David D. McKemy - Publications

Affiliations: 
University of Southern California, Los Angeles, CA, United States 
Area:
somatosensation

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Yang C, Wei C, Alam S, Chen X, McKemy DD. The neurotrophic factor artemin and its receptor GFRα3 mediate migraine-like pain via the ion channel TRPM8. Biorxiv : the Preprint Server For Biology. PMID 39314341 DOI: 10.1101/2024.09.09.611532  0.469
2023 Yang C, Yamaki S, Jung T, Kim B, Huyhn R, McKemy DD. Endogenous inflammatory mediators produced by injury activate TRPV1 and TRPA1 nociceptors to induce sexually dimorphic cold pain that is dependent on TRPM8 and GFRα3. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 36898840 DOI: 10.1523/JNEUROSCI.2303-22.2023  0.413
2023 Yang C, Yamaki S, Jung T, Kim B, Huyhn R, McKemy DD. Endogenous inflammatory mediators produced by injury activate TRPV1 and TRPA1 nociceptors to induce sexually dimorphic cold pain that is dependent on TRPM8 and GFRα3. Biorxiv : the Preprint Server For Biology. PMID 36747719 DOI: 10.1101/2023.01.23.525238  0.401
2022 Wei C, Kim B, McKemy DD. Transient receptor potential melastatin 8 is required for nitroglycerin- and calcitonin gene-related peptide-induced migraine-like pain behaviors in mice. Pain. PMID 35353773 DOI: 10.1097/j.pain.0000000000002635  0.473
2020 Yamaki S, Chau A, Gonzales L, McKemy DD. Nociceptive afferent phenotyping reveals that TRPA1 promotes cold pain via neurogenic inflammation upstream of the neurotrophic factor receptor GFRα3 and the menthol receptor TRPM8. Pain. PMID 32826761 DOI: 10.1097/j.pain.0000000000002043  0.582
2019 Ramakrishna C, Corleto J, Ruegger PM, Logan GD, Peacock BB, Mendonca S, Yamaki S, Adamson T, Ermel R, McKemy D, Borneman J, Cantin EM. Dominant Role of the Gut Microbiota in Chemotherapy Induced Neuropathic Pain. Scientific Reports. 9: 20324. PMID 31889131 DOI: 10.1038/S41598-019-56832-X  0.374
2019 Blair NT, Carvacho I, Chaudhuri D, Clapham DE, DeCaen P, Delling M, Doerner JF, Fan L, Ha K, Jordt SE, Julius D, Kahle KT, Liu B, McKemy D, Nilius B, et al. Transient Receptor Potential channels (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f78/2019.4  0.467
2018 McKemy DD. Molecular basis of peripheral innocuous cold sensitivity. Handbook of Clinical Neurology. 156: 57-67. PMID 30454609 DOI: 10.1016/B978-0-444-63912-7.00003-5  0.591
2018 Ongun S, Sarkisian A, McKemy DD. Selective cold pain inhibition by targeted block of TRPM8-expressing neurons with quaternary lidocaine derivative QX-314. Communications Biology. 1: 53. PMID 30271936 DOI: 10.1038/s42003-018-0062-2  0.418
2017 Palkar R, Ongun S, Catich E, Li N, Borad N, Sarkisian A, McKemy DD. Cooling relief of acute and chronic itch requires TRPM8 channels and neurons. The Journal of Investigative Dermatology. PMID 29288650 DOI: 10.1016/j.jid.2017.12.025  0.589
2016 McCoy DD, Palkar R, Yang Y, Ongun S, McKemy DD. Cellular permeation of large molecules mediated by TRPM8 channels. Neuroscience Letters. PMID 28038937 DOI: 10.1016/J.Neulet.2016.12.063  0.785
2016 Lippoldt EK, Ongun S, Kusaka GK, McKemy DD. Inflammatory and neuropathic cold allodynia are selectively mediated by the neurotrophic factor receptor GFRα3. Proceedings of the National Academy of Sciences of the United States of America. PMID 27051069 DOI: 10.1073/pnas.1603294113  0.472
2015 von Büdingen HC, Mei F, Greenfield A, Jahn S, Shen YA, Reid HH, McKemy DD, Chan JR. The myelin oligodendrocyte glycoprotein directly binds nerve growth factor to modulate central axon circuitry. The Journal of Cell Biology. PMID 26347141 DOI: 10.1083/Jcb.201504106  0.354
2015 Kim YS, Kim TH, McKemy DD, Bae YC. Expression of vesicular glutamate transporters in transient receptor potential melastatin 8 (TRPM8)-positive dental afferents in the mouse. Neuroscience. PMID 26166724 DOI: 10.1016/j.neuroscience.2015.07.013  0.486
2015 Palkar R, Lippoldt EK, McKemy DD. The molecular and cellular basis of thermosensation in mammals. Current Opinion in Neurobiology. 34: 14-19. PMID 25622298 DOI: 10.1016/j.conb.2015.01.010  0.556
2014 Kim YS, Park JH, Choi SJ, Bae JY, Ahn DK, McKemy DD, Bae YC. Central connectivity of transient receptor potential melastatin 8-expressing axons in the brain stem and spinal dorsal horn. Plos One. 9: e94080. PMID 24710558 DOI: 10.1371/journal.pone.0094080  0.428
2013 Lippoldt EK, Elmes RR, McCoy DD, Knowlton WM, McKemy DD. Artemin, a glial cell line-derived neurotrophic factor family member, induces TRPM8-dependent cold pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 12543-52. PMID 23884957 DOI: 10.1523/Jneurosci.5765-12.2013  0.804
2013 McCoy DD, Zhou L, Nguyen AK, Watts AG, Donovan CM, McKemy DD. Enhanced insulin clearance in mice lacking TRPM8 channels. American Journal of Physiology. Endocrinology and Metabolism. 305: E78-88. PMID 23651844 DOI: 10.1152/Ajpendo.00542.2012  0.727
2013 Ramachandran R, Hyun E, Zhao L, Lapointe TK, Chapman K, Hirota CL, Ghosh S, McKemy DD, Vergnolle N, Beck PL, Altier C, Hollenberg MD. TRPM8 activation attenuates inflammatory responses in mouse models of colitis. Proceedings of the National Academy of Sciences of the United States of America. 110: 7476-81. PMID 23596210 DOI: 10.1073/Pnas.1217431110  0.417
2013 McKemy DD. The molecular and cellular basis of cold sensation. Acs Chemical Neuroscience. 4: 238-47. PMID 23421674 DOI: 10.1021/cn300193h  0.584
2013 Knowlton WM, Palkar R, Lippoldt EK, McCoy DD, Baluch F, Chen J, McKemy DD. A sensory-labeled line for cold: TRPM8-expressing sensory neurons define the cellular basis for cold, cold pain, and cooling-mediated analgesia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2837-48. PMID 23407943 DOI: 10.1523/Jneurosci.1943-12.2013  0.808
2012 Osborne M, Gomez D, Feng Z, McEwen C, Beltran J, Cirillo K, El-Khodor B, Lin MY, Li Y, Knowlton WM, McKemy DD, Bogdanik L, Butts-Dehm K, Martens K, Davis C, et al. Characterization of behavioral and neuromuscular junction phenotypes in a novel allelic series of SMA mouse models. Human Molecular Genetics. 21: 4431-47. PMID 22802075 DOI: 10.1093/Hmg/Dds285  0.733
2011 Knowlton WM, Daniels RL, Palkar R, McCoy DD, McKemy DD. Pharmacological blockade of TRPM8 ion channels alters cold and cold pain responses in mice. Plos One. 6: e25894. PMID 21984952 DOI: 10.1371/Journal.Pone.0025894  0.791
2011 McCoy DD, Knowlton WM, McKemy DD. Scraping through the ice: uncovering the role of TRPM8 in cold transduction. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 300: R1278-87. PMID 21411765 DOI: 10.1152/Ajpregu.00631.2010  0.814
2011 McKemy DD. A spicy family tree: TRPV1 and its thermoceptive and nociceptive lineage. The Embo Journal. 30: 453-5. PMID 21285975 DOI: 10.1038/emboj.2010.350  0.584
2011 Knowlton WM, McKemy DD. TRPM8: from cold to cancer, peppermint to pain. Current Pharmaceutical Biotechnology. 12: 68-77. PMID 20932257 DOI: 10.2174/138920111793937961  0.833
2010 Daniels RL, McKemy DD. Design and construction of a two-temperature preference behavioral assay for undergraduate neuroscience laboratories. Journal of Undergraduate Neuroscience Education : June : a Publication of Fun, Faculty For Undergraduate Neuroscience. 9: A51-6. PMID 23494724  0.661
2010 Takashima Y, Ma L, McKemy DD. The development of peripheral cold neural circuits based on TRPM8 expression. Neuroscience. 169: 828-42. PMID 20580783 DOI: 10.1016/J.Neuroscience.2010.05.039  0.644
2010 Knowlton WM, Bifolck-Fisher A, Bautista DM, McKemy DD. TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo. Pain. 150: 340-50. PMID 20542379 DOI: 10.1016/j.pain.2010.05.021  0.818
2009 Mandadi S, Nakanishi ST, Takashima Y, Dhaka A, Patapoutian A, McKemy DD, Whelan PJ. Locomotor networks are targets of modulation by sensory transient receptor potential vanilloid 1 and transient receptor potential melastatin 8 channels. Neuroscience. 162: 1377-97. PMID 19482068 DOI: 10.1016/J.Neuroscience.2009.05.063  0.629
2009 Stucky CL, Dubin AE, Jeske NA, Malin SA, McKemy DD, Story GM. Roles of transient receptor potential channels in pain. Brain Research Reviews. 60: 2-23. PMID 19203589 DOI: 10.1016/j.brainresrev.2008.12.018  0.572
2009 Carr RW, Pianova S, McKemy DD, Brock JA. Action potential initiation in the peripheral terminals of cold-sensitive neurones innervating the guinea-pig cornea. The Journal of Physiology. 587: 1249-64. PMID 19171652 DOI: 10.1113/jphysiol.2008.167023  0.38
2009 Daniels RL, Takashima Y, McKemy DD. Activity of the neuronal cold sensor TRPM8 is regulated by phospholipase C via the phospholipid phosphoinositol 4,5-bisphosphate. The Journal of Biological Chemistry. 284: 1570-82. PMID 19019830 DOI: 10.1074/jbc.M807270200  0.786
2008 Wang YY, Chang RB, Waters HN, McKemy DD, Liman ER. The nociceptor ion channel TRPA1 is potentiated and inactivated by permeating calcium ions. The Journal of Biological Chemistry. 283: 32691-703. PMID 18775987 DOI: 10.1074/Jbc.M803568200  0.349
2007 Takashima Y, Daniels RL, Knowlton W, Teng J, Liman ER, McKemy DD. Diversity in the neural circuitry of cold sensing revealed by genetic axonal labeling of transient receptor potential melastatin 8 neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 14147-57. PMID 18094254 DOI: 10.1523/JNEUROSCI.4578-07.2007  0.795
2007 Daniels RL, McKemy DD. Mice left out in the cold: commentary on the phenotype of TRPM8-nulls. Molecular Pain. 3: 23. PMID 17705869 DOI: 10.1186/1744-8069-3-23  0.737
2007 McKemy DD. Temperature sensing across species. Pflã¼Gers Archiv : European Journal of Physiology. 454: 777-91. PMID 17219191 DOI: 10.1007/s00424-006-0199-6  0.426
2005 McKemy DD. How cold is it? TRPM8 and TRPA1 in the molecular logic of cold sensation. Molecular Pain. 1: 16. PMID 15847696 DOI: 10.1186/1744-8069-1-16  0.627
2004 Jordt SE, Bautista DM, Chuang HH, McKemy DD, Zygmunt PM, Högestätt ED, Meng ID, Julius D. Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature. 427: 260-5. PMID 14712238 DOI: 10.1038/Nature02282  0.797
2003 Jordt SE, McKemy DD, Julius D. Lessons from peppers and peppermint: the molecular logic of thermosensation. Current Opinion in Neurobiology. 13: 487-92. PMID 12965298 DOI: 10.1016/S0959-4388(03)00101-6  0.831
2003 Kataoka H, Hamilton JR, McKemy DD, Camerer E, Zheng YW, Cheng A, Griffin C, Coughlin SR. Protease-activated receptors 1 and 4 mediate thrombin signaling in endothelial cells. Blood. 102: 3224-31. PMID 12869501 DOI: 10.1182/Blood-2003-04-1130  0.308
2002 McKemy DD, Neuhausser WM, Julius D. Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature. 416: 52-8. PMID 11882888 DOI: 10.1038/Nature719  0.829
2001 McNamara N, Khong A, McKemy D, Caterina M, Boyer J, Julius D, Basbaum C. ATP transduces signals from ASGM1, a glycolipid that functions as a bacterial receptor. Proceedings of the National Academy of Sciences of the United States of America. 98: 9086-91. PMID 11481474 DOI: 10.1073/pnas.161290898  0.677
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