Carol Colton - Publications

Affiliations: 
Georgetown University Medical Center, Washington, DC, United States 
Area:
Neuroscience Biology

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Shi C, Gottschalk WK, Colton CA, Mukherjee S, Lutz MW. Alzheimer's Disease Protein Relevance Analysis Using Human and Mouse Model Proteomics Data. Frontiers in Systems Biology. 3. PMID 37650081 DOI: 10.3389/fsysb.2023.1085577  0.316
2022 Whitson HE, Colton C, El Khoury J, Gate D, Goate A, Heneka MT, Kaddurah-Daouk R, Klein RS, Shinohara ML, Sisodia S, Spudich SS, Stevens B, Tanzi R, Ting JP, Garden G. Infection and inflammation: New perspectives on Alzheimer's disease. Brain, Behavior, & Immunity - Health. 22: 100462. PMID 36118272 DOI: 10.1016/j.bbih.2022.100462  0.323
2021 York A, Everhart A, Vitek MP, Gottschalk KW, Colton CA. Metabolism-Based Gene Differences in Neurons Expressing Hyperphosphorylated AT8- Positive (AT8+) Tau in Alzheimer's Disease. Asn Neuro. 13: 17590914211019443. PMID 34121475 DOI: 10.1177/17590914211019443  0.303
2021 Adams KJ, Wilson JG, Millington DS, Moseley MA, Colton CA, Thompson JW, Gottschalk WK. Capillary Electrophoresis-High Resolution Mass Spectrometry for Measuring In Vivo Arginine Isotope Incorporation in Alzheimer's Disease Mouse Models. Journal of the American Society For Mass Spectrometry. PMID 34028275 DOI: 10.1021/jasms.1c00055  0.305
2021 Bryan J, Mandan A, Kamat G, Gottschalk WK, Badea A, Adams KJ, Thompson JW, Colton CA, Mukherjee S, Lutz MW. Likelihood ratio statistics for gene set enrichment in Alzheimer's disease pathways. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33480182 DOI: 10.1002/alz.12223  0.307
2019 Badea A, Delpratt NA, Anderson RJ, Dibb R, Qi Y, Wei H, Liu C, Wetsel WC, Avants BB, Colton C. Multivariate MR biomarkers better predict cognitive dysfunction in mouse models of Alzheimer's disease. Magnetic Resonance Imaging. PMID 30940494 DOI: 10.1016/J.Mri.2019.03.022  0.365
2015 Kan MJ, Lee JE, Wilson JG, Everhart AL, Brown CM, Hoofnagle AN, Jansen M, Vitek MP, Gunn MD, Colton CA. Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5969-82. PMID 25878270 DOI: 10.1523/JNEUROSCI.4668-14.2015  0.426
2014 Hoos MD, Vitek MP, Ridnour LA, Wilson J, Jansen M, Everhart A, Wink DA, Colton CA. The impact of human and mouse differences in NOS2 gene expression on the brain's redox and immune environment. Molecular Neurodegeneration. 9: 50. PMID 25403885 DOI: 10.1186/1750-1326-9-50  0.307
2014 Colton CA, Wilson JG, Everhart A, Wilcock DM, Puoliväli J, Heikkinen T, Oksman J, Jääskeläinen O, Lehtimäki K, Laitinen T, Vartiainen N, Vitek MP. mNos2 deletion and human NOS2 replacement in Alzheimer disease models. Journal of Neuropathology and Experimental Neurology. 73: 752-69. PMID 25003233 DOI: 10.1097/NEN.0000000000000094  0.64
2013 Hoos MD, Richardson BM, Foster MW, Everhart A, Thompson JW, Moseley MA, Colton CA. Longitudinal study of differential protein expression in an Alzheimer's mouse model lacking inducible nitric oxide synthase. Journal of Proteome Research. 12: 4462-77. PMID 24006891 DOI: 10.1021/Pr4005103  0.417
2012 Ridnour LA, Dhanapal S, Hoos M, Wilson J, Lee J, Cheng RY, Brueggemann EE, Hines HB, Wilcock DM, Vitek MP, Wink DA, Colton CA. Nitric oxide-mediated regulation of β-amyloid clearance via alterations of MMP-9/TIMP-1. Journal of Neurochemistry. 123: 736-49. PMID 23016931 DOI: 10.1111/Jnc.12028  0.562
2012 Xu F, Vitek MP, Colton CA, Previti ML, Davis J, Van Nostrand WE. Human apolipoprotein E2 promotes parenchymal amyloid deposition and neuronal loss in vasculotropic mutant amyloid-β protein Tg-SwDI mice. Journal of Alzheimer's Disease : Jad. 31: 359-69. PMID 22635103 DOI: 10.3233/JAD-2012-120421  0.37
2012 Sudduth TL, Wilson JG, Everhart A, Colton CA, Wilcock DM. Lithium treatment of APPSwDI/NOS2-/- mice leads to reduced hyperphosphorylated tau, increased amyloid deposition and altered inflammatory phenotype. Plos One. 7: e31993. PMID 22347510 DOI: 10.1371/journal.pone.0031993  0.619
2012 Vitek MP, Christensen DJ, Wilcock D, Davis J, Van Nostrand WE, Li FQ, Colton CA. APOE-mimetic peptides reduce behavioral deficits, plaques and tangles in Alzheimer's disease transgenics. Neuro-Degenerative Diseases. 10: 122-6. PMID 22326991 DOI: 10.1159/000334914  0.632
2011 Wilcock DM, Zhao Q, Morgan D, Gordon MN, Everhart A, Wilson JG, Lee JE, Colton CA. Diverse inflammatory responses in transgenic mouse models of Alzheimer's disease and the effect of immunotherapy on these responses. Asn Neuro. 3: 249-58. PMID 21995345 DOI: 10.1042/An20110018  0.72
2011 Shineman DW, Basi GS, Bizon JL, Colton CA, Greenberg BD, Hollister BA, Lincecum J, Leblanc GG, Lee LB, Luo F, Morgan D, Morse I, Refolo LM, Riddell DR, Scearce-Levie K, et al. Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies. Alzheimer's Research & Therapy. 3: 28. PMID 21943025 DOI: 10.1186/Alzrt90  0.574
2011 Wilcock DM, Morgan D, Gordon MN, Taylor TL, Ridnour LA, Wink DA, Colton CA. Activation of matrix metalloproteinases following anti-Aβ immunotherapy; implications for microhemorrhage occurrence. Journal of Neuroinflammation. 8: 115. PMID 21906275 DOI: 10.1186/1742-2094-8-115  0.683
2011 Wilcock DM, Colton CA. Anti-amyloid-β immunotherapy in Alzheimer's disease: Relevance of transgenic mouse studies to clinical trials Advances in Alzheimer's Disease. 1: 247-261. DOI: 10.3233/978-1-60750-733-8-247  0.354
2010 Van Nostrand WE, Xu F, Rozemuller AJ, Colton CA. Enhanced capillary amyloid angiopathy-associated pathology in Tg-SwDI mice with deleted nitric oxide synthase 2. Stroke; a Journal of Cerebral Circulation. 41: S135-8. PMID 20876489 DOI: 10.1161/STROKEAHA.110.595272  0.327
2010 Colton C, Wilcock DM. Assessing activation states in microglia. Cns & Neurological Disorders Drug Targets. 9: 174-91. PMID 20205642  0.568
2010 Wu J, Yoo S, Wilcock D, Lytle JM, Leung PY, Colton CA, Wrathall JR. Interaction of NG2(+) glial progenitors and microglia/macrophages from the injured spinal cord. Glia. 58: 410-22. PMID 19780197 DOI: 10.1002/Glia.20932  0.482
2010 Wilcock DM, Gharkholonarehe N, Van Nostrand WE, Davis J, Vitek MP, Colton CA. Amyloid reduction by amyloid-β vaccination also reduces mouse tau pathology and protects from neuron loss in two mouse models of Alzheimer's disease (The Journal of Neuroscience (2009) (7957-7965)) Journal of Neuroscience. 30: 1197-1198.  0.328
2009 Wilcock DM, Gharkholonarehe N, Van Nostrand WE, Davis J, Vitek MP, Colton CA. Amyloid reduction by amyloid-beta vaccination also reduces mouse tau pathology and protects from neuron loss in two mouse models of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7957-65. PMID 19553436 DOI: 10.1523/JNEUROSCI.1339-09.2009  0.62
2009 Wilcock DM, Vitek MP, Colton CA. Vascular amyloid alters astrocytic water and potassium channels in mouse models and humans with Alzheimer's disease. Neuroscience. 159: 1055-69. PMID 19356689 DOI: 10.1016/j.neuroscience.2009.01.023  0.604
2009 Wilcock DM, Colton CA. Immunotherapy, vascular pathology, and microhemorrhages in transgenic mice. Cns & Neurological Disorders Drug Targets. 8: 50-64. PMID 19275636 DOI: 10.2174/187152709787601858  0.625
2009 Vitek MP, Brown CM, Colton CA. APOE genotype-specific differences in the innate immune response. Neurobiology of Aging. 30: 1350-60. PMID 18155324 DOI: 10.1016/j.neurobiolaging.2007.11.014  0.322
2009 Vitek MP, Christensen DJ, Wilcock D, Oddo J, Gharkholonarehe N, Ohkubo N, Toku K, Van Nostrand WE, Li F, Colton CA. O2-04-05: Novel mechanism where ApoE mimetics activate PP2A activity and reduce Alzheimer's pathology in three different transgenic models Alzheimer's & Dementia. 5: P111-P111. DOI: 10.1016/j.jalz.2009.05.347  0.561
2009 Colton CA, Vitek MP, Wilcock D. O1-03-04: Testing the amyloid cascade hypothesis in a novel mouse model of Alzheimer's disease that shows complete disease progression Alzheimer's & Dementia. 5: P82-P83. DOI: 10.1016/j.jalz.2009.05.208  0.573
2008 Colton CA, Wilcock DM, Wink DA, Davis J, Van Nostrand WE, Vitek MP. The effects of NOS2 gene deletion on mice expressing mutated human AbetaPP. Journal of Alzheimer's Disease : Jad. 15: 571-87. PMID 19096157 DOI: 10.3233/Jad-2008-15405  0.663
2008 Wilcock DM, Colton CA. Anti-amyloid-beta immunotherapy in Alzheimer's disease: relevance of transgenic mouse studies to clinical trials. Journal of Alzheimer's Disease : Jad. 15: 555-69. PMID 19096156  0.607
2008 Xu F, Vitek MP, Colton CA, Previti ML, Gharkholonarehe N, Davis J, Van Nostrand WE. Human apolipoprotein E redistributes fibrillar amyloid deposition in Tg-SwDI mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 5312-20. PMID 18480287 DOI: 10.1523/JNEUROSCI.1042-08.2008  0.356
2008 Wilcock DM, Lewis MR, Van Nostrand WE, Davis J, Previti ML, Gharkholonarehe N, Vitek MP, Colton CA. Progression of amyloid pathology to Alzheimer's disease pathology in an amyloid precursor protein transgenic mouse model by removal of nitric oxide synthase 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1537-45. PMID 18272675 DOI: 10.1523/JNEUROSCI.5066-07.2008  0.643
2008 Brown CM, Choi E, Xu Q, Vitek MP, Colton CA. The APOE4 genotype alters the response of microglia and macrophages to 17beta-estradiol. Neurobiology of Aging. 29: 1783-94. PMID 17553597 DOI: 10.1016/j.neurobiolaging.2007.04.018  0.32
2008 Colton CA, Wilcock DM, Davis J, Van Nostrand W, Vitek MP. P1-050: Progression to a full spectrum of Alzheimer's-like pathology in animal models of amyloid deposition by reduction in NOS2 Alzheimer's & Dementia. 4: T220-T220. DOI: 10.1016/j.jalz.2008.05.635  0.578
2008 Wilcock DM, Vitek MP, Colton CA. P4-291: Cerebral amyloid angiopathy results in neurovascular unit disruption in transgenic mouse models of Alzheimer's disease Alzheimer's & Dementia. 4: T756-T757. DOI: 10.1016/j.jalz.2008.05.2360  0.596
2007 Brown CM, Xu Q, Okhubo N, Vitek MP, Colton CA. Androgen-mediated immune function is altered by the apolipoprotein E gene. Endocrinology. 148: 3383-90. PMID 17395708 DOI: 10.1210/en.2006-1200  0.338
2006 Colton CA, Mott RT, Sharpe H, Xu Q, Van Nostrand WE, Vitek MP. Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD. Journal of Neuroinflammation. 3: 27. PMID 17005052 DOI: 10.1186/1742-2094-3-27  0.377
2006 Colton CA, Vitek MP, Wink DA, Xu Q, Cantillana V, Previti ML, Van Nostrand WE, Weinberg JB, Weinberg B, Dawson H. NO synthase 2 (NOS2) deletion promotes multiple pathologies in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 103: 12867-72. PMID 16908860 DOI: 10.1073/pnas.0601075103  0.364
2006 Colton C, Wink D, Weinberg JB, Nostrand WV, Dawson H, Vitek M. O29. Nitric oxide is neuroprotective in a mouse model of Aβ-mediated chronic neurodegeneration Nitric Oxide. 14: 9. DOI: 10.1016/J.Niox.2006.04.033  0.374
2004 Colton CA, Needham LK, Brown C, Cook D, Rasheed K, Burke JR, Strittmatter WJ, Schmechel DE, Vitek MP. APOE genotype-specific differences in human and mouse macrophage nitric oxide production. Journal of Neuroimmunology. 147: 62-7. PMID 14741429 DOI: 10.1016/J.Jneuroim.2003.10.015  0.402
2003 Czapiga M, Colton CA. Microglial function in human APOE3 and APOE4 transgenic mice: altered arginine transport. Journal of Neuroimmunology. 134: 44-51. PMID 12507771 DOI: 10.1016/S0165-5728(02)00394-6  0.706
2002 Colton CA, Brown CM, Cook D, Needham LK, Xu Q, Czapiga M, Saunders AM, Schmechel DE, Rasheed K, Vitek MP. APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress. Neurobiology of Aging. 23: 777-85. PMID 12392781 DOI: 10.1016/S0197-4580(02)00016-7  0.735
2002 Colton CA, Brown CM, Czapiga M, Vitek MP. Apolipoprotein-E allele-specific regulation of nitric oxide production. Annals of the New York Academy of Sciences. 962: 212-25. PMID 12076977 DOI: 10.1111/J.1749-6632.2002.Tb04070.X  0.734
2002 Brown CM, Wright E, Colton CA, Sullivan PM, Laskowitz DT, Vitek MP. Apolipoprotein E isoform mediated regulation of nitric oxide release. Free Radical Biology & Medicine. 32: 1071-5. PMID 12031891 DOI: 10.1016/S0891-5849(02)00803-1  0.371
2001 Wink DA, Miranda KM, Espey MG, Pluta RM, Hewett SJ, Colton C, Vitek M, Feelisch M, Grisham MB. Mechanisms of the antioxidant effects of nitric oxide. Antioxidants & Redox Signaling. 3: 203-13. PMID 11396476 DOI: 10.1089/152308601300185179  0.302
2001 Colton CA, Czapiga M, Snell-Callanan J, Chernyshev ON, Vitek MP. Apolipoprotein E acts to increase nitric oxide production in macrophages by stimulating arginine transport. Biochimica Et Biophysica Acta. 1535: 134-44. PMID 11342002 DOI: 10.1016/S0925-4439(00)00092-2  0.7
2000 Colton CA, Chernyshev ON, Gilbert DL, Vitek MP. Microglial contribution to oxidative stress in Alzheimer's disease Annals of the New York Academy of Sciences. 899: 292-307. PMID 10863548  0.343
2000 Colton CA, Czapiga M, Chernyshev ON, Vitek MP. The APoE4 allele is associated with enhanced nitric oxide production and enhanced arginine transport Neurobiology of Aging. 21: 254-255. DOI: 10.1016/S0197-4580(00)83095-X  0.664
1999 Czapiga M, Colton CA. Function of microglia in organotypic slice cultures. Journal of Neuroscience Research. 56: 644-51. PMID 10374819 DOI: 10.1002/(Sici)1097-4547(19990615)56:6<644::Aid-Jnr10>3.0.Co;2-9  0.665
1997 Vitek MP, Snell J, Dawson H, Colton CA. Modulation of nitric oxide production in human macrophages by apolipoprotein-E and amyloid-beta peptide Biochemical and Biophysical Research Communications. 240: 391-394. PMID 9388488 DOI: 10.1006/bbrc.1997.7408  0.398
1996 Colton C, Wilt S, Gilbert D, Chernyshev O, Snell J, Dubois-Dalcq M. Species differences in the generation of reactive oxygen species by microglia Molecular and Chemical Neuropathology. 28: 15-20. PMID 8871937 DOI: 10.1007/Bf02815200  0.386
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