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Sean B. Joseph, Ph.D. - Publications

Affiliations: 
2002 University of California, Los Angeles, Los Angeles, CA 
Area:
Molecular Biology, Cell Biology, Pathology
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Hernandez ED, Zheng L, Kim Y, Fang B, Liu B, Valdez RA, Dietrich WF, Rucker PV, Chianelli D, Schmeits J, Bao D, Zoll J, Dubois C, Federe GC, Chen L, ... Joseph SB, et al. Tropifexor-Mediated Abrogation of Steatohepatitis and Fibrosis Is Associated With the Antioxidative Gene Expression Profile in Rodents. Hepatology Communications. 3: 1085-1097. PMID 31388629 DOI: 10.1002/hep4.1368  0.314
2008 Bensinger SJ, Bradley MN, Joseph SB, Zelcer N, Janssen EM, Hausner MA, Shih R, Parks JS, Edwards PA, Jamieson BD, Tontonoz P. LXR signaling couples sterol metabolism to proliferation in the acquired immune response. Cell. 134: 97-111. PMID 18614014 DOI: 10.1016/J.Cell.2008.04.052  0.608
2007 Bradley MN, Hong C, Chen M, Joseph SB, Wilpitz DC, Wang X, Lusis AJ, Collins A, Hseuh WA, Collins JL, Tangirala RK, Tontonoz P. Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE. The Journal of Clinical Investigation. 117: 2337-46. PMID 17657314 DOI: 10.1172/Jci31909  0.718
2004 Joseph SB, Bradley MN, Castrillo A, Bruhn KW, Mak PA, Pei L, Hogenesch J, O'connell RM, Cheng G, Saez E, Miller JF, Tontonoz P. LXR-dependent gene expression is important for macrophage survival and the innate immune response. Cell. 119: 299-309. PMID 15479645 DOI: 10.1016/J.Cell.2004.09.032  0.672
2004 Walczak R, Joseph SB, Laffitte BA, Castrillo A, Pei L, Tontonoz P. Transcription of the vascular endothelial growth factor gene in macrophages is regulated by liver X receptors. The Journal of Biological Chemistry. 279: 9905-11. PMID 14699103 DOI: 10.1074/Jbc.M310587200  0.573
2004 Xu J, Chang V, Joseph SB, Trujillo C, Bassilian S, Saad MF, Lee WN, Kurland IJ. Peroxisomal proliferator-activated receptor alpha deficiency diminishes insulin-responsiveness of gluconeogenic/glycolytic/pentose gene expression and substrate cycle flux. Endocrinology. 145: 1087-95. PMID 14670991 DOI: 10.1210/En.2003-1173  0.438
2004 Xu J, Chang V, Trujillo C, Joseph SB, Vaitheesvaran B, Bassilian S, Saad M, Lee WN, Kurland IJ. 327 GLUCOSE METABOLIC COMPENSATIONS TO REDUCED ENERGY PRODUCTION FROM β-OXIDATION IN PPARα KO MOUSE. Journal of Investigative Medicine. 52: S136.5-S137. DOI: 10.1136/Jim-52-Suppl1-327  0.317
2003 Castrillo A, Joseph SB, Vaidya SA, Haberland M, Fogelman AM, Cheng G, Tontonoz P. Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism. Molecular Cell. 12: 805-16. PMID 14580333 DOI: 10.1016/S1097-2765(03)00384-8  0.67
2003 Laffitte BA, Chao LC, Li J, Walczak R, Hummasti S, Joseph SB, Castrillo A, Wilpitz DC, Mangelsdorf DJ, Collins JL, Saez E, Tontonoz P. Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue. Proceedings of the National Academy of Sciences of the United States of America. 100: 5419-24. PMID 12697904 DOI: 10.1073/Pnas.0830671100  0.689
2003 Joseph SB, Tontonoz P. LXRs: new therapeutic targets in atherosclerosis? Current Opinion in Pharmacology. 3: 192-7. PMID 12681243 DOI: 10.1016/S1471-4892(03)00009-2  0.657
2003 Laffitte BA, Joseph SB, Chen M, Castrillo A, Repa J, Wilpitz D, Mangelsdorf D, Tontonoz P. The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesions. Molecular and Cellular Biology. 23: 2182-91. PMID 12612088 DOI: 10.1128/Mcb.23.6.2182-2191.2003  0.709
2003 Castrillo A, Joseph SB, Marathe C, Mangelsdorf DJ, Tontonoz P. Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages. The Journal of Biological Chemistry. 278: 10443-9. PMID 12531895 DOI: 10.1074/Jbc.M213071200  0.675
2003 Joseph SB, Castrillo A, Laffitte BA, Mangelsdorf DJ, Tontonoz P. Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nature Medicine. 9: 213-9. PMID 12524534 DOI: 10.1038/nm820  0.65
2002 Tangirala RK, Bischoff ED, Joseph SB, Wagner BL, Walczak R, Laffitte BA, Daige CL, Thomas D, Heyman RA, Mangelsdorf DJ, Wang X, Lusis AJ, Tontonoz P, Schulman IG. Identification of macrophage liver X receptors as inhibitors of atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America. 99: 11896-901. PMID 12193651 DOI: 10.1073/Pnas.182199799  0.674
2002 Xu J, Xiao G, Trujillo C, Chang V, Blanco L, Joseph SB, Bassilian S, Saad MF, Tontonoz P, Lee WN, Kurland IJ. Peroxisome proliferator-activated receptor alpha (PPARalpha) influences substrate utilization for hepatic glucose production. The Journal of Biological Chemistry. 277: 50237-44. PMID 12176975 DOI: 10.1074/Jbc.M201208200  0.588
2002 Joseph SB, McKilligin E, Pei L, Watson MA, Collins AR, Laffitte BA, Chen M, Noh G, Goodman J, Hagger GN, Tran J, Tippin TK, Wang X, Lusis AJ, Hsueh WA, et al. Synthetic LXR ligand inhibits the development of atherosclerosis in mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 7604-9. PMID 12032330 DOI: 10.1073/Pnas.112059299  0.652
2002 Mak PA, Laffitte BA, Desrumaux C, Joseph SB, Curtiss LK, Mangelsdorf DJ, Tontonoz P, Edwards PA. Regulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages. A critical role for nuclear liver X receptors alpha and beta. The Journal of Biological Chemistry. 277: 31900-8. PMID 12032151 DOI: 10.1074/Jbc.M202993200  0.61
2002 Joseph SB, Laffitte BA, Patel PH, Watson MA, Matsukuma KE, Walczak R, Collins JL, Osborne TF, Tontonoz P. Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors. The Journal of Biological Chemistry. 277: 11019-25. PMID 11790787 DOI: 10.1074/Jbc.M111041200  0.663
2001 Laffitte BA, Joseph SB, Walczak R, Pei L, Wilpitz DC, Collins JL, Tontonoz P. Autoregulation of the human liver X receptor alpha promoter. Molecular and Cellular Biology. 21: 7558-68. PMID 11604492 DOI: 10.1128/Mcb.21.22.7558-7568.2001  0.661
2001 Lee R, Kertesz N, Joseph SB, Jegalian A, Wu H. Erythropoietin (Epo) and EpoR expression and 2 waves of erythropoiesis. Blood. 98: 1408-15. PMID 11520789 DOI: 10.1182/Blood.V98.5.1408  0.338
2001 Chawla A, Boisvert WA, Lee CH, Laffitte BA, Barak Y, Joseph SB, Liao D, Nagy L, Edwards PA, Curtiss LK, Evans RM, Tontonoz P. A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis. Molecular Cell. 7: 161-71. PMID 11172721 DOI: 10.1016/S1097-2765(01)00164-2  0.656
2001 Laffitte BA, Repa JJ, Joseph SB, Wilpitz DC, Kast HR, Mangelsdorf DJ, Tontonoz P. LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes. Proceedings of the National Academy of Sciences of the United States of America. 98: 507-12. PMID 11149950 DOI: 10.1073/pnas.021488798  0.475
2001 Laffitte BA, Repa JJ, Joseph SB, Wilpitz DC, Kast HR, Mangelsdorf DJ, Tontonoz P. LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes Proceedings of the National Academy of Sciences of the United States of America. 98: 507-512. DOI: 10.1073/Pnas.98.2.507  0.672
2000 Venkateswaran A, Laffitte BA, Joseph SB, Mak PA, Wilpitz DC, Edwards PA, Tontonoz P. Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha. Proceedings of the National Academy of Sciences of the United States of America. 97: 12097-102. PMID 11035776 DOI: 10.1073/Pnas.200367697  0.642
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