-93. PMID 2122552 DOI: 10.1161/01.Str.21.11.1589  0.502
1989 Lyden PD. Thrombolytic therapy for acute stroke. The Western Journal of Medicine. 150: 577. PMID 18750584 DOI: 10.1007/978-3-319-07575-4  0.566
1989 Bracha HS, Lyden PD, Khansarinia S. Delayed emergence of striatal dopaminergic hyperactivity after anterolateral ischemic cortical lesions in humans; evidence from turning behavior. Biological Psychiatry. 25: 265-74. PMID 2914151 DOI: 10.1016/0006-3223(89)90174-1  0.354
1989 Atkinson CS, Press GA, Lyden P, Katz B. The ferret as an animal model in cerebrovascular research. Stroke. 20: 1085-8. PMID 2756540 DOI: 10.1161/01.Str.20.8.1085  0.359
1989 Rothrock JF, Dittrich HC, McAllen S, Taft BJ, Lyden PD. Acute anticoagulation following cardioembolic stroke. Stroke; a Journal of Cerebral Circulation. 20: 730-4. PMID 2728037 DOI: 10.1161/01.Str.20.6.730  0.582
1989 Lyden PD, Zivin JA, Clark WA, Madden K, Sasse KC, Mazzarella VA, Terry RD, Press GA. Tissue plasminogen activator-mediated thrombolysis of cerebral emboli and its effect on hemorrhagic infarction in rabbits. Neurology. 39: 703-8. PMID 2496332 DOI: 10.1212/Wnl.39.5.703  0.475
1988 Katz B, Sofonio M, Lyden PD, Mitchell MD. Prostaglandin concentrations in cerebrospinal fluid of rabbits under normal and ischemic conditions. Stroke; a Journal of Cerebral Circulation. 19: 349-51. PMID 3354021 DOI: 10.1161/01.Str.19.3.349  0.467
1988 Rothrock JF, Rubenstein R, Lyden PD. Ischemic stroke associated with methamphetamine inhalation. Neurology. 38: 589-92. PMID 3352918 DOI: 10.1212/Wnl.38.4.589  0.571
1988 Rothrock JF, Lyden PD, Yee J, Wiederholt WC. 'Crescendo' transient ischemic attacks: clinical and angiographic correlations. Neurology. 38: 198-201. PMID 3340280 DOI: 10.1212/Wnl.38.2.198  0.386
1988 Rothrock JF, Walicke P, Swenson MR, Lyden PD, Logan WR. Migrainous stroke. Archives of Neurology. 45: 63-7. PMID 3337678 DOI: 10.1001/archneur.1988.00520250069023  0.504
1988 Kochhar A, Zivin JA, Lyden PD, Mazzarella V. Glutamate antagonist therapy reduces neurologic deficits produced by focal central nervous system ischemia. Archives of Neurology. 45: 148-53. PMID 3277597 DOI: 10.1001/Archneur.1988.00520260034016  0.361
1988 Rothrock JF, Swenson MR, Lyden PD. Migrainous stroke. Stroke; a Journal of Cerebral Circulation. 19: 1306. PMID 3176091  0.482
1988 Zivin JA, Lyden PD, DeGirolami U, Kochhar A, Mazzarella V, Hemenway CC, Johnston P. Tissue plasminogen activator. Reduction of neurologic damage after experimental embolic stroke. Archives of Neurology. 45: 387-91. PMID 3128254 DOI: 10.1001/Archneur.1988.00520280033012  0.532
1988 Lyden PD, Alving LI, Zivin JA, Rothrock JF. Hemodilution with low-molecular-weight hydroxyethyl starch after experimental focal cerebral ischemia in rabbits. Stroke; a Journal of Cerebral Circulation. 19: 223-7. PMID 2449746 DOI: 10.1161/01.Str.19.2.223  0.428
1987 Rothrock J, Taft BJ, Lyden PD. A new approach to stroke management. American Family Physician. 36: 189-97. PMID 3673864  0.462
1987 Lyden PD, Zivin JA, Soll M, Sitzer M, Rothrock JF, Alksne J. Intracerebral hemorrhage after experimental embolic infarction. Anticoagulation. Archives of Neurology. 44: 848-50. PMID 3632395 DOI: 10.1001/Archneur.1987.00520200052018  0.512
1987 Rothrock JF, Lyden PD, Hesselink JR, Brown JJ, Healy ME. Brain magnetic resonance imaging in the evaluation of lacunar stroke. Stroke; a Journal of Cerebral Circulation. 18: 781-6. PMID 3603605 DOI: 10.1161/01.Str.18.4.781  0.409
1987 Zivin JA, DeGirolami U, Kochhar A, Lyden PD, Mazzarella V, Hemenway CC, Henry ME. A model for quantitative evaluation of embolic stroke therapy. Brain Research. 435: 305-9. PMID 3427458 DOI: 10.1016/0006-8993(87)91613-1  0.487
1987 Rothrock JF, Lyden P, Yee J, Wiederholt W. Unstable Carotid Artery Syndrome: Clinical Management, Risks and Outcome Vascular Surgery. 21: 248-256. DOI: 10.1177/153857448702100404  0.429
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