John T. Isaac - Publications

National Institutes of Health, Bethesda, MD 
Synaptic plasticity; synaptic function; hippocampus; barrel cortex; AMPAR; kianate receptor

86 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Petrus E, Dembling S, Usdin T, Isaac JT, Koretsky AP. Circuit Specific Plasticity of Callosal Inputs Underlies Cortical Takeover. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32913109 DOI: 10.1523/Jneurosci.1056-20.2020  0.372
2017 Jackson JS, Witton J, Johnson JD, Ahmed Z, Ward M, Randall AD, Hutton ML, Isaac JT, O'Neill MJ, Ashby MC. Altered Synapse Stability in the Early Stages of Tauopathy. Cell Reports. 18: 3063-3068. PMID 28355559 DOI: 10.1016/J.Celrep.2017.03.013  0.838
2017 Jackson J, Tamagnini F, Johnson J, Stephen T, Ahmed Z, Oliver-Evans A, Meftah S, Hutton ML, Isaac J, Randall A, Ashby M, O'Neill MJ. In Vivo Two-Photon Imaging Of The Effects Of Tauopathy And Amyloidopathy On Synapses Alzheimers & Dementia. 13: 1002. DOI: 10.1016/J.Jalz.2017.06.1390  0.791
2016 Kato AS, Burris KD, Gardinier KM, Gernert DL, Porter WJ, Reel J, Ding C, Tu Y, Schober DA, Lee MR, Heinz BA, Fitch TE, Gleason SD, Catlow JT, Yu H, ... ... Isaac JT, et al. Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism. Nature Medicine. PMID 27820603 DOI: 10.1038/Nm.4221  0.821
2015 Dennis SH, Pasqui F, Colvin EM, Sanger H, Mogg AJ, Felder CC, Broad LM, Fitzjohn SM, Isaac JT, Mellor JR. Activation of Muscarinic M1 Acetylcholine Receptors Induces Long-Term Potentiation in the Hippocampus. Cerebral Cortex (New York, N.Y. : 1991). PMID 26472558 DOI: 10.1093/Cercor/Bhv227  0.863
2015 Crocker-Buque A, Brown SM, Kind PC, Isaac JT, Daw MI. Experience-Dependent, Layer-Specific Development of Divergent Thalamocortical Connectivity. Cerebral Cortex (New York, N.Y. : 1991). 25: 2255-66. PMID 24610243 DOI: 10.1093/Cercor/Bhu031  0.768
2014 Dage JL, Colvin EM, Fouillet A, Langron E, Roell WC, Li J, Mathur SX, Mogg AJ, Schmitt MG, Felder CC, Merchant KM, Isaac J, Broad LM, Sher E, Ursu D. Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons. Psychopharmacology. 231: 1105-24. PMID 24429870 DOI: 10.1007/S00213-013-3384-2  0.384
2014 Morita D, Rah JC, Isaac JT. Incorporation of inwardly rectifying AMPA receptors at silent synapses during hippocampal long-term potentiation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369: 20130156. PMID 24298157 DOI: 10.1098/rstb.2013.0156  0.795
2014 Jackson J, Johnson J, Ahmed Z, Ward M, Hutton M, Ashby M, Isaac J, O'Neill M. In Vivo Two-Photon Imaging Of Progressive Synapse Loss And Altered Spine Dynamics In The Rtg4510 Tauopathy Model Alzheimers & Dementia. 10: 29. DOI: 10.1016/J.Jalz.2014.05.054  0.76
2013 Rah JC, Bas E, Colonell J, Mishchenko Y, Karsh B, Fetter RD, Myers EW, Chklovskii DB, Svoboda K, Harris TD, Isaac JT. Thalamocortical input onto layer 5 pyramidal neurons measured using quantitative large-scale array tomography. Frontiers in Neural Circuits. 7: 177. PMID 24273494 DOI: 10.3389/Fncir.2013.00177  0.717
2013 Crabtree JW, Lodge D, Bashir ZI, Isaac JT. GABAA , NMDA and mGlu2 receptors tonically regulate inhibition and excitation in the thalamic reticular nucleus. The European Journal of Neuroscience. 37: 850-9. PMID 23294136 DOI: 10.1111/ejn.12098  0.742
2012 Kato AS, Knierman MD, Siuda ER, Isaac JT, Nisenbaum ES, Bredt DS. Glutamate receptor δ2 associates with metabotropic glutamate receptor 1 (mGluR1), protein kinase Cγ, and canonical transient receptor potential 3 and regulates mGluR1-mediated synaptic transmission in cerebellar Purkinje neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15296-308. PMID 23115168 DOI: 10.1523/Jneurosci.0705-12.2012  0.508
2012 Yu X, Chung S, Chen DY, Wang S, Dodd SJ, Walters JR, Isaac JT, Koretsky AP. Thalamocortical inputs show post-critical-period plasticity. Neuron. 74: 731-42. PMID 22632730 DOI: 10.1016/J.Neuron.2012.04.024  0.69
2011 Ashby MC, Isaac JT. Maturation of a recurrent excitatory neocortical circuit by experience-dependent unsilencing of newly formed dendritic spines. Neuron. 70: 510-21. PMID 21555076 DOI: 10.1016/J.Neuron.2011.02.057  0.735
2011 Matta JA, Ashby MC, Sanz-Clemente A, Roche KW, Isaac JT. mGluR5 and NMDA receptors drive the experience- and activity-dependent NMDA receptor NR2B to NR2A subunit switch. Neuron. 70: 339-51. PMID 21521618 DOI: 10.1016/J.Neuron.2011.02.045  0.836
2011 Bortolotto ZA, Amici M, Anderson WW, Isaac JT, Collingridge GL. Synaptic plasticity in the hippocampal slice preparation. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 6.13. PMID 21207366 DOI: 10.1002/0471142301.ns0613s54  0.814
2011 Jouhanneau JS, Ball SM, Molnár E, Isaac JT. Mechanisms of bi-directional modulation of thalamocortical transmission in barrel cortex by presynaptic kainate receptors. Neuropharmacology. 60: 832-41. PMID 21187105 DOI: 10.1016/J.Neuropharm.2010.12.023  0.862
2010 Brown JT, Weatherall KL, Corria LR, Chater TE, Isaac JT, Marrion NV. Vesicular release of glutamate utilizes the proton gradient between the vesicle and synaptic cleft. Frontiers in Synaptic Neuroscience. 2: 15. PMID 21423501 DOI: 10.3389/fnsyn.2010.00015  0.583
2010 Chittajallu R, Isaac JT. Emergence of cortical inhibition by coordinated sensory-driven plasticity at distinct synaptic loci. Nature Neuroscience. 13: 1240-8. PMID 20871602 DOI: 10.1038/nn.2639  0.834
2010 Sanz-Clemente A, Matta JA, Isaac JT, Roche KW. Casein kinase 2 regulates the NR2 subunit composition of synaptic NMDA receptors. Neuron. 67: 984-96. PMID 20869595 DOI: 10.1016/J.Neuron.2010.08.011  0.832
2010 Evers DM, Matta JA, Hoe HS, Zarkowsky D, Lee SH, Isaac JT, Pak DT. Plk2 attachment to NSF induces homeostatic removal of GluA2 during chronic overexcitation. Nature Neuroscience. 13: 1199-207. PMID 20802490 DOI: 10.1038/Nn.2624  0.834
2010 Suh YH, Terashima A, Petralia RS, Wenthold RJ, Isaac JT, Roche KW, Roche PA. A neuronal role for SNAP-23 in postsynaptic glutamate receptor trafficking. Nature Neuroscience. 13: 338-43. PMID 20118925 DOI: 10.1038/nn.2488  0.656
2010 Nasu-Nishimura Y, Jaffe H, Isaac JT, Roche KW. Differential regulation of kainate receptor trafficking by phosphorylation of distinct sites on GluR6. The Journal of Biological Chemistry. 285: 2847-56. PMID 19920140 DOI: 10.1074/jbc.M109.081141  0.457
2009 Walker CS, Jensen S, Ellison M, Matta JA, Lee WY, Imperial JS, Duclos N, Brockie PJ, Madsen DM, Isaac JT, Olivera B, Maricq AV. A novel Conus snail polypeptide causes excitotoxicity by blocking desensitization of AMPA receptors. Current Biology : Cb. 19: 900-8. PMID 19481459 DOI: 10.1016/J.Cub.2009.05.017  0.786
2009 Isaac JT, Buchanan KA, Muller RU, Mellor JR. Hippocampal place cell firing patterns can induce long-term synaptic plasticity in vitro. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6840-50. PMID 19474311 DOI: 10.1523/JNEUROSCI.0731-09.2009  0.498
2009 Lüscher C, Isaac JT. The synapse: center stage for many brain diseases. The Journal of Physiology. 587: 727-9. PMID 19074963 DOI: 10.1113/jphysiol.2008.167742  0.5
2008 Mistry RB, Isaac JT, Crabtree JW. Two differential frequency-dependent mechanisms regulating tonic firing of thalamic reticular neurons. The European Journal of Neuroscience. 27: 2643-56. PMID 18547248 DOI: 10.1111/j.1460-9568.2008.06246.x  0.343
2008 Terashima A, Pelkey KA, Rah JC, Suh YH, Roche KW, Collingridge GL, McBain CJ, Isaac JT. An essential role for PICK1 in NMDA receptor-dependent bidirectional synaptic plasticity. Neuron. 57: 872-82. PMID 18367088 DOI: 10.1016/j.neuron.2008.01.028  0.88
2007 Daw M, Isaac J. Electrophysiological recordings from neonatal neocortical brain slices Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 6.23. PMID 18428662 DOI: 10.1002/0471142301.Ns0623S38  0.764
2007 Isaac JT, Ashby MC, McBain CJ. The role of the GluR2 subunit in AMPA receptor function and synaptic plasticity. Neuron. 54: 859-71. PMID 17582328 DOI: 10.1016/J.Neuron.2007.06.001  0.851
2007 Daw MI, Ashby MC, Isaac JT. Coordinated developmental recruitment of latent fast spiking interneurons in layer IV barrel cortex. Nature Neuroscience. 10: 453-61. PMID 17351636 DOI: 10.1038/Nn1866  0.808
2007 Peineau S, Taghibiglou C, Bradley C, Wong TP, Liu L, Lu J, Lo E, Wu D, Saule E, Bouschet T, Matthews P, Isaac JT, Bortolotto ZA, Wang YT, Collingridge GL. LTP inhibits LTD in the hippocampus via regulation of GSK3beta. Neuron. 53: 703-17. PMID 17329210 DOI: 10.1016/J.Neuron.2007.01.029  0.829
2007 Daw MI, Scott HL, Isaac JT. Developmental synaptic plasticity at the thalamocortical input to barrel cortex: mechanisms and roles. Molecular and Cellular Neurosciences. 34: 493-502. PMID 17329121 DOI: 10.1016/J.Mcn.2007.01.001  0.847
2007 Scott HL, Braud S, Bannister NJ, Isaac JT. Synaptic strength at the thalamocortical input to layer IV neonatal barrel cortex is regulated by protein kinase C. Neuropharmacology. 52: 185-92. PMID 16890249 DOI: 10.1016/j.neuropharm.2006.06.016  0.825
2006 Bi GQ, Bolshakov V, Bu G, Cahill CM, Chen ZF, Collingridge GL, Cooper RL, Coorssen JR, El-Husseini A, Galhardo V, Gan WB, Gu J, Inoue K, Isaac J, Iwata K, et al. Recent advances in basic neurosciences and brain disease: from synapses to behavior. Molecular Pain. 2: 38. PMID 17196111 DOI: 10.1186/1744-8069-2-38  0.643
2006 Nasu-Nishimura Y, Hurtado D, Braud S, Tang TT, Isaac JT, Roche KW. Identification of an endoplasmic reticulum-retention motif in an intracellular loop of the kainate receptor subunit KA2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 7014-21. PMID 16807331 DOI: 10.1523/Jneurosci.0573-06.2006  0.724
2006 Lauri SE, Vesikansa A, SegerstrÃ¥le M, Collingridge GL, Isaac JT, Taira T. Functional maturation of CA1 synapses involves activity-dependent loss of tonic kainate receptor-mediated inhibition of glutamate release. Neuron. 50: 415-29. PMID 16675396 DOI: 10.1016/j.neuron.2006.03.020  0.736
2006 Daw MI, Bannister NV, Isaac JT. Rapid, activity-dependent plasticity in timing precision in neonatal barrel cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4178-87. PMID 16624938 DOI: 10.1523/Jneurosci.0150-06.2006  0.838
2006 Chen BS, Braud S, Badger JD, Isaac JT, Roche KW. Regulation of NR1/NR2C N-methyl-D-aspartate (NMDA) receptors by phosphorylation. The Journal of Biological Chemistry. 281: 16583-90. PMID 16606616 DOI: 10.1074/jbc.M513029200  0.751
2006 Plant K, Pelkey KA, Bortolotto ZA, Morita D, Terashima A, McBain CJ, Collingridge GL, Isaac JT. Transient incorporation of native GluR2-lacking AMPA receptors during hippocampal long-term potentiation. Nature Neuroscience. 9: 602-4. PMID 16582904 DOI: 10.1038/nn1678  0.856
2006 Park Y, Jo J, Isaac JT, Cho K. Long-term depression of kainate receptor-mediated synaptic transmission. Neuron. 49: 95-106. PMID 16387642 DOI: 10.1016/j.neuron.2005.11.035  0.459
2005 Palmer CL, Lim W, Hastie PG, Toward M, Korolchuk VI, Burbidge SA, Banting G, Collingridge GL, Isaac JT, Henley JM. Hippocalcin functions as a calcium sensor in hippocampal LTD. Neuron. 47: 487-94. PMID 16102532 DOI: 10.1016/J.Neuron.2005.06.014  0.719
2005 Maingret F, Lauri SE, Taira T, Isaac JT. Profound regulation of neonatal CA1 rat hippocampal GABAergic transmission by functionally distinct kainate receptor populations. The Journal of Physiology. 567: 131-42. PMID 15946969 DOI: 10.1113/jphysiol.2005.089474  0.472
2005 Bannister NJ, Benke TA, Mellor J, Scott H, Gürdal E, Crabtree JW, Isaac JT. Developmental changes in AMPA and kainate receptor-mediated quantal transmission at thalamocortical synapses in the barrel cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5259-71. PMID 15917466 DOI: 10.1523/Jneurosci.0827-05.2005  0.844
2005 Kim CH, Braud S, Isaac JT, Roche KW. Protein kinase C phosphorylation of the metabotropic glutamate receptor mGluR5 on Serine 839 regulates Ca2+ oscillations. The Journal of Biological Chemistry. 280: 25409-15. PMID 15894802 DOI: 10.1074/jbc.M502644200  0.718
2005 Lauri SE, SegerstrÃ¥le M, Vesikansa A, Maingret F, Mulle C, Collingridge GL, Isaac JT, Taira T. Endogenous activation of kainate receptors regulates glutamate release and network activity in the developing hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4473-84. PMID 15872094 DOI: 10.1523/Jneurosci.4050-04.2005  0.754
2005 Lim W, Isaac JT. ATP hydrolysis is required for the rapid regulation of AMPA receptors during basal synaptic transmission and long-term synaptic plasticity. Neuropharmacology. 48: 949-55. PMID 15857621 DOI: 10.1016/j.neuropharm.2005.02.001  0.559
2004 Isaac JT, Mellor J, Hurtado D, Roche KW. Kainate receptor trafficking: physiological roles and molecular mechanisms. Pharmacology & Therapeutics. 104: 163-72. PMID 15556673 DOI: 10.1016/J.Pharmthera.2004.08.006  0.433
2004 Collingridge GL, Isaac JT, Wang YT. Receptor trafficking and synaptic plasticity. Nature Reviews. Neuroscience. 5: 952-62. PMID 15550950 DOI: 10.1038/nrn1556  0.724
2004 Lüthi A, Wikström MA, Palmer MJ, Matthews P, Benke TA, Isaac JT, Collingridge GL. Bi-directional modulation of AMPA receptor unitary conductance by synaptic activity. Bmc Neuroscience. 5: 44. PMID 15538948 DOI: 10.1186/1471-2202-5-44  0.873
2004 Terashima A, Cotton L, Dev KK, Meyer G, Zaman S, Duprat F, Henley JM, Collingridge GL, Isaac JT. Regulation of synaptic strength and AMPA receptor subunit composition by PICK1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5381-90. PMID 15190111 DOI: 10.1523/Jneurosci.4378-03.2004  0.8
2004 Palmer MJ, Isaac JT, Collingridge GL. Multiple, developmentally regulated expression mechanisms of long-term potentiation at CA1 synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4903-11. PMID 15163681 DOI: 10.1523/Jneurosci.0170-04.2004  0.84
2003 Hayes DM, Braud S, Hurtado DE, McCallum J, Standley S, Isaac JT, Roche KW. Trafficking and surface expression of the glutamate receptor subunit, KA2. Biochemical and Biophysical Research Communications. 310: 8-13. PMID 14511640 DOI: 10.1016/j.bbrc.2003.08.115  0.744
2003 Collingridge GL, Isaac JT. Functional roles of protein interactions with AMPA and kainate receptors. Neuroscience Research. 47: 3-15. PMID 12941441 DOI: 10.1016/S0168-0102(03)00160-3  0.777
2003 Isaac JT. Postsynaptic silent synapses: evidence and mechanisms. Neuropharmacology. 45: 450-60. PMID 12907306 DOI: 10.1016/S0028-3908(03)00229-6  0.569
2003 Lauri SE, Bortolotto ZA, Nistico R, Bleakman D, Ornstein PL, Lodge D, Isaac JT, Collingridge GL. A role for Ca2+ stores in kainate receptor-dependent synaptic facilitation and LTP at mossy fiber synapses in the hippocampus. Neuron. 39: 327-41. PMID 12873388 DOI: 10.1016/S0896-6273(03)00369-6  0.834
2003 Duprat F, Daw M, Lim W, Collingridge G, Isaac J. GluR2 protein-protein interactions and the regulation of AMPA receptors during synaptic plasticity Philosophical Transactions of the Royal Society B: Biological Sciences. 358: 715-720. PMID 12740117 DOI: 10.1098/Rstb.2002.1215  0.874
2003 Bortolotto ZA, Lauri S, Isaac JT, Collingridge GL. Kainate receptors and the induction of mossy fibre long-term potentiation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 358: 657-66. PMID 12740111 DOI: 10.1098/rstb.2002.1216  0.83
2003 Hirbec H, Francis JC, Lauri SE, Braithwaite SP, Coussen F, Mulle C, Dev KK, Coutinho V, Meyer G, Isaac JT, Collingridge GL, Henley JM, Couthino V. Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP. Neuron. 37: 625-38. PMID 12597860 DOI: 10.1016/S0896-6273(02)01191-1  0.825
2002 Molnar E, Isaac JT. Developmental and activity dependent regulation of ionotropic glutamate receptors at synapses. Thescientificworldjournal. 2: 27-47. PMID 12806037 DOI: 10.1100/Tsw.2002.74  0.541
2002 Daw MI, Bortolotto ZA, Saulle E, Zaman S, Collingridge GL, Isaac JT. Phosphatidylinositol 3 kinase regulates synapse specificity of hippocampal long-term depression. Nature Neuroscience. 5: 835-6. PMID 12161757 DOI: 10.1038/Nn903  0.845
2002 Kidd FL, Coumis U, Collingridge GL, Crabtree JW, Isaac JT. A presynaptic kainate receptor is involved in regulating the dynamic properties of thalamocortical synapses during development. Neuron. 34: 635-46. PMID 12062046 DOI: 10.1016/S0896-6273(02)00699-2  0.763
2001 Bortolotto ZA, Anderson WW, Isaac JT, Collingridge GL. Synaptic plasticity in the hippocampal slice preparation. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 6.13. PMID 18428512 DOI: 10.1002/0471142301.ns0613s16  0.814
2001 Isaac J. Protein phosphatase 1 and LTD: Synapses are the architects of depression Neuron. 32: 963-966. PMID 11754828 DOI: 10.1016/S0896-6273(01)00545-1  0.496
2001 Benke TA, Lüthi A, Palmer MJ, Wikström MA, Anderson WW, Isaac JT, Collingridge GL. Mathematical modelling of non-stationary fluctuation analysis for studying channel properties of synaptic AMPA receptors. The Journal of Physiology. 537: 407-20. PMID 11731574 DOI: 10.1111/J.1469-7793.2001.00407.X  0.853
2001 Lauri SE, Bortolotto ZA, Bleakman D, Ornstein PL, Lodge D, Isaac JT, Collingridge GL. A critical role of a facilitatory presynaptic kainate receptor in mossy fiber LTP. Neuron. 32: 697-709. PMID 11719209 DOI: 10.1016/S0896-6273(01)00511-6  0.839
2001 Kidd FL, Isaac JT. Kinetics and activation of postsynaptic kainate receptors at thalamocortical synapses: role of glutamate clearance. Journal of Neurophysiology. 86: 1139-48. PMID 11535664  0.539
2001 Hirbec H, Lauri SE, Francis JC, Braithwaite SP, Isaac JT, Collingridge GL, Henley JM. Syntenin interacts with kainate receptors: in vitro and in vivo evidence Biochemical Society Transactions. 29: A88-A88. DOI: 10.1042/Bst029A088C  0.73
2000 Daw MI, Chittajallu R, Bortolotto ZA, Dev KK, Duprat F, Henley JM, Collingridge GL, Isaac JT. PDZ proteins interacting with C-terminal GluR2/3 are involved in a PKC-dependent regulation of AMPA receptors at hippocampal synapses. Neuron. 28: 873-86. PMID 11163273 DOI: 10.1016/S0896-6273(00)00160-4  0.812
2000 Kidd FL, Isaac JT. Glutamate transport blockade has a differential effect on AMPA and NMDA receptor-mediated synaptic transmission in the developing barrel cortex. Neuropharmacology. 39: 725-32. PMID 10699439  0.417
1999 Lüthi A, Chittajallu R, Duprat F, Palmer MJ, Benke TA, Kidd FL, Henley JM, Isaac JT, Collingridge GL. Hippocampal LTD expression involves a pool of AMPARs regulated by the NSF-GluR2 interaction. Neuron. 24: 389-99. PMID 10571232 DOI: 10.1016/S0896-6273(00)80852-1  0.847
1999 Isaac JT, Nicoll RA, Malenka RC. Silent glutamatergic synapses in the mammalian brain. Canadian Journal of Physiology and Pharmacology. 77: 735-7. PMID 10566951 DOI: 10.1139/Y99-075  0.812
1999 Kidd FL, Isaac JT. Developmental and activity-dependent regulation of kainate receptors at thalamocortical synapses. Nature. 400: 569-73. PMID 10448859 DOI: 10.1038/23040  0.549
1999 Hjelmstad GO, Isaac JT, Nicoll RA, Malenka RC. Lack of AMPA receptor desensitization during basal synaptic transmission in the hippocampal slice. Journal of Neurophysiology. 81: 3096-9. PMID 10368425 DOI: 10.1152/Jn.1999.81.6.3096  0.868
1999 Fox K, Henley J, Isaac J. Experience-dependent development of NMDA receptor transmission Nature Neuroscience. 2: 297-299. PMID 10204530 DOI: 10.1038/7203  0.675
1998 Crabtree JW, Collingridge GL, Isaac JT. A new intrathalamic pathway linking modality-related nuclei in the dorsal thalamus. Nature Neuroscience. 1: 389-94. PMID 10196529 DOI: 10.1038/1603  0.586
1998 Isaac JT, Lüthi A, Palmer MJ, Anderson WW, Benke TA, Collingridge GL. An investigation of the expression mechanism of LTP of AMPA receptor-mediated synaptic transmission at hippocampal CA1 synapses using failures analysis and dendritic recordings. Neuropharmacology. 37: 1399-410. PMID 9849675 DOI: 10.1016/S0028-3908(98)00140-3  0.866
1998 Feldman DE, Nicoll RA, Malenka RC, Isaac JT. Long-term depression at thalamocortical synapses in developing rat somatosensory cortex. Neuron. 21: 347-57. PMID 9728916 DOI: 10.1016/S0896-6273(00)80544-9  0.842
1998 Nishimune A, Isaac JT, Molnar E, Noel J, Nash SR, Tagaya M, Collingridge GL, Nakanishi S, Henley JM. NSF binding to GluR2 regulates synaptic transmission. Neuron. 21: 87-97. PMID 9697854 DOI: 10.1016/S0896-6273(00)80517-6  0.812
1998 Benke TA, Lüthi A, Isaac JT, Collingridge GL. Modulation of AMPA receptor unitary conductance by synaptic activity. Nature. 393: 793-7. PMID 9655394 DOI: 10.1038/31709  0.883
1997 Turner DA, Chen Y, Isaac JT, West M, Wheal HV. Excitatory synaptic site heterogeneity during paired pulse plasticity in CA1 pyramidal cells in rat hippocampus in vitro. The Journal of Physiology. 500: 441-61. PMID 9147329 DOI: 10.1113/Jphysiol.1997.Sp022032  0.42
1997 Isaac JT, Crair MC, Nicoll RA, Malenka RC. Silent synapses during development of thalamocortical inputs. Neuron. 18: 269-80. PMID 9052797 DOI: 10.1016/S0896-6273(00)80267-6  0.851
1996 Isaac JT, Oliet SH, Hjelmstad GO, Nicoll RA, Malenka RC. Expression mechanisms of long-term potentiation in the hippocampus. Journal of Physiology, Paris. 90: 299-303. PMID 9089495 DOI: 10.1016/S0928-4257(97)87901-6  0.848
1996 Isaac JT, Hjelmstad GO, Nicoll RA, Malenka RC. Long-term potentiation at single fiber inputs to hippocampal CA1 pyramidal cells. Proceedings of the National Academy of Sciences of the United States of America. 93: 8710-5. PMID 8710936 DOI: 10.1073/pnas.93.16.8710  0.858
1995 Isaac JT, Nicoll RA, Malenka RC. Evidence for silent synapses: implications for the expression of LTP. Neuron. 15: 427-34. PMID 7646894 DOI: 10.1016/0896-6273(95)90046-2  0.827
1993 Isaac JT, Wheal HV. The local anaesthetic QX-314 enables enhanced whole-cell recordings of excitatory synaptic currents in rat hippocampal slices in vitro. Neuroscience Letters. 150: 227-30. PMID 8385755 DOI: 10.1016/0304-3940(93)90542-S  0.694
Show low-probability matches.