Julie Blendy - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
addiction, depression, transcription factor
Website:
http://www.med.upenn.edu/pharm/faculty/blendy/blendy.html

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Desouza LA, Benekareddy M, Fanibunda SE, Mohammad F, Janakiraman B, Ghai U, Gur T, Blendy JA, Vaidya VA. The Hallucinogenic Serotonin Receptor Agonist, 2,5-Dimethoxy-4-Iodoamphetamine, Promotes cAMP Response Element Binding Protein-Dependent Gene Expression of Specific Plasticity-Associated Genes in the Rodent Neocortex. Frontiers in Molecular Neuroscience. 14: 790213. PMID 35002622 DOI: 10.3389/fnmol.2021.790213  0.765
2020 Zhang Y, Collins D, Butelman ER, Blendy JA, Kreek MJ. Relapse-like behavior in a mouse model of the OPRM1 (mu-opioid receptor) A118G polymorphism: Examination with intravenous oxycodone self-administration. Neuropharmacology. 108351. PMID 33031806 DOI: 10.1016/j.neuropharm.2020.108351  0.304
2020 Brynildsen JK, Sanchez V, Yohn NL, Carpenter MD, Blendy JA. Sex-specific transgenerational effects of morphine exposure on reward and affective behaviors. Behavioural Brain Research. 395: 112842. PMID 32745660 DOI: 10.1016/j.bbr.2020.112842  0.776
2019 Collins D, Zhang Y, Blendy J, Kreek MJ. Murine model of OPRM1 A118G alters oxycodone self-administration and locomotor activation, but not conditioned place preference. Neuropharmacology. 107864. PMID 31778689 DOI: 10.1016/J.Neuropharm.2019.107864  0.398
2019 Manners MT, Brynildsen JK, Schechter M, Liu X, Eacret D, Blendy JA. CREB deletion increases resilience to stress and downregulates inflammatory gene expression in the hippocampus. Brain, Behavior, and Immunity. PMID 31255680 DOI: 10.1016/j.bbi.2019.06.035  0.317
2018 Yohn NL, Caruso MJ, Blendy JA. Effects of nicotine and stress exposure across generations in C57BL/6 mice. Stress (Amsterdam, Netherlands). 1-9. PMID 30457440 DOI: 10.1080/10253890.2018.1532991  0.788
2018 Manners MT, Yohn NL, Lahens NF, Grant GR, Bartolomei MS, Blendy JA. Transgenerational inheritance of chronic adolescent stress: Effects of stress response and the amygdala transcriptome. Genes, Brain, and Behavior. e12493. PMID 29896789 DOI: 10.1111/Gbb.12493  0.796
2017 Yohn NL, Blendy JA. Adolescent Chronic Stress and Adult Anxiety Adolescent Chronic Unpredictable Stress Exposure is a Sensitive Window for Long-Term Changes in Adult Behavior in Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28094283 DOI: 10.1038/npp.2017.11  0.798
2016 Sanchez V, Carpenter MD, Yohn NL, Blendy JA. Long-lasting effects of adolescent oxycodone exposure on reward-related behavior and gene expression in mice. Psychopharmacology. PMID 27624598 DOI: 10.1007/s00213-016-4425-4  0.793
2015 Forcelli PA, Turner JR, Lee BG, Olson TT, Xie T, Xiao Y, Blendy JA, Kellar KJ. Anxiolytic- and Antidepressant-like Effects of the Methadone Metabolite 2-ethyl-5-methyl-3,3-diphenyl-1-pyrroline (EMDP). Neuropharmacology. PMID 26365569 DOI: 10.1016/J.Neuropharm.2015.09.012  0.699
2015 Yohn NL, Bartolomei MS, Blendy JA. Multigenerational and transgenerational inheritance of drug exposure: The effects of alcohol, opiates, cocaine, marijuana, and nicotine. Progress in Biophysics and Molecular Biology. 118: 21-33. PMID 25839742 DOI: 10.1016/J.Pbiomolbio.2015.03.002  0.795
2015 Briand LA, Hilario M, Dow HC, Brodkin ES, Blendy JA, Berton O. Mouse model of OPRM1 (A118G) polymorphism increases sociability and dominance and confers resilience to social defeat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 3582-90. PMID 25716856 DOI: 10.1523/Jneurosci.4685-14.2015  0.684
2015 Briand LA, Lee BG, Lelay J, Kaestner KH, Blendy JA. Serine 133 phosphorylation is not required for hippocampal CREB-mediated transcription and behavior. Learning & Memory (Cold Spring Harbor, N.Y.). 22: 109-15. PMID 25593297 DOI: 10.1101/Lm.037044.114  0.685
2014 Yohn NL, Turner JR, Blendy JA. Activation of α4β2*/α6β2* nicotinic receptors alleviates anxiety during nicotine withdrawal without upregulating nicotinic receptors. The Journal of Pharmacology and Experimental Therapeutics. 349: 348-54. PMID 24627467 DOI: 10.1124/Jpet.113.211706  0.787
2014 Hussmann GP, DeDominicis KE, Turner JR, Yasuda RP, Klehm J, Forcelli PA, Xiao Y, Richardson JR, Sahibzada N, Wolfe BB, Lindstrom J, Blendy JA, Kellar KJ. Chronic sazetidine-A maintains anxiolytic effects and slower weight gain following chronic nicotine without maintaining increased density of nicotinic receptors in rodent brain. Journal of Neurochemistry. 129: 721-31. PMID 24422997 DOI: 10.1111/Jnc.12653  0.687
2014 Turner JR, Ray R, Lee B, Everett L, Xiang J, Jepson C, Kaestner KH, Lerman C, Blendy JA. Evidence from mouse and man for a role of neuregulin 3 in nicotine dependence. Molecular Psychiatry. 19: 801-10. PMID 23999525 DOI: 10.1038/Mp.2013.104  0.551
2013 Gundersen BB, Briand LA, Onksen JL, Lelay J, Kaestner KH, Blendy JA. Increased hippocampal neurogenesis and accelerated response to antidepressants in mice with specific deletion of CREB in the hippocampus: role of cAMP response-element modulator Ï„. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13673-85. PMID 23966689 DOI: 10.1523/Jneurosci.1669-13.2013  0.779
2013 Turner JR, Wilkinson DS, Poole RL, Gould TJ, Carlson GC, Blendy JA. Divergent functional effects of sazetidine-a and varenicline during nicotine withdrawal. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2035-47. PMID 23624742 DOI: 10.1038/Npp.2013.105  0.576
2013 Briand LA, Blendy JA. Not all stress is equal: CREB is not necessary for restraint stress reinstatement of cocaine-conditioned reward. Behavioural Brain Research. 246: 63-8. PMID 23458740 DOI: 10.1016/j.bbr.2013.02.026  0.729
2013 Turner JR, Gold A, Schnoll R, Blendy JA. Translational research in nicotine dependence. Cold Spring Harbor Perspectives in Medicine. 3: a012153. PMID 23335115 DOI: 10.1101/Cshperspect.A012153  0.523
2013 Balu DT, Turner JR, Brookshire BR, Hill-Smith TE, Blendy JA, Lucki I. Brain monoamines and antidepressant-like responses in MRL/MpJ versus C57BL/6J mice. Neuropharmacology. 67: 503-10. PMID 23220293 DOI: 10.1016/J.Neuropharm.2012.11.027  0.571
2013 Turner JR, Ecke LE, Briand LA, Haydon PG, Blendy JA. Cocaine-related behaviors in mice with deficient gliotransmission. Psychopharmacology. 226: 167-76. PMID 23104263 DOI: 10.1007/S00213-012-2897-4  0.799
2013 Wilkinson DS, Turner JR, Blendy JA, Gould TJ. Genetic background influences the effects of withdrawal from chronic nicotine on learning and high-affinity nicotinic acetylcholine receptor binding in the dorsal and ventral hippocampus. Psychopharmacology. 225: 201-8. PMID 22836371 DOI: 10.1007/S00213-012-2808-8  0.538
2012 Hussmann GP, Turner JR, Lomazzo E, Venkatesh R, Cousins V, Xiao Y, Yasuda RP, Wolfe BB, Perry DC, Rezvani AH, Levin ED, Blendy JA, Kellar KJ. Chronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain. The Journal of Pharmacology and Experimental Therapeutics. 343: 441-50. PMID 22899752 DOI: 10.1124/Jpet.112.198085  0.677
2012 Hilario MR, Turner JR, Blendy JA. Reward sensitization: effects of repeated nicotine exposure and withdrawal in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2661-70. PMID 22828747 DOI: 10.1038/Npp.2012.130  0.567
2012 Portugal GS, Wilkinson DS, Turner JR, Blendy JA, Gould TJ. Developmental effects of acute, chronic, and withdrawal from chronic nicotine on fear conditioning. Neurobiology of Learning and Memory. 97: 482-94. PMID 22521799 DOI: 10.1016/J.Nlm.2012.04.003  0.557
2012 Onksen JL, Briand LA, Galante RJ, Pack AI, Blendy JA. Running-induced anxiety is dependent on increases in hippocampal neurogenesis. Genes, Brain, and Behavior. 11: 529-38. PMID 22471438 DOI: 10.1111/J.1601-183X.2012.00788.X  0.778
2012 Briand LA, Lee FS, Blendy JA, Pierce RC. Enhanced extinction of cocaine seeking in brain-derived neurotrophic factor Val66Met knock-in mice. The European Journal of Neuroscience. 35: 932-9. PMID 22394056 DOI: 10.1111/j.1460-9568.2012.08021.x  0.724
2012 Huang P, Chen C, Mague SD, Blendy JA, Liu-Chen LY. A common single nucleotide polymorphism A118G of the μ opioid receptor alters its N-glycosylation and protein stability. The Biochemical Journal. 441: 379-86. PMID 21864297 DOI: 10.1042/Bj20111050  0.772
2011 Onksen JL, Brown EJ, Blendy JA. Selective deletion of a cell cycle checkpoint kinase (ATR) reduces neurogenesis and alters responses in rodent models of behavioral affect. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 960-9. PMID 21248719 DOI: 10.1038/Npp.2010.234  0.799
2011 Ecke LE, Cleck JN, White P, Schug J, Mifflin L, Blendy JA. CREB-mediated alterations in the amygdala transcriptome: coordinated regulation of immune response genes following cocaine. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 1111-26. PMID 21138621 DOI: 10.1017/S1461145710001392  0.785
2011 Turner JR, Castellano LM, Blendy JA. Parallel anxiolytic-like effects and upregulation of neuronal nicotinic acetylcholine receptors following chronic nicotine and varenicline. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 13: 41-6. PMID 21097981 DOI: 10.1093/Ntr/Ntq206  0.56
2010 Briand LA, Vassoler FM, Pierce RC, Valentino RJ, Blendy JA. Ventral tegmental afferents in stress-induced reinstatement: the role of cAMP response element-binding protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16149-59. PMID 21123561 DOI: 10.1523/JNEUROSCI.2827-10.2010  0.738
2010 Mombereau C, Kawahara Y, Gundersen BB, Nishikura K, Blendy JA. Functional relevance of serotonin 2C receptor mRNA editing in antidepressant- and anxiety-like behaviors. Neuropharmacology. 59: 468-73. PMID 20624407 DOI: 10.1016/j.neuropharm.2010.06.009  0.767
2010 Turner JR, Castellano LM, Blendy JA. Nicotinic partial agonists varenicline and sazetidine-A have differential effects on affective behavior. The Journal of Pharmacology and Experimental Therapeutics. 334: 665-72. PMID 20435920 DOI: 10.1124/Jpet.110.166280  0.562
2010 Mague SD, Blendy JA. OPRM1 SNP (A118G): involvement in disease development, treatment response, and animal models. Drug and Alcohol Dependence. 108: 172-82. PMID 20074870 DOI: 10.1016/J.Drugalcdep.2009.12.016  0.777
2010 Mombereau C, Gur TL, Onksen J, Blendy JA. Differential effects of acute and repeated citalopram in mouse models of anxiety and depression. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 13: 321-34. PMID 20003619 DOI: 10.1017/S1461145709990630  0.775
2010 Briand LA, Blendy JA. Molecular and genetic substrates linking stress and addiction. Brain Research. 1314: 219-34. PMID 19900417 DOI: 10.1016/j.brainres.2009.11.002  0.713
2009 Kreibich AS, Briand L, Cleck JN, Ecke L, Rice KC, Blendy JA. Stress-induced potentiation of cocaine reward: a role for CRF R1 and CREB. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2609-17. PMID 19675537 DOI: 10.1038/Npp.2009.91  0.789
2009 Halene TB, Ehrlichman RS, Liang Y, Christian EP, Jonak GJ, Gur TL, Blendy JA, Dow HC, Brodkin ES, Schneider F, Gur RC, Siegel SJ. Assessment of NMDA receptor NR1 subunit hypofunction in mice as a model for schizophrenia. Genes, Brain, and Behavior. 8: 661-75. PMID 19563516 DOI: 10.1111/J.1601-183X.2009.00504.X  0.7
2009 Mague SD, Isiegas C, Huang P, Liu-Chen LY, Lerman C, Blendy JA. Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior. Proceedings of the National Academy of Sciences of the United States of America. 106: 10847-52. PMID 19528658 DOI: 10.1073/Pnas.0901800106  0.783
2009 Isiegas C, Mague SD, Blendy JA. Sex differences in response to nicotine in C57Bl/6:129SvEv mice. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 11: 851-8. PMID 19483179 DOI: 10.1093/Ntr/Ntp076  0.794
2009 Gundersen BB, Blendy JA. Effects of the histone deacetylase inhibitor sodium butyrate in models of depression and anxiety. Neuropharmacology. 57: 67-74. PMID 19393671 DOI: 10.1016/j.neuropharm.2009.04.008  0.64
2008 Kawahara Y, Grimberg A, Teegarden S, Mombereau C, Liu S, Bale TL, Blendy JA, Nishikura K. Dysregulated editing of serotonin 2C receptor mRNAs results in energy dissipation and loss of fat mass. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12834-44. PMID 19036977 DOI: 10.1523/Jneurosci.3896-08.2008  0.701
2008 Cleck JN, Ecke LE, Blendy JA. Endocrine and gene expression changes following forced swim stress exposure during cocaine abstinence in mice. Psychopharmacology. 201: 15-28. PMID 18677617 DOI: 10.1007/S00213-008-1243-3  0.818
2008 Mackler S, Pacchioni A, Degnan R, Homan Y, Conti AC, Kalivas P, Blendy JA. Requirement for the POZ/BTB protein NAC1 in acute but not chronic psychomotor stimulant response. Behavioural Brain Research. 187: 48-55. PMID 17945361 DOI: 10.1016/J.Bbr.2007.08.036  0.349
2007 Gur TL, Conti AC, Holden J, Bechtholt AJ, Hill TE, Lucki I, Malberg JE, Blendy JA. cAMP response element-binding protein deficiency allows for increased neurogenesis and a rapid onset of antidepressant response. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7860-8. PMID 17634380 DOI: 10.1523/Jneurosci.2051-07.2007  0.714
2005 Kreibich AS, Blendy JA. The role of cAMP response element-binding proteins in mediating stress-induced vulnerability to drug abuse. International Review of Neurobiology. 65: 147-78. PMID 16140056 DOI: 10.1016/S0074-7742(04)65006-9  0.795
2005 Walters CL, Cleck JN, Kuo YC, Blendy JA. Mu-opioid receptor and CREB activation are required for nicotine reward. Neuron. 46: 933-43. PMID 15953421 DOI: 10.1016/J.Neuron.2005.05.005  0.619
2005 Blendy JA, Strasser A, Walters CL, Perkins KA, Patterson F, Berkowitz R, Lerman C. Reduced nicotine reward in obesity: cross-comparison in human and mouse. Psychopharmacology. 180: 306-15. PMID 15719224 DOI: 10.1007/S00213-005-2167-9  0.547
2005 Pandey SC, Chartoff EH, Carlezon WA, Zou J, Zhang H, Kreibich AS, Blendy JA, Crews FT. CREB gene transcription factors: role in molecular mechanisms of alcohol and drug addiction. Alcoholism, Clinical and Experimental Research. 29: 176-84. PMID 15714041 DOI: 10.1097/01.Alc.0000153550.31168.1D  0.784
2005 Walters CL, Godfrey M, Li X, Blendy JA. Alterations in morphine-induced reward, locomotor activity, and thermoregulation in CREB-deficient mice. Brain Research. 1032: 193-9. PMID 15680959 DOI: 10.1016/J.Brainres.2004.11.013  0.604
2004 Kreibich AS, Blendy JA. cAMP response element-binding protein is required for stress but not cocaine-induced reinstatement. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6686-92. PMID 15282271 DOI: 10.1523/Jneurosci.1706-04.2004  0.812
2004 Conti AC, Kuo YC, Valentino RJ, Blendy JA. Inducible cAMP early repressor regulates corticosterone suppression after tricyclic antidepressant treatment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1967-75. PMID 14985439 DOI: 10.1523/JNEUROSCI.4804-03.2004  0.326
2003 Walters CL, Kuo YC, Blendy JA. Differential distribution of CREB in the mesolimbic dopamine reward pathway. Journal of Neurochemistry. 87: 1237-44. PMID 14622103 DOI: 10.1046/J.1471-4159.2003.02090.X  0.613
2003 Walters CL, Wang BC, Godfrey M, Sun D, Funk CD, Blendy JA. Augmented responses to morphine and cocaine in mice with a 12-lipoxygenase gene disruption. Psychopharmacology. 170: 124-31. PMID 12845410 DOI: 10.1007/S00213-003-1526-7  0.641
2002 Conti AC, Cryan JF, Dalvi A, Lucki I, Blendy JA. cAMP response element-binding protein is essential for the upregulation of brain-derived neurotrophic factor transcription, but not the behavioral or endocrine responses to antidepressant drugs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3262-8. PMID 11943827 DOI: 10.1523/Jneurosci.22-08-03262.2002  0.626
2001 Walters CL, Blendy JA. Different requirements for cAMP response element binding protein in positive and negative reinforcing properties of drugs of abuse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9438-44. PMID 11717377 DOI: 10.1523/Jneurosci.21-23-09438.2001  0.639
1992 Grimm LJ, Blendy JA, Kellar KJ, Perry DC. Chronic reserpine administration selectively up-regulates beta 1- and alpha 1b-adrenergic receptors in rat brain: an autoradiographic study. Neuroscience. 47: 77-86. PMID 1315939 DOI: 10.1016/0306-4522(92)90122-I  0.504
1991 Blendy JA, Perry DC, Pabreza LA, Kellar KJ. Electroconvulsive shock increases alpha 1b- but not alpha 1a-adrenoceptor binding sites in rat cerebral cortex. Journal of Neurochemistry. 57: 1548-55. PMID 1681031 DOI: 10.1111/j.1471-4159.1991.tb06350.x  0.493
1990 Wahlestedt C, Blendy JA, Kellar KJ, Heilig M, Widerlöv E, Ekman R. Electroconvulsive shocks increase the concentration of neocortical and hippocampal neuropeptide Y (NPY)-like immunoreactivity in the rat. Brain Research. 507: 65-8. PMID 2302581 DOI: 10.1016/0006-8993(90)90523-E  0.508
1990 Blendy JA, Grimm LJ, Perry DC, West-Johnsrud L, Kellar KJ. Electroconvulsive shock differentially increases binding to alpha-1 adrenergic receptor subtypes in discrete regions of rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 2580-6. PMID 1974919  0.485
1988 Blendy JA, Stockmeier CA, Kellar KJ. Electroconvulsive shock and reserpine increase alpha 1-adrenoceptor binding sites but not norepinephrine-stimulated phosphoinositide hydrolysis in rat brain. European Journal of Pharmacology. 156: 267-70. PMID 2853676 DOI: 10.1016/0014-2999(88)90330-5  0.482
1987 Stockmeier CA, McLeskey SW, Blendy JA, Armstrong NR, Kellar KJ. Electroconvulsive shock but not antidepressant drugs increases alpha 1-adrenoceptor binding sites in rat brain. European Journal of Pharmacology. 139: 259-66. PMID 2822432 DOI: 10.1016/0014-2999(87)90582-6  0.522
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