| Year |
Citation |
Score |
| 2024 |
Singh M, Indurthi DC, Mittal L, Auerbach A, Asthana S. Conformational dynamics of a nicotinic receptor neurotransmitter site. Elife. 13. PMID 39693137 DOI: 10.7554/eLife.92418 |
0.387 |
|
| 2024 |
Auerbach A. Dynamics of receptor activation by agonists. Biophysical Journal. PMID 38178577 DOI: 10.1016/j.bpj.2024.01.003 |
0.454 |
|
| 2023 |
Kumari M, Khatoon N, Sharma R, Adusumilli S, Auerbach A, Kashyap HK, Nayak TK. Mechanism of hydrophobic gating in the acetylcholine receptor channel pore. The Journal of General Physiology. 156. PMID 38153395 DOI: 10.1085/jgp.202213189 |
0.505 |
|
| 2023 |
Indurthi DC, Auerbach A. Agonist efficiency links binding and gating in a nicotinic receptor. Elife. 12. PMID 37399234 DOI: 10.7554/eLife.86496 |
0.403 |
|
| 2021 |
Indurthi DC, Auerbach A. Agonist efficiency from concentration-response curves: Structural implications and applications. Biophysical Journal. PMID 33675765 DOI: 10.1016/j.bpj.2021.02.034 |
0.331 |
|
| 2020 |
Auerbach A. Pathways for nicotinic receptor desensitization. The Journal of General Physiology. 152. PMID 32910188 DOI: 10.1085/jgp.202012639 |
0.545 |
|
| 2020 |
Nayak TK, Vij R, Bruhova I, Shandilya J, Auerbach A. Correction: Efficiency measures the conversion of agonist binding energy into receptor conformational change. The Journal of General Physiology. 152. PMID 31816639 DOI: 10.1085/Jgp.20181221511252019C |
0.432 |
|
| 2020 |
Gnanasambandam R, Auerbach A. Probability of Opening During Recovery From AChR Desensitization Biophysical Journal. 118: 584a. DOI: 10.1016/j.bpj.2019.11.3166 |
0.326 |
|
| 2019 |
Tripathy S, Zheng W, Auerbach A. A single molecular distance predicts agonist binding energy in nicotinic receptors. The Journal of General Physiology. PMID 30635370 DOI: 10.1085/Jgp.201812212 |
0.461 |
|
| 2019 |
Nayak TK, Vij R, Bruhova I, Shandilya J, Auerbach A. Efficiency measures the conversion of agonist binding energy into receptor conformational change. The Journal of General Physiology. PMID 30635369 DOI: 10.1085/Jgp.201812215 |
0.511 |
|
| 2019 |
Tripathy S, Muehlemann SM, Zheng W, Auerbach A. Structural Correlates of Agonist Binding to Neurotransmitter Binding Sites Biophysical Journal. 116: 529a. DOI: 10.1016/J.Bpj.2018.11.2851 |
0.377 |
|
| 2019 |
Tripathy S, Zheng W, Auerbach A. Structure Meets Function: Agonist Actions at Neurotransmitter Binding Sites Biophysical Journal. 116: 394a. DOI: 10.1016/J.Bpj.2018.11.2131 |
0.365 |
|
| 2019 |
Gnanasambandam R, Auerbach A. Probability of Opening during Recovery from Acetylcholine Receptor Desensitization Biophysical Journal. 116: 394a. DOI: 10.1016/j.bpj.2018.11.2130 |
0.404 |
|
| 2018 |
Tripathy S, Zheng W, Auerbach A. Simulations Suggest a Structural Basis for Nicotinic Receptor Activation by Agonists Biophysical Journal. 114: 48a. DOI: 10.1016/J.Bpj.2017.11.314 |
0.351 |
|
| 2018 |
Auerbach A, Nayak TK. Agonist Binding to Endplate AChRs: MWC Is A-Ok Biophysical Journal. 114: 297a-298a. DOI: 10.1016/j.bpj.2017.11.1698 |
0.394 |
|
| 2017 |
Nayak TK, Auerbach A. Cyclic activation of endplate acetylcholine receptors. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078356 DOI: 10.1073/pnas.1711228114 |
0.499 |
|
| 2017 |
Gupta S, Chakraborty S, Vij R, Nayak TK, Auerbach A. Acetylcholine Receptor Gating: Click-Twist-Tilt-Rip-Pop Biophysical Journal. 112: 552a. DOI: 10.1016/J.Bpj.2016.11.2981 |
0.675 |
|
| 2016 |
Gupta S, Chakraborty S, Vij R, Auerbach A. A mechanism for acetylcholine receptor gating based on structure, coupling, phi, and flip. The Journal of General Physiology. PMID 27932572 DOI: 10.1085/Jgp.201611673 |
0.75 |
|
| 2016 |
Bruhova I, Auerbach A. Molecular recognition at cholinergic synapses: Acetylcholine versus choline. The Journal of Physiology. PMID 27779761 DOI: 10.1113/JP273291 |
0.483 |
|
| 2016 |
Nayak TK, Chakraborty S, Zheng W, Auerbach A. Structural correlates of affinity in fetal versus adult endplate nicotinic receptors. Nature Communications. 7: 11352. PMID 27101778 DOI: 10.1038/Ncomms11352 |
0.455 |
|
| 2016 |
Gupta S, Chakraborty S, Auerbach A. Between the Sheets: Inter-Subunit Backbone Interactions at AChR Neurotransmitter Binding Sites Biophysical Journal. 110: 604a. DOI: 10.1016/J.Bpj.2015.11.3228 |
0.699 |
|
| 2016 |
Nayak TK, Auerbach A. Interactome Maps of the Acetylcholine Receptor Gate Region Biophysical Journal. 110: 604a. DOI: 10.1016/j.bpj.2015.11.3226 |
0.449 |
|
| 2016 |
Auerbach A, Nayak TK. Fundamental Constants for Activation of Human Endplate Receptors Biophysical Journal. 110: 604a. DOI: 10.1016/j.bpj.2015.11.3224 |
0.433 |
|
| 2016 |
Chakraborty S, Auerbach A. Simulations of Endplate AChRs: Agonist Site β-Sheet and M1 π-Helix Biophysical Journal. 110: 603a-604a. DOI: 10.1016/j.bpj.2015.11.3223 |
0.434 |
|
| 2016 |
Bruhova I, Auerbach A. Molecular Determinants of Partial agonist Affinity in Adult Neuromuscular Acetylcholine Receptors Biophysical Journal. 110: 202a. DOI: 10.1016/j.bpj.2015.11.1126 |
0.522 |
|
| 2015 |
Auerbach A. Dose-Response Analysis When There is a Correlation between Affinity and Efficacy. Molecular Pharmacology. PMID 26655305 DOI: 10.1124/mol.115.102509 |
0.451 |
|
| 2015 |
Vij R, Purohit P, Auerbach A. Modal affinities of endplate acetylcholine receptors caused by loop C mutations. The Journal of General Physiology. 146: 375-86. PMID 26503719 DOI: 10.1085/jgp.201511503 |
0.514 |
|
| 2015 |
Auerbach A. Activation of endplate nicotinic acetylcholine receptors by agonists. Biochemical Pharmacology. 97: 601-8. PMID 26206191 DOI: 10.1016/j.bcp.2015.06.024 |
0.511 |
|
| 2015 |
Purohit P, Chakraborty S, Auerbach A. Function of the M1 π-helix in endplate receptor activation and desensitization. The Journal of Physiology. 593: 2851-66. PMID 25929452 DOI: 10.1113/JP270223 |
0.446 |
|
| 2015 |
Auerbach A. Agonist activation of a nicotinic acetylcholine receptor. Neuropharmacology. 96: 150-6. PMID 25446670 DOI: 10.1016/j.neuropharm.2014.10.004 |
0.554 |
|
| 2015 |
Vihani A, Purohit P, Auerbach A. The Role of the M3 Helix in AChR Gating and PAM Action Biophysical Journal. 108: 430a. DOI: 10.1016/j.bpj.2014.11.2351 |
0.511 |
|
| 2015 |
Nayak TK, Auerbach A. Differences in Agonist Energy at the Neurotransmitter Binding Sites in the Neuromuscular Acetylcholine Receptors Biophysical Journal. 108: 429a-430a. DOI: 10.1016/J.BPJ.2014.11.2348 |
0.481 |
|
| 2015 |
Chakraborty S, Nayak TK, Bruhova I, Zheng W, Auerbach AL. Molecular Simulations of Muscle AChR Agonist Binding Sites Biophysical Journal. 108: 429a. DOI: 10.1016/J.Bpj.2014.11.2347 |
0.345 |
|
| 2015 |
Gupta S, Purohit P, Auerbach A. Is the AChR a Cuckoo-Clock? Local and Remote Interactions of the α M2-3 Linker in Gating Biophysical Journal. 108: 429a. DOI: 10.1016/J.Bpj.2014.11.2346 |
0.74 |
|
| 2015 |
Auerbach A. Thermodynamics of AChR Activation Biophysical Journal. 108: 8a. DOI: 10.1016/j.bpj.2014.11.068 |
0.563 |
|
| 2014 |
Nayak TK, Bruhova I, Chakraborty S, Gupta S, Zheng W, Auerbach A. Functional differences between neurotransmitter binding sites of muscle acetylcholine receptors. Proceedings of the National Academy of Sciences of the United States of America. 111: 17660-5. PMID 25422413 DOI: 10.1073/Pnas.1414378111 |
0.703 |
|
| 2014 |
Purohit P, Bruhova I, Gupta S, Auerbach A. Catch-and-hold activation of muscle acetylcholine receptors having transmitter binding site mutations. Biophysical Journal. 107: 88-99. PMID 24988344 DOI: 10.1016/J.Bpj.2014.04.057 |
0.717 |
|
| 2014 |
Nayak TK, Gupta S, Auerbach A. Functional Asymmetry of Agonist Binding in Fetal and Adult Muscle Acetylcholine Receptors Biophysical Journal. 106: 339a. DOI: 10.1016/J.Bpj.2013.11.1941 |
0.703 |
|
| 2014 |
Gupta S, Auerbach A. Gating Phi Values in the Muscle Acetylcholine Receptor αM2-αM3 Linker with vs. without Agonists Biophysical Journal. 106: 339a. DOI: 10.1016/J.Bpj.2013.11.1940 |
0.752 |
|
| 2014 |
Purohit P, Gupta S, Jadey S, Auerbach A. Energy Maps of Acetylcholine Receptor Gating Biophysical Journal. 106: 339a. DOI: 10.1016/J.Bpj.2013.11.1939 |
0.841 |
|
| 2014 |
Purohit P, Gupta S, Bruhova I, Auerbach A. Linear Free Energy Relationships for Neurotransmitter Binding to a Nicotinic Acetylcholine Receptor Biophysical Journal. 106: 339a. DOI: 10.1016/J.Bpj.2013.11.1938 |
0.719 |
|
| 2013 |
Purohit P, Gupta S, Jadey S, Auerbach A. Functional anatomy of an allosteric protein. Nature Communications. 4: 2984. PMID 24352193 DOI: 10.1038/Ncomms3984 |
0.842 |
|
| 2013 |
Nayak TK, Auerbach A. Asymmetric transmitter binding sites of fetal muscle acetylcholine receptors shape their synaptic response. Proceedings of the National Academy of Sciences of the United States of America. 110: 13654-9. PMID 23898191 DOI: 10.1073/pnas.1308247110 |
0.46 |
|
| 2013 |
Gupta S, Purohit P, Auerbach A. Function of interfacial prolines at the transmitter-binding sites of the neuromuscular acetylcholine receptor. The Journal of Biological Chemistry. 288: 12667-79. PMID 23519471 DOI: 10.1074/Jbc.M112.443911 |
0.738 |
|
| 2013 |
Purohit P, Auerbach A. Loop C and the mechanism of acetylcholine receptor-channel gating. The Journal of General Physiology. 141: 467-78. PMID 23478996 DOI: 10.1085/jgp.201210946 |
0.594 |
|
| 2013 |
Bruhova I, Gregg T, Auerbach A. Energy for wild-type acetylcholine receptor channel gating from different choline derivatives. Biophysical Journal. 104: 565-74. PMID 23442907 DOI: 10.1016/j.bpj.2012.11.3833 |
0.515 |
|
| 2013 |
Auerbach A. The energy and work of a ligand-gated ion channel. Journal of Molecular Biology. 425: 1461-75. PMID 23357172 DOI: 10.1016/j.jmb.2013.01.027 |
0.574 |
|
| 2013 |
Jadey S, Purohit P, Auerbach A. Action of nicotine and analogs on acetylcholine receptors having mutations of transmitter-binding site residue αG153. The Journal of General Physiology. 141: 95-104. PMID 23277476 DOI: 10.1085/Jgp.201210896 |
0.833 |
|
| 2013 |
Gupta S, Purohit P, Auerbach A. Erratum: Function of interfacial prolines at the transmitter-binding sites of the neuromuscular acetylcholine receptor (Journal of Biological Chemistry (2013) 288 (12667-12679)) Journal of Biological Chemistry. 288. DOI: 10.1074/Jbc.A112.443911 |
0.665 |
|
| 2013 |
Purohit PG, Auerbach A. Loop-C and a Cyclic Activation Scheme for Acetylcholine Receptor-Channels (AChRs) Biophysical Journal. 104: 634a. DOI: 10.1016/j.bpj.2012.11.3503 |
0.537 |
|
| 2013 |
Gupta S, Purohit P, Auerbach A. Proline Residues at the Nicotinic Acetylcholine Transmitter Binding Sites Biophysical Journal. 104: 275a. DOI: 10.1016/J.Bpj.2012.11.1543 |
0.711 |
|
| 2012 |
Jadey S, Auerbach A. An integrated catch-and-hold mechanism activates nicotinic acetylcholine receptors. The Journal of General Physiology. 140: 17-28. PMID 22732309 DOI: 10.1085/Jgp.201210801 |
0.852 |
|
| 2012 |
Purohit P, Bruhova I, Auerbach A. Sources of energy for gating by neurotransmitters in acetylcholine receptor channels. Proceedings of the National Academy of Sciences of the United States of America. 109: 9384-9. PMID 22647603 DOI: 10.1073/pnas.1203633109 |
0.55 |
|
| 2012 |
Nayak TK, Purohit PG, Auerbach A. The intrinsic energy of the gating isomerization of a neuromuscular acetylcholine receptor channel. The Journal of General Physiology. 139: 349-58. PMID 22547665 DOI: 10.1085/jgp.201110752 |
0.557 |
|
| 2012 |
Jha A, Gupta S, Zucker SN, Auerbach A. The energetic consequences of loop 9 gating motions in acetylcholine receptor-channels. The Journal of Physiology. 590: 119-29. PMID 22025664 DOI: 10.1113/Jphysiol.2011.213892 |
0.736 |
|
| 2012 |
Auerbach A. Thinking in cycles: MWC is a good model for acetylcholine receptor-channels. The Journal of Physiology. 590: 93-8. PMID 21807612 DOI: 10.1113/jphysiol.2011.214684 |
0.597 |
|
| 2012 |
Jadey SV, Auerbach A. Introducing Kappa: An Integrated, ‘Catch-And-Hold’ Reaction Co-Ordinate that Triggers AChR Gating Biophysical Journal. 102: 119a-120a. DOI: 10.1016/J.Bpj.2011.11.670 |
0.851 |
|
| 2012 |
Gupta S, Purohit P, Auerbach A. Effects of Mutations of Proline Residues Located in the Complementary Subunit of the Acetylcholine Receptor Transmitter Binding Site Biophysical Journal. 102: 119a. DOI: 10.1016/J.Bpj.2011.11.669 |
0.757 |
|
| 2012 |
Purohit PG, Auerbach A. On the Complexity of the Kinetics of Unliganded Gating in Neuromuscular Acetylcholine Receptor-Channels Biophysical Journal. 102: 119a. DOI: 10.1016/j.bpj.2011.11.668 |
0.579 |
|
| 2012 |
Nayak TK, Purohit P, Auerbach A. New Estimates for the ‘Allosteric’ Constant of Neuromuscular Acetylcholine Receptor-Channels Biophysical Journal. 102: 119a. DOI: 10.1016/j.bpj.2011.11.666 |
0.491 |
|
| 2012 |
Bruhova I, Purohit P, Auerbach A. Sources of Energy for Gating by Agonists in Acetylcholine Receptor-Channels Biophysical Journal. 102: 118a. DOI: 10.1016/j.bpj.2011.11.663 |
0.52 |
|
| 2011 |
Jadey SV, Purohit P, Bruhova I, Gregg TM, Auerbach A. Design and control of acetylcholine receptor conformational change. Proceedings of the National Academy of Sciences of the United States of America. 108: 4328-33. PMID 21368211 DOI: 10.1073/Pnas.1016617108 |
0.85 |
|
| 2011 |
Gupta S, Auerbach A. Mapping heat exchange in an allosteric protein. Biophysical Journal. 100: 904-11. PMID 21320434 DOI: 10.1016/J.Bpj.2010.12.3739 |
0.72 |
|
| 2011 |
Gupta S, Auerbach A. Temperature dependence of acetylcholine receptor channels activated by different agonists. Biophysical Journal. 100: 895-903. PMID 21320433 DOI: 10.1016/J.Bpj.2010.12.3727 |
0.73 |
|
| 2011 |
Zheng W, Auerbach A. Decrypting the sequence of structural events during the gating transition of pentameric ligand-gated ion channels based on an interpolated elastic network model. Plos Computational Biology. 7: e1001046. PMID 21253563 DOI: 10.1371/Journal.Pcbi.1001046 |
0.525 |
|
| 2011 |
Purohit P, Auerbach A. Glycine hinges with opposing actions at the acetylcholine receptor-channel transmitter binding site. Molecular Pharmacology. 79: 351-9. PMID 21115636 DOI: 10.1124/mol.110.068767 |
0.578 |
|
| 2011 |
Bruhova I, Gregg T, Auerbach A. Why is Choline Such a Low-Efficacy Agonist of the Neuromuscular Acetylcholine Receptor-Channel? Biophysical Journal. 100: 347a. DOI: 10.1016/j.bpj.2010.12.2095 |
0.583 |
|
| 2011 |
Purohit PG, Auerbach A. Glycine Hinges with Opposing Roles at the Acetylcholine Receptor-Channel Transmitter Binding Site Biophysical Journal. 100: 276a. DOI: 10.1016/J.BPJ.2010.12.1718 |
0.592 |
|
| 2011 |
Nayak TK, Auerbach A. Energy Changes at the Acetylcholine Receptor Gate Region Biophysical Journal. 100: 276a. DOI: 10.1016/j.bpj.2010.12.1714 |
0.552 |
|
| 2011 |
Gupta S, Auerbach A. Molecular Thermography: Mapping Enthalpy and Entropy Changes in Acetylcholine Receptor Gating Biophysical Journal. 100: 274a. DOI: 10.1016/J.Bpj.2010.12.1708 |
0.731 |
|
| 2011 |
Jadey SV, Purohit P, Bruhova I, Gregg T, Auerbach A. Estimating Agonist Efficacy by Engineering Acetylcholine Receptor-Channels Biophysical Journal. 100: 274a. DOI: 10.1016/J.Bpj.2010.12.1707 |
0.856 |
|
| 2010 |
Bruhova I, Auerbach A. Subunit symmetry at the extracellular domain-transmembrane domain interface in acetylcholine receptor channel gating. The Journal of Biological Chemistry. 285: 38898-904. PMID 20864527 DOI: 10.1074/jbc.M110.169110 |
0.574 |
|
| 2010 |
Cadugan DJ, Auerbach A. Linking the acetylcholine receptor-channel agonist-binding sites with the gate. Biophysical Journal. 99: 798-807. PMID 20682257 DOI: 10.1016/j.bpj.2010.05.008 |
0.845 |
|
| 2010 |
Jha A, Auerbach A. Acetylcholine receptor channels activated by a single agonist molecule. Biophysical Journal. 98: 1840-6. PMID 20441747 DOI: 10.1016/j.bpj.2010.01.025 |
0.551 |
|
| 2010 |
Purohit P, Auerbach A. Energetics of gating at the apo-acetylcholine receptor transmitter binding site. The Journal of General Physiology. 135: 321-31. PMID 20351060 DOI: 10.1085/jgp.200910384 |
0.577 |
|
| 2010 |
Auerbach A. The gating isomerization of neuromuscular acetylcholine receptors. The Journal of Physiology. 588: 573-86. PMID 19933754 DOI: 10.1113/jphysiol.2009.182774 |
0.565 |
|
| 2010 |
Jadey SV, Purohit P, Gregg T, Auerbach A. Energy Changes for Small Molecules at the Acetylcholine Receptor-Channel Transmitter Binding Site Biophysical Journal. 98: 132a. DOI: 10.1016/J.Bpj.2009.12.714 |
0.825 |
|
| 2010 |
Gupta S, Jadey S, Purohit P, Auerbach A. The N Terminal M2 Cap of Nicotinic Acetylcholine Receptors Biophysical Journal. 98: 131a-132a. DOI: 10.1016/J.Bpj.2009.12.711 |
0.822 |
|
| 2010 |
Bruhova I, Jha A, Auerbach A. Dynamics of Acetylcholine Receptor-Channel Gating: Pre-M1 of the Epsilon Subunit Biophysical Journal. 98: 131a. DOI: 10.1016/j.bpj.2009.12.709 |
0.545 |
|
| 2010 |
Purohit P, Auerbach A. Mutations at Ag153 in Nicotinic Acetylcholine Receptors increase the Un-Liganded Gating Equilibrium Constant Biophysical Journal. 98: 131a. DOI: 10.1016/j.bpj.2009.12.707 |
0.47 |
|
| 2010 |
Purohit P, Cadugan D, Auerbach A. Estimation of Phi-Values for the Am1 Domain of Neuromuscular Acetylcholine Receptors Biophysical Journal. 98: 130a. DOI: 10.1016/j.bpj.2009.12.705 |
0.824 |
|
| 2009 |
Jha A, Purohit P, Auerbach A. Energy and structure of the M2 helix in acetylcholine receptor-channel gating. Biophysical Journal. 96: 4075-84. PMID 19450479 DOI: 10.1016/j.bpj.2009.02.030 |
0.579 |
|
| 2009 |
Bafna PA, Jha A, Auerbach A. Aromatic Residues {epsilon}Trp-55 and {delta}Trp-57 and the Activation of Acetylcholine Receptor Channels. The Journal of Biological Chemistry. 284: 8582-8. PMID 19171937 DOI: 10.1074/jbc.M807152200 |
0.622 |
|
| 2009 |
Purohit P, Auerbach A. Unliganded gating of acetylcholine receptor channels. Proceedings of the National Academy of Sciences of the United States of America. 106: 115-20. PMID 19114650 DOI: 10.1073/pnas.0809272106 |
0.561 |
|
| 2009 |
Purohit PG, Auerbach A. The Unliganded Gating Mechanism Of Nicotinic Acetylcholine Receptors Biophysical Journal. 96: 166a-167a. DOI: 10.1016/j.bpj.2008.12.769 |
0.558 |
|
| 2009 |
Jadey SV, Purohit P, Auerbach A. βM2 of The Neuromuscular AChR: Gating, Desensitization and Orientation Biophysical Journal. 96: 166a. DOI: 10.1016/J.Bpj.2008.12.768 |
0.836 |
|
| 2009 |
Cadugan DJ, Chen L, Auerbach A. Interaction Between Two Domains in the AChR Gating Reaction Biophysical Journal. 96: 166a. DOI: 10.1016/J.Bpj.2008.12.767 |
0.838 |
|
| 2009 |
Gupta S, Auerbach A. Temperature Dependence And Activation Energy of nAChR Gating Biophysical Journal. 96: 166a. DOI: 10.1016/J.Bpj.2008.12.766 |
0.719 |
|
| 2008 |
Pollak E, Auerbach A, Talkner P. Observations on rate theory for rugged energy landscapes. Biophysical Journal. 95: 4258-65. PMID 18658228 DOI: 10.1529/Biophysj.108.136358 |
0.311 |
|
| 2008 |
Bafna PA, Purohit PG, Auerbach A. Gating at the mouth of the acetylcholine receptor channel: energetic consequences of mutations in the alphaM2-cap. Plos One. 3: e2515. PMID 18575616 DOI: 10.1371/journal.pone.0002515 |
0.623 |
|
| 2007 |
Purohit P, Auerbach A. Acetylcholine receptor gating: movement in the alpha-subunit extracellular domain. The Journal of General Physiology. 130: 569-79. PMID 18040059 DOI: 10.1085/jgp.200709858 |
0.542 |
|
| 2007 |
Purohit P, Auerbach A. Acetylcholine receptor gating at extracellular transmembrane domain interface: the "pre-M1" linker. The Journal of General Physiology. 130: 559-68. PMID 18040058 DOI: 10.1085/jgp.200709857 |
0.461 |
|
| 2007 |
Jha A, Cadugan DJ, Purohit P, Auerbach A. Acetylcholine receptor gating at extracellular transmembrane domain interface: the cys-loop and M2-M3 linker. The Journal of General Physiology. 130: 547-58. PMID 18040057 DOI: 10.1085/Jgp.200709856 |
0.817 |
|
| 2007 |
Auerbach A. How to turn the reaction coordinate into time. The Journal of General Physiology. 130: 543-6. PMID 18040056 DOI: 10.1085/jgp.200709898 |
0.448 |
|
| 2007 |
Cadugan DJ, Auerbach A. Conformational dynamics of the alphaM3 transmembrane helix during acetylcholine receptor channel gating. Biophysical Journal. 93: 859-65. PMID 17513382 DOI: 10.1529/Biophysj.107.105171 |
0.848 |
|
| 2007 |
Purohit P, Mitra A, Auerbach A. A stepwise mechanism for acetylcholine receptor channel gating. Nature. 446: 930-3. PMID 17443187 DOI: 10.1038/nature05721 |
0.742 |
|
| 2006 |
Lema GM, Auerbach A. Modes and models of GABA(A) receptor gating. The Journal of Physiology. 572: 183-200. PMID 16455693 DOI: 10.1113/jphysiol.2005.099093 |
0.798 |
|
| 2005 |
Mitra A, Cymes GD, Auerbach A. Dynamics of the acetylcholine receptor pore at the gating transition state. Proceedings of the National Academy of Sciences of the United States of America. 102: 15069-74. PMID 16217024 DOI: 10.1073/pnas.0505090102 |
0.711 |
|
| 2005 |
Zhou Y, Pearson JE, Auerbach A. Phi-value analysis of a linear, sequential reaction mechanism: theory and application to ion channel gating. Biophysical Journal. 89: 3680-5. PMID 16183877 DOI: 10.1529/Biophysj.105.067215 |
0.508 |
|
| 2005 |
Auerbach A, Zhou Y. Gating reaction mechanisms for NMDA receptor channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7914-23. PMID 16135748 DOI: 10.1523/Jneurosci.1471-05.2005 |
0.513 |
|
| 2005 |
Mitra A, Tascione R, Auerbach A, Licht S. Plasticity of acetylcholine receptor gating motions via rate-energy relationships. Biophysical Journal. 89: 3071-8. PMID 16113115 DOI: 10.1529/Biophysj.105.068783 |
0.75 |
|
| 2005 |
Auerbach A. Gating of acetylcholine receptor channels: brownian motion across a broad transition state. Proceedings of the National Academy of Sciences of the United States of America. 102: 1408-12. PMID 15665102 DOI: 10.1073/pnas.0406787102 |
0.514 |
|
| 2005 |
Chakrapani S, Auerbach A. A speed limit for conformational change of an allosteric membrane protein. Proceedings of the National Academy of Sciences of the United States of America. 102: 87-92. PMID 15618401 DOI: 10.1073/pnas.0406777102 |
0.743 |
|
| 2004 |
Mitra A, Bailey TD, Auerbach AL. Structural dynamics of the M4 transmembrane segment during acetylcholine receptor gating. Structure (London, England : 1993). 12: 1909-18. PMID 15458639 DOI: 10.1016/j.str.2004.08.004 |
0.677 |
|
| 2004 |
Popescu G, Robert A, Howe JR, Auerbach A. Reaction mechanism determines NMDA receptor response to repetitive stimulation. Nature. 430: 790-3. PMID 15306812 DOI: 10.1038/nature02775 |
0.704 |
|
| 2004 |
Popescu G, Auerbach A. The NMDA receptor gating machine: lessons from single channels. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 10: 192-8. PMID 15155058 DOI: 10.1177/1073858404263483 |
0.685 |
|
| 2004 |
Chakrapani S, Bailey TD, Auerbach A. Gating dynamics of the acetylcholine receptor extracellular domain. The Journal of General Physiology. 123: 341-56. PMID 15051806 DOI: 10.1085/jgp.200309004 |
0.735 |
|
| 2003 |
Chakrapani S, Bailey TD, Auerbach A. The role of loop 5 in acetylcholine receptor channel gating. The Journal of General Physiology. 122: 521-39. PMID 14557402 DOI: 10.1085/jgp.200308885 |
0.765 |
|
| 2003 |
Auerbach A. Life at the top: the transition state of AChR gating. Science's Stke : Signal Transduction Knowledge Environment. 2003: re11. PMID 12824477 DOI: 10.1126/stke.2003.188.re11 |
0.551 |
|
| 2003 |
Popescu G, Auerbach A. Modal gating of NMDA receptors and the shape of their synaptic response. Nature Neuroscience. 6: 476-83. PMID 12679783 DOI: 10.1038/nn1044 |
0.692 |
|
| 2003 |
Auerbach A. A Speculative Model of AChR Gating at the Frog Neuromuscular Junction Science Signaling. 2003: tr2-tr2. DOI: 10.1126/STKE.2003.198.TR2 |
0.507 |
|
| 2002 |
Elenes S, Auerbach A. Desensitization of diliganded mouse muscle nicotinic acetylcholine receptor channels. The Journal of Physiology. 541: 367-83. PMID 12042345 DOI: 10.1113/Jphysiol.2001.016022 |
0.529 |
|
| 2002 |
Auerbach A. Acetylcholine receptors, between closed and open. Novartis Foundation Symposium. 245: 223-34; discussion 2. PMID 12027011 DOI: 10.1002/0470868759.Ch16 |
0.562 |
|
| 2002 |
Cymes GD, Grosman C, Auerbach A. Structure of the transition state of gating in the acetylcholine receptor channel pore: a phi-value analysis. Biochemistry. 41: 5548-55. PMID 11969415 DOI: 10.1021/bi011864f |
0.772 |
|
| 2001 |
Grosman C, Auerbach A. The dissociation of acetylcholine from open nicotinic receptor channels. Proceedings of the National Academy of Sciences of the United States of America. 98: 14102-7. PMID 11717464 DOI: 10.1073/pnas.251402498 |
0.798 |
|
| 2001 |
Zhu Y, Auerbach A. K(+) occupancy of the N-methyl-d-aspartate receptor channel probed by Mg(2+) block. The Journal of General Physiology. 117: 287-98. PMID 11222631 DOI: 10.1085/jgp.117.3.287 |
0.433 |
|
| 2001 |
Zhu Y, Auerbach A. Na(+) occupancy and Mg(2+) block of the n-methyl-d-aspartate receptor channel. The Journal of General Physiology. 117: 275-86. PMID 11222630 DOI: 10.1085/jgp.117.3.275 |
0.441 |
|
| 2001 |
Cymes G, Grosman C, Auerbach A. Surfing the Conformational Wave of Acetylcholine Receptor Channel Gating Microscopy and Microanalysis. 7: 24-25. DOI: 10.1017/S1431927600026192 |
0.745 |
|
| 2000 |
Qin F, Auerbach A, Sachs F. Hidden Markov modeling for single channel kinetics with filtering and correlated noise. Biophysical Journal. 79: 1928-44. PMID 11023898 DOI: 10.1016/S0006-3495(00)76442-3 |
0.664 |
|
| 2000 |
Qin F, Auerbach A, Sachs F. A direct optimization approach to hidden Markov modeling for single channel kinetics. Biophysical Journal. 79: 1915-27. PMID 11023897 DOI: 10.1016/S0006-3495(00)76441-1 |
0.664 |
|
| 2000 |
Grosman C, Salamone FN, Sine SM, Auerbach A. The extracellular linker of muscle acetylcholine receptor channels is a gating control element. The Journal of General Physiology. 116: 327-40. PMID 10962011 DOI: 10.1085/Jgp.116.3.327 |
0.791 |
|
| 2000 |
Grosman C, Auerbach A. Asymmetric and independent contribution of the second transmembrane segment 12' residues to diliganded gating of acetylcholine receptor channels: a single-channel study with choline as the agonist. The Journal of General Physiology. 115: 637-51. PMID 10779320 DOI: 10.1085/jgp.115.5.637 |
0.79 |
|
| 2000 |
Grosman C, Auerbach A. Kinetic, mechanistic, and structural aspects of unliganded gating of acetylcholine receptor channels: a single-channel study of second transmembrane segment 12' mutants. The Journal of General Physiology. 115: 621-35. PMID 10779319 DOI: 10.1085/jgp.115.5.621 |
0.806 |
|
| 2000 |
Grosman C, Zhou M, Auerbach A. Mapping the conformational wave of acetylcholine receptor channel gating. Nature. 403: 773-6. PMID 10693806 DOI: 10.1038/35001586 |
0.777 |
|
| 1999 |
Akk G, Auerbach A. Activation of muscle nicotinic acetylcholine receptor channels by nicotinic and muscarinic agonists. British Journal of Pharmacology. 128: 1467-76. PMID 10602325 DOI: 10.1038/Sj.Bjp.0702941 |
0.721 |
|
| 1999 |
Zhou M, Engel AG, Auerbach A. Serum choline activates mutant acetylcholine receptors that cause slow channel congenital myasthenic syndromes. Proceedings of the National Academy of Sciences of the United States of America. 96: 10466-71. PMID 10468632 DOI: 10.1073/Pnas.96.18.10466 |
0.574 |
|
| 1999 |
Salamone FN, Zhou M, Auerbach A. A re-examination of adult mouse nicotinic acetylcholine receptor channel activation kinetics. The Journal of Physiology. 516: 315-30. PMID 10087333 DOI: 10.1111/J.1469-7793.1999.0315V.X |
0.604 |
|
| 1999 |
Akk G, Zhou M, Auerbach A. A mutational analysis of the acetylcholine receptor channel transmitter binding site. Biophysical Journal. 76: 207-18. PMID 9876135 DOI: 10.1016/S0006-3495(99)77190-0 |
0.75 |
|
| 1998 |
Auerbach A, Akk G. Desensitization of mouse nicotinic acetylcholine receptor channels. A two-gate mechanism. The Journal of General Physiology. 112: 181-97. PMID 9689026 DOI: 10.1085/Jgp.112.2.181 |
0.753 |
|
| 1998 |
Chen J, Auerbach A. A distinct contribution of the delta subunit to acetylcholine receptor channel activation revealed by mutations of the M2 segment. Biophysical Journal. 75: 218-25. PMID 9649381 DOI: 10.1016/S0006-3495(98)77508-3 |
0.535 |
|
| 1997 |
Premkumar LS, Auerbach A. Stoichiometry of recombinant N-methyl-D-aspartate receptor channels inferred from single-channel current patterns. The Journal of General Physiology. 110: 485-502. PMID 9348322 DOI: 10.1085/jgp.110.5.485 |
0.671 |
|
| 1997 |
Wang HL, Auerbach A, Bren N, Ohno K, Engel AG, Sine SM. Mutation in the M1 domain of the acetylcholine receptor alpha subunit decreases the rate of agonist dissociation. The Journal of General Physiology. 109: 757-66. PMID 9222901 DOI: 10.1085/Jgp.109.6.757 |
0.552 |
|
| 1997 |
Qin F, Auerbach A, Sachs F. Maximum likelihood estimation of aggregated Markov processes. Proceedings. Biological Sciences / the Royal Society. 264: 375-83. PMID 9107053 DOI: 10.1098/rspb.1997.0054 |
0.601 |
|
| 1997 |
Premkumar LS, Qin F, Auerbach A. Subconductance states of a mutant NMDA receptor channel kinetics, calcium, and voltage dependence. The Journal of General Physiology. 109: 181-9. PMID 9041447 DOI: 10.1085/jgp.109.2.181 |
0.737 |
|
| 1996 |
Akk G, Sine S, Auerbach A. Binding sites contribute unequally to the gating of mouse nicotinic alpha D200N acetylcholine receptors. The Journal of Physiology. 496: 185-96. PMID 8910207 DOI: 10.1113/Jphysiol.1996.Sp021676 |
0.685 |
|
| 1996 |
Auerbach A, Sigurdson W, Chen J, Akk G. Voltage dependence of mouse acetylcholine receptor gating: different charge movements in di-, mono- and unliganded receptors. The Journal of Physiology. 494: 155-70. PMID 8814613 DOI: 10.1113/Jphysiol.1996.Sp021482 |
0.726 |
|
| 1996 |
Qin F, Auerbach A, Sachs F. Estimating single-channel kinetic parameters from idealized patch-clamp data containing missed events. Biophysical Journal. 70: 264-80. PMID 8770203 DOI: 10.1016/S0006-3495(96)79568-1 |
0.68 |
|
| 1996 |
Akk G, Auerbach A. Inorganic, monovalent cations compete with agonists for the transmitter binding site of nicotinic acetylcholine receptors. Biophysical Journal. 70: 2652-8. PMID 8744302 DOI: 10.1016/S0006-3495(96)79834-X |
0.73 |
|
| 1996 |
Premkumar LS, Auerbach A. Identification of a high affinity divalent cation binding site near the entrance of the NMDA receptor channel. Neuron. 16: 869-80. PMID 8608005 DOI: 10.1016/S0896-6273(00)80107-5 |
0.717 |
|
| 1995 |
Chen J, Zhang Y, Akk G, Sine S, Auerbach A. Activation kinetics of recombinant mouse nicotinic acetylcholine receptors: mutations of alpha-subunit tyrosine 190 affect both binding and gating. Biophysical Journal. 69: 849-59. PMID 8519985 DOI: 10.1016/S0006-3495(95)79959-3 |
0.737 |
|
| 1995 |
Sine SM, Ohno K, Bouzat C, Auerbach A, Milone M, Pruitt JN, Engel AG. Mutation of the acetylcholine receptor alpha subunit causes a slow-channel myasthenic syndrome by enhancing agonist binding affinity. Neuron. 15: 229-39. PMID 7619526 DOI: 10.1016/0896-6273(95)90080-2 |
0.52 |
|
| 1995 |
Zhang Y, Chen J, Auerbach A. Activation of recombinant mouse acetylcholine receptors by acetylcholine, carbamylcholine and tetramethylammonium. The Journal of Physiology. 189-206. PMID 7562635 DOI: 10.1113/jphysiol.1995.sp020802 |
0.527 |
|
| 1995 |
Zhang Y, Auerbach A. Kinetic properties of NMDA receptors in embryonic Xenopus spinal neurons. Journal of Neurophysiology. 74: 153-61. PMID 7472320 DOI: 10.1152/JN.1995.74.1.153 |
0.458 |
|
| 1993 |
Gao J, Chou LW, Auerbach A. The nature of cation-pi binding: interactions between tetramethylammonium ion and benzene in aqueous solution. Biophysical Journal. 65: 43-7. PMID 8369448 DOI: 10.1016/S0006-3495(93)81031-2 |
0.344 |
|
| 1993 |
Auerbach A. A statistical analysis of acetylcholine receptor activation in Xenopus myocytes: stepwise versus concerted models of gating. The Journal of Physiology. 461: 339-78. PMID 8350269 DOI: 10.1113/jphysiol.1993.sp019517 |
0.539 |
|
| 1992 |
Auerbach A. Kinetic behavior of cloned mouse acetylcholine receptors. A semi-autonomous, stepwise model of gating. Biophysical Journal. 62: 72-3. PMID 1600103 DOI: 10.1016/S0006-3495(92)81783-6 |
0.438 |
|
| 1991 |
Auerbach A. Single-channel dose-response studies in single, cell-attached patches. Biophysical Journal. 60: 660-70. PMID 1718468 DOI: 10.1016/S0006-3495(91)82095-1 |
0.428 |
|
| 1991 |
Neil J, Xiang Z, Auerbach A. 29 - List-Oriented Analysis of Single-Channel Data Methods in Neurosciences. 4: 474-490. DOI: 10.1016/B978-0-12-185257-3.50034-3 |
0.334 |
|
| 1990 |
Davidson RM, Tatakis DW, Auerbach AL. Multiple forms of mechanosensitive ion channels in osteoblast-like cells. PflüGers Archiv : European Journal of Physiology. 416: 646-51. PMID 1701046 DOI: 10.1007/BF00370609 |
0.523 |
|
| 1987 |
Auerbach A, Lingle CJ. Activation of the primary kinetic modes of large- and small-conductance cholinergic ion channels in Xenopus myocytes. The Journal of Physiology. 393: 437-66. PMID 2451741 DOI: 10.1113/Jphysiol.1987.Sp016832 |
0.779 |
|
| 1986 |
Auerbach A, Sachs F, Neil J, McGarrigle R. Temperature measurement and control of small volumes: applications for single channel recording. Methods in Enzymology. 124: 190-206. PMID 3713522 DOI: 10.1016/0076-6879(86)24016-1 |
0.679 |
|
| 1986 |
Auerbach A, Lingle CJ. Heterogeneous kinetic properties of acetylcholine receptor channels in Xenopus myocytes. The Journal of Physiology. 378: 119-40. PMID 2432248 DOI: 10.1113/jphysiol.1986.sp016211 |
0.757 |
|
| 1984 |
Auerbach A, Sachs F. Patch clamp studies of single ionic channels. Annual Review of Biophysics and Bioengineering. 13: 269-302. PMID 6331285 DOI: 10.1146/annurev.bb.13.060184.001413 |
0.697 |
|
| 1984 |
Auerbach A, Sachs F. Single-channel currents from acetylcholine receptors in embryonic chick muscle. Kinetic and conductance properties of gaps within bursts. Biophysical Journal. 45: 187-98. PMID 6324902 DOI: 10.1016/S0006-3495(84)84147-8 |
0.688 |
|
| 1984 |
Auerbach A, del Castillo J, Specht PC, Titmus M. Correlation of agonist structure with acetylcholine receptor kinetics: studies on the frog end-plate and on chick embryo muscle. The Journal of Physiology. 343: 551-68. PMID 6315923 DOI: 10.1113/jphysiol.1983.sp014909 |
0.502 |
|
| 1983 |
del Castillo J, Specht P, Auerbach A. Automatic control of potential and agonist-induced current across the endplate membrane by drug electrophoresis. Journal of Neuroscience Research. 8: 35-48. PMID 6983588 DOI: 10.1002/JNR.490080107 |
0.311 |
|
| 1983 |
Sachs F, Auerbach A. Single-channel electrophysiology: use of the patch clamp. Methods in Enzymology. 103: 147-76. PMID 6321886 DOI: 10.1016/S0076-6879(83)03011-6 |
0.705 |
|
| 1983 |
Auerbach A, Sachs F. Flickering of a nicotinic ion channel to a subconductance state. Biophysical Journal. 42: 1-10. PMID 6301574 DOI: 10.1016/S0006-3495(83)84362-8 |
0.721 |
|
| 1983 |
Lingle C, Auerbach A. Comparison of excitatory currents activated by different transmitters on crustacean muscle. II. Glutamate-activated currents and comparison with acetylcholine currents present on the same muscle. The Journal of General Physiology. 81: 571-88. PMID 6133908 DOI: 10.1085/Jgp.81.4.571 |
0.719 |
|
| 1983 |
Lingle C, Auerbach A. Comparison of excitatory currents activated by different transmitters on crustacean muscle. I. Acetylcholine-activated channels. The Journal of General Physiology. 81: 547-69. PMID 6133907 DOI: 10.1085/Jgp.81.4.547 |
0.744 |
|
| 1981 |
Auerbach A, Barker DL. [(3)H]Choline uptake and metabolism in nonsynaptic regions of a crustacean sensory nerve. Journal of Neurochemistry. 36: 1648-58. PMID 7241126 |
0.466 |
|
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