Tracy K. McIntosh - Publications

Affiliations: 
Media Neuroconsultants 

253 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Lifshitz J, Rowe RK, Griffiths DR, Evilsizor MN, Thomas TC, Adelson PD, McIntosh TK. Clinical relevance of midline fluid percussion brain injury: Acute deficits, chronic morbidities and the utility of biomarkers. Brain Injury. 1-9. PMID 27712117 DOI: 10.1080/02699052.2016.1193628  0.805
2012 Tomasevic G, Laurer HL, Mattiasson G, van Steeg H, Wieloch T, McIntosh TK. Delayed neuromotor recovery and increased memory acquisition dysfunction following experimental brain trauma in mice lacking the DNA repair gene XPA. Journal of Neurosurgery. 116: 1368-78. PMID 22462511 DOI: 10.3171/2012.2.Jns11888  0.45
2010 Tomasevic G, Raghupathi R, Scherbel U, Wieloch T, McIntosh TK. Deletion of the p53 tumor suppressor gene improves neuromotor function but does not attenuate regional neuronal cell loss following experimental brain trauma in mice. Journal of Neuroscience Research. 88: 3414-23. PMID 20890990 DOI: 10.1002/Jnr.22491  0.649
2010 HÃ¥nell A, Clausen F, Björk M, Jansson K, Philipson O, Nilsson LN, Hillered L, Weinreb PH, Lee D, McIntosh TK, Gimbel DA, Strittmatter SM, Marklund N. Genetic deletion and pharmacological inhibition of Nogo-66 receptor impairs cognitive outcome after traumatic brain injury in mice. Journal of Neurotrauma. 27: 1297-309. PMID 20486800 DOI: 10.1089/Neu.2009.1255  0.777
2009 Marklund N, Morales D, Clausen F, HÃ¥nell A, Kiwanuka O, Pitkänen A, Gimbel DA, Philipson O, Lannfelt L, Hillered L, Strittmatter SM, McIntosh TK. Functional outcome is impaired following traumatic brain injury in aging Nogo-A/B-deficient mice. Neuroscience. 163: 540-51. PMID 19555742 DOI: 10.1016/J.Neuroscience.2009.06.042  0.75
2008 Conte V, Raghupathi R, Watson DJ, Fujimoto S, Royo NC, Marklund N, Stocchetti N, McIntosh TK. TrkB gene transfer does not alter hippocampal neuronal loss and cognitive deficits following traumatic brain injury in mice. Restorative Neurology and Neuroscience. 26: 45-56. PMID 18431005  0.755
2007 Marklund N, Bareyre FM, Royo NC, Thompson HJ, Mir AK, Grady MS, Schwab ME, McIntosh TK. Cognitive outcome following brain injury and treatment with an inhibitor of Nogo-A in association with an attenuated downregulation of hippocampal growth-associated protein-43 expression. Journal of Neurosurgery. 107: 844-53. PMID 17937233 DOI: 10.3171/Jns-07/10/0844  0.796
2007 Keck CA, Thompson HJ, Pitkänen A, LeBold DG, Morales DM, Plevy JB, Puri R, Zhao B, Dichter M, McIntosh TK. The novel antiepileptic agent RWJ-333369-A, but not its analog RWJ-333369, reduces regional cerebral edema without affecting neurobehavioral outcome or cell death following experimental traumatic brain injury. Restorative Neurology and Neuroscience. 25: 77-90. PMID 17726266  0.416
2006 Thompson HJ, Marklund N, LeBold DG, Morales DM, Keck CA, Vinson M, Royo NC, Grundy R, McIntosh TK. Tissue sparing and functional recovery following experimental traumatic brain injury is provided by treatment with an anti-myelin-associated glycoprotein antibody. The European Journal of Neuroscience. 24: 3063-72. PMID 17156367 DOI: 10.1111/J.1460-9568.2006.05197.X  0.648
2006 Johnson VE, Murray L, Raghupathi R, Stewart J, Nicoll JA, MacKinnon MA, McIntosh TK, Graham DI. No evidence for the presence of apolipoprotein epsilon4, interleukin-lalpha allele 2 and interleukin-1beta allele 2 cause an increase in programmed cell death following traumatic brain injury in humans. Clinical Neuropathology. 25: 255-64. PMID 17140155  0.608
2006 Morales D, McIntosh T, Conte V, Fujimoto S, Graham D, Grady MS, Stein SC. Impaired fibrinolysis and traumatic brain injury in mice. Journal of Neurotrauma. 23: 976-84. PMID 16774481 DOI: 10.1089/Neu.2006.23.976  0.68
2006 Maxwell WL, MacKinnon MA, Smith DH, McIntosh TK, Graham DI. Thalamic nuclei after human blunt head injury. Journal of Neuropathology and Experimental Neurology. 65: 478-88. PMID 16772871 DOI: 10.1097/01.Jnen.0000229241.28619.75  0.471
2006 Marklund N, Bakshi A, Castelbuono DJ, Conte V, McIntosh TK. Evaluation of pharmacological treatment strategies in traumatic brain injury. Current Pharmaceutical Design. 12: 1645-80. PMID 16729876 DOI: 10.2174/138161206776843340  0.631
2006 Thompson HJ, LeBold DG, Marklund N, Morales DM, Hagner AP, McIntosh TK. Cognitive evaluation of traumatically brain-injured rats using serial testing in the Morris water maze. Restorative Neurology and Neuroscience. 24: 109-14. PMID 16720946  0.619
2006 Bakshi A, Shimizu S, Keck CA, Cho S, LeBold DG, Morales D, Arenas E, Snyder EY, Watson DJ, McIntosh TK. Neural progenitor cells engineered to secrete GDNF show enhanced survival, neuronal differentiation and improve cognitive function following traumatic brain injury. The European Journal of Neuroscience. 23: 2119-34. PMID 16630059 DOI: 10.1111/J.1460-9568.2006.04743.X  0.468
2006 Royo NC, Conte V, Saatman KE, Shimizu S, Belfield CM, Soltesz KM, Davis JE, Fujimoto ST, McIntosh TK. Hippocampal vulnerability following traumatic brain injury: a potential role for neurotrophin-4/5 in pyramidal cell neuroprotection. The European Journal of Neuroscience. 23: 1089-102. PMID 16553773 DOI: 10.1111/J.1460-9568.2006.04642.X  0.718
2006 Dubreuil CI, Marklund N, Deschamps K, McIntosh TK, McKerracher L. Activation of Rho after traumatic brain injury and seizure in rats. Experimental Neurology. 198: 361-9. PMID 16448651 DOI: 10.1016/J.Expneurol.2005.12.002  0.703
2006 Yi JH, Hoover R, McIntosh TK, Hazell AS. Early, transient increase in complexin I and complexin II in the cerebral cortex following traumatic brain injury is attenuated by N-acetylcysteine. Journal of Neurotrauma. 23: 86-96. PMID 16430375 DOI: 10.1089/Neu.2006.23.86  0.478
2006 Schütz C, Stover JF, Thompson HJ, Hoover RC, Morales DM, Schouten JW, McMillan A, Soltesz K, Motta M, Spangler Z, Neugebauer E, McIntosh TK. Acute, transient hemorrhagic hypotension does not aggravate structural damage or neurologic motor deficits but delays the long-term cognitive recovery following mild to moderate traumatic brain injury. Critical Care Medicine. 34: 492-501. PMID 16424733 DOI: 10.1097/01.Ccm.0000198326.32049.7F  0.609
2006 Marklund N, Fulp CT, Shimizu S, Puri R, McMillan A, Strittmatter SM, McIntosh TK. Selective temporal and regional alterations of Nogo-A and small proline-rich repeat protein 1A (SPRR1A) but not Nogo-66 receptor (NgR) occur following traumatic brain injury in the rat. Experimental Neurology. 197: 70-83. PMID 16321384 DOI: 10.1016/J.Expneurol.2005.08.029  0.705
2006 Lifshitz J, Janmey PA, McIntosh TK. Photon correlation spectroscopy of brain mitochondrial populations: application to traumatic brain injury. Experimental Neurology. 197: 318-29. PMID 16289540 DOI: 10.1016/J.Expneurol.2005.10.002  0.552
2006 Yoshiyama Y, Kunihiro U, Higuchi M, McIntosh T, Lee VM, Trojanowski JQ. P3-290: Enhanced tau pathology, cerebral atrophy and iron deposition induced by repetitive mild brain injury in a tau transgenic mouse Alzheimer's & Dementia. 2: S461-S461. DOI: 10.1016/J.Jalz.2006.05.1559  0.425
2005 Zhang C, Saatman KE, Royo NC, Soltesz KM, Millard M, Schouten JW, Motta M, Hoover RC, McMillan A, Watson DJ, Lee VM, Trojanowski JQ, McIntosh TK. Delayed transplantation of human neurons following brain injury in rats: a long-term graft survival and behavior study. Journal of Neurotrauma. 22: 1456-74. PMID 16379583 DOI: 10.1089/Neu.2005.22.1456  0.685
2005 Bakshi A, Keck CA, Koshkin VS, LeBold DG, Siman R, Snyder EY, McIntosh TK. Caspase-mediated cell death predominates following engraftment of neural progenitor cells into traumatically injured rat brain. Brain Research. 1065: 8-19. PMID 16309635 DOI: 10.1016/j.brainres.2005.09.059  0.309
2005 Morales DM, Marklund N, Lebold D, Thompson HJ, Pitkanen A, Maxwell WL, Longhi L, Laurer H, Maegele M, Neugebauer E, Graham DI, Stocchetti N, McIntosh TK. Experimental models of traumatic brain injury: do we really need to build a better mousetrap? Neuroscience. 136: 971-89. PMID 16242846 DOI: 10.1016/J.Neuroscience.2005.08.030  0.648
2005 Yoshiyama Y, Uryu K, Higuchi M, Longhi L, Hoover R, Fujimoto S, McIntosh T, Lee VM, Trojanowski JQ. Enhanced neurofibrillary tangle formation, cerebral atrophy, and cognitive deficits induced by repetitive mild brain injury in a transgenic tauopathy mouse model. Journal of Neurotrauma. 22: 1134-41. PMID 16238489 DOI: 10.1089/Neu.2005.22.1134  0.408
2005 Emery DL, Fulp CT, Saatman KE, Schütz C, Neugebauer E, McIntosh TK. Newly born granule cells in the dentate gyrus rapidly extend axons into the hippocampal CA3 region following experimental brain injury. Journal of Neurotrauma. 22: 978-88. PMID 16156713 DOI: 10.1089/Neu.2005.22.978  0.789
2005 Maegele M, Lippert-Gruener M, Ester-Bode T, Sauerland S, Schäfer U, Molcanyi M, Molcany M, Lefering R, Bouillon B, Neiss WF, Angelov DN, Klug N, McIntosh TK, Neugebauer EA. Reversal of neuromotor and cognitive dysfunction in an enriched environment combined with multimodal early onset stimulation after traumatic brain injury in rats. Journal of Neurotrauma. 22: 772-82. PMID 16004580 DOI: 10.1089/Neu.2005.22.772  0.493
2005 Lenzlinger PM, Shimizu S, Marklund N, Thompson HJ, Schwab ME, Saatman KE, Hoover RC, Bareyre FM, Motta M, Luginbuhl A, Pape R, Clouse AK, Morganti-Kossmann C, McIntosh TK. Delayed inhibition of Nogo-A does not alter injury-induced axonal sprouting but enhances recovery of cognitive function following experimental traumatic brain injury in rats. Neuroscience. 134: 1047-56. PMID 15979242 DOI: 10.1016/J.Neuroscience.2005.04.048  0.824
2005 Marklund N, Keck C, Hoover R, Soltesz K, Millard M, LeBold D, Spangler Z, Banning A, Benson J, McIntosh TK. Administration of monoclonal antibodies neutralizing the inflammatory mediators tumor necrosis factor alpha and interleukin -6 does not attenuate acute behavioral deficits following experimental traumatic brain injury in the rat. Restorative Neurology and Neuroscience. 23: 31-42. PMID 15846030  0.515
2005 Maegele M, Riess P, Sauerland S, Bouillon B, Hess S, McIntosh TK, Mautes A, Brockmann M, Koebke J, Knifka J, Neugebauer EA. Characterization of a new rat model of experimental combined neurotrauma. Shock (Augusta, Ga.). 23: 476-81. PMID 15834316 DOI: 10.1097/01.Shk.0000159929.87737.5C  0.433
2005 Longhi L, Saatman KE, Fujimoto S, Raghupathi R, Meaney DF, Davis J, McMillan B S A, Conte V, Laurer HL, Stein S, Stocchetti N, McIntosh TK. Temporal window of vulnerability to repetitive experimental concussive brain injury. Neurosurgery. 56: 364-74; discussion 3. PMID 15670384 DOI: 10.1227/01.Neu.0000149008.73513.44  0.779
2005 Thompson HJ, Lifshitz J, Marklund N, Grady MS, Graham DI, Hovda DA, McIntosh TK. Lateral fluid percussion brain injury: a 15-year review and evaluation. Journal of Neurotrauma. 22: 42-75. PMID 15665602 DOI: 10.1089/Neu.2005.22.42  0.829
2005 Thompson HJ, Hoover RC, Tkacs NC, Saatman KE, McIntosh TK. Development of posttraumatic hyperthermia after traumatic brain injury in rats is associated with increased periventricular inflammation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 163-76. PMID 15647747 DOI: 10.1038/Sj.Jcbfm.9600008  0.769
2005 Boockvar JA, Schouten J, Royo N, Millard M, Spangler Z, Castelbuono D, Snyder E, O'Rourke D, McIntosh T. Experimental traumatic brain injury modulates the survival, migration, and terminal phenotype of transplanted epidermal growth factor receptor-activated neural stem cells Neurosurgery. 56: 163-171. PMID 15617599 DOI: 10.1227/01.Neu.0000145866.25433.Ff  0.389
2005 Fujimoto ST, Longhi L, Saatman KE, Conte V, Stocchetti N, McIntosh TK. Corrigendum to “Motor and cognitive function evaluation following experimental traumatic brain injury” [Neurosci. Biobehav. Rev. 28 (2004) 365–378] Neuroscience & Biobehavioral Reviews. 28: 877. DOI: 10.1016/J.Neubiorev.2004.10.002  0.602
2005 Pitkänen A, Longhi L, Marklund N, Morales DM, McIntosh TK. Neurodegeneration and neuroprotective strategies after traumatic brain injury Drug Discovery Today: Disease Mechanisms. 2: 409-418. DOI: 10.1016/J.Ddmec.2005.11.011  0.562
2004 Lifshitz J, Sullivan PG, Hovda DA, Wieloch T, McIntosh TK. Mitochondrial damage and dysfunction in traumatic brain injury. Mitochondrion. 4: 705-13. PMID 16120426 DOI: 10.1016/J.Mito.2004.07.021  0.635
2004 Longhi L, Watson DJ, Saatman KE, Thompson HJ, Zhang C, Fujimoto S, Royo N, Castelbuono D, Raghupathi R, Trojanowski JQ, Lee VM, Wolfe JH, Stocchetti N, McIntosh TK. Ex vivo gene therapy using targeted engraftment of NGF-expressing human NT2N neurons attenuates cognitive deficits following traumatic brain injury in mice. Journal of Neurotrauma. 21: 1723-36. PMID 15684764 DOI: 10.1089/Neu.2004.21.1723  0.803
2004 Schouten JW, Fulp CT, Royo NC, Saatman KE, Watson DJ, Snyder EY, Trojanowski JQ, Prockop DJ, Maas AI, McIntosh TK. A review and rationale for the use of cellular transplantation as a therapeutic strategy for traumatic brain injury. Journal of Neurotrauma. 21: 1501-38. PMID 15684646 DOI: 10.1089/Neu.2004.21.1501  0.669
2004 Maxwell WL, Pennington K, MacKinnon MA, Smith DH, McIntosh TK, Wilson JT, Graham DI. Differential responses in three thalamic nuclei in moderately disabled, severely disabled and vegetative patients after blunt head injury. Brain : a Journal of Neurology. 127: 2470-8. PMID 15456707 DOI: 10.1093/Brain/Awh294  0.525
2004 Fujimoto ST, Longhi L, Saatman KE, Conte V, Stocchetti N, McIntosh TK. Motor and cognitive function evaluation following experimental traumatic brain injury. Neuroscience and Biobehavioral Reviews. 28: 365-78. PMID 15341032 DOI: 10.1016/J.Neubiorev.2004.06.002  0.685
2004 Lenzlinger PM, Saatman KE, Hoover RC, Cheney JA, Bareyre FM, Raghupathi R, Arnold LD, McIntosh TK. Inhibition of vascular endothelial growth factor receptor (VEGFR) signaling by BSF476921 attenuates regional cerebral edema following traumatic brain injury in rats. Restorative Neurology and Neuroscience. 22: 73-9. PMID 15272142  0.776
2004 Conte V, Uryu K, Fujimoto S, Yao Y, Rokach J, Longhi L, Trojanowski JQ, Lee VM, McIntosh TK, Praticò D. Vitamin E reduces amyloidosis and improves cognitive function in Tg2576 mice following repetitive concussive brain injury. Journal of Neurochemistry. 90: 758-64. PMID 15255955 DOI: 10.1111/J.1471-4159.2004.02560.X  0.459
2004 Otori T, Friedland JC, Sinson G, McIntosh TK, Raghupathi R, Welsh FA. Traumatic brain injury elevates glycogen and induces tolerance to ischemia in rat brain. Journal of Neurotrauma. 21: 707-18. PMID 15253799 DOI: 10.1089/0897715041269623  0.703
2004 Siman R, McIntosh TK, Soltesz KM, Chen Z, Neumar RW, Roberts VL. Proteins released from degenerating neurons are surrogate markers for acute brain damage. Neurobiology of Disease. 16: 311-20. PMID 15193288 DOI: 10.1016/J.Nbd.2004.03.016  0.426
2004 Davis JE, Eberwine JH, Hinkle DA, Marciano PG, Meaney DF, McIntosh TK. Methodological considerations regarding single-cell gene expression profiling for brain injury. Neurochemical Research. 29: 1113-21. PMID 15176468 DOI: 10.1023/B:NERE.0000023598.04937.83  0.343
2004 Hoover RC, Motta M, Davis J, Saatman KE, Fujimoto ST, Thompson HJ, Stover JF, Dichter MA, Twyman R, White HS, McIntosh TK. Differential effects of the anticonvulsant topiramate on neurobehavioral and histological outcomes following traumatic brain injury in rats. Journal of Neurotrauma. 21: 501-12. PMID 15165359 DOI: 10.1089/089771504774129847  0.761
2004 Wilson S, Raghupathi R, Saatman KE, MacKinnon MA, McIntosh TK, Graham DI. Continued in situ DNA fragmentation of microglia/macrophages in white matter weeks and months after traumatic brain injury. Journal of Neurotrauma. 21: 239-50. PMID 15115599 DOI: 10.1089/089771504322972031  0.729
2004 Marciano PG, Brettschneider J, Manduchi E, Davis JE, Eastman S, Raghupathi R, Saatman KE, Speed TP, Stoeckert CJ, Eberwine JH, McIntosh TK. Neuron-specific mRNA complexity responses during hippocampal apoptosis after traumatic brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2866-76. PMID 15044525 DOI: 10.1523/Jneurosci.5051-03.2004  0.761
2004 Conte V, Uryu K, Fujimoto S, Yao Y, Rokach J, Longhi L, Trojanowski JQ, Lee VM, McIntosh TK, Pratico D. Vitamin E reduces amyloidosis and improves cognitive function in Tg2576 mice following repetitive concussive brain injury Journal of Neurochemistry. 90: 1541-1541. DOI: 10.1111/J.1471-4159.2004.02807.X  0.426
2004 Maegele M, Sauerland S, Bouillon B, Hess S, McIntosh T, Brockmann M, Mautes A, Neugebauer E. Il-6 Response After Traumatic Brain Injury (Tbi) Is Amplified By A Peripheral Tibia Fracture: A Randomized Controlled Study In Rats.: 54 Shock. 21: 19. DOI: 10.1097/00024382-200406002-00054  0.427
2003 Emery DL, Royo NC, Fischer I, Saatman KE, McIntosh TK. Plasticity following injury to the adult central nervous system: is recapitulation of a developmental state worth promoting? Journal of Neurotrauma. 20: 1271-92. PMID 14748977 DOI: 10.1089/089771503322686085  0.754
2003 Uryu K, Giasson BI, Longhi L, Martinez D, Murray I, Conte V, Nakamura M, Saatman K, Talbot K, Horiguchi T, McIntosh T, Lee VM, Trojanowski JQ. Age-dependent synuclein pathology following traumatic brain injury in mice. Experimental Neurology. 184: 214-24. PMID 14637093 DOI: 10.1016/S0014-4886(03)00245-0  0.659
2003 Raghupathi R, Muir JK, Fulp CT, Pittman RN, McIntosh TK. Acute activation of mitogen-activated protein kinases following traumatic brain injury in the rat: implications for posttraumatic cell death. Experimental Neurology. 183: 438-48. PMID 14552884 DOI: 10.1016/S0014-4886(03)00166-3  0.668
2003 Wagner OI, Lifshitz J, Janmey PA, Linden M, McIntosh TK, Leterrier JF. Mechanisms of mitochondria-neurofilament interactions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9046-58. PMID 14534238 DOI: 10.1523/Jneurosci.23-27-09046.2003  0.502
2003 Smith DH, Uryu K, Saatman KE, Trojanowski JQ, McIntosh TK. Protein accumulation in traumatic brain injury. Neuromolecular Medicine. 4: 59-72. PMID 14528053 DOI: 10.1385/Nmm:4:1-2:59  0.723
2003 Royo NC, Schouten JW, Fulp CT, Shimizu S, Marklund N, Graham DI, McIntosh TK. From cell death to neuronal regeneration: building a new brain after traumatic brain injury. Journal of Neuropathology and Experimental Neurology. 62: 801-11. PMID 14503636 DOI: 10.1093/Jnen/62.8.801  0.672
2003 Yip S, Aboody KS, Burns M, Imitola J, Boockvar JA, Allport J, Park KI, Teng YD, Lachyankar M, McIntosh T, O'Rourke DM, Khoury S, Weissleder R, Black PM, Weiss W, et al. Neural stem cell biology may be well suited for improving brain tumor therapies. Cancer Journal (Sudbury, Mass.). 9: 189-204. PMID 12952304 DOI: 10.1097/00130404-200305000-00007  0.331
2003 Raghupathi R, Strauss KI, Zhang C, Krajewski S, Reed JC, McIntosh TK. Temporal alterations in cellular Bax:Bcl-2 ratio following traumatic brain injury in the rat. Journal of Neurotrauma. 20: 421-35. PMID 12803975 DOI: 10.1089/089771503765355504  0.682
2003 Thompson HJ, Tkacs NC, Saatman KE, Raghupathi R, McIntosh TK. Hyperthermia following traumatic brain injury: a critical evaluation. Neurobiology of Disease. 12: 163-73. PMID 12742737 DOI: 10.1016/S0969-9961(02)00030-X  0.733
2003 Watson DJ, Longhi L, Lee EB, Fulp CT, Fujimoto S, Royo NC, Passini MA, Trojanowski JQ, Lee VM, McIntosh TK, Wolfe JH. Genetically modified NT2N human neuronal cells mediate long-term gene expression as CNS grafts in vivo and improve functional cognitive outcome following experimental traumatic brain injury. Journal of Neuropathology and Experimental Neurology. 62: 368-80. PMID 12722829 DOI: 10.1093/Jnen/62.4.368  0.372
2003 Lifshitz J, McIntosh TK. Age-associated mitochondrial DNA deletions are not evident chronically after experimental brain injury in the rat. Journal of Neurotrauma. 20: 139-49. PMID 12675968 DOI: 10.1089/08977150360547062  0.552
2003 Lifshitz J, Friberg H, Neumar RW, Raghupathi R, Welsh FA, Janmey P, Saatman KE, Wieloch T, Grady MS, McIntosh TK. Structural and functional damage sustained by mitochondria after traumatic brain injury in the rat: evidence for differentially sensitive populations in the cortex and hippocampus. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 219-31. PMID 12571453 DOI: 10.1097/01.Wcb.0000040581.43808.03  0.817
2003 Conte V, Royo NC, Shimizu S, Saatman KE, Watson DJ, Graham DI, Stocchetti N, McIntosh TK. Neurotrophic Factors: Pathophysiology and Therapeutic Applications in Traumatic Brain Injury European Journal of Trauma. 29: 335-355. DOI: 10.1007/S00068-003-1335-Z  0.702
2002 Iwata A, Chen XH, McIntosh TK, Browne KD, Smith DH. Long-term accumulation of amyloid-beta in axons following brain trauma without persistent upregulation of amyloid precursor protein genes. Journal of Neuropathology and Experimental Neurology. 61: 1056-68. PMID 12484568 DOI: 10.1093/Jnen/61.12.1056  0.598
2002 Marciano PG, Eberwine JH, Ragupathi R, Saatman KE, Meaney DF, McIntosh TK. Expression profiling following traumatic brain injury: a review. Neurochemical Research. 27: 1147-55. PMID 12462413 DOI: 10.1023/A:1020973308941  0.687
2002 Leclercq PD, Stephenson MS, Murray LS, McIntosh TK, Graham DI, Gentleman SM. Simple morphometry of axonal swellings cannot be used in isolation for dating lesions after traumatic brain injury. Journal of Neurotrauma. 19: 1183-92. PMID 12427327 DOI: 10.1089/08977150260337985  0.396
2002 Riess P, Zhang C, Saatman KE, Laurer HL, Longhi LG, Raghupathi R, Lenzlinger PM, Lifshitz J, Boockvar J, Neugebauer E, Snyder EY, McIntosh TK. Transplanted neural stem cells survive, differentiate, and improve neurological motor function after experimental traumatic brain injury. Neurosurgery. 51: 1043-52; discussion . PMID 12234415 DOI: 10.1097/00006123-200210000-00035  0.813
2002 Fowler J, MacKinnon MA, Raghupathi R, Saatman KE, McIntosh TK, Graham DI. Age does not influence DNA fragmentation in the hippocampus after fatal traumatic brain injury in young and aged humans compared with controls. Clinical Neuropathology. 21: 156-62. PMID 12143927  0.666
2002 Praticò D, Reiss P, Tang LX, Sung S, Rokach J, McIntosh TK. Local and systemic increase in lipid peroxidation after moderate experimental traumatic brain injury. Journal of Neurochemistry. 80: 894-8. PMID 11948253 DOI: 10.1046/J.0022-3042.2002.00777.X  0.501
2002 Raghupathi R, Conti AC, Graham DI, Krajewski S, Reed JC, Grady MS, Trojanowski JQ, McIntosh TK. Mild traumatic brain injury induces apoptotic cell death in the cortex that is preceded by decreases in cellular Bcl-2 immunoreactivity. Neuroscience. 110: 605-16. PMID 11934469 DOI: 10.1016/S0306-4522(01)00461-4  0.758
2002 Uryu K, Laurer H, McIntosh T, Praticò D, Martinez D, Leight S, Lee VM, Trojanowski JQ. Repetitive mild brain trauma accelerates Abeta deposition, lipid peroxidation, and cognitive impairment in a transgenic mouse model of Alzheimer amyloidosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 446-54. PMID 11784789  0.301
2002 Uryu K, Laurer H, McIntosh T, Praticò D, Martinez D, Leight S, Lee VM, Trojanowski JQ. Repetitive Mild Brain Trauma Accelerates Aβ Deposition, Lipid Peroxidation, and Cognitive Impairment in a Transgenic Mouse Model of Alzheimer Amyloidosis The Journal of Neuroscience. 22: 446-454. DOI: 10.1523/Jneurosci.22-02-00446.2002  0.418
2001 Marciano P, Eberwine JH, Raghupathi R, McIntosh TK. The assessment of genomic alterations using DNA arrays following traumatic brain injury: a review. Restorative Neurology and Neuroscience. 18: 105-13. PMID 11847433  0.642
2001 Williams S, Raghupathi R, MacKinnon MA, McIntosh TK, Saatman KE, Graham DI. In situ DNA fragmentation occurs in white matter up to 12 months after head injury in man. Acta Neuropathologica. 102: 581-90. PMID 11761718 DOI: 10.1007/S004010100410  0.689
2001 Laurer HL, Bareyre FM, Lee VM, Trojanowski JQ, Longhi L, Hoover R, Saatman KE, Raghupathi R, Hoshino S, Grady MS, McIntosh TK. Mild head injury increasing the brain's vulnerability to a second concussive impact. Journal of Neurosurgery. 95: 859-70. PMID 11702878 DOI: 10.3171/Jns.2001.95.5.0859  0.827
2001 Longhi L, Saatman KE, Raghupathi R, Laurer HL, Lenzlinger PM, Riess P, Neugebauer E, Trojanowski JQ, Lee VM, Grady MS, Graham DI, McIntosh TK. A review and rationale for the use of genetically engineered animals in the study of traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 21: 1241-58. PMID 11702040 DOI: 10.1097/00004647-200111000-00001  0.807
2001 Riess P, Bareyre FM, Saatman KE, Cheney JA, Lifshitz J, Raghupathi R, Grady MS, Neugebauer E, McIntosh TK. Effects of chronic, post-injury Cyclosporin A administration on motor and sensorimotor function following severe, experimental traumatic brain injury. Restorative Neurology and Neuroscience. 18: 1-8. PMID 11673665  0.838
2001 Marklund N, Clausen F, McIntosh TK, Hillered L. Free radical scavenger posttreatment improves functional and morphological outcome after fluid percussion injury in the rat. Journal of Neurotrauma. 18: 821-32. PMID 11526988 DOI: 10.1089/089771501316919184  0.676
2001 Philips MF, Mattiasson G, Wieloch T, Björklund A, Johansson BB, Tomasevic G, Martínez-Serrano A, Lenzlinger PM, Sinson G, Grady MS, McIntosh TK. Neuroprotective and behavioral efficacy of nerve growth factor-transfected hippocampal progenitor cell transplants after experimental traumatic brain injury. Journal of Neurosurgery. 94: 765-74. PMID 11354408 DOI: 10.3171/Jns.2001.94.5.0765  0.641
2001 LaPlaca MC, Zhang J, Raghupathi R, Li JH, Smith F, Bareyre FM, Snyder SH, Graham DI, McIntosh TK. Pharmacologic inhibition of poly(ADP-ribose) polymerase is neuroprotective following traumatic brain injury in rats. Journal of Neurotrauma. 18: 369-76. PMID 11336438 DOI: 10.1089/089771501750170912  0.787
2001 Cheney JA, Weisser JD, Bareyre FM, Laurer HL, Saatman KE, Raghupathi R, Gribkoff V, Starrett JE, McIntosh TK. The maxi-K channel opener BMS-204352 attenuates regional cerebral edema and neurologic motor impairment after experimental brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 21: 396-403. PMID 11323525 DOI: 10.1097/00004647-200104000-00008  0.742
2001 Bentzer P, Mattiasson G, McIntosh TK, Wieloch T, Grande PO. Infusion of prostacyclin following experimental brain injury in the rat reduces cortical lesion volume. Journal of Neurotrauma. 18: 275-85. PMID 11284548 DOI: 10.1089/08977150151070919  0.498
2001 Bareyre FM, Raghupathi R, Saatman KE, McIntosh TK. DNase I disinhibition is predominantly associated with actin hyperpolymerization after traumatic brain injury. Journal of Neurochemistry. 77: 173-81. PMID 11279273 DOI: 10.1046/J.1471-4159.2001.00215.X  0.757
2001 Saatman KE, Bareyre FM, Grady MS, McIntosh TK. Acute cytoskeletal alterations and cell death induced by experimental brain injury are attenuated by magnesium treatment and exacerbated by magnesium deficiency. Journal of Neuropathology and Experimental Neurology. 60: 183-94. PMID 11273006 DOI: 10.1093/Jnen/60.2.183  0.779
2001 Sinson G, Bagley LJ, Cecil KM, Torchia M, McGowan JC, Lenkinski RE, McIntosh TK, Grossman RI. Magnetization transfer imaging and proton MR spectroscopy in the evaluation of axonal injury: correlation with clinical outcome after traumatic brain injury. Ajnr. American Journal of Neuroradiology. 22: 143-51. PMID 11158900  0.346
2000 O'Dell DM, Muir JK, Zhang C, Bareyre FM, Saatman KE, Raghupathi R, Welsh F, McIntosh TK. Lubeluzole treatment does not attenuate neurobehavioral dysfunction or CA3 hippocampal neuronal loss following traumatic brain injury in rats. Restorative Neurology and Neuroscience. 16: 127-134. PMID 12671215  0.769
2000 Bareyre FM, Saatman KE, Raghupathi R, McIntosh TK. Postinjury treatment with magnesium chloride attenuates cortical damage after traumatic brain injury in rats. Journal of Neurotrauma. 17: 1029-39. PMID 11101206 DOI: 10.1089/Neu.2000.17.1029  0.796
2000 Leoni MJ, Chen XH, Mueller AL, Cheney J, McIntosh TK, Smith DH. NPS 1506 attenuates cognitive dysfunction and hippocampal neuron death following brain trauma in the rat. Experimental Neurology. 166: 442-9. PMID 11085909 DOI: 10.1006/Exnr.2000.7513  0.543
2000 Raghupathi R, Graham DI, McIntosh TK. Apoptosis after traumatic brain injury. Journal of Neurotrauma. 17: 927-38. PMID 11063058 DOI: 10.1089/Neu.2000.17.927  0.554
2000 Smith FM, Raghupathi R, MacKinnon MA, McIntosh TK, Saatman KE, Meaney DF, Graham DI. TUNEL-positive staining of surface contusions after fatal head injury in man. Acta Neuropathologica. 100: 537-45. PMID 11045676 DOI: 10.1007/S004010000222  0.77
2000 Blaha GR, Raghupathi R, Saatman KE, McIntosh TK. Brain-derived neurotrophic factor administration after traumatic brain injury in the rat does not protect against behavioral or histological deficits. Neuroscience. 99: 483-93. PMID 11029540 DOI: 10.1016/S0306-4522(00)00214-1  0.843
2000 Galvin JE, Nakamura M, McIntosh TK, Saatman KE, Sampathu D, Raghupathi R, Lee VM, Trojanowski JQ. Neurofilament-rich intraneuronal inclusions exacerbate neurodegenerative sequelae of brain trauma in NFH/LacZ transgenic mice. Experimental Neurology. 165: 77-89. PMID 10964487 DOI: 10.1006/Exnr.2000.7461  0.749
2000 Morrison B, Meaney DF, Margulies SS, McIntosh TK. Dynamic mechanical stretch of organotypic brain slice cultures induces differential genomic expression: relationship to mechanical parameters. Journal of Biomechanical Engineering. 122: 224-30. PMID 10923289 DOI: 10.1115/1.429650  0.32
2000 Emery DL, Raghupathi R, Saatman KE, Fischer I, Grady MS, McIntosh TK. Bilateral growth-related protein expression suggests a transient increase in regenerative potential following brain trauma. The Journal of Comparative Neurology. 424: 521-31. PMID 10906717 DOI: 10.1002/1096-9861(20000828)424:3<521::Aid-Cne9>3.0.Co;2-8  0.823
2000 O'Dell DM, Raghupathi R, Crino PB, Eberwine JH, McIntosh TK. Traumatic brain injury alters the molecular fingerprint of TUNEL-positive cortical neurons In vivo: A single-cell analysis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 4821-8. PMID 10864939 DOI: 10.1523/Jneurosci.20-13-04821.2000  0.679
2000 Nakagawa Y, Reed L, Nakamura M, McIntosh TK, Smith DH, Saatman KE, Raghupathi R, Clemens J, Saido TC, Lee VM, Trojanowski JQ. Brain trauma in aged transgenic mice induces regression of established abeta deposits. Experimental Neurology. 163: 244-52. PMID 10785464 DOI: 10.1006/Exnr.2000.7375  0.772
2000 Mattiasson GJ, Philips MF, Tomasevic G, Johansson BB, Wieloch T, McIntosh TK. The rotating pole test: evaluation of its effectiveness in assessing functional motor deficits following experimental head injury in the rat. Journal of Neuroscience Methods. 95: 75-82. PMID 10776817 DOI: 10.1016/S0165-0270(99)00162-4  0.465
2000 Morrison B, Eberwine JH, Meaney DF, McIntosh TK. Traumatic injury induces differential expression of cell death genes in organotypic brain slice cultures determined by complementary DNA array hybridization. Neuroscience. 96: 131-9. PMID 10683418 DOI: 10.1016/S0306-4522(99)00537-0  0.432
2000 Bagley LJ, McGowan JC, Grossman RI, Sinson G, Kotapka M, Lexa FJ, Berlin JA, McIntosh TK. Magnetization transfer imaging of traumatic brain injury. Journal of Magnetic Resonance Imaging : Jmri. 11: 1-8. PMID 10676614 DOI: 10.1002/(Sici)1522-2586(200001)11:1<1::Aid-Jmri1>3.0.Co;2-H  0.378
2000 Graham DI, Raghupathi R, Saatman KE, Meaney D, McIntosh TK. Tissue tears in the white matter after lateral fluid percussion brain injury in the rat: relevance to human brain injury. Acta Neuropathologica. 99: 117-24. PMID 10672317 DOI: 10.1007/Pl00007414  0.782
2000 Saatman KE, Zhang C, Bartus RT, McIntosh TK. Behavioral efficacy of posttraumatic calpain inhibition is not accompanied by reduced spectrin proteolysis, cortical lesion, or apoptosis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 66-73. PMID 10616794 DOI: 10.1097/00004647-200001000-00010  0.576
1999 Nonaka M, Chen XH, Pierce JE, Leoni MJ, McIntosh TK, Wolf JA, Smith DH. Prolonged activation of NF-kappaB following traumatic brain injury in rats. Journal of Neurotrauma. 16: 1023-34. PMID 10595819 DOI: 10.1089/Neu.1999.16.1023  0.54
1999 Sanderson KL, Raghupathi R, Saatman KE, Martin D, Miller G, McIntosh TK. Interleukin-1 receptor antagonist attenuates regional neuronal cell death and cognitive dysfunction after experimental brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 19: 1118-25. PMID 10532636 DOI: 10.1097/00004647-199910000-00008  0.689
1999 Muir JK, Raghupathi R, Emery DL, Bareyre FM, McIntosh TK. Postinjury magnesium treatment attenuates traumatic brain injury-induced cortical induction of p53 mRNA in rats. Experimental Neurology. 159: 584-93. PMID 10506531 DOI: 10.1006/Exnr.1999.7187  0.781
1999 Zhang C, Raghupathi R, Saatman KE, LaPlaca MC, McIntosh TK. Regional and temporal alterations in DNA fragmentation factor (DFF)-like proteins following experimental brain trauma in the rat. Journal of Neurochemistry. 73: 1650-9. PMID 10501212 DOI: 10.1046/J.1471-4159.1999.0731650.X  0.763
1999 Nakamura M, Raghupathi R, Merry DE, Scherbel U, Saatman KE, Mcintosh TK. Overexpression of Bcl-2 is neuroprotective after experimental brain injury in transgenic mice. The Journal of Comparative Neurology. 412: 681-92. PMID 10464363 DOI: 10.1002/(Sici)1096-9861(19991004)412:4<681::Aid-Cne9>3.0.Co;2-F  0.689
1999 Nakagawa Y, Nakamura M, McIntosh TK, Rodriguez A, Berlin JA, Smith DH, Saatman KE, Raghupathi R, Clemens J, Saido TC, Schmidt ML, Lee VM, Trojanowski JQ. Traumatic brain injury in young, amyloid-beta peptide overexpressing transgenic mice induces marked ipsilateral hippocampal atrophy and diminished Abeta deposition during aging. The Journal of Comparative Neurology. 411: 390-8. PMID 10413774 DOI: 10.1002/(Sici)1096-9861(19990830)411:3<390::Aid-Cne3>3.0.Co;2-#  0.765
1999 Philips MF, Muir JK, Saatman KE, Raghupathi R, Lee VM, Trojanowski JQ, McIntosh TK. Survival and integration of transplanted postmitotic human neurons following experimental brain injury in immunocompetent rats. Journal of Neurosurgery. 90: 116-24. PMID 10413164 DOI: 10.3171/Jns.1999.90.1.0116  0.771
1999 Nakamura M, Saatman KE, Galvin JE, Scherbel U, Raghupathi R, Trojanowski JQ, McIntosh TK. Increased vulnerability of NFH-LacZ transgenic mouse to traumatic brain injury-induced behavioral deficits and cortical damage. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 19: 762-70. PMID 10413031 DOI: 10.1097/00004647-199907000-00006  0.778
1999 Scherbel U, Raghupathi R, Nakamura M, Saatman KE, Trojanowski JQ, Neugebauer E, Marino MW, McIntosh TK. Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury. Proceedings of the National Academy of Sciences of the United States of America. 96: 8721-6. PMID 10411942 DOI: 10.1073/Pnas.96.15.8721  0.761
1999 Napieralski JA, Raghupathi R, McIntosh TK. The tumor-suppressor gene, p53, is induced in injured brain regions following experimental traumatic brain injury. Brain Research. Molecular Brain Research. 71: 78-86. PMID 10407189 DOI: 10.1016/S0169-328X(99)00155-2  0.697
1999 Hill-Felberg SJ, McIntosh TK, Oliver DL, Raghupathi R, Barbarese E. Concurrent loss and proliferation of astrocytes following lateral fluid percussion brain injury in the adult rat. Journal of Neuroscience Research. 57: 271-9. PMID 10398305 DOI: 10.1002/(Sici)1097-4547(19990715)57:2<271::Aid-Jnr13>3.0.Co;2-Z  0.704
1999 Bareyre FM, Saatman KE, Helfaer MA, Sinson G, Weisser JD, Brown AL, McIntosh TK. Alterations in ionized and total blood magnesium after experimental traumatic brain injury: relationship to neurobehavioral outcome and neuroprotective efficacy of magnesium chloride. Journal of Neurochemistry. 73: 271-80. PMID 10386980 DOI: 10.1046/J.1471-4159.1999.0730271.X  0.656
1999 LaPlaca MC, Raghupathi R, Verma A, Pieper AA, Saatman KE, Snyder SH, McIntosh TK. Temporal patterns of poly(ADP-ribose) polymerase activation in the cortex following experimental brain injury in the rat. Journal of Neurochemistry. 73: 205-13. PMID 10386972 DOI: 10.1046/J.1471-4159.1999.0730205.X  0.805
1999 Chen XH, Meaney DF, Xu BN, Nonaka M, McIntosh TK, Wolf JA, Saatman KE, Smith DH. Evolution of neurofilament subtype accumulation in axons following diffuse brain injury in the pig. Journal of Neuropathology and Experimental Neurology. 58: 588-96. PMID 10374749 DOI: 10.1097/00005072-199906000-00003  0.685
1999 Muir JK, Raghupathi R, Saatman KE, Wilson CA, Lee VM, Trojanowski JQ, Philips MF, McIntosh TK. Terminally differentiated human neurons survive and integrate following transplantation into the traumatically injured rat brain. Journal of Neurotrauma. 16: 403-14. PMID 10369560 DOI: 10.1089/Neu.1999.16.403  0.776
1999 McGowan JC, McCormack TM, Grossman RI, Mendonça R, Chen XH, Berlin JA, Meaney DF, Xu BN, Cecil KM, McIntosh TK, Smith DH. Diffuse axonal pathology detected with magnetization transfer imaging following brain injury in the pig. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 41: 727-33. PMID 10332848 DOI: 10.1002/(Sici)1522-2594(199904)41:4<727::Aid-Mrm11>3.0.Co;2-6  0.533
1999 Guluma KZ, Saatman KE, Brown A, Raghupathi R, McIntosh TK. Sequential pharmacotherapy with magnesium chloride and basic fibroblast growth factor after fluid percussion brain injury results in less neuromotor efficacy than that achieved with magnesium alone. Journal of Neurotrauma. 16: 311-21. PMID 10225217 DOI: 10.1089/Neu.1999.16.311  0.689
1999 Steward O, Schauwecker PE, Guth L, Zhang Z, Fujiki M, Inman D, Wrathall J, Kempermann G, Gage FH, Saatman KE, Raghupathi R, McIntosh T. Genetic approaches to neurotrauma research: opportunities and potential pitfalls of murine models. Experimental Neurology. 157: 19-42. PMID 10222106 DOI: 10.1006/Exnr.1999.7040  0.718
1999 Shreiber DI, Bain AC, Ross DT, Smith DH, Gennarelli TA, McIntosh TK, Meaney DF. Experimental investigation of cerebral contusion: histopathological and immunohistochemical evaluation of dynamic cortical deformation. Journal of Neuropathology and Experimental Neurology. 58: 153-64. PMID 10029098 DOI: 10.1097/00005072-199902000-00005  0.614
1999 Weisser JD, Laurer H, Raghupathi R, McIntosh TK. APOPTOTIC CELL DEATH IS INCREASED IN THE BRAINSTEM AFTER HEMORRHAGIC SHOCK IN RATS Shock. 11: 78. DOI: 10.1097/00024382-199906001-00269  0.554
1999 Kesavulu V, Keller J, Helfaer MA, McIntosh TK, Welsh F, Raghupathi R. Hypoxic hypoxemia increases mortality and morbidity with mild experimental traumatic brain injury Critical Care Medicine. 27: A63. DOI: 10.1097/00003246-199912001-00146  0.669
1999 Huh J, Saatman KE, Raghupathi R, Laurer HL, Helfaer MA, McIntosh TK. Dephosphorylated neurofilaments are vulnerable following focal traumatic brain injury in mice Critical Care Medicine. 27: A59. DOI: 10.1097/00003246-199912001-00138  0.689
1999 Priestley M, Helfaer M, Bareyre F, McIntosh T. Decreased ionized magnesium measurements in traumatic brain injured pediatric patients Critical Care Medicine. 27: A182. DOI: 10.1097/00003246-199901001-00546  0.403
1999 Ragnarsson KT, Clarke WR, Daling JR, Garber SL, Gustafson CF, Holland AL, Jordan BD, Parker JC, Riddle MA, Roth EJ, Seltzer MM, Simpson KN, Therrien B, Wexler BE, Yawn BP, ... ... McIntosh TK, et al. Rehabilitation of persons with traumatic brain injury Journal of the American Medical Association. 282: 974-983. DOI: 10.1001/Jama.282.10.974  0.633
1998 Saatman KE, Graham DI, McIntosh TK. The neuronal cytoskeleton is at risk after mild and moderate brain injury. Journal of Neurotrauma. 15: 1047-58. PMID 9872461 DOI: 10.1089/Neu.1998.15.1047  0.576
1998 Morrison B, Saatman KE, Meaney DF, McIntosh TK. In vitro central nervous system models of mechanically induced trauma: a review. Journal of Neurotrauma. 15: 911-28. PMID 9840765 DOI: 10.1089/Neu.1998.15.911  0.69
1998 Raghupathi R, McIntosh TK. Pharmacotherapy for traumatic brain injury: a review. Proceedings of the Western Pharmacology Society. 41: 241-6. PMID 9836300  0.505
1998 McIntosh TK, Juhler M, Wieloch T. Novel pharmacologic strategies in the treatment of experimental traumatic brain injury: 1998. Journal of Neurotrauma. 15: 731-69. PMID 9814632 DOI: 10.1089/Neu.1998.15.731  0.489
1998 Raghupathi R, Fernandez SC, Murai H, Trusko SP, Scott RW, Nishioka WK, McIntosh TK. BCL-2 overexpression attenuates cortical cell loss after traumatic brain injury in transgenic mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 18: 1259-69. PMID 9809516 DOI: 10.1097/00004647-199811000-00013  0.554
1998 O'Dell DM, Raghupathi R, Crino PB, Morrison B, Eberwine JH, McIntosh TK. Amplification of mRNAs from single, fixed, TUNEL-positive cells. Biotechniques. 25: 566-8, 570. PMID 9793634 DOI: 10.2144/98254Bm04  0.532
1998 McIntosh TK, Saatman KE, Raghupathi R, Graham DI, Smith DH, Lee VM, Trojanowski JQ. The Dorothy Russell Memorial Lecture. The molecular and cellular sequelae of experimental traumatic brain injury: pathogenetic mechanisms. Neuropathology and Applied Neurobiology. 24: 251-67. PMID 9775390 DOI: 10.1046/J.1365-2990.1998.00121.X  0.786
1998 Smith DH, Cecil KM, Meaney DF, Chen XH, McIntosh TK, Gennarelli TA, Lenkinski RE. Magnetic resonance spectroscopy of diffuse brain trauma in the pig. Journal of Neurotrauma. 15: 665-74. PMID 9753214 DOI: 10.1089/Neu.1998.15.665  0.557
1998 Pierce JE, Smith DH, Trojanowski JQ, McIntosh TK. Enduring cognitive, neurobehavioral and histopathological changes persist for up to one year following severe experimental brain injury in rats. Neuroscience. 87: 359-69. PMID 9740398 DOI: 10.1016/S0306-4522(98)00142-0  0.643
1998 Smith DH, Nakamura M, McIntosh TK, Wang J, Rodríguez A, Chen XH, Raghupathi R, Saatman KE, Clemens J, Schmidt ML, Lee VM, Trojanowski JQ. Brain trauma induces massive hippocampal neuron death linked to a surge in beta-amyloid levels in mice overexpressing mutant amyloid precursor protein. The American Journal of Pathology. 153: 1005-10. PMID 9736050 DOI: 10.1016/S0002-9440(10)65643-X  0.774
1998 Raghupathi R, Grants I, Rosenberg LJ, McIntosh TK, Lucas JH. Increased jun immunoreactivity in an in vitro model of mammalian spinal neuron physical injury. Journal of Neurotrauma. 15: 555-61. PMID 9674558 DOI: 10.1089/Neu.1998.15.555  0.614
1998 Conti AC, Raghupathi R, Trojanowski JQ, McIntosh TK. Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 5663-72. PMID 9671657 DOI: 10.1523/Jneurosci.18-15-05663.1998  0.688
1998 Okiyama K, Smith DH, White WF, McIntosh TK. Effects of the NMDA antagonist CP-98,113 on regional cerebral edema and cardiovascular, cognitive, and neurobehavioral function following experimental brain injury in the rat. Brain Research. 792: 291-8. PMID 9593949 DOI: 10.1016/S0006-8993(98)00158-9  0.45
1998 Zhang C, Raghupathi R, Saatman KE, Smith DH, Stutzmann JM, Wahl F, McIntosh TK. Riluzole attenuates cortical lesion size, but not hippocampal neuronal loss, following traumatic brain injury in the rat. Journal of Neuroscience Research. 52: 342-9. PMID 9590442 DOI: 10.1002/(Sici)1097-4547(19980501)52:3<342::Aid-Jnr10>3.0.Co;2-8  0.725
1998 Cecil KM, Hills EC, Sandel ME, Smith DH, McIntosh TK, Mannon LJ, Sinson GP, Bagley LJ, Grossman RI, Lenkinski RE. Proton magnetic resonance spectroscopy for detection of axonal injury in the splenium of the corpus callosum of brain-injured patients. Journal of Neurosurgery. 88: 795-801. PMID 9576245 DOI: 10.3171/Jns.1998.88.5.0795  0.576
1998 Cecil KM, Lenkinski RE, Meaney DF, McIntosh TK, Smith DH. High-field proton magnetic resonance spectroscopy of a swine model for axonal injury. Journal of Neurochemistry. 70: 2038-44. PMID 9572290 DOI: 10.1046/J.1471-4159.1998.70052038.X  0.586
1998 Morrison B, Meaney DF, McIntosh TK. Mechanical characterization of an in vitro device designed to quantitatively injure living brain tissue. Annals of Biomedical Engineering. 26: 381-90. PMID 9570221 DOI: 10.1114/1.61  0.387
1998 Murai H, Pierce JE, Raghupathi R, Smith DH, Saatman KE, Trojanowski JQ, Lee VM, Loring JF, Eckman C, Younkin S, McIntosh TK. Twofold overexpression of human beta-amyloid precursor proteins in transgenic mice does not affect the neuromotor, cognitive, or neurodegenerative sequelae following experimental brain injury. The Journal of Comparative Neurology. 392: 428-38. PMID 9514508 DOI: 10.1002/(Sici)1096-9861(19980323)392:4<428::Aid-Cne2>3.0.Co;2-2  0.785
1998 Philips MF, Wieloch T, Björklund A, Mattiasson G, Johansson BB, Tomasevic G, McIntosh TK. Neuroprotective and Behavioral Efficacy of NGF-transfected Hippocampal Progenitor Cells Transplanted into the Peri-injured Cortex of Rats after Lateral Fluid Percussion Brain Injury Neurosurgery. 43: 699-700. DOI: 10.1097/00006123-199809000-00293  0.452
1998 Galvin JE, -Y. Lee VM, Nakamura M, Saatman KE, Raghupathi R, McIntosh TK, Troianowski JQ. NEURONAL LOSS AND CYTOSKELETAL PERTURBATION AFTER TRAUMATIC BRAIN INJURY (TBI) IN THE NFH/LacZ TRANSGENIC MOUSE Journal of Neuropathology and Experimental Neurology. 57: 475. DOI: 10.1097/00005072-199805000-00039  0.689
1997 Bareyre F, Wahl F, McIntosh TK, Stutzmann JM. Time course of cerebral edema after traumatic brain injury in rats: effects of riluzole and mannitol. Journal of Neurotrauma. 14: 839-49. PMID 9421455 DOI: 10.1089/Neu.1997.14.839  0.451
1997 Smith DH, Chen XH, Pierce JE, Wolf JA, Trojanowski JQ, Graham DI, McIntosh TK. Progressive atrophy and neuron death for one year following brain trauma in the rat. Journal of Neurotrauma. 14: 715-27. PMID 9383090 DOI: 10.1089/Neu.1997.14.715  0.642
1997 Saatman KE, Contreras PC, Smith DH, Raghupathi R, McDermott KL, Fernandez SC, Sanderson KL, Voddi M, McIntosh TK. Insulin-like growth factor-1 (IGF-1) improves both neurological motor and cognitive outcome following experimental brain injury. Experimental Neurology. 147: 418-27. PMID 9344566 DOI: 10.1006/Exnr.1997.6629  0.794
1997 Smith DH, Perri BR, Raghupathi R, Saatman KE, McIntosh TK. Remacemide hydrochloride reduces cortical lesion volume following brain trauma in the rat. Neuroscience Letters. 231: 135-8. PMID 9300640 DOI: 10.1016/S0304-3940(97)00551-X  0.725
1997 Rubin Y, Cecil K, Wehrli S, McIntosh TK, Lenkinski RE, Smith DH. High-resolution 1H NMR spectroscopy following experimental brain trauma. Journal of Neurotrauma. 14: 441-9. PMID 9257662 DOI: 10.1089/Neu.1997.14.441  0.616
1997 McIntosh TK, Garde E, Saatman KE, Smith DH. Central nervous system resuscitation. Emergency Medicine Clinics of North America. 15: 527-50. PMID 9255131 DOI: 10.1016/S0733-8627(05)70316-3  0.643
1997 Smith DH, Chen XH, Xu BN, McIntosh TK, Gennarelli TA, Meaney DF. Characterization of diffuse axonal pathology and selective hippocampal damage following inertial brain trauma in the pig. Journal of Neuropathology and Experimental Neurology. 56: 822-34. PMID 9210879 DOI: 10.1097/00005072-199756070-00009  0.599
1997 Okiyama K, Smith DH, White WF, Richter K, McIntosh TK. Effects of the novel NMDA antagonists CP-98,113, CP-101,581 and CP-101,606 on cognitive function and regional cerebral edema following experimental brain injury in the rat. Journal of Neurotrauma. 14: 211-22. PMID 9151770 DOI: 10.1089/Neu.1997.14.211  0.45
1997 McDermott KL, Raghupathi R, Fernandez SC, Saatman KE, Protter AA, Finklestein SP, Sinson G, Smith DH, McIntosh TK. Delayed administration of basic fibroblast growth factor (bFGF) attenuates cognitive dysfunction following parasagittal fluid percussion brain injury in the rat. Journal of Neurotrauma. 14: 191-200. PMID 9151768 DOI: 10.1089/Neu.1997.14.191  0.725
1997 Perri BR, Smith DH, Murai H, Sinson G, Saatman KE, Raghupathi R, Bartus RT, McIntosh TK. Metabolic quantification of lesion volume following experimental traumatic brain injury in the rat. Journal of Neurotrauma. 14: 15-22. PMID 9048307 DOI: 10.1089/Neu.1997.14.15  0.725
1997 Sinson G, Perri BR, Trojanowski JQ, Flamm ES, McIntosh TK. Improvement of cognitive deficits and decreased cholinergic neuronal cell loss and apoptotic cell death following neurotrophin infusion after experimental traumatic brain injury. Journal of Neurosurgery. 86: 511-8. PMID 9046309 DOI: 10.3171/Jns.1997.86.3.0511  0.38
1997 Vink R, Golding EM, Williams JP, McIntosh TK. Blood glucose concentration does not affect outcome in brain trauma: A 31P MRS study. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 17: 50-3. PMID 8978386 DOI: 10.1097/00004647-199701000-00007  0.456
1997 Mcintosh TK, Saatman KE, Raghupathi R. REVIEW ■ : Calcium and the Pathogenesis of Traumatic CNS Injury: Cellular and Molecular Mechanisms The Neuroscientist. 3: 169-175. DOI: 10.1177/107385849700300310  0.689
1997 Povlishock JT, Marmarou A, McIntosh T, Trojanowski JQ, Moroi J. Impact acceleration injury in the rat: evidence for focal axolemmal change and related neurofilament sidearm alteration. Journal of Neuropathology and Experimental Neurology. 56: 347-359. DOI: 10.1097/00005072-199704000-00003  0.627
1997 Raghupathi R, McIntosh TK. Drugs in the management of acute traumatic brain injury Physical Medicine and Rehabilitation Clinics of North America. 8: 629-649. DOI: 10.1016/S1047-9651(18)30294-8  0.554
1997 Mcintosh TK, Saatman KE, Raghupathi R. Calcium and the pathogenesis of traumatic CNS injury: Cellular and molecular mechanisms Neuroscientist. 3: 169-175.  0.666
1996 McIntosh TK, Smith DH, Voddi M, Perri BR, Stutzmann JM. Riluzole, a novel neuroprotective agent, attenuates both neurologic motor and cognitive dysfunction following experimental brain injury in the rat. Journal of Neurotrauma. 13: 767-80. PMID 9002062 DOI: 10.1089/Neu.1996.13.767  0.45
1996 Fan L, Young PR, Barone FC, Feuerstein GZ, Smith DH, McIntosh TK. Experimental brain injury induces differential expression of tumor necrosis factor-alpha mRNA in the CNS. Brain Research. Molecular Brain Research. 36: 287-91. PMID 8965649 DOI: 10.1016/0169-328X(95)00274-V  0.45
1996 Saatman KE, Bozyczko-Coyne D, Marcy V, Siman R, McIntosh TK. Prolonged calpain-mediated spectrin breakdown occurs regionally following experimental brain injury in the rat. Journal of Neuropathology and Experimental Neurology. 55: 850-60. PMID 8965100 DOI: 10.1097/00005072-199607000-00010  0.576
1996 Hill SJ, Barbarese E, McIntosh TK. Regional heterogeneity in the response of astrocytes following traumatic brain injury in the adult rat. Journal of Neuropathology and Experimental Neurology. 55: 1221-9. PMID 8957445 DOI: 10.1097/00005072-199612000-00005  0.497
1996 Alsop DC, Murai H, Detre JA, McIntosh TK, Smith DH. Detection of acute pathologic changes following experimental traumatic brain injury using diffusion-weighted magnetic resonance imaging. Journal of Neurotrauma. 13: 515-21. PMID 8913968 DOI: 10.1089/Neu.1996.13.515  0.588
1996 Hicks R, Soares H, Smith D, McIntosh T. Temporal and spatial characterization of neuronal injury following lateral fluid-percussion brain injury in the rat Acta Neuropathologica. 91: 236-246. PMID 8834535 DOI: 10.1007/S004010050421  0.757
1996 McIntosh TK, Smith DH, Meaney DF, Kotapka MJ, Gennarelli TA, Graham DI. Neuropathological sequelae of traumatic brain injury: relationship to neurochemical and biomechanical mechanisms. Laboratory Investigation; a Journal of Technical Methods and Pathology. 74: 315-42. PMID 8780153  0.395
1996 Raghupathi R, McIntosh TK. Regionally and temporally distinct patterns of induction of c-fos, c-jun and junB mRNAs following experimental brain injury in the rat. Brain Research. Molecular Brain Research. 37: 134-44. PMID 8738144 DOI: 10.1016/0169-328X(95)00289-5  0.554
1996 McIntosh TK, Smith DH, Garde E. Therapeutic approaches for the prevention of secondary brain injury. European Journal of Anaesthesiology. 13: 291-309. PMID 8737120 DOI: 10.1046/J.1365-2346.1996.00981.X  0.45
1996 Kimura H, Meaney DF, McGowan JC, Grossman RI, Lenkinski RE, Ross DT, McIntosh TK, Gennarelli TA, Smith DH. Magnetization transfer imaging of diffuse axonal injury following experimental brain injury in the pig: characterization by magnetization transfer ratio with histopathologic correlation. Journal of Computer Assisted Tomography. 20: 540-6. PMID 8708052 DOI: 10.1097/00004728-199607000-00007  0.574
1996 Vink R, Heath DL, McIntosh TK. Acute and prolonged alterations in brain free magnesium following fluid percussion-induced brain trauma in rats. Journal of Neurochemistry. 66: 2477-83. PMID 8632172 DOI: 10.1046/J.1471-4159.1996.66062477.X  0.45
1996 Saatman KE, Murai H, Bartus RT, Smith DH, Hayward NJ, Perri BR, McIntosh TK. Calpain inhibitor AK295 attenuates motor and cognitive deficits following experimental brain injury in the rat. Proceedings of the National Academy of Sciences of the United States of America. 93: 3428-33. PMID 8622952 DOI: 10.1073/Pnas.93.8.3428  0.643
1996 Pierce JE, Trojanowski JQ, Graham DI, Smith DH, McIntosh TK. Immunohistochemical characterization of alterations in the distribution of amyloid precursor proteins and beta-amyloid peptide after experimental brain injury in the rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 1083-90. PMID 8558237 DOI: 10.1523/Jneurosci.16-03-01083.1996  0.616
1995 Raghupathi R, McIntosh TK, Smith DH. Cellular responses to experimental brain injury. Brain Pathology (Zurich, Switzerland). 5: 437-42. PMID 8974626 DOI: 10.1111/J.1750-3639.1995.Tb00622.X  0.595
1995 McIntosh TK, Raghupathi R. Cell stress genes and acute CNS injury. Neuropathology and Applied Neurobiology. 21: 477-9. PMID 8745233  0.505
1995 Soares HD, Sinson GP, McIntosh TK. Fetal hippocampal transplants attenuate CA3 pyramidal cell death resulting from fluid percussion brain injury in the rat. Journal of Neurotrauma. 12: 1059-67. PMID 8742134 DOI: 10.1089/Neu.1995.12.1059  0.609
1995 Smith DH, Meaney DF, Lenkinski RE, Alsop DC, Grossman R, Kimura H, McIntosh TK, Gennarelli TA. New magnetic resonance imaging techniques for the evaluation of traumatic brain injury. Journal of Neurotrauma. 12: 573-7. PMID 8683608 DOI: 10.1089/Neu.1995.12.573  0.575
1995 Soares HD, Hicks RR, Smith D, McIntosh TK. Inflammatory leukocytic recruitment and diffuse neuronal degeneration are separate pathological processes resulting from traumatic brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 8223-33. PMID 8613756  0.713
1995 Hayes RL, Yang K, Raghupathi R, McIntosh TK. Changes in gene expression following traumatic brain injury in the rat. Journal of Neurotrauma. 12: 779-90. PMID 8594207 DOI: 10.1089/Neu.1995.12.779  0.677
1995 Okiyama K, Smith DH, Gennarelli TA, Simon RP, Leach M, McIntosh TK. The sodium channel blocker and glutamate release inhibitor BW1003C87 and magnesium attenuate regional cerebral edema following experimental brain injury in the rat. Journal of Neurochemistry. 64: 802-9. PMID 7830074 DOI: 10.1046/J.1471-4159.1995.64020802.X  0.45
1995 Yamakami I, Vink R, Faden AI, Gennarelli TA, Lenkinski R, McIntosh TK. Effects of acute ethanol intoxication on experimental brain injury in the rat: neurobehavioral and phosphorus-31 nuclear magnetic resonance spectroscopy studies. Journal of Neurosurgery. 82: 813-21. PMID 7714607 DOI: 10.3171/Jns.1995.82.5.0813  0.482
1995 Raghupathi R, Welsh FA, Lowenstein DH, Gennarelli TA, McIntosh TK. Regional induction of c-fos and heat shock protein-72 mRNA following fluid-percussion brain injury in the rat. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 15: 467-73. PMID 7714005 DOI: 10.1038/Jcbfm.1995.58  0.662
1995 Smith DH, Soares HD, Pierce JS, Perlman KG, Saatman KE, Meaney DF, Dixon CE, McIntosh TK. A model of parasagittal controlled cortical impact in the mouse: cognitive and histopathologic effects. Journal of Neurotrauma. 12: 169-78. PMID 7629863 DOI: 10.1089/Neu.1995.12.169  0.831
1995 Hicks RR, Smith DH, McIntosh TK. Temporal response and effects of excitatory amino acid antagonism on microtubule-associated protein 2 immunoreactivity following experimental brain injury in rats. Brain Research. 678: 151-60. PMID 7620884 DOI: 10.1016/0006-8993(95)00179-T  0.666
1995 Fan L, Young PR, Barone FC, Feuerstein GZ, Smith DH, McIntosh TK. Experimental brain injury induces expression of interleukin-1 beta mRNA in the rat brain. Brain Research. Molecular Brain Research. 30: 125-30. PMID 7609633 DOI: 10.1016/0169-328X(94)00287-O  0.45
1995 Smith DH, Casey K, McIntosh TK. Pharmacologic therapy for traumatic brain injury: experimental approaches. New Horizons (Baltimore, Md.). 3: 562-72. PMID 7496768  0.348
1995 Rink A, Fung KM, Trojanowski JQ, Lee VM, Neugebauer E, McIntosh TK. Evidence of apoptotic cell death after experimental traumatic brain injury in the rat. The American Journal of Pathology. 147: 1575-83. PMID 7495282  0.336
1995 Smith DH, Gennarelli TA, McIntosh TK. The Potential of 21-Aminosteroids (Lazaroids) as Neuroprotective Therapies in CNS Injury Cns Drugs. 3: 159-164. DOI: 10.2165/00023210-199503030-00001  0.45
1994 Okiyama K, Rosenkrantz TS, Smith DH, Gennarelli TA, McIntosh TK. (S)-emopamil attenuates acute reduction in regional cerebral blood flow following experimental brain injury. Journal of Neurotrauma. 11: 83-95. PMID 8201628 DOI: 10.1089/Neu.1994.11.83  0.45
1994 Prasad MR, Ramaiah C, McIntosh TK, Dempsey RJ, Hipkens S, Yurek D. Regional levels of lactate and norepinephrine after experimental brain injury. Journal of Neurochemistry. 63: 1086-94. PMID 8051549 DOI: 10.1046/J.1471-4159.1994.63031086.X  0.511
1994 Smith DH, Lowenstein DH, Gennarelli TA, McIntosh TK. Persistent memory dysfunction is associated with bilateral hippocampal damage following experimental brain injury. Neuroscience Letters. 168: 151-4. PMID 8028769 DOI: 10.1016/0304-3940(94)90438-3  0.581
1994 Lowenstein DH, Gwinn RP, Seren MS, Simon RP, McIntosh TK. Increased expression of mRNA encoding calbindin-D28K, the glucose-regulated proteins, or the 72 kDa heat-shock protein in three models of acute CNS injury. Brain Research. Molecular Brain Research. 22: 299-308. PMID 8015387 DOI: 10.1016/0169-328X(94)90058-2  0.445
1994 Hicks RR, Smith DH, Gennarelli TA, McIntosh T. Kynurenate is neuroprotective following experimental brain injury in the rat. Brain Research. 655: 91-6. PMID 7812795 DOI: 10.1016/0006-8993(94)91601-2  0.666
1994 Povlishock JT, Hayes RL, Michel ME, McIntosh TK. Workshop on animal models of traumatic brain injury. Journal of Neurotrauma. 11: 723-32. PMID 7723071 DOI: 10.1089/Neu.1994.11.723  0.681
1993 Tzigaret C, McIntosh TK, Okiyama K, Jenkins WL, Prasad MR. Measurement of hippocampal levels of cellular second messengers following in situ freezing. Journal of Neurochemistry. 60: 827-34. PMID 8436972 DOI: 10.1111/J.1471-4159.1993.Tb03226.X  0.353
1993 Smith DH, Okiyama K, Thomas MJ, McIntosh TK. Effects of the excitatory amino acid receptor antagonists kynurenate and indole-2-carboxylic acid on behavioral and neurochemical outcome following experimental brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 5383-92. PMID 8254381 DOI: 10.1523/Jneurosci.13-12-05383.1993  0.575
1993 Pierce JE, Smith DH, Eison MS, McIntosh TK. The nootropic compound BMY-21502 improves spatial learning ability in brain injured rats. Brain Research. 624: 199-208. PMID 8252392 DOI: 10.1016/0006-8993(93)90078-2  0.45
1993 Smith DH, Okiyama K, Gennarelli TA, McIntosh TK. Magnesium and ketamine attenuate cognitive dysfunction following experimental brain injury. Neuroscience Letters. 157: 211-4. PMID 8233056 DOI: 10.1016/0304-3940(93)90739-8  0.45
1993 Hicks RR, Smith DH, Lowenstein DH, Saint Marie R, McIntosh TK. Mild experimental brain injury in the rat induces cognitive deficits associated with regional neuronal loss in the hippocampus. Journal of Neurotrauma. 10: 405-14. PMID 8145264 DOI: 10.1089/Neu.1993.10.405  0.766
1993 McIntosh TK, Fernyak S, Hayes RL, Faden AI. Beneficial effect of the nonselective opiate antagonist naloxone hydrochloride and the thyrotropin-releasing hormone (TRH) analog YM-14673 on long-term neurobehavioral outcome following experimental brain injury in the rat. Journal of Neurotrauma. 10: 373-84. PMID 8145261 DOI: 10.1089/Neu.1993.10.373  0.478
1992 McIntosh TK, Thomas M, Smith D, Banbury M. The novel 21-aminosteroid U74006F attenuates cerebral edema and improves survival after brain injury in the rat. Journal of Neurotrauma. 9: 33-46. PMID 1619674 DOI: 10.1089/Neu.1992.9.33  0.632
1992 McIntosh TK, Ferriero D. Changes in neuropeptide Y after experimental traumatic brain injury in the rat. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 12: 697-702. PMID 1618947 DOI: 10.1038/Jcbfm.1992.95  0.511
1992 Soares HD, Thomas M, Cloherty K, McIntosh TK. Development of prolonged focal cerebral edema and regional cation changes following experimental brain injury in the rat. Journal of Neurochemistry. 58: 1845-52. PMID 1560237 DOI: 10.1111/J.1471-4159.1992.Tb10061.X  0.609
1992 Okiyama K, Smith DH, Thomas MJ, McIntosh TK. Evaluation of a novel calcium channel blocker, (S)-emopamil, on regional cerebral edema and neurobehavioral function after experimental brain injury. Journal of Neurosurgery. 77: 607-15. PMID 1527621 DOI: 10.3171/Jns.1992.77.4.0607  0.615
1992 Lowenstein DH, Thomas MJ, Smith DH, McIntosh TK. Selective vulnerability of dentate hilar neurons following traumatic brain injury: a potential mechanistic link between head trauma and disorders of the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 4846-53. PMID 1464770  0.353
1992 Prasad MR, Tzigaret CM, Smith D, Soares H, McIntosh TK. Decreased alpha 1-adrenergic receptors after experimental brain injury. Journal of Neurotrauma. 9: 269-79. PMID 1335519 DOI: 10.1089/Neu.1992.9.269  0.666
1991 Smith DH, Okiyama K, Thomas MJ, Claussen B, McIntosh TK. Evaluation of memory dysfunction following experimental brain injury using the Morris water maze. Journal of Neurotrauma. 8: 259-69. PMID 1803034 DOI: 10.1089/Neu.1991.8.259  0.372
1991 Soares H, McIntosh TK. Fetal cortical transplants in adult rats subjected to experimental brain injury. Journal of Neural Transplantation & Plasticity. 2: 207-20. PMID 1782253 DOI: 10.1155/Np.1991.207  0.609
1990 Vink R, Head VA, Rogers PJ, McIntosh TK, Faden AI. Mitochondrial metabolism following traumatic brain injury in rats. Journal of Neurotrauma. 7: 21-7. PMID 2342116 DOI: 10.1089/Neu.1990.7.21  0.455
1990 Hayes RL, Lyeth BG, Jenkins LW, Zimmerman R, McIntosh TK, Clifton GL, Young HF. Possible protective effect of endogenous opioids in traumatic brain injury. Journal of Neurosurgery. 72: 252-61. PMID 2295922 DOI: 10.3171/Jns.1990.72.2.0252  0.357
1990 McIntosh TK, Vink R, Soares H, Hayes R, Simon R. Effect of noncompetitive blockade of N-methyl-D-aspartate receptors on the neurochemical sequelae of experimental brain injury. Journal of Neurochemistry. 55: 1170-9. PMID 2168932 DOI: 10.1111/J.1471-4159.1990.Tb03122.X  0.736
1990 McIntosh TK, Banbury M, Smith D, Thomas M. The novel 21-aminosteroid U-74006F attenuates cerebral oedema and improves survival after brain injury in the rat. Acta Neurochirurgica. Supplementum. 51: 329-30. PMID 2089929  0.429
1990 McIntosh TK, Soares H, Thomas M, Cloherty K. Development of regional cerebral oedema after lateral fluid-percussion brain injury in the rat. Acta Neurochirurgica. Supplementum. 51: 263-4. PMID 2089913 DOI: 10.1007/978-3-7091-9115-6_89  0.609
1989 McIntosh TK, Vink R, Yamakami I, Faden AI. Magnesium protects against neurological deficit after brain injury. Brain Research. 482: 252-60. PMID 2784989 DOI: 10.1016/0006-8993(89)91188-8  0.494
1989 McIntosh TK, Vink R, Noble L, Yamakami I, Fernyak S, Soares H, Faden AL. Traumatic brain injury in the rat: characterization of a lateral fluid-percussion model. Neuroscience. 28: 233-44. PMID 2761692 DOI: 10.1016/0306-4522(89)90247-9  0.733
1989 Demediuk P, Faden AI, Romhanyi R, Vink R, McIntosh TK. Changes in lipid metabolism, tissue cations, and water content after fluid-percussion-induced traumatic brain injury in rats. Journal of Neurotrauma. 6: 229. PMID 2695651 DOI: 10.1089/neu.1989.6.229  0.312
1989 Mcintosh TK, Vink R, Soares H, Hayes R, Simon R. Effects of the N-methyl-D-aspartate receptor blocker MK-801 on neurologic function after experimental brain injury. Journal of Neurotrauma. 6: 247-59. PMID 2559212 DOI: 10.1089/Neu.1989.6.247  0.728
1988 Vink R, McIntosh TK, Yamakami I, Faden AI. 31P NMR characterization of graded traumatic brain injury in rats. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 6: 37-48. PMID 3352504 DOI: 10.1002/Mrm.1910060105  0.38
1988 Vink R, Faden AI, McIntosh TK. Changes in cellular bioenergetic state following graded traumatic brain injury in rats: determination by phosphorus 31 magnetic resonance spectroscopy. Journal of Neurotrauma. 5: 315-30. PMID 3249310 DOI: 10.1089/Neu.1988.5.315  0.357
1988 McIntosh TK, Faden AI, Yamakami I, Vink R. Magnesium deficiency exacerbates and pretreatment improves outcome following traumatic brain injury in rats: 31P magnetic resonance spectroscopy and behavioral studies. Journal of Neurotrauma. 5: 17-31. PMID 3193462 DOI: 10.1089/Neu.1988.5.17  0.402
1988 Vink R, McIntosh TK, Faden AI. Treatment with the thyrotropin-releasing hormone analog CG3703 restores magnesium homeostasis following traumatic brain injury in rats. Brain Research. 460: 184-8. PMID 3146405 DOI: 10.1016/0006-8993(88)91221-8  0.304
1988 McIntosh TK, Vink R, Faden AI. An analogue of thyrotropin-releasing hormone improves outcome after brain injury: 31P-NMR studies. The American Journal of Physiology. 254: R785-92. PMID 3129951 DOI: 10.1152/Ajpregu.1988.254.5.R785  0.471
1988 Demediuk P, Faden AI, Romhanyi R, Vink R, McIntosh TK. Traumatic brain injury in the rat: effects on lipid metabolism, tissue magnesium, and water content. Journal of Neurotrauma. 5: 105-19. PMID 3066912 DOI: 10.1089/Neu.1988.5.105  0.449
1987 McIntosh TK, Noble L, Andrews B, Faden AI. Traumatic brain injury in the rat: characterization of a midline fluid-percussion model. Central Nervous System Trauma : Journal of the American Paralysis Association. 4: 119-34. PMID 3690695 DOI: 10.1089/cns.1987.4.119  0.4
1987 McIntosh TK, Faden AI, Bendall MR, Vink R. Traumatic brain injury in the rat: alterations in brain lactate and pH as characterized by 1H and 31P nuclear magnetic resonance. Journal of Neurochemistry. 49: 1530-40. PMID 3668537 DOI: 10.1111/J.1471-4159.1987.Tb01024.X  0.368
1987 Vink R, McIntosh TK, Weiner MW, Faden AI. Effects of traumatic brain injury on cerebral high-energy phosphates and pH: a 31P magnetic resonance spectroscopy study. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 7: 563-71. PMID 3654796 DOI: 10.1038/Jcbfm.1987.106  0.334
1987 Vink R, McIntosh TK, Demediuk P, Faden AI. Decrease in total and free magnesium concentration following traumatic brain injury in rats. Biochemical and Biophysical Research Communications. 149: 594-9. PMID 3426591 DOI: 10.1016/0006-291X(87)90409-8  0.372
1987 McIntosh TK, Head VA, Faden AI. Alterations in regional concentrations of endogenous opioids following traumatic brain injury in the cat. Brain Research. 425: 225-33. PMID 2892572 DOI: 10.1016/0006-8993(87)90505-1  0.388
1987 McIntosh TK, Hayes RL, DeWitt DS, Agura V, Faden AI. Endogenous opioids may mediate secondary damage after experimental brain injury. The American Journal of Physiology. 253: E565-74. PMID 2891303 DOI: 10.1152/Ajpendo.1987.253.5.E565  0.395
1986 McIntosh TK, Palter M, Grasberger R, Vezina R, Gerstein L, Yeston N, Egdahl RH. Endorphins in primate hemorrhagic shock: beneficial action of opiate antagonists. The Journal of Surgical Research. 40: 265-75. PMID 2936929 DOI: 10.1016/0022-4804(86)90160-5  0.457
1985 McIntosh TK, Palter M, Grasberger R, Vezina R, Yeston NS, Egdahl RH. Effect of an opiate antagonist (naloxone) and an agonist/antagonist (nalbuphine) in primate hemorrhagic shock: relationship to catecholamine release. Circulatory Shock. 17: 313-25. PMID 4092345  0.463
1985 McIntosh TK, Bush HL, Palter M, Hay JR, Aun F, Yeston NS, Egdahl RH. Prolonged disruption of plasma beta-endorphin dynamics following surgery. The Journal of Surgical Research. 38: 210-5. PMID 3157023 DOI: 10.1016/0022-4804(85)90028-9  0.463
1985 McIntosh TK, Bush HL, Yeston NS, Grasberger R, Palter M, Aun F, Egdahl RH. Beta-endorphin, cortisol and postoperative delirium: a preliminary report. Psychoneuroendocrinology. 10: 303-13. PMID 2932761 DOI: 10.1016/0306-4530(85)90007-1  0.463
1984 McIntosh TK, Barfield RJ, Thomas D. Electrophysiological and ultrasonic correlates of reproductive behavior in the male rat. Behavioral Neuroscience. 98: 1100-3. PMID 6508914 DOI: 10.1037//0735-7044.98.6.1100  0.568
1984 Aun F, McIntosh TK, Lee A, Egdahl RH. The effects of surgery on the circadian rhythms of cortisol. International Surgery. 69: 101-5. PMID 6500872  0.463
1984 McIntosh TK, Barfield RJ. Brain monoaminergic control of male reproductive behavior. II. Dopamine and the post-ejaculatory refractory period. Behavioural Brain Research. 12: 267-73. PMID 6432003 DOI: 10.1016/0166-4328(84)90152-9  0.583
1984 McIntosh TK, Barfield RJ. Brain monoaminergic control of male reproductive behavior. I. Serotonin and the post-ejaculatory refractory period. Behavioural Brain Research. 12: 255-65. PMID 6235821 DOI: 10.1016/0166-4328(84)90151-7  0.583
1984 McIntosh TK, Barfield RJ. Brain monoaminergic control of male reproductive behavior. III. Norepinephrine and the post-ejaculatory refractory period. Behavioural Brain Research. 12: 275-81. PMID 6087842 DOI: 10.1016/0166-4328(84)90153-0  0.602
1981 McIntosh TK, Lothrop DA, Lee A, Jackson BT, Nabseth D, Egdahl RH. Circadian rhythm of cortisol is altered in postsurgical patients. The Journal of Clinical Endocrinology and Metabolism. 53: 117-22. PMID 7240369 DOI: 10.1210/Jcem-53-1-117  0.463
1980 Thomas DA, McIntosh TK, Barfield RJ. Influence of androgen in the neonatal period on ejaculatory and postejaculatory behavior in the rat. Hormones and Behavior. 14: 153-62. PMID 7419168 DOI: 10.1016/0018-506X(80)90007-0  0.556
1980 Drickamer LC, McIntosh TK. Effects of adrenalectomy on the presence of a maturation-delaying pheromone in the urine of female mice. Hormones and Behavior. 14: 146-52. PMID 7419167 DOI: 10.1016/0018-506X(80)90006-9  0.517
1980 McIntosh TK, Vallano ML, Barfield RJ. Effects of morphine, beta-endorphin and naloxone on catecholamine levels and sexual behavior in the male rat. Pharmacology, Biochemistry, and Behavior. 13: 435-41. PMID 6252562 DOI: 10.1016/0091-3057(80)90251-8  0.551
1980 McIntosh TK, Barfield RJ. The temporal patterning of 40-60 kHz ultrasonic vocalizations and copulation in the rat (Rattus norvegicus) Behavioral and Neural Biology. 29: 349-358. DOI: 10.1016/S0163-1047(80)90259-9  0.544
1979 McIntosh TK, Davis PG, Barfield RJ. Urine marking and sexual behavior in the rat (Rattus norvegicus). Behavioral and Neural Biology. 26: 161-8. PMID 496777 DOI: 10.1016/S0163-1047(79)92531-7  0.555
1979 Barfield RJ, Auerbach P, Geyer LA, Mcintosh TK. Ultrasonic vocalizations in rat sexual behavior Integrative and Comparative Biology. 19: 469-480. DOI: 10.1093/Icb/19.2.469  0.545
1978 McIntosh TK, Barfield RJ, Geyer LA. Ultrasonic vocalisations facilitate sexual behaviour of female rats. Nature. 272: 163-4. PMID 628443 DOI: 10.1038/272163A0  0.554
1978 Drickamer LC, McIntosh TK, Rose EA. Effects of ovariectomy on the presence of a maturation-delaying pheromone in the urine of female mice. Hormones and Behavior. 11: 131-7. PMID 570953 DOI: 10.1016/0018-506X(78)90064-8  0.517
1978 Geyer LA, Barfield RJ, McIntosh TK. Influence of gonadal hormones and sexual behavior on ultrasonic vocalization in rats: II. Treatment of males Journal of Comparative and Physiological Psychology. 92: 447-456. DOI: 10.1037/h0077487  0.542
1978 Geyer LA, McIntosh TK, Barfield RJ. Effects of ultrasonic vocalizations and male's urine on female rat readiness to mate Journal of Comparative and Physiological Psychology. 92: 457-462. DOI: 10.1037/H0077478  0.542
1977 McIntosh TK, Drickamer LC. Excreted urine, bladder urine, and the delay of sexual maturation in female house mice. Animal Behaviour. 25: 999-1004. PMID 564151 DOI: 10.1016/0003-3472(77)90051-3  0.517
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