Itzhak Fischer, PhD - Publications

Affiliations: 
Neurobiology and Anatomy Drexel University College of Medicine, Philadelphia, PA, United States 
Area:
Neuroscience, Stem Cell Biology, Spinal cord injury
Website:
http://drexel.edu/medicine/faculty/profiles/itzhak-fischer/

74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Partyka PP, Jin Y, Bouyer J, DaSilva A, Godsey GA, Nagele RG, Fischer I, Galie PA. Harnessing neurovascular interaction to guide axon growth. Scientific Reports. 9: 2190. PMID 30778117 DOI: 10.1038/s41598-019-38558-y  1
2018 Zholudeva LV, Iyer NR, Qiang L, Spruance VM, Randelman ML, White NW, Bezdudnaya T, Fischer I, Sakiyama-Elbert SE, Lane MA. Transplantation of Neural Progenitors and V2a Interneurons after Spinal Cord Injury. Journal of Neurotrauma. PMID 29873284 DOI: 10.1089/neu.2017.5439  1
2018 Cunningham TJ, Greenstein JI, Yao L, Fischer I, Conners T. Heptamer peptide disassembles native amyloid in human plasma via Heat Shock Protein 70. Rejuvenation Research. PMID 29651925 DOI: 10.1089/rej.2017.2049  1
2018 Jin Y, Shumsky JS, Fischer I. Axonal regeneration of different tracts following transplants of human glial restricted progenitors into the injured spinal cord in rats. Brain Research. PMID 29408659 DOI: 10.1016/j.brainres.2018.01.030  1
2017 Merianda TT, Jin Y, Kalinski AL, Sahoo PK, Fischer I, Twiss JL. Neural Progenitor Cells Promote Axonal Growth and Alter Axonal mRNA Localization in Adult Neurons. Eneuro. 4. PMID 28197547 DOI: 10.1523/ENEURO.0171-16.2017  1
2016 Lane MA, Lepore AC, Fischer I. Improving the therapeutic efficacy of neural progenitor cell transplantation following spinal cord injury. Expert Review of Neurotherapeutics. PMID 27927055 DOI: 10.1080/14737175.2017.1270206  1
2016 Krupka AJ, Fischer I, Lemay MA. Transplants of neurotrophin-producing autologous fibroblasts promote recovery of treadmill stepping in the acute, sub-chronic, and chronic spinal cat. Journal of Neurotrauma. PMID 27829315 DOI: 10.1089/neu.2016.4559  1
2016 Yuan XB, Haas C, Fischer I. Guiding the migration of grafted cells to promote axon regeneration. Neural Regeneration Research. 11: 1224-5. PMID 27651760 DOI: 10.4103/1673-5374.189169  1
2016 Hayakawa K, Haas C, Fischer I. Examining the properties and therapeutic potential of glial restricted precursors in spinal cord injury. Neural Regeneration Research. 11: 529-33. PMID 27212899 DOI: 10.4103/1673-5374.180725  1
2016 Fischer I, Haas C, Raghupathi R, Jin Y. Spinal cord concussion: studying the potential risks of repetitive injury. Neural Regeneration Research. 11: 58-60. PMID 26981079 DOI: 10.4103/1673-5374.169634  1
2016 Yuan XB, Jin Y, Haas C, Yao L, Hayakawa K, Wang Y, Wang C, Fischer I. Guiding migration of transplanted glial progenitor cells in the injured spinal cord. Scientific Reports. 6: 22576. PMID 26971438 DOI: 10.1038/srep22576  1
2016 Jin Y, Bouyer J, Shumsky JS, Haas C, Fischer I. Transplantation of neural progenitor cells in chronic spinal cord injury. Neuroscience. PMID 26852702 DOI: 10.1016/j.neuroscience.2016.01.066  1
2015 Hayakawa K, Haas C, Jin Y, Bouyer J, Otsuka T, Fischer I. Glial restricted precursors maintain their permissive properties after long-term expansion but not following exposure to pro-inflammatory factors. Brain Research. PMID 26498878 DOI: 10.1016/j.brainres.2015.10.022  1
2015 Jin Y, Bouyer J, Haas C, Fischer I. Evaluation of the anatomical and functional consequences of repetitive mild cervical contusion using a model of spinal concussion. Experimental Neurology. 271: 175-188. PMID 26070306 DOI: 10.1016/j.expneurol.2015.06.001  1
2015 Kwon BK, Streijger F, Hill CE, Anderson AJ, Bacon M, Beattie MS, Blesch A, Bradbury EJ, Brown A, Bresnahan JC, Case CC, Colburn RW, David S, Fawcett JW, Ferguson AR, ... Fischer I, et al. Large animal and primate models of spinal cord injury for the testing of novel therapies. Experimental Neurology. 269: 154-68. PMID 25902036 DOI: 10.1016/j.expneurol.2015.04.008  1
2015 Ollivier-Lanvin K, Fischer I, Tom V, Houlé JD, Lemay MA. Either brain-derived neurotrophic factor or neurotrophin-3 only neurotrophin-producing grafts promote locomotor recovery in untrained spinalized cats. Neurorehabilitation and Neural Repair. 29: 90-100. PMID 24803493 DOI: 10.1177/1545968314532834  1
2014 Haas C, Fischer I. Transplanting neural progenitors to build a neuronal relay across the injured spinal cord. Neural Regeneration Research. 9: 1173-6. PMID 25206777 DOI: 10.4103/1673-5374.135321  1
2014 Jin Y, Bouyer J, Haas C, Fischer I. Behavioral and anatomical consequences of repetitive mild thoracic spinal cord contusion injury in the rat. Experimental Neurology. 257: 57-69. PMID 24786492 DOI: 10.1016/j.expneurol.2014.04.016  1
2014 Medalha CC, Jin Y, Yamagami T, Haas C, Fischer I. Transplanting neural progenitors into a complete transection model of spinal cord injury. Journal of Neuroscience Research. 92: 607-18. PMID 24452691 DOI: 10.1002/jnr.23340  1
2013 Bonner JF, Haas CJ, Fischer I. Preparation of neural stem cells and progenitors: neuronal production and grafting applications. Methods in Molecular Biology (Clifton, N.J.). 1078: 65-88. PMID 23975822 DOI: 10.1007/978-1-62703-640-5_7  1
2013 Haas C, Fischer I. Human astrocytes derived from glial restricted progenitors support regeneration of the injured spinal cord. Journal of Neurotrauma. 30: 1035-52. PMID 23635322 DOI: 10.1089/neu.2013.2915  1
2013 Grous LC, Vernengo J, Jin Y, Himes BT, Shumsky JS, Fischer I, Lowman A. Implications of poly(N-isopropylacrylamide)-g-poly(ethylene glycol) with codissolved brain-derived neurotrophic factor injectable scaffold on motor function recovery rate following cervical dorsolateral funiculotomy in the rat. Journal of Neurosurgery. Spine. 18: 641-52. PMID 23581453 DOI: 10.3171/2013.3.SPINE12874  1
2013 Saglam A, Perets A, Canver AC, Li HL, Kollins K, Cohen G, Fischer I, Lazarovici P, Lelkes PI. Angioneural crosstalk in scaffolds with oriented microchannels for regenerative spinal cord injury repair. Journal of Molecular Neuroscience : Mn. 49: 334-46. PMID 22878912 DOI: 10.1007/s12031-012-9863-9  1
2012 Blesch A, Fischer I, Tuszynski MH. Gene therapy, neurotrophic factors and spinal cord regeneration. Handbook of Clinical Neurology. 109: 563-74. PMID 23098737 DOI: 10.1016/B978-0-444-52137-8.00035-8  1
2012 Jin Y, Sura K, Fischer I. Differential effects of distinct central nervous system regions on cell migration and axonal extension of neural precursor transplants. Journal of Neuroscience Research. 90: 2065-73. PMID 22740505 DOI: 10.1002/jnr.23099  1
2012 Haas C, Neuhuber B, Yamagami T, Rao M, Fischer I. Phenotypic analysis of astrocytes derived from glial restricted precursors and their impact on axon regeneration. Experimental Neurology. 233: 717-32. PMID 22101004 DOI: 10.1016/j.expneurol.2011.11.002  1
2011 Mitsui T, Neuhuber B, Fischer I. Acute administration of AMPA/Kainate blocker combined with delayed transplantation of neural precursors improves lower urinary tract function in spinal injured rats. Brain Research. 1418: 23-31. PMID 21937028 DOI: 10.1016/j.brainres.2011.08.023  1
2011 Conova L, Vernengo J, Jin Y, Himes BT, Neuhuber B, Fischer I, Lowman A, Vernengo J, Jin Y, Himes BT, Neuhuber B, Fischer I, Lowman A. A pilot study of poly(N-isopropylacrylamide)-g-polyethylene glycol and poly(N-isopropylacrylamide)-g-methylcellulose branched copolymers as injectable scaffolds for local delivery of neurotrophins and cellular transplants into the injured spinal cord. Journal of Neurosurgery. Spine. 15: 594-604. PMID 21888482 DOI: 10.3171/2011.7.SPINE11194  1
2011 Francis NL, Shanbhag MS, Fischer I, Wheatley MA. Influence of alginate cross-linking method on neurite response to microencapsulated neurotrophin-producing fibroblasts. Journal of Microencapsulation. 28: 353-62. PMID 21736520 DOI: 10.3109/02652048.2011.569765  1
2011 Jin Y, Ketschek A, Jiang Z, Smith G, Fischer I. Chondroitinase activity can be transduced by a lentiviral vector in vitro and in vivo Journal of Neuroscience Methods. 199: 208-213. PMID 21600922 DOI: 10.1016/j.jneumeth.2011.05.007  1
2011 Lepore AC, O'Donnell J, Bonner JF, Paul C, Miller ME, Rauck B, Kushner RA, Rothstein JD, Fischer I, Maragakis NJ. Spatial and temporal changes in promoter activity of the astrocyte glutamate transporter GLT1 following traumatic spinal cord injury. Journal of Neuroscience Research. 89: 1001-17. PMID 21488085 DOI: 10.1002/jnr.22624  1
2011 Bonner JF, Connors TM, Silverman WF, Kowalski DP, Lemay MA, Fischer I. Grafted neural progenitors integrate and restore synaptic connectivity across the injured spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4675-86. PMID 21430166 DOI: 10.1523/JNEUROSCI.4130-10.2011  1
2011 Jin Y, Neuhuber B, Singh A, Bouyer J, Lepore A, Bonner J, Himes T, Campanelli JT, Fischer I. Transplantation of human glial restricted progenitors and derived astrocytes into a contusion model of spinal cord injury. Journal of Neurotrauma. 28: 579-94. PMID 21222572 DOI: 10.1089/neu.2010.1626  1
2010 Zhukareva V, Obrocka M, Houle JD, Fischer I, Neuhuber B. Secretion profile of human bone marrow stromal cells: donor variability and response to inflammatory stimuli. Cytokine. 50: 317-21. PMID 20185331 DOI: 10.1016/j.cyto.2010.01.004  1
2010 See J, Bonner J, Neuhuber B, Fischer I. Neurite outgrowth of neural progenitors in presence of inhibitory proteoglycans. Journal of Neurotrauma. 27: 951-7. PMID 20102265 DOI: 10.1089/neu.2009.1158  1
2010 Bonner JF, Blesch A, Neuhuber B, Fischer I. Promoting directional axon growth from neural progenitors grafted into the injured spinal cord. Journal of Neuroscience Research. 88: 1182-92. PMID 19908250 DOI: 10.1002/jnr.22288  1
2009 Samdani AF, Paul C, Betz RR, Fischer I, Neuhuber B. Transplantation of human marrow stromal cells and mono-nuclear bone marrow cells into the injured spinal cord: a comparative study. Spine. 34: 2605-12. PMID 19881401 DOI: 10.1097/BRS.0b013e3181bdca87  1
2009 Paul C, Samdani AF, Betz RR, Fischer I, Neuhuber B. Grafting of human bone marrow stromal cells into spinal cord injury: a comparison of delivery methods. Spine. 34: 328-34. PMID 19182705 DOI: 10.1097/BRS.0b013e31819403ce  1
2009 Comolli N, Neuhuber B, Fischer I, Lowman A. In vitro analysis of PNIPAAm-PEG, a novel, injectable scaffold for spinal cord repair. Acta Biomaterialia. 5: 1046-55. PMID 19054721 DOI: 10.1016/j.actbio.2008.10.008  1
2008 Neuhuber B, Barshinger AL, Paul C, Shumsky JS, Mitsui T, Fischer I. Stem cell delivery by lumbar puncture as a therapeutic alternative to direct injection into injured spinal cord. Journal of Neurosurgery. Spine. 9: 390-9. PMID 18939929 DOI: 10.3171/SPI.2008.9.10.390  1
2008 Neuhuber B, Swanger SA, Howard L, Mackay A, Fischer I. Effects of plating density and culture time on bone marrow stromal cell characteristics. Experimental Hematology. 36: 1176-85. PMID 18495329 DOI: 10.1016/j.exphem.2008.03.019  1
2007 Boyce VS, Tumolo M, Fischer I, Murray M, Lemay MA. Neurotrophic factors promote and enhance locomotor recovery in untrained spinalized cats. Journal of Neurophysiology. 98: 1988-96. PMID 17652412 DOI: 10.1152/jn.00391.2007  1
2006 Lepore AC, Neuhuber B, Connors TM, Han SS, Liu Y, Daniels MP, Rao MS, Fischer I. Long-term fate of neural precursor cells following transplantation into developing and adult CNS. Neuroscience. 142: 287-304. PMID 17120358  1
2006 Yoshihara H, Shumsky JS, Neuhuber B, Otsuka T, Fischer I, Murray M. Combining motor training with transplantation of rat bone marrow stromal cells does not improve repair or recovery in rats with thoracic contusion injuries. Brain Research. 1119: 65-75. PMID 17027672 DOI: 10.1016/j.brainres.2006.08.080  1
2006 Lepore AC, Walczak P, Rao MS, Fischer I, Bulte JW. MR imaging of lineage-restricted neural precursors following transplantation into the adult spinal cord. Experimental Neurology. 201: 49-59. PMID 16764862 DOI: 10.1016/j.expneurol.2006.03.032  1
2006 Park KI, Himes BT, Stieg PE, Tessler A, Fischer I, Snyder EY. Neural stem cells may be uniquely suited for combined gene therapy and cell replacement: Evidence from engraftment of Neurotrophin-3-expressing stem cells in hypoxic-ischemic brain injury. Experimental Neurology. 199: 179-90. PMID 16714016 DOI: 10.1016/j.expneurol.2006.03.016  1
2006 Himes BT, Neuhuber B, Coleman C, Kushner R, Swanger SA, Kopen GC, Wagner J, Shumsky JS, Fischer I. Recovery of function following grafting of human bone marrow-derived stromal cells into the injured spinal cord. Neurorehabilitation and Neural Repair. 20: 278-96. PMID 16679505 DOI: 10.1177/1545968306286976  1
2006 Lepore AC, Neuhuber B, Connors TM, Han SS, Liu Y, Daniels MP, Rao MS, Fischer I. Long-term fate of neural precursor cells following transplantation into developing and adult CNS. Neuroscience. 139: 513-30. PMID 16458439 DOI: 10.1016/j.neuroscience.2005.12.043  1
2006 Bakshi A, Barshinger AL, Swanger SA, Madhavani V, Shumsky JS, Neuhuber B, Fischer I. Lumbar puncture delivery of bone marrow stromal cells in spinal cord contusion: a novel method for minimally invasive cell transplantation. Journal of Neurotrauma. 23: 55-65. PMID 16430372 DOI: 10.1089/neu.2006.23.55  1
2005 Swanger SA, Neuhuber B, Himes BT, Bakshi A, Fischer I. Analysis of allogeneic and syngeneic bone marrow stromal cell graft survival in the spinal cord. Cell Transplantation. 14: 775-86. PMID 16454352 DOI: 10.3727/000000005783982594  1
2005 Hayashi Y, Shumsky JS, Connors T, Otsuka T, Fischer I, Tessler A, Murray M. Immunosuppression with either cyclosporine a or FK506 supports survival of transplanted fibroblasts and promotes growth of host axons into the transplant after spinal cord injury. Journal of Neurotrauma. 22: 1267-81. PMID 16305315 DOI: 10.1089/neu.2005.22.1267  1
2005 Mitsui T, Shumsky JS, Lepore AC, Murray M, Fischer I. Transplantation of neuronal and glial restricted precursors into contused spinal cord improves bladder and motor functions, decreases thermal hypersensitivity, and modifies intraspinal circuitry. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9624-36. PMID 16237167 DOI: 10.1523/JNEUROSCI.2175-05.2005  1
2005 Mitsui T, Fischer I, Shumsky JS, Murray M. Transplants of fibroblasts expressing BDNF and NT-3 promote recovery of bladder and hindlimb function following spinal contusion injury in rats. Experimental Neurology. 194: 410-31. PMID 16022868 DOI: 10.1016/j.expneurol.2005.02.022  1
2005 Lepore AC, Bakshi A, Swanger SA, Rao MS, Fischer I. Neural precursor cells can be delivered into the injured cervical spinal cord by intrathecal injection at the lumbar cord. Brain Research. 1045: 206-16. PMID 15910779 DOI: 10.1016/j.brainres.2005.03.050  1
2005 Lepore AC, Fischer I. Lineage-restricted neural precursors survive, migrate, and differentiate following transplantation into the injured adult spinal cord. Experimental Neurology. 194: 230-42. PMID 15899260 DOI: 10.1016/j.expneurol.2005.02.020  1
2005 Neuhuber B, Timothy Himes B, Shumsky JS, Gallo G, Fischer I. Axon growth and recovery of function supported by human bone marrow stromal cells in the injured spinal cord exhibit donor variations. Brain Research. 1035: 73-85. PMID 15713279 DOI: 10.1016/j.brainres.2004.11.055  1
2005 Li P, Tessler A, Han SS, Fischer I, Rao MS, Selzer ME. Fate of immortalized human neuronal progenitor cells transplanted in rat spinal cord. Archives of Neurology. 62: 223-9. PMID 15710850 DOI: 10.1001/archneur.62.2.223  1
2005 Tobias CA, Han SS, Shumsky JS, Kim D, Tumolo M, Dhoot NO, Wheatley MA, Fischer I, Tessler A, Murray M. Alginate encapsulated BDNF-producing fibroblast grafts permit recovery of function after spinal cord injury in the absence of immune suppression. Journal of Neurotrauma. 22: 138-56. PMID 15665609 DOI: 10.1089/neu.2005.22.138  1
2005 Tint I, Fischer I, Black MM. Acute inactivation of MAP1b in growing sympathetic neurons destabilizes axonal microtubules Cell Motility and the Cytoskeleton. 60: 48-65. PMID 15573412 DOI: 10.1002/cm.20045  1
2004 Lepore AC, Han SS, Tyler-Polsz CJ, Cai J, Rao MS, Fischer I. Differential fate of multipotent and lineage-restricted neural precursors following transplantation into the adult CNS. Neuron Glia Biology. 1: 113-26. PMID 16520830 DOI: 10.1017/s1740925x04000213  1
2004 Liu Y, Han SS, Wu Y, Tuohy TM, Xue H, Cai J, Back SA, Sherman LS, Fischer I, Rao MS. CD44 expression identifies astrocyte-restricted precursor cells. Developmental Biology. 276: 31-46. PMID 15531362 DOI: 10.1016/j.ydbio.2004.08.018  1
2004 Bakshi A, Hunter C, Swanger S, Lepore A, Fischer I. Minimally invasive delivery of stem cells for spinal cord injury: advantages of the lumbar puncture technique. Journal of Neurosurgery. Spine. 1: 330-7. PMID 15478372 DOI: 10.3171/spi.2004.1.3.0330  1
2004 Bakshi A, Fisher O, Dagci T, Himes BT, Fischer I, Lowman A. Mechanically engineered hydrogel scaffolds for axonal growth and angiogenesis after transplantation in spinal cord injury. Journal of Neurosurgery. Spine. 1: 322-9. PMID 15478371 DOI: 10.3171/spi.2004.1.3.0322  1
2004 Dhoot NO, Tobias CA, Fischer I, Wheatley MA. Peptide-modified alginate surfaces as a growth permissive substrate for neurite outgrowth. Journal of Biomedical Materials Research. Part A. 71: 191-200. PMID 15376189 DOI: 10.1002/jbm.a.30103  1
2004 Neuhuber B, Gallo G, Howard L, Kostura L, Mackay A, Fischer I. Reevaluation of in vitro differentiation protocols for bone marrow stromal cells: disruption of actin cytoskeleton induces rapid morphological changes and mimics neuronal phenotype. Journal of Neuroscience Research. 77: 192-204. PMID 15211586 DOI: 10.1002/jnr.20147  1
2004 Murray M, Fischer I, Smeraski C, Tessler A, Giszter S. Towards a definition of recovery of function. Journal of Neurotrauma. 21: 405-13. PMID 15115590 DOI: 10.1089/089771504323004557  1
2004 Han SS, Liu Y, Tyler-Polsz C, Rao MS, Fischer I. Transplantation of glial-restricted precursor cells into the adult spinal cord: survival, glial-specific differentiation, and preferential migration in white matter. Glia. 45: 1-16. PMID 14648541 DOI: 10.1002/glia.10282  1
2003 Emery DL, Royo NC, Fischer I, Saatman KE, McIntosh TK. Plasticity following injury to the adult central nervous system: is recapitulation of a developmental state worth promoting? Journal of Neurotrauma. 20: 1271-92. PMID 14748977 DOI: 10.1089/089771503322686085  1
2002 Liu Y, Himes BT, Murray M, Tessler A, Fischer I. Grafts of BDNF-producing fibroblasts rescue axotomized rubrospinal neurons and prevent their atrophy. Experimental Neurology. 178: 150-64. PMID 12504875 DOI: 10.1006/exnr.2002.7977  1
2002 Jin Y, Fischer I, Tessler A, Houle JD. Transplants of fibroblasts genetically modified to express BDNF promote axonal regeneration from supraspinal neurons following chronic spinal cord injury. Experimental Neurology. 177: 265-75. PMID 12429228 DOI: 10.1006/exnr.2002.7980  1
2002 Han SS, Kang DY, Mujtaba T, Rao MS, Fischer I. Grafted lineage-restricted precursors differentiate exclusively into neurons in the adult spinal cord. Experimental Neurology. 177: 360-75. PMID 12429183  1
2002 Wu YY, Mujtaba T, Han SS, Fischer I, Rao MS. Isolation of a glial-restricted tripotential cell line from embryonic spinal cord cultures. Glia. 38: 65-79. PMID 11921204 DOI: 10.1002/glia.10049  1
2002 Mujtaba T, Han SS, Fischer I, Sandgren EP, Rao MS. Stable expression of the alkaline phosphatase marker gene by neural cells in culture and after transplantation into the CNS using cells derived from a transgenic rat. Experimental Neurology. 174: 48-57. PMID 11869033 DOI: 10.1006/exnr.2001.7847  1
2000 Han SS, Fischer I. Neural stem cells and gene therapy: prospects for repairing the injured spinal cord. Jama. 283: 2300-1. PMID 10807395  1
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