Hulya Bayir - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Public Health, Neuroscience Biology, Cell Biology

145 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Bao Z, Liu Y, Chen B, Miao Z, Tu Y, Li C, Chao H, Ye Y, Xu X, Sun G, Zhao P, Liu N, Liu Y, Wang X, Lam SM, et al. Prokineticin-2 prevents neuronal cell deaths in a model of traumatic brain injury. Nature Communications. 12: 4220. PMID 34244497 DOI: 10.1038/s41467-021-24469-y  0.523
2020 Zhao J, Dar HH, Deng Y, St Croix CM, Li Z, Minami Y, Shrivastava IH, Tyurina YY, Etling E, Rosenbaum JC, Nagasaki T, Trudeau JB, Watkins SC, Bahar I, Bayır H, et al. PEBP1 acts as a rheostat between prosurvival autophagy and ferroptotic death in asthmatic epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 32513718 DOI: 10.1073/Pnas.1921618117  0.342
2020 Lamade AM, Anthonymuthu TS, Hier ZE, Gao Y, Kagan VE, Bayır H. Mitochondrial damage & lipid signaling in traumatic brain injury. Experimental Neurology. 113307. PMID 32289317 DOI: 10.1016/J.Expneurol.2020.113307  0.459
2020 Bayır H, Anthonymuthu TS, Tyurina YY, Patel SJ, Amoscato AA, Lamade AM, Yang Q, Vladimirov GK, Philpott CC, Kagan VE. Achieving Life through Death: Redox Biology of Lipid Peroxidation in Ferroptosis. Cell Chemical Biology. PMID 32275865 DOI: 10.1016/J.Chembiol.2020.03.014  0.388
2020 Kapralov AA, Yang Q, Dar HH, Tyurina YY, Anthonymuthu TS, Kim R, St Croix CM, Mikulska-Ruminska K, Liu B, Shrivastava IH, Tyurin VA, Ting HC, Wu YL, Gao Y, Shurin GV, et al. Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death. Nature Chemical Biology. 16: 278-290. PMID 32080625 DOI: 10.1038/S41589-019-0462-8  0.321
2019 Kagan VE, Tyurina YY, Sun WY, Vlasova LL, Dar H, Tyurin VA, Amoscato AA, Mallampalli R, van der Wel PCA, He RR, Shvedova AA, Gabrilovich D, Bayir H. Redox phospholipidomics of enzymatically generated oxygenated phospholipids as specific signals of programmed cell death. Free Radical Biology & Medicine. PMID 31883467 DOI: 10.1016/J.Freeradbiomed.2019.12.028  0.36
2019 Artyukhova MA, Tyurina YY, Chu CT, Zharikova TM, Bayir H, Kagan VE, Timashev PS. Interrogating Parkinson's disease associated redox targets: Potential application of CRISPR editing. Free Radical Biology & Medicine. PMID 31201850 DOI: 10.1016/J.Freeradbiomed.2019.06.007  0.31
2019 Tyurina YY, St Croix CM, Watkins SC, Watson AM, Epperly MW, Anthonymuthu TS, Kisin ER, Vlasova II, Krysko O, Krysko DV, Kapralov AA, Dar HH, Tyurin VA, Amoscato AA, Popova EN, ... ... Bayir H, et al. Redox (phospho)lipidomics of signaling in inflammation and programmed cell death. Journal of Leukocyte Biology. PMID 31071242 DOI: 10.1002/Jlb.3Mir0119-004Rr  0.341
2019 Anthonymuthu TS, Kenny EM, Hier ZE, Clark RSB, Kochanek PM, Kagan VE, Bayır H. Detection of brain specific cardiolipins in plasma after experimental pediatric head injury. Experimental Neurology. PMID 30981805 DOI: 10.1016/J.Expneurol.2019.04.007  0.441
2019 Y Tyurina Y, Tyurin VA, Anthonymuthu T, Amoscato AA, Sparvero LJ, Nesterova AM, Baynard ML, Sun W, He R, Khaitovich P, Vladimirov YA, Gabrilovich DI, Bayir H, Kagan VE. "Redox lipidomics technology: Looking for a needle in a haystack". Chemistry and Physics of Lipids. PMID 30928338 DOI: 10.1016/J.Chemphyslip.2019.03.012  0.333
2019 Anthonymuthu TS, Kenny EM, Lamade AM, Gidwani H, Krehel NM, Misse A, Gao X, Amoscato AA, Straub AC, Kagan VE, Dezfulian C, Bayır H. Lipidomics Detection of Brain Cardiolipins in Plasma Is Associated With Outcome After Cardiac Arrest. Critical Care Medicine. 47: e292-e300. PMID 30855329 DOI: 10.1097/Ccm.0000000000003636  0.387
2019 Chao H, Lin C, Zuo Q, Liu Y, Xiao M, Xu X, Li Z, Bao Z, Chen H, You Y, Kochanek PM, Yin H, Liu N, Kagan VE, Bayır H, et al. Cardiolipin-dependent mitophagy guides outcome after traumatic brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30626699 DOI: 10.1523/Jneurosci.3415-17.2018  0.597
2019 Soysal E, Horvat C, Simon D, Kochanek P, Clark R, Bayir H. 1811: Predictors Of Deterioration And Neurocritical Care Use In Pediatric Moderate Traumatic Brain Injury Critical Care Medicine. 47: 879. DOI: 10.1097/01.Ccm.0000552549.96071.1C  0.383
2018 Kenny EM, Fidan E, Yang Q, Anthonymuthu TS, New LA, Meyer EA, Wang H, Kochanek PM, Dixon CE, Kagan VE, Bayır H. Ferroptosis Contributes to Neuronal Death and Functional Outcome After Traumatic Brain Injury. Critical Care Medicine. PMID 30531185 DOI: 10.1097/Ccm.0000000000003555  0.475
2018 Kochanek PM, Jackson TC, Jha R, Clark RSB, Okonkwo DO, Bayir H, Poloyac SM, Wagner AK, Empey PE, Conley YP, Bell MJ, Kline AE, Bondi CO, Simon DW, Carlson SW, et al. Paths to successful translation of new therapies for severe TBI in the golden age of traumatic brain injury research: A Pittsburgh vision. Journal of Neurotrauma. PMID 30520681 DOI: 10.1089/Neu.2018.6203  0.338
2018 Chao H, Anthonymuthu TS, Kenny EM, Amoscato AA, Cole LK, Hatch GM, Ji J, Kagan VE, Bayır H. Disentangling oxidation/hydrolysis reactions of brain mitochondrial cardiolipins in pathogenesis of traumatic injury. Jci Insight. 3. PMID 30385716 DOI: 10.1172/Jci.Insight.97677  0.609
2018 Dar HH, Tyurina YY, Mikulska-Ruminska K, Shrivastava I, Ting HC, Tyurin VA, Krieger J, St Croix CM, Watkins S, Bayir E, Mao G, Ambruster C, Kapralov A, Wang H, Parsek MH, et al. Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium. The Journal of Clinical Investigation. PMID 30198910 DOI: 10.1172/Jci99490  0.337
2018 Krainz T, Lamade A, Du L, Maskrey T, Calderon M, Watkins S, Epperly M, Greenberger JS, Bayir H, Wipf P, Clark R. Synthesis and Evaluation of a Mitochondria-Targeting Poly(ADP-ribose) Polymerase-1 Inhibitor. Acs Chemical Biology. PMID 30184433 DOI: 10.1021/Acschembio.8B00423  0.317
2018 Cole LK, Kim JH, Amoscato AA, Tyurina YY, Bayır H, Karimi B, Siddiqui TJ, Kagan VE, Hatch GM, Kauppinen TM. Aberrant cardiolipin metabolism is associated with cognitive deficiency and hippocampal alteration in tafazzin knockdown mice. Biochimica Et Biophysica Acta. PMID 30055293 DOI: 10.1016/J.Bbadis.2018.07.022  0.368
2018 Lamade AM, Kenny EM, Anthonymuthu TS, Soysal E, Clark R, Kagan VE, Bayır H. Aiming for the Target: Mitochondrial Drug Delivery in Traumatic Brain Injury. Neuropharmacology. PMID 30009835 DOI: 10.1016/J.Neuropharm.2018.07.014  0.424
2018 Anthonymuthu TS, Kenny EM, Lamade AM, Kagan VE, Bayır H. OXIDIZED PHOSPHOLIPID SIGNALING IN TRAUMATIC BRAIN INJURY. Free Radical Biology & Medicine. PMID 29964171 DOI: 10.1016/J.Freeradbiomed.2018.06.031  0.456
2018 Lou W, Ting HC, Reynolds CJ, Tyurina YY, Tyurin VA, Li Y, Ji J, Yu W, Liang Z, Stoyanovsky DA, Anthonymuthu TS, Frasso MA, Wipf P, Greenberger JS, Bayir H, et al. Genetic re-engineering of polyunsaturated phospholipid profile of Saccharomyces cerevisiae identifies a novel role for Cld1 in mitigating the effects of cardiolipin peroxidation. Biochimica Et Biophysica Acta. PMID 29935382 DOI: 10.1016/J.Bbalip.2018.06.016  0.338
2018 Conrad M, Kagan VE, Bayir H, Pagnussat GC, Head B, Traber MG, Stockwell BR. Regulation of lipid peroxidation and ferroptosis in diverse species. Genes & Development. 32: 602-619. PMID 29802123 DOI: 10.1101/Gad.314674.118  0.3
2018 Hagos FT, Empey PE, Wang P, Ma X, Poloyac SM, Bayır H, Kochanek PM, Bell MJ, Clark RSB. Exploratory Application of Neuropharmacometabolomics in Severe Childhood Traumatic Brain Injury. Critical Care Medicine. PMID 29742587 DOI: 10.1097/Ccm.0000000000003203  0.391
2018 Fidan E, Foley LM, New LA, Alexander H, Kochanek PM, Hitchens TK, Bayır H. Metabolic and Structural Imaging at 7 Tesla After Repetitive Mild Traumatic Brain Injury in Immature Rats. Asn Neuro. 10: 1759091418770543. PMID 29741097 DOI: 10.1177/1759091418770543  0.377
2018 Wolf MS, Bayır H, Kochanek PM, Clark RSB. The role of autophagy in acute brain injury: A state of flux? Neurobiology of Disease. PMID 29704549 DOI: 10.1016/J.Nbd.2018.04.018  0.398
2018 Simon D, McGeachy M, Raphael I, Vagni V, Kochanek P, Bayir H, Clark R. 1571: Role Of Il-17 After Traumatic Brain Injury In Adult Mice Critical Care Medicine. 46: 770. DOI: 10.1097/01.Ccm.0000529572.79638.24  0.351
2018 Bayır H, Anthonymuthu TS, Kenny EM, Lamade AM, Gidwani H, Krehel NM, Misse A, Amoscato AA, Straub AC, Dezfulian C, Kagan VE. Detection of brain cardiolipins in plasma after cardiac arrest Free Radical Biology and Medicine. 120. DOI: 10.1016/J.Freeradbiomed.2018.04.441  0.414
2017 Kochanek PM, Wallisch JS, Bayır H, Clark RSB. Pre-clinical models in pediatric traumatic brain injury-challenges and lessons learned. Child's Nervous System : Chns : Official Journal of the International Society For Pediatric Neurosurgery. 33: 1693-1701. PMID 29149385 DOI: 10.1007/S00381-017-3474-2  0.387
2017 Wenzel SE, Tyurina YY, Zhao J, St Croix CM, Dar HH, Mao G, Tyurin VA, Anthonymuthu TS, Kapralov AA, Amoscato AA, Mikulska-Ruminska K, Shrivastava IH, Kenny EM, Yang Q, Rosenbaum JC, et al. PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals. Cell. 171: 628-641.e26. PMID 29053969 DOI: 10.1016/J.Cell.2017.09.044  0.344
2017 Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, et al. Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease. Cell. 171: 273-285. PMID 28985560 DOI: 10.1016/J.Cell.2017.09.021  0.37
2017 Kim-Campbell N, Gretchen C, Callaway C, Felmet K, Kochanek PM, Maul T, Wearden P, Sharma M, Viegas M, Munoz R, Gladwin MT, Bayir H. Cell-Free Plasma Hemoglobin and Male Gender Are Risk Factors for Acute Kidney Injury in Low Risk Children Undergoing Cardiopulmonary Bypass. Critical Care Medicine. PMID 28863013 DOI: 10.1097/Ccm.0000000000002703  0.305
2017 Simon DW, McGeachy MJ, Bayır H, Clark RSB, Loane DJ, Kochanek PM. The far-reaching scope of neuroinflammation after traumatic brain injury. Nature Reviews. Neurology. PMID 28776601 DOI: 10.1038/nrneurol.2017.116  0.303
2017 Clark RSB, Empey PE, Bayır H, Rosario BL, Poloyac SM, Kochanek PM, Nolin TD, Au AK, Horvat CM, Wisniewski SR, Bell MJ. Phase I randomized clinical trial of N-acetylcysteine in combination with an adjuvant probenecid for treatment of severe traumatic brain injury in children. Plos One. 12: e0180280. PMID 28686657 DOI: 10.1371/Journal.Pone.0180280  0.395
2017 Anthonymuthu TS, Kim-Campbell N, Bayır H. Oxidative lipidomics: applications in critical care. Current Opinion in Critical Care. 23: 251-256. PMID 28661413 DOI: 10.1097/Mcc.0000000000000419  0.307
2017 Kochanek PM, Bayir H. Titrating the dose of oxygen after severe traumatic brain injury in the era of precision medicine. Journal of Neurotrauma. PMID 28537530 DOI: 10.1089/Neu.2017.5159  0.386
2017 Anthonymuthu TS, Kenny EM, Amoscato AA, Lewis J, Kochanek PM, Kagan VE, Bayır H. Global assessment of oxidized free fatty acids in brain reveals an enzymatic predominance to oxidative signaling after trauma. Biochimica Et Biophysica Acta. PMID 28347845 DOI: 10.1016/J.Bbadis.2017.03.015  0.391
2017 Tian H, Sparvero LJ, Amoscato AA, Bloom A, Bayır H, Kagan VE, Winograd N. Gas Cluster Ion Beam Time-of-Flight Secondary Ion Mass Spectrometry High-Resolution Imaging of Cardiolipin Speciation in the Brain: Identification of Molecular Losses after Traumatic Injury. Analytical Chemistry. 89: 4611-4619. PMID 28306235 DOI: 10.1021/Acs.Analchem.7B00164  0.351
2017 Kagan VE, Bayır H, Tyurina YY, Bolevich SB, Maguire JJ, Fadeel B, Balasubramanian K. Elimination of the unnecessary: Intra- and extracellular signaling by anionic phospholipids. Biochemical and Biophysical Research Communications. 482: 482-490. PMID 28212735 DOI: 10.1016/J.Bbrc.2016.11.005  0.34
2017 Simon DW, McGeachy MJ, Bayır H, Clark RS, Loane DJ, Kochanek PM. The far-reaching scope of neuroinflammation after traumatic brain injury. Nature Reviews. Neurology. PMID 28186177 DOI: 10.1038/Nrneurol.2017.13  0.411
2017 Wallisch JS, Simon DW, Bayır H, Bell MJ, Kochanek PM, Clark RS. Cerebrospinal Fluid NLRP3 is Increased After Severe Traumatic Brain Injury in Infants and Children. Neurocritical Care. PMID 28181102 DOI: 10.1007/S12028-017-0378-7  0.398
2017 Otulakowski G, Engelberts D, Arima H, Hirate H, Bayir H, Post M, Kavanagh BP. α-Tocopherol transfer protein mediates protective hypercapnia in murine ventilator-induced lung injury. Thorax. PMID 28159772 DOI: 10.1136/Thoraxjnl-2016-209501  0.343
2017 Bayır H. Signaling by Oxidized Lipids in Acute Brain Injury Free Radical Biology and Medicine. 108. DOI: 10.1016/J.Freeradbiomed.2017.04.361  0.473
2016 Au AK, Aneja RK, Bayır H, Bell MJ, Janesko-Feldman K, Kochanek PM, Clark RS. Autophagy Biomarkers Beclin 1 and p62 are Increased in Cerebrospinal Fluid after Traumatic Brain Injury. Neurocritical Care. PMID 28000126 DOI: 10.1007/S12028-016-0351-X  0.396
2016 Tyurina YY, Lou W, Qu F, Tyurin VA, Mohammadyani D, Liu J, Hüttemann M, Frasso MA, Wipf P, Bayir H, Greenberg ML, Kagan VE. Lipidomics Characterization of Biosynthetic and Remodeling Pathways of Cardiolipins in Genetically and Nutritionally Manipulated Yeast Cells. Acs Chemical Biology. PMID 27982579 DOI: 10.1021/Acschembio.6B00995  0.318
2016 Brockman EC, Jackson TC, Dixon CE, Bayir H, Clark R, Vagni VA, Janesko KL, Byrd C, Ma L, Hsia CJ, Kochanek PM. POLYNITROXYLATED PEGYLATED HEMOGLOBIN: A NOVEL, SMALL VOLUME THERAPEUTIC FOR TRAUMATIC BRAIN INJURY RESUSCITATION: COMPARISON TO WHOLE BLOOD AND DOSE RESPONSE EVALUATION. Journal of Neurotrauma. PMID 27869558 DOI: 10.1089/neu.2016.4656  0.307
2016 Simon D, Aneja R, New L, Vagni V, Bayir H, Morowitz M, Kochanek P, Clark R. 743: ACUTE INFLAMMATORY RESPONSE TO TRAUMATIC BRAIN INJURY IS AFFECTED BY MODULATORS OF GUT MICROBIOTA. Critical Care Medicine. 44: 262. PMID 27850381 DOI: 10.1097/01.Ccm.0000509419.49574.44  0.381
2016 Kenny E, Yang Q, Fidan E, Ann New L, Anthonymuthu TS, Kochanek P, Kagan V, Bayir H. 740: INHIBITION OF FERROPTOSIS AS A NEUROPROTECTIVE STRATEGY FOLLOWING TRAUMATIC BRAIN INJURY. Critical Care Medicine. 44: 261. PMID 27850378 DOI: 10.1097/01.Ccm.0000509416.82747.8D  0.415
2016 Kagan VE, Mao G, Qu F, Angeli JP, Doll S, Croix CS, Dar HH, Liu B, Tyurin VA, Ritov VB, Kapralov AA, Amoscato AA, Jiang J, Anthonymuthu T, Mohammadyani D, et al. Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis. Nature Chemical Biology. PMID 27842066 DOI: 10.1038/Nchembio.2238  0.343
2016 Sparvero LJ, Amoscato AA, Fink AB, Anthonymuthu T, New LE, Kochanek PM, Watkins S, Kagan VE, Bayır H. Imaging Mass Spectrometry Reveals Loss of Polyunsaturated Cardiolipins in the Cortical Contusion, Hippocampus and Thalamus after Traumatic Brain Injury. Journal of Neurochemistry. PMID 27591733 DOI: 10.1111/Jnc.13840  0.449
2016 Dezfulian C, Kenny E, Lamade A, Misse A, Krehel N, St Croix C, Kelley EE, Jackson TC, Uray T, Rackley J, Kochanek PM, Clark RS, Bayir H. Mechanistic characterization of nitrite-mediated neuroprotection after experimental cardiac arrest. Journal of Neurochemistry. PMID 27507435 DOI: 10.1111/Jnc.13764  0.42
2016 Maguire JJ, Tyurina YY, Mohammadyani D, Kapralov AA, Anthonymuthu TS, Qu F, Amoscato AA, Sparvero LJ, Tyurin VA, Planas-Iglesias J, He RR, Klein-Seetharaman J, Bayır H, Kagan VE. Known unknowns of cardiolipin signaling: The best is yet to come. Biochimica Et Biophysica Acta. PMID 27498292 DOI: 10.1016/J.Bbalip.2016.08.001  0.325
2016 Hagos FT, Daood MJ, Ocque JA, Nolin TD, Bayir H, Poloyac SM, Kochanek PM, Clark RS, Empey PE. Probenecid, an organic anion transporter 1 and 3 inhibitor, increases plasma and brain exposure of N-acetylcysteine. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-8. PMID 27278858 DOI: 10.1080/00498254.2016.1187777  0.338
2016 Tejero J, Kapralov AA, Baumgartner MP, Sparacino-Watkins CE, Anthonymutu TS, Vlasova II, Camacho CJ, Gladwin MT, Bayir H, Kagan VE. Peroxidase activation of cytoglobin by anionic phospholipids: Mechanisms and consequences. Biochimica Et Biophysica Acta. PMID 26928591 DOI: 10.1016/J.Bbalip.2016.02.022  0.309
2016 Anthonymuthu TS, Kenny EM, Bayır H. Therapies targeting lipid peroxidation in traumatic brain injury. Brain Research. 1640: 57-76. PMID 26872597 DOI: 10.1016/J.Brainres.2016.02.006  0.428
2016 Du L, Empey P, Ji J, Chao H, Kochanek PM, Bayir H, Clark R. Probenecid and N-acetylcysteine Prevent Loss of Intracellular Glutathione and Inhibit Neuronal Death after Mechanical Stretch Injury In Vitro. Journal of Neurotrauma. PMID 26830358 DOI: 10.1089/Neu.2015.4342  0.537
2016 Huang Z, Epperly M, Watkins SC, Greenberger JS, Kagan VE, Bayır H. Necrostatin-1 rescues mice from lethal irradiation. Biochimica Et Biophysica Acta. PMID 26802452 DOI: 10.1016/J.Bbadis.2016.01.014  0.316
2016 Kagan VE, Jiang J, Huang Z, Tyurina YY, Desbourdes C, Cottet-Rousselle C, Dar HH, Verma M, Tyurin VA, Kapralov AA, Cheikhi A, Mao G, Stolz D, St Croix CM, Watkins S, et al. NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy. Cell Death and Differentiation. PMID 26742431 DOI: 10.1038/Cdd.2015.160  0.308
2016 Schlattner U, Jiang J, Huang Z, Tyurina YY, Desbourdes C, Cottet-Rousselle C, Dar H, Verma M, Tyurina VA, Kapralov AA, Lacombe M, Chu CT, Mallampalli R, Bayir H, Kagan VE. Mitochondrial NM23-H4/NDPK-D Supports Cardiolipin Signaling to Eliminate Depolarized Mitochondria by Mitophagy Biophysical Journal. 110: 472a. DOI: 10.1016/J.Bpj.2015.11.2528  0.306
2015 Greenberger J, Kagan V, Bayir H, Wipf P, Epperly M. Antioxidant Approaches to Management of Ionizing Irradiation Injury. Antioxidants (Basel, Switzerland). 4: 82-101. PMID 26785339 DOI: 10.3390/Antiox4010082  0.34
2015 Mao G, Qu F, St Croix CM, Tyurina YY, Planas-Iglesias J, Jiang J, Huang Z, Amoscato AA, Tyurin VA, Kapralov AA, Cheikhi A, Maguire J, Klein-Seetharaman J, Bayir H, Kagan VE. Mitochondrial Redox Opto-Lipidomics Reveals Mono-Oxygenated Cardiolipins as Pro-Apoptotic Death Signals. Acs Chemical Biology. PMID 26697918 DOI: 10.1021/Acschembio.5B00737  0.361
2015 Shein SL, Ferguson NM, Kochanek PM, Bayir H, Clark RS, Fink EL, Tyler-Kabara EC, Wisniewski SR, Tian Y, Balasubramani GK, Bell MJ. Effectiveness of Pharmacological Therapies for Intracranial Hypertension in Children With Severe Traumatic Brain Injury-Results From an Automated Data Collection System Time-Synched to Drug Administration. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. PMID 26673840 DOI: 10.1097/Pcc.0000000000000610  0.365
2015 Kochanek PM, Bayır H. Hidden Perils of the "Wild Blue Yonder" after Traumatic Brain Injury. Journal of Neurotrauma. PMID 26625357 DOI: 10.1089/Neu.2015.4329  0.411
2015 Newell E, Shellington DK, Simon DW, Bell MJ, Kochanek PM, Feldman K, Bayir H, Aneja RK, Carcillo JA, Clark RS. Cerebrospinal Fluid Markers of Macrophage and Lymphocyte Activation After Traumatic Brain Injury in Children. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 16: 549-57. PMID 25850867 DOI: 10.1097/Pcc.0000000000000400  0.41
2015 Robertson CL, Fidan E, Stanley RM, Noje C, Bayir H. Progesterone for neuroprotection in pediatric traumatic brain injury. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 16: 236-44. PMID 25581631 DOI: 10.1097/Pcc.0000000000000323  0.421
2015 Fidan E, Foley L, New L, Kochanek P, Hitchens TK, Bayir H. 18: In Vivo Metabolic and Structural Imaging at 7t After Mild Traumatic Brain Injury in Immature Rats Critical Care Medicine. 43: 5. DOI: 10.1097/01.Ccm.0000473846.89843.A0  0.361
2015 Kim-Campbell N, Krehel N, Drabek T, Gladwin M, Callaway C, Dezfulian C, Bayir H, Kochanek P. 9: Renal Injury Associated With Free Hemoglobin In Rat Cardiopulmonary Bypass Is Attenuated By Nitrite. Critical Care Medicine. 43: 3. DOI: 10.1097/01.Ccm.0000473837.77933.31  0.305
2015 Stoyanovsky D, Jiang J, Murphy M, Epperly M, Li S, Greenberger J, Kagan V, Bayir H. Mitigation of Irradiation Damage In Vitro and In Vivo by Mitochondrial Targeted Glutathione Peroxidase 4 Mimic Mito-Ebselen International Journal of Radiation Oncology*Biology*Physics. 93: E541. DOI: 10.1016/J.Ijrobp.2015.07.1933  0.306
2015 Bayir H, Epperly M, Fidan E, Wang H, Kagan V, Greenberger JS. Assessment of Inflammatory Markers After Total Body Irradiation Combined With Traumatic Brain Injury in Mice International Journal of Radiation Oncology Biology Physics. 93. DOI: 10.1016/J.Ijrobp.2015.07.1929  0.384
2014 Jiang J, Bakan A, Kapralov AA, Silva KI, Huang Z, Amoscato AA, Peterson J, Garapati VK, Saxena S, Bayir H, Atkinson J, Bahar I, Kagan VE. Designing inhibitors of cytochrome c/cardiolipin peroxidase complexes: mitochondria-targeted imidazole-substituted fatty acids. Free Radical Biology & Medicine. 71: 221-30. PMID 24631490 DOI: 10.1016/J.Freeradbiomed.2014.02.029  0.322
2014 Tyurina YY, Domingues RM, Tyurin VA, Maciel E, Domingues P, Amoscato AA, Bayir H, Kagan VE. Characterization of cardiolipins and their oxidation products by LC-MS analysis. Chemistry and Physics of Lipids. 179: 3-10. PMID 24333544 DOI: 10.1016/J.Chemphyslip.2013.12.003  0.324
2014 Kagan VE, Chu CT, Tyurina YY, Cheikhi A, Bayir H. Cardiolipin asymmetry, oxidation and signaling. Chemistry and Physics of Lipids. 179: 64-9. PMID 24300280 DOI: 10.1016/J.Chemphyslip.2013.11.010  0.331
2014 Hagos F, Ocque J, Nolin T, Poloyac S, Bayir H, Kochanek P, Clark R, Empey P. 627: Probenecid Increases N-Acetylcysteine Brain Levels Critical Care Medicine. 42. DOI: 10.1097/01.Ccm.0000458124.29933.D9  0.305
2014 Simon D, Aneja R, Lewis J, Alexander H, Bell M, Bayir H, Kochanek P, Clark R. 527: Minocycline Delays Recovery In A Model Of Pediatric Traumatic Brain Injury Critical Care Medicine. 42. DOI: 10.1097/01.Ccm.0000458024.61282.2C  0.4
2014 Amoscato AA, Sparvero LJ, He RR, Watkins S, Bayir H, Kagan VE. Imaging mass spectrometry of diversified cardiolipin molecular species in the brain Analytical Chemistry. 86: 6587-6595. DOI: 10.1021/Ac5011876  0.335
2013 Jackson TC, Verrier JD, Drabek T, Janesko-Feldman K, Gillespie DG, Uray T, Dezfulian C, Clark RS, Bayir H, Jackson EK, Kochanek PM. Pharmacological inhibition of pleckstrin homology domain leucine-rich repeat protein phosphatase is neuroprotective: differential effects on astrocytes. The Journal of Pharmacology and Experimental Therapeutics. 347: 516-28. PMID 24023368 DOI: 10.1124/Jpet.113.206888  0.342
2013 Simon D, Aneja R, Lewis J, Bayir H, Bell M, Kochanek P, Clark R. 10: Hmgb1 Translocation And Microglial Activation After Pediatric Tbi Attenuated By Minocycline Critical Care Medicine. 41. DOI: 10.1097/01.Ccm.0000439195.54340.48  0.384
2013 Dezfulian C, Misse A, Stezoski JP, Kochanek PM, Bayir H, Clark RS. P65: Nitrite after cardiac arrest has antioxidant effects reducing reperfusion cerebral hyperemia and subsequent caspase activation Nitric Oxide. 31. DOI: 10.1016/J.Niox.2013.02.067  0.339
2012 Su E, Bell MJ, Kochanek PM, Wisniewski SR, Bayir H, Clark RS, Adelson PD, Tyler-Kabara EC, Janesko-Feldman KL, Berger RP. Increased CSF concentrations of myelin basic protein after TBI in infants and children: absence of significant effect of therapeutic hypothermia. Neurocritical Care. 17: 401-7. PMID 22890910 DOI: 10.1007/S12028-012-9767-0  0.338
2012 Sparvero LJ, Amoscato AA, Dixon CE, Long JB, Kochanek PM, Pitt BR, Bayir H, Kagan VE. Mapping of phospholipids by MALDI imaging (MALDI-MSI): realities and expectations. Chemistry and Physics of Lipids. 165: 545-62. PMID 22692104 DOI: 10.1016/J.Chemphyslip.2012.06.001  0.33
2012 Au AK, Aneja RK, Bell MJ, Bayir H, Feldman K, Adelson PD, Fink EL, Kochanek PM, Clark RS. Cerebrospinal fluid levels of high-mobility group box 1 and cytochrome C predict outcome after pediatric traumatic brain injury. Journal of Neurotrauma. 29: 2013-21. PMID 22540160 DOI: 10.1089/Neu.2011.2171  0.36
2012 Samhan-Arias AK, Ji J, Demidova OM, Sparvero LJ, Feng W, Tyurin V, Tyurina YY, Epperly MW, Shvedova AA, Greenberger JS, Bayır H, Kagan VE, Amoscato AA. Oxidized phospholipids as biomarkers of tissue and cell damage with a focus on cardiolipin. Biochimica Et Biophysica Acta. 1818: 2413-23. PMID 22464971 DOI: 10.1016/J.Bbamem.2012.03.014  0.532
2012 Smith RL, Lin JC, Adelson PD, Kochanek PM, Fink EL, Wisniewski SR, Bayir H, Tyler-Kabara EC, Clark RS, Brown SD, Bell MJ. Relationship between hyperglycemia and outcome in children with severe traumatic brain injury. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 13: 85-91. PMID 21499170 DOI: 10.1097/Pcc.0B013E3182192C30  0.378
2012 Brockman E, Dixon C, Bayir H, Blasiole B, Clark R, Vagni V, Ma L, Hsia C, Kochanek P. 531: Polynitroxylated Pegylated Hemoglobin Attenuates Fluid Requirements And Brain Edema In Combined Traumatic Brain Injury Plus Hemorrhagic Shock In Mice Critical Care Medicine. 40: 1-328. DOI: 10.1097/01.Ccm.0000424749.78837.0B  0.397
2012 Shein S, Feldman K, Vagni V, Xu M, Brockman E, Bayir H, Clark R, Kochanek P. 198: Delayed Hyperthermia Exacerbates Experimental Traumatic Brain Injury Critical Care Medicine. 40: 1-328. DOI: 10.1097/01.Ccm.0000424418.75053.57  0.404
2011 Manole MD, Tehranian-DePasquale R, Du L, Bayir H, Kochanek PM, Clark RS. Unmasking sex-based disparity in neuronal metabolism. Current Pharmaceutical Design. 17: 3854-60. PMID 21933143 DOI: 10.2174/138161211798357737  0.361
2011 Belikova NA, Glumac AL, Kapralova V, Cheikhi A, Tyurina YY, Vagni VA, Kochanek PM, Kagan VE, Bayir H. A high-throughput screening assay of ascorbate in brain samples. Journal of Neuroscience Methods. 201: 185-90. PMID 21855575 DOI: 10.1016/J.Jneumeth.2011.08.001  0.332
2011 Garman RH, Jenkins LW, Switzer RC, Bauman RA, Tong LC, Swauger PV, Parks SA, Ritzel DV, Dixon CE, Clark RS, Bayir H, Kagan V, Jackson EK, Kochanek PM. Blast exposure in rats with body shielding is characterized primarily by diffuse axonal injury. Journal of Neurotrauma. 28: 947-59. PMID 21449683 DOI: 10.1089/Neu.2010.1540  0.346
2011 Wagner AK, Amin KB, Niyonkuru C, Postal BA, McCullough EH, Ozawa H, Dixon CE, Bayir H, Clark RS, Kochanek PM, Fabio A. CSF Bcl-2 and cytochrome C temporal profiles in outcome prediction for adults with severe TBI. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 1886-96. PMID 21448217 DOI: 10.1038/Jcbfm.2011.31  0.345
2011 Shellington DK, Du L, Wu X, Exo J, Vagni V, Ma L, Janesko-Feldman K, Clark RS, Bayir H, Dixon CE, Jenkins LW, Hsia CJ, Kochanek PM. Polynitroxylated pegylated hemoglobin: a novel neuroprotective hemoglobin for acute volume-limited fluid resuscitation after combined traumatic brain injury and hemorrhagic hypotension in mice. Critical Care Medicine. 39: 494-505. PMID 21169820 DOI: 10.1097/Ccm.0B013E318206B1Fa  0.411
2011 Smith CM, Adelson PD, Chang YF, Brown SD, Kochanek PM, Clark RS, Bayir H, Hinchberger J, Bell MJ. Brain-systemic temperature gradient is temperature-dependent in children with severe traumatic brain injury. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 12: 449-54. PMID 20711083 DOI: 10.1097/Pcc.0B013E3181F390Dd  0.332
2011 Exo J, Kochanek PM, Adelson PD, Greene S, Clark RS, Bayir H, Wisniewski SR, Bell MJ. Intracranial pressure-monitoring systems in children with traumatic brain injury: combining therapeutic and diagnostic tools. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 12: 560-5. PMID 20625341 DOI: 10.1097/Pcc.0B013E3181E8B3Ee  0.371
2010 Sparvero LJ, Amoscato AA, Kochanek PM, Pitt BR, Kagan VE, Bayir H. Mass-spectrometry based oxidative lipidomics and lipid imaging: applications in traumatic brain injury. Journal of Neurochemistry. 115: 1322-36. PMID 20950335 DOI: 10.1111/J.1471-4159.2010.07055.X  0.416
2010 Kochanek PM, Bayir H. Titrating oxygen during and after cardiopulmonary resuscitation. Jama. 303: 2190-1. PMID 20516423 DOI: 10.1001/Jama.2010.715  0.348
2010 Tyurin VA, Tyurina YY, Ritov VB, Lysytsya A, Amoscato AA, Kochanek PM, Hamilton R, Dekosky ST, Greenberger JS, Bayir H, Kagan VE. Oxidative lipidomics of apoptosis: quantitative assessment of phospholipid hydroperoxides in cells and tissues. Methods in Molecular Biology (Clifton, N.J.). 610: 353-74. PMID 20013189 DOI: 10.1007/978-1-60327-029-8_21  0.349
2010 Au AK, Bayir H, Kochanek PM, Clark RS. Evaluation of autophagy using mouse models of brain injury. Biochimica Et Biophysica Acta. 1802: 918-23. PMID 19879944 DOI: 10.1016/J.Bbadis.2009.10.010  0.441
2010 Tang M, Alexander H, Clark RS, Kochanek PM, Kagan VE, Bayir H. Minocycline reduces neuronal death and attenuates microglial response after pediatric asphyxial cardiac arrest. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 119-29. PMID 19756023 DOI: 10.1038/Jcbfm.2009.194  0.332
2009 Belikova NA, Glumac A, Rafikov R, Jiang J, Greenberger JS, Kagan VE, Bayir H. Radioprotection by short-term oxidative preconditioning: role of manganese superoxide dismutase. Febs Letters. 583: 3437-42. PMID 19822147 DOI: 10.1016/J.Febslet.2009.10.013  0.328
2009 Kagan VE, Wipf P, Stoyanovsky D, Greenberger JS, Borisenko G, Belikova NA, Yanamala N, Samhan Arias AK, Tungekar MA, Jiang J, Tyurina YY, Ji J, Klein-Seetharaman J, Pitt BR, Shvedova AA, ... Bayir H, et al. Mitochondrial targeting of electron scavenging antioxidants: Regulation of selective oxidation vs random chain reactions. Advanced Drug Delivery Reviews. 61: 1375-85. PMID 19716396 DOI: 10.1016/J.Addr.2009.06.008  0.515
2009 Exo JL, Shellington DK, Bayir H, Vagni VA, Janesco-Feldman K, Ma L, Hsia CJ, Clark RS, Jenkins LW, Dixon CE, Kochanek PM. Resuscitation of traumatic brain injury and hemorrhagic shock with polynitroxylated albumin, hextend, hypertonic saline, and lactated Ringer's: Effects on acute hemodynamics, survival, and neuronal death in mice. Journal of Neurotrauma. 26: 2403-8. PMID 19691424 DOI: 10.1089/Neu.2009.0980  0.358
2009 de Toledo JS, Adelson PD, Watson RS, Gaines B, Brown SD, Kochanek PM, Wisniewski SR, Fink E, Bayir H, Clark RS, Bell MJ. Relationship between increases in pancreatic enzymes and cerebral events in children after traumatic brain injury. Neurocritical Care. 11: 322-9. PMID 19669945 DOI: 10.1007/S12028-009-9265-1  0.374
2009 Foley LM, Hitchens TK, Ho C, Janesko-Feldman KL, Melick JA, Bayir H, Kochanek PM. Magnetic resonance imaging assessment of macrophage accumulation in mouse brain after experimental traumatic brain injury. Journal of Neurotrauma. 26: 1509-19. PMID 19663686 DOI: 10.1089/Neu.2008.0747  0.361
2009 Puccio AM, Hoffman LA, Bayir H, Zullo TG, Fischer M, Darby J, Alexander S, Dixon CE, Okonkwo DO, Kochanek PM. Effect of short periods of normobaric hyperoxia on local brain tissue oxygenation and cerebrospinal fluid oxidative stress markers in severe traumatic brain injury. Journal of Neurotrauma. 26: 1241-9. PMID 19505175 DOI: 10.1089/Neu.2008.0624  0.364
2009 Belikova NA, Jiang J, Stoyanovsky DA, Glumac A, Bayir H, Greenberger JS, Kagan VE. Mitochondria-targeted (2-hydroxyamino-vinyl)-triphenyl-phosphonium releases NO(.) and protects mouse embryonic cells against irradiation-induced apoptosis. Febs Letters. 583: 1945-50. PMID 19427865 DOI: 10.1016/J.Febslet.2009.04.050  0.359
2009 Bayir H, Kapralov AA, Jiang J, Huang Z, Tyurina YY, Tyurin VA, Zhao Q, Belikova NA, Vlasova II, Maeda A, Zhu J, Na HM, Mastroberardino PG, Sparvero LJ, Amoscato AA, et al. Peroxidase mechanism of lipid-dependent cross-linking of synuclein with cytochrome C: protection against apoptosis versus delayed oxidative stress in Parkinson disease. The Journal of Biological Chemistry. 284: 15951-69. PMID 19351880 DOI: 10.1074/Jbc.M900418200  0.334
2009 Tyurin VA, Tyurina YY, Jung MY, Tungekar MA, Wasserloos KJ, Bayir H, Greenberger JS, Kochanek PM, Shvedova AA, Pitt B, Kagan VE. Mass-spectrometric analysis of hydroperoxy- and hydroxy-derivatives of cardiolipin and phosphatidylserine in cells and tissues induced by pro-apoptotic and pro-inflammatory stimuli. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 877: 2863-72. PMID 19328050 DOI: 10.1016/J.Jchromb.2009.03.007  0.357
2009 Bayir H, Adelson PD, Wisniewski SR, Shore P, Lai Y, Brown D, Janesko-Feldman KL, Kagan VE, Kochanek PM. Therapeutic hypothermia preserves antioxidant defenses after severe traumatic brain injury in infants and children. Critical Care Medicine. 37: 689-95. PMID 19114918 DOI: 10.1097/CCM.0b013e318194abf2  0.33
2009 Kagan VE, Bayir A, Bayir H, Stoyanovsky D, Borisenko GG, Tyurina YY, Wipf P, Atkinson J, Greenberger JS, Chapkin RS, Belikova NA. Mitochondria-targeted disruptors and inhibitors of cytochrome c/cardiolipin peroxidase complexes: a new strategy in anti-apoptotic drug discovery. Molecular Nutrition & Food Research. 53: 104-14. PMID 18979502 DOI: 10.1002/Mnfr.200700402  0.355
2009 Dennis AM, Haselkorn ML, Vagni VA, Garman RH, Janesko-Feldman K, Bayir H, Clark RS, Jenkins LW, Dixon CE, Kochanek PM. Hemorrhagic shock after experimental traumatic brain injury in mice: effect on neuronal death. Journal of Neurotrauma. 26: 889-99. PMID 18781889 DOI: 10.1089/Neu.2008.0512  0.38
2008 Tyurin VA, Tyurina YY, Feng W, Mnuskin A, Jiang J, Tang M, Zhang X, Zhao Q, Kochanek PM, Clark RS, Bayir H, Kagan VE. Mass-spectrometric characterization of phospholipids and their primary peroxidation products in rat cortical neurons during staurosporine-induced apoptosis. Journal of Neurochemistry. 107: 1614-33. PMID 19014376 DOI: 10.1111/J.1471-4159.2008.05728.X  0.35
2008 Tyurin VA, Tyurina YY, Kochanek PM, Hamilton R, DeKosky ST, Greenberger JS, Bayir H, Kagan VE. Oxidative lipidomics of programmed cell death. Methods in Enzymology. 442: 375-93. PMID 18662580 DOI: 10.1016/S0076-6879(08)01419-5  0.378
2008 Han F, Drabek T, Stezoski J, Janesko-Feldman K, Stezoski SW, Clark RS, Bayir H, Tisherman SA, Kochanek PM. Protein nitration and poly-ADP-ribosylation in brain after rapid exsanguination cardiac arrest in a rat model of emergency preservation and resuscitation. Resuscitation. 79: 301-10. PMID 18640761 DOI: 10.1016/J.Resuscitation.2008.06.004  0.333
2008 Foley LM, Hitchens TK, Melick JA, Bayir H, Ho C, Kochanek PM. Effect of inducible nitric oxide synthase on cerebral blood flow after experimental traumatic brain injury in mice. Journal of Neurotrauma. 25: 299-310. PMID 18373480 DOI: 10.1089/Neu.2007.0471  0.434
2008 Bayir H, Kagan VE. Bench-to-bedside review: Mitochondrial injury, oxidative stress and apoptosis--there is nothing more practical than a good theory. Critical Care (London, England). 12: 206. PMID 18341705 DOI: 10.1186/Cc6779  0.433
2008 Clark RS, Bayir H, Chu CT, Alber SM, Kochanek PM, Watkins SC. Autophagy is increased in mice after traumatic brain injury and is detectable in human brain after trauma and critical illness. Autophagy. 4: 88-90. PMID 17957135 DOI: 10.4161/Auto.5173  0.438
2008 Lai Y, Hickey RW, Chen Y, Bayir H, Sullivan ML, Chu CT, Kochanek PM, Dixon CE, Jenkins LW, Graham SH, Watkins SC, Clark RS. Autophagy is increased after traumatic brain injury in mice and is partially inhibited by the antioxidant gamma-glutamylcysteinyl ethyl ester. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 540-50. PMID 17786151 DOI: 10.1038/Sj.Jcbfm.9600551  0.443
2007 Buttram SD, Wisniewski SR, Jackson EK, Adelson PD, Feldman K, Bayir H, Berger RP, Clark RS, Kochanek PM. Multiplex assessment of cytokine and chemokine levels in cerebrospinal fluid following severe pediatric traumatic brain injury: effects of moderate hypothermia. Journal of Neurotrauma. 24: 1707-17. PMID 18001201 DOI: 10.1089/Neu.2007.0349  0.321
2007 Bayir H, Tyurin VA, Tyurina YY, Viner R, Ritov V, Amoscato AA, Zhao Q, Zhang XJ, Janesko-Feldman KL, Alexander H, Basova LV, Clark RS, Kochanek PM, Kagan VE. Selective early cardiolipin peroxidation after traumatic brain injury: an oxidative lipidomics analysis. Annals of Neurology. 62: 154-69. PMID 17685468 DOI: 10.1002/Ana.21168  0.483
2007 Kagan VE, Jiang J, Bayir H, Stoyanovsky DA. Targeting nitroxides to mitochondria: location, location, location, and ...concentration: highlight commentary on "Mitochondria superoxide dismutase mimetic inhibits peroxide-induced oxidative damage and apoptosis: role of mitochondrial superoxide". Free Radical Biology & Medicine. 43: 348-50. PMID 17602949 DOI: 10.1016/J.Freeradbiomed.2007.03.030  0.338
2007 Bayir H, Kagan VE, Clark RS, Janesko-Feldman K, Rafikov R, Huang Z, Zhang X, Vagni V, Billiar TR, Kochanek PM. Neuronal NOS-mediated nitration and inactivation of manganese superoxide dismutase in brain after experimental and human brain injury. Journal of Neurochemistry. 101: 168-81. PMID 17394464 DOI: 10.1111/J.1471-4159.2006.04353.X  0.457
2007 Shore PM, Berger RP, Varma S, Janesko KL, Wisniewski SR, Clark RS, Adelson PD, Thomas NJ, Lai YC, Bayir H, Kochanek PM. Cerebrospinal fluid biomarkers versus glasgow coma scale and glasgow outcome scale in pediatric traumatic brain injury: the role of young age and inflicted injury. Journal of Neurotrauma. 24: 75-86. PMID 17263671 DOI: 10.1089/Neu.2006.0062  0.392
2007 Tyurina YY, Basova LV, Konduru NV, Tyurin VA, Potapovich AI, Cai P, Bayir H, Stoyanovsky D, Pitt BR, Shvedova AA, Fadeel B, Kagan VE. Nitrosative stress inhibits the aminophospholipid translocase resulting in phosphatidylserine externalization and macrophage engulfment: implications for the resolution of inflammation. The Journal of Biological Chemistry. 282: 8498-509. PMID 17229723 DOI: 10.1074/Jbc.M606950200  0.329
2006 Bayir H, Kochanek PM, Kagan VE. Oxidative stress in immature brain after traumatic brain injury. Developmental Neuroscience. 28: 420-31. PMID 16943665 DOI: 10.1159/000094168  0.439
2006 Cousar JL, Lai Y, Marco CD, Bayir H, Adelson PD, Janesko-Feldman KL, Kochanek PM, Clark RS. Heme oxygenase 1 in cerebrospinal fluid from infants and children after severe traumatic brain injury. Developmental Neuroscience. 28: 342-7. PMID 16943657 DOI: 10.1159/000094160  0.401
2006 Kagan VE, Tyurina YY, Bayir H, Chu CT, Kapralov AA, Vlasova II, Belikova NA, Tyurin VA, Amoscato A, Epperly M, Greenberger J, Dekosky S, Shvedova AA, Jiang J. The "pro-apoptotic genies" get out of mitochondria: oxidative lipidomics and redox activity of cytochrome c/cardiolipin complexes. Chemico-Biological Interactions. 163: 15-28. PMID 16797512 DOI: 10.1016/J.Cbi.2006.04.019  0.356
2006 Bayir H, Fadeel B, Palladino MJ, Witasp E, Kurnikov IV, Tyurina YY, Tyurin VA, Amoscato AA, Jiang J, Kochanek PM, DeKosky ST, Greenberger JS, Shvedova AA, Kagan VE. Apoptotic interactions of cytochrome c: redox flirting with anionic phospholipids within and outside of mitochondria. Biochimica Et Biophysica Acta. 1757: 648-59. PMID 16740248 DOI: 10.1016/J.Bbabio.2006.03.002  0.354
2005 Bayir H, Kagan VE, Borisenko GG, Tyurina YY, Janesko KL, Vagni VA, Billiar TR, Williams DL, Kochanek PM. Enhanced oxidative stress in iNOS-deficient mice after traumatic brain injury: support for a neuroprotective role of iNOS. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 673-84. PMID 15716856 DOI: 10.1038/Sj.Jcbfm.9600068  0.431
2005 Puccio AM, Walter KA, Bayir H, Kochanek PM, Hoffman LA, Kim Y. HUMAN CEREBROSPINAL OXIDATIVE STRESS MARKER RESPONSE FOLLOWING A NORMOBARIC HYPEROXIA TRIAL AFTER SEVERE TRAUMATIC BRAIN INJURY. Critical Care Medicine. 33: A102. DOI: 10.1097/00003246-200512002-00361  0.405
2005 Bayir H, Clark RS, Zhang XJ, Kagan VE, Feldman KL, Vagni V, Kochanek PM. Mechanisms Of Tyrosine Nitration Of Mnsod After Traumatic Brain Injury.: 61 Critical Care Medicine. 33. DOI: 10.1097/00003246-200512002-00061  0.376
2005 Buttram SD, Bayir H, Clark RS, Kochanek PM, Wisniewski SR, Adelson PD, Janesko-Feldman K, Jackson EK, Berger R. A COMPREHENSIVE ASSESSMENT OF THE CYTOKINE RESPONSE AFTER SEVERE PEDIATRIC TRAUMATIC BRAIN INJURY: EFFECTS OF MODERATE HYPOTHERMIA. Critical Care Medicine. 33: A3. DOI: 10.1097/00003246-200512002-00010  0.404
2004 Shore PM, Thomas NJ, Clark RS, Adelson PD, Wisniewski SR, Janesko KL, Bayir H, Jackson EK, Kochanek PM. Continuous versus intermittent cerebrospinal fluid drainage after severe traumatic brain injury in children: effect on biochemical markers. Journal of Neurotrauma. 21: 1113-22. PMID 15453982 DOI: 10.1089/Neu.2004.21.1113  0.349
2004 Du L, Bayir H, Lai Y, Zhang X, Kochanek PM, Watkins SC, Graham SH, Clark RS. Innate gender-based proclivity in response to cytotoxicity and programmed cell death pathway. The Journal of Biological Chemistry. 279: 38563-70. PMID 15234982 DOI: 10.1074/Jbc.M405461200  0.33
2004 Wagner AK, Bayir H, Ren D, Puccio A, Zafonte RD, Kochanek PM. Relationships between cerebrospinal fluid markers of excitotoxicity, ischemia, and oxidative damage after severe TBI: the impact of gender, age, and hypothermia. Journal of Neurotrauma. 21: 125-36. PMID 15000754 DOI: 10.1089/089771504322778596  0.394
2004 Bayir H, Marion DW, Puccio AM, Wisniewski SR, Janesko KL, Clark RS, Kochanek PM. Marked gender effect on lipid peroxidation after severe traumatic brain injury in adult patients. Journal of Neurotrauma. 21: 1-8. PMID 14987460 DOI: 10.1089/089771504772695896  0.4
2004 Bayir H, Zhang X, Clark RS, Kagan VE, Janesko KL, Du L, Vagni V, Kochanek PM. Nitration And Inactivation Of Mnsod After Experimental Cns Injury: Studies In Experimental Traumatic Brain Injury And Neuronal Culture: 87 Critical Care Medicine. 32. DOI: 10.1097/00003246-200412001-00087  0.393
2004 Fink EL, Bayir H, Lai Y, Chen Y, Zhang X, Alexander H, Kochanek PM, Clark RS. γ-GLUTAMYLCYSTEINE ETHYL ESTER INCREASES BRAIN GLUTATHIONE AFTER ASPHYXIAL CARDIAC ARREST IN POST-NATAL DAY 17 RATS: 86 Critical Care Medicine. 32. DOI: 10.1097/00003246-200412001-00086  0.305
2003 Varma S, Janesko KL, Wisniewski SR, Bayir H, Adelson PD, Thomas NJ, Kochanek PM. F2-isoprostane and neuron-specific enolase in cerebrospinal fluid after severe traumatic brain injury in infants and children. Journal of Neurotrauma. 20: 781-6. PMID 12965056 DOI: 10.1089/089771503767870005  0.38
2003 Bayir H, Kochanek PM, Clark RS. Traumatic brain injury in infants and children: mechanisms of secondary damage and treatment in the intensive care unit. Critical Care Clinics. 19: 529-49. PMID 12848319 DOI: 10.1016/S0749-0704(03)00014-9  0.339
2003 Bayir H, Clark RS, Kochanek PM. Promising strategies to minimize secondary brain injury after head trauma. Critical Care Medicine. 31: S112-7. PMID 12544985 DOI: 10.1097/00003246-200301001-00016  0.418
2003 Bayir H, Kochanek PM, Liu SX, Arroyo A, Osipov A, Jiang J, Wisniewski S, Adelson PD, Graham SH, Kagan VE. Increased S-nitrosothiols and S-nitrosoalbumin in cerebrospinal fluid after severe traumatic brain injury in infants and children: indirect association with intracranial pressure. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 51-61. PMID 12500091 DOI: 10.1097/01.Wcb.0000040399.30600.E3  0.371
2002 Ruppel RA, Clark RS, Bayir H, Satchell MA, Kochanek PM. Critical mechanisms of secondary damage after inflicted head injury in infants and children. Neurosurgery Clinics of North America. 13: 169-82, v. PMID 12391702 DOI: 10.1016/S1042-3680(01)00005-5  0.387
2002 Bayir H, Kagan VE, Tyurina YY, Tyurin V, Ruppel RA, Adelson PD, Graham SH, Janesko K, Clark RS, Kochanek PM. Assessment of antioxidant reserves and oxidative stress in cerebrospinal fluid after severe traumatic brain injury in infants and children. Pediatric Research. 51: 571-8. PMID 11978879 DOI: 10.1203/00006450-200205000-00005  0.373
2002 Bayir H, Janesko KL, Kochanek PM. Therapeutic Hypothermia Attenuates Oxidative Stress After Traumatic Brain Injury In Infants And Children: 27 Critical Care Medicine. 30. DOI: 10.1097/00003246-200212001-00027  0.399
2002 Lai Y, Kochanek PM, Shore PM, Janesko K, Bayir H, Clark RS. Age-Related Increase In Protein Kinase B (Akt) After Pediatric Traumatic Brain Injury: 26 Critical Care Medicine. 30. DOI: 10.1097/00003246-200212001-00026  0.363
2002 Shore PM, Adelson PD, Bayir H. Continuous Vs Intermittent Cerebrospinal Fluid Drainage After Severe Traumatic Brain Injury In Children: Effect On Biochemical Markers: 25 Critical Care Medicine. 30. DOI: 10.1097/00003246-200212001-00025  0.393
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