Thomas W. Sturgill - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Pharmacology, Neuroscience Biology

96 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Sturgill TW, Stoddard PB, Cohn SM, Mayo MW. The promoter for intestinal cell kinase is head-to-head with F-Box 9 and contains functional sites for TCF7L2 and FOXA factors. Molecular Cancer. 9: 104. PMID 20459822 DOI: 10.1186/1476-4598-9-104  0.417
2010 Zinzalla V, Sturgill TW, Hall MN. TOR complexes: Composition, structure, and phosphorylation Enzymes. 27: 1-20. DOI: 10.1016/S1874-6047(10)27001-4  0.345
2009 Sturgill TW, Hall MN. Activating mutations in TOR are in similar structures as oncogenic mutations in PI3KCalpha. Acs Chemical Biology. 4: 999-1015. PMID 19902965 DOI: 10.1021/Cb900193E  0.375
2009 Binda M, Péli-Gulli MP, Bonfils G, Panchaud N, Urban J, Sturgill TW, Loewith R, De Virgilio C. The Vam6 GEF controls TORC1 by activating the EGO complex. Molecular Cell. 35: 563-73. PMID 19748353 DOI: 10.1016/J.Molcel.2009.06.033  0.376
2009 Fu Z, Kim J, Vidrich A, Sturgill TW, Cohn SM. Intestinal cell kinase, a MAP kinase-related kinase, regulates proliferation and G1 cell cycle progression of intestinal epithelial cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 297: G632-40. PMID 19696144 DOI: 10.1152/Ajpgi.00066.2009  0.537
2009 Vidrich A, Buzan JM, Brodrick B, Ilo C, Bradley L, Fendig KS, Sturgill T, Cohn SM. Fibroblast growth factor receptor-3 regulates Paneth cell lineage allocation and accrual of epithelial stem cells during murine intestinal development. American Journal of Physiology. Gastrointestinal and Liver Physiology. 297: G168-78. PMID 19407216 DOI: 10.1152/Ajpgi.90589.2008  0.319
2009 Wang L, Lawrence JC, Sturgill TW, Harris TE. Mammalian target of rapamycin complex 1 (mTORC1) activity is associated with phosphorylation of raptor by mTOR. The Journal of Biological Chemistry. 284: 14693-7. PMID 19346248 DOI: 10.1074/Jbc.C109.002907  0.61
2009 Fu Z, Kim J, Vidrich A, Sturgill T, Cohn SM. M1607 Intestinal Cell Kinase Targets the mTOR and CDx2 Pathways to Regulate Proliferation and Differentiation of Intestinal Epithelial Cells Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)61807-2  0.427
2008 Sturgill TW, Cohen A, Diefenbacher M, Trautwein M, Martin DE, Hall MN. TOR1 and TOR2 have distinct locations in live cells. Eukaryotic Cell. 7: 1819-30. PMID 18723607 DOI: 10.1128/Ec.00088-08  0.359
2008 Rowlett RM, Chrestensen CA, Schroeder MJ, Harp MG, Pelo JW, Shabanowitz J, DeRose R, Hunt DF, Sturgill TW, Worthington MT. Inhibition of tristetraprolin deadenylation by poly(A) binding protein. American Journal of Physiology. Gastrointestinal and Liver Physiology. 295: G421-30. PMID 18467502 DOI: 10.1152/Ajpgi.00508.2007  0.392
2008 Sturgill TW. MAP kinase: it's been longer than fifteen minutes. Biochemical and Biophysical Research Communications. 371: 1-4. PMID 18406346 DOI: 10.1016/J.Bbrc.2008.04.002  0.543
2008 Rowlett RM, Chrestensen CA, Nyce M, Harp MG, Pelo JW, Cominelli F, Ernst PB, Pizarro TT, Sturgill TW, Worthington MT. MNK kinases regulate multiple TLR pathways and innate proinflammatory cytokines in macrophages. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G452-9. PMID 18032482 DOI: 10.1152/Ajpgi.00077.2007  0.387
2008 Fu Z, Vidrich A, Sturgill TW, Cohn SM. T1826 Intestinal Cell Kinase Regulates Proliferation of Intestinal Epithelial Cells Gastroenterology. 134: A-571. DOI: 10.1016/S0016-5085(08)62667-0  0.418
2007 Sturgill TW, Hall MN. Holding back TOR advances mitosis. Nature Cell Biology. 9: 1221-2. PMID 17975544 DOI: 10.1038/Ncb1107-1221  0.365
2007 Chrestensen CA, Eschenroeder A, Ross WG, Ueda T, Watanabe-Fukunaga R, Fukunaga R, Sturgill TW. Loss of MNK function sensitizes fibroblasts to serum-withdrawal induced apoptosis. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 12: 1133-40. PMID 17903173 DOI: 10.1111/J.1365-2443.2007.01122.X  0.48
2007 Chrestensen CA, Shuman JK, Eschenroeder A, Worthington M, Gram H, Sturgill TW. MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines. The Journal of Biological Chemistry. 282: 4243-52. PMID 17130135 DOI: 10.1074/Jbc.M607368200  0.497
2007 Martin PM, Aeder SE, Chrestensen CA, Sturgill TW, Hussaini IM. Phorbol 12-myristate 13-acetate and serum synergize to promote rapamycin-insensitive cell proliferation via protein kinase C-eta Oncogene. 26: 407-414. PMID 16832347 DOI: 10.1038/Sj.Onc.1209791  0.557
2006 Devasahayam G, Ritz D, Helliwell SB, Burke DJ, Sturgill TW. Pmr1, a Golgi Ca2+/Mn2+-ATPase, is a regulator of the target of rapamycin (TOR) signaling pathway in yeast. Proceedings of the National Academy of Sciences of the United States of America. 103: 17840-5. PMID 17095607 DOI: 10.1073/Pnas.0604303103  0.409
2006 Fu Z, Larson KA, Chitta RK, Parker SA, Turk BE, Lawrence MW, Kaldis P, Galaktionov K, Cohn SM, Shabanowitz J, Hunt DF, Sturgill TW. Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase. Molecular and Cellular Biology. 26: 8639-54. PMID 16954377 DOI: 10.1128/Mcb.00816-06  0.594
2006 Ranganathan A, Pearson GW, Chrestensen CA, Sturgill TW, Cobb MH. The MAP kinase ERK5 binds to and phosphorylates p90 RSK. Archives of Biochemistry and Biophysics. 449: 8-16. PMID 16626623 DOI: 10.1016/J.Abb.2006.02.023  0.607
2005 Fu Z, Schroeder MJ, Shabanowitz J, Kaldis P, Togawa K, Rustgi AK, Hunt DF, Sturgill TW. Activation of a nuclear Cdc2-related kinase within a mitogen-activated protein kinase-like TDY motif by autophosphorylation and cyclin-dependent protein kinase-activating kinase. Molecular and Cellular Biology. 25: 6047-64. PMID 15988018 DOI: 10.1128/Mcb.25.14.6047-6064.2005  0.633
2004 Srinivasan S, Bolick DT, Hatley ME, Natarajan R, Reilly KB, Yeh M, Chrestensen C, Sturgill TW, Hedrick CC. Glucose regulates interleukin-8 production in aortic endothelial cells through activation of the p38 mitogen-activated protein kinase pathway in diabetes. The Journal of Biological Chemistry. 279: 31930-6. PMID 15145956 DOI: 10.1074/Jbc.M400753200  0.39
2004 Jiang L, Niu S, Clines KL, Burke DJ, Sturgill TW. Analyses of the effects of Rck2p mutants on Pbs2pDD-induced toxicity in Saccharomyces cerevisiae identify a MAP kinase docking motif, and unexpected functional inactivation due to acidic substitution of T379. Molecular Genetics and Genomics : Mgg. 271: 208-19. PMID 14735355 DOI: 10.1007/s00438-003-0972-6  0.47
2004 Chrestensen CA, Schroeder MJ, Shabanowitz J, Hunt DF, Pelo JW, Worthington MT, Sturgill TW. MAPKAP kinase 2 phosphorylates tristetraprolin on in vivo sites including Ser178, a site required for 14-3-3 binding. The Journal of Biological Chemistry. 279: 10176-84. PMID 14688255 DOI: 10.1074/Jbc.M310486200  0.487
2002 Halvorsen EM, Dennis J, Keeney P, Sturgill TW, Tuttle JB, Bennett JB. Methylpyridinium (MPP(+))- and nerve growth factor-induced changes in pro- and anti-apoptotic signaling pathways in SH-SY5Y neuroblastoma cells. Brain Research. 952: 98-110. PMID 12363409 DOI: 10.1016/S0006-8993(02)03216-X  0.728
2002 Chrestensen CA, Sturgill TW. Characterization of the p90 ribosomal S6 kinase 2 carboxyl-terminal domain as a protein kinase. The Journal of Biological Chemistry. 277: 27733-41. PMID 12016217 DOI: 10.1074/Jbc.M202663200  0.611
2001 Santiago J, Sturgill TW. Identification of the S6 kinase activity stimulated in quiescent brine shrimp embryos upon entry to preemergence development as p70 ribosomal protein S6 kinase: Isolation of Artemia franciscana p70S6k cDNA Biochemistry and Cell Biology. 79: 141-152. PMID 11310561 DOI: 10.1139/bcb-79-2-141  0.509
2000 McPherson RA, Taylor MM, Hershey ED, Sturgill TW. A different function for a critical tryptophan in c-Raf and Hck. Oncogene. 19: 3616-22. PMID 10951567 DOI: 10.1038/Sj.Onc.1203678  0.427
2000 Smith JA, Poteet-Smith CE, Lannigan DA, Freed TA, Zoltoski AJ, Sturgill TW. Creation of a stress-activated p90 ribosomal S6 kinase. The carboxyl-terminal tail of the MAPK-activated protein kinases dictates the signal transduction pathway in which they function Journal of Biological Chemistry. 275: 31588-31593. PMID 10922375 DOI: 10.1074/Jbc.M005892200  0.623
2000 Cassarino DS, Halvorsen EM, Swerdlow RH, Abramova NN, Parker WD, Sturgill TW, Bennett JP. Interaction among mitochondria, mitogen-activated protein kinases, and nuclear factor-kappaB in cellular models of Parkinson's disease. Journal of Neurochemistry. 74: 1384-92. PMID 10737593 DOI: 10.1046/J.1471-4159.2000.0741384.X  0.723
1999 Poteet-Smith CE, Smith JA, Lannigan DA, Freed TA, Sturgill TW. Generation of constitutively active p90 ribosomal S6 kinase in vivo. Implications for the mitogen-activated protein kinase-activated protein kinase family Journal of Biological Chemistry. 274: 22135-22138. PMID 10428774 DOI: 10.1074/Jbc.274.32.22135  0.625
1999 Smith JA, Poteet-Smith CE, Malarkey K, Sturgill TW. Identification of an extracellular signal-regulated kinase (ERK) docking site in ribosomal S6 kinase, a sequence critical for activation by ERK in vivo Journal of Biological Chemistry. 274: 2893-2898. PMID 9915826 DOI: 10.1074/Jbc.274.5.2893  0.621
1998 Joel PB, Smith J, Sturgill TW, Fisher TL, Blenis J, Lannigan DA. pp90rsk1 regulates estrogen receptor-mediated transcription through phosphorylation of Ser-167. Molecular and Cellular Biology. 18: 1978-84. PMID 9528769 DOI: 10.1128/Mcb.18.4.1978  0.479
1998 Malarkey K, Coker KJ, Sturgill TW. Ribosomal S6 kinase is activated as an early event in preemergence development of encysted embryos of Artemia salina European Journal of Biochemistry. 251: 269-274. PMID 9492293 DOI: 10.1046/J.1432-1327.1998.2510269.X  0.576
1997 Dent P, Wang Y, Gu YZ, Wood SL, Reardon DB, Mangues R, Pellicer A, Schonbrunn A, Sturgill TW. S49 cells endogenously express subtype 2 somatostatin receptors which couple to increase protein tyrosine phosphatase activity in membranes and down-regulate Raf-1 activity in situ. Cellular Signalling. 9: 539-49. PMID 9419818 DOI: 10.1016/S0898-6568(97)00048-X  0.44
1997 Reardon DB, Dent P, Wood SL, Kong T, Sturgill TW. Activation in vitro of somatostatin receptor subtypes 2, 3, or 4 stimulates protein tyrosine phosphatase activity in membranes from transfected Ras-transformed nih 3T3 cells: Coexpression with catalytically inactive SHP-2 blocks responsiveness Molecular Endocrinology. 11: 1062-1069. PMID 9212054 DOI: 10.1210/Mend.11.8.9960  0.432
1997 Stancato LF, Sakatsume M, David M, Dent P, Dong F, Petricoin EF, Krolewski JJ, Silvennoinen O, Saharinen P, Pierce J, Marshall CJ, Sturgill T, Finbloom DS, Larner AC. Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway. Molecular and Cellular Biology. 17: 3833-3840. PMID 9199317 DOI: 10.1128/Mcb.17.7.3833  0.588
1997 Burack WR, Sturgill TW. The activating dual phosphorylation of MAPK by MEK is nonprocessive Biochemistry. 36: 5929-5933. PMID 9166761 DOI: 10.1021/bi970535d  0.557
1997 Rani CS, Wang F, Fuior E, Berger A, Wu J, Sturgill TW, Beitner-Johnson D, LeRoith D, Varticovski L, Spiegel S. Divergence in signal transduction pathways of platelet-derived growth factor (PDGF) and epidermal growth factor (EGF) receptors. Involvement of sphingosine 1-phosphate in PDGF but not EGF signaling. The Journal of Biological Chemistry. 272: 10777-83. PMID 9099730 DOI: 10.1074/Jbc.272.16.10777  0.619
1997 Sprenkle AB, Davies SP, Carling D, Hardie DG, Sturgill TW. Identification of Raf-1 Ser621 kinase activity from NIH 3T3 cells as AMP-activated protein kinase. Febs Letters. 403: 254-8. PMID 9091312 DOI: 10.1016/S0014-5793(97)00062-8  0.619
1996 Kasid U, Suy S, Dent P, Ray S, Whiteside TL, Sturgill TW. Activation of Raf by ionizing radiation Nature. 382: 813-816. PMID 8752275 DOI: 10.1038/382813A0  0.544
1996 Reardon DB, Wood SL, Brautigan DL, Bell GI, Dent P, Sturgill TW. Activation of a protein tyrosine phosphatase and inactivation of Raf-1 by somatostatin. The Biochemical Journal. 314: 401-4. PMID 8670047 DOI: 10.1042/Bj3140401  0.534
1996 Trofimova M, Sprenkle AB, Green M, Sturgill TW, Goebl MG, Harrington MA. Developmental and tissue-specific expression of mouse pelle-like protein kinase Journal of Biological Chemistry. 271: 17609-17612. PMID 8663605 DOI: 10.1074/Jbc.271.30.17609  0.525
1996 Jelinek T, Dent P, Sturgill TW, Weber MJ. Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation Molecular and Cellular Biology. 16: 1027-1034. PMID 8622647 DOI: 10.1128/Mcb.16.3.1027  0.51
1996 Dent P, Reardon DB, Wood SL, Lindorfer MA, Graber SG, Garrison JC, Brautigan DL, Sturgill TW. Inactivation of raf-1 by a protein-tyrosine phosphatase stimulated by GTP and reconstituted by Galphai/o subunits. The Journal of Biological Chemistry. 271: 3119-23. PMID 8621710 DOI: 10.1074/Jbc.271.6.3119  0.387
1995 Dent P, Romero G, Castle D, Sturgill TW. Preparation and use of semiintact mammalian cells for analysis of signal transduction Methods in Enzymology. 255: 265-273. PMID 8524110 DOI: 10.1016/S0076-6879(95)55029-1  0.303
1995 Wu J, Spiegel S, Sturgill TW. Sphingosine 1-phosphate rapidly activates the mitogen-activated protein kinase pathway by a G protein-dependent mechanism. The Journal of Biological Chemistry. 270: 11484-8. PMID 7744787 DOI: 10.1074/Jbc.270.19.11484  0.608
1995 Dent P, Reardon DB, Morrison DK, Sturgill TW. Regulation of Raf-1 and Raf-1 mutants by Ras-dependent and Ras- independent mechanisms in vitro Molecular and Cellular Biology. 15: 4125-4135. PMID 7623807 DOI: 10.1128/Mcb.15.8.4125  0.504
1995 Dent P, Jelinek T, Morrison DK, Weber MJ, Sturgill TW. Reversal of Raf-1 activation by purified and membrane associated protein phosphatases Science. 268: 1902-1906. PMID 7604263 DOI: 10.1126/Science.7604263  0.512
1995 Aziz N, Miglarese MR, Hendrickson RC, Shabanowitz J, Sturgill TW, Hunt DF, Bender TP. Modulation of c-Myb-induced transcription activation by a phosphorylation site near the negative regulatory domain. Proceedings of the National Academy of Sciences of the United States of America. 92: 6429-33. PMID 7604007 DOI: 10.1073/Pnas.92.14.6429  0.496
1995 Chow YH, Pumiglia K, Jun TH, Dent P, Sturgill TW, Jove R. Functional mapping of the N-terminal regulatory domain in the human Raf-1 protein kinase Journal of Biological Chemistry. 270: 14100-14106. PMID 7539798 DOI: 10.1074/Jbc.270.23.14100  0.582
1994 Rossomando AJ, Dent P, Sturgill TW, Marshak DR. Mitogen-activated protein kinase kinase 1 (MKK1) is negatively regulated by threonine phosphorylation Molecular and Cellular Biology. 14: 1594-1602. PMID 8114697  0.553
1994 T.diaz-Meco M, Dominguez I, Sanz L, Dent P, Lozano J, Municio MM, Berra E, Hay RT, Sturgill TW, Moscat J. ζPKC induces phosphorylation and inactivation of lχB-α in vitro Embo Journal. 13: 2842-2848. PMID 8026469  0.558
1994 Dent P, Chow YH, Wu J, Morrison DK, Jove R, Sturgill TW. Expression, purification and characterization of recombinant mitogen-activated protein kinase kinases. The Biochemical Journal. 303: 105-12. PMID 7945229 DOI: 10.1042/Bj3030105  0.61
1994 Dent P, Sturgill TW. Activation of (His)6-Raf-1 in vitro by partially purified plasma membranes from v-Ras-transformed and serum-stimulated fibroblasts Proceedings of the National Academy of Sciences of the United States of America. 91: 9544-9548. PMID 7937802 DOI: 10.1073/Pnas.91.20.9544  0.503
1994 Wu J, Lau LF, Sturgill TW. Rapid deactivation of MAP kinase in PC12 cells occurs independently of induction of phosphatase MKP-1. Febs Letters. 353: 9-12. PMID 7926031 DOI: 10.1016/0014-5793(94)01000-5  0.534
1994 Taagepera S, Dent P, Her JH, Sturgill TW, Gorbsky GJ. The MPM-2 antibody inhibits mitogen-activated protein kinase activity by binding to an epitope containing phosphothreonine-183 Molecular Biology of the Cell. 5: 1243-1251. PMID 7532473 DOI: 10.1091/Mbc.5.11.1243  0.513
1993 Haystead CMM, Gregory P, Sturgill TW, Haystead TAJ. γ-Phosphate-linked ATP-Sepharose for the affinity purification of protein kinases. Rapid purification to homogeneity of skeletal muscle mitogen-activated protein kinase kinase European Journal of Biochemistry. 214: 459-467. PMID 8513796 DOI: 10.1111/J.1432-1033.1993.Tb17942.X  0.563
1993 Haystead CMM, Wu J, Gregory P, Sturgill TW, Haystead TAJ. Functional expression of a MAP kinase kinase in COS cells and recognition by an anti-STE7/byrl antibody Febs Letters. 317: 12-16. PMID 8428620 DOI: 10.1016/0014-5793(93)81481-E  0.597
1993 Wu J, Michel H, Dent P, Haystead T, Hunt DF, Sturgill TW. Activation of MAP kinase by a dual specificity Tyr/Thr kinase Advances in Second Messenger and Phosphoprotein Research. 28: 219-225. PMID 8398407  0.502
1993 Wu J, Harrison JK, Dent P, Lynch KR, Weber MJ, Sturgill TW. Identification and Characterization of a New Mammalian Mitogen-Activated Protein Kinase Kinase, MKK2 Molecular and Cellular Biology. 13: 4539-4548. PMID 8393135 DOI: 10.1128/Mcb.13.8.4539  0.612
1993 Wu J, Harrison JK, Vincent LA, Haystead C, Haystead TAJ, Michel H, Hunt DF, Lynch KR, Sturgill TW. Molecular structure of a protein-tyrosine/threonine kinase activating p42 mitogen-activated protein (MAP) kinase: MAP kinase kinase Proceedings of the National Academy of Sciences of the United States of America. 90: 173-177. PMID 8380494 DOI: 10.1073/Pnas.90.1.173  0.587
1993 Aziz N, Wu J, Dubendorff JW, Lipsick JS, Sturgill TW, Bender TP. c-Myb and v-Myb are differentially phosphorylated by p42mapk in vitro. Oncogene. 8: 2259-65. PMID 8336948  0.378
1993 Dent P, Wu J, Romero G, Vincent LA, Castle D, Sturgill TW. Activation of the mitogen-activated protein kinase pathway in Triton X- 100 disrupted NIH-3T3 cells by p21 ras and in vitro by plasma membranes from NIH 3T3 cells Molecular Biology of the Cell. 4: 483-493. PMID 8334304 DOI: 10.1091/Mbc.4.5.483  0.545
1993 Wu J, Dent P, Jelinek T, Wolfman A, Weber MJ, Sturgill TW. Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-monophosphate Science. 262: 1065-1072. PMID 7694366 DOI: 10.1126/Science.7694366  0.634
1993 Her JH, Lakhani S, Zu K, Vila J, Dent P, Sturgill TW, Weber MJ. Dual phosphorylation and autophosphorylation in mitogen-activated protein (MAP) kinase activation Biochemical Journal. 296: 25-31. PMID 7504457 DOI: 10.1042/BJ2960025  0.543
1992 Haystead TAJ, Dent P, Wu J, Haystead CMM, Sturgill TW. Ordered phosphorylation of p42mapk by MAP kinase kinase Febs Letters. 306: 17-22. PMID 1628739 DOI: 10.1016/0014-5793(92)80828-5  0.57
1992 Wu J, Michel H, Rossomando A, Haystead T, Shabanwitz J, Hunt DF, Sturgill TW. Renaturation and partial peptide sequencing of mitogen-activated protein kinase (MAP kinase) activator from rabbit skeletal muscle Biochemical Journal. 285: 701-705. PMID 1379797 DOI: 10.1042/Bj2850701  0.581
1992 Rossomando AJ, Wu J, Michel H, Shabanowitz J, Hunt DF, Weber MJ, Sturgill TW. Identification of Tyr-185 as the site of tyrosine autophosphorylation of recombinant mitogen-activated protein kinase p42mapk Proceedings of the National Academy of Sciences of the United States of America. 89: 5779-5783. PMID 1378617 DOI: 10.1073/Pnas.89.13.5779  0.579
1992 Wu J, Rossomando AJ, Horng-Her J, Weber TMJ, Sturgill TW. Apparent sufficiency of a dual-specificity tyrosine/threonine kinase for activation of MAP kinase poses new questions for the dual-phosphorylation mechanism Biochemical Society Transactions. 20: 675-677. PMID 1330785 DOI: 10.1042/Bst0200675  0.578
1992 Dent P, Haser W, Haystead TAJ, Vincent LA, Roberts TM, Sturgill TW. Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro Science. 257: 1404-1407. PMID 1326789 DOI: 10.1126/Science.1326789  0.63
1992 Rossomando A, Wu J, Weber MJ, Sturgill TW. The phorbol ester-dependent activator of the mitogen-activated protein kinase p42mapk is a kinase with specificity for the threonine and tyrosine regulatory sites Proceedings of the National Academy of Sciences of the United States of America. 89: 5221-5225. PMID 1319055 DOI: 10.1073/Pnas.89.12.5221  0.619
1992 L'Allemain G, Her JH, Wu J, Sturgill TW, Weber MJ. Growth factor-induced activation of a kinase activity which causes regulatory phosphorylation of p42/microtubule-associated protein kinase Molecular and Cellular Biology. 12: 2222-2229. PMID 1314951 DOI: 10.1128/Mcb.12.5.2222  0.641
1991 L'Allemain G, Sturgill TW, Weber MJ. Defective regulation of mitogen-activaed protein kinase activity in a 3T3 cell variant mitogenically nonresponsive to tetradecanoyl phorbol acetate Molecular and Cellular Biology. 11: 1002-1008. PMID 1990261 DOI: 10.1128/Mcb.11.2.1002  0.629
1991 Payne DM, Rossomando AJ, Martino P, Erickson AK, Her JH, Shabanowitz J, Hunt DF, Weber MJ, Sturgill TW. Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase). The Embo Journal. 10: 885-92. PMID 1849075  0.526
1991 Wu J, Rossomando AJ, Her JH, Del Vecchio R, Weber MJ, Sturgill TW. Autophosphorylation in vitro of recombinant 42-kilodalton mitogen-activated protein kinase on tyrosine. Proceedings of the National Academy of Sciences of the United States of America. 88: 9508-12. PMID 1835084 DOI: 10.1073/Pnas.88.21.9508  0.62
1991 Sturgill TW, Ray LB, Anderson NG, Erickson AK. Purification of mitogen-activated protein kinase from epidermal growth factor-treated 3T3-L1 fibroblasts. Methods in Enzymology. 200: 342-51. PMID 1720187 DOI: 10.1016/0076-6879(91)00151-L  0.472
1991 Andersen NG, Kilgour E, Sturgill TW. Activation of mitogen-activated protein kinase in BC3H1 myocytes by fluoroaluminate Journal of Biological Chemistry. 266: 10131-10135. PMID 1709925  0.559
1991 Rossomando AJ, Sanghera JS, Marsden LA, Weber MJ, Pelech SL, Sturgill TW. Biochemical characterization of a family of serine/threonine protein kinases regulated by tyrosine and serine/threonine phosphorylations. The Journal of Biological Chemistry. 266: 20270-5. PMID 1657919  0.54
1991 Anderson NG, Li P, Marsden LA, Williams N, Roberts TM, Sturgill TW. Raf-1 is a potential substrate for mitogen-activated protein kinase in vivo Biochemical Journal. 277: 573-576. PMID 1650188 DOI: 10.1042/Bj2770573  0.571
1991 Her Jh, Wu J, Rall TB, Sturgill TW, Weber MJ. Sequence of pp42/MAP kinase, a serine/threonine kinase regulated by tyrosine phosphorylation Nucleic Acids Research. 19: 3743. PMID 1649458 DOI: 10.1093/Nar/19.13.3743  0.556
1991 Sturgill TW, Jie Wu. Recent progress in characterization of protein kinase cascades for phosphorylation of ribosomal protein S6 Bba - Molecular Cell Research. 1092: 350-357. PMID 1646641 DOI: 10.1016/S0167-4889(97)90012-4  0.601
1991 Payne DM, Rossomando AJ, Martino P, Erickson AK, Her JH, Shabanowitz J, Hunt DF, Weber MJ, Sturgill TW. Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase). The Embo Journal. 10: 885-892. DOI: 10.1002/J.1460-2075.1991.Tb08021.X  0.59
1990 Erickson AK, Ray LB, Sturgill TW. Microtubule-associated protein 1A is the fibroblast HMW MAP undergoing mitogen-stimulated serine phosphorylation. Biochemical and Biophysical Research Communications. 166: 827-32. PMID 2405857 DOI: 10.1016/0006-291X(90)90884-P  0.446
1990 Anderson NG, Maller JL, Tonks NK, Sturgill TW. Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase Nature. 343: 651-653. PMID 2154696 DOI: 10.1038/343651A0  0.613
1990 Erickson AK, Payne DM, Martino PA, Rossomando AJ, Shabanowitz J, Weber MJ, Hunt DF, Sturgill TW. Identification by mass spectrometry of threonine 97 in bovine myelin basic protein as a specific phosphorylation site for mitogen-activated protein kinase. The Journal of Biological Chemistry. 265: 19728-35. PMID 1700979  0.442
1990 Ely CM, Oddie KM, Litz JS, Rossomando AJ, Kanner SB, Sturgill TW, Parsons SJ. A 42-kD tyrosine kinase substrate linked to chromaffin cell secretion exhibits an associated MAP kinase activity and is highly related to a 42-kD mitogen-stimulated protein in fibroblasts Journal of Cell Biology. 110: 731-742. PMID 1689732 DOI: 10.1083/Jcb.110.3.731  0.5
1989 Rossomando AJ, Payne DM, Weber MJ, Sturgill TW. Evidence that pp42, a major tyrosine kinase target protein, is a mitogen-activated serine/threonine protein kinase Proceedings of the National Academy of Sciences of the United States of America. 86: 6940-6943. PMID 2550926 DOI: 10.1073/Pnas.86.18.6940  0.609
1989 Silliman CC, Sturgill TW. Phosphorylation of microtubule-associated protein 2 by map kinase primarily involves the projection domain Biochemical and Biophysical Research Communications. 160: 993-998. PMID 2543402 DOI: 10.1016/S0006-291X(89)80099-3  0.544
1988 Ray LB, Sturgill TW. Insulin-stimulated microtubule-associated protein kinase is phosphorylated on tyrosine and threonine in vivo Proceedings of the National Academy of Sciences of the United States of America. 85: 3753-3757. PMID 3287375  0.472
1988 Ray LB, Sturgill TW. Insulin-stimulated microtubule associated protein kinase is detectable by analytical gel chromatography as a 35-kDa protein in myocytes, adipocytes, and hepatocytes Archives of Biochemistry and Biophysics. 262: 307-313. PMID 3281589 DOI: 10.1016/0003-9861(88)90193-2  0.482
1988 Sturgill TW, Ray LB, Erikson E, Maller JL. Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II. Nature. 334: 715-8. PMID 2842685 DOI: 10.1038/334715A0  0.537
1988 Ray LB, Sturgill TW. Characterization of insulin-stimulated microtubule-associated protein kinase. Rapid isolation and stabilization of a novel serine/threonine kinase from 3T3-L1 cells Journal of Biological Chemistry. 263: 12721-12727. PMID 2842341  0.437
1987 Ray LB, Sturgill TW. Rapid stimulation by insulin of a serine/threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubule-associated protein 2 in vitro (ribosomal protein S6 kinase/phosphatase inhibitors) Proceedings of the National Academy of Sciences of the United States of America. 84: 1502-1506. PMID 2951732  0.5
1986 Sturgill TW, Ray LB. Muscle proteins related to microtubule associated protein-2 are substrates for an insulin-stimulatable kinase Biochemical and Biophysical Research Communications. 134: 565-571. PMID 3511906 DOI: 10.1016/S0006-291X(86)80457-0  0.368
1983 Speaker MG, Orlow SJ, Sturgill TW, Rosen OM. Characterization of a calmodulin-binding protein that is deficient in trifluoperazine-resistant variants of the macrophage-like cell line J774 Proceedings of the National Academy of Sciences of the United States of America. 80: 329-333. PMID 6572895 DOI: 10.1073/Pnas.80.2.329  0.394
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