Gabsang Lee, D.V.M., Ph.D. - Publications

Neurology Johns Hopkins University School of Medicine, Baltimore, MD, United States 

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Lim H, Choi IY, Hyun SH, Kim H, Lee G. Approaches to characterize the transcriptional trajectory of human myogenesis. Cellular and Molecular Life Sciences : Cmls. PMID 33590269 DOI: 10.1007/s00018-021-03782-1  1
2020 Choi IY, Lim H, Huynh A, Schofield J, Cho HJ, Lee H, Andersen P, Shin JH, Heo WD, Hyun SH, Kim YJ, Oh Y, Kim H, Lee G. Novel culture system via wirelessly controllable optical stimulation of the FGF signaling pathway for human and pig pluripotency. Biomaterials. 120222. PMID 32736809 DOI: 10.1016/j.biomaterials.2020.120222  1
2020 Sun C, Choi IY, Rovira Gonzalez YI, Andersen P, Talbot CC, Iyer SR, Lovering RM, Wagner KR, Lee G. Duchenne muscular dystrophy hiPSC-derived myoblast drug screen identifies compounds that ameliorate disease in mdx mice. Jci Insight. PMID 32343677 DOI: 10.1172/jci.insight.134287  0.64
2020 Kim GS, Kim SM, Kim SU, Lee G, Choi KC. Inhibitory effect of therapeutic genes, cytosine deaminase and interferon‑β, delivered by genetically engineered stem cells against renal cell carcinoma. Oncology Reports. PMID 32236604 DOI: 10.3892/or.2020.7570  0.6
2020 Choi IY, Lim H, Cho HJ, Oh Y, Chou BK, Bai H, Cheng L, Kim YJ, Hyun S, Kim H, Shin JH, Lee G. Transcriptional landscape of myogenesis from human pluripotent stem cells reveals a key role of TWIST1 in maintenance of skeletal muscle progenitors. Elife. 9. PMID 32011235 DOI: 10.7554/eLife.46981  1
2019 Kim S, Kwon SH, Kam TI, Panicker N, Karuppagounder SS, Lee S, Lee JH, Kim WR, Kook M, Foss CA, Shen C, Lee H, Kulkarni S, Pasricha PJ, Lee G, et al. Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson's Disease. Neuron. PMID 31255487 DOI: 10.1016/j.neuron.2019.05.035  0.4
2019 Mukherjee-Clavin B, Mi R, Kern B, Choi IY, Lim H, Oh Y, Lannon B, Kim KJ, Bell S, Hur JK, Hwang W, Che YH, Habib O, Baloh RH, Eggan K, ... ... Lee G, et al. Comparison of three congruent patient-specific cell types for the modelling of a human genetic Schwann-cell disorder. Nature Biomedical Engineering. PMID 30962586 DOI: 10.1038/s41551-019-0381-8  1
2019 Yoon JD, Hwang SU, Kim M, Lee G, Jeon Y, Hyun SH. GDF8 enhances SOX2 expression and blastocyst total cell number in porcine IVF embryo development. Theriogenology. 129: 70-76. PMID 30825707 DOI: 10.1016/j.theriogenology.2019.02.007  0.64
2019 Ayala-Cuellar AP, Kim CW, Hwang KA, Kang JH, Lee G, Cho J, Choi KC. Characterization of canine adipose tissue-derived mesenchymal stem cells immortalized by SV40-T retrovirus for therapeutic use. Journal of Cellular Physiology. PMID 30779347 DOI: 10.1002/jcp.28338  0.6
2019 Kim E, Kim M, Hwang SU, Kim J, Lee G, Park YS, Hyun SH. Neural induction of porcine-induced pluripotent stem cells and further differentiation using glioblastoma-cultured medium. Journal of Cellular and Molecular Medicine. PMID 30609263 DOI: 10.1111/jcmm.14111  0.64
2018 Kim E, Hwang SU, Yoon JD, Kim H, Lee G, Hyun SH. Isolation and characterization of GFAP-positive porcine neural stem/progenitor cells derived from a GFAP-CreER transgenic piglet. Bmc Veterinary Research. 14: 331. PMID 30404643 DOI: 10.1186/s12917-018-1660-4  1
2018 Hwang SU, Kim KJ, Kim E, Yoon JD, Park KM, Jin M, Han Y, Kim M, Lee G, Hyun SH. Lysophosphatidic acid increases in vitro maturation efficiency via uPA-uPAR signaling pathway in cumulus cells. Theriogenology. 113: 197-207. PMID 29554602 DOI: 10.1016/j.theriogenology.2018.02.020  0.64
2018 Kim S, Yun SP, Lee S, Umanah GE, Bandaru VVR, Yin X, Rhee P, Karuppagounder SS, Kwon SH, Lee H, Mao X, Kim D, Pandey A, Lee G, Dawson VL, et al. GBA1 deficiency negatively affects physiological α-synuclein tetramers and related multimers. Proceedings of the National Academy of Sciences of the United States of America. PMID 29311330 DOI: 10.1073/pnas.1700465115  0.4
2017 Oh Y, Zhang F, Wang Y, Lee EM, Choi IY, Lim H, Mirakhori F, Li R, Huang L, Xu T, Wu H, Li C, Qin CF, Wen Z, Wu QF, ... ... Lee G, et al. Zika virus directly infects peripheral neurons and induces cell death. Nature Neuroscience. PMID 28758997 DOI: 10.1038/nn.4612  0.64
2017 Kurapati S, Sadaoka T, Rajbhandari L, Jagdish B, Shukla P, Kim YJ, Lee G, Cohen JI, Venkatesan A. Role of JNK pathway in varicella-zoster virus lytic infection and reactivation. Journal of Virology. PMID 28637759 DOI: 10.1128/JVI.00640-17  0.4
2016 Zeltner N, Fattahi F, Dubois NC, Saurat N, Lafaille F, Shang L, Zimmer B, Tchieu J, Soliman MA, Lee G, Casanova JL, Studer L. Capturing the biology of disease severity in a PSC-based model of familial dysautonomia. Nature Medicine. PMID 27841875 DOI: 10.1038/nm.4220  1
2016 Nguyen TT, Park WS, Park BO, Kim CY, Oh Y, Kim JM, Choi H, Kyung T, Kim CH, Lee G, Hahn KM, Meyer T, Heo WD. PLEKHG3 enhances polarized cell migration by activating actin filaments at the cell front. Proceedings of the National Academy of Sciences of the United States of America. PMID 27555588 DOI: 10.1073/pnas.1604720113  0.44
2016 Nyffeler J, Karreman C, Leisner H, Kim YJ, Lee G, Waldmann T, Leist M. Design of a high-throughput human neural crest cell migration assay to indicate potential developmental toxicants. Altex. PMID 27463612 DOI: 10.14573/altex.1605031  0.4
2016 Oh Y, Cho GS, Li Z, Hong I, Zhu R, Kim MJ, Kim YJ, Tampakakis E, Tung L, Huganir R, Dong X, Kwon C, Lee G. Functional Coupling with Cardiac Muscle Promotes Maturation of hPSC-Derived Sympathetic Neurons. Cell Stem Cell. PMID 27320040 DOI: 10.1016/j.stem.2016.05.002  0.44
2016 Choi IY, Lim H, Estrellas K, Mula J, Cohen TV, Zhang Y, Donnelly CJ, Richard JP, Kim YJ, Kim H, Kazuki Y, Oshimura M, Li HL, Hotta A, Rothstein J, ... ... Lee G, et al. Concordant but Varied Phenotypes among Duchenne Muscular Dystrophy Patient-Specific Myoblasts Derived using a Human iPSC-Based Model. Cell Reports. PMID 27239027 DOI: 10.1016/j.celrep.2016.05.016  1
2016 Smith AS, Davis J, Lee G, Mack DL, Kim DH. Muscular dystrophy in a dish: engineered human skeletal muscle mimetics for disease modeling and drug discovery. Drug Discovery Today. PMID 27109386 DOI: 10.1016/j.drudis.2016.04.013  1
2015 Laguesse S, Creppe C, Nedialkova DD, Prévot PP, Borgs L, Huysseune S, Franco B, Duysens G, Krusy N, Lee G, Thelen N, Thiry M, Close P, Chariot A, Malgrange B, et al. A Dynamic Unfolded Protein Response Contributes to the Control of Cortical Neurogenesis. Developmental Cell. 35: 553-567. PMID 26651292 DOI: 10.1016/j.devcel.2015.11.005  1
2015 Choi J, Lee S, Mallard W, Clement K, Tagliazucchi GM, Lim H, Choi IY, Ferrari F, Tsankov AM, Pop R, Lee G, Rinn JL, Meissner A, Park PJ, Hochedlinger K. A comparison of genetically matched cell lines reveals the equivalence of human iPSCs and ESCs. Nature Biotechnology. PMID 26501951 DOI: 10.1038/nbt.3388  1
2015 Kim YJ, Lee G. Cellular stage specific functional analysis of REX1: In human embryonic stem cells. Proteomics. 15: 2147-9. PMID 26058466 DOI: 10.1002/pmic.201500208  1
2014 Kim YJ, Lim H, Li Z, Oh Y, Kovlyagina I, Choi IY, Dong X, Lee G. Generation of multipotent induced neural crest by direct reprogramming of human postnatal fibroblasts with a single transcription factor. Cell Stem Cell. 15: 497-506. PMID 25158936 DOI: 10.1016/j.stem.2014.07.013  1
2014 Lim H, Choi IY, Lee G. Profiling individual human embryonic stem cells by quantitative rt-PCR. Journal of Visualized Experiments : Jove. PMID 24961819 DOI: 10.3791/51408  1
2014 Choi IY, Lim H, Lee G. Efficient generation human induced pluripotent stem cells from human somatic cells with Sendai-virus. Journal of Visualized Experiments : Jove. PMID 24798302 DOI: 10.3791/51406  1
2013 Chambers SM, Mica Y, Lee G, Studer L, Tomishima MJ. Dual-SMAD Inhibition/WNT Activation-Based Methods to Induce Neural Crest and Derivatives from Human Pluripotent Stem Cells. Methods in Molecular Biology (Clifton, N.J.). PMID 24301074 DOI: 10.1007/7651_2013_59  1
2013 Kim YJ, Lee G. Candidate ALS therapeutics motor toward "in vitro clinical trials". Cell Stem Cell. 12: 633-4. PMID 23746968 DOI: 10.1016/j.stem.2013.05.009  1
2013 Mica Y, Lee G, Chambers SM, Tomishima MJ, Studer L. Modeling neural crest induction, melanocyte specification, and disease-related pigmentation defects in hESCs and patient-specific iPSCs. Cell Reports. 3: 1140-52. PMID 23583175 DOI: 10.1016/j.celrep.2013.03.025  1
2013 Mukherjee-Clavin B, Tomishima M, Lee G. Current approaches for efficient genetic editing in human pluripotent stem cells Frontiers in Biology. 8: 461-467. DOI: 10.1007/s11515-013-1275-x  1
2012 Lee G, Ramirez CN, Kim H, Zeltner N, Liu B, Radu C, Bhinder B, Kim YJ, Choi IY, Mukherjee-Clavin B, Djaballah H, Studer L. Large-scale screening using familial dysautonomia induced pluripotent stem cells identifies compounds that rescue IKBKAP expression. Nature Biotechnology. 30: 1244-8. PMID 23159879 DOI: 10.1038/nbt.2435  1
2012 Chambers SM, Qi Y, Mica Y, Lee G, Zhang XJ, Niu L, Bilsland J, Cao L, Stevens E, Whiting P, Shi SH, Studer L. Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors. Nature Biotechnology. 30: 715-20. PMID 22750882 DOI: 10.1038/nbt.2249  1
2012 Zimmer B, Lee G, Balmer NV, Meganathan K, Sachinidis A, Studer L, Leist M. Evaluation of developmental toxicants and signaling pathways in a functional test based on the migration of human neural crest cells. Environmental Health Perspectives. 120: 1116-22. PMID 22571897 DOI: 10.1289/ehp.1104489  1
2011 Lee G, Studer L. Modelling familial dysautonomia in human induced pluripotent stem cells. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 366: 2286-96. PMID 21727134 DOI: 10.1098/rstb.2011.0026  1
2011 Kim H, Lee G, Ganat Y, Papapetrou EP, Lipchina I, Socci ND, Sadelain M, Studer L. miR-371-3 expression predicts neural differentiation propensity in human pluripotent stem cells. Cell Stem Cell. 8: 695-706. PMID 21624813 DOI: 10.1016/j.stem.2011.04.002  1
2011 Papapetrou EP, Lee G, Malani N, Setty M, Riviere I, Tirunagari LM, Kadota K, Roth SL, Giardina P, Viale A, Leslie C, Bushman FD, Studer L, Sadelain M. Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells. Nature Biotechnology. 29: 73-8. PMID 21151124 DOI: 10.1038/nbt.1717  1
2010 Fasano CA, Chambers SM, Lee G, Tomishima MJ, Studer L. Efficient derivation of functional floor plate tissue from human embryonic stem cells. Cell Stem Cell. 6: 336-47. PMID 20362538 DOI: 10.1016/j.stem.2010.03.001  1
2010 Lee G, Chambers SM, Tomishima MJ, Studer L. Derivation of neural crest cells from human pluripotent stem cells. Nature Protocols. 5: 688-701. PMID 20360764 DOI: 10.1038/nprot.2010.35  1
2010 James D, Nam HS, Seandel M, Nolan D, Janovitz T, Tomishima M, Studer L, Lee G, Lyden D, Benezra R, Zaninovic N, Rosenwaks Z, Rabbany SY, Rafii S. Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent. Nature Biotechnology. 28: 161-6. PMID 20081865 DOI: 10.1038/nbt.1605  1
2010 Lee G, Studer L. Induced pluripotent stem cell technology for the study of human disease. Nature Methods. 7: 25-7. PMID 20038952 DOI: 10.1038/nmeth.f.283  1
2009 Lee G, Papapetrou EP, Kim H, Chambers SM, Tomishima MJ, Fasano CA, Ganat YM, Menon J, Shimizu F, Viale A, Tabar V, Sadelain M, Studer L. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature. 461: 402-6. PMID 19693009 DOI: 10.1038/nature08320  1
2008 Desbordes SC, Placantonakis DG, Ciro A, Socci ND, Lee G, Djaballah H, Studer L. High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell Stem Cell. 2: 602-12. PMID 18522853 DOI: 10.1016/j.stem.2008.05.010  1
2008 Kang HK, Roh S, Lee G, Hong SD, Kang H, Min BM. Osteogenic potential of embryonic stem cells in tooth sockets. International Journal of Molecular Medicine. 21: 539-44. PMID 18425344  1
2008 Lee G, Kim H, Elkabetz Y, Al Shamy G, Panagiotakos G, Barberi T, Tabar V, Studer L. Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells (Nature Biotechnology (2007) 25 (1468-1475)) Nature Biotechnology. 26: 831. DOI: 10.1038/nbt0708-831b  1
2007 Lee G, Kim H, Elkabetz Y, Al Shamy G, Panagiotakos G, Barberi T, Tabar V, Studer L. Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells. Nature Biotechnology. 25: 1468-75. PMID 18037878 DOI: 10.1038/nbt1365  1
2006 Moore MA, Shieh JH, Lee G. Hematopoietic cells. Methods in Enzymology. 418: 208-42. PMID 17141038 DOI: 10.1016/S0076-6879(06)18013-1  1
2003 Hyun S, Lee G, Kim D, Kim H, Lee S, Nam D, Jeong Y, Kim S, Yeom S, Kang S, Han J, Lee B, Hwang W. Production of nuclear transfer-derived piglets using porcine fetal fibroblasts transfected with the enhanced green fluorescent protein. Biology of Reproduction. 69: 1060-8. PMID 12773429 DOI: 10.1095/biolreprod.102.014886  1
2003 Hyun S, Lee B, Lee G, Lee E, Lim J, Kang S, Hwang W. Recruit of porcine oocytes excluded from nuclear transfer program for the production of embryos following parthenogenetic activation. The Journal of Veterinary Medical Science / the Japanese Society of Veterinary Science. 65: 51-6. PMID 12576704  0.4
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