Itzhak Fischer, PhD - Publications

Neurobiology and Anatomy Drexel University College of Medicine, Philadelphia, PA, United States 
Neuroscience, Stem Cell Biology, Spinal cord injury

137 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Tran KA, DeOre BJ, Ikejiani D, Means K, Paone LS, De Marchi L, Suprewicz Ł, Koziol K, Bouyer J, Byfield FJ, Jin Y, Georges P, Fischer I, Janmey PA, Galie PA. Matching mechanical heterogeneity of the native spinal cord augments axon infiltration in 3D-printed scaffolds. Biomaterials. 295: 122061. PMID 36842339 DOI: 10.1016/j.biomaterials.2023.122061  0.416
2022 Tran KA, Jin Y, Bouyer J, DeOre BJ, Suprewicz Ł, Figel A, Walens H, Fischer I, Galie PA. Magnetic alignment of injectable hydrogel scaffolds for spinal cord injury repair. Biomaterials Science. PMID 35352727 DOI: 10.1039/d1bm01590g  0.349
2022 Hayakawa K, Jin Y, Bouyer J, Connors TM, Otsuka T, Fischer I. Transplanting Neural Progenitor Cells into a Chronic Dorsal Column Lesion Model. Biomedicines. 10. PMID 35203559 DOI: 10.3390/biomedicines10020350  0.517
2021 Zholudeva LV, Jin Y, Qiang L, Lane MA, Fischer I. Preparation of Neural Stem Cells and Progenitors: Neuronal Production and Grafting Applications. Methods in Molecular Biology (Clifton, N.J.). 2311: 73-108. PMID 34033079 DOI: 10.1007/978-1-0716-1437-2_7  0.467
2020 Fischer I, Dulin JN, Lane MA. Transplanting neural progenitor cells to restore connectivity after spinal cord injury. Nature Reviews. Neuroscience. PMID 32518349 DOI: 10.1038/S41583-020-0314-2  0.598
2020 Fischer I, Baas PW. Resurrecting the Mysteries of Big Tau. Trends in Neurosciences. PMID 32434664 DOI: 10.1016/J.Tins.2020.04.007  0.358
2020 Tran KA, Partyka PP, Jin Y, Bouyer J, Fischer I, Galie PA. Vascularization of self-assembled peptide scaffolds for spinal cord injury repair. Acta Biomaterialia. PMID 31904559 DOI: 10.1016/J.Actbio.2019.12.033  0.546
2019 Partyka PP, Jin Y, Bouyer J, DaSilva A, Godsey GA, Nagele RG, Fischer I, Galie PA. Harnessing neurovascular interaction to guide axon growth. Scientific Reports. 9: 2190. PMID 30778117 DOI: 10.1038/S41598-019-38558-Y  0.557
2018 Zholudeva LV, Iyer NR, Qiang L, Spruance VM, Randelman ML, White NW, Bezdudnaya T, Fischer I, Sakiyama-Elbert SE, Lane MA. Transplantation of Neural Progenitors and V2a Interneurons after Spinal Cord Injury. Journal of Neurotrauma. PMID 29873284 DOI: 10.1089/Neu.2017.5439  0.633
2018 Jin Y, Shumsky JS, Fischer I. Axonal regeneration of different tracts following transplants of human glial restricted progenitors into the injured spinal cord in rats. Brain Research. PMID 29408659 DOI: 10.1016/J.Brainres.2018.01.030  0.483
2017 Merianda TT, Jin Y, Kalinski AL, Sahoo PK, Fischer I, Twiss JL. Neural Progenitor Cells Promote Axonal Growth and Alter Axonal mRNA Localization in Adult Neurons. Eneuro. 4. PMID 28197547 DOI: 10.1523/ENEURO.0171-16.2017  0.68
2016 Lane MA, Lepore AC, Fischer I. Improving the therapeutic efficacy of neural progenitor cell transplantation following spinal cord injury. Expert Review of Neurotherapeutics. PMID 27927055 DOI: 10.1080/14737175.2017.1270206  0.765
2016 Krupka AJ, Fischer I, Lemay MA. Transplants of neurotrophin-producing autologous fibroblasts promote recovery of treadmill stepping in the acute, sub-chronic, and chronic spinal cat. Journal of Neurotrauma. PMID 27829315 DOI: 10.1089/neu.2016.4559  0.707
2016 Yuan XB, Haas C, Fischer I. Guiding the migration of grafted cells to promote axon regeneration. Neural Regeneration Research. 11: 1224-5. PMID 27651760 DOI: 10.4103/1673-5374.189169  0.737
2016 Hayakawa K, Haas C, Fischer I. Examining the properties and therapeutic potential of glial restricted precursors in spinal cord injury. Neural Regeneration Research. 11: 529-33. PMID 27212899 DOI: 10.4103/1673-5374.180725  0.75
2016 Fischer I, Haas C, Raghupathi R, Jin Y. Spinal cord concussion: studying the potential risks of repetitive injury. Neural Regeneration Research. 11: 58-60. PMID 26981079 DOI: 10.4103/1673-5374.169634  0.769
2016 Yuan XB, Jin Y, Haas C, Yao L, Hayakawa K, Wang Y, Wang C, Fischer I. Guiding migration of transplanted glial progenitor cells in the injured spinal cord. Scientific Reports. 6: 22576. PMID 26971438 DOI: 10.1038/Srep22576  0.768
2016 Jin Y, Bouyer J, Shumsky JS, Haas C, Fischer I. Transplantation of neural progenitor cells in chronic spinal cord injury. Neuroscience. PMID 26852702 DOI: 10.1016/J.Neuroscience.2016.01.066  0.726
2015 Hayakawa K, Haas C, Jin Y, Bouyer J, Otsuka T, Fischer I. Glial restricted precursors maintain their permissive properties after long-term expansion but not following exposure to pro-inflammatory factors. Brain Research. PMID 26498878 DOI: 10.1016/J.Brainres.2015.10.022  0.741
2015 Jin Y, Bouyer J, Haas C, Fischer I. Evaluation of the anatomical and functional consequences of repetitive mild cervical contusion using a model of spinal concussion. Experimental Neurology. 271: 175-188. PMID 26070306 DOI: 10.1016/J.Expneurol.2015.06.001  0.711
2015 Kwon BK, Streijger F, Hill CE, Anderson AJ, Bacon M, Beattie MS, Blesch A, Bradbury EJ, Brown A, Bresnahan JC, Case CC, Colburn RW, David S, Fawcett JW, Ferguson AR, ... Fischer I, et al. Large animal and primate models of spinal cord injury for the testing of novel therapies. Experimental Neurology. 269: 154-68. PMID 25902036 DOI: 10.1016/J.Expneurol.2015.04.008  0.386
2015 Ollivier-Lanvin K, Fischer I, Tom V, Houlé JD, Lemay MA. Either brain-derived neurotrophic factor or neurotrophin-3 only neurotrophin-producing grafts promote locomotor recovery in untrained spinalized cats. Neurorehabilitation and Neural Repair. 29: 90-100. PMID 24803493 DOI: 10.1177/1545968314532834  0.745
2014 Haas C, Fischer I. Transplanting neural progenitors to build a neuronal relay across the injured spinal cord. Neural Regeneration Research. 9: 1173-6. PMID 25206777 DOI: 10.4103/1673-5374.135321  0.761
2014 Jin Y, Bouyer J, Haas C, Fischer I. Behavioral and anatomical consequences of repetitive mild thoracic spinal cord contusion injury in the rat. Experimental Neurology. 257: 57-69. PMID 24786492 DOI: 10.1016/J.Expneurol.2014.04.016  0.697
2014 Medalha CC, Jin Y, Yamagami T, Haas C, Fischer I. Transplanting neural progenitors into a complete transection model of spinal cord injury. Journal of Neuroscience Research. 92: 607-18. PMID 24452691 DOI: 10.1002/Jnr.23340  0.793
2013 Bonner JF, Haas CJ, Fischer I. Preparation of neural stem cells and progenitors: neuronal production and grafting applications. Methods in Molecular Biology (Clifton, N.J.). 1078: 65-88. PMID 23975822 DOI: 10.1007/978-1-62703-640-5_7  0.834
2013 Haas C, Fischer I. Human astrocytes derived from glial restricted progenitors support regeneration of the injured spinal cord. Journal of Neurotrauma. 30: 1035-52. PMID 23635322 DOI: 10.1089/Neu.2013.2915  0.75
2013 Grous LC, Vernengo J, Jin Y, Himes BT, Shumsky JS, Fischer I, Lowman A. Implications of poly(N-isopropylacrylamide)-g-poly(ethylene glycol) with codissolved brain-derived neurotrophic factor injectable scaffold on motor function recovery rate following cervical dorsolateral funiculotomy in the rat. Journal of Neurosurgery. Spine. 18: 641-52. PMID 23581453 DOI: 10.3171/2013.3.Spine12874  0.685
2013 Saglam A, Perets A, Canver AC, Li HL, Kollins K, Cohen G, Fischer I, Lazarovici P, Lelkes PI. Angioneural crosstalk in scaffolds with oriented microchannels for regenerative spinal cord injury repair. Journal of Molecular Neuroscience : Mn. 49: 334-46. PMID 22878912 DOI: 10.1007/S12031-012-9863-9  0.684
2012 Blesch A, Fischer I, Tuszynski MH. Gene therapy, neurotrophic factors and spinal cord regeneration. Handbook of Clinical Neurology. 109: 563-74. PMID 23098737 DOI: 10.1016/B978-0-444-52137-8.00035-8  0.512
2012 Jin Y, Sura K, Fischer I. Differential effects of distinct central nervous system regions on cell migration and axonal extension of neural precursor transplants. Journal of Neuroscience Research. 90: 2065-73. PMID 22740505 DOI: 10.1002/Jnr.23099  0.637
2012 Ketschek AR, Haas C, Gallo G, Fischer I. The roles of neuronal and glial precursors in overcoming chondroitin sulfate proteoglycan inhibition. Experimental Neurology. 235: 627-37. PMID 22498104 DOI: 10.1016/J.Expneurol.2012.03.017  0.732
2012 Haas C, Neuhuber B, Yamagami T, Rao M, Fischer I. Phenotypic analysis of astrocytes derived from glial restricted precursors and their impact on axon regeneration. Experimental Neurology. 233: 717-32. PMID 22101004 DOI: 10.1016/J.Expneurol.2011.11.002  0.773
2011 Mitsui T, Neuhuber B, Fischer I. Acute administration of AMPA/Kainate blocker combined with delayed transplantation of neural precursors improves lower urinary tract function in spinal injured rats. Brain Research. 1418: 23-31. PMID 21937028 DOI: 10.1016/J.Brainres.2011.08.023  0.555
2011 Conova L, Vernengo J, Jin Y, Himes BT, Neuhuber B, Fischer I, Lowman A, Vernengo J, Jin Y, Himes BT, Neuhuber B, Fischer I, Lowman A. A pilot study of poly(N-isopropylacrylamide)-g-polyethylene glycol and poly(N-isopropylacrylamide)-g-methylcellulose branched copolymers as injectable scaffolds for local delivery of neurotrophins and cellular transplants into the injured spinal cord. Journal of Neurosurgery. Spine. 15: 594-604. PMID 21888482 DOI: 10.3171/2011.7.Spine11194  0.731
2011 Francis NL, Shanbhag MS, Fischer I, Wheatley MA. Influence of alginate cross-linking method on neurite response to microencapsulated neurotrophin-producing fibroblasts. Journal of Microencapsulation. 28: 353-62. PMID 21736520 DOI: 10.3109/02652048.2011.569765  0.472
2011 Jin Y, Ketschek A, Jiang Z, Smith G, Fischer I. Chondroitinase activity can be transduced by a lentiviral vector in vitro and in vivo Journal of Neuroscience Methods. 199: 208-213. PMID 21600922 DOI: 10.1016/J.Jneumeth.2011.05.007  0.467
2011 Lepore AC, O'Donnell J, Bonner JF, Paul C, Miller ME, Rauck B, Kushner RA, Rothstein JD, Fischer I, Maragakis NJ. Spatial and temporal changes in promoter activity of the astrocyte glutamate transporter GLT1 following traumatic spinal cord injury. Journal of Neuroscience Research. 89: 1001-17. PMID 21488085 DOI: 10.1002/Jnr.22624  0.823
2011 Bonner JF, Connors TM, Silverman WF, Kowalski DP, Lemay MA, Fischer I. Grafted neural progenitors integrate and restore synaptic connectivity across the injured spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4675-86. PMID 21430166 DOI: 10.1523/Jneurosci.4130-10.2011  0.845
2011 Jin Y, Neuhuber B, Singh A, Bouyer J, Lepore A, Bonner J, Himes T, Campanelli JT, Fischer I. Transplantation of human glial restricted progenitors and derived astrocytes into a contusion model of spinal cord injury. Journal of Neurotrauma. 28: 579-94. PMID 21222572 DOI: 10.1089/Neu.2010.1626  0.856
2010 Zhukareva V, Obrocka M, Houle JD, Fischer I, Neuhuber B. Secretion profile of human bone marrow stromal cells: donor variability and response to inflammatory stimuli. Cytokine. 50: 317-21. PMID 20185331 DOI: 10.1016/J.Cyto.2010.01.004  0.412
2010 See J, Bonner J, Neuhuber B, Fischer I. Neurite outgrowth of neural progenitors in presence of inhibitory proteoglycans. Journal of Neurotrauma. 27: 951-7. PMID 20102265 DOI: 10.1089/Neu.2009.1158  0.803
2010 Bonner JF, Blesch A, Neuhuber B, Fischer I. Promoting directional axon growth from neural progenitors grafted into the injured spinal cord. Journal of Neuroscience Research. 88: 1182-92. PMID 19908250 DOI: 10.1002/Jnr.22288  0.798
2009 Samdani AF, Paul C, Betz RR, Fischer I, Neuhuber B. Transplantation of human marrow stromal cells and mono-nuclear bone marrow cells into the injured spinal cord: a comparative study. Spine. 34: 2605-12. PMID 19881401 DOI: 10.1097/Brs.0B013E3181Bdca87  0.426
2009 Paul C, Samdani AF, Betz RR, Fischer I, Neuhuber B. Grafting of human bone marrow stromal cells into spinal cord injury: a comparison of delivery methods. Spine. 34: 328-34. PMID 19182705 DOI: 10.1097/Brs.0B013E31819403Ce  0.568
2009 Comolli N, Neuhuber B, Fischer I, Lowman A. In vitro analysis of PNIPAAm-PEG, a novel, injectable scaffold for spinal cord repair. Acta Biomaterialia. 5: 1046-55. PMID 19054721 DOI: 10.1016/J.Actbio.2008.10.008  0.714
2008 Neuhuber B, Barshinger AL, Paul C, Shumsky JS, Mitsui T, Fischer I. Stem cell delivery by lumbar puncture as a therapeutic alternative to direct injection into injured spinal cord. Journal of Neurosurgery. Spine. 9: 390-9. PMID 18939929 DOI: 10.3171/Spi.2008.9.10.390  0.53
2008 Neuhuber B, Swanger SA, Howard L, Mackay A, Fischer I. Effects of plating density and culture time on bone marrow stromal cell characteristics. Experimental Hematology. 36: 1176-85. PMID 18495329 DOI: 10.1016/J.Exphem.2008.03.019  0.74
2007 Boyce VS, Tumolo M, Fischer I, Murray M, Lemay MA. Neurotrophic factors promote and enhance locomotor recovery in untrained spinalized cats. Journal of Neurophysiology. 98: 1988-96. PMID 17652412 DOI: 10.1152/Jn.00391.2007  0.723
2006 Lepore AC, Neuhuber B, Connors TM, Han SS, Liu Y, Daniels MP, Rao MS, Fischer I. Long-term fate of neural precursor cells following transplantation into developing and adult CNS. Neuroscience. 142: 287-304. PMID 17120358 DOI: 10.1016/J.Neuroscience.2005.12.067  0.849
2006 Yoshihara H, Shumsky JS, Neuhuber B, Otsuka T, Fischer I, Murray M. Combining motor training with transplantation of rat bone marrow stromal cells does not improve repair or recovery in rats with thoracic contusion injuries. Brain Research. 1119: 65-75. PMID 17027672 DOI: 10.1016/J.Brainres.2006.08.080  0.49
2006 Lepore AC, Walczak P, Rao MS, Fischer I, Bulte JW. MR imaging of lineage-restricted neural precursors following transplantation into the adult spinal cord. Experimental Neurology. 201: 49-59. PMID 16764862 DOI: 10.1016/J.Expneurol.2006.03.032  0.82
2006 Park KI, Himes BT, Stieg PE, Tessler A, Fischer I, Snyder EY. Neural stem cells may be uniquely suited for combined gene therapy and cell replacement: Evidence from engraftment of Neurotrophin-3-expressing stem cells in hypoxic-ischemic brain injury. Experimental Neurology. 199: 179-90. PMID 16714016 DOI: 10.1016/J.Expneurol.2006.03.016  0.512
2006 Himes BT, Neuhuber B, Coleman C, Kushner R, Swanger SA, Kopen GC, Wagner J, Shumsky JS, Fischer I. Recovery of function following grafting of human bone marrow-derived stromal cells into the injured spinal cord. Neurorehabilitation and Neural Repair. 20: 278-96. PMID 16679505 DOI: 10.1177/1545968306286976  0.809
2006 Lepore AC, Neuhuber B, Connors TM, Han SS, Liu Y, Daniels MP, Rao MS, Fischer I. Long-term fate of neural precursor cells following transplantation into developing and adult CNS. Neuroscience. 139: 513-30. PMID 16458439 DOI: 10.1016/J.Neuroscience.2005.12.043  0.849
2006 Bakshi A, Barshinger AL, Swanger SA, Madhavani V, Shumsky JS, Neuhuber B, Fischer I. Lumbar puncture delivery of bone marrow stromal cells in spinal cord contusion: a novel method for minimally invasive cell transplantation. Journal of Neurotrauma. 23: 55-65. PMID 16430372 DOI: 10.1089/Neu.2006.23.55  0.802
2006 Mitsui T, Raghupathi R, Shumsky JS, Nonomura K, Fischer I, Murray M. 163: Acute Administration of AMPA Receptor Antagonist (NBQX) Combined with Delayed Transplantation of Neuronal and Glial Restricted Precursors (NRP/GRP) Improves Bladder Function in Spinal Injured Rats Journal of Urology. 175: 52-53. DOI: 10.1016/S0022-5347(18)32430-3  0.694
2006 Lepore A, Neuhuber B, Connors T, Han S, Liu Y, Daniels M, Rao M, Fischer I. Erratum to “Long-term fate of neural precursor cells following transplantation into developing and adult CNS” Neuroscience. 142: 285. DOI: 10.1016/J.Neuroscience.2005.12.068  0.742
2005 Swanger SA, Neuhuber B, Himes BT, Bakshi A, Fischer I. Analysis of allogeneic and syngeneic bone marrow stromal cell graft survival in the spinal cord. Cell Transplantation. 14: 775-86. PMID 16454352 DOI: 10.3727/000000005783982594  0.759
2005 Hayashi Y, Shumsky JS, Connors T, Otsuka T, Fischer I, Tessler A, Murray M. Immunosuppression with either cyclosporine a or FK506 supports survival of transplanted fibroblasts and promotes growth of host axons into the transplant after spinal cord injury. Journal of Neurotrauma. 22: 1267-81. PMID 16305315 DOI: 10.1089/Neu.2005.22.1267  0.499
2005 Nothias JM, Mitsui T, Shumsky JS, Fischer I, Antonacci MD, Murray M. Combined effects of neurotrophin secreting transplants, exercise, and serotonergic drug challenge improve function in spinal rats. Neurorehabilitation and Neural Repair. 19: 296-312. PMID 16263962 DOI: 10.1177/1545968305281209  0.465
2005 Mitsui T, Shumsky JS, Lepore AC, Murray M, Fischer I. Transplantation of neuronal and glial restricted precursors into contused spinal cord improves bladder and motor functions, decreases thermal hypersensitivity, and modifies intraspinal circuitry. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9624-36. PMID 16237167 DOI: 10.1523/Jneurosci.2175-05.2005  0.745
2005 Mitsui T, Fischer I, Shumsky JS, Murray M. Transplants of fibroblasts expressing BDNF and NT-3 promote recovery of bladder and hindlimb function following spinal contusion injury in rats. Experimental Neurology. 194: 410-31. PMID 16022868 DOI: 10.1016/J.Expneurol.2005.02.022  0.56
2005 Lepore AC, Bakshi A, Swanger SA, Rao MS, Fischer I. Neural precursor cells can be delivered into the injured cervical spinal cord by intrathecal injection at the lumbar cord. Brain Research. 1045: 206-16. PMID 15910779 DOI: 10.1016/J.Brainres.2005.03.050  0.859
2005 Lepore AC, Fischer I. Lineage-restricted neural precursors survive, migrate, and differentiate following transplantation into the injured adult spinal cord. Experimental Neurology. 194: 230-42. PMID 15899260 DOI: 10.1016/J.Expneurol.2005.02.020  0.804
2005 Anderson DK, Beattie M, Blesch A, Bresnahan J, Bunge M, Dietrich D, Dietz V, Dobkin B, Fawcett J, Fehlings M, Fischer I, Grossman R, Guest J, Hagg T, Hall ED, et al. Recommended guidelines for studies of human subjects with spinal cord injury. Spinal Cord. 43: 453-8. PMID 15824756 DOI: 10.1038/Sj.Sc.3101746  0.477
2005 Neuhuber B, Timothy Himes B, Shumsky JS, Gallo G, Fischer I. Axon growth and recovery of function supported by human bone marrow stromal cells in the injured spinal cord exhibit donor variations. Brain Research. 1035: 73-85. PMID 15713279 DOI: 10.1016/J.Brainres.2004.11.055  0.546
2005 Li P, Tessler A, Han SS, Fischer I, Rao MS, Selzer ME. Fate of immortalized human neuronal progenitor cells transplanted in rat spinal cord. Archives of Neurology. 62: 223-9. PMID 15710850 DOI: 10.1001/Archneur.62.2.223  0.813
2005 Tobias CA, Han SS, Shumsky JS, Kim D, Tumolo M, Dhoot NO, Wheatley MA, Fischer I, Tessler A, Murray M. Alginate encapsulated BDNF-producing fibroblast grafts permit recovery of function after spinal cord injury in the absence of immune suppression. Journal of Neurotrauma. 22: 138-56. PMID 15665609 DOI: 10.1089/Neu.2005.22.138  0.747
2005 Tint I, Fischer I, Black MM. Acute inactivation of MAP1b in growing sympathetic neurons destabilizes axonal microtubules Cell Motility and the Cytoskeleton. 60: 48-65. PMID 15573412 DOI: 10.1002/Cm.20045  0.365
2004 Lepore AC, Han SS, Tyler-Polsz CJ, Cai J, Rao MS, Fischer I. Differential fate of multipotent and lineage-restricted neural precursors following transplantation into the adult CNS. Neuron Glia Biology. 1: 113-26. PMID 16520830 DOI: 10.1017/S1740925X04000213  0.862
2004 Liu Y, Han SS, Wu Y, Tuohy TM, Xue H, Cai J, Back SA, Sherman LS, Fischer I, Rao MS. CD44 expression identifies astrocyte-restricted precursor cells. Developmental Biology. 276: 31-46. PMID 15531362 DOI: 10.1016/J.Ydbio.2004.08.018  0.719
2004 Bakshi A, Hunter C, Swanger S, Lepore A, Fischer I. Minimally invasive delivery of stem cells for spinal cord injury: advantages of the lumbar puncture technique. Journal of Neurosurgery. Spine. 1: 330-7. PMID 15478372 DOI: 10.3171/Spi.2004.1.3.0330  0.835
2004 Bakshi A, Fisher O, Dagci T, Himes BT, Fischer I, Lowman A. Mechanically engineered hydrogel scaffolds for axonal growth and angiogenesis after transplantation in spinal cord injury. Journal of Neurosurgery. Spine. 1: 322-9. PMID 15478371 DOI: 10.3171/Spi.2004.1.3.0322  0.725
2004 Dhoot NO, Tobias CA, Fischer I, Wheatley MA. Peptide-modified alginate surfaces as a growth permissive substrate for neurite outgrowth. Journal of Biomedical Materials Research. Part A. 71: 191-200. PMID 15376189 DOI: 10.1002/Jbm.A.30103  0.388
2004 Neuhuber B, Gallo G, Howard L, Kostura L, Mackay A, Fischer I. Reevaluation of in vitro differentiation protocols for bone marrow stromal cells: disruption of actin cytoskeleton induces rapid morphological changes and mimics neuronal phenotype. Journal of Neuroscience Research. 77: 192-204. PMID 15211586 DOI: 10.1002/Jnr.20147  0.424
2004 Murray M, Fischer I, Smeraski C, Tessler A, Giszter S. Towards a definition of recovery of function. Journal of Neurotrauma. 21: 405-13. PMID 15115590 DOI: 10.1089/089771504323004557  0.529
2004 Han SS, Liu Y, Tyler-Polsz C, Rao MS, Fischer I. Transplantation of glial-restricted precursor cells into the adult spinal cord: survival, glial-specific differentiation, and preferential migration in white matter. Glia. 45: 1-16. PMID 14648541 DOI: 10.1002/Glia.10282  0.832
2004 Bakshi A, Mitsui T, Swanger S, Sabol M, Shumsky J, Fischer I. 776 Marrow Stromal Cells Delivered via Lumbar Puncture Home toward Spinal Cord Contusion and Cause Repair Neurosurgery. 55: 478-478. DOI: 10.1097/00006123-200408000-00112  0.779
2003 Emery DL, Royo NC, Fischer I, Saatman KE, McIntosh TK. Plasticity following injury to the adult central nervous system: is recapitulation of a developmental state worth promoting? Journal of Neurotrauma. 20: 1271-92. PMID 14748977 DOI: 10.1089/089771503322686085  0.427
2003 Tobias CA, Shumsky JS, Shibata M, Tuszynski MH, Fischer I, Tessler A, Murray M. Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration. Experimental Neurology. 184: 97-113. PMID 14637084 DOI: 10.1016/S0014-4886(03)00394-7  0.575
2003 Han SSW, Kang DY, Mujtaba T, Rao MS, Fischer I. ErratumErratum to “grafted lineage-restricted precursors differentiate exclusively into neurons in the adult spinal cord”: [Exp. Neurol. 177 (2002) 360–375]☆,☆☆ Experimental Neurology. 180: 1-2. DOI: 10.1016/S0014-4886(03)00005-0  0.648
2002 Murray M, Kim D, Liu Y, Tobias C, Tessler A, Fischer I. Transplantation of genetically modified cells contributes to repair and recovery from spinal injury. Brain Research. Brain Research Reviews. 40: 292-300. PMID 12589927 DOI: 10.1016/S0165-0173(02)00211-4  0.518
2002 Liu Y, Himes BT, Murray M, Tessler A, Fischer I. Grafts of BDNF-producing fibroblasts rescue axotomized rubrospinal neurons and prevent their atrophy. Experimental Neurology. 178: 150-64. PMID 12504875 DOI: 10.1006/Exnr.2002.7977  0.562
2002 Jin Y, Fischer I, Tessler A, Houle JD. Transplants of fibroblasts genetically modified to express BDNF promote axonal regeneration from supraspinal neurons following chronic spinal cord injury. Experimental Neurology. 177: 265-75. PMID 12429228 DOI: 10.1006/Exnr.2002.7980  0.566
2002 Han SS, Kang DY, Mujtaba T, Rao MS, Fischer I. Grafted lineage-restricted precursors differentiate exclusively into neurons in the adult spinal cord. Experimental Neurology. 177: 360-75. PMID 12429183 DOI: 10.1006/Exnr.2002.7995  0.822
2002 Soares S, von Boxberg Y, Lombard MC, Ravaille-Veron M, Fischer I, Eyer J, Nothias F. Phosphorylated MAP1B is induced in central sprouting of primary afferents in response to peripheral injury but not in response to rhizotomy. The European Journal of Neuroscience. 16: 593-606. PMID 12270035 DOI: 10.1046/J.1460-9568.2002.02126.X  0.392
2002 Wu YY, Mujtaba T, Han SS, Fischer I, Rao MS. Isolation of a glial-restricted tripotential cell line from embryonic spinal cord cultures. Glia. 38: 65-79. PMID 11921204 DOI: 10.1002/Glia.10049  0.798
2002 Mujtaba T, Han SS, Fischer I, Sandgren EP, Rao MS. Stable expression of the alkaline phosphatase marker gene by neural cells in culture and after transplantation into the CNS using cells derived from a transgenic rat. Experimental Neurology. 174: 48-57. PMID 11869033 DOI: 10.1006/Exnr.2001.7847  0.781
2001 Himes BT, Liu Y, Solowska JM, Snyder EY, Fischer I, Tessler A. Transplants of cells genetically modified to express neurotrophin-3 rescue axotomized Clarke's nucleus neurons after spinal cord hemisection in adult rats. Journal of Neuroscience Research. 65: 549-64. PMID 11550223 DOI: 10.1002/Jnr.1185  0.571
2001 Murray M, Fischer I. Transplantation and gene therapy: Combined approaches for repair of spinal cord injury Neuroscientist. 7: 28-41. PMID 11486342 DOI: 10.1177/107385840100700107  0.584
2001 Tobias CA, Dhoot NO, Wheatley MA, Tessler A, Murray M, Fischer I. Grafting of encapsulated BDNF-producing fibroblasts into the injured spinal cord without immune suppression in adult rats. Journal of Neurotrauma. 18: 287-301. PMID 11284549 DOI: 10.1089/08977150151070937  0.576
2001 Deng W, Obrocka M, Fischer I, Prockop DJ. In vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP Biochemical and Biophysical Research Communications. 282: 148-152. PMID 11263984 DOI: 10.1006/Bbrc.2001.4570  0.423
2001 Hormigo A, McCarthy M, Nothias JM, Hasegawa K, Huang W, Friedlander DR, Fischer I, Fishell G, Grumet M. Radial glial cell line C6-R integrates preferentially in adult white matter and facilitates migration of coimplanted neurons in vivo. Experimental Neurology. 168: 310-22. PMID 11259119 DOI: 10.1006/Exnr.2000.7620  0.443
2000 Jin Y, Tessler A, Fischer I, Houle JD. Fibroblasts genetically modified to produce BDNF support regrowth of chronically injured serotonergic axons. Neurorehabilitation and Neural Repair. 14: 311-7. PMID 11402881 DOI: 10.1177/154596830001400407  0.546
2000 Liu Y, Murray M, Tessler A, Fischer I. Grafting of genetically modified fibroblasts into the injured spinal cord. Progress in Brain Research. 128: 309-19. PMID 11105690 DOI: 10.1016/S0079-6123(00)28028-X  0.517
2000 Fischer I. Candidate cells for transplantation into the injured CNS Progress in Brain Research. 128: 253-257. PMID 11105684 DOI: 10.1016/S0079-6123(00)28022-9  0.459
2000 Tobias CA, Kim D, Fischer I. Improved recombinant retroviral titers utilizing trichostatin A. Biotechniques. 29: 884-90. PMID 11056820 DOI: 10.2144/00294Rr05  0.349
2000 Chow SY, Moul J, Tobias CA, Himes BT, Liu Y, Obrocka M, Hodge L, Tessler A, Fischer I. Characterization and intraspinal grafting of EGF/bFGF-dependent neurospheres derived from embryonic rat spinal cord. Brain Research. 874: 87-106. PMID 10960593 DOI: 10.1016/S0006-8993(00)02443-4  0.64
2000 Ma D, Connors T, Nothias F, Fischer I. Regulation of the expression and phosphorylation of microtubule-associated protein 1B during regeneration of adult dorsal root ganglion neurons. Neuroscience. 99: 157-170. PMID 10924960 DOI: 10.1016/S0306-4522(00)00141-X  0.348
2000 Emery DL, Raghupathi R, Saatman KE, Fischer I, Grady MS, McIntosh TK. Bilateral growth-related protein expression suggests a transient increase in regenerative potential following brain trauma. The Journal of Comparative Neurology. 424: 521-31. PMID 10906717 DOI: 10.1002/1096-9861(20000828)424:3<521::Aid-Cne9>3.0.Co;2-8  0.619
2000 Han SS, Fischer I. Neural stem cells and gene therapy: prospects for repairing the injured spinal cord. Jama. 283: 2300-1. PMID 10807395 DOI: 10.1001/Jama.283.17.2300-Jms0503-5-1  0.735
2000 Gordon-Weeks PR, Fischer I. MAP1B expression and microtubule stability in growing and regenerating axons. Microscopy Research and Technique. 48: 63-74. PMID 10649507 DOI: 10.1002/(Sici)1097-0029(20000115)48:2<63::Aid-Jemt2>3.0.Co;2-1  0.356
1999 Liu Y, Himes BT, Solowska J, Moul J, Chow SY, Park KI, Tessler A, Murray M, Snyder EY, Fischer I. Intraspinal delivery of neurotrophin-3 using neural stem cells genetically modified by recombinant retrovirus. Experimental Neurology. 158: 9-26. PMID 10448414 DOI: 10.1006/Exnr.1999.7079  0.581
1999 Liu Y, Kim D, Himes BT, Chow SY, Schallert T, Murray M, Tessler A, Fischer I. Transplants of fibroblasts genetically modified to express BDNF promote regeneration of adult rat rubrospinal axons and recovery of forelimb function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4370-87. PMID 10341240 DOI: 10.1523/Jneurosci.19-11-04370.1999  0.538
1999 Ma D, Chow S, Obrocka M, Connors T, Fischer I. Induction of microtubule-associated protein 1B expression in Schwann cells during nerve regeneration Brain Research. 823: 141-153. PMID 10095020 DOI: 10.1016/S0006-8993(99)01148-8  0.435
1998 Tint I, Slaughter T, Fischer I, Black MM. Acute inactivation of tau has no effect on dynamics of microtubules in growing axons of cultured sympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 8660-73. PMID 9786973 DOI: 10.1523/Jneurosci.18-21-08660.1998  0.366
1998 Soares S, Fischer I, Ravaille-Veron M, Vincent JD, Nothias F. Induction of MAP1B phosphorylation in target-deprived afferent fibers after kainic acid lesion in the adult rat. The Journal of Comparative Neurology. 396: 193-210. PMID 9634142 DOI: 10.1002/(Sici)1096-9861(19980629)396:2<193::Aid-Cne5>3.0.Co;2-W  0.365
1998 Liu Y, Himes BT, Tryon B, Moul J, Chow SY, Jin H, Murray M, Tessler A, Fischer I. Intraspinal grafting of fibroblasts genetically modified by recombinant adenoviruses. Neuroreport. 9: 1075-9. PMID 9601670 DOI: 10.1097/00001756-199804200-00021  0.438
1997 Liu Y, Himes BT, Moul J, Huang W, Chow SY, Tessler A, Fischer I. Application of recombinant adenovirus for in vivo gene delivery to spinal cord. Brain Research. 768: 19-29. PMID 9369296 DOI: 10.1016/S0006-8993(97)00587-8  0.544
1997 Nunez J, Fischer I. Microtubule-Associated Proteins (MAPs) in the Peripheral Nervous System during Development and Regeneration Journal of Molecular Neuroscience. 8: 207-222. PMID 9297633 DOI: 10.1007/Bf02736834  0.462
1997 Ma D, Nothias F, Boyne LJ, Fischer I. Differential regulation of microtubule-associated protein 1B (MAP1B) in rat CNS and PNS during development. Journal of Neuroscience Research. 49: 319-332. PMID 9260743 DOI: 10.1002/(Sici)1097-4547(19970801)49:3<319::Aid-Jnr7>3.0.Co;2-F  0.514
1996 Boyne LJ, Fischer I, Shea TB. Role of vimentin in early stages of neuritogenesis in cultured hippocampal neurons. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 14: 739-48. PMID 8960981 DOI: 10.1016/S0736-5748(96)00053-6  0.366
1996 Hoffman JR, Boyne LJ, Levitt P, Fischer I. Short exposure to methylazoxymethanol causes a long-term inhibition of axonal outgrowth from cultured embryonic rat hippocampal neurons Journal of Neuroscience Research. 46: 349-359. PMID 8933374 DOI: 10.1002/(Sici)1097-4547(19961101)46:3<349::Aid-Jnr8>3.0.Co;2-K  0.42
1996 Nothias F, Fischer I, Murray M, Mirman S, Vincent JD. Expression of a phosphorylated isoform of MAP1B is maintained in adult central nervous system areas that retain capacity for structural plasticity. The Journal of Comparative Neurology. 368: 317-34. PMID 8725342 DOI: 10.1002/(Sici)1096-9861(19960506)368:3<317::Aid-Cne1>3.0.Co;2-8  0.364
1996 Black MM, Slaughter T, Moshiach S, Obrocka M, Fischer I. Tau is enriched on dynamic microtubules in the distal region of growing axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 3601-19. PMID 8642405 DOI: 10.1523/Jneurosci.16-11-03601.1996  0.314
1996 Book AA, Fischer I, Yu XJ, Iannuzzelli P, Murphy EH. Altered expression of microtubule-associated proteins in cat trochlear motoneurons after peripheral and central lesions of the trochlear nerve. Experimental Neurology. 138: 214-26. PMID 8620920 DOI: 10.1006/Exnr.1996.0060  0.376
1996 Edelmann W, Zervas M, Costello P, Roback L, Fischer I, Hammarback JA, Cowan N, Davies P, Wainer B, Kucherlapati R. Neuronal abnormalities in microtubule-associated protein 1B mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 93: 1270-5. PMID 8577753 DOI: 10.1073/Pnas.93.3.1270  0.332
1996 Liu D, Fischer I. Two Alternative Promoters Direct Neuron-Specific Expression of the Rat Microtubule-Associated Protein 1B Gene The Journal of Neuroscience. 16: 5026-5036. DOI: 10.1523/Jneurosci.16-16-05026.1996  0.346
1995 Pimenta AF, Zhukareva V, Barbe MF, Reinoso BS, Grimley C, Henzel W, Fischer I, Levitt P. The limbic system-associated membrane protein is an Ig superfamily member that mediates selective neuronal growth and axon targeting. Neuron. 15: 287-97. PMID 7646886 DOI: 10.1016/0896-6273(95)90034-9  0.349
1995 Nothias F, Boyne L, Murray M, Tessler A, Fischer I. The expression and distribution of tau proteins and messenger RNA in rat dorsal root ganglion neurons during development and regeneration. Neuroscience. 66: 707-19. PMID 7644032 DOI: 10.1016/0306-4522(94)00598-Y  0.383
1995 Boyne LJ, Martin K, Hockfield S, Fischer I. Expression and distribution of phosphorylated MAP1B in growing axons of cultured hippocampal neurons. Journal of Neuroscience Research. 40: 439-50. PMID 7616605 DOI: 10.1002/Jnr.490400403  0.376
1995 Boyne LJ, Tessler A, Murray M, Fischer I. Distribution of Big tau in the central nervous system of the adult and developing rat. The Journal of Comparative Neurology. 358: 279-93. PMID 7560287 DOI: 10.1002/Cne.903580209  0.459
1994 Black MM, Slaughter T, Fischer I. Microtubule-associated protein 1b (MAP1b) is concentrated in the distal region of growing axons Journal of Neuroscience. 14: 857-870. PMID 8301365 DOI: 10.1523/Jneurosci.14-02-00857.1994  0.328
1994 Qian J, Wang H, Fischer I, Friedman E, Levitt P. Involvement of protein kinase C in the axonal growth-promoting effect on spinal cord neurons by target-derived astrocytes. Journal of Neurobiology. 25: 1593-1612. PMID 7861122 DOI: 10.1002/Neu.480251211  0.484
1992 Sapirstein VS, Nolan CE, Stadler II, Fischer I. Expression of plasmolipin in the developing rat brain. Journal of Neuroscience Research. 31: 96-102. PMID 1535379 DOI: 10.1002/Jnr.490310114  0.366
1992 Shea TB, Beermann ML, Nixon RA, Fischer I. Microtubule-associated protein tau is required for axonal neurite elaboration by neuroblastoma cells. Journal of Neuroscience Research. 32: 363-74. PMID 1433385 DOI: 10.1002/Jnr.490320308  0.345
1991 Fischer I, Richter-Landsberg C, Safaei R. Regulation of microtubule associated protein 2 (MAP2) expression by nerve growth factor in PC12 cells. Experimental Cell Research. 194: 195-201. PMID 2026175 DOI: 10.1016/0014-4827(91)90354-W  0.302
1991 Pennypacker K, Fischer I, Levitt P. Early in vitro genesis and differentiation of axons and dendrites by hippocampal neurons analyzed quantitatively with neurofilament-H and microtubule-associated protein 2 antibodies. Experimental Neurology. 111: 25-35. PMID 1898595 DOI: 10.1016/0014-4886(91)90047-G  0.339
1991 Sapirstein VS, Nolan CE, Fischer I, Cochary E, Blau S, Flynn CJ. The phylogenic expression of plasmolipin in the vertebrate nervous system. Neurochemical Research. 16: 123-8. PMID 1881515 DOI: 10.1007/Bf00965699  0.302
1991 Fischer I, Cochary EF, Konola JT, Romano‐Clarke G. Expression of plasmolipin in oligodendrocytes. Journal of Neuroscience Research. 28: 81-89. PMID 1710283 DOI: 10.1002/Jnr.490280108  0.34
1991 Fischer I, Romano-Clarke G. Association of microtubule-associated protein (MAP1B) with growing axons in cultured hippocampal neurons Molecular and Cellular Neuroscience. 2: 39-51. DOI: 10.1016/1044-7431(91)90038-P  0.398
1990 Fischer I, Konola J, Cochary E. Microtubule associated protein (MAP1B) is present in cultured oligodendrocytes and co‐localizes with tubulin Journal of Neuroscience Research. 27: 112-124. PMID 2254953 DOI: 10.1002/Jnr.490270117  0.339
1986 Fischer I, Shea TB, Sapirstein VS, Kosik KS. Expression and distribution of microtubule-associated protein 2 (MAP2) in neuroblastoma and primary neuronal cells. Brain Research. 390: 99-109. PMID 3512042 DOI: 10.1016/0165-3806(86)90156-2  0.401
1986 Shea TB, Fischer I, Sapirstein V. Expression of a plasma membrane proteolipid during differentiation of neuronal and glial cells in primary culture. Journal of Neurochemistry. 47: 697-706. PMID 3016181 DOI: 10.1111/J.1471-4159.1986.Tb00668.X  0.333
1986 Fischer I, Shea TS, Sapirstein VS. Induction of lysosomal glycosidases by dibutyryl cAMP in neuroblastoma cells. Neurochemical Research. 11: 589-598. PMID 2425267 DOI: 10.1007/Bf00965328  0.357
1985 Shea TB, Fischer I, Sapirstein VS. Effect of retinoic acid on growth and morphological differentiation of mouse NB2a neuroblastoma cells in culture. Brain Research. 353: 307-14. PMID 2994850 DOI: 10.1016/0165-3806(85)90220-2  0.305
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