Alaa El-Din El-Husseini - Publications

Psychiatry University of British Columbia, Vancouver, Vancouver, BC, Canada 
Synapse development

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Keith DJ, Sanderson JL, Gibson ES, Woolfrey KM, Robertson HR, Olszewski K, Kang R, El-Husseini A, Dell'acqua ML. Palmitoylation of A-kinase anchoring protein 79/150 regulates dendritic endosomal targeting and synaptic plasticity mechanisms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 7119-36. PMID 22623657 DOI: 10.1523/Jneurosci.0784-12.2012  0.555
2011 Huang K, Sanders SS, Kang R, Carroll JB, Sutton L, Wan J, Singaraja R, Young FB, Liu L, El-Husseini A, Davis NG, Hayden MR. Wild-type HTT modulates the enzymatic activity of the neuronal palmitoyl transferase HIP14. Human Molecular Genetics. 20: 3356-65. PMID 21636527 DOI: 10.1093/Hmg/Ddr242  0.406
2011 Arstikaitis P, Gauthier-Campbell C, Huang K, El-Husseini A, Murphy TH. Proteins that promote filopodia stability, but not number, lead to more axonal-dendritic contacts. Plos One. 6: e16998. PMID 21408225 DOI: 10.1371/Journal.Pone.0016998  0.462
2010 Joiner ML, Lisé MF, Yuen EY, Kam AY, Zhang M, Hall DD, Malik ZA, Qian H, Chen Y, Ulrich JD, Burette AC, Weinberg RJ, Law PY, El-Husseini A, Yan Z, et al. Assembly of a beta2-adrenergic receptor--GluR1 signalling complex for localized cAMP signalling. The Embo Journal. 29: 482-95. PMID 19942860 DOI: 10.1038/Emboj.2009.344  0.329
2010 Dahlhaus R, El-Husseini A. Altered neuroligin expression is involved in social deficits in a mouse model of the fragile X syndrome Behavioural Brain Research. 208: 96-105. PMID 19932134 DOI: 10.1016/J.Bbr.2009.11.019  0.393
2010 Levinson JN, Li R, Kang R, Moukhles H, El-Husseini A, Bamji SX. Postsynaptic scaffolding molecules modulate the localization of neuroligins. Neuroscience. 165: 782-93. PMID 19914352 DOI: 10.1016/J.Neuroscience.2009.11.016  0.547
2010 Lui L, Levinson JN, Noël G, Handrigan GR, Richman JM, El-Husseini A, Moukhles H. Synaptic localization of neuroligin 2 in the rodent retina: comparative study with the dystroglycan-containing complex. Journal of Neuroscience Research. 88: 837-49. PMID 19859968 DOI: 10.1002/Jnr.22258  0.407
2010 Dahlhaus R, Hines RM, Eadie BD, Kannangara TS, Hines DJ, Brown CE, Christie BR, El-Husseini A. Overexpression of the cell adhesion protein neuroligin-1 induces learning deficits and impairs synaptic plasticity by altering the ratio of excitation to inhibition in the hippocampus. Hippocampus. 20: 305-22. PMID 19437420 DOI: 10.1002/Hipo.20630  0.745
2009 Gutiérrez RC, Flynn R, Hung J, Kertesz AC, Sullivan A, Zamponi GW, El-Husseini A, Colicos MA. Activity-driven mobilization of post-synaptic proteins. The European Journal of Neuroscience. 30: 2042-52. PMID 20128843 DOI: 10.1111/J.1460-9568.2009.07007.X  0.448
2009 Lisé MF, Srivastava DP, Arstikaitis P, Lett RL, Sheta R, Viswanathan V, Penzes P, O'Connor TP, El-Husseini A. Myosin-Va-interacting protein, RILPL2, controls cell shape and neuronal morphogenesis via Rac signaling. Journal of Cell Science. 122: 3810-21. PMID 19812310 DOI: 10.1242/Jcs.050344  0.433
2009 Huang K, Sanders S, Singaraja R, Orban P, Cijsouw T, Arstikaitis P, Yanai A, Hayden MR, El-Husseini A. Neuronal palmitoyl acyl transferases exhibit distinct substrate specificity Faseb Journal. 23: 2605-2615. PMID 19299482 DOI: 10.1096/Fj.08-127399  0.336
2008 Kang R, Wan J, Arstikaitis P, Takahashi H, Huang K, Bailey AO, Thompson JX, Roth AF, Drisdel RC, Mastro R, Green WN, Yates JR, Davis NG, El-Husseini A. Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation. Nature. 456: 904-9. PMID 19092927 DOI: 10.1038/Nature07605  0.525
2008 Keith D, El-Husseini A. Excitation Control: Balancing PSD-95 Function at the Synapse. Frontiers in Molecular Neuroscience. 1: 4. PMID 18946537 DOI: 10.3389/neuro.02.004.2008  0.444
2008 Krivosheya D, Tapia L, Levinson JN, Huang K, Kang Y, Hines R, Ting AK, Craig AM, Mei L, Bamji SX, El-Husseini A. ErbB4-neuregulin signaling modulates synapse development and dendritic arborization through distinct mechanisms. The Journal of Biological Chemistry. 283: 32944-56. PMID 18819924 DOI: 10.1074/Jbc.M800073200  0.752
2008 Hines RM, Wu L, Hines DJ, Steenland H, Mansour S, Dahlhaus R, Singaraja RR, Cao X, Sammler E, Hormuzdi SG, Zhuo M, El-Husseini A. Synaptic imbalance, stereotypies, and impaired social interactions in mice with altered neuroligin 2 expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6055-67. PMID 18550748 DOI: 10.1523/Jneurosci.0032-08.2008  0.723
2008 Sornarajah L, Vasuta OC, Zhang L, Sutton C, Li B, El-Husseini A, Raymond LA. NMDA receptor desensitization regulated by direct binding to PDZ1-2 domains of PSD-95. Journal of Neurophysiology. 99: 3052-62. PMID 18400955 DOI: 10.1152/Jn.90301.2008  0.516
2008 Correia SS, Bassani S, Brown TC, Lisé MF, Backos DS, El-Husseini A, Passafaro M, Esteban JA. Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation. Nature Neuroscience. 11: 457-66. PMID 18311135 DOI: 10.1038/Nn2063  0.504
2008 Arstikaitis P, Gauthier-Campbell C, Carolina Gutierrez Herrera R, Huang K, Levinson JN, Murphy TH, Kilimann MW, Sala C, Colicos MA, El-Husseini A. Paralemmin-1, a modulator of filopodia induction is required for spine maturation. Molecular Biology of the Cell. 19: 2026-38. PMID 18287537 DOI: 10.1091/Mbc.E07-08-0802  0.509
2008 Keith D, El-Husseini A. Excitation control: Balancing PSD-95 function at the synapse Frontiers in Molecular Neuroscience. 1. DOI: 10.3389/Neuro.02.004.2008  0.531
2007 Levinson JN, El-Husseini A. A crystal-clear interaction: relating neuroligin/neurexin complex structure to function at the synapse. Neuron. 56: 937-9. PMID 18093514 DOI: 10.1016/J.Neuron.2007.12.003  0.4
2007 Gerrow K, El-Husseini A. Receptors look outward: revealing signals that bring excitation to synapses Science's Stke : Signal Transduction Knowledge Environment. 2007: pe56. PMID 17940274 DOI: 10.1126/Stke.4082007Pe56  0.525
2007 Goytain A, Hines RM, El-Husseini A, Quamme GA. NIPA1(SPG6), the basis for autosomal dominant form of hereditary spastic paraplegia, encodes a functional Mg2+ transporter. The Journal of Biological Chemistry. 282: 8060-8. PMID 17166836 DOI: 10.1074/Jbc.M610314200  0.678
2007 El-Husseini A. Modulation of excitatory synapse maturation by assembly of a postsynaptic protein complex containing PSD-95 and neuroligins Neuroscience Research. 58: S11. DOI: 10.1016/J.Neures.2007.06.063  0.487
2006 Bi GQ, Bolshakov V, Bu G, Cahill CM, Chen ZF, Collingridge GL, Cooper RL, Coorssen JR, El-Husseini A, Galhardo V, Gan WB, Gu J, Inoue K, Isaac J, Iwata K, et al. Recent advances in basic neurosciences and brain disease: from synapses to behavior. Molecular Pain. 2: 38. PMID 17196111 DOI: 10.1186/1744-8069-2-38  0.337
2006 Lisé MF, El-Husseini A. The neuroligin and neurexin families: From structure to function at the synapse Cellular and Molecular Life Sciences. 63: 1833-1849. PMID 16794786 DOI: 10.1007/s00018-006-6061-3  0.391
2006 Devon RS, Orban PC, Gerrow K, Barbieri MA, Schwab C, Cao LP, Helm JR, Bissada N, Cruz-Aguado R, Davidson TL, Witmer J, Metzler M, Lam CK, Tetzlaff W, Simpson EM, ... ... El-Husseini AE, et al. Als2-deficient mice exhibit disturbances in endosome trafficking associated with motor behavioral abnormalities. Proceedings of the National Academy of Sciences of the United States of America. 103: 9595-600. PMID 16769894 DOI: 10.1073/Pnas.0510197103  0.333
2006 Gerrow K, El-Husseini A. Cell adhesion molecules at the synapse Frontiers in Bioscience. 11: 2400-2419. PMID 16720322 DOI: 10.2741/1978  0.518
2006 Yanai A, Huang K, Kang R, Singaraja RR, Arstikaitis P, Gan L, Orban PC, Mullard A, Cowan CM, Raymond LA, Drisdel RC, Green WN, Ravikumar B, Rubinsztein DC, El-Husseini A, et al. Palmitoylation of huntingtin by HIP14 is essential for its trafficking and function. Nature Neuroscience. 9: 824-31. PMID 16699508 DOI: 10.1038/Nn1702  0.385
2006 Lai AY, Swayze RD, El-Husseini A, Song C. Interleukin-1 beta modulates AMPA receptor expression and phosphorylation in hippocampal neurons Journal of Neuroimmunology. 175: 97-106. PMID 16626814 DOI: 10.1016/J.Jneuroim.2006.03.001  0.301
2006 Gerrow K, Romorini S, Nabi SM, Colicos MA, Sala C, El-Husseini A. A preformed complex of postsynaptic proteins is involved in excitatory synapse development. Neuron. 49: 547-62. PMID 16476664 DOI: 10.1016/j.neuron.2006.01.015  0.506
2006 Lisé MF, Wong TP, Trinh A, Hines RM, Liu L, Kang R, Hines DJ, Lu J, Goldenring JR, Wang YT, El-Husseini A. Involvement of myosin Vb in glutamate receptor trafficking. The Journal of Biological Chemistry. 281: 3669-78. PMID 16338934 DOI: 10.1074/Jbc.M511725200  0.724
2006 Hines RM, El-Husseini A. Mechanisms that regulate neuronal protein clustering at the synapse Molecular Mechanisms of Synaptogenesis. 67-80. DOI: 10.1007/978-0-387-32562-0_5  0.722
2005 Levinson JN, El-Husseini A. Building excitatory and inhibitory synapses: balancing neuroligin partnerships. Neuron. 48: 171-4. PMID 16242398 DOI: 10.1016/J.Neuron.2005.09.017  0.476
2005 Huang K, El-Husseini A. Modulation of neuronal protein trafficking and function by palmitoylation Current Opinion in Neurobiology. 15: 527-535. PMID 16125924 DOI: 10.1016/J.Conb.2005.08.001  0.568
2005 Levinson JN, El-Husseini A. New players tip the scales in the balance between excitatory and inhibitory synapses. Molecular Pain. 1: 12. PMID 15813960 DOI: 10.1186/1744-8069-1-12  0.551
2005 Levinson JN, Chéry N, Huang K, Wong TP, Gerrow K, Kang R, Prange O, Wang YT, El-Husseini A. Neuroligins mediate excitatory and inhibitory synapse formation: involvement of PSD-95 and neurexin-1beta in neuroligin-induced synaptic specificity. The Journal of Biological Chemistry. 280: 17312-9. PMID 15723836 DOI: 10.1074/Jbc.M413812200  0.526
2004 Huang K, Yanai A, Kang R, Arstikaitis P, Singaraja RR, Metzler M, Mullard A, Haigh B, Gauthier-Campbell C, Gutekunst CA, Hayden MR, El-Husseini A. Huntingtin-interacting protein HIP14 is a palmitoyl transferase involved in palmitoylation and trafficking of multiple neuronal proteins. Neuron. 44: 977-86. PMID 15603740 DOI: 10.1016/J.Neuron.2004.11.027  0.469
2004 Washbourne P, Dityatev A, Scheiffele P, Biederer T, Weiner JA, Christopherson KS, El-Husseini A. Cell adhesion molecules in synapse formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9244-9. PMID 15496659 DOI: 10.1523/Jneurosci.3339-04.2004  0.496
2004 Swayze RD, Lisé MF, Levinson JN, Phillips A, El-Husseini A. Modulation of dopamine mediated phosphorylation of AMPA receptors by PSD-95 and AKAP79/150. Neuropharmacology. 47: 764-78. PMID 15458848 DOI: 10.1016/J.Neuropharm.2004.07.014  0.39
2004 Prange O, Wong TP, Gerrow K, Wang YT, El-Husseini A. A balance between excitatory and inhibitory synapses is controlled by PSD-95 and neuroligin. Proceedings of the National Academy of Sciences of the United States of America. 101: 13915-20. PMID 15358863 DOI: 10.1073/Pnas.0405939101  0.504
2004 Kang R, Swayze R, Lise MF, Gerrow K, Mullard A, Honer WG, El-Husseini A. Presynaptic trafficking of synaptotagmin I is regulated by protein palmitoylation. The Journal of Biological Chemistry. 279: 50524-36. PMID 15355980 DOI: 10.1074/Jbc.M404981200  0.526
2003 Chen L, El-Husseini A, Tomita S, Bredt DS, Nicoll RA. Stargazin differentially controls the trafficking of alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionate and kainate receptors. Molecular Pharmacology. 64: 703-6. PMID 12920207 DOI: 10.1124/Mol.64.3.703  0.682
2001 El-Husseini AE, Fretier P, Vincent SR. Cloning and characterization of a gene (RNF22) encoding a novel brain expressed ring finger protein (BERP) that maps to human chromosome 11p15.5. Genomics. 71: 363-7. PMID 11170753 DOI: 10.1006/Geno.2000.6452  0.553
2000 El-Husseini AE, Schnell E, Chetkovich DM, Nicoll RA, Bredt DS. PSD-95 involvement in maturation of excitatory synapses. Science (New York, N.Y.). 290: 1364-8. PMID 11082065 DOI: 10.1126/Science.290.5495.1364  0.778
2000 El-Husseini AE, Topinka JR, Lehrer-Graiwer JE, Firestein BL, Craven SE, Aoki C, Bredt DS. Ion channel clustering by membrane-associated guanylate kinases. Differential regulation by N-terminal lipid and metal binding motifs. The Journal of Biological Chemistry. 275: 23904-10. PMID 10779526 DOI: 10.1074/Jbc.M909919199  0.731
2000 El-Husseini AE, Kwasnicka D, Yamada T, Hirohashi S, Vincent SR. BERP, a novel ring finger protein, binds to alpha-actinin-4. Biochemical and Biophysical Research Communications. 267: 906-11. PMID 10673389 DOI: 10.1006/Bbrc.1999.2045  0.581
2000 El-Husseini AE, Craven SE, Chetkovich DM, Firestein BL, Schnell E, Aoki C, Bredt DS. Dual palmitoylation of PSD-95 mediates its vesiculotubular sorting, postsynaptic targeting, and ion channel clustering. The Journal of Cell Biology. 148: 159-72. PMID 10629226 DOI: 10.1083/Jcb.148.1.159  0.748
1999 Firestein BL, Firestein BL, Brenman JE, Aoki C, Sanchez-Perez AM, El-Husseini AE, Bredt DS. Cypin: a cytosolic regulator of PSD-95 postsynaptic targeting. Neuron. 24: 659-72. PMID 10595517 DOI: 10.1016/S0896-6273(00)81120-4  0.775
1999 El-Husseini AE, Williams J, Reiner PB, Pelech S, Vincent SR. Localization of the cGMP-dependent protein kinases in relation to nitric oxide synthase in the brain. Journal of Chemical Neuroanatomy. 17: 45-55. PMID 10569239 DOI: 10.1016/S0891-0618(99)00023-X  0.561
1999 El-Husseini AE, Vincent SR. Cloning and characterization of a novel RING finger protein that interacts with class V myosins. The Journal of Biological Chemistry. 274: 19771-7. PMID 10391919 DOI: 10.1074/Jbc.274.28.19771  0.585
1999 Craven SE, El-Husseini AE, Bredt DS. Synaptic targeting of the postsynaptic density protein PSD-95 mediated by lipid and protein motifs. Neuron. 22: 497-509. PMID 10197530 DOI: 10.1016/S0896-6273(00)80705-9  0.694
1998 El-Husseini AE, Bladen C, Williams JA, Reiner PB, Vincent SR. Nitric oxide regulates cyclic GMP-dependent protein kinase phosphorylation in rat brain. Journal of Neurochemistry. 71: 676-83. PMID 9681458 DOI: 10.1046/J.1471-4159.1998.71020676.X  0.54
1997 El-Husseini AE, Guthrie H, Snutch TP, Vincent SR. Molecular cloning of a mammalian homologue of the yeast vesicular transport protein vps45. Biochimica Et Biophysica Acta. 1325: 8-12. PMID 9106478 DOI: 10.1016/S0005-2736(97)00014-X  0.616
1995 el-Husseini AE, Bladen C, Vincent SR. Molecular characterization of a type II cyclic GMP-dependent protein kinase expressed in the rat brain. Journal of Neurochemistry. 64: 2814-7. PMID 7760063 DOI: 10.1046/J.1471-4159.1995.64062814.X  0.519
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