Jonah R. Chan - Publications

Neurology and Program in Neuroscience University of California, San Francisco, San Francisco, CA 

69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Pan S, Mayoral SR, Choi HS, Chan JR, Kheirbek MA. Preservation of a remote fear memory requires new myelin formation. Nature Neuroscience. PMID 32042175 DOI: 10.1038/s41593-019-0582-1  0.44
2020 Wang F, Ren SY, Chen JF, Liu K, Li RX, Li ZF, Hu B, Niu JQ, Xiao L, Chan JR, Mei F. Myelin degeneration and diminished myelin renewal contribute to age-related deficits in memory. Nature Neuroscience. PMID 32042174 DOI: 10.1038/s41593-020-0588-8  0.36
2020 Xin W, Chan JR. That Wasn't a Complement-Too Much C3 in Demyelinating Disease. Immunity. 52: 11-13. PMID 31951547 DOI: 10.1016/j.immuni.2019.12.014  1
2019 Rankin KA, Mei F, Kim K, Shen YA, Mayoral SR, Desponts C, Lorrain DS, Green AJ, Baranzini SE, Chan JR, Bove R. Selective estrogen receptor modulators enhance CNS remyelination independent of estrogen receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30696729 DOI: 10.1523/JNEUROSCI.1530-18.2019  0.44
2018 Mayoral SR, Etxeberria A, Shen YA, Chan JR. Initiation of CNS Myelination in the Optic Nerve Is Dependent on Axon Caliber. Cell Reports. 25: 544-550.e3. PMID 30332636 DOI: 10.1016/j.celrep.2018.09.052  0.44
2018 Wang F, Yang YJ, Yang N, Chen XJ, Huang NX, Zhang J, Wu Y, Liu Z, Gao X, Li T, Pan GQ, Liu SB, Li HL, Fancy SPJ, Xiao L, ... Chan JR, et al. Enhancing Oligodendrocyte Myelination Rescues Synaptic Loss and Improves Functional Recovery after Chronic Hypoxia. Neuron. PMID 30078577 DOI: 10.1016/j.neuron.2018.07.017  0.36
2018 Jiang M, Rao R, Wang J, Wang J, Xu L, Wu LM, Chan JR, Wang H, Lu QR. The TSC1-mTOR-PLK axis regulates the homeostatic switch from Schwann cell proliferation to myelination in a stage-specific manner. Glia. PMID 29722913 DOI: 10.1002/glia.23449  0.44
2017 Cree BAC, Niu J, Hoi KK, Zhao C, Caganap SD, Henry RG, Dao DQ, Zollinger DR, Mei F, Shen YA, Franklin RJM, Ullian EM, Xiao L, Chan JR, Fancy SPJ. Clemastine rescues myelination defects and promotes functional recovery in hypoxic brain injury. Brain : a Journal of Neurology. PMID 29244098 DOI: 10.1093/brain/awx312  0.44
2017 Petersen MA, Ryu JK, Chang KJ, Etxeberria A, Bardehle S, Mendiola AS, Kamau-Devers W, Fancy SPJ, Thor A, Bushong EA, Baeza-Raja B, Syme CA, Wu MD, Rios Coronado PE, Meyer-Franke A, ... ... Chan JR, et al. Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage. Neuron. PMID 29103804 DOI: 10.1016/j.neuron.2017.10.008  0.4
2017 Green AJ, Gelfand JM, Cree BA, Bevan C, Boscardin WJ, Mei F, Inman J, Arnow S, Devereux M, Abounasr A, Nobuta H, Zhu A, Friessen M, Gerona R, von Büdingen HC, ... ... Chan JR, et al. Clemastine fumarate as a remyelinating therapy for multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover trial. Lancet (London, England). PMID 29029896 DOI: 10.1016/S0140-6736(17)32346-2  0.36
2017 Dombrowski Y, O'Hagan T, Dittmer M, Penalva R, Mayoral SR, Bankhead P, Fleville S, Eleftheriadis G, Zhao C, Naughton M, Hassan R, Moffat J, Falconer J, Boyd A, Hamilton P, ... ... Chan JR, et al. Regulatory T cells promote myelin regeneration in the central nervous system. Nature Neuroscience. PMID 28288125 DOI: 10.1038/nn.4528  0.44
2016 Mei F, Lehmann-Horn K, Shen YA, Rankin KA, Stebbins KJ, Lorrain DS, Pekarek K, A Sagan S, Xiao L, Teuscher C, von Büdingen HC, Wess J, Lawrence JJ, Green AJ, Fancy SP, ... ... Chan JR, et al. Accelerated remyelination during inflammatory demyelination prevents axonal loss and improves functional recovery. Elife. 5. PMID 27671734 DOI: 10.7554/eLife.18246  1
2016 Redmond SA, Mei F, Eshed-Eisenbach Y, Osso LA, Leshkowitz D, Shen YA, Kay JN, Aurrand-Lions M, Lyons DA, Peles E, Chan JR. Somatodendritic Expression of JAM2 Inhibits Oligodendrocyte Myelination. Neuron. PMID 27499083 DOI: 10.1016/j.neuron.2016.07.021  0.68
2016 Mei F, Mayoral SR, Nobuta H, Wang F, Desponts C, Lorrain DS, Xiao L, Green AJ, Rowitch D, Whistler J, Chan JR. Identification of the Kappa-Opioid Receptor as a Therapeutic Target for Oligodendrocyte Remyelination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7925-35. PMID 27466337 DOI: 10.1523/JNEUROSCI.1493-16.2016  1
2016 Etxeberria A, Hokanson KC, Dao DQ, Mayoral SR, Mei F, Redmond SA, Ullian EM, Chan JR. Dynamic Modulation of Myelination in Response to Visual Stimuli Alters Optic Nerve Conduction Velocity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 6937-48. PMID 27358452 DOI: 10.1523/JNEUROSCI.0908-16.2016  1
2016 Lee S, Shang Y, Redmond SA, Urisman A, Tang AA, Li KH, Burlingame AL, Pak RA, Jovičić A, Gitler AD, Wang J, Gray NS, Seeley WW, Siddique T, Bigio EH, ... ... Chan JR, et al. Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis. Neuron. PMID 27321923 DOI: 10.1016/j.neuron.2016.05.021  0.68
2016 Wu LM, Wang J, Conidi A, Zhao C, Wang H, Ford Z, Zhang L, Zweier C, Ayee BG, Maurel P, Zwijsen A, Chan JR, Jankowski MP, Huylebroeck D, Lu QR. Zeb2 recruits HDAC-NuRD to inhibit Notch and controls Schwann cell differentiation and remyelination. Nature Neuroscience. PMID 27294509 DOI: 10.1038/nn.4322  1
2016 Mayoral SR, Chan JR. The environment rules: spatiotemporal regulation of oligodendrocyte differentiation. Current Opinion in Neurobiology. 39: 47-52. PMID 27128881 DOI: 10.1016/j.conb.2016.04.002  0.44
2016 Chang KJ, Redmond SA, Chan JR. Remodeling myelination: implications for mechanisms of neural plasticity. Nature Neuroscience. 19: 190-197. PMID 26814588 DOI: 10.1038/nn.4200  1
2016 Tsai HH, Niu J, Munji R, Davalos D, Chang J, Zhang H, Tien AC, Kuo CJ, Chan JR, Daneman R, Fancy SP. Oligodendrocyte precursors migrate along vasculature in the developing nervous system. Science (New York, N.Y.). 351: 379-84. PMID 26798014 DOI: 10.1126/science.aad3839  1
2016 Hernandez M, Patzig J, Mayoral SR, Costa KD, Chan JR, Casaccia P. Mechanostimulation Promotes Nuclear and Epigenetic Changes in Oligodendrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 806-13. PMID 26791211 DOI: 10.1523/JNEUROSCI.2873-15.2016  1
2015 Osso LA, Chan JR. Astrocytes Underlie Neuroinflammatory Memory Impairment. Cell. 163: 1574-6. PMID 26687350 DOI: 10.1016/j.cell.2015.12.001  1
2015 von Büdingen HC, Mei F, Greenfield A, Jahn S, Shen YA, Reid HH, McKemy DD, Chan JR. The myelin oligodendrocyte glycoprotein directly binds nerve growth factor to modulate central axon circuitry. The Journal of Cell Biology. PMID 26347141 DOI: 10.1083/jcb.201504106  0.36
2015 Fatah FA, Lin YC, Lee TY, Yang KC, Liu RX, Chan JR, Hsu HT, Miyamoto Y, Chang EY. Potential of enhancement mode In0.65Ga0.35As/InAs/In0.65Ga0.35As HEMTs for using in high-speed and low-power logic applications Ecs Journal of Solid State Science and Technology. 4: N157-N159. DOI: 10.1149/2.0171512jss  0.32
2014 Shen YA, Chen Y, Dao DQ, Mayoral SR, Wu L, Meijer D, Ullian EM, Chan JR, Lu QR. Phosphorylation of LKB1/Par-4 establishes Schwann cell polarity to initiate and control myelin extent. Nature Communications. 5: 4991. PMID 25255972 DOI: 10.1038/ncomms5991  1
2014 Burns ML, Malott TM, Metcalf KJ, Hackel BJ, Chan JR, Shusta EV. Directed evolution of brain-derived neurotrophic factor for improved folding and expression in Saccharomyces cerevisiae. Applied and Environmental Microbiology. 80: 5732-42. PMID 25015885 DOI: 10.1128/AEM.01466-14  1
2014 Mei F, Fancy SP, Shen YA, Niu J, Zhao C, Presley B, Miao E, Lee S, Mayoral SR, Redmond SA, Etxeberria A, Xiao L, Franklin RJ, Green A, Hauser SL, ... Chan JR, et al. Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis. Nature Medicine. 20: 954-60. PMID 24997607 DOI: 10.1038/nm.3618  1
2014 Molofsky AV, Kelley KW, Tsai HH, Redmond SA, Chang SM, Madireddy L, Chan JR, Baranzini SE, Ullian EM, Rowitch DH. Astrocyte-encoded positional cues maintain sensorimotor circuit integrity. Nature. 509: 189-94. PMID 24776795 DOI: 10.1038/nature13161  1
2013 Hauser SL, Chan JR, Oksenberg JR. Multiple sclerosis: Prospects and promise. Annals of Neurology. 74: 317-27. PMID 23955638 DOI: 10.1002/ana.24009  1
2013 Mei F, Wang H, Liu S, Niu J, Wang L, He Y, Etxeberria A, Chan JR, Xiao L. Stage-specific deletion of Olig2 conveys opposing functions on differentiation and maturation of oligodendrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 8454-62. PMID 23658182 DOI: 10.1523/JNEUROSCI.2453-12.2013  1
2013 Lee S, Chong SY, Tuck SJ, Corey JM, Chan JR. A rapid and reproducible assay for modeling myelination by oligodendrocytes using engineered nanofibers. Nature Protocols. 8: 771-82. PMID 23589937 DOI: 10.1038/nprot.2013.039  1
2013 Mei F, Christin Chong SY, Chan JR. Myelin-based inhibitors of oligodendrocyte myelination: clues from axonal growth and regeneration. Neuroscience Bulletin. 29: 177-88. PMID 23516141 DOI: 10.1007/s12264-013-1319-x  1
2013 Yu Y, Chen Y, Kim B, Wang H, Zhao C, He X, Liu L, Liu W, Wu LM, Mao M, Chan JR, Wu J, Lu QR. Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation. Cell. 152: 248-61. PMID 23332759 DOI: 10.1016/j.cell.2012.12.006  1
2012 Yamauchi J, Miyamoto Y, Torii T, Takashima S, Kondo K, Kawahara K, Nemoto N, Chan JR, Tsujimoto G, Tanoue A. Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development. Science Signaling. 5: ra69. PMID 23012656 DOI: 10.1126/scisignal.2002802  1
2012 Lee S, Leach MK, Redmond SA, Chong SY, Mellon SH, Tuck SJ, Feng ZQ, Corey JM, Chan JR. A culture system to study oligodendrocyte myelination processes using engineered nanofibers. Nature Methods. 9: 917-22. PMID 22796663 DOI: 10.1038/nmeth.2105  1
2012 Redmond SA, Chan JR. Neuroscience. Revitalizing remyelination--the answer is circulating. Science (New York, N.Y.). 336: 161-2. PMID 22499927 DOI: 10.1126/science.1221689  1
2012 Chong SY, Rosenberg SS, Fancy SP, Zhao C, Shen YA, Hahn AT, McGee AW, Xu X, Zheng B, Zhang LI, Rowitch DH, Franklin RJ, Lu QR, Chan JR. Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination. Proceedings of the National Academy of Sciences of the United States of America. 109: 1299-304. PMID 22160722 DOI: 10.1073/pnas.1113540109  1
2012 Tep C, Kim ML, Opincariu LI, Limpert AS, Chan JR, Appel B, Carter BD, Yoon SO. Brain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3) protein. The Journal of Biological Chemistry. 287: 1600-8. PMID 22128191 DOI: 10.1074/jbc.M111.312736  1
2011 Fancy SP, Chan JR, Baranzini SE, Franklin RJ, Rowitch DH. Myelin regeneration: a recapitulation of development? Annual Review of Neuroscience. 34: 21-43. PMID 21692657 DOI: 10.1146/annurev-neuro-061010-113629  1
2011 Lewallen KA, Shen YA, De la Torre AR, Ng BK, Meijer D, Chan JR. Assessing the role of the cadherin/catenin complex at the Schwann cell-axon interface and in the initiation of myelination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 3032-43. PMID 21414924 DOI: 10.1523/JNEUROSCI.4345-10.2011  1
2010 Kim YE, Chen J, Langen R, Chan JR. Monitoring apoptosis and neuronal degeneration by real-time detection of phosphatidylserine externalization using a polarity-sensitive indicator of viability and apoptosis. Nature Protocols. 5: 1396-405. PMID 20671723 DOI: 10.1038/nprot.2010.101  1
2010 Chong SY, Chan JR. Tapping into the glial reservoir: cells committed to remaining uncommitted. The Journal of Cell Biology. 188: 305-12. PMID 20142420 DOI: 10.1083/jcb.200905111  1
2010 Kim YE, Chen J, Chan JR, Langen R. Engineering a polarity-sensitive biosensor for time-lapse imaging of apoptotic processes and degeneration. Nature Methods. 7: 67-73. PMID 19966809 DOI: 10.1038/nmeth.1405  1
2009 Hahn AT, Chan JR. A collaboration conducive to conduction: matching axonal density to oligodendroglial number (Commentary on Kawai et al.). The European Journal of Neuroscience. 30: 2029. PMID 20128841 DOI: 10.1111/j.1460-9568.2009.07050.x  1
2009 Rosenberg SS, Chan JR. Modulating myelination: knowing when to say Wnt. Genes & Development. 23: 1487-93. PMID 19571178 DOI: 10.1101/gad.1824009  1
2009 Rosenberg SS, Chan JR. Modulating myelination: Knowing when to say Wnt (Genes and Development (2009) 23 (1487-1493)) Genes and Development. 23: 1980.  1
2008 Rosenberg SS, Kelland EE, Tokar E, De la Torre AR, Chan JR. The geometric and spatial constraints of the microenvironment induce oligodendrocyte differentiation. Proceedings of the National Academy of Sciences of the United States of America. 105: 14662-7. PMID 18787118 DOI: 10.1073/pnas.0805640105  1
2008 Yamauchi J, Miyamoto Y, Chan JR, Tanoue A. ErbB2 directly activates the exchange factor Dock7 to promote Schwann cell migration. The Journal of Cell Biology. 181: 351-65. PMID 18426980 DOI: 10.1083/jcb.200709033  1
2007 Miyamoto Y, Yamauchi J, Chan JR, Okada A, Tomooka Y, Hisanaga S, Tanoue A. Cdk5 regulates differentiation of oligodendrocyte precursor cells through the direct phosphorylation of paxillin. Journal of Cell Science. 120: 4355-66. PMID 18042622 DOI: 10.1242/jcs.018218  1
2007 Rosenberg SS, Powell BL, Chan JR. Receiving mixed signals: uncoupling oligodendrocyte differentiation and myelination. Cellular and Molecular Life Sciences : Cmls. 64: 3059-68. PMID 17876524 DOI: 10.1007/s00018-007-7265-x  1
2007 Ng BK, Chen L, Mandemakers W, Cosgaya JM, Chan JR. Anterograde transport and secretion of brain-derived neurotrophic factor along sensory axons promote Schwann cell myelination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7597-603. PMID 17626221 DOI: 10.1523/JNEUROSCI.0563-07.2007  1
2007 Chan JR. Myelination: all about Rac 'n' roll. The Journal of Cell Biology. 177: 953-5. PMID 17576794 DOI: 10.1083/jcb.200705105  1
2007 Lee X, Yang Z, Shao Z, Rosenberg SS, Levesque M, Pepinsky RB, Qiu M, Miller RH, Chan JR, Mi S. NGF regulates the expression of axonal LINGO-1 to inhibit oligodendrocyte differentiation and myelination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 220-5. PMID 17202489 DOI: 10.1523/JNEUROSCI.4175-06.2007  1
2006 Rosenberg SS, Ng BK, Chan JR. The quest for remyelination: a new role for neurotrophins and their receptors. Brain Pathology (Zurich, Switzerland). 16: 288-94. PMID 17107598 DOI: 10.1111/j.1750-3639.2006.00035.x  1
2006 Chan JR, Jolicoeur C, Yamauchi J, Elliott J, Fawcett JP, Ng BK, Cayouette M. The polarity protein Par-3 directly interacts with p75NTR to regulate myelination. Science (New York, N.Y.). 314: 832-6. PMID 17082460 DOI: 10.1126/science.1134069  1
2005 Yamauchi J, Miyamoto Y, Tanoue A, Shooter EM, Chan JR. Ras activation of a Rac1 exchange factor, Tiam1, mediates neurotrophin-3-induced Schwann cell migration. Proceedings of the National Academy of Sciences of the United States of America. 102: 14889-94. PMID 16203995 DOI: 10.1073/pnas.0507125102  1
2005 Yamauchi J, Chan JR, Miyamoto Y, Tsujimoto G, Shooter EM. The neurotrophin-3 receptor TrkC directly phosphorylates and activates the nucleotide exchange factor Dbs to enhance Schwann cell migration. Proceedings of the National Academy of Sciences of the United States of America. 102: 5198-203. PMID 15758069 DOI: 10.1073/pnas.0501160102  1
2005 Saxena S, Howe CL, Cosgaya JM, Steiner P, Hirling H, Chan JR, Weis J, Krüttgen A. Differential endocytic sorting of p75NTR and TrkA in response to NGF: a role for late endosomes in TrkA trafficking. Molecular and Cellular Neurosciences. 28: 571-87. PMID 15737746 DOI: 10.1016/j.mcn.2004.11.011  1
2004 Chan JR, Watkins TA, Cosgaya JM, Zhang C, Chen L, Reichardt LF, Shooter EM, Barres BA. NGF controls axonal receptivity to myelination by Schwann cells or oligodendrocytes. Neuron. 43: 183-91. PMID 15260955 DOI: 10.1016/j.neuron.2004.06.024  1
2004 Yamauchi J, Chan JR, Shooter EM. Neurotrophins regulate Schwann cell migration by activating divergent signaling pathways dependent on Rho GTPases. Proceedings of the National Academy of Sciences of the United States of America. 101: 8774-9. PMID 15161978 DOI: 10.1073/pnas.0402795101  1
2004 Ullian EM, Harris BT, Wu A, Chan JR, Barres BA. Schwann cells and astrocytes induce synapse formation by spinal motor neurons in culture. Molecular and Cellular Neurosciences. 25: 241-51. PMID 15019941 DOI: 10.1016/j.mcn.2003.10.011  1
2004 Wu YJ, Krüttgen A, Möller JC, Shine D, Chan JR, Shooter EM, Cosgaya JM. Nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 are sorted to dense-core vesicles and released via the regulated pathway in primary rat cortical neurons. Journal of Neuroscience Research. 75: 825-34. PMID 14994343 DOI: 10.1002/jnr.20048  1
2003 Yamauchi J, Chan JR, Shooter EM. Neurotrophin 3 activation of TrkC induces Schwann cell migration through the c-Jun N-terminal kinase pathway. Proceedings of the National Academy of Sciences of the United States of America. 100: 14421-6. PMID 14614136 DOI: 10.1073/pnas.2336152100  1
2002 Cosgaya JM, Chan JR, Shooter EM. The neurotrophin receptor p75NTR as a positive modulator of myelination. Science (New York, N.Y.). 298: 1245-8. PMID 12424382 DOI: 10.1126/science.1076595  1
2002 Date ES, Teraoka JK, Chan J, Kingery WS. Effects of elbow flexion on radial nerve motor conduction velocity Electromyography and Clinical Neurophysiology. 42: 51-56. PMID 11851010  1
2001 Chan JR, Cosgaya JM, Wu YJ, Shooter EM. Neurotrophins are key mediators of the myelination program in the peripheral nervous system. Proceedings of the National Academy of Sciences of the United States of America. 98: 14661-8. PMID 11717413 DOI: 10.1073/pnas.251543398  1
2000 Chan JR, Rodriguez-Waitkus PM, Ng BK, Liang P, Glaser M. Progesterone synthesized by Schwann cells during myelin formation regulates neuronal gene expression. Molecular Biology of the Cell. 11: 2283-95. PMID 10888668  1
1998 Chan JR, Phillips LJ, Glaser M. Glucocorticoids and progestins signal the initiation and enhance the rate of myelin formation. Proceedings of the National Academy of Sciences of the United States of America. 95: 10459-64. PMID 9724725 DOI: 10.1073/pnas.95.18.10459  1
1997 Bilderback TR, Chan JR, Harvey JJ, Glaser M. Measurement of the rate of myelination using a fluorescent analogue of ceramide. Journal of Neuroscience Research. 49: 497-507. PMID 9285525 DOI: 10.1002/(SICI)1097-4547(19970815)49:4<497::AID-JNR10>3.0.CO;2-U  1
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