Jiang-Fan Chen - Publications

Boston University, Boston, MA, United States 
Neuroscience Biology

164 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Zhong DJ, Zhang Y, Zhang S, Ge YY, Tong M, Feng Y, You F, Zhao X, Wang K, Zhang L, Liu X, Chen JF. Adenosine A receptor antagonism protects against hyperoxia-induced retinal vascular loss via cellular proliferation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21842. PMID 34418159 DOI: 10.1096/fj.202100414RR  1
2021 He Y, Huang L, Wang K, Pan X, Cai Q, Zhang F, Yang J, Fang G, Zhao X, You F, Feng Y, Li Y, Chen JF. α-Synuclein Selectively Impairs Motor Sequence Learning and Value Sensitivity: Reversal by the Adenosine A2A Receptor Antagonists. Cerebral Cortex (New York, N.Y. : 1991). PMID 34339491 DOI: 10.1093/cercor/bhab244  1
2021 Augusto E, Gonçalves FQ, Real JE, Silva HB, Pochmann D, Silva TS, Matos M, Gonçalves N, Tomé ÂR, Chen JF, Canas PM, Cunha RA. Increased ATP release and CD73-mediated adenosine A receptor activation mediate convulsion-associated neuronal damage and hippocampal dysfunction. Neurobiology of Disease. 105441. PMID 34224862 DOI: 10.1016/j.nbd.2021.105441  1
2020 Ren X, Chen JF. Caffeine and Parkinson's Disease: Multiple Benefits and Emerging Mechanisms. Frontiers in Neuroscience. 14: 602697. PMID 33390888 DOI: 10.3389/fnins.2020.602697  0.01
2020 Chen JF, Schwarzschild MA. Do caffeine and more selective adenosine A receptor antagonists protect against dopaminergic neurodegeneration in Parkinson's disease? Parkinsonism & Related Disorders. 45-53. PMID 33349580 DOI: 10.1016/j.parkreldis.2020.10.024  0.01
2020 Xu T, Wang J, Hu B, Zhang G, Zhou W, Zheng M, Shen B, Sun B, Zhang Y, Chen Y, Yu J, Liang M, Pan J, Chen C, Chen H, ... ... Chen JF, et al. Identification of the RNase-binding site of SARS-CoV-2 RNA for anchor primer-PCR detection of viral loading in 306 COVID-19 patients. Briefings in Bioinformatics. PMID 32935831 DOI: 10.1093/bib/bbaa193  0.01
2020 Zhang L, Zhou Y, Liu C, Zheng W, Yao Z, Wang Q, Jin Y, Zhang S, Chen W, Chen JF. Adenosine A receptor blockade improves neuroprosthetic learning by volitional control of population calcium signal in M1 cortical neurons. Neuropharmacology. 108250. PMID 32726599 DOI: 10.1016/j.neuropharm.2020.108250  1
2020 Zeng XJ, Li P, Ning YL, Zhao Y, Peng Y, Yang N, Xu YW, Chen JF, Zhou YG. A R inhibition in alleviating spatial recognition memory impairment after TBI is associated with improvement in autophagic flux in RSC. Journal of Cellular and Molecular Medicine. PMID 32394486 DOI: 10.1111/Jcmm.15361  1
2020 Chen JF, Cunha RA. The belated US FDA approval of the adenosine A receptor antagonist istradefylline for treatment of Parkinson's disease. Purinergic Signalling. PMID 32236790 DOI: 10.1007/s11302-020-09694-2  1
2020 Li Y, Ruan Y, He Y, Cai Q, Pan X, Zhang Y, Liu C, Pu Z, Yang J, Chen M, Huang L, Zhou J, Chen JF. Striatopallidal adenosine A receptors in the nucleus accumbens confer motivational control of goal-directed behavior. Neuropharmacology. 108010. PMID 32061899 DOI: 10.1016/j.neuropharm.2020.108010  1
2019 He Y, Li Y, Pu Z, Chen M, Gao Y, Chen L, Ruan Y, Pan X, Zhou Y, Ge Y, Zhou J, Zheng W, Huang Z, Li Z, Chen JF. Striatopallidal Pathway Distinctly Modulates Goal-Directed Valuation and Acquisition of Instrumental Behavior via Striatopallidal Output Projections. Cerebral Cortex (New York, N.Y. : 1991). PMID 31690946 DOI: 10.1093/Cercor/Bhz172  1
2019 Hong SI, Kang S, Chen JF, Choi DS. Indirect medium spiny neurons in the dorsomedial striatum regulate ethanol-containing conditioned reward seeking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31315945 DOI: 10.1523/Jneurosci.0876-19.2019  0.01
2019 Tang Y, Yin HY, Illes P, Burnstock G, Chen JF. From the Sino-German collaboration on purines to the Chinese Purine Club. Purinergic Signalling. PMID 31243615 DOI: 10.1007/s11302-019-09665-2  0.01
2019 Chen Y, Zhang ZX, Zheng LP, Wang L, Liu YF, Yin WY, Chen YY, Wang XS, Hou ST, Chen JF, Zheng RY. The adenosine A receptor antagonist SCH58261 reduces macrophage/microglia activation and protects against experimental autoimmune encephalomyelitis in mice. Neurochemistry International. 104490. PMID 31226280 DOI: 10.1016/J.Neuint.2019.104490  0.01
2019 Korkutata M, Saitoh T, Cherasse Y, Ioka S, Duo F, Qin R, Murakoshi N, Fujii S, Zhou X, Sugiyama F, Chen JF, Kumagai H, Nagase H, Lazarus M. Corrigendum to "Enhancing endogenous adenosine A receptor signaling induces slow-wave sleep without affecting body temperature and cardiovascular function" [Neuropharmacology 144 (2019) 122-132]. Neuropharmacology. PMID 31101360 DOI: 10.1016/J.Neuropharm.2019.04.027  1
2019 Zhou J, Wu B, Lin X, Dai Y, Li T, Zheng W, Guo W, Vakal S, Chen X, Chen JF. Accumbal Adenosine A Receptors Enhance Cognitive Flexibility by Facilitating Strategy Shifting. Frontiers in Cellular Neuroscience. 13: 130. PMID 31031594 DOI: 10.3389/fncel.2019.00130  1
2019 Zhou Y, Zeng X, Li G, Yang Q, Xu J, Zhang M, Mao X, Cao Y, Wang L, Xu Y, Wang Y, Zhang Y, Xu Z, Wu C, Chen JF, et al. Inactivation of endothelial adenosine receptor 2A protects mice from cerebral ischemia-induced brain injury. British Journal of Pharmacology. PMID 30931525 DOI: 10.1111/bph.14673  1
2018 Canas PM, Porciúncula LO, Simões AP, Augusto E, Silva HB, Machado NJ, Gonçalves N, Alfaro TM, Gonçalves FQ, Araújo IM, Real JI, Coelho JE, Andrade GM, Almeida RD, Chen JF, et al. Neuronal Adenosine A2A Receptors Are Critical Mediators of Neurodegeneration Triggered by Convulsions. Eneuro. 5. PMID 30627646 DOI: 10.1523/ENEURO.0385-18.2018  1
2018 Li HM, Jang JH, Jung JS, Shin J, Park CO, Kim YJ, Ahn WG, Nam JS, Hong CW, Lee J, Jung YJ, Chen JF, Ravid K, Lee HT, Huh WK, et al. G2A Protects Mice against Sepsis by Modulating Kupffer Cell Activation: Cooperativity with Adenosine Receptor 2b. Journal of Immunology (Baltimore, Md. : 1950). PMID 30530591 DOI: 10.4049/Jimmunol.1700783  0.01
2018 Ning YL, Yang N, Chen X, Tian HK, Zhao ZA, Zhang XZ, Liu D, Li P, Zhao Y, Peng Y, Wang ZG, Chen JF, Zhou YG. Caffeine attenuates brain injury but increases mortality induced by high-intensity blast wave exposure. Toxicology Letters. PMID 30423366 DOI: 10.1016/J.Toxlet.2018.11.004  1
2018 Korkutata M, Saitoh T, Cherasse Y, Ioka S, Duo F, Qin R, Murakoshi N, Fujii S, Zhou X, Sugiyama F, Chen JF, Kumagai H, Nagase H, Lazarus M. Enhancing endogenous adenosine A receptor signaling induces slow-wave sleep without affecting body temperature and cardiovascular function. Neuropharmacology. PMID 30336152 DOI: 10.1016/J.Neuropharm.2018.10.022  1
2018 Tian J, Yan Y, Xi W, Zhou R, Lou H, Duan S, Chen JF, Zhang B. Optogenetic Stimulation of GABAergic Neurons in the Globus Pallidus Produces Hyperkinesia. Frontiers in Behavioral Neuroscience. 12: 185. PMID 30210317 DOI: 10.3389/Fnbeh.2018.00185  1
2018 Zhou R, Zhang S, Gu X, Ge Y, Zhong D, Zhou Y, Tang L, Liu XL, Chen JF. Adenosine A receptor antagonists act at the hyperoxic phase to confer protection against retinopathy. Molecular Medicine (Cambridge, Mass.). 24: 41. PMID 30134834 DOI: 10.1186/s10020-018-0038-1  1
2018 Luan Y, Ren X, Zheng W, Zeng Z, Guo Y, Hou Z, Guo W, Chen X, Li F, Chen JF. Chronic Caffeine Treatment Protects Against α-Synucleinopathy by Reestablishing Autophagy Activity in the Mouse Striatum. Frontiers in Neuroscience. 12: 301. PMID 29770111 DOI: 10.3389/Fnins.2018.00301  1
2018 Li Y, Pan X, He Y, Ruan Y, Huang L, Zhou Y, Hou Z, He C, Wang Z, Zhang X, Chen JF. Pharmacological Blockade of Adenosine A but Not A Receptors Enhances Goal-Directed Valuation in Satiety-Based Instrumental Behavior. Frontiers in Pharmacology. 9: 393. PMID 29740319 DOI: 10.3389/Fphar.2018.00393  1
2018 Luo YJ, Li YD, Wang L, Yang SR, Yuan XS, Wang J, Cherasse Y, Lazarus M, Chen JF, Qu WM, Huang ZL. Nucleus accumbens controls wakefulness by a subpopulation of neurons expressing dopamine D receptors. Nature Communications. 9: 1576. PMID 29679009 DOI: 10.1038/S41467-018-03889-3  1
2018 Zheng W, Zhou J, Luan Y, Yang J, Ge Y, Wang M, Wu B, Wu Z, Chen X, Li F, Li Z, Vakal S, Guo W, Chen JF. Spatiotemporal Control of GPR37 Signaling and Its Behavioral Effects by Optogenetics. Frontiers in Molecular Neuroscience. 11: 95. PMID 29643766 DOI: 10.3389/Fnmol.2018.00095  1
2018 Zeng XJ, Li P, Ning YL, Zhao Y, Peng Y, Yang N, Zhao ZA, Chen JF, Zhou YG. Impaired autophagic flux is associated with the severity of trauma and the role of AR in brain cells after traumatic brain injury. Cell Death & Disease. 9: 252. PMID 29449536 DOI: 10.1038/S41419-018-0316-4  1
2017 Fang T, Dong H, Xu XH, Yuan XS, Chen ZK, Chen JF, Qu WM, Huang ZL. Adenosine A2A receptor mediates hypnotic effects of ethanol in mice. Scientific Reports. 7: 12678. PMID 28978989 DOI: 10.1038/S41598-017-12689-6  1
2017 Li Z, Chen X, Wang T, Gao Y, Li F, Chen L, Xue J, He Y, Li Y, Guo W, Zheng W, Zhang L, Ye F, Ren X, Feng Y, ... Chen JF, et al. The Corticostriatal Adenosine A2A Receptor Controls Maintenance and Retrieval of Spatial Working Memory. Biological Psychiatry. PMID 28941549 DOI: 10.1016/J.Biopsych.2017.07.017  1
2017 Liu Z, Yan S, Wang J, Xu Y, Wang Y, Zhang S, Xu X, Yang Q, Zeng X, Zhou Y, Gu X, Lu S, Fu Z, Fulton DJ, Weintraub NL, ... ... Chen JF, et al. Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis. Nature Communications. 8: 584. PMID 28928465 DOI: 10.1038/S41467-017-00551-2  1
2017 Lazarus M, Chen JF, Huang ZL, Urade Y, Fredholm BB. Adenosine and Sleep. Handbook of Experimental Pharmacology. PMID 28646346 DOI: 10.1007/164_2017_36  1
2017 Zhao ZA, Li P, Ye SY, Ning YL, Wang H, Peng Y, Yang N, Zhao Y, Zhang ZH, Chen JF, Zhou YG. Perivascular AQP4 dysregulation in the hippocampal CA1 area after traumatic brain injury is alleviated by adenosine A2A receptor inactivation. Scientific Reports. 7: 2254. PMID 28533515 DOI: 10.1038/S41598-017-02505-6  1
2017 Zhang S, Zhou R, Li B, Li H, Wang Y, Gu X, Tang L, Wang C, Zhong D, Ge Y, Huo Y, Lin J, Liu XL, Chen JF. Caffeine preferentially protects against oxygen-induced retinopathy. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28420694 DOI: 10.1096/fj.201601285R  1
2017 Dai QX, Geng WJ, Zhuang XX, Wang HF, Mo YC, Xin H, Chen JF, Wang JL. Electroacupuncture-induced neuroprotection against focal cerebral ischemia in the rat is mediated by adenosine A1 receptors. Neural Regeneration Research. 12: 228-234. PMID 28400804 DOI: 10.4103/1673-5374.200806  0.01
2017 Zhao ZA, Ning YL, Li P, Yang N, Peng Y, Xiong RP, Zhao Y, Liu D, Zeng XJ, Chen JF, Zhou YG. Widespread hyperphosphorylated tau in the working memory circuit early after cortical impact injury of brain (Original study). Behavioural Brain Research. PMID 28163095 DOI: 10.1016/J.Bbr.2017.02.002  1
2017 Zhang BJ, Huang ZL, Chen JF, Urade Y, Qu WM. Adenosine A2A receptor deficiency attenuates the somnogenic effect of prostaglandin D2 in mice. Acta Pharmacologica Sinica. PMID 28112177 DOI: 10.1038/Aps.2016.140  1
2017 Chen JF, Zhang S, Zhou R, Lin Z, Cai X, Lin J, Huo Y, Liu X. Adenosine receptors and caffeine in retinopathy of prematurity. Molecular Aspects of Medicine. PMID 28088487 DOI: 10.1016/j.mam.2017.01.001  1
2016 He Y, Li Y, Chen M, Pu Z, Zhang F, Chen L, Ruan Y, Pan X, He C, Chen X, Li Z, Chen JF. Habit Formation after Random Interval Training Is Associated with Increased Adenosine A2A Receptor and Dopamine D2 Receptor Heterodimers in the Striatum. Frontiers in Molecular Neuroscience. 9: 151. PMID 28082865 DOI: 10.3389/fnmol.2016.00151  1
2016 Truong LD, Trostel J, McMahan R, Chen JF, Garcia GE. Macrophage A2A Adenosine Receptors Are Essential to Protect from Progressive Kidney Injury. The American Journal of Pathology. PMID 27520357 DOI: 10.1016/J.Ajpath.2016.06.017  0.01
2016 Labadorf A, Hoss AG, Lagomarsino V, Latourelle JC, Hadzi TC, Bregu J, MacDonald ME, Gusella JF, Chen JF, Akbarian S, Weng Z, Myers RH. Correction: RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression. Plos One. 11: e0160295. PMID 27454300 DOI: 10.1371/journal.pone.0160295  1
2016 Hu Q, Ren X, Liu Y, Li Z, Zhang L, Chen X, He C, Chen JF. Aberrant adenosine A2A receptor signaling contributes to neurodegeneration and cognitive impairments in a mouse model of synucleinopathy. Experimental Neurology. PMID 27342081 DOI: 10.1016/J.Expneurol.2016.05.040  1
2015 Zhang S, Li H, Li B, Zhong D, Gu X, Tang L, Wang Y, Wang C, Zhou R, Li Y, He Y, Chen M, Huo Y, Liu XL, Chen JF. Adenosine A1 Receptors Selectively Modulate Oxygen-Induced Retinopathy at the Hyperoxic and Hypoxic Phases by Distinct Cellular Mechanisms. Investigative Ophthalmology & Visual Science. 56: 8108-8119. PMID 26720463 DOI: 10.1167/iovs.15-17202  1
2015 Shang P, He ZY, Chen JF, Huang SY, Liu BH, Liu HX, Wang XT. Absence of the Adenosine A2A Receptor Confers Pulmonary Arterial Hypertension Through RhoA/ROCK Signaling Pathway in Mice. Journal of Cardiovascular Pharmacology. 66: 569-75. PMID 26647014 DOI: 10.1097/Fjc.0000000000000305  0.01
2015 Labadorf A, Hoss AG, Lagomarsino V, Latourelle JC, Hadzi TC, Bregu J, MacDonald ME, Gusella JF, Chen JF, Akbarian S, Weng Z, Myers RH. RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression. Plos One. 10: e0143563. PMID 26636579 DOI: 10.1371/Journal.Pone.0143563  1
2015 Dong X, Tsuji J, Labadorf A, Roussos P, Chen JF, Myers RH, Akbarian S, Weng Z. The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington's Disease. Plos One. 10: e0144398. PMID 26636336 DOI: 10.1371/Journal.Pone.0144398  1
2015 Yin D, Liu YY, Wang TX, Hu ZZ, Qu WM, Chen JF, Cheng NN, Huang ZL. Paeoniflorin exerts analgesic and hypnotic effects via adenosine A1 receptors in a mouse neuropathic pain model. Psychopharmacology. PMID 26514553 DOI: 10.1007/S00213-015-4108-6  1
2015 Chen C, Sun Y, Luo YJ, Zhao X, Chen JF, Yanagawa Y, Qu W, Huang ZL. Paeoniflorin Promotes Non-rapid Eye Movement Sleep via Adenosine A1 Receptors. The Journal of Pharmacology and Experimental Therapeutics. PMID 26491061 DOI: 10.1124/Jpet.115.227819  1
2015 Li Y, He Y, Chen M, Pu Z, Chen L, Li P, Li B, Li H, Huang Z, Li Z, Chen JF. Opotogenetic Activation of Adenosine A2A Receptor Signaling in the Dorsomedial Striatopallidal Neurons Suppresses Goal-Directed Behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26216520 DOI: 10.1038/Npp.2015.227  1
2015 Kaster MP, Machado NJ, Silva HB, Nunes A, Ardais AP, Santana M, Baqi Y, Müller CE, Rodrigues AL, Porciúncula LO, Chen JF, Tomé ÂR, Agostinho P, Canas PM, Cunha RA. Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress. Proceedings of the National Academy of Sciences of the United States of America. 112: 7833-8. PMID 26056314 DOI: 10.1073/Pnas.1423088112  1
2015 Li W, Silva HB, Real J, Wang YM, Rial D, Li P, Payen MP, Zhou Y, Muller CE, Tomé AR, Cunha RA, Chen JF. Inactivation of adenosine A2A receptors reverses working memory deficits at early stages of Huntington's disease models. Neurobiology of Disease. 79: 70-80. PMID 25892655 DOI: 10.1016/J.Nbd.2015.03.030  1
2015 Hoss AG, Labadorf A, Latourelle JC, Kartha VK, Hadzi TC, Gusella JF, MacDonald ME, Chen JF, Akbarian S, Weng Z, Vonsattel JP, Myers RH. miR-10b-5p expression in Huntington's disease brain relates to age of onset and the extent of striatal involvement. Bmc Medical Genomics. 8: 10. PMID 25889241 DOI: 10.1186/S12920-015-0083-3  1
2015 Matos M, Shen HY, Augusto E, Wang Y, Wei CJ, Wang YT, Agostinho P, Boison D, Cunha RA, Chen JF. Deletion of Adenosine A2A Receptors from Astrocytes Disrupts Glutamate Homeostasis Leading to Psychomotor and Cognitive Impairment: Relevance to Schizophrenia. Biological Psychiatry. PMID 25869810 DOI: 10.1016/J.Biopsych.2015.02.026  1
2015 Li QH, Xie WX, Li XP, Huang KT, Du ZH, Cong WJ, Zhou LH, Ye TS, Chen JF. Adenosine A2A Receptors Mediate Anti-Inflammatory Effects of Electroacupuncture on Synovitis in Mice with Collagen-Induced Arthritis. Evidence-Based Complementary and Alternative Medicine : Ecam. 2015: 809560. PMID 25784951 DOI: 10.1155/2015/809560  0.01
2015 Yan T, Xiong W, Huang F, Zheng F, Ying H, Chen JF, Qu J, Zhou X. Daily Injection But Not Continuous Infusion of Apomorphine Inhibits Form-Deprivation Myopia in Mice. Investigative Ophthalmology & Visual Science. 56: 2475-85. PMID 25744977 DOI: 10.1167/Iovs.13-12361  0.01
2015 Bai G, Cheung I, Shulha HP, Coelho JE, Li P, Dong X, Jakovcevski M, Wang Y, Grigorenko A, Jiang Y, Hoss A, Patel K, Zheng M, Rogaev E, Myers RH, ... ... Chen JF, et al. Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brains. Human Molecular Genetics. 24: 1441-56. PMID 25480889 DOI: 10.1093/Hmg/Ddu561  1
2014 Chen JF. Adenosine receptor control of cognition in normal and disease. International Review of Neurobiology. 119: 257-307. PMID 25175970 DOI: 10.1016/B978-0-12-801022-8.00012-X  0.01
2014 Chen JF, Lee CF, Chern Y. Adenosine receptor neurobiology: overview. International Review of Neurobiology. 119: 1-49. PMID 25175959 DOI: 10.1016/B978-0-12-801022-8.00001-5  1
2014 Huang F, Yan T, Shi F, An J, Xie R, Zheng F, Li Y, Chen J, Qu J, Zhou X. Activation of dopamine D2 receptor is critical for the development of form-deprivation myopia in the C57BL/6 mouse. Investigative Ophthalmology & Visual Science. 55: 5537-44. PMID 25097246 DOI: 10.1167/Iovs.13-13211  0.01
2014 Wang T, Xi NN, Chen Y, Shang XF, Hu Q, Chen JF, Zheng RY. Chronic caffeine treatment protects against experimental autoimmune encephalomyelitis in mice: therapeutic window and receptor subtype mechanism. Neuropharmacology. 86: 203-11. PMID 25019206 DOI: 10.1016/J.Neuropharm.2014.06.029  1
2014 Hoss AG, Kartha VK, Dong X, Latourelle JC, Dumitriu A, Hadzi TC, Macdonald ME, Gusella JF, Akbarian S, Chen JF, Weng Z, Myers RH. MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis. Plos Genetics. 10: e1004188. PMID 24586208 DOI: 10.1371/Journal.Pgen.1004188  1
2014 Wei CJ, Augusto E, Gomes CA, Singer P, Wang Y, Boison D, Cunha RA, Yee BK, Chen JF. Regulation of fear responses by striatal and extrastriatal adenosine A2A receptors in forebrain. Biological Psychiatry. 75: 855-63. PMID 23820821 DOI: 10.1016/J.Biopsych.2013.05.003  1
2013 Shen HY, Canas PM, Garcia-Sanz P, Lan JQ, Boison D, Moratalla R, Cunha RA, Chen JF. Adenosine Aâ‚‚A receptors in striatal glutamatergic terminals and GABAergic neurons oppositely modulate psychostimulant action and DARPP-32 phosphorylation. Plos One. 8: e80902. PMID 24312250 DOI: 10.1371/Journal.Pone.0080902  1
2013 Matos M, Augusto E, Agostinho P, Cunha RA, Chen JF. Antagonistic interaction between adenosine A2A receptors and Na+/K+-ATPase-α2 controlling glutamate uptake in astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 18492-502. PMID 24259572 DOI: 10.1523/Jneurosci.1828-13.2013  1
2013 Tao Y, Pan M, Liu S, Fang F, Lu R, Lu C, Zheng M, An J, Xu H, Zhao F, Chen JF, Qu J, Zhou X. cAMP level modulates scleral collagen remodeling, a critical step in the development of myopia. Plos One. 8: e71441. PMID 23951163 DOI: 10.1371/Journal.Pone.0071441  0.01
2013 Ning YL, Yang N, Chen X, Xiong RP, Zhang XZ, Li P, Zhao Y, Chen XY, Liu P, Peng Y, Wang ZG, Chen JF, Zhou YG. Adenosine A2A receptor deficiency alleviates blast-induced cognitive dysfunction. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1789-98. PMID 23921902 DOI: 10.1038/Jcbfm.2013.127  1
2013 Augusto E, Matos M, Sévigny J, El-Tayeb A, Bynoe MS, Müller CE, Cunha RA, Chen JF. Ecto-5'-nucleotidase (CD73)-mediated formation of adenosine is critical for the striatal adenosine A2A receptor functions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 11390-9. PMID 23843511 DOI: 10.1523/Jneurosci.5817-12.2013  1
2013 Chen JF, Eltzschig HK, Fredholm BB. Adenosine receptors as drug targets--what are the challenges? Nature Reviews. Drug Discovery. 12: 265-86. PMID 23535933 DOI: 10.1038/Nrd3955  1
2013 Dai SS, Wang H, Yang N, An JH, Li W, Ning YL, Zhu PF, Chen JF, Zhou YG. Plasma glutamate-modulated interaction of A2AR and mGluR5 on BMDCs aggravates traumatic brain injury-induced acute lung injury. The Journal of Experimental Medicine. 210: 839-51. PMID 23478188 DOI: 10.1084/Jem.20122196  1
2013 Lazarus M, Chen JF, Urade Y, Huang ZL. Role of the basal ganglia in the control of sleep and wakefulness. Current Opinion in Neurobiology. 23: 780-5. PMID 23465424 DOI: 10.1016/J.Conb.2013.02.001  1
2013 Chia JS, McRae JL, Thomas HE, Fynch S, Elkerbout L, Hill P, Murray-Segal L, Robson SC, Chen JF, d'Apice AJ, Cowan PJ, Dwyer KM. The protective effects of CD39 overexpression in multiple low-dose streptozotocin-induced diabetes in mice. Diabetes. 62: 2026-35. PMID 23364452 DOI: 10.2337/db12-0625  1
2013 Wills AM, Eberly S, Tennis M, Lang AE, Messing S, Togasaki D, Tanner CM, Kamp C, Chen JF, Oakes D, McDermott MP, Schwarzschild MA. Caffeine consumption and risk of dyskinesia in CALM-PD. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 380-3. PMID 23339054 DOI: 10.1002/Mds.25319  1
2013 Singer P, Wei CJ, Chen JF, Boison D, Yee BK. Deletion of striatal adenosine A(2A) receptor spares latent inhibition and prepulse inhibition but impairs active avoidance learning. Behavioural Brain Research. 242: 54-61. PMID 23276608 DOI: 10.1016/J.Bbr.2012.12.024  1
2012 Liu S, Chen JF. Strategies for therapeutic hypometabothermia. Journal of Experimental Stroke & Translational Medicine. 5: 31-42. PMID 24179563 DOI: 10.4172/1939-067X.1000139  0.01
2012 Shulha HP, Crisci JL, Reshetov D, Tushir JS, Cheung I, Bharadwaj R, Chou HJ, Houston IB, Peter CJ, Mitchell AC, Yao WD, Myers RH, Chen JF, Preuss TM, Rogaev EI, et al. Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. Plos Biology. 10: e1001427. PMID 23185133 DOI: 10.1371/Journal.Pbio.1001427  1
2012 Lazarus M, Huang ZL, Lu J, Urade Y, Chen JF. How do the basal ganglia regulate sleep-wake behavior? Trends in Neurosciences. 35: 723-32. PMID 22858523 DOI: 10.1016/J.Tins.2012.07.001  1
2012 Shen HY, Singer P, Lytle N, Wei CJ, Lan JQ, Williams-Karnesky RL, Chen JF, Yee BK, Boison D. Adenosine augmentation ameliorates psychotic and cognitive endophenotypes of schizophrenia. The Journal of Clinical Investigation. 122: 2567-77. PMID 22706302 DOI: 10.1172/Jci62378  1
2012 Yao SQ, Li ZZ, Huang QY, Li F, Wang ZW, Augusto E, He JC, Wang XT, Chen JF, Zheng RY. Genetic inactivation of the adenosine A(2A) receptor exacerbates brain damage in mice with experimental autoimmune encephalomyelitis. Journal of Neurochemistry. 123: 100-12. PMID 22639925 DOI: 10.1111/J.1471-4159.2012.07807.X  1
2012 Mills JH, Kim DG, Krenz A, Chen JF, Bynoe MS. A2A adenosine receptor signaling in lymphocytes and the central nervous system regulates inflammation during experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 188: 5713-22. PMID 22529293 DOI: 10.4049/Jimmunol.1200545  0.01
2012 Matos M, Augusto E, Santos-Rodrigues AD, Schwarzschild MA, Chen JF, Cunha RA, Agostinho P. Adenosine A2A receptors modulate glutamate uptake in cultured astrocytes and gliosomes. Glia. 60: 702-16. PMID 22298379 DOI: 10.1002/Glia.22290  1
2011 Dong F, Zhi Z, Pan M, Xie R, Qin X, Lu R, Mao X, Chen JF, Willcox MD, Qu J, Zhou X. Inhibition of experimental myopia by a dopamine agonist: different effectiveness between form deprivation and hyperopic defocus in guinea pigs. Molecular Vision. 17: 2824-34. PMID 22128230  0.01
2011 Lazarus M, Shen HY, Cherasse Y, Qu WM, Huang ZL, Bass CE, Winsky-Sommerer R, Semba K, Fredholm BB, Boison D, Hayaishi O, Urade Y, Chen JF. Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10067-75. PMID 21734299 DOI: 10.1523/Jneurosci.6730-10.2011  1
2011 Huang NK, Lin JH, Lin JT, Lin CI, Liu EM, Lin CJ, Chen WP, Shen YC, Chen HM, Chen JB, Lai HL, Yang CW, Chiang MC, Wu YS, Chang C, ... Chen JF, et al. A new drug design targeting the adenosinergic system for Huntington's disease. Plos One. 6: e20934. PMID 21713039 DOI: 10.1371/Journal.Pone.0020934  1
2011 Wei CJ, Singer P, Coelho J, Boison D, Feldon J, Yee BK, Chen JF. Selective inactivation of adenosine A(2A) receptors in striatal neurons enhances working memory and reversal learning. Learning & Memory (Cold Spring Harbor, N.Y.). 18: 459-74. PMID 21693634 DOI: 10.1101/Lm.2136011  1
2011 Garcia GE, Truong LD, Chen JF, Johnson RJ, Feng L. Adenosine A(2A) receptor activation prevents progressive kidney fibrosis in a model of immune-associated chronic inflammation. Kidney International. 80: 378-88. PMID 21508927 DOI: 10.1038/ki.2011.101  1
2011 Wei CJ, Li W, Chen JF. Normal and abnormal functions of adenosine receptors in the central nervous system revealed by genetic knockout studies. Biochimica Et Biophysica Acta. 1808: 1358-79. PMID 21185258 DOI: 10.1016/J.Bbamem.2010.12.018  1
2011 Chen JF, Chern Y. Impacts of methylxanthines and adenosine receptors on neurodegeneration: Human and experimental studies Handbook of Experimental Pharmacology. 200: 267-310. PMID 20859800 DOI: 10.1007/978-3-642-13443-2_10  1
2011 Xiao D, Cassin JJ, Healy B, Burdett TC, Chen JF, Fredholm BB, Schwarzschild MA. Deletion of adenosine A₁ or A(â‚‚A) receptors reduces L-3,4-dihydroxyphenylalanine-induced dyskinesia in a model of Parkinson's disease. Brain Research. 1367: 310-8. PMID 20828543 DOI: 10.1016/J.Brainres.2010.08.099  1
2010 Liu XL, Zhou R, Pan QQ, Jia XL, Gao WN, Wu J, Lin J, Chen JF. Genetic inactivation of the adenosine A2A receptor attenuates pathologic but not developmental angiogenesis in the mouse retina. Investigative Ophthalmology & Visual Science. 51: 6625-32. PMID 20610844 DOI: 10.1167/iovs.09-4900  1
2010 Sturgess JE, Ting-A-Kee RA, Podbielski D, Sellings LH, Chen JF, van der Kooy D. Adenosine A1 and A2A receptors are not upstream of caffeine's dopamine D2 receptor-dependent aversive effects and dopamine-independent rewarding effects. The European Journal of Neuroscience. 32: 143-54. PMID 20576036 DOI: 10.1111/J.1460-9568.2010.07247.X  1
2010 Goldman N, Chen M, Fujita T, Xu Q, Peng W, Liu W, Jensen TK, Pei Y, Wang F, Han X, Chen JF, Schnermann J, Takano T, Bekar L, Tieu K, et al. Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture. Nature Neuroscience. 13: 883-8. PMID 20512135 DOI: 10.1038/Nn.2562  1
2010 Dai SS, Zhou YG, Li W, An JH, Li P, Yang N, Chen XY, Xiong RP, Liu P, Zhao Y, Shen HY, Zhu PF, Chen JF. Local glutamate level dictates adenosine A2A receptor regulation of neuroinflammation and traumatic brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5802-10. PMID 20410132 DOI: 10.1523/Jneurosci.0268-10.2010  1
2010 Dai SS, Li W, An JH, Wang H, Yang N, Chen XY, Zhao Y, Li P, Liu P, Chen JF, Zhou YG. Adenosine A2A receptors in both bone marrow cells and non-bone marrow cells contribute to traumatic brain injury. Journal of Neurochemistry. 113: 1536-44. PMID 20367749 DOI: 10.1111/J.1471-4159.2010.06716.X  1
2010 Chen JF, Yu L, Shen HY, He JC, Wang X, Zheng R. What knock-out animals tell us about the effects of caffeine. Journal of Alzheimer's Disease : Jad. 20: S17-24. PMID 20182058 DOI: 10.3233/Jad-2010-1403  1
2010 Yang A, Mucsi AD, Desrosiers MD, Chen JF, Schnermann JB, Blackburn MR, Shi Y. Adenosine mediated desensitization of cAMP signaling enhances T-cell responses. European Journal of Immunology. 40: 449-59. PMID 19950175 DOI: 10.1002/Eji.200939586  0.01
2010 Sehba FA, Flores R, Muller A, Friedrich V, Chen JF, Britz GW, Winn HR, Bederson JB. Adenosine A(2A) receptors in early ischemic vascular injury after subarachnoid hemorrhage. Laboratory investigation. Journal of Neurosurgery. 113: 826-34. PMID 19895201 DOI: 10.3171/2009.9.JNS09802  1
2010 Chen GQ, Chen YY, Wang XS, Wu SZ, Yang HM, Xu HQ, He JC, Wang XT, Chen JF, Zheng RY. Chronic caffeine treatment attenuates experimental autoimmune encephalomyelitis induced by guinea pig spinal cord homogenates in Wistar rats. Brain Research. 1309: 116-25. PMID 19879252 DOI: 10.1016/j.brainres.2009.10.054  1
2010 Shen HY, Zhao Y, Chen XY, Xiong RP, Lu JL, Chen JF, Chen LY, Zhou YG. Differential alteration of heat shock protein 90 in mice modifies glucocorticoid receptor function and susceptibility to trauma. Journal of Neurotrauma. 27: 373-81. PMID 19845467 DOI: 10.1089/neu.2009.0926  1
2010 Boison D, Chen JF, Fredholm BB. Adenosine signaling and function in glial cells. Cell Death and Differentiation. 17: 1071-82. PMID 19763139 DOI: 10.1038/Cdd.2009.131  1
2010 Lazarus M, Cherasse Y, Hiasa M, Chen J, Urade Y, Hayaishi O. The role of extracellular adenosine in the basal ganglia for sleep-wake regulation Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.264  1
2009 Shen HY, Chen JF. Adenosine A(2A) receptors in psychopharmacology: modulators of behavior, mood and cognition. Current Neuropharmacology. 7: 195-206. PMID 20190961 DOI: 10.2174/157015909789152191  1
2009 Yu C, Gupta J, Chen JF, Yin HH. Genetic deletion of A2A adenosine receptors in the striatum selectively impairs habit formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 15100-3. PMID 19955361 DOI: 10.1523/JNEUROSCI.4215-09.2009  1
2009 Zhou SJ, Zhu ME, Shu D, Du XP, Song XH, Wang XT, Zheng RY, Cai XH, Chen JF, He JC. Preferential enhancement of working memory in mice lacking adenosine A(2A) receptors. Brain Research. 1303: 74-83. PMID 19785999 DOI: 10.1016/J.Brainres.2009.09.082  1
2009 Gui L, Duan W, Tian H, Li C, Zhu J, Chen JF, Zheng J. Adenosine A 2A receptor deficiency reduces striatal glutamate outflow and attenuates brain injury induced by transient focal cerebral ischemia in mice. Brain Research. 1297: 185-93. PMID 19703429 DOI: 10.1016/J.Brainres.2009.08.050  0.01
2009 Tebano MT, Martire A, Chiodi V, Pepponi R, Ferrante A, Domenici MR, Frank C, Chen JF, Ledent C, Popoli P. Adenosine A2A receptors enable the synaptic effects of cannabinoid CB1 receptors in the rodent striatum. Journal of Neurochemistry. 110: 1921-30. PMID 19627447 DOI: 10.1111/J.1471-4159.2009.06282.X  0.01
2009 Duan W, Gui L, Zhou Z, Liu Y, Tian H, Chen JF, Zheng J. Adenosine A2A receptor deficiency exacerbates white matter lesions and cognitive deficits induced by chronic cerebral hypoperfusion in mice. Journal of the Neurological Sciences. 285: 39-45. PMID 19524941 DOI: 10.1016/J.Jns.2009.05.010  0.01
2009 Kalda A, Herm L, Rinken A, Zharkovsky A, Chen JF. Co-administration of the partial dopamine D2 agonist terguride with L-dopa attenuates L-dopa-induced locomotor sensitization in hemiparkinsonian mice. Behavioural Brain Research. 202: 232-7. PMID 19463706 DOI: 10.1016/j.bbr.2009.03.037  0.01
2009 Wang H, Zhang W, Zhu C, Bucher C, Blazar BR, Zhang C, Chen JF, Linden J, Wu C, Huo Y. Inactivation of the adenosine A2A receptor protects apolipoprotein E-deficient mice from atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1046-52. PMID 19407243 DOI: 10.1161/Atvbaha.109.188839  1
2009 Yu L, Coelho JE, Zhang X, Fu Y, Tillman A, Karaoz U, Fredholm BB, Weng Z, Chen JF. Uncovering multiple molecular targets for caffeine using a drug target validation strategy combining A 2A receptor knockout mice with microarray profiling. Physiological Genomics. 37: 199-210. PMID 19258493 DOI: 10.1152/Physiolgenomics.90353.2008  1
2009 Yang JN, Chen JF, Fredholm BB. Physiological roles of A1 and A2A adenosine receptors in regulating heart rate, body temperature, and locomotion as revealed using knockout mice and caffeine. American Journal of Physiology. Heart and Circulatory Physiology. 296: H1141-9. PMID 19218506 DOI: 10.1152/Ajpheart.00754.2008  1
2009 Yang GK, Chen JF, Kieffer TJ, Kwok YN. Regulation of somatostatin release by adenosine in the mouse stomach. The Journal of Pharmacology and Experimental Therapeutics. 329: 729-37. PMID 19208896 DOI: 10.1124/Jpet.108.146050  0.01
2009 Miekisiak G, Yoo K, Sandler AL, Kulik TB, Chen JF, Winn HR. The role of adenosine in hypercarbic hyperemia: in vivo and in vitro studies in adenosine 2(A) receptor knockout and wild-type mice. Journal of Neurosurgery. 110: 981-8. PMID 19199466 DOI: 10.3171/2008.8.Jns08460  0.01
2009 Petzer JP, Castagnoli N, Schwarzschild MA, Chen JF, Van der Schyf CJ. Dual-target-directed drugs that block monoamine oxidase B and adenosine A(2A) receptors for Parkinson's disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 6: 141-51. PMID 19110205 DOI: 10.1016/J.Nurt.2008.10.035  0.01
2009 Wang XS, Chen YY, Shang XF, Zhu ZG, Chen GQ, Han Z, Shao B, Yang HM, Xu HQ, Chen JF, Zheng RY. Idazoxan attenuates spinal cord injury by enhanced astrocytic activation and reduced microglial activation in rat experimental autoimmune encephalomyelitis. Brain Research. 1253: 198-209. PMID 19083996 DOI: 10.1016/J.Brainres.2008.11.059  1
2009 Yang JN, Björklund O, Lindström-Törnqvist K, Lindgren E, Eriksson TM, Kahlström J, Chen JF, Schwarzschild MA, Tobler I, Fredholm BB. Mice heterozygous for both A1 and A(2A) adenosine receptor genes show similarities to mice given long-term caffeine. Journal of Applied Physiology (Bethesda, Md. : 1985). 106: 631-9. PMID 19036889 DOI: 10.1152/Japplphysiol.90971.2008  1
2009 Li W, Dai S, An J, Xiong R, Li P, Chen X, Zhao Y, Liu P, Wang H, Zhu P, Chen J, Zhou Y. Genetic inactivation of adenosine A2A receptors attenuates acute traumatic brain injury in the mouse cortical impact model. Experimental Neurology. 215: 69-76. PMID 18938161 DOI: 10.1016/J.Expneurol.2008.09.012  1
2008 Miekisiak G, Kulik T, Kusano Y, Kung D, Chen JF, Winn HR. Cerebral blood flow response in adenosine 2a receptor knockout mice during transient hypoxic hypoxia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 1656-64. PMID 18545261 DOI: 10.1038/Jcbfm.2008.57  0.01
2008 Cunha RA, Ferré S, Vaugeois JM, Chen JF. Potential therapeutic interest of adenosine A2A receptors in psychiatric disorders. Current Pharmaceutical Design. 14: 1512-24. PMID 18537674 DOI: 10.2174/138161208784480090  1
2008 Chen JF, Pedata F. Modulation of ischemic brain injury and neuroinflammation by adenosine A2A receptors. Current Pharmaceutical Design. 14: 1490-9. PMID 18537672 DOI: 10.2174/138161208784480126  1
2008 Shen HY, Coelho JE, Ohtsuka N, Canas PM, Day YJ, Huang QY, Rebola N, Yu L, Boison D, Cunha RA, Linden J, Tsien JZ, Chen JF. A critical role of the adenosine A2A receptor in extrastriatal neurons in modulating psychomotor activity as revealed by opposite phenotypes of striatum and forebrain A2A receptor knock-outs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 2970-5. PMID 18354001 DOI: 10.1523/Jneurosci.5255-07.2008  1
2008 Yu L, Shen HY, Coelho JE, Araújo IM, Huang QY, Day YJ, Rebola N, Canas PM, Rapp EK, Ferrara J, Taylor D, Müller CE, Linden J, Cunha RA, Chen JF. Adenosine A2A receptor antagonists exert motor and neuroprotective effects by distinct cellular mechanisms. Annals of Neurology. 63: 338-46. PMID 18300283 DOI: 10.1002/Ana.21313  1
2008 Tikh EI, Fenton RA, Chen JF, Schwarzschild MA, Dobson JG. Adenosine A1 and A2A receptor regulation of protein phosphatase 2A in the murine heart. Journal of Cellular Physiology. 216: 83-90. PMID 18181173 DOI: 10.1002/Jcp.21375  0.01
2008 Garcia GE, Truong LD, Li P, Zhang P, Du J, Chen JF, Feng L. Adenosine A2A receptor activation and macrophage-mediated experimental glomerulonephritis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 445-54. PMID 17898087 DOI: 10.1096/fj.07-8430com  1
2007 Dong F, An JH, Ren YP, Yan DS, Zhou XT, Lü F, Hu DN, Chen JF, Qu J. [Expression of dopamine receptor D2 and adenosine receptor A2A in human retinal pigment epithelium]. [Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology. 43: 1110-3. PMID 18331682 DOI: 10.3760/J.Issn:0412-4081.2007.12.013  1
2007 Chen JF, Sonsalla PK, Pedata F, Melani A, Domenici MR, Popoli P, Geiger J, Lopes LV, de Mendonça A. Adenosine A2A receptors and brain injury: broad spectrum of neuroprotection, multifaceted actions and "fine tuning" modulation. Progress in Neurobiology. 83: 310-31. PMID 18023959 DOI: 10.1016/J.Pneurobio.2007.09.002  1
2007 Yee BK, Singer P, Chen JF, Feldon J, Boison D. Transgenic overexpression of adenosine kinase in brain leads to multiple learning impairments and altered sensitivity to psychomimetic drugs. The European Journal of Neuroscience. 26: 3237-52. PMID 18005073 DOI: 10.1111/J.1460-9568.2007.05897.X  1
2007 Björklund O, Kahlström J, Salmi P, Ogren SO, Vahter M, Chen JF, Fredholm BB, Daré E. The effects of methylmercury on motor activity are sex- and age-dependent, and modulated by genetic deletion of adenosine receptors and caffeine administration. Toxicology. 241: 119-33. PMID 17920182 DOI: 10.1016/J.Tox.2007.08.092  1
2007 Mohsenin A, Mi T, Xia Y, Kellems RE, Chen JF, Blackburn MR. Genetic removal of the A2A adenosine receptor enhances pulmonary inflammation, mucin production, and angiogenesis in adenosine deaminase-deficient mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L753-61. PMID 17601796 DOI: 10.1152/Ajplung.00187.2007  1
2007 Deaglio S, Dwyer KM, Gao W, Friedman D, Usheva A, Erat A, Chen JF, Enjyoji K, Linden J, Oukka M, Kuchroo VK, Strom TB, Robson SC. Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. The Journal of Experimental Medicine. 204: 1257-65. PMID 17502665 DOI: 10.1084/Jem.20062512  1
2007 Kalda A, Heidmets LT, Shen HY, Zharkovsky A, Chen JF. Histone deacetylase inhibitors modulates the induction and expression of amphetamine-induced behavioral sensitization partially through an associated learning of the environment in mice. Behavioural Brain Research. 181: 76-84. PMID 17477979 DOI: 10.1016/J.Bbr.2007.03.027  1
2007 Haschemi A, Wagner O, Marculescu R, Wegiel B, Robson SC, Gagliani N, Gallo D, Chen JF, Bach FH, Otterbein LE. Cross-regulation of carbon monoxide and the adenosine A2a receptor in macrophages. Journal of Immunology (Baltimore, Md. : 1950). 178: 5921-9. PMID 17442976 DOI: 10.4049/Jimmunol.178.9.5921  0.01
2007 Huang QY, Yu L, Ferrante RJ, Chen JF. Mutant SOD1G93A in bone marrow-derived cells exacerbates 3-nitropropionic acid induced striatal damage in mice. Neuroscience Letters. 418: 175-80. PMID 17418947 DOI: 10.1016/J.Neulet.2007.03.038  1
2007 Coelho JE, Shen HY, Goldstein KR, Chen JF. What animal models have taught us about adenosine receptor function Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry. 7: 328-340. DOI: 10.2174/187152207781369869  1
2006 Xiao D, Bastia E, Xu YH, Benn CL, Cha JH, Peterson TS, Chen JF, Schwarzschild MA. Forebrain adenosine A2A receptors contribute to L-3,4-dihydroxyphenylalanine-induced dyskinesia in hemiparkinsonian mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 13548-55. PMID 17192438 DOI: 10.1523/Jneurosci.3554-06.2006  1
2006 Huang QY, Wei C, Yu L, Coelho JE, Shen HY, Kalda A, Linden J, Chen JF. Adenosine A2A receptors in bone marrow-derived cells but not in forebrain neurons are important contributors to 3-nitropropionic acid-induced striatal damage as revealed by cell-type-selective inactivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11371-8. PMID 17079665 DOI: 10.1523/Jneurosci.1907-06.2006  1
2006 Schwarzschild MA, Agnati L, Fuxe K, Chen JF, Morelli M. Targeting adenosine A2A receptors in Parkinson's disease. Trends in Neurosciences. 29: 647-54. PMID 17030429 DOI: 10.1016/J.Tins.2006.09.004  0.01
2006 Ohta A, Gorelik E, Prasad SJ, Ronchese F, Lukashev D, Wong MK, Huang X, Caldwell S, Liu K, Smith P, Chen JF, Jackson EK, Apasov S, Abrams S, Sitkovsky M. A2A adenosine receptor protects tumors from antitumor T cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 13132-7. PMID 16916931 DOI: 10.1073/Pnas.0605251103  1
2006 Kalda A, Yu L, Oztas E, Chen JF. Novel neuroprotection by caffeine and adenosine A(2A) receptor antagonists in animal models of Parkinson's disease. Journal of the Neurological Sciences. 248: 9-15. PMID 16806272 DOI: 10.1016/j.jns.2006.05.003  0.01
2006 Seeman P, Schwarz J, Chen JF, Szechtman H, Perreault M, McKnight GS, Roder JC, Quirion R, Boksa P, Srivastava LK, Yanai K, Weinshenker D, Sumiyoshi T. Psychosis pathways converge via D2high dopamine receptors. Synapse (New York, N.Y.). 60: 319-46. PMID 16786561 DOI: 10.1002/Syn.20303  1
2006 Lee HT, Kim M, Joo JD, Gallos G, Chen JF, Emala CW. A3 adenosine receptor activation decreases mortality and renal and hepatic injury in murine septic peritonitis. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 291: R959-69. PMID 16728466 DOI: 10.1152/ajpregu.00034.2006  0.01
2006 Bilbao A, Cippitelli A, Martín AB, Granado N, Ortiz O, Bezard E, Chen JF, Navarro M, Rodríguez de Fonseca F, Moratalla R. Absence of quasi-morphine withdrawal syndrome in adenosine A2A receptor knockout mice. Psychopharmacology. 185: 160-8. PMID 16470403 DOI: 10.1007/S00213-005-0284-0  1
2006 Xu K, Xu Y, Brown-Jermyn D, Chen JF, Ascherio A, Dluzen DE, Schwarzschild MA. Estrogen prevents neuroprotection by caffeine in the mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 535-41. PMID 16407551 DOI: 10.1523/Jneurosci.3008-05.2006  1
2006 Yu L, Schwarzschild MA, Chen JF. Cross-sensitization between caffeine- and L-dopa-induced behaviors in hemiparkinsonian mice. Neuroscience Letters. 393: 31-5. PMID 16236444 DOI: 10.1016/J.Neulet.2005.09.036  0.01
2005 Kachroo A, Orlando LR, Grandy DK, Chen JF, Young AB, Schwarzschild MA. Interactions between metabotropic glutamate 5 and adenosine A2A receptors in normal and parkinsonian mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10414-9. PMID 16280580 DOI: 10.1523/Jneurosci.3660-05.2005  1
2005 Shen HY, He JC, Wang Y, Huang QY, Chen JF. Geldanamycin induces heat shock protein 70 and protects against MPTP-induced dopaminergic neurotoxicity in mice. The Journal of Biological Chemistry. 280: 39962-9. PMID 16210323 DOI: 10.1074/jbc.M505524200  1
2005 Saura J, Angulo E, Ejarque A, Casadó V, Tusell JM, Moratalla R, Chen JF, Schwarzschild MA, Lluis C, Franco R, Serratosa J. Adenosine A2A receptor stimulation potentiates nitric oxide release by activated microglia. Journal of Neurochemistry. 95: 919-29. PMID 16092928 DOI: 10.1111/J.1471-4159.2005.03395.X  1
2005 Yu L, Haverty PM, Mariani J, Wang Y, Shen HY, Schwarzschild MA, Weng Z, Chen JF. Genetic and pharmacological inactivation of adenosine A2A receptor reveals an Egr-2-mediated transcriptional regulatory network in the mouse striatum. Physiological Genomics. 23: 89-102. PMID 16046619 DOI: 10.1152/Physiolgenomics.00068.2005  1
2005 Huang ZL, Qu WM, Eguchi N, Chen JF, Schwarzschild MA, Fredholm BB, Urade Y, Hayaishi O. Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine. Nature Neuroscience. 8: 858-9. PMID 15965471 DOI: 10.1038/Nn1491  1
2005 Fredholm BB, Chen JF, Masino SA, Vaugeois JM. Actions of adenosine at its receptors in the CNS: insights from knockouts and drugs. Annual Review of Pharmacology and Toxicology. 45: 385-412. PMID 15822182 DOI: 10.1146/Annurev.Pharmtox.45.120403.095731  1
2005 Fredholm BB, Chen JF, Cunha RA, Svenningsson P, Vaugeois JM. Adenosine and brain function. International Review of Neurobiology. 63: 191-270. PMID 15797469 DOI: 10.1016/S0074-7742(05)63007-3  1
2005 Bastia E, Xu YH, Scibelli AC, Day YJ, Linden J, Chen JF, Schwarzschild MA. A crucial role for forebrain adenosine A(2A) receptors in amphetamine sensitization. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 891-900. PMID 15602504 DOI: 10.1038/Sj.Npp.1300630  1
2004 Stevens B, Ishibashi T, Chen JF, Fields RD. Adenosine: an activity-dependent axonal signal regulating MAP kinase and proliferation in developing Schwann cells. Neuron Glia Biology. 1: 23-34. PMID 16429616 DOI: 10.1017/s1740925x04000055  0.01
2004 Frith MC, Fu Y, Yu L, Chen JF, Hansen U, Weng Z. Detection of functional DNA motifs via statistical over-representation. Nucleic Acids Research. 32: 1372-81. PMID 14988425 DOI: 10.1093/Nar/Gkh299  1
2004 Fink JS, Kalda A, Ryu H, Stack EC, Schwarzschild MA, Chen JF, Ferrante RJ. Genetic and pharmacological inactivation of the adenosine A2A receptor attenuates 3-nitropropionic acid-induced striatal damage. Journal of Neurochemistry. 88: 538-44. PMID 14720203 DOI: 10.1046/J.1471-4159.2003.02145.X  1
2004 Sakata M, Eguchi N, Qu WM, Huang ZL, Chen JF, Schwarzschild MA, Urade Y, Hayaishi O. Lack of rebound of non-rapid eye movement sleep after sleep deprivation in adenosine A2A receptor knockout mice Sleep and Biological Rhythms. 2: S56. DOI: 10.1111/J.1479-8425.2004.00115.X  1
2004 Qu WM, Huang ZL, Mochizuki T, Eguchi N, Chen JF, Schwarzschild MA, Fink SJ, Urade Y, Hayaishi O. Adenosine A2A receptor deficiency attenuates the somnogenic effect of prostaglandin D2 Sleep and Biological Rhythms. 2: S55. DOI: 10.1111/J.1479-8425.2004.00114.X  1
2004 Chen J, Schwarzschild MA. Adenosine A2A receptors and neuroadaptation: Possible implications in sleep-wake physiology Sleep and Biological Rhythms. 2. DOI: 10.1111/J.1479-8425.2004.00093.X  0.01
2003 Urade Y, Eguchi N, Qu WM, Sakata M, Huang ZL, Chen JF, Schwarzschild MA, Fink JS, Hayaishi O. Sleep regulation in adenosine A2A receptor-deficient mice. Neurology. 61: S94-6. PMID 14663019 DOI: 10.1212/01.Wnl.0000095222.41066.5E  1
2003 Castagnoli N, Petzer JP, Steyn S, Castagnoli K, Chen JF, Schwarzschild MA, Van der Schyf CJ. Monoamine oxidase B inhibition and neuroprotection: studies on selective adenosine A2A receptor antagonists. Neurology. 61: S62-8. PMID 14663013 DOI: 10.1212/01.Wnl.0000095215.97585.59  0.01
2003 Schwarzschild MA, Xu K, Oztas E, Petzer JP, Castagnoli K, Castagnoli N, Chen JF. Neuroprotection by caffeine and more specific A2A receptor antagonists in animal models of Parkinson's disease. Neurology. 61: S55-61. PMID 14663012 DOI: 10.1212/01.Wnl.0000095214.53646.72  0.01
2003 Chen J, Chase T, Schwarzschild M. J. Stephen Fink, MD, PhD (1950–2002) Neurology. 61. PMID 14663000 DOI: 10.1212/01.Wnl.0000095201.55121.8A  0.01
2003 Day YJ, Huang L, McDuffie MJ, Rosin DL, Ye H, Chen JF, Schwarzschild MA, Fink JS, Linden J, Okusa MD. Renal protection from ischemia mediated by A2A adenosine receptors on bone marrow-derived cells. The Journal of Clinical Investigation. 112: 883-91. PMID 12975473 DOI: 10.1172/Jci15483  1
2003 Schwarzschild MA, Chen JF, Chase TN. A2A antagonists for PD: A prime example of translational neuroscience Neurology. 61: S3-S4. DOI: 10.1212/01.Wnl.0000095202.94814.0F  1
2002 Schwarzschild MA, Chen J, Ascherio A. Caffeinated clues and the promise of adenosine A2A antagonists in PD Neurology. 58: 1154-1160. PMID 11971080 DOI: 10.1212/Wnl.58.8.1154  0.01
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