Samuel M. Poloyac - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Pharmacy, Neuroscience Biology, General

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Osier ND, Ziari M, Puccio AM, Poloyac S, Okonkwo DO, Minnigh MB, Beers SR, Conley YP. Elevated cerebrospinal fluid concentrations of N-acetylaspartate correlate with poor outcome in a pilot study of severe brain trauma. Brain Injury. 1-8. PMID 31305157 DOI: 10.1080/02699052.2019.1641743  0.33
2019 Abrahamson EE, Poloyac SM, Dixon CE, Dekosky ST, Ikonomovic MD. Acute and chronic effects of single dose memantine after controlled cortical impact injury in adult rats. Restorative Neurology and Neuroscience. PMID 31177251 DOI: 10.3233/Rnn-190909  0.33
2019 Poloyac SM, Bertz RJ, McDermott L, Marathe P. Pharmacological Optimization for Successful Traumatic Brain Injury Drug Development. Journal of Neurotrauma. PMID 30816062 DOI: 10.1089/Neu.2018.6295  0.326
2019 Hagos FT, Adams SM, Poloyac SM, Kochanek PM, Horvat CM, Clark RSB, Empey PE. Membrane transporters in traumatic brain injury: Pathological, pharmacotherapeutic, and developmental implications. Experimental Neurology. PMID 30797827 DOI: 10.1016/J.Expneurol.2019.02.011  0.331
2018 Kochanek PM, Jackson TC, Jha R, Clark RSB, Okonkwo DO, Bayir H, Poloyac SM, Wagner AK, Empey PE, Conley YP, Bell MJ, Kline AE, Bondi CO, Simon DW, Carlson SW, et al. Paths to successful translation of new therapies for severe TBI in the golden age of traumatic brain injury research: A Pittsburgh vision. Journal of Neurotrauma. PMID 30520681 DOI: 10.1089/Neu.2018.6203  0.327
2018 Kochanek PM, Dixon CE, Mondello S, Wang KKK, Lafrenaye A, Bramlett HM, Dietrich WD, Hayes RL, Shear DA, Gilsdorf JS, Catania M, Poloyac SM, Empey PE, Jackson TC, Povlishock JT. Multi-Center Pre-clinical Consortia to Enhance Translation of Therapies and Biomarkers for Traumatic Brain Injury: Operation Brain Trauma Therapy and Beyond. Frontiers in Neurology. 9: 640. PMID 30131759 DOI: 10.3389/Fneur.2018.00640  0.327
2018 DeWitt D, Hawkins BE, Dixon CE, Kochanek PM, Armstead WM, Bass C', Bramlett HM, Büki A, Dietrich WD, Ferguson AR, Hall ED, Hayes RL, Hinds Ii CSR, LaPlaca M, Long J, ... ... Poloyac SM, et al. Preclinical Testing of Therapies for Traumatic Brain Injury. Journal of Neurotrauma. PMID 29756522 DOI: 10.1089/Neu.2018.5778  0.34
2018 Hagos FT, Empey PE, Wang P, Ma X, Poloyac SM, Bayır H, Kochanek PM, Bell MJ, Clark RSB. Exploratory Application of Neuropharmacometabolomics in Severe Childhood Traumatic Brain Injury. Critical Care Medicine. PMID 29742587 DOI: 10.1097/Ccm.0000000000003203  0.323
2018 Jha R, Molyneaux BJ, Jackson TC, Wallisch J, Park SY, Poloyac SM, Vagni VA, Janesko-Feldman KL, Hoshitsuki K, Minnigh MB, Kochanek PM. Glibenclamide produces region-dependent effects on cerebral edema in a combined injury model of traumatic brain injury and hemorrhagic shock in mice. Journal of Neurotrauma. PMID 29648981 DOI: 10.1089/Neu.2016.4696  0.351
2018 Kochanek PM, Bramlett HM, Dixon CE, Dietrich WD, Mondello S, Wang KKW, Hayes RL, Lafrenaye A, Povlishock JT, Tortella FC, Poloyac SM, Empey P, Shear DA. Operation Brain Trauma Therapy: 2016 Update. Military Medicine. 183: 303-312. PMID 29635589 DOI: 10.1093/Milmed/Usx184  0.333
2017 Adams SM, Conley YP, Wagner AK, Jha RM, Clark RS, Poloyac SM, Kochanek PM, Empey PE. The pharmacogenomics of severe traumatic brain injury. Pharmacogenomics. PMID 28975867 DOI: 10.2217/Pgs-2017-0073  0.34
2017 Stanfill A, Simpson C, Sherwood P, Poloyac S, Crago E, Kim H, Conley Y. A pilot study on the impact of dopamine, serotonin, and brain-derived neurotrophic factor genotype on long-term functional outcomes after subarachnoid hemorrhage. Sage Open Medicine. 5: 2050312117726725. PMID 28894586 DOI: 10.1177/2050312117726725  0.307
2017 Clark RSB, Empey PE, Bayır H, Rosario BL, Poloyac SM, Kochanek PM, Nolin TD, Au AK, Horvat CM, Wisniewski SR, Bell MJ. Phase I randomized clinical trial of N-acetylcysteine in combination with an adjuvant probenecid for treatment of severe traumatic brain injury in children. Plos One. 12: e0180280. PMID 28686657 DOI: 10.1371/Journal.Pone.0180280  0.344
2016 Jha RM, Puccio AM, Chou SH, Chang CH, Wallisch JS, Molyneaux BJ, Zusman BE, Shutter LA, Poloyac SM, Janesko-Feldman KL, Okonkwo DO, Kochanek PM. Sulfonylurea Receptor-1: A Novel Biomarker for Cerebral Edema in Severe Traumatic Brain Injury. Critical Care Medicine. PMID 27845954 DOI: 10.1097/Ccm.0000000000002079  0.345
2016 Hagos FT, Daood MJ, Ocque JA, Nolin TD, Bayir H, Poloyac SM, Kochanek PM, Clark RS, Empey PE. Probenecid, an organic anion transporter 1 and 3 inhibitor, increases plasma and brain exposure of N-acetylcysteine. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-8. PMID 27278858 DOI: 10.1080/00498254.2016.1187777  0.306
2016 Li J, Oberly PJ, Poloyac SM, Gibbs RB. A microsomal based method to detect aromatase activity in different brain regions of the rat using ultra performance liquid chromatography-mass spectrometry. The Journal of Steroid Biochemistry and Molecular Biology. PMID 27113434 DOI: 10.1016/J.Jsbmb.2016.04.013  0.3
2015 Browning M, Shear DA, Bramlett HM, Dixon CE, Mondello S, Schmid Maj KE, Poloyac SM, Dietrich WD, Hayes RL, Wang KK, Povlishock J, Tortella FC, Kochanek PM. Levetiracetam Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671550 DOI: 10.1089/Neu.2015.4131  0.335
2015 Kochanek PM, Bramlett HM, Shear DA, Dixon CE, Mondello S, Dietrich WD, Hayes RL, Wang KK, Poloyac SM, Empey P, Povlishock J, Mountney A, Browning M, Deng-Bryant Y, Yan HQ, et al. Synthesis of Findings, Current Investigations, and Future Directions: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671284 DOI: 10.1089/Neu.2015.4133  0.334
2015 Jha R, Molyneaux B, Jackson T, Wallisch J, Vagni V, Poloyac S, Dixon C, Kochanek P. 491: GLIBENCLAMIDE REDUCES DIFFUSE CEREBRAL EDEMA IN A COMBINED MODEL OF TRAUMATIC BRAIN INJURY AND SHOCK. Critical Care Medicine. 43: 124. PMID 26570152 DOI: 10.1097/01.Ccm.0000474319.38132.1B  0.318
2015 Mountney A, Bramlett HM, Dixon CE, Mondello S, Dietrich WD, Wang KK, Caudle KL, Empey P, Poloyac SM, Hayes RL, Povlishock J, Tortella FC, Kochanek PM, Shear DA. Simvastatin Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26541177 DOI: 10.1089/Neu.2015.4130  0.369
2015 Donnelly MK, Crago EA, Conley YP, Balzer JR, Ren D, Ducruet AF, Kochanek PM, Sherwood PR, Poloyac SM. 20-HETE is associated with unfavorable outcomes in subarachnoid hemorrhage patients. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 1515-22. PMID 25920956 DOI: 10.1038/Jcbfm.2015.75  0.312
2015 Kochanek PM, Jackson TC, Ferguson NM, Carlson SW, Simon DW, Brockman EC, Ji J, Bay?r H, Poloyac SM, Wagner AK, Kline AE, Empey PE, Clark RS, Jackson EK, Dixon CE. Emerging therapies in traumatic brain injury. Seminars in Neurology. 35: 83-100. PMID 25714870 DOI: 10.1055/S-0035-1544237  0.336
2015 Donnelly MK, Conley YP, Crago EA, Ren D, Sherwood PR, Balzer JR, Poloyac SM. Genetic markers in the EET metabolic pathway are associated with outcomes in patients with aneurysmal subarachnoid hemorrhage. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 267-76. PMID 25388680 DOI: 10.1038/Jcbfm.2014.195  0.32
2014 Crago EA, Sherwood PR, Bender C, Balzer J, Ren D, Poloyac SM. Plasma Estrogen Levels Are Associated With Severity of Injury and Outcomes After Aneurysmal Subarachnoid Hemorrhage. Biological Research For Nursing. PMID 25548393 DOI: 10.1177/1099800414561632  0.312
2013 Shaik JS, Ahmad M, Li W, Rose ME, Foley LM, Hitchens TK, Graham SH, Hwang SH, Hammock BD, Poloyac SM. Soluble epoxide hydrolase inhibitor trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is neuroprotective in rat model of ischemic stroke. American Journal of Physiology. Heart and Circulatory Physiology. 305: H1605-13. PMID 24043255 DOI: 10.1152/Ajpheart.00471.2013  0.316
2013 Empey PE, de Mendizabal NV, Bell MJ, Bies RR, Anderson KB, Kochanek PM, Adelson PD, Poloyac SM. Therapeutic hypothermia decreases phenytoin elimination in children with traumatic brain injury. Critical Care Medicine. 41: 2379-87. PMID 23896831 DOI: 10.1097/Ccm.0B013E318292316C  0.366
2013 Liu H, Rose ME, Miller TM, Li W, Shinde SN, Pickrell AM, Poloyac SM, Graham SH, Hickey RW. COX2-derived primary and cyclopentenone prostaglandins are increased after asphyxial cardiac arrest. Brain Research. 1519: 71-7. PMID 23624225 DOI: 10.1016/J.Brainres.2013.04.029  0.342
2013 Thampatty BP, Klamerus MM, Oberly PJ, Feldman KL, Bell MJ, Tyler-Kabara EC, Adelson PD, Clark RS, Kochanek PM, Poloyac SM. Hypothermia decreases cerebrospinal fluid asymmetric dimethylarginine levels in children with traumatic brain injury. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 14: 403-12. PMID 23439461 DOI: 10.1097/Pcc.0B013E31827212C0  0.331
2011 Zhou J, Empey PE, Bies RR, Kochanek PM, Poloyac SM. Cardiac arrest and therapeutic hypothermia decrease isoform-specific cytochrome P450 drug metabolism. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 2209-18. PMID 21868471 DOI: 10.1124/Dmd.111.040642  0.305
2011 Crago EA, Thampatty BP, Sherwood PR, Kuo CW, Bender C, Balzer J, Horowitz M, Poloyac SM. Cerebrospinal fluid 20-HETE is associated with delayed cerebral ischemia and poor outcomes after aneurysmal subarachnoid hemorrhage. Stroke; a Journal of Cerebral Circulation. 42: 1872-7. PMID 21617146 DOI: 10.1161/Strokeaha.110.605816  0.325
2010 Salonia R, Empey PE, Poloyac SM, Wisniewski SR, Klamerus M, Ozawa H, Wagner AK, Ruppel R, Bell MJ, Feldman K, Adelson PD, Clark RS, Kochanek PM. Endothelin-1 is increased in cerebrospinal fluid and associated with unfavorable outcomes in children after severe traumatic brain injury. Journal of Neurotrauma. 27: 1819-25. PMID 20684675 DOI: 10.1089/Neu.2010.1402  0.336
2009 Miller TM, Donnelly MK, Crago EA, Roman DM, Sherwood PR, Horowitz MB, Poloyac SM. Rapid, simultaneous quantitation of mono and dioxygenated metabolites of arachidonic acid in human CSF and rat brain. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 877: 3991-4000. PMID 19892608 DOI: 10.1016/J.Jchromb.2009.10.012  0.326
2008 Mu Y, Klamerus MM, Miller TM, Rohan LC, Graham SH, Poloyac SM. Intravenous formulation of N-hydroxy-N'-(4-n-butyl-2-methylphenyl)formamidine (HET0016) for inhibition of rat brain 20-hydroxyeicosatetraenoic acid formation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 2324-30. PMID 18725506 DOI: 10.1124/Dmd.108.023150  0.326
2007 Tortorici MA, Kochanek PM, Poloyac SM. Effects of hypothermia on drug disposition, metabolism, and response: A focus of hypothermia-mediated alterations on the cytochrome P450 enzyme system. Critical Care Medicine. 35: 2196-204. PMID 17855837 DOI: 10.1097/01.Ccm.0000281517.97507.6E  0.308
2006 Poloyac SM, Zhang Y, Bies RR, Kochanek PM, Graham SH. Protective effect of the 20-HETE inhibitor HET0016 on brain damage after temporary focal ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 26: 1551-61. PMID 16570075 DOI: 10.1038/Sj.Jcbfm.9600309  0.332
2006 Tortorici MA, Kochanek PM, Bies RR, Poloyac SM. Therapeutic hypothermia-induced pharmacokinetic alterations on CYP2E1 chlorzoxazone-mediated metabolism in a cardiac arrest rat model. Critical Care Medicine. 34: 785-91. PMID 16521272 DOI: 10.1097/01.Ccm.0000201899.52739.4F  0.304
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