Robert C. Speth - Publications

Affiliations: 
The University of Mississippi, USA 
Area:
Neuroscience Biology, Animal Physiology Biology, Pharmacology

179 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Noto NM, Restrepo YM, Pang HW, Stoyell-Conti F, West CA, Speth RC. Comparative evaluation of biased agonists Sarcosine , d-Alanine -Angiotensin (Ang) II (SD Ang II) and Sarcosine , Isoleucine -Ang II (SI Ang II) and their radioiodinated congeners binding to rat liver membrane AT receptors. Pharmacology Research & Perspectives. 11: e01053. PMID 36639940 DOI: 10.1002/prp2.1053  0.41
2022 Speth RC, Bader M. Why Angiotensin II is a Poor Choice for Circulatory Support of Ventilated COVID-19 Patients Compared to Vasopressin. Medical Research Archives. 10. PMID 36438606  0.417
2021 Noto NM, Restrepo YM, Speth RC. Countering the classical renin-angiotensin system. Clinical Science (London, England : 1979). 135: 2619-2623. PMID 34878506 DOI: 10.1042/CS20211043  0.369
2021 Mehranfard D, Linares A, Chabbra A, Campos G, de Souza AMA, Ji H, West C, Sandberg K, Speth RC. Preliminary study of ovariectomy and chronic losartan-induced alterations in brain AT receptors. Brain Research. 1766: 147520. PMID 33991491 DOI: 10.1016/j.brainres.2021.147520  0.308
2021 Stoyell-Conti FF, Chabbra A, Puthentharayil J, Rigatto K, Speth RC. Chronic administration of pharmacological doses of angiotensin 1-7 and iodoangiotensin 1-7 has minimal effects on blood pressure, heart rate, and cognitive function of spontaneously hypertensive rats. Physiological Reports. 9: e14812. PMID 33904655 DOI: 10.14814/phy2.14812  0.365
2021 Kadam PS, Mueller SC, Ji H, Liu J, Pai AV, Ma J, Speth RC, Sandberg K. Modulation of the rat angiotensin type 1a receptor by an upstream short open reading frame. Peptides. 170529. PMID 33744369 DOI: 10.1016/j.peptides.2021.170529  0.351
2021 Stoyell-Conti FF, Itty S, Abraham C, Rigatto K, West CA, Speth RC. I-Angiotensin 1-7 binds to a different site than angiotensin 1-7 in tissue membrane preparations. Endocrine. PMID 33415576 DOI: 10.1007/s12020-020-02572-2  0.378
2021 Polak Y, Speth RC. Metabolism of angiotensin peptides by angiotensin converting enzyme 2 (ACE2) and analysis of the effect of excess zinc on ACE2 enzymatic activity. Peptides. 137: 170477. PMID 33400951 DOI: 10.1016/j.peptides.2020.170477  0.361
2020 Vadhan JD, Speth RC. The role of the brain renin-angiotensin system (RAS) in mild traumatic brain injury (TBI). Pharmacology & Therapeutics. 107684. PMID 32956721 DOI: 10.1016/J.Pharmthera.2020.107684  0.405
2020 Jha S, Speth RC, Macheroux P. The possible role of a bacterial aspartate β-decarboxylase in the biosynthesis of alamandine. Medical Hypotheses. 144: 110038. PMID 32758880 DOI: 10.1016/J.Mehy.2020.110038  0.44
2020 Ji H, de Souza AMA, Bajaj B, Zheng W, Wu X, Speth RC, Sandberg K. Sex-Specific Modulation of Blood Pressure and the Renin-Angiotensin System by ACE (Angiotensin-Converting Enzyme) 2. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA12015. PMID 32564694 DOI: 10.1161/Hypertensionaha.120.15276  0.427
2020 Speth RC. Angiotensin II administration to COVID-19 patients is not advisable. Critical Care (London, England). 24: 296. PMID 32503621 DOI: 10.1186/S13054-020-03032-Z  0.417
2020 Speth RC. Response to recent commentaries regarding the involvement of angiotensin-converting enzyme 2 (ACE2) and renin-angiotensin system blockers in SARS-CoV-2 infections. Drug Development Research. PMID 32304146 DOI: 10.1002/Ddr.21672  0.353
2020 De Souza AMA, Linares A, Speth RC, Campos GV, Ji H, Chianca D, Sandberg K, De Menezes RCA. Severe food restriction activates the central renin angiotensin system. Physiological Reports. 8: e14338. PMID 31925945 DOI: 10.14814/Phy2.14338  0.43
2020 Speth RC, Desai N, Chabbra A, Gnozzo G, Stoyell-Conti FF, West CA. 125‐I‐Sarcosine(1), D‐Alanine(8) Angiotensin II as a Biased Radioligand for AT1 Angiotensin II Receptors The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07177  0.517
2020 Stoyell-Conti FF, Chabbra A, Perry R, Speth RC. Pyridoxal 5 Phosphate Decarboxylates Angiotensin II: Putative Mechanism for Generation of Angiotensin A The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07034  0.448
2019 Koerperich ZM, Ericson MD, Freeman KT, Speth R, Pogozheva ID, Mosberg HI, Haskell-Luevano C. Incorporation of Agouti-Related Protein (AgRP) Human Single Nucleotide Polymorphisms (SNPs) in the AGRP-Derived Macrocyclic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-DPro] Decreases Melanocortin-4 Receptor Antagonist Potency and Results in the Discovery of Melanocortin-5 Receptor Antagonists. Journal of Medicinal Chemistry. PMID 31845801 DOI: 10.1021/Acs.Jmedchem.9B00860  0.351
2019 Yu Z, Swiercz AP, Moshfegh CM, Hopkins L, Wiaderkiewicz J, Speth RC, Park J, Marvar PJ. Angiotensin II Type 2 Receptor-Expressing Neurons in the Central Amygdala Influence Fear-Related Behavior. Biological Psychiatry. PMID 31420088 DOI: 10.1016/J.Biopsych.2019.05.027  0.444
2019 Pang HW, Linares A, Couling L, Santollo J, Ancheta L, Daniels D, Speth RC. Novel high molecular weight albumin-conjugated angiotensin II activates β-arrestin and G-protein pathways. Endocrine. PMID 31020463 DOI: 10.1007/S12020-019-01930-Z  0.452
2019 Parrish JN, Bertholomey ML, Pang HW, Speth RC, Torregrossa MM. Estradiol modulation of the renin-angiotensin system and the regulation of fear extinction. Translational Psychiatry. 9: 36. PMID 30696810 DOI: 10.1038/S41398-019-0374-0  0.439
2019 Stoyell-conti FF, Itty S, Asif M, Stewart H, Abraham C, West C, Speth RC. Abstract P2027: Preliminary Characterization Of The 125 I-angiotensin 1-7 Binding Site In Rat Liver Hypertension. 74. DOI: 10.1161/Hyp.74.Suppl_1.P2027  0.519
2018 Lensing CJ, Freeman KT, Schnell SM, Speth RC, Zarth AT, Haskell-Luevano C. Developing a Biased Unmatched Bivalent Ligand (BUmBL) Design Strategy to Target the GPCR Homodimer Allosteric Signaling (cAMP over β-Arrestin2 Recruitment) Within the Melanocortin Receptors. Journal of Medicinal Chemistry. PMID 29669202 DOI: 10.1021/Acs.Jmedchem.8B00238  0.381
2018 Ericson MD, Singh A, Tala SR, Haslach EM, Dirain MLS, Schaub JW, Flores V, Eick N, Lensing CJ, Freeman KT, Smeester BA, Adank DN, Wilber SL, Speth R, Haskell-Luevano C. Human β-Defensin-1 and β-Defensin-3 (Mouse Ortholog mBD14) Function as Full Endogenous Agonists at Select Melanocortin Receptors. Journal of Medicinal Chemistry. PMID 29578343 DOI: 10.1021/Acs.Jmedchem.8B00251  0.315
2018 Morgan BJ, Schrimpf N, Rothman M, Mitzey A, Brownfield MS, Speth RC, Dopp JM. Effect of Chronic Intermittent Hypoxia on Angiotensin II Receptors in the Central Nervous System. Clinical and Experimental Hypertension (New York, N.Y. : 1993). 1-7. PMID 29561178 DOI: 10.1080/10641963.2018.1451536  0.513
2017 Gonsai NH, Amin VH, Mendpara CG, Speth R, Hale GM. Effects of dopamine receptor antagonist antipsychotic therapy on blood pressure. Journal of Clinical Pharmacy and Therapeutics. PMID 29119585 DOI: 10.1111/Jcpt.12649  0.403
2017 PrabhuDas MR, Baldwin CL, Bollyky PL, Bowdish DME, Drickamer K, Febbraio M, Herz J, Kobzik L, Krieger M, Loike J, McVicker B, Means TK, Moestrup SK, Post SR, Sawamura T, ... ... Speth RC, et al. A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease. Journal of Immunology (Baltimore, Md. : 1950). 198: 3775-3789. PMID 28483986 DOI: 10.4049/Jimmunol.1700373  0.39
2017 Doering SR, Freeman KT, Schnell SM, Haslach EM, Dirain MLS, Ginamarie Debevec G, Geer P, Santos RG, Giulianotti MA, Pinilla C, Appel JR, Speth RC, Houghten RA, Haskell-Luevano C. Discovery of Mixed Pharmacology Melanocortin-3 Agonists and Melanocortin-4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa(1)-Arg-(pI)DPhe-Xaa((4))-NH2. Journal of Medicinal Chemistry. PMID 28453292 DOI: 10.1021/Acs.Jmedchem.7B00301  0.397
2017 Ji H, Pai AV, West CA, Wu X, Speth RC, Sandberg K. Loss of Resistance to Angiotensin II-Induced Hypertension in the Jackson Laboratory Recombination-Activating Gene Null Mouse on the C57BL/6J Background. Hypertension (Dallas, Tex. : 1979). PMID 28438904 DOI: 10.1161/Hypertensionaha.117.09063  0.444
2017 Lensing CJ, Adank DN, Wilber SL, Freeman KT, Schnell SM, Speth RC, Zarth AT, Haskell-Luevano C. A Direct In Vivo Comparison of The Melanocortin Monovalent Agonist Ac-His-DPhe-Arg-Trp-NH2 versus The Bivalent Agonist Ac-His-DPhe-Arg-Trp-PEDG20-His-DPhe-Arg-Trp-NH2: A Bivalent Advantage. Acs Chemical Neuroscience. PMID 28128928 DOI: 10.1021/Acschemneuro.6B00399  0.343
2016 Goldstein B, Speth RC, Trivedi M. Renin-angiotensin system gene expression and neurodegenerative diseases. Journal of the Renin-Angiotensin-Aldosterone System : Jraas. 17. PMID 27613758 DOI: 10.1177/1470320316666750  0.308
2016 Linares A, Couling LE, Carrera EJ, Speth RC. Receptor Autoradiography Protocol for the Localized Visualization of Angiotensin II Receptors. Journal of Visualized Experiments : Jove. PMID 27341008 DOI: 10.3791/53866  0.517
2016 Santollo J, Marshall A, Curtis KS, Speth RC, Clark SD, Daniels D. Divergent effects of ERα and ERβ on fluid intake by female rats are not dependent on concomitant changes in AT1R expression or body weight. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00102.2016. PMID 27122368 DOI: 10.1152/Ajpregu.00102.2016  0.425
2015 Ji H, Zheng W, Wu X, Speth RC, Verbalis JG, Stein LM, Yosten GL, Samson WK, Sandberg K. Aging-related impairment of urine concentrating mechanisms correlates with dysregulation of adrenocortical angiotensin type 1 receptors in male Fischer rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00131.2015. PMID 26702152 DOI: 10.1152/Ajpregu.00131.2015  0.36
2015 Yosten GL, Liu J, Ji H, Sandberg K, Speth R, Samson WK. A 5'-Upstream short open reading frame encoded peptide regulates angiotensin type 1a receptor production and signaling via the beta-arrestin pathway. The Journal of Physiology. PMID 26333095 DOI: 10.1113/Jp270567  0.413
2015 Hurt RC, Garrett JC, Keifer OP, Linares A, Couling L, Speth RC, Ressler KJ, Marvar PJ. Angiotensin type 1a receptors on corticotropin-releasing factor neurons contribute to the expression of conditioned fear(1). Genes, Brain, and Behavior. 14: 526-33. PMID 26257395 DOI: 10.1111/Gbb.12235  0.321
2015 Bourassa EA, Stedenfeld KA, Sved AF, Speth RC. Selective C1 Lesioning Slightly Decreases Angiotensin II Type I Receptor Expression in the Rat Rostral Ventrolateral Medulla (RVLM). Neurochemical Research. 40: 2113-20. PMID 26138553 DOI: 10.1007/S11064-015-1649-3  0.799
2015 Li W, Sullivan MN, Zhang S, Worker CJ, Xiong Z, Speth RC, Feng Y. Intracerebroventricular infusion of the (Pro)renin receptor antagonist PRO20 attenuates deoxycorticosterone acetate-salt-induced hypertension. Hypertension. 65: 352-61. PMID 25421983 DOI: 10.1161/Hypertensionaha.114.04458  0.49
2015 Bourassa EA, Stedenfeld KA, Sved AF, Speth RC. Selective C1 Lesioning Slightly Decreases Angiotensin II Type I Receptor Expression in the Rat Rostral Ventrolateral Medulla (RVLM) Neurochemical Research. DOI: 10.1007/s11064-015-1649-3  0.795
2014 Santollo J, Whalen PE, Speth RC, Clark SD, Daniels D. Properly timed exposure to central ANG II prevents behavioral sensitization and changes in angiotensin receptor expression. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 307: R1396-404. PMID 25354729 DOI: 10.1152/Ajpregu.00373.2014  0.507
2014 Speth RC, Carrera EJ, Bretón C, Linares A, Gonzalez-Reiley L, Swindle JD, Santos KL, Schadock I, Bader M, Karamyan VT. Distribution of non-AT1, non-AT2 binding of 125I-sarcosine1, isoleucine8 angiotensin II in neurolysin knockout mouse brains. Plos One. 9: e105762. PMID 25147932 DOI: 10.1371/Journal.Pone.0105762  0.496
2014 Speth RC, Vento PJ, Carrera EJ, Gonzalez-Reily L, Linares A, Santos K, Swindle JD, Daniels D. Acute repeated intracerebroventricular injections of angiotensin II reduce agonist and antagonist radioligand binding in the paraventricular nucleus of the hypothalamus and median preoptic nucleus in the rat brain. Brain Research. 1583: 132-40. PMID 25108041 DOI: 10.1016/J.Brainres.2014.07.053  0.527
2014 Tirupula KC, Desnoyer R, Speth RC, Karnik SS. Atypical signaling and functional desensitization response of MAS receptor to peptide ligands. Plos One. 9: e103520. PMID 25068582 DOI: 10.1371/Journal.Pone.0103520  0.327
2014 Blanch GT, Freiria-Oliveira AH, Speretta GF, Carrera EJ, Li H, Speth RC, Colombari E, Sumners C, Colombari DS. Increased expression of angiotensin II type 2 receptors in the solitary-vagal complex blunts renovascular hypertension. Hypertension. 64: 777-83. PMID 24958505 DOI: 10.1161/Hypertensionaha.114.03188  0.547
2014 Ji H, Zheng W, Li X, Liu J, Wu X, Zhang MA, Umans JG, Hay M, Speth RC, Dunn SE, Sandberg K. Sex-specific T-cell regulation of angiotensin II-dependent hypertension. Hypertension. 64: 573-82. PMID 24935938 DOI: 10.1161/Hypertensionaha.114.03663  0.303
2014 Liu J, Yosten GL, Ji H, Zhang D, Zheng W, Speth RC, Samson WK, Sandberg K. Selective inhibition of angiotensin receptor signaling through Erk1/2 pathway by a novel peptide. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 306: R619-26. PMID 24523339 DOI: 10.1152/Ajpregu.00562.2013  0.373
2014 Linares A, Carrera E, Speth R. Inhibition of angiotensin-converting enzyme-2 (ACE-2) activity and radioligand binding of a putative ACE-2 inhibitor (1067.5) The Faseb Journal. 28. DOI: 10.1096/Fasebj.28.1_Supplement.1067.5  0.345
2014 Speth R, Carrera E, Jean-Baptiste M, Joachim A, Linares A. Concentration-dependent effects of zinc on angiotensin-converting enzyme-2 activity (1067.4) The Faseb Journal. 28. DOI: 10.1096/Fasebj.28.1_Supplement.1067.4  0.437
2013 de Gasparo M, Speth RC, Baltatu OC, Vanderheyden P. Brain RAS: Hypertension and Beyond. International Journal of Hypertension. 2013: 157180. PMID 23589770 DOI: 10.1155/2013/157180  0.342
2013 Premer C, Lamondin C, Mitzey A, Speth RC, Brownfield MS. Immunohistochemical Localization of AT1a, AT1b, and AT2 Angiotensin II Receptor Subtypes in the Rat Adrenal, Pituitary, and Brain with a Perspective Commentary. International Journal of Hypertension. 2013: 175428. PMID 23573410 DOI: 10.1155/2013/175428  0.544
2013 Zhang Y, Gao Y, Speth RC, Jiang N, Mao Y, Sumners C, Li H. Adenoviral and adeno-associated viral vectors-mediated neuronal gene transfer to cardiovascular control regions of the rat brain. International Journal of Medical Sciences. 10: 607-16. PMID 23569423 DOI: 10.7150/Ijms.5700  0.368
2013 Santos KL, Vento MA, Wright JW, Speth RC. The effects of para-chloromercuribenzoic acid and different oxidative and sulfhydryl agents on a novel, non-AT1, non-AT2 angiotensin binding site identified as neurolysin Regulatory Peptides. 184: 104-114. PMID 23511333 DOI: 10.1016/J.Regpep.2013.03.021  0.464
2013 Chhabra KH, Xia H, Pedersen KB, Speth RC, Lazartigues E. Pancreatic angiotensin-converting enzyme 2 improves glycemia in angiotensin II-infused mice. American Journal of Physiology. Endocrinology and Metabolism. 304: E874-84. PMID 23462816 DOI: 10.1152/Ajpendo.00490.2012  0.435
2013 Swindle JD, Santos KL, Speth RC. Pharmacological characterization of a novel non-AT1, non-AT2 angiotensin binding site identified as neurolysin. Endocrine. 44: 525-31. PMID 23412923 DOI: 10.1007/S12020-013-9898-X  0.502
2013 Nistala R, Andresen BT, Pulakat L, Meuth A, Sinak C, Mandavia C, Thekkumkara T, Speth RC, Whaley-Connell A, Sowers JR. Angiotensin type 1 receptor resistance to blockade in the opossum proximal tubule cell due to variations in the binding pocket. American Journal of Physiology. Renal Physiology. 304: F1105-13. PMID 23389452 DOI: 10.1152/Ajprenal.00127.2012  0.501
2012 Gonzalez AD, Wang G, Waters EM, Gonzales KL, Speth RC, Van Kempen TA, Marques-Lopes J, Young CN, Butler SD, Davisson RL, Iadecola C, Pickel VM, Pierce JP, Milner TA. Distribution of angiotensin type 1a receptor-containing cells in the brains of bacterial artificial chromosome transgenic mice. Neuroscience. 226: 489-509. PMID 22922351 DOI: 10.1016/J.Neuroscience.2012.08.039  0.376
2012 Wangler NJ, Santos KL, Schadock I, Hagen FK, Escher E, Bader M, Speth RC, Karamyan VT. Identification of membrane-bound variant of metalloendopeptidase neurolysin (EC 3.4.24.16) as the non-angiotensin type 1 (non-AT1), non-AT2 angiotensin binding site. The Journal of Biological Chemistry. 287: 114-22. PMID 22039052 DOI: 10.1074/Jbc.M111.273052  0.414
2012 Speth RC, Harding JW. Radiolabeling of Angiotensin peptides. Methods in Molecular Medicine. 51: 275-95. PMID 21331724 DOI: 10.1385/1-59259-087-X:275  0.388
2012 Lu X, Grove KL, Zhang W, Speth RC. Pharmacological characterization of angiotensin II AT(2) receptor subtype heterogeneity in the rat adrenal cortex and medulla. Endocrine. 3: 255-61. PMID 21153171 DOI: 10.1007/Bf03021402  0.389
2012 Tamura CS, Speth RC. Effects of angiotensin II on phosphatidylinositide hydrolysis in rat brain. Neurochemistry International. 17: 475-9. PMID 20504648 DOI: 10.1016/0197-0186(90)90030-W  0.496
2010 Karamyan VT, Arsenault J, Escher E, Speth RC. Preliminary biochemical characterization of the novel, non-AT1, non-AT2 angiotensin binding site from the rat brain. Endocrine. 37: 442-8. PMID 20960166 DOI: 10.1007/S12020-010-9328-2  0.473
2010 Bourassa EA, Fang X, Li X, Sved AF, Speth RC. AT₁ angiotensin II receptor and novel non-AT₁, non-ATâ‚‚ angiotensin II/III binding site in brainstem cardiovascular regulatory centers of the spontaneously hypertensive rat. Brain Research. 1359: 98-106. PMID 20807518 DOI: 10.1016/J.Brainres.2010.08.081  0.814
2010 Rabey FM, Karamyan VT, Speth RC. Distribution of a novel binding site for angiotensins II and III in mouse tissues. Regulatory Peptides. 162: 5-11. PMID 20171994 DOI: 10.1016/J.Regpep.2010.02.007  0.454
2010 Müller D, Greenland KJ, Speth RC, Middendorff R. Neuronal differentiation of NG108-15 cells has impact on nitric oxide- and membrane (natriuretic peptide receptor-A) cyclic GMP-generating proteins. Molecular and Cellular Endocrinology. 320: 118-27. PMID 20097258 DOI: 10.1016/J.Mce.2010.01.022  0.312
2010 Mizuno CS, Chittiboyina AG, Shah FH, Patny A, Kurtz TW, Pershadsingh HA, Speth RC, Karamyan VT, Carvalho PB, Avery MA. Design, synthesis, and docking studies of novel benzimidazoles for the treatment of metabolic syndrome. Journal of Medicinal Chemistry. 53: 1076-85. PMID 20073471 DOI: 10.1021/Jm901272D  0.411
2010 Bourassa EA, Speth RC. Water deprivation increases angiotensin-converting enzyme but not AT(1) receptor expression in brainstem and paraventricular nucleus of the hypothalamus of the rat. Brain Research. 1319: 83-91. PMID 20051229 DOI: 10.1016/J.Brainres.2009.12.079  0.803
2010 Feng Y, Xia H, Cai Y, Halabi CM, Becker LK, Santos RA, Speth RC, Sigmund CD, Lazartigues E. Brain-selective overexpression of human Angiotensin-converting enzyme type 2 attenuates neurogenic hypertension. Circulation Research. 106: 373-82. PMID 19926873 DOI: 10.1161/Circresaha.109.208645  0.416
2010 Feng Y, Xia H, Santos RA, Speth R, Lazartigues E. Angiotensin-converting enzyme 2: A new target for neurogenic hypertension Experimental Physiology. 95: 601-606. PMID 19923158 DOI: 10.1113/Expphysiol.2009.047407  0.51
2010 Bourassa EA, Sved AF, Speth RC. Anteroposterior distribution of AT(1) angiotensin receptors in caudal brainstem cardiovascular regulatory centers of the rat. Brain Research. 1306: 69-76. PMID 19835848 DOI: 10.1016/J.Brainres.2009.09.116  0.809
2010 Karamyan VT, Arsenault J, Escher E, Speth RC. Erratum to: Preliminary biochemical characterization of the novel, non-AT1, non-AT2 angiotensin binding site from the rat brain Endocrine. 38: 312-312. DOI: 10.1007/s12020-010-9347-z  0.317
2009 Müller D, Hida B, Guidone G, Speth RC, Michurina TV, Enikolopov G, Middendorff R. Expression of guanylyl cyclase (GC)-A and GC-B during brain development: evidence for a role of GC-B in perinatal neurogenesis. Endocrinology. 150: 5520-9. PMID 19837875 DOI: 10.1210/En.2009-0490  0.305
2009 Karamyan VT, Gadepalli R, Rimoldi JM, Speth RC. Brain AT1 angiotensin receptor subtype binding: importance of peptidase inhibition for identification of angiotensin II as its endogenous ligand. The Journal of Pharmacology and Experimental Therapeutics. 331: 170-7. PMID 19587313 DOI: 10.1124/Jpet.109.157461  0.533
2009 Pierce JP, Kievits J, Graustein B, Speth RC, Iadecola C, Milner TA. Sex differences in the subcellular distribution of angiotensin type 1 receptors and NADPH oxidase subunits in the dendrites of C1 neurons in the rat rostral ventrolateral medulla. Neuroscience. 163: 329-38. PMID 19501631 DOI: 10.1016/J.Neuroscience.2009.06.006  0.424
2009 Bourassa EA, Sved AF, Speth RC. Angiotensin modulation of rostral ventrolateral medulla (RVLM) in cardiovascular regulation. Molecular and Cellular Endocrinology. 302: 167-75. PMID 19027823 DOI: 10.1016/J.Mce.2008.10.039  0.749
2009 Mizuno CS, Chittiboyina AG, Patny A, Kurtz TW, Pershadsingh HA, Speth RC, Karamyan VT, Avery MA. Design, synthesis, and docking studies of telmisartan analogs for the treatment of metabolic syndrome Medicinal Chemistry Research. 18: 611-628. DOI: 10.1007/S00044-008-9153-9  0.397
2009 Chittiboyina AG, Mizuno CS, Desai PV, Patny A, Kurtz TW, Pershadsingh HA, Speth RC, Karamyan V, Avery MA. Design, synthesis, and docking studies of novel telmisartan-glitazone hybrid analogs for the treatment of metabolic syndrome Medicinal Chemistry Research. 18: 589-610. DOI: 10.1007/S00044-008-9152-X  0.39
2008 Karamyan VT, Stockmeier CA, Speth RC. Human brain contains a novel non-AT1, non-AT2 binding site for active angiotensin peptides. Life Sciences. 83: 421-5. PMID 18692076 DOI: 10.1016/J.Lfs.2008.07.003  0.37
2008 Wang G, Milner TA, Speth RC, Gore AC, Wu D, Iadecola C, Pierce JP. Sex differences in angiotensin signaling in bulbospinal neurons in the rat rostral ventrolateral medulla. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R1149-57. PMID 18685065 DOI: 10.1152/Ajpregu.90485.2008  0.443
2008 Karamyan VT, Gembardt F, Rabey FM, Walther T, Speth RC. Characterization of the brain-specific non-AT(1), non-AT(2) angiotensin binding site in the mouse. European Journal of Pharmacology. 590: 87-92. PMID 18571643 DOI: 10.1016/J.Ejphar.2008.05.035  0.525
2008 Karamyan VT, Speth RC. Distribution of the non-AT1, non-AT2 angiotensin-binding site in the rat brain: preliminary characterization. Neuroendocrinology. 88: 256-65. PMID 18562784 DOI: 10.1159/000140635  0.482
2008 Speth RC, Karamyan VT. The significance of brain aminopeptidases in the regulation of the actions of angiotensin peptides in the brain. Heart Failure Reviews. 13: 299-309. PMID 18188697 DOI: 10.1007/S10741-007-9078-2  0.487
2008 Speth RC, Karamyan VT. Brain angiotensin receptors and binding proteins. Naunyn-Schmiedeberg's Archives of Pharmacology. 377: 283-93. PMID 18172611 DOI: 10.1007/S00210-007-0238-7  0.503
2007 Grigore D, Ojeda NB, Robertson EB, Dawson AS, Huffman CA, Bourassa EA, Speth RC, Brosnihan KB, Alexander BT. Placental insufficiency results in temporal alterations in the renin angiotensin system in male hypertensive growth restricted offspring. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 293: R804-11. PMID 17537837 DOI: 10.1152/Ajpregu.00725.2006  0.768
2007 Karamyan VT, Speth RC. Enzymatic pathways of the brain renin-angiotensin system: unsolved problems and continuing challenges. Regulatory Peptides. 143: 15-27. PMID 17493693 DOI: 10.1016/J.Regpep.2007.03.006  0.478
2007 Kokje RJ, Wilson WL, Brown TE, Karamyan VT, Wright JW, Speth RC. Central pressor actions of aminopeptidase-resistant angiotensin II analogs: Challenging the angiotensin III hypothesis Hypertension. 49: 1328-1335. PMID 17470719 DOI: 10.1161/Hypertensionaha.107.087130  0.464
2007 Karamyan VT, Speth RC. Identification of a novel non-AT1, non-AT2 angiotensin binding site in the rat brain. Brain Research. 1143: 83-91. PMID 17306233 DOI: 10.1016/J.Brainres.2007.01.051  0.517
2007 Grobe JL, Mecca AP, Lingis M, Shenoy V, Bolton TA, Machado JM, Speth RC, Raizada MK, Katovich MJ. Prevention of angiotensin II-induced cardiac remodeling by angiotensin-(1-7). American Journal of Physiology. Heart and Circulatory Physiology. 292: H736-42. PMID 17098828 DOI: 10.1152/Ajpheart.00937.2006  0.51
2007 Karamyan VT, Speth RC. Identification of a novel, brain‐specific, non‐AT1, non‐AT2 binding site for angiotensins in the mouse brain The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A432-C  0.368
2007 Karamyan VT, Gadepalli RS, Rimoldi JM, Speth RC. Preservation of 125‐I‐Angiotensin II in brain AT‐1 receptor binding assays The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A432-B  0.499
2006 Müller D, Cortes-Dericks L, Budnik LT, Brunswig-Spickenheier B, Pancratius M, Speth RC, Mukhopadhyay AK, Middendorff R. Homologous and lysophosphatidic acid-induced desensitization of the atrial natriuretic peptide receptor, guanylyl cyclase-A, in MA-10 leydig cells. Endocrinology. 147: 2974-85. PMID 16527839 DOI: 10.1210/En.2006-0092  0.348
2006 ELAlfy A, Tan J, Wang H, Speth R, Leenen F. A117. Mineralocorticoid receptor densities increase in the brain, heart and kidneys after myocardial infarct in rats Journal of Molecular and Cellular Cardiology. 40: 908. DOI: 10.1016/J.Yjmcc.2006.03.408  0.377
2005 Wilson WL, Roques BP, Llorens-Cortes C, Speth RC, Harding JW, Wright JW. Roles of brain angiotensins II and III in thirst and sodium appetite. Brain Research. 1060: 108-17. PMID 16182260 DOI: 10.1016/J.Brainres.2005.08.032  0.408
2005 Speth RC, Kim KH, Elton TS, Simasko S. Sarcosine1, glycine8 angiotensin II is a functional AT1 angiotensin receptor antagonist. Endocrine. 26: 83-7. PMID 15888919 DOI: 10.1385/Endo:26:2:083  0.435
2005 Bugarith K, Dinh TT, Li AJ, Speth RC, Ritter S. Basomedial hypothalamic injections of neuropeptide Y conjugated to saporin selectively disrupt hypothalamic controls of food intake. Endocrinology. 146: 1179-91. PMID 15604214 DOI: 10.1210/En.2004-1166  0.342
2005 Glass MJ, Huang J, Speth RC, Iadecola C, Pickel VM. Angiotensin II AT-1A receptor immunolabeling in rat medial nucleus tractus solitarius neurons: subcellular targeting and relationships with catecholamines. Neuroscience. 130: 713-23. PMID 15590154 DOI: 10.1016/J.Neuroscience.2004.08.057  0.401
2004 Falcón BL, Stewart JM, Bourassa E, Katovich MJ, Walter G, Speth RC, Sumners C, Raizada MK. Angiotensin II type 2 receptor gene transfer elicits cardioprotective effects in an angiotensin II infusion rat model of hypertension. Physiological Genomics. 19: 255-61. PMID 15383639 DOI: 10.1152/Physiolgenomics.00170.2004  0.783
2004 Wang G, Anrather J, Huang J, Speth RC, Pickel VM, Iadecola C. NADPH oxidase contributes to angiotensin II signaling in the nucleus tractus solitarius. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5516-24. PMID 15201324 DOI: 10.1523/Jneurosci.1176-04.2004  0.416
2004 McPherson EA, Luo Z, Brown RA, LeBard LS, Corless CC, Speth RC, Bagby SP. Chymase-like angiotensin II-generating activity in end-stage human autosomal dominant polycystic kidney disease. Journal of the American Society of Nephrology : Jasn. 15: 493-500. PMID 14747398 DOI: 10.1097/01.Asn.0000109782.28991.26  0.338
2004 Swenson SJ, Speth RC, Porter JP. Effect of a perinatal high-salt diet on blood pressure control mechanisms in young Sprague-Dawley rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 286: R764-70. PMID 14715490 DOI: 10.1152/Ajpregu.00492.2003  0.457
2004 Barnes R, Speth R. 125I-angiotensin I binding in the rat forebrain. Proceedings of the Western Pharmacology Society. 46: 64-7. PMID 14699888  0.315
2004 Müller D, Mukhopadhyay AK, Speth RC, Guidone G, Potthast R, Potter LR, Middendorff R. Spatiotemporal regulation of the two atrial natriuretic peptide receptors in testis. Endocrinology. 145: 1392-401. PMID 14630722 DOI: 10.1210/En.2003-0706  0.4
2003 Huang J, Hara Y, Anrather J, Speth RC, Iadecola C, Pickel VM. Angiotensin II subtype 1A (AT1A) receptors in the rat sensory vagal complex: subcellular localization and association with endogenous angiotensin. Neuroscience. 122: 21-36. PMID 14596846 DOI: 10.1016/S0306-4522(03)00606-7  0.525
2003 Speth RC. Sarcosine1,glycine8 angiotensin II is an AT1 angiotensin II receptor subtype selective antagonist. Regulatory Peptides. 115: 203-9. PMID 14556962 DOI: 10.1016/S0167-0115(03)00172-1  0.551
2003 Zisman LS, Keller RS, Weaver B, Lin Q, Speth R, Bristow MR, Canver CC. Increased angiotensin-(1-7)-forming activity in failing human heart ventricles: evidence for upregulation of the angiotensin-converting enzyme Homologue ACE2. Circulation. 108: 1707-12. PMID 14504186 DOI: 10.1161/01.Cir.0000094734.67990.99  0.324
2003 Santos RA, Simoes e Silva AC, Maric C, Silva DM, Machado RP, de Buhr I, Heringer-Walther S, Pinheiro SV, Lopes MT, Bader M, Mendes EP, Lemos VS, Campagnole-Santos MJ, Schultheiss HP, Speth R, et al. Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proceedings of the National Academy of Sciences of the United States of America. 100: 8258-63. PMID 12829792 DOI: 10.1073/Pnas.1432869100  0.543
2003 Wright JW, Tamura-Myers E, Wilson WL, Roques BP, Llorens-Cortes C, Speth RC, Harding JW. Conversion of brain angiotensin II to angiotensin III is critical for pressor response in rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 284: R725-33. PMID 12433674 DOI: 10.1152/Ajpregu.00326.2002  0.502
2002 Booz GW, Day JN, Speth R, Baker KM. Cytokine G-protein signaling crosstalk in cardiomyocytes: attenuation of Jak-STAT activation by endothelin-1. Molecular and Cellular Biochemistry. 240: 39-46. PMID 12487370 DOI: 10.1023/A:1020648425895  0.306
2002 Braileanu GT, Simasko SM, Speth RC, Daubert D, Hu J, Mirando MA. Angiotensin II increases intracellular calcium concentration in pig endometrial stromal cells through type 1 angiotensin receptors, but does not stimulate phospholipase C activity or prostaglandin F2alpha secretion. Reproduction, Fertility, and Development. 14: 199-205. PMID 12219942 DOI: 10.1071/Rd02003  0.377
2002 Bagby SP, LeBard LS, Luo Z, Ogden BE, Corless C, McPherson ED, Speth RC. ANG II AT(1) and AT(2) receptors in developing kidney of normal microswine. American Journal of Physiology. Renal Physiology. 283: F755-64. PMID 12217867 DOI: 10.1152/Ajprenal.00313.2001  0.438
2002 Gardi J, Speth RC, Taishi P, Kacsóh B, Obál F, Krueger JM. Alterations in GHRH binding and GHRH receptor mRNA in the pituitary of adult dw/dw rats. Peptides. 23: 1497-502. PMID 12182953 DOI: 10.1016/S0196-9781(02)00088-8  0.38
2002 Gardi J, Taishi P, Speth R, Obal F, Krueger JM. Sleep loss alters hypothalamic growth hormone-releasing hormone receptors in rats. Neuroscience Letters. 329: 69-72. PMID 12161265 DOI: 10.1016/S0304-3940(02)00587-6  0.33
2002 Bagby SP, LeBard LS, Luo Z, Speth RC, Ogden BE, Corless CL. Angiotensin II type 1 and 2 receptors in conduit arteries of normal developing microswine. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 1113-21. PMID 12117725  0.392
2002 Speth RC, Smith MS, Grove KL. Brain angiotensinergic mediation of enhanced water consumption in lactating rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 282: R695-701. PMID 11832388 DOI: 10.1152/Ajpregu.00432.2001  0.393
2002 Moulik S, Speth RC, Turner BB, Rowe BP. Angiotensin II receptor subtype distribution in the rabbit brain. Experimental Brain Research. 142: 275-83. PMID 11807581 DOI: 10.1007/S00221-001-0940-5  0.46
2002 Gardi J, Krueger JM, Speth RC. Preparation and a simple one-step purification of [His1-mono-125I-Tyr10,Nle27] hGHRH(1-32)-NH2 Journal of Labelled Compounds and Radiopharmaceuticals. 45: 13-18. DOI: 10.1002/Jlcr.526  0.323
2001 Szabo Z, Speth RC, Brown PR, Kerenyi L, Kao PF, Mathews WB, Ravert HT, Hilton J, Rauseo P, Dannals RF, Zheng W, Lee S, Sandberg K. Use of positron emission tomography to study AT1 receptor regulation in vivo. Journal of the American Society of Nephrology : Jasn. 12: 1350-8. PMID 11423564  0.354
2001 Speth RC, Smith MS, Grove KL. Lactation decreases angiotensinogen mRNA expression in the midcaudal arcuate nucleus of the rat brain American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 280: R1169-R1176. PMID 11247841 DOI: 10.1152/Ajpregu.2001.280.4.R1169  0.391
2000 Akers WS, Cross A, Speth R, Dwoskin LP, Cassis LA. Renin-angiotensin system and sympathetic nervous system in cardiac pressure-overload hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 279: H2797-806. PMID 11087234 DOI: 10.1152/Ajpheart.2000.279.6.H2797  0.402
2000 Moulik S, Speth RC, Rowe BP. Differential loss in function of angiotensin II receptor subtypes during tissue storage. Life Sciences. 66: PL233-7. PMID 10794504 DOI: 10.1016/S0024-3205(00)00474-4  0.512
2000 Tian Y, Sandberg K, Murase T, Baker EA, Speth RC, Verbalis JG. Vasopressin V2 receptor binding is down-regulated during renal escape from vasopressin-induced antidiuresis. Endocrinology. 141: 307-14. PMID 10614652 DOI: 10.1210/Endo.141.1.7256  0.434
1999 Speth RC, Barry WT, Smith MS, Grove KL. A comparison of brain angiotensin II receptors during lactation and diestrus of the estrous cycle in the rat. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 277: R904-R909. PMID 29587052 DOI: 10.1152/ajpregu.1999.277.3.R904  0.48
1999 Speth RC, Barry WT, Smith MS, Grove KL. A comparison of brain angiotensin II receptors during lactation and diestrus of the estrous cycle in the rat American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 277: R904-R909. PMID 10484510 DOI: 10.1152/Ajpregu.1999.277.3.R904  0.563
1999 Qiu J, Nelson SH, Speth RC, Wang DH. Regulation of adrenal angiotensin receptor subtypes: a possible mechanism for sympathectomy-induced adrenal hypertrophy. Journal of Hypertension. 17: 933-40. PMID 10419066 DOI: 10.1097/00004872-199917070-00009  0.432
1999 Speth RC, Daubert DL, Grove KL. Angiotensin II: a reproductive hormone too? Regulatory Peptides. 79: 25-40. PMID 9930580 DOI: 10.1016/S0167-0115(98)00141-4  0.442
1999 Daubert DL, Meadows GG, Wang JH, Sanchez PJ, Speth RC. Changes in angiotensin II receptors in dopamine-rich regions of the mouse brain with age and ethanol consumption. Brain Research. 816: 8-16. PMID 9878677 DOI: 10.1016/S0006-8993(98)00930-5  0.534
1999 Rowland NE, Crews EC, Young SL, Speth RC. Dietary NaCl during pregnancy and lactation: Effect on brain angiotensin II receptors and behavior Behavioral Neuroscience. 113: 1090-1094. DOI: 10.1037//0735-7044.113.5.1090  0.331
1998 Grove KL, Speth RC, Palmer AA, Ganong WF, Steele MK. Angiotensin II receptor binding sites in the ventral portion of the bed nucleus of the stria terminalis are reduced by interruption of the medial forebrain bundle. Brain Research. 809: 5-11. PMID 9795102 DOI: 10.1016/S0006-8993(98)00769-0  0.525
1998 Grove KL, Speth RC, Senger PL. Angiotensin II as a semen extender component increases retention of spermatozoa within the uterus of the heifer. Reproduction, Fertility, and Development. 9: 545-9. PMID 9418985 DOI: 10.1071/R96124  0.409
1996 Forsyth CS, Speth RC, Wecker L, Galey FD, Frank AA. Comparison of nicotinic receptor binding and biotransformation of coniine in the rat and chick. Toxicology Letters. 89: 175-83. PMID 9001585 DOI: 10.1016/S0378-4274(96)03804-0  0.409
1996 Du Y, Guo DF, Inagami T, Speth RC, Wang DH. Regulation of ANG II-receptor subtype and its gene expression in adrenal gland. The American Journal of Physiology. 271: H440-6. PMID 8770082 DOI: 10.1152/AJPHEART.1996.271.2.H440  0.438
1995 Lu XY, Zhang W, Grove KL, Speth RC. Influence of tissue freezing on the binding of 125I-sarcosine1, isoleucine8 angiotensin II to angiotensin II receptor subtypes in the rat. Journal of Pharmacological and Toxicological Methods. 33: 83-90. PMID 7766920 DOI: 10.1016/1056-8719(94)00061-8  0.383
1995 Rowe BP, Saylor DL, Speth RC, Absher DR. Angiotensin-(1-7) binding at angiotensin II receptors in the rat brain. Regulatory Peptides. 56: 139-46. PMID 7652190 DOI: 10.1016/0167-0115(95)00010-9  0.554
1995 Phillips MI, Wang H, Kimura B, Speth RC, Ghazi N. Brain angiotensin and the female reproductive cycle. Advances in Experimental Medicine and Biology. 377: 357-70. PMID 7484438 DOI: 10.1007/978-1-4899-0952-7_25  0.455
1995 Grove KL, Mayo RJ, Forsyth CS, Frank AA, Speth RC. Fosinopril treatment of pregnant rats: developmental toxicity, fetal angiotensin-converting enzyme inhibition, and fetal angiotensin II receptor regulation. Toxicology Letters. 80: 85-95. PMID 7482596 DOI: 10.1016/0378-4274(95)03346-M  0.508
1994 Ghazi N, Grove KL, Wright JW, Phillips MI, Speth RC. Variations in angiotensin-II release from the rat brain during the estrous cycle. Endocrinology. 135: 1945-50. PMID 7956915 DOI: 10.1210/Endo.135.5.7956915  0.344
1993 Saylor DL, Speth RC, Rowe BP. Effects of peptidase inhibitors on binding at angiotensin receptor subtypes in the rat brain. Biochemical Pharmacology. 45: 2109-14. PMID 8512592 DOI: 10.1016/0006-2952(93)90023-P  0.46
1993 Speth RC. [125I]CGP 42112 binding reveals differences between rat brain and adrenal AT2 receptor binding sites. Regulatory Peptides. 44: 189-97. PMID 8469773 DOI: 10.1016/0167-0115(93)90242-Z  0.523
1993 Cook VI, Grove KL, Speth RC, McMenamin KM, Harding JW. Differences between perinatal angiotensin binding in the brains of SHR and WKY rats Regulatory Peptides. 45: 395-405. PMID 8351405 DOI: 10.1016/0167-0115(93)90366-G  0.503
1993 Grove KL, Speth RC. Angiotensin II and non-angiotensin II displaceable binding sites for [3H]losartan in the rat liver. Biochemical Pharmacology. 46: 1653-60. PMID 8240422 DOI: 10.1016/0006-2952(93)90335-T  0.439
1992 Speth RC, Grove KL, Rowe BP. Angiotensin II and the locus coeruleus. Progress in Brain Research. 88: 217-26. PMID 1726026 DOI: 10.1016/S0079-6123(08)63811-X  0.583
1992 Rowe BP, Saylor DL, Speth RC. Analysis of angiotensin II receptor subtypes in individual rat brain nuclei. Neuroendocrinology. 55: 563-73. PMID 1584339 DOI: 10.1159/000126177  0.485
1992 Grove KL, Cook VI, Speth RC. Angiotensin II receptor development in the bed nucleus of the stria terminalis and other perihypothalamic brain regions of the female and male rat. Neuroendocrinology. 56: 169-77. PMID 1407370 DOI: 10.1159/000126225  0.472
1991 Rowe BP, Grove KL, Saylor DL, Speth RC. Angiotensin II receptor subtypes in the rat brain. European Journal of Pharmacology. 186: 339-42. PMID 2289535 DOI: 10.1016/0014-2999(90)90457-H  0.482
1991 Rowe BP, Saylor DL, Speth RC. Novel angiotensin II binding sites in the mesopontine area of the rat brain. Brain Research. 534: 129-34. PMID 2073578 DOI: 10.1016/0006-8993(90)90122-R  0.51
1991 Rowe BP, Grove KL, Saylor DL, Speth RC. Discrimination of angiotensin II receptor subtype distribution in the rat brain using non-peptidic receptor antagonists. Regulatory Peptides. 33: 45-53. PMID 2047544 DOI: 10.1016/0167-0115(91)90014-8  0.515
1991 Grove KL, Cook VI, Speth RC. Angiotensin II receptors in the ventral portion of the bed nucleus of the stria terminalis. Neuroendocrinology. 53: 339-43. PMID 2046868 DOI: 10.1159/000125739  0.542
1991 Speth RC, Grove KL. Pertussis toxin blocks the dipsogenic actions of carbachol, but does not block the dipsogenic and pressor actions of angiotensin II. Regulatory Peptides. 32: 121-8. PMID 1903550 DOI: 10.1016/0167-0115(91)90040-N  0.428
1991 Speth RC, Rowe BP, Grove KL, Carter MR, Saylor D. Sulfhydryl reducing agents distinguish two subtypes of angiotensin II receptors in the rat brain Brain Research. 548: 1-8. PMID 1868325 DOI: 10.1016/0006-8993(91)91098-L  0.55
1991 Cook VI, Grove KL, McMenamin KM, Carter MR, Harding JW, Speth RC. The AT2 angiotensin receptor subtype predominates in the 18 day gestation fetal rat brain Brain Research. 560: 334-336. PMID 1760741 DOI: 10.1016/0006-8993(91)91254-X  0.514
1990 Speth RC, Kim KH. Discrimination of two angiotensin II receptor subtypes with a selective agonist analogue of angiotensin II, p-aminophenylalanine6 angiotensin II. Biochemical and Biophysical Research Communications. 169: 997-1006. PMID 2194459 DOI: 10.1016/0006-291X(90)91993-3  0.504
1990 Walters DE, Speth RC. Loss of striatal angiotensin-converting enzyme following intrastriatal AF64A is not related to destruction of cholinergic interneurons. Brain Research. 507: 23-7. PMID 2154299 DOI: 10.1016/0006-8993(90)90516-E  0.346
1990 Rowe BP, Kalivas PW, Speth RC. Autoradiographic localization of angiotensin II receptor binding sites on noradrenergic neurons of the locus coeruleus of the rat. Journal of Neurochemistry. 55: 533-40. PMID 2115071 DOI: 10.1111/J.1471-4159.1990.Tb04167.X  0.396
1989 Baksi SN, Abhold RH, Speth RC. Low-calcium diet increases blood pressure and alters peripheral but not central angiotensin II binding sites in rats. Journal of Hypertension. 7: 423-7. PMID 2768829 DOI: 10.1097/00004872-198905000-00012  0.362
1989 Grove KL, Speth RC. Rat epididymis contains functional angiotensin II receptors. Endocrinology. 125: 223-30. PMID 2737144 DOI: 10.1210/Endo-125-1-223  0.5
1989 Hsieh KH, LaHann TR, Speth RC. Topographic probes of angiotensin and receptor: potent angiotensin II agonist containing diphenylalanine and long-acting antagonists containing biphenylalanine and 2-indan amino acid in position 8. Journal of Medicinal Chemistry. 32: 898-903. PMID 2704034 DOI: 10.1021/Jm00124A028  0.506
1989 Walters DE, Speth RC. Monoamine depletion does not alter angiotensin II binding sites in the rat brain. Brain Research Bulletin. 22: 283-8. PMID 2495846 DOI: 10.1016/0361-9230(89)90055-5  0.499
1988 Walters DE, Speth RC. Neuronal localization of specific angiotensin II binding sites in the rat inferior olivary nucleus. Journal of Neurochemistry. 50: 812-7. PMID 3339355 DOI: 10.1111/j.1471-4159.1988.tb02985.x  0.359
1988 Ladenheim EE, Speth RC, Ritter RC. Reduction of CCK-8 binding in the nucleus of the solitary tract in unilaterally nodosectomized rats. Brain Research. 474: 125-9. PMID 3214705 DOI: 10.1016/0006-8993(88)90675-0  0.413
1988 White SR, Penner JD, Speth RC, Chan JY. Angiotensin II receptors in the lumbar spinal cord of the rat. Brain Research. 441: 195-201. PMID 2896050 DOI: 10.1016/0006-8993(88)91398-4  0.395
1988 Speth RC, Husain A. Distribution of angiotensin-converting enzyme and angiotensin II-receptor binding sites in the rat ovary Biology of Reproduction. 38: 695-702. PMID 2837296 DOI: 10.1095/Biolreprod38.3.695  0.525
1987 Speth RC, Dinh TT, Ritter S. Nodose ganglionectomy reduces angiotensin II receptor binding in the rat brainstem Peptides. 8: 677-685. PMID 3628083 DOI: 10.1016/0196-9781(87)90043-X  0.574
1987 Gehlert DR, Speth RC, Wamsley JK. Quantitative autoradiography of angiotensin II receptors in the SHR brain. Peptides. 7: 1021-7. PMID 3562315 DOI: 10.1016/0196-9781(86)90132-4  0.575
1987 Husain A, Bumpus FM, De Silva P, Speth RC. Localization of angiotensin II receptors in ovarian follicles and the identification of angiotensin II in rat ovaries. Proceedings of the National Academy of Sciences of the United States of America. 84: 2489-93. PMID 3470807 DOI: 10.1073/pnas.84.8.2489  0.449
1987 Husain A, DeSilva P, Speth RC, Bumpus FM. Regulation of angiotensin II in rat adrenal gland. Circulation Research. 60: 640-8. PMID 3297386 DOI: 10.1161/01.Res.60.5.640  0.55
1986 Singh R, Harding JW, Speth RC. Effect of intraventricular infusion of an angiotensin II antagonist on 125I-angiotensin II binding in rats. European Journal of Pharmacology. 120: 319-27. PMID 3948923 DOI: 10.1016/0014-2999(86)90472-3  0.442
1986 Speth RC, Bumpus FM, Husain A. Identification of angiotensin II receptors in the rat ovary. European Journal of Pharmacology. 130: 351-2. PMID 3792456 DOI: 10.1016/0014-2999(86)90293-1  0.452
1986 Gehlert DR, Speth RC, Wamsley JK. Distribution of [125I]angiotensin II binding sites in the rat brain: a quantitative autoradiographic study. Neuroscience. 18: 837-56. PMID 3762929 DOI: 10.1016/0306-4522(86)90104-1  0.561
1985 Gehlert DR, Speth RC, Wamsley JK. In vitro autoradiographic localization of [125I]-angiotensin II binding sites in the rat and dog kidney. Peptides. 5: 1043-8. PMID 6099555 DOI: 10.1016/0196-9781(84)90168-2  0.39
1985 Speth RC, Harik SI. Angiotensin II receptor binding sites in brain microvessels. Proceedings of the National Academy of Sciences of the United States of America. 82: 6340-3. PMID 2994072 DOI: 10.1073/Pnas.82.18.6340  0.516
1985 Speth RC, Wamsley JK, Gehlert DR, Chernicky CL, Barnes KL, Ferrario CM. Angiotensin II receptor localization in the canine CNS. Brain Research. 326: 137-43. PMID 2982457 DOI: 10.1016/0006-8993(85)91392-7  0.434
1984 Singh R, Husain A, Ferrario CM, Speth RC. Rat brain angiotensin II receptors: effects of intracerebroventricular angiotensin II infusion. Brain Research. 303: 133-9. PMID 6329469 DOI: 10.1016/0006-8993(84)90220-8  0.46
1984 Speth RC, Singh R, Smeby RR, Ferrario CM, Husain A. Restricted dietary sodium intake alters peripheral but not central angiotensin II receptors. Neuroendocrinology. 38: 387-92. PMID 6328346 DOI: 10.1159/000123922  0.543
1984 Gehlert DR, Speth RC, Healy DP, Wamsley JK. Autoradiographic localization of angiotensin II receptors in the rat brainstem. Life Sciences. 34: 1565-71. PMID 6325840 DOI: 10.1016/0024-3205(84)90611-8  0.444
1984 Gehlert DR, Speth RC, Wamsley JK. Autoradiographic localization of angiotensin II receptors in the rat brain and kidney. European Journal of Pharmacology. 98: 145-6. PMID 6325206 DOI: 10.1016/0014-2999(84)90122-5  0.434
1984 Speth RC, Vallotton MB, Wamsley JK, Khosla MC, Chernicky CL, Bumpus FM, Ferrario CM. Localization of angiotensin receptors in the canine CNS. Clinical and Experimental Hypertension. Part a, Theory and Practice. 6: 1749-53. PMID 6099763 DOI: 10.3109/10641968409046071  0.327
1983 Husain A, Bumpus FM, Smeby RR, Brosnihan KB, Khosla MC, Speth RC, Ferrario CM. Evidence for the existence of a family of biologically active angiotensin I-like peptides in the dog central nervous system Circulation Research. 52: 460-464. PMID 6339108 DOI: 10.1161/01.Res.52.4.460  0.313
1983 Suzuki H, Ferrario CM, Speth RC, Brosnihan KB, Smeby RR, de Silva P. Alterations in plasma and cerebrospinal fluid norepinephrine and angiotensin II during the development of renal hypertension in conscious dogs. Hypertension (Dallas, Tex. : 1979). 5: I139-48. PMID 6337956 DOI: 10.1161/01.Hyp.5.2_Pt_2.I139  0.355
1982 Brosnihan KB, Ferrario CM, Saavedra JM, Speth RC. Catecholamines and serotonin in the area postrema of normal and sodium-depleted dogs. Hypertension (Dallas, Tex. : 1979). 3: II-151-4. PMID 7028613 DOI: 10.1161/01.Hyp.3.6_Pt_2.Ii-151  0.301
1979 Speth RC, Bresolin N, Yamamura HI. Acute diazepam administration produces rapid increases in brain benzodiazepine receptor density European Journal of Pharmacology. 59: 159-160. PMID 510397 DOI: 10.1016/0014-2999(79)90041-4  0.377
1979 Speth RC, Yamamura HI. On the ability of choline and its analogues to interact with muscarinic cholinergic receptors in the rat brain European Journal of Pharmacology. 58: 197-201. PMID 499350 DOI: 10.1016/0014-2999(79)90012-8  0.319
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