Tracy K. McIntosh - Publications

Affiliations: 
Media Neuroconsultants 

254 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Lifshitz J, Rowe RK, Griffiths DR, Evilsizor MN, Thomas TC, Adelson PD, McIntosh TK. Clinical relevance of midline fluid percussion brain injury: Acute deficits, chronic morbidities and the utility of biomarkers. Brain Injury. 1-9. PMID 27712117 DOI: 10.1080/02699052.2016.1193628  1
2012 Tomasevic G, Laurer HL, Mattiasson G, van Steeg H, Wieloch T, McIntosh TK. Delayed neuromotor recovery and increased memory acquisition dysfunction following experimental brain trauma in mice lacking the DNA repair gene XPA. Journal of Neurosurgery. 116: 1368-78. PMID 22462511 DOI: 10.3171/2012.2.JNS11888  1
2010 Tomasevic G, Raghupathi R, Scherbel U, Wieloch T, McIntosh TK. Deletion of the p53 tumor suppressor gene improves neuromotor function but does not attenuate regional neuronal cell loss following experimental brain trauma in mice. Journal of Neuroscience Research. 88: 3414-23. PMID 20890990 DOI: 10.1002/jnr.22491  1
2010 Vagnozzi R, Signoretti S, Cristofori L, Alessandrini F, Floris R, Isgrò E, Ria A, Marziali S, Marziale S, Zoccatelli G, Tavazzi B, Del Bolgia F, Sorge R, Broglio SP, McIntosh TK, et al. Assessment of metabolic brain damage and recovery following mild traumatic brain injury: a multicentre, proton magnetic resonance spectroscopic study in concussed patients. Brain : a Journal of Neurology. 133: 3232-42. PMID 20736189 DOI: 10.1093/brain/awq200  1
2010 HÃ¥nell A, Clausen F, Björk M, Jansson K, Philipson O, Nilsson LN, Hillered L, Weinreb PH, Lee D, McIntosh TK, Gimbel DA, Strittmatter SM, Marklund N. Genetic deletion and pharmacological inhibition of Nogo-66 receptor impairs cognitive outcome after traumatic brain injury in mice. Journal of Neurotrauma. 27: 1297-309. PMID 20486800 DOI: 10.1089/neu.2009.1255  1
2010 Longhi L, Zanier ER, Conte V, Stocchetti N, McIntosh TK. Vascular Issues in Neurodegeneration and Injury Encyclopedia of Neuroscience. 33-41. DOI: 10.1016/B978-008045046-9.00536-2  1
2009 Marklund N, Morales D, Clausen F, HÃ¥nell A, Kiwanuka O, Pitkänen A, Gimbel DA, Philipson O, Lannfelt L, Hillered L, Strittmatter SM, McIntosh TK. Functional outcome is impaired following traumatic brain injury in aging Nogo-A/B-deficient mice. Neuroscience. 163: 540-51. PMID 19555742 DOI: 10.1016/j.neuroscience.2009.06.042  1
2009 Longhi L, Perego C, Ortolano F, Zanier ER, Bianchi P, Stocchetti N, McIntosh TK, De Simoni MG. C1-inhibitor attenuates neurobehavioral deficits and reduces contusion volume after controlled cortical impact brain injury in mice. Critical Care Medicine. 37: 659-65. PMID 19114897 DOI: 10.1097/CCM.0b013e318195998a  1
2009 Mammis A, McIntosh TK, Maniker AH. Erythropoietin as a neuroprotective agent in traumatic brain injury Review. Surgical Neurology. 71: 527-31; discussion 5. PMID 18789503 DOI: 10.1016/j.surneu.2008.02.040  1
2008 Catrambone JE, He W, Prestigiacomo CJ, McIntosh TK, Carmel PW, Maniker A. The use of Hypertonic Saline in the Treatment of Post-Traumatic Cerebral Edema: A Review. European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society. 34: 397-409. PMID 26815818 DOI: 10.1007/s00068-007-7068-7  1
2008 Conte V, Raghupathi R, Watson DJ, Fujimoto S, Royo NC, Marklund N, Stocchetti N, McIntosh TK. TrkB gene transfer does not alter hippocampal neuronal loss and cognitive deficits following traumatic brain injury in mice. Restorative Neurology and Neuroscience. 26: 45-56. PMID 18431005  1
2007 Marklund N, Bareyre FM, Royo NC, Thompson HJ, Mir AK, Grady MS, Schwab ME, McIntosh TK. Cognitive outcome following brain injury and treatment with an inhibitor of Nogo-A in association with an attenuated downregulation of hippocampal growth-associated protein-43 expression. Journal of Neurosurgery. 107: 844-53. PMID 17937233 DOI: 10.3171/JNS-07/10/0844  1
2007 Keck CA, Thompson HJ, Pitkänen A, LeBold DG, Morales DM, Plevy JB, Puri R, Zhao B, Dichter M, McIntosh TK. The novel antiepileptic agent RWJ-333369-A, but not its analog RWJ-333369, reduces regional cerebral edema without affecting neurobehavioral outcome or cell death following experimental traumatic brain injury. Restorative Neurology and Neuroscience. 25: 77-90. PMID 17726266  1
2006 Thompson HJ, Marklund N, LeBold DG, Morales DM, Keck CA, Vinson M, Royo NC, Grundy R, McIntosh TK. Tissue sparing and functional recovery following experimental traumatic brain injury is provided by treatment with an anti-myelin-associated glycoprotein antibody. The European Journal of Neuroscience. 24: 3063-72. PMID 17156367 DOI: 10.1111/j.1460-9568.2006.05197.x  1
2006 Johnson VE, Murray L, Raghupathi R, Stewart J, Nicoll JA, MacKinnon MA, McIntosh TK, Graham DI. No evidence for the presence of apolipoprotein epsilon4, interleukin-lalpha allele 2 and interleukin-1beta allele 2 cause an increase in programmed cell death following traumatic brain injury in humans. Clinical Neuropathology. 25: 255-64. PMID 17140155  1
2006 Maxwell WL, MacKinnon MA, Smith DH, McIntosh TK, Graham DI. Thalamic nuclei after human blunt head injury. Journal of Neuropathology and Experimental Neurology. 65: 478-88. PMID 16772871 DOI: 10.1097/01.jnen.0000229241.28619.75  1
2006 Marklund N, Bakshi A, Castelbuono DJ, Conte V, McIntosh TK. Evaluation of pharmacological treatment strategies in traumatic brain injury. Current Pharmaceutical Design. 12: 1645-80. PMID 16729876 DOI: 10.2174/138161206776843340  1
2006 Thompson HJ, LeBold DG, Marklund N, Morales DM, Hagner AP, McIntosh TK. Cognitive evaluation of traumatically brain-injured rats using serial testing in the Morris water maze. Restorative Neurology and Neuroscience. 24: 109-14. PMID 16720946  1
2006 Kharatishvili I, Nissinen JP, McIntosh TK, Pitkänen A. A model of posttraumatic epilepsy induced by lateral fluid-percussion brain injury in rats. Neuroscience. 140: 685-97. PMID 16650603 DOI: 10.1016/j.neuroscience.2006.03.012  1
2006 Bakshi A, Shimizu S, Keck CA, Cho S, LeBold DG, Morales D, Arenas E, Snyder EY, Watson DJ, McIntosh TK. Neural progenitor cells engineered to secrete GDNF show enhanced survival, neuronal differentiation and improve cognitive function following traumatic brain injury. The European Journal of Neuroscience. 23: 2119-34. PMID 16630059 DOI: 10.1111/j.1460-9568.2006.04743.x  1
2006 Royo NC, Conte V, Saatman KE, Shimizu S, Belfield CM, Soltesz KM, Davis JE, Fujimoto ST, McIntosh TK. Hippocampal vulnerability following traumatic brain injury: a potential role for neurotrophin-4/5 in pyramidal cell neuroprotection. The European Journal of Neuroscience. 23: 1089-102. PMID 16553773 DOI: 10.1111/j.1460-9568.2006.04642.x  1
2006 Pitkänen A, McIntosh TK. Animal models of post-traumatic epilepsy. Journal of Neurotrauma. 23: 241-61. PMID 16503807 DOI: 10.1089/neu.2006.23.241  1
2006 Dubreuil CI, Marklund N, Deschamps K, McIntosh TK, McKerracher L. Activation of Rho after traumatic brain injury and seizure in rats. Experimental Neurology. 198: 361-9. PMID 16448651 DOI: 10.1016/j.expneurol.2005.12.002  1
2006 Yi JH, Hoover R, McIntosh TK, Hazell AS. Early, transient increase in complexin I and complexin II in the cerebral cortex following traumatic brain injury is attenuated by N-acetylcysteine. Journal of Neurotrauma. 23: 86-96. PMID 16430375 DOI: 10.1089/neu.2006.23.86  1
2006 Schütz C, Stover JF, Thompson HJ, Hoover RC, Morales DM, Schouten JW, McMillan A, Soltesz K, Motta M, Spangler Z, Neugebauer E, McIntosh TK. Acute, transient hemorrhagic hypotension does not aggravate structural damage or neurologic motor deficits but delays the long-term cognitive recovery following mild to moderate traumatic brain injury. Critical Care Medicine. 34: 492-501. PMID 16424733 DOI: 10.1097/01.CCM.0000198326.32049.7F  1
2006 Marklund N, Fulp CT, Shimizu S, Puri R, McMillan A, Strittmatter SM, McIntosh TK. Selective temporal and regional alterations of Nogo-A and small proline-rich repeat protein 1A (SPRR1A) but not Nogo-66 receptor (NgR) occur following traumatic brain injury in the rat. Experimental Neurology. 197: 70-83. PMID 16321384 DOI: 10.1016/j.expneurol.2005.08.029  1
2006 Lifshitz J, Janmey PA, McIntosh TK. Photon correlation spectroscopy of brain mitochondrial populations: application to traumatic brain injury. Experimental Neurology. 197: 318-29. PMID 16289540 DOI: 10.1016/j.expneurol.2005.10.002  1
2006 Pitkänen A, Kharatishvili I, Nissinen J, McIntosh TK. Posttraumatic Epilepsy Induced by Lateral Fluid-Percussion Brain Injury in Rats Models of Seizures and Epilepsy. 465-476. DOI: 10.1016/B978-012088554-1/50039-6  1
2005 Longhi L, Zanier ER, Royo N, Stocchetti N, McIntosh TK. Stem cell transplantation as a therapeutic strategy for traumatic brain injury. Transplant Immunology. 15: 143-8. PMID 16412958 DOI: 10.1016/j.trim.2005.09.003  1
2005 Zhang C, Saatman KE, Royo NC, Soltesz KM, Millard M, Schouten JW, Motta M, Hoover RC, McMillan A, Watson DJ, Lee VM, Trojanowski JQ, McIntosh TK. Delayed transplantation of human neurons following brain injury in rats: a long-term graft survival and behavior study. Journal of Neurotrauma. 22: 1456-74. PMID 16379583 DOI: 10.1089/neu.2005.22.1456  1
2005 Bakshi A, Keck CA, Koshkin VS, LeBold DG, Siman R, Snyder EY, McIntosh TK. Caspase-mediated cell death predominates following engraftment of neural progenitor cells into traumatically injured rat brain. Brain Research. 1065: 8-19. PMID 16309635 DOI: 10.1016/j.brainres.2005.09.059  1
2005 Morales DM, Marklund N, Lebold D, Thompson HJ, Pitkanen A, Maxwell WL, Longhi L, Laurer H, Maegele M, Neugebauer E, Graham DI, Stocchetti N, McIntosh TK. Experimental models of traumatic brain injury: do we really need to build a better mousetrap? Neuroscience. 136: 971-89. PMID 16242846 DOI: 10.1016/j.neuroscience.2005.08.030  1
2005 Emery DL, Fulp CT, Saatman KE, Schütz C, Neugebauer E, McIntosh TK. Newly born granule cells in the dentate gyrus rapidly extend axons into the hippocampal CA3 region following experimental brain injury. Journal of Neurotrauma. 22: 978-88. PMID 16156713 DOI: 10.1089/neu.2005.22.978  1
2005 Enomoto T, Osugi T, Satoh H, McIntosh TK, Nabeshima T. Pre-Injury magnesium treatment prevents traumatic brain injury-induced hippocampal ERK activation, neuronal loss, and cognitive dysfunction in the radial-arm maze test. Journal of Neurotrauma. 22: 783-92. PMID 16004581 DOI: 10.1089/neu.2005.22.783  1
2005 Maegele M, Lippert-Gruener M, Ester-Bode T, Sauerland S, Schäfer U, Molcanyi M, Molcany M, Lefering R, Bouillon B, Neiss WF, Angelov DN, Klug N, McIntosh TK, Neugebauer EA. Reversal of neuromotor and cognitive dysfunction in an enriched environment combined with multimodal early onset stimulation after traumatic brain injury in rats. Journal of Neurotrauma. 22: 772-82. PMID 16004580 DOI: 10.1089/neu.2005.22.772  1
2005 Lenzlinger PM, Shimizu S, Marklund N, Thompson HJ, Schwab ME, Saatman KE, Hoover RC, Bareyre FM, Motta M, Luginbuhl A, Pape R, Clouse AK, Morganti-Kossmann C, McIntosh TK. Delayed inhibition of Nogo-A does not alter injury-induced axonal sprouting but enhances recovery of cognitive function following experimental traumatic brain injury in rats. Neuroscience. 134: 1047-56. PMID 15979242 DOI: 10.1016/j.neuroscience.2005.04.048  1
2005 Marklund N, Keck C, Hoover R, Soltesz K, Millard M, LeBold D, Spangler Z, Banning A, Benson J, McIntosh TK. Administration of monoclonal antibodies neutralizing the inflammatory mediators tumor necrosis factor alpha and interleukin -6 does not attenuate acute behavioral deficits following experimental traumatic brain injury in the rat. Restorative Neurology and Neuroscience. 23: 31-42. PMID 15846030  1
2005 Maegele M, Riess P, Sauerland S, Bouillon B, Hess S, McIntosh TK, Mautes A, Brockmann M, Koebke J, Knifka J, Neugebauer EA. Characterization of a new rat model of experimental combined neurotrauma. Shock (Augusta, Ga.). 23: 476-81. PMID 15834316 DOI: 10.1097/01.shk.0000159929.87737.5c  1
2005 Longhi L, Saatman KE, Fujimoto S, Raghupathi R, Meaney DF, Davis J, McMillan B S A, Conte V, Laurer HL, Stein S, Stocchetti N, McIntosh TK. Temporal window of vulnerability to repetitive experimental concussive brain injury. Neurosurgery. 56: 364-74; discussion 3. PMID 15670384 DOI: 10.1227/01.NEU.0000149008.73513.44  1
2005 Thompson HJ, Lifshitz J, Marklund N, Grady MS, Graham DI, Hovda DA, McIntosh TK. Lateral fluid percussion brain injury: a 15-year review and evaluation. Journal of Neurotrauma. 22: 42-75. PMID 15665602 DOI: 10.1089/neu.2005.22.42  1
2005 Thompson HJ, Hoover RC, Tkacs NC, Saatman KE, McIntosh TK. Development of posttraumatic hyperthermia after traumatic brain injury in rats is associated with increased periventricular inflammation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 163-76. PMID 15647747 DOI: 10.1038/sj.jcbfm.9600008  1
2005 Pitkänen A, Longhi L, Marklund N, Morales DM, McIntosh TK. Neurodegeneration and neuroprotective strategies after traumatic brain injury Drug Discovery Today: Disease Mechanisms. 2: 409-418. DOI: 10.1016/j.ddmec.2005.11.011  1
2004 Lifshitz J, Sullivan PG, Hovda DA, Wieloch T, McIntosh TK. Mitochondrial damage and dysfunction in traumatic brain injury. Mitochondrion. 4: 705-13. PMID 16120426 DOI: 10.1016/j.mito.2004.07.021  1
2004 Longhi L, Watson DJ, Saatman KE, Thompson HJ, Zhang C, Fujimoto S, Royo N, Castelbuono D, Raghupathi R, Trojanowski JQ, Lee VM, Wolfe JH, Stocchetti N, McIntosh TK. Ex vivo gene therapy using targeted engraftment of NGF-expressing human NT2N neurons attenuates cognitive deficits following traumatic brain injury in mice. Journal of Neurotrauma. 21: 1723-36. PMID 15684764 DOI: 10.1089/neu.2004.21.1723  1
2004 Schouten JW, Fulp CT, Royo NC, Saatman KE, Watson DJ, Snyder EY, Trojanowski JQ, Prockop DJ, Maas AI, McIntosh TK. A review and rationale for the use of cellular transplantation as a therapeutic strategy for traumatic brain injury. Journal of Neurotrauma. 21: 1501-38. PMID 15684646 DOI: 10.1089/neu.2004.21.1501  1
2004 Maxwell WL, Pennington K, MacKinnon MA, Smith DH, McIntosh TK, Wilson JT, Graham DI. Differential responses in three thalamic nuclei in moderately disabled, severely disabled and vegetative patients after blunt head injury. Brain : a Journal of Neurology. 127: 2470-8. PMID 15456707 DOI: 10.1093/brain/awh294  1
2004 Fujimoto ST, Longhi L, Saatman KE, Conte V, Stocchetti N, McIntosh TK. Motor and cognitive function evaluation following experimental traumatic brain injury. Neuroscience and Biobehavioral Reviews. 28: 365-78. PMID 15341032 DOI: 10.1016/j.neubiorev.2004.06.002  1
2004 Lenzlinger PM, Saatman KE, Hoover RC, Cheney JA, Bareyre FM, Raghupathi R, Arnold LD, McIntosh TK. Inhibition of vascular endothelial growth factor receptor (VEGFR) signaling by BSF476921 attenuates regional cerebral edema following traumatic brain injury in rats. Restorative Neurology and Neuroscience. 22: 73-9. PMID 15272142  1
2004 Conte V, Uryu K, Fujimoto S, Yao Y, Rokach J, Longhi L, Trojanowski JQ, Lee VM, McIntosh TK, Praticò D. Vitamin E reduces amyloidosis and improves cognitive function in Tg2576 mice following repetitive concussive brain injury. Journal of Neurochemistry. 90: 758-64. PMID 15255955 DOI: 10.1111/j.1471-4159.2004.02560.x  1
2004 Otori T, Friedland JC, Sinson G, McIntosh TK, Raghupathi R, Welsh FA. Traumatic brain injury elevates glycogen and induces tolerance to ischemia in rat brain. Journal of Neurotrauma. 21: 707-18. PMID 15253799 DOI: 10.1089/0897715041269623  1
2004 Siman R, McIntosh TK, Soltesz KM, Chen Z, Neumar RW, Roberts VL. Proteins released from degenerating neurons are surrogate markers for acute brain damage. Neurobiology of Disease. 16: 311-20. PMID 15193288 DOI: 10.1016/j.nbd.2004.03.016  1
2004 Davis JE, Eberwine JH, Hinkle DA, Marciano PG, Meaney DF, McIntosh TK. Methodological considerations regarding single-cell gene expression profiling for brain injury. Neurochemical Research. 29: 1113-21. PMID 15176468 DOI: 10.1023/B:NERE.0000023598.04937.83  1
2004 Hoover RC, Motta M, Davis J, Saatman KE, Fujimoto ST, Thompson HJ, Stover JF, Dichter MA, Twyman R, White HS, McIntosh TK. Differential effects of the anticonvulsant topiramate on neurobehavioral and histological outcomes following traumatic brain injury in rats. Journal of Neurotrauma. 21: 501-12. PMID 15165359 DOI: 10.1089/089771504774129847  1
2004 Wilson S, Raghupathi R, Saatman KE, MacKinnon MA, McIntosh TK, Graham DI. Continued in situ DNA fragmentation of microglia/macrophages in white matter weeks and months after traumatic brain injury. Journal of Neurotrauma. 21: 239-50. PMID 15115599 DOI: 10.1089/089771504322972031  1
2004 Marciano PG, Brettschneider J, Manduchi E, Davis JE, Eastman S, Raghupathi R, Saatman KE, Speed TP, Stoeckert CJ, Eberwine JH, McIntosh TK. Neuron-specific mRNA complexity responses during hippocampal apoptosis after traumatic brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2866-76. PMID 15044525 DOI: 10.1523/JNEUROSCI.5051-03.2004  1
2003 Emery DL, Royo NC, Fischer I, Saatman KE, McIntosh TK. Plasticity following injury to the adult central nervous system: is recapitulation of a developmental state worth promoting? Journal of Neurotrauma. 20: 1271-92. PMID 14748977 DOI: 10.1089/089771503322686085  1
2003 Boockvar JA, Kapitonov D, Kapoor G, Schouten J, Counelis GJ, Bogler O, Snyder EY, McIntosh TK, O'Rourke DM. Constitutive EGFR signaling confers a motile phenotype to neural stem cells. Molecular and Cellular Neurosciences. 24: 1116-30. PMID 14697673 DOI: 10.1016/j.mcn.2003.09.011  1
2003 Raghupathi R, Muir JK, Fulp CT, Pittman RN, McIntosh TK. Acute activation of mitogen-activated protein kinases following traumatic brain injury in the rat: implications for posttraumatic cell death. Experimental Neurology. 183: 438-48. PMID 14552884 DOI: 10.1016/S0014-4886(03)00166-3  1
2003 Wagner OI, Lifshitz J, Janmey PA, Linden M, McIntosh TK, Leterrier JF. Mechanisms of mitochondria-neurofilament interactions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9046-58. PMID 14534238  1
2003 Smith DH, Uryu K, Saatman KE, Trojanowski JQ, McIntosh TK. Protein accumulation in traumatic brain injury. Neuromolecular Medicine. 4: 59-72. PMID 14528053 DOI: 10.1385/NMM:4:1-2:59  1
2003 Royo NC, Schouten JW, Fulp CT, Shimizu S, Marklund N, Graham DI, McIntosh TK. From cell death to neuronal regeneration: building a new brain after traumatic brain injury. Journal of Neuropathology and Experimental Neurology. 62: 801-11. PMID 14503636  1
2003 Raghupathi R, Strauss KI, Zhang C, Krajewski S, Reed JC, McIntosh TK. Temporal alterations in cellular Bax:Bcl-2 ratio following traumatic brain injury in the rat. Journal of Neurotrauma. 20: 421-35. PMID 12803975 DOI: 10.1089/089771503765355504  1
2003 Thompson HJ, Tkacs NC, Saatman KE, Raghupathi R, McIntosh TK. Hyperthermia following traumatic brain injury: a critical evaluation. Neurobiology of Disease. 12: 163-73. PMID 12742737 DOI: 10.1016/S0969-9961(02)00030-X  1
2003 Watson DJ, Longhi L, Lee EB, Fulp CT, Fujimoto S, Royo NC, Passini MA, Trojanowski JQ, Lee VM, McIntosh TK, Wolfe JH. Genetically modified NT2N human neuronal cells mediate long-term gene expression as CNS grafts in vivo and improve functional cognitive outcome following experimental traumatic brain injury. Journal of Neuropathology and Experimental Neurology. 62: 368-80. PMID 12722829  1
2003 Lifshitz J, McIntosh TK. Age-associated mitochondrial DNA deletions are not evident chronically after experimental brain injury in the rat. Journal of Neurotrauma. 20: 139-49. PMID 12675968 DOI: 10.1089/08977150360547062  1
2003 Lifshitz J, Friberg H, Neumar RW, Raghupathi R, Welsh FA, Janmey P, Saatman KE, Wieloch T, Grady MS, McIntosh TK. Structural and functional damage sustained by mitochondria after traumatic brain injury in the rat: evidence for differentially sensitive populations in the cortex and hippocampus. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 219-31. PMID 12571453  1
2003 Royo NC, Shimizu S, Schouten JW, Stover JF, McIntosh TK. Pharmacology of traumatic brain injury. Current Opinion in Pharmacology. 3: 27-32. PMID 12550738 DOI: 10.1016/S1471-4892(02)00006-1  1
2003 Conte V, Royo NC, Shimizu S, Saatman KE, Watson DJ, Graham DI, Stocchetti N, McIntosh TK. Neurotrophic Factors: Pathophysiology and Therapeutic Applications in Traumatic Brain Injury European Journal of Trauma. 29: 335-355. DOI: 10.1007/s00068-003-1335-z  1
2002 Kelz MB, Dent GW, Therianos S, Marciano PG, McIntosh TK, Coleman PD, Eberwine JH. Single-cell antisense RNA amplification and microarray analysis as a tool for studying neurological degeneration and restoration. Science of Aging Knowledge Environment : Sage Ke. 2002: re1. PMID 14602975 DOI: 10.1126/sageke.2002.1.re1  0.64
2002 Iwata A, Chen XH, McIntosh TK, Browne KD, Smith DH. Long-term accumulation of amyloid-beta in axons following brain trauma without persistent upregulation of amyloid precursor protein genes. Journal of Neuropathology and Experimental Neurology. 61: 1056-68. PMID 12484568  1
2002 Marciano PG, Eberwine JH, Ragupathi R, Saatman KE, Meaney DF, McIntosh TK. Expression profiling following traumatic brain injury: a review. Neurochemical Research. 27: 1147-55. PMID 12462413 DOI: 10.1023/A:1020973308941  1
2002 Hartman RE, Laurer H, Longhi L, Bales KR, Paul SM, McIntosh TK, Holtzman DM. Apolipoprotein E4 influences amyloid deposition but not cell loss after traumatic brain injury in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10083-7. PMID 12451108  1
2002 Leclercq PD, Stephenson MS, Murray LS, McIntosh TK, Graham DI, Gentleman SM. Simple morphometry of axonal swellings cannot be used in isolation for dating lesions after traumatic brain injury. Journal of Neurotrauma. 19: 1183-92. PMID 12427327 DOI: 10.1089/08977150260337985  1
2002 Riess P, Zhang C, Saatman KE, Laurer HL, Longhi LG, Raghupathi R, Lenzlinger PM, Lifshitz J, Boockvar J, Neugebauer E, Snyder EY, McIntosh TK. Transplanted neural stem cells survive, differentiate, and improve neurological motor function after experimental traumatic brain injury. Neurosurgery. 51: 1043-52; discussion . PMID 12234415 DOI: 10.1097/00006123-200210000-00035  1
2002 Fowler J, MacKinnon MA, Raghupathi R, Saatman KE, McIntosh TK, Graham DI. Age does not influence DNA fragmentation in the hippocampus after fatal traumatic brain injury in young and aged humans compared with controls. Clinical Neuropathology. 21: 156-62. PMID 12143927  1
2002 Narayan RK, Michel ME, Ansell B, Baethmann A, Biegon A, Bracken MB, Bullock MR, Choi SC, Clifton GL, Contant CF, Coplin WM, Dietrich WD, Ghajar J, Grady SM, Grossman RG, ... ... McIntosh TK, et al. Clinical trials in head injury. Journal of Neurotrauma. 19: 503-57. PMID 12042091 DOI: 10.1089/089771502753754037  1
2002 Praticò D, Reiss P, Tang LX, Sung S, Rokach J, McIntosh TK. Local and systemic increase in lipid peroxidation after moderate experimental traumatic brain injury. Journal of Neurochemistry. 80: 894-8. PMID 11948253 DOI: 10.1046/j.0022-3042.2002.00777.x  1
2002 Raghupathi R, Conti AC, Graham DI, Krajewski S, Reed JC, Grady MS, Trojanowski JQ, McIntosh TK. Mild traumatic brain injury induces apoptotic cell death in the cortex that is preceded by decreases in cellular Bcl-2 immunoreactivity. Neuroscience. 110: 605-16. PMID 11934469 DOI: 10.1016/S0306-4522(01)00461-4  1
2001 Marciano P, Eberwine JH, Raghupathi R, McIntosh TK. The assessment of genomic alterations using DNA arrays following traumatic brain injury: a review. Restorative Neurology and Neuroscience. 18: 105-13. PMID 11847433  1
2001 Lenzlinger PM, Morganti-Kossmann MC, Laurer HL, McIntosh TK. The duality of the inflammatory response to traumatic brain injury. Molecular Neurobiology. 24: 169-81. PMID 11831551 DOI: 10.1385/MN:24:1-3:169  1
2001 Williams S, Raghupathi R, MacKinnon MA, McIntosh TK, Saatman KE, Graham DI. In situ DNA fragmentation occurs in white matter up to 12 months after head injury in man. Acta Neuropathologica. 102: 581-90. PMID 11761718  1
2001 Laurer HL, Bareyre FM, Lee VM, Trojanowski JQ, Longhi L, Hoover R, Saatman KE, Raghupathi R, Hoshino S, Grady MS, McIntosh TK. Mild head injury increasing the brain's vulnerability to a second concussive impact. Journal of Neurosurgery. 95: 859-70. PMID 11702878 DOI: 10.3171/jns.2001.95.5.0859  1
2001 Longhi L, Saatman KE, Raghupathi R, Laurer HL, Lenzlinger PM, Riess P, Neugebauer E, Trojanowski JQ, Lee VM, Grady MS, Graham DI, McIntosh TK. A review and rationale for the use of genetically engineered animals in the study of traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 21: 1241-58. PMID 11702040 DOI: 10.1097/00004647-200111000-00001  1
2001 Riess P, Bareyre FM, Saatman KE, Cheney JA, Lifshitz J, Raghupathi R, Grady MS, Neugebauer E, McIntosh TK. Effects of chronic, post-injury Cyclosporin A administration on motor and sensorimotor function following severe, experimental traumatic brain injury. Restorative Neurology and Neuroscience. 18: 1-8. PMID 11673665  1
2001 Laurer HL, McIntosh TK. Pharmacologic therapy in traumatic brain injury: update on experimental treatment strategies. Current Pharmaceutical Design. 7: 1505-16. PMID 11562295 DOI: 10.2174/1381612013397285  1
2001 Marklund N, Clausen F, McIntosh TK, Hillered L. Free radical scavenger posttreatment improves functional and morphological outcome after fluid percussion injury in the rat. Journal of Neurotrauma. 18: 821-32. PMID 11526988 DOI: 10.1089/089771501316919184  1
2001 Shaw K, MacKinnon MA, Raghupathi R, Saatman KE, Mclntosh TK, Graham DI. TUNEL-positive staining in white and grey matter after fatal head injury in man. Clinical Neuropathology. 20: 106-12. PMID 11430493  1
2001 Philips MF, Mattiasson G, Wieloch T, Björklund A, Johansson BB, Tomasevic G, Martínez-Serrano A, Lenzlinger PM, Sinson G, Grady MS, McIntosh TK. Neuroprotective and behavioral efficacy of nerve growth factor-transfected hippocampal progenitor cell transplants after experimental traumatic brain injury. Journal of Neurosurgery. 94: 765-74. PMID 11354408 DOI: 10.3171/jns.2001.94.5.0765  1
2001 LaPlaca MC, Zhang J, Raghupathi R, Li JH, Smith F, Bareyre FM, Snyder SH, Graham DI, McIntosh TK. Pharmacologic inhibition of poly(ADP-ribose) polymerase is neuroprotective following traumatic brain injury in rats. Journal of Neurotrauma. 18: 369-76. PMID 11336438 DOI: 10.1089/089771501750170912  1
2001 Cheney JA, Weisser JD, Bareyre FM, Laurer HL, Saatman KE, Raghupathi R, Gribkoff V, Starrett JE, McIntosh TK. The maxi-K channel opener BMS-204352 attenuates regional cerebral edema and neurologic motor impairment after experimental brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 21: 396-403. PMID 11323525 DOI: 10.1097/00004647-200104000-00008  1
2001 Bentzer P, Mattiasson G, McIntosh TK, Wieloch T, Grande PO. Infusion of prostacyclin following experimental brain injury in the rat reduces cortical lesion volume. Journal of Neurotrauma. 18: 275-85. PMID 11284548 DOI: 10.1089/08977150151070919  1
2001 Bareyre FM, Raghupathi R, Saatman KE, McIntosh TK. DNase I disinhibition is predominantly associated with actin hyperpolymerization after traumatic brain injury. Journal of Neurochemistry. 77: 173-81. PMID 11279273 DOI: 10.1046/j.1471-4159.2001.00215.x  1
2001 Saatman KE, Bareyre FM, Grady MS, McIntosh TK. Acute cytoskeletal alterations and cell death induced by experimental brain injury are attenuated by magnesium treatment and exacerbated by magnesium deficiency. Journal of Neuropathology and Experimental Neurology. 60: 183-94. PMID 11273006  1
2001 Sinson G, Bagley LJ, Cecil KM, Torchia M, McGowan JC, Lenkinski RE, McIntosh TK, Grossman RI. Magnetization transfer imaging and proton MR spectroscopy in the evaluation of axonal injury: correlation with clinical outcome after traumatic brain injury. Ajnr. American Journal of Neuroradiology. 22: 143-51. PMID 11158900  1
2000 O'Dell DM, Muir JK, Zhang C, Bareyre FM, Saatman KE, Raghupathi R, Welsh F, McIntosh TK. Lubeluzole treatment does not attenuate neurobehavioral dysfunction or CA3 hippocampal neuronal loss following traumatic brain injury in rats. Restorative Neurology and Neuroscience. 16: 127-134. PMID 12671215  1
2000 Bareyre FM, Saatman KE, Raghupathi R, McIntosh TK. Postinjury treatment with magnesium chloride attenuates cortical damage after traumatic brain injury in rats. Journal of Neurotrauma. 17: 1029-39. PMID 11101206  1
2000 Leoni MJ, Chen XH, Mueller AL, Cheney J, McIntosh TK, Smith DH. NPS 1506 attenuates cognitive dysfunction and hippocampal neuron death following brain trauma in the rat. Experimental Neurology. 166: 442-9. PMID 11085909 DOI: 10.1006/exnr.2000.7513  1
2000 Raghupathi R, Graham DI, McIntosh TK. Apoptosis after traumatic brain injury. Journal of Neurotrauma. 17: 927-38. PMID 11063058  1
2000 Smith FM, Raghupathi R, MacKinnon MA, McIntosh TK, Saatman KE, Meaney DF, Graham DI. TUNEL-positive staining of surface contusions after fatal head injury in man. Acta Neuropathologica. 100: 537-45. PMID 11045676 DOI: 10.1007/s004010000222  1
2000 Blaha GR, Raghupathi R, Saatman KE, McIntosh TK. Brain-derived neurotrophic factor administration after traumatic brain injury in the rat does not protect against behavioral or histological deficits. Neuroscience. 99: 483-93. PMID 11029540 DOI: 10.1016/S0306-4522(00)00214-1  1
2000 Galvin JE, Nakamura M, McIntosh TK, Saatman KE, Sampathu D, Raghupathi R, Lee VM, Trojanowski JQ. Neurofilament-rich intraneuronal inclusions exacerbate neurodegenerative sequelae of brain trauma in NFH/LacZ transgenic mice. Experimental Neurology. 165: 77-89. PMID 10964487 DOI: 10.1006/exnr.2000.7461  1
2000 Graham DI, McIntosh TK, Maxwell WL, Nicoll JA. Recent advances in neurotrauma. Journal of Neuropathology and Experimental Neurology. 59: 641-51. PMID 10952055  1
2000 Morrison B, Meaney DF, Margulies SS, McIntosh TK. Dynamic mechanical stretch of organotypic brain slice cultures induces differential genomic expression: relationship to mechanical parameters. Journal of Biomechanical Engineering. 122: 224-30. PMID 10923289 DOI: 10.1115/1.429650  1
2000 Emery DL, Raghupathi R, Saatman KE, Fischer I, Grady MS, McIntosh TK. Bilateral growth-related protein expression suggests a transient increase in regenerative potential following brain trauma. The Journal of Comparative Neurology. 424: 521-31. PMID 10906717 DOI: 10.1002/1096-9861(20000828)424:3<521::AID-CNE9>3.0.CO;2-8  1
2000 O'Dell DM, Raghupathi R, Crino PB, Eberwine JH, McIntosh TK. Traumatic brain injury alters the molecular fingerprint of TUNEL-positive cortical neurons In vivo: A single-cell analysis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 4821-8. PMID 10864939  1
2000 Nakagawa Y, Reed L, Nakamura M, McIntosh TK, Smith DH, Saatman KE, Raghupathi R, Clemens J, Saido TC, Lee VM, Trojanowski JQ. Brain trauma in aged transgenic mice induces regression of established abeta deposits. Experimental Neurology. 163: 244-52. PMID 10785464 DOI: 10.1006/exnr.2000.7375  1
2000 Mattiasson GJ, Philips MF, Tomasevic G, Johansson BB, Wieloch T, McIntosh TK. The rotating pole test: evaluation of its effectiveness in assessing functional motor deficits following experimental head injury in the rat. Journal of Neuroscience Methods. 95: 75-82. PMID 10776817 DOI: 10.1016/S0165-0270(99)00162-4  1
2000 Morrison B, Eberwine JH, Meaney DF, McIntosh TK. Traumatic injury induces differential expression of cell death genes in organotypic brain slice cultures determined by complementary DNA array hybridization. Neuroscience. 96: 131-9. PMID 10683418 DOI: 10.1016/S0306-4522(99)00537-0  1
2000 Bagley LJ, McGowan JC, Grossman RI, Sinson G, Kotapka M, Lexa FJ, Berlin JA, McIntosh TK. Magnetization transfer imaging of traumatic brain injury. Journal of Magnetic Resonance Imaging : Jmri. 11: 1-8. PMID 10676614 DOI: 10.1002/(SICI)1522-2586(200001)11:1<1::AID-JMRI1>3.0.CO;2-H  1
2000 Graham DI, Raghupathi R, Saatman KE, Meaney D, McIntosh TK. Tissue tears in the white matter after lateral fluid percussion brain injury in the rat: relevance to human brain injury. Acta Neuropathologica. 99: 117-24. PMID 10672317  1
2000 Saatman KE, Zhang C, Bartus RT, McIntosh TK. Behavioral efficacy of posttraumatic calpain inhibition is not accompanied by reduced spectrin proteolysis, cortical lesion, or apoptosis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 66-73. PMID 10616794 DOI: 10.1097/00004647-200001000-00010  1
2000 Laurer HL, Lenzlinger PM, McIntosh TK. Models of traumatic brain injury European Journal of Trauma. 26: 95-110. DOI: 10.1007/s000680050007  1
1999 Laurer HL, McIntosh TK. Experimental models of brain trauma. Current Opinion in Neurology. 12: 715-21. PMID 10676754 DOI: 10.1097/00019052-199912000-00010  1
1999 Nonaka M, Chen XH, Pierce JE, Leoni MJ, McIntosh TK, Wolf JA, Smith DH. Prolonged activation of NF-kappaB following traumatic brain injury in rats. Journal of Neurotrauma. 16: 1023-34. PMID 10595819  1
1999 O'Dell DM, McIntosh TK, Eberwine JH. Single-cell molecular biology: implications for the diagnosis and treatment of neurological disease. Archives of Neurology. 56: 1453-6. PMID 10593299  1
1999 Sanderson KL, Raghupathi R, Saatman KE, Martin D, Miller G, McIntosh TK. Interleukin-1 receptor antagonist attenuates regional neuronal cell death and cognitive dysfunction after experimental brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 19: 1118-25. PMID 10532636 DOI: 10.1097/00004647-199910000-00008  1
1999 Muir JK, Raghupathi R, Emery DL, Bareyre FM, McIntosh TK. Postinjury magnesium treatment attenuates traumatic brain injury-induced cortical induction of p53 mRNA in rats. Experimental Neurology. 159: 584-93. PMID 10506531 DOI: 10.1006/exnr.1999.7187  1
1999 Zhang C, Raghupathi R, Saatman KE, LaPlaca MC, McIntosh TK. Regional and temporal alterations in DNA fragmentation factor (DFF)-like proteins following experimental brain trauma in the rat. Journal of Neurochemistry. 73: 1650-9. PMID 10501212 DOI: 10.1046/j.1471-4159.1999.0731650.x  1
1999 Nakamura M, Raghupathi R, Merry DE, Scherbel U, Saatman KE, Mcintosh TK. Overexpression of Bcl-2 is neuroprotective after experimental brain injury in transgenic mice. The Journal of Comparative Neurology. 412: 681-92. PMID 10464363 DOI: 10.1002/(SICI)1096-9861(19991004)412:4<681::AID-CNE9>3.0.CO;2-F  1
1999 Nakagawa Y, Nakamura M, McIntosh TK, Rodriguez A, Berlin JA, Smith DH, Saatman KE, Raghupathi R, Clemens J, Saido TC, Schmidt ML, Lee VM, Trojanowski JQ. Traumatic brain injury in young, amyloid-beta peptide overexpressing transgenic mice induces marked ipsilateral hippocampal atrophy and diminished Abeta deposition during aging. The Journal of Comparative Neurology. 411: 390-8. PMID 10413774 DOI: 10.1002/(SICI)1096-9861(19990830)411:3<390::AID-CNE3>3.0.CO;2-#  1
1999 Philips MF, Muir JK, Saatman KE, Raghupathi R, Lee VM, Trojanowski JQ, McIntosh TK. Survival and integration of transplanted postmitotic human neurons following experimental brain injury in immunocompetent rats. Journal of Neurosurgery. 90: 116-24. PMID 10413164 DOI: 10.3171/jns.1999.90.1.0116  1
1999 Nakamura M, Saatman KE, Galvin JE, Scherbel U, Raghupathi R, Trojanowski JQ, McIntosh TK. Increased vulnerability of NFH-LacZ transgenic mouse to traumatic brain injury-induced behavioral deficits and cortical damage. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 19: 762-70. PMID 10413031 DOI: 10.1097/00004647-199907000-00006  1
1999 Scherbel U, Raghupathi R, Nakamura M, Saatman KE, Trojanowski JQ, Neugebauer E, Marino MW, McIntosh TK. Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury. Proceedings of the National Academy of Sciences of the United States of America. 96: 8721-6. PMID 10411942 DOI: 10.1073/pnas.96.15.8721  1
1999 Napieralski JA, Raghupathi R, McIntosh TK. The tumor-suppressor gene, p53, is induced in injured brain regions following experimental traumatic brain injury. Brain Research. Molecular Brain Research. 71: 78-86. PMID 10407189 DOI: 10.1016/S0169-328X(99)00155-2  1
1999 Hill-Felberg SJ, McIntosh TK, Oliver DL, Raghupathi R, Barbarese E. Concurrent loss and proliferation of astrocytes following lateral fluid percussion brain injury in the adult rat. Journal of Neuroscience Research. 57: 271-9. PMID 10398305 DOI: 10.1002/(SICI)1097-4547(19990715)57:2<271::AID-JNR13>3.0.CO;2-Z  1
1999 Bareyre FM, Saatman KE, Helfaer MA, Sinson G, Weisser JD, Brown AL, McIntosh TK. Alterations in ionized and total blood magnesium after experimental traumatic brain injury: relationship to neurobehavioral outcome and neuroprotective efficacy of magnesium chloride. Journal of Neurochemistry. 73: 271-80. PMID 10386980 DOI: 10.1046/j.1471-4159.1999.0730271.x  1
1999 LaPlaca MC, Raghupathi R, Verma A, Pieper AA, Saatman KE, Snyder SH, McIntosh TK. Temporal patterns of poly(ADP-ribose) polymerase activation in the cortex following experimental brain injury in the rat. Journal of Neurochemistry. 73: 205-13. PMID 10386972 DOI: 10.1046/j.1471-4159.1999.0730205.x  1
1999 Chen XH, Meaney DF, Xu BN, Nonaka M, McIntosh TK, Wolf JA, Saatman KE, Smith DH. Evolution of neurofilament subtype accumulation in axons following diffuse brain injury in the pig. Journal of Neuropathology and Experimental Neurology. 58: 588-96. PMID 10374749  1
1999 Muir JK, Raghupathi R, Saatman KE, Wilson CA, Lee VM, Trojanowski JQ, Philips MF, McIntosh TK. Terminally differentiated human neurons survive and integrate following transplantation into the traumatically injured rat brain. Journal of Neurotrauma. 16: 403-14. PMID 10369560  1
1999 McGowan JC, McCormack TM, Grossman RI, Mendonça R, Chen XH, Berlin JA, Meaney DF, Xu BN, Cecil KM, McIntosh TK, Smith DH. Diffuse axonal pathology detected with magnetization transfer imaging following brain injury in the pig. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 41: 727-33. PMID 10332848 DOI: 10.1002/(SICI)1522-2594(199904)41:4<727::AID-MRM11>3.0.CO;2-6  1
1999 Guluma KZ, Saatman KE, Brown A, Raghupathi R, McIntosh TK. Sequential pharmacotherapy with magnesium chloride and basic fibroblast growth factor after fluid percussion brain injury results in less neuromotor efficacy than that achieved with magnesium alone. Journal of Neurotrauma. 16: 311-21. PMID 10225217  1
1999 Gentleman SM, McKenzie JE, Royston MC, McIntosh TK, Graham DI. A comparison of manual and semi-automated methods in the assessment of axonal injury. Neuropathology and Applied Neurobiology. 25: 41-7. PMID 10194774  1
1999 Shreiber DI, Bain AC, Ross DT, Smith DH, Gennarelli TA, McIntosh TK, Meaney DF. Experimental investigation of cerebral contusion: histopathological and immunohistochemical evaluation of dynamic cortical deformation. Journal of Neuropathology and Experimental Neurology. 58: 153-64. PMID 10029098  1
1999 Ragnarsson KT, Clarke WR, Daling JR, Garber SL, Gustafson CF, Holland AL, Jordan BD, Parker JC, Riddle MA, Roth EJ, Seltzer MM, Simpson KN, Therrien B, Wexler BE, Yawn BP, ... ... McIntosh TK, et al. Rehabilitation of persons with traumatic brain injury Journal of the American Medical Association. 282: 974-983. DOI: 10.1001/jama.282.10.974  1
1999 Huh J, Saatman KE, Raghupathi R, Laurer HL, Helfaer MA, McIntosh TK. Dephosphorylated neurofilaments are vulnerable following focal traumatic brain injury in mice Critical Care Medicine. 27: A59.  1
1999 Kesavulu V, Keller J, Helfaer MA, McIntosh TK, Welsh F, Raghupathi R. Hypoxic hypoxemia increases mortality and morbidity with mild experimental traumatic brain injury Critical Care Medicine. 27: A63.  1
1998 Saatman KE, Graham DI, McIntosh TK. The neuronal cytoskeleton is at risk after mild and moderate brain injury. Journal of Neurotrauma. 15: 1047-58. PMID 9872461  1
1998 Morrison B, Saatman KE, Meaney DF, McIntosh TK. In vitro central nervous system models of mechanically induced trauma: a review. Journal of Neurotrauma. 15: 911-28. PMID 9840765  1
1998 Raghupathi R, McIntosh TK. Pharmacotherapy for traumatic brain injury: a review. Proceedings of the Western Pharmacology Society. 41: 241-6. PMID 9836300  1
1998 McIntosh TK, Juhler M, Wieloch T. Novel pharmacologic strategies in the treatment of experimental traumatic brain injury: 1998. Journal of Neurotrauma. 15: 731-69. PMID 9814632  1
1998 Raghupathi R, Fernandez SC, Murai H, Trusko SP, Scott RW, Nishioka WK, McIntosh TK. BCL-2 overexpression attenuates cortical cell loss after traumatic brain injury in transgenic mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 18: 1259-69. PMID 9809516 DOI: 10.1097/00004647-199811000-00013  1
1998 O'Dell DM, Raghupathi R, Crino PB, Morrison B, Eberwine JH, McIntosh TK. Amplification of mRNAs from single, fixed, TUNEL-positive cells. Biotechniques. 25: 566-8, 570. PMID 9793634  1
1998 McIntosh TK, Saatman KE, Raghupathi R, Graham DI, Smith DH, Lee VM, Trojanowski JQ. The Dorothy Russell Memorial Lecture. The molecular and cellular sequelae of experimental traumatic brain injury: pathogenetic mechanisms. Neuropathology and Applied Neurobiology. 24: 251-67. PMID 9775390 DOI: 10.1046/j.1365-2990.1998.00121.x  1
1998 Smith DH, Cecil KM, Meaney DF, Chen XH, McIntosh TK, Gennarelli TA, Lenkinski RE. Magnetic resonance spectroscopy of diffuse brain trauma in the pig. Journal of Neurotrauma. 15: 665-74. PMID 9753214  1
1998 Pierce JE, Smith DH, Trojanowski JQ, McIntosh TK. Enduring cognitive, neurobehavioral and histopathological changes persist for up to one year following severe experimental brain injury in rats. Neuroscience. 87: 359-69. PMID 9740398 DOI: 10.1016/S0306-4522(98)00142-0  1
1998 Smith DH, Nakamura M, McIntosh TK, Wang J, Rodríguez A, Chen XH, Raghupathi R, Saatman KE, Clemens J, Schmidt ML, Lee VM, Trojanowski JQ. Brain trauma induces massive hippocampal neuron death linked to a surge in beta-amyloid levels in mice overexpressing mutant amyloid precursor protein. The American Journal of Pathology. 153: 1005-10. PMID 9736050  1
1998 Raghupathi R, Grants I, Rosenberg LJ, McIntosh TK, Lucas JH. Increased jun immunoreactivity in an in vitro model of mammalian spinal neuron physical injury. Journal of Neurotrauma. 15: 555-61. PMID 9674558  1
1998 Conti AC, Raghupathi R, Trojanowski JQ, McIntosh TK. Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 5663-72. PMID 9671657  1
1998 Okiyama K, Smith DH, White WF, McIntosh TK. Effects of the NMDA antagonist CP-98,113 on regional cerebral edema and cardiovascular, cognitive, and neurobehavioral function following experimental brain injury in the rat. Brain Research. 792: 291-8. PMID 9593949 DOI: 10.1016/S0006-8993(98)00158-9  1
1998 Zhang C, Raghupathi R, Saatman KE, Smith DH, Stutzmann JM, Wahl F, McIntosh TK. Riluzole attenuates cortical lesion size, but not hippocampal neuronal loss, following traumatic brain injury in the rat. Journal of Neuroscience Research. 52: 342-9. PMID 9590442 DOI: 10.1002/(SICI)1097-4547(19980501)52:3<342::AID-JNR10>3.0.CO;2-8  1
1998 Cecil KM, Hills EC, Sandel ME, Smith DH, McIntosh TK, Mannon LJ, Sinson GP, Bagley LJ, Grossman RI, Lenkinski RE. Proton magnetic resonance spectroscopy for detection of axonal injury in the splenium of the corpus callosum of brain-injured patients. Journal of Neurosurgery. 88: 795-801. PMID 9576245 DOI: 10.3171/jns.1998.88.5.0795  1
1998 Cecil KM, Lenkinski RE, Meaney DF, McIntosh TK, Smith DH. High-field proton magnetic resonance spectroscopy of a swine model for axonal injury. Journal of Neurochemistry. 70: 2038-44. PMID 9572290  1
1998 Morrison B, Meaney DF, McIntosh TK. Mechanical characterization of an in vitro device designed to quantitatively injure living brain tissue. Annals of Biomedical Engineering. 26: 381-90. PMID 9570221  1
1998 Murai H, Pierce JE, Raghupathi R, Smith DH, Saatman KE, Trojanowski JQ, Lee VM, Loring JF, Eckman C, Younkin S, McIntosh TK. Twofold overexpression of human beta-amyloid precursor proteins in transgenic mice does not affect the neuromotor, cognitive, or neurodegenerative sequelae following experimental brain injury. The Journal of Comparative Neurology. 392: 428-38. PMID 9514508 DOI: 10.1002/(SICI)1096-9861(19980323)392:4<428::AID-CNE2>3.0.CO;2-2  1
1997 Bareyre F, Wahl F, McIntosh TK, Stutzmann JM. Time course of cerebral edema after traumatic brain injury in rats: effects of riluzole and mannitol. Journal of Neurotrauma. 14: 839-49. PMID 9421455  1
1997 Smith DH, Chen XH, Pierce JE, Wolf JA, Trojanowski JQ, Graham DI, McIntosh TK. Progressive atrophy and neuron death for one year following brain trauma in the rat. Journal of Neurotrauma. 14: 715-27. PMID 9383090  1
1997 Saatman KE, Contreras PC, Smith DH, Raghupathi R, McDermott KL, Fernandez SC, Sanderson KL, Voddi M, McIntosh TK. Insulin-like growth factor-1 (IGF-1) improves both neurological motor and cognitive outcome following experimental brain injury. Experimental Neurology. 147: 418-27. PMID 9344566 DOI: 10.1006/exnr.1997.6629  1
1997 Smith DH, Perri BR, Raghupathi R, Saatman KE, McIntosh TK. Remacemide hydrochloride reduces cortical lesion volume following brain trauma in the rat. Neuroscience Letters. 231: 135-8. PMID 9300640 DOI: 10.1016/S0304-3940(97)00551-X  1
1997 Rubin Y, Cecil K, Wehrli S, McIntosh TK, Lenkinski RE, Smith DH. High-resolution 1H NMR spectroscopy following experimental brain trauma. Journal of Neurotrauma. 14: 441-9. PMID 9257662  1
1997 McIntosh TK, Garde E, Saatman KE, Smith DH. Central nervous system resuscitation. Emergency Medicine Clinics of North America. 15: 527-50. PMID 9255131 DOI: 10.1016/S0733-8627(05)70316-3  1
1997 Smith DH, Chen XH, Xu BN, McIntosh TK, Gennarelli TA, Meaney DF. Characterization of diffuse axonal pathology and selective hippocampal damage following inertial brain trauma in the pig. Journal of Neuropathology and Experimental Neurology. 56: 822-34. PMID 9210879  1
1997 Okiyama K, Smith DH, White WF, Richter K, McIntosh TK. Effects of the novel NMDA antagonists CP-98,113, CP-101,581 and CP-101,606 on cognitive function and regional cerebral edema following experimental brain injury in the rat. Journal of Neurotrauma. 14: 211-22. PMID 9151770  1
1997 McDermott KL, Raghupathi R, Fernandez SC, Saatman KE, Protter AA, Finklestein SP, Sinson G, Smith DH, McIntosh TK. Delayed administration of basic fibroblast growth factor (bFGF) attenuates cognitive dysfunction following parasagittal fluid percussion brain injury in the rat. Journal of Neurotrauma. 14: 191-200. PMID 9151768  1
1997 Perri BR, Smith DH, Murai H, Sinson G, Saatman KE, Raghupathi R, Bartus RT, McIntosh TK. Metabolic quantification of lesion volume following experimental traumatic brain injury in the rat. Journal of Neurotrauma. 14: 15-22. PMID 9048307  1
1997 Sinson G, Perri BR, Trojanowski JQ, Flamm ES, McIntosh TK. Improvement of cognitive deficits and decreased cholinergic neuronal cell loss and apoptotic cell death following neurotrophin infusion after experimental traumatic brain injury. Journal of Neurosurgery. 86: 511-8. PMID 9046309 DOI: 10.3171/jns.1997.86.3.0511  1
1997 Vink R, Golding EM, Williams JP, McIntosh TK. Blood glucose concentration does not affect outcome in brain trauma: A 31P MRS study. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 17: 50-3. PMID 8978386 DOI: 10.1097/00004647-199701000-00007  1
1997 Raghupathi R, McIntosh TK. Drugs in the management of acute traumatic brain injury Physical Medicine and Rehabilitation Clinics of North America. 8: 629-649.  1
1997 Mcintosh TK, Saatman KE, Raghupathi R. Calcium and the pathogenesis of traumatic CNS injury: Cellular and molecular mechanisms Neuroscientist. 3: 169-175.  1
1996 Sinson G, Voddi M, Flamm ES, McIntosh TK. Neurotrophin infusion improves cognitive deficits and decreases cholinergic neuronal cell loss after experimental brain injury. Clinical Neurosurgery. 43: 219-27. PMID 9247806  1
1996 McIntosh TK, Smith DH, Voddi M, Perri BR, Stutzmann JM. Riluzole, a novel neuroprotective agent, attenuates both neurologic motor and cognitive dysfunction following experimental brain injury in the rat. Journal of Neurotrauma. 13: 767-80. PMID 9002062  1
1996 Fan L, Young PR, Barone FC, Feuerstein GZ, Smith DH, McIntosh TK. Experimental brain injury induces differential expression of tumor necrosis factor-alpha mRNA in the CNS. Brain Research. Molecular Brain Research. 36: 287-91. PMID 8965649 DOI: 10.1016/0169-328X(95)00274-V  1
1996 Saatman KE, Bozyczko-Coyne D, Marcy V, Siman R, McIntosh TK. Prolonged calpain-mediated spectrin breakdown occurs regionally following experimental brain injury in the rat. Journal of Neuropathology and Experimental Neurology. 55: 850-60. PMID 8965100  1
1996 Hill SJ, Barbarese E, McIntosh TK. Regional heterogeneity in the response of astrocytes following traumatic brain injury in the adult rat. Journal of Neuropathology and Experimental Neurology. 55: 1221-9. PMID 8957445  1
1996 Alsop DC, Murai H, Detre JA, McIntosh TK, Smith DH. Detection of acute pathologic changes following experimental traumatic brain injury using diffusion-weighted magnetic resonance imaging. Journal of Neurotrauma. 13: 515-21. PMID 8913968  1
1996 McIntosh TK, Smith DH, Meaney DF, Kotapka MJ, Gennarelli TA, Graham DI. Neuropathological sequelae of traumatic brain injury: relationship to neurochemical and biomechanical mechanisms. Laboratory Investigation; a Journal of Technical Methods and Pathology. 74: 315-42. PMID 8780153  1
1996 Loring JF, Paszty C, Rose A, McIntosh TK, Murai H, Pierce JE, Schramm SR, Wymore K, Lee VM, Trojanowski JQ, Peterson KR. Rational design of an animal model for Alzheimer's disease: introduction of multiple human genomic transgenes to reproduce AD pathology in a rodent. Neurobiology of Aging. 17: 173-82. PMID 8744398 DOI: 10.1016/0197-4580(95)02076-4  1
1996 Raghupathi R, McIntosh TK. Regionally and temporally distinct patterns of induction of c-fos, c-jun and junB mRNAs following experimental brain injury in the rat. Brain Research. Molecular Brain Research. 37: 134-44. PMID 8738144 DOI: 10.1016/0169-328X(95)00289-5  1
1996 McIntosh TK, Smith DH, Garde E. Therapeutic approaches for the prevention of secondary brain injury. European Journal of Anaesthesiology. 13: 291-309. PMID 8737120  1
1996 Kimura H, Meaney DF, McGowan JC, Grossman RI, Lenkinski RE, Ross DT, McIntosh TK, Gennarelli TA, Smith DH. Magnetization transfer imaging of diffuse axonal injury following experimental brain injury in the pig: characterization by magnetization transfer ratio with histopathologic correlation. Journal of Computer Assisted Tomography. 20: 540-6. PMID 8708052 DOI: 10.1097/00004728-199607000-00007  1
1996 Vink R, Heath DL, McIntosh TK. Acute and prolonged alterations in brain free magnesium following fluid percussion-induced brain trauma in rats. Journal of Neurochemistry. 66: 2477-83. PMID 8632172  1
1996 Saatman KE, Murai H, Bartus RT, Smith DH, Hayward NJ, Perri BR, McIntosh TK. Calpain inhibitor AK295 attenuates motor and cognitive deficits following experimental brain injury in the rat. Proceedings of the National Academy of Sciences of the United States of America. 93: 3428-33. PMID 8622952 DOI: 10.1073/pnas.93.8.3428  1
1996 Sinson G, Voddi M, McIntosh TK. Combined fetal neural transplantation and nerve growth factor infusion: effects on neurological outcome following fluid-percussion brain injury in the rat. Journal of Neurosurgery. 84: 655-62. PMID 8613859 DOI: 10.3171/jns.1996.84.4.0655  1
1996 Pierce JE, Trojanowski JQ, Graham DI, Smith DH, McIntosh TK. Immunohistochemical characterization of alterations in the distribution of amyloid precursor proteins and beta-amyloid peptide after experimental brain injury in the rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 1083-90. PMID 8558237  1
1995 Raghupathi R, McIntosh TK, Smith DH. Cellular responses to experimental brain injury. Brain Pathology (Zurich, Switzerland). 5: 437-42. PMID 8974626  1
1995 McIntosh TK, Raghupathi R. Cell stress genes and acute CNS injury. Neuropathology and Applied Neurobiology. 21: 477-9. PMID 8745233  1
1995 Soares HD, Sinson GP, McIntosh TK. Fetal hippocampal transplants attenuate CA3 pyramidal cell death resulting from fluid percussion brain injury in the rat. Journal of Neurotrauma. 12: 1059-67. PMID 8742134  1
1995 Smith DH, Meaney DF, Lenkinski RE, Alsop DC, Grossman R, Kimura H, McIntosh TK, Gennarelli TA. New magnetic resonance imaging techniques for the evaluation of traumatic brain injury. Journal of Neurotrauma. 12: 573-7. PMID 8683608  1
1995 Soares HD, Hicks RR, Smith D, McIntosh TK. Inflammatory leukocytic recruitment and diffuse neuronal degeneration are separate pathological processes resulting from traumatic brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 8223-33. PMID 8613756  1
1995 Hayes RL, Yang K, Raghupathi R, McIntosh TK. Changes in gene expression following traumatic brain injury in the rat. Journal of Neurotrauma. 12: 779-90. PMID 8594207  1
1995 Okiyama K, Smith DH, Gennarelli TA, Simon RP, Leach M, McIntosh TK. The sodium channel blocker and glutamate release inhibitor BW1003C87 and magnesium attenuate regional cerebral edema following experimental brain injury in the rat. Journal of Neurochemistry. 64: 802-9. PMID 7830074  1
1995 Yamakami I, Vink R, Faden AI, Gennarelli TA, Lenkinski R, McIntosh TK. Effects of acute ethanol intoxication on experimental brain injury in the rat: neurobehavioral and phosphorus-31 nuclear magnetic resonance spectroscopy studies. Journal of Neurosurgery. 82: 813-21. PMID 7714607 DOI: 10.3171/jns.1995.82.5.0813  1
1995 Raghupathi R, Welsh FA, Lowenstein DH, Gennarelli TA, McIntosh TK. Regional induction of c-fos and heat shock protein-72 mRNA following fluid-percussion brain injury in the rat. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 15: 467-73. PMID 7714005 DOI: 10.1038/jcbfm.1995.58  1
1995 Smith DH, Soares HD, Pierce JS, Perlman KG, Saatman KE, Meaney DF, Dixon CE, McIntosh TK. A model of parasagittal controlled cortical impact in the mouse: cognitive and histopathologic effects. Journal of Neurotrauma. 12: 169-78. PMID 7629863  1
1995 Hicks RR, Smith DH, McIntosh TK. Temporal response and effects of excitatory amino acid antagonism on microtubule-associated protein 2 immunoreactivity following experimental brain injury in rats. Brain Research. 678: 151-60. PMID 7620884 DOI: 10.1016/0006-8993(95)00179-T  1
1995 Fan L, Young PR, Barone FC, Feuerstein GZ, Smith DH, McIntosh TK. Experimental brain injury induces expression of interleukin-1 beta mRNA in the rat brain. Brain Research. Molecular Brain Research. 30: 125-30. PMID 7609633 DOI: 10.1016/0169-328X(94)00287-O  1
1995 Sinson G, Voddi M, McIntosh TK. Nerve growth factor administration attenuates cognitive but not neurobehavioral motor dysfunction or hippocampal cell loss following fluid-percussion brain injury in rats. Journal of Neurochemistry. 65: 2209-16. PMID 7595509  1
1995 Smith DH, Casey K, McIntosh TK. Pharmacologic therapy for traumatic brain injury: experimental approaches. New Horizons (Baltimore, Md.). 3: 562-72. PMID 7496768  1
1995 Rink A, Fung KM, Trojanowski JQ, Lee VM, Neugebauer E, McIntosh TK. Evidence of apoptotic cell death after experimental traumatic brain injury in the rat. The American Journal of Pathology. 147: 1575-83. PMID 7495282  1
1995 Smith DH, Gennarelli TA, McIntosh TK. The Potential of 21-Aminosteroids (Lazaroids) as Neuroprotective Therapies in CNS Injury Cns Drugs. 3: 159-164. DOI: 10.2165/00023210-199503030-00001  1
1995 McIntosh TK, Smith DH. Therapeutic strategies in current clinical trials Journal of Head Trauma Rehabilitation. 10: 1-6.  1
1994 Okiyama K, Rosenkrantz TS, Smith DH, Gennarelli TA, McIntosh TK. (S)-emopamil attenuates acute reduction in regional cerebral blood flow following experimental brain injury. Journal of Neurotrauma. 11: 83-95. PMID 8201628  1
1994 Prasad MR, Ramaiah C, McIntosh TK, Dempsey RJ, Hipkens S, Yurek D. Regional levels of lactate and norepinephrine after experimental brain injury. Journal of Neurochemistry. 63: 1086-94. PMID 8051549  1
1994 Smith DH, Lowenstein DH, Gennarelli TA, McIntosh TK. Persistent memory dysfunction is associated with bilateral hippocampal damage following experimental brain injury. Neuroscience Letters. 168: 151-4. PMID 8028769 DOI: 10.1016/0304-3940(94)90438-3  1
1994 Lowenstein DH, Gwinn RP, Seren MS, Simon RP, McIntosh TK. Increased expression of mRNA encoding calbindin-D28K, the glucose-regulated proteins, or the 72 kDa heat-shock protein in three models of acute CNS injury. Brain Research. Molecular Brain Research. 22: 299-308. PMID 8015387 DOI: 10.1016/0169-328X(94)90058-2  1
1994 McIntosh TK, Yu T, Gennarelli TA. Alterations in regional brain catecholamine concentrations after experimental brain injury in the rat. Journal of Neurochemistry. 63: 1426-33. PMID 7931293  0.76
1994 Povlishock JT, Hayes RL, Michel ME, McIntosh TK. Workshop on animal models of traumatic brain injury. Journal of Neurotrauma. 11: 723-32. PMID 7723071  1
1993 Tzigaret C, McIntosh TK, Okiyama K, Jenkins WL, Prasad MR. Measurement of hippocampal levels of cellular second messengers following in situ freezing. Journal of Neurochemistry. 60: 827-34. PMID 8436972  0.72
1993 Smith DH, Okiyama K, Thomas MJ, McIntosh TK. Effects of the excitatory amino acid receptor antagonists kynurenate and indole-2-carboxylic acid on behavioral and neurochemical outcome following experimental brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 5383-92. PMID 8254381  1
1993 Pierce JE, Smith DH, Eison MS, McIntosh TK. The nootropic compound BMY-21502 improves spatial learning ability in brain injured rats. Brain Research. 624: 199-208. PMID 8252392  1
1993 Smith DH, Okiyama K, Gennarelli TA, McIntosh TK. Magnesium and ketamine attenuate cognitive dysfunction following experimental brain injury. Neuroscience Letters. 157: 211-4. PMID 8233056  1
1993 Hicks RR, Smith DH, Lowenstein DH, Saint Marie R, McIntosh TK. Mild experimental brain injury in the rat induces cognitive deficits associated with regional neuronal loss in the hippocampus. Journal of Neurotrauma. 10: 405-14. PMID 8145264  1
1993 McIntosh TK, Fernyak S, Hayes RL, Faden AI. Beneficial effect of the nonselective opiate antagonist naloxone hydrochloride and the thyrotropin-releasing hormone (TRH) analog YM-14673 on long-term neurobehavioral outcome following experimental brain injury in the rat. Journal of Neurotrauma. 10: 373-84. PMID 8145261  1
1993 Fan L, Yeston NS, McIntosh TK. Effect of dynorphin microinjection in the anterior hypothalamus (AV3V) region on the hemodynamic response to hemorrhage in the rat. Circulatory Shock. 39: 147-52. PMID 8098273  0.68
1992 McIntosh TK, Thomas M, Smith D, Banbury M. The novel 21-aminosteroid U74006F attenuates cerebral edema and improves survival after brain injury in the rat. Journal of Neurotrauma. 9: 33-46. PMID 1619674  0.6
1992 Soares HD, Thomas M, Cloherty K, McIntosh TK. Development of prolonged focal cerebral edema and regional cation changes following experimental brain injury in the rat. Journal of Neurochemistry. 58: 1845-52. PMID 1560237  1
1992 Okiyama K, Smith DH, Thomas MJ, McIntosh TK. Evaluation of a novel calcium channel blocker, (S)-emopamil, on regional cerebral edema and neurobehavioral function after experimental brain injury. Journal of Neurosurgery. 77: 607-15. PMID 1527621 DOI: 10.3171/jns.1992.77.4.0607  1
1992 Lowenstein DH, Thomas MJ, Smith DH, McIntosh TK. Selective vulnerability of dentate hilar neurons following traumatic brain injury: a potential mechanistic link between head trauma and disorders of the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 4846-53. PMID 1464770  1
1992 Prasad MR, Tzigaret CM, Smith D, Soares H, McIntosh TK. Decreased alpha 1-adrenergic receptors after experimental brain injury. Journal of Neurotrauma. 9: 269-79. PMID 1335519  1
1991 Smith DH, Okiyama K, Thomas MJ, Claussen B, McIntosh TK. Evaluation of memory dysfunction following experimental brain injury using the Morris water maze. Journal of Neurotrauma. 8: 259-69. PMID 1803034  1
1991 Soares H, McIntosh TK. Fetal cortical transplants in adult rats subjected to experimental brain injury. Journal of Neural Transplantation & Plasticity. 2: 207-20. PMID 1782253 DOI: 10.1155/NP.1991.207  1
1990 Hayes RL, Lyeth BG, Jenkins LW, Zimmerman R, McIntosh TK, Clifton GL, Young HF. Possible protective effect of endogenous opioids in traumatic brain injury. Journal of Neurosurgery. 72: 252-61. PMID 2295922 DOI: 10.3171/jns.1990.72.2.0252  1
1990 McIntosh TK, Vink R, Soares H, Hayes R, Simon R. Effect of noncompetitive blockade of N-methyl-D-aspartate receptors on the neurochemical sequelae of experimental brain injury. Journal of Neurochemistry. 55: 1170-9. PMID 2168932  1
1990 McIntosh TK, Banbury M, Smith D, Thomas M. The novel 21-aminosteroid U-74006F attenuates cerebral oedema and improves survival after brain injury in the rat. Acta Neurochirurgica. Supplementum. 51: 329-30. PMID 2089929  0.6
1990 McIntosh TK, Soares H, Thomas M, Cloherty K. Development of regional cerebral oedema after lateral fluid-percussion brain injury in the rat. Acta Neurochirurgica. Supplementum. 51: 263-4. PMID 2089913  1
1989 McIntosh TK, Vink R, Noble L, Yamakami I, Fernyak S, Soares H, Faden AL. Traumatic brain injury in the rat: characterization of a lateral fluid-percussion model. Neuroscience. 28: 233-44. PMID 2761692 DOI: 10.1016/0306-4522(89)90247-9  1
1989 Mcintosh TK, Vink R, Soares H, Hayes R, Simon R. Effects of the N-methyl-D-aspartate receptor blocker MK-801 on neurologic function after experimental brain injury. Journal of Neurotrauma. 6: 247-59. PMID 2559212  1
1988 Andrews BT, McIntosh TK, Gonzales MF, Weinstein PR, Faden AI. Levels of endogenous opioids and effects of an opiate antagonist during regional cerebral ischemia in rats. The Journal of Pharmacology and Experimental Therapeutics. 247: 1248-54. PMID 3204516  1
1988 Ferriero DM, Arcavi LJ, Sagar SM, McIntosh TK, Simon RP. Selective sparing of NADPH-diaphorase neurons in neonatal hypoxia-ischemia. Annals of Neurology. 24: 670-6. PMID 2904792 DOI: 10.1002/ana.410240512  0.52
1988 Andrews BT, Levy M, McIntosh TK, Pitts LH. An epidural intracranial pressure monitor for experimental use in the rat. Neurological Research. 10: 123-6. PMID 2902527  1
1987 McIntosh TK, Hayes RL, DeWitt DS, Agura V, Faden AI. Endogenous opioids may mediate secondary damage after experimental brain injury. The American Journal of Physiology. 253: E565-74. PMID 2891303  0.32
1986 McIntosh TK, Palter M, Grasberger R, Vezina R, Gerstein L, Yeston N, Egdahl RH. Endorphins in primate hemorrhagic shock: beneficial action of opiate antagonists. The Journal of Surgical Research. 40: 265-75. PMID 2936929 DOI: 10.1016/0022-4804(86)90160-5  1
1985 McIntosh TK, Palter M, Grasberger R, Vezina R, Yeston NS, Egdahl RH. Effect of an opiate antagonist (naloxone) and an agonist/antagonist (nalbuphine) in primate hemorrhagic shock: relationship to catecholamine release. Circulatory Shock. 17: 313-25. PMID 4092345  0.68
1985 McIntosh TK, Bush HL, Palter M, Hay JR, Aun F, Yeston NS, Egdahl RH. Prolonged disruption of plasma beta-endorphin dynamics following surgery. The Journal of Surgical Research. 38: 210-5. PMID 3157023 DOI: 10.1016/0022-4804(85)90028-9  1
1985 McIntosh TK, Bush HL, Yeston NS, Grasberger R, Palter M, Aun F, Egdahl RH. Beta-endorphin, cortisol and postoperative delirium: a preliminary report. Psychoneuroendocrinology. 10: 303-13. PMID 2932761 DOI: 10.1016/0306-4530(85)90007-1  1
1984 McIntosh TK, Barfield RJ, Thomas D. Electrophysiological and ultrasonic correlates of reproductive behavior in the male rat. Behavioral Neuroscience. 98: 1100-3. PMID 6508914 DOI: 10.1037//0735-7044.98.6.1100  1
1984 Aun F, McIntosh TK, Lee A, Egdahl RH. The effects of surgery on the circadian rhythms of cortisol. International Surgery. 69: 101-5. PMID 6500872  1
1984 McIntosh TK, Barfield RJ. Brain monoaminergic control of male reproductive behavior. II. Dopamine and the post-ejaculatory refractory period. Behavioural Brain Research. 12: 267-73. PMID 6432003 DOI: 10.1016/0166-4328(84)90152-9  1
1984 McIntosh TK, Barfield RJ. Brain monoaminergic control of male reproductive behavior. I. Serotonin and the post-ejaculatory refractory period. Behavioural Brain Research. 12: 255-65. PMID 6235821 DOI: 10.1016/0166-4328(84)90151-7  1
1984 McIntosh TK, Barfield RJ. Brain monoaminergic control of male reproductive behavior. III. Norepinephrine and the post-ejaculatory refractory period. Behavioural Brain Research. 12: 275-81. PMID 6087842 DOI: 10.1016/0166-4328(84)90153-0  1
1983 Yeston NS, Grasberger RC, McIntosh TK. Naloxone in reversal of hypotension in septic shock. Jama. 250: 2287. PMID 6632126  0.68
1981 McIntosh TK, Lothrop DA, Lee A, Jackson BT, Nabseth D, Egdahl RH. Circadian rhythm of cortisol is altered in postsurgical patients. The Journal of Clinical Endocrinology and Metabolism. 53: 117-22. PMID 7240369 DOI: 10.1210/jcem-53-1-117  1
1980 Vallano ML, McIntosh TK. Morphine stimulates cholinergic neuronal activity in the rat hippocampus. Neuropharmacology. 19: 851-3. PMID 7422093 DOI: 10.1016/0028-3908(80)90082-9  1
1980 Thomas DA, McIntosh TK, Barfield RJ. Influence of androgen in the neonatal period on ejaculatory and postejaculatory behavior in the rat. Hormones and Behavior. 14: 153-62. PMID 7419168 DOI: 10.1016/0018-506X(80)90007-0  1
1980 Drickamer LC, McIntosh TK. Effects of adrenalectomy on the presence of a maturation-delaying pheromone in the urine of female mice. Hormones and Behavior. 14: 146-52. PMID 7419167 DOI: 10.1016/0018-506X(80)90006-9  1
1980 Levine RL, McIntosh TK, Lothrop DA, Jackson BT. Circadian periodicity of plasma corticosterone levels in rats subjected to hemorrhagic shock and surgical trauma. Hormone Research. 13: 385-95. PMID 7275000  0.32
1980 McIntosh TK, Vallano ML, Barfield RJ. Effects of morphine, beta-endorphin and naloxone on catecholamine levels and sexual behavior in the male rat. Pharmacology, Biochemistry, and Behavior. 13: 435-41. PMID 6252562  1
1980 McIntosh TK, Barfield RJ. The temporal patterning of 40-60 kHz ultrasonic vocalizations and copulation in the rat (Rattus norvegicus) Behavioral and Neural Biology. 29: 349-358.  1
1979 McIntosh TK, Davis PG, Barfield RJ. Urine marking and sexual behavior in the rat (Rattus norvegicus). Behavioral and Neural Biology. 26: 161-8. PMID 496777 DOI: 10.1016/S0163-1047(79)92531-7  1
1979 Barfield RJ, Auerbach P, Geyer LA, Mcintosh TK. Ultrasonic vocalizations in rat sexual behavior Integrative and Comparative Biology. 19: 469-480. DOI: 10.1093/icb/19.2.469  1
1978 McIntosh TK, Barfield RJ, Geyer LA. Ultrasonic vocalisations facilitate sexual behaviour of female rats. Nature. 272: 163-4. PMID 628443 DOI: 10.1038/272163a0  1
1978 Drickamer LC, McIntosh TK, Rose EA. Effects of ovariectomy on the presence of a maturation-delaying pheromone in the urine of female mice. Hormones and Behavior. 11: 131-7. PMID 570953 DOI: 10.1016/0018-506X(78)90064-8  1
1978 Geyer LA, Barfield RJ, McIntosh TK. Influence of gonadal hormones and sexual behavior on ultrasonic vocalization in rats: II. Treatment of males Journal of Comparative and Physiological Psychology. 92: 447-456. DOI: 10.1037/h0077487  1
1978 Geyer LA, McIntosh TK, Barfield RJ. Effects of ultrasonic vocalizations and male's urine on female rat readiness to mate Journal of Comparative and Physiological Psychology. 92: 457-462. DOI: 10.1037/h0077478  1
1977 McIntosh TK, Drickamer LC. Excreted urine, bladder urine, and the delay of sexual maturation in female house mice. Animal Behaviour. 25: 999-1004. PMID 564151 DOI: 10.1016/0003-3472(77)90051-3  1
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