Sreeganga S. Chandra, Ph.D. - Publications

Affiliations: 
Neurology Yale University, New Haven, CT 
Area:
Neurodegeneration, alpha-synuclein
Website:
http://tools.medicine.yale.edu/Chandra/www/

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Vidyadhara DJ, Bäckström D, Chakraborty R, Ruan J, Park JM, Mistry PK, Chandra SS. Synaptic vesicle endocytosis deficits underlie GBA-linked cognitive dysfunction in Parkinson's disease and Dementia with Lewy bodies. Biorxiv : the Preprint Server For Biology. PMID 39484386 DOI: 10.1101/2024.10.23.619548  0.394
2024 Zhu B, Park JM, Coffey SR, Russo A, Hsu IU, Wang J, Su C, Chang R, Lam TT, Gopal PP, Ginsberg SD, Zhao H, Hafler DA, Chandra SS, Zhang L. Single-cell transcriptomic and proteomic analysis of Parkinson's disease brains. Science Translational Medicine. 16: eabo1997. PMID 39475571 DOI: 10.1126/scitranslmed.abo1997  0.367
2024 Wang N, Zhu B, Allnutt MA, Grijalva RM, Zhao H, Chandra SS. Decoding transcriptomic signatures of cysteine string protein alpha-mediated synapse maintenance. Proceedings of the National Academy of Sciences of the United States of America. 121: e2320064121. PMID 38833477 DOI: 10.1073/pnas.2320064121  0.382
2023 Wang N, Zhu B, Allnutt MA, Grijalva RM, Zhao H, Chandra SS. Decoding transcriptomic signatures of Cysteine String Protein alpha-mediated synapse maintenance. Biorxiv : the Preprint Server For Biology. PMID 37873460 DOI: 10.1101/2023.10.02.560611  0.385
2023 Cheng X, Tang Y, Vidyadhara DJ, Li BZ, Zimmerman M, Pak A, Nareddula S, Edens PA, Chandra SS, Chubykin AA. Impaired pre-synaptic plasticity and visual responses in auxilin-knockout mice. Iscience. 26: 107842. PMID 37766983 DOI: 10.1016/j.isci.2023.107842  0.752
2023 Vargas KJ, Colosi PL, Girardi E, Park JM, Harmon LE, Chandra SS. α-Synuclein colocalizes with AP180 and affects the size of clathrin lattices. The Journal of Biological Chemistry. 105091. PMID 37516240 DOI: 10.1016/j.jbc.2023.105091  0.764
2023 Vidyadhara DJ, Somayaji M, Wade N, Yücel B, Zhao H, Shashaank N, Ribaudo J, Gupta J, Lam TT, Sames D, Greene LE, Sulzer DL, Chandra SS. Dopamine transporter and synaptic vesicle sorting defects underlie auxilin-associated Parkinson's disease. Cell Reports. 42: 112231. PMID 36920906 DOI: 10.1016/j.celrep.2023.112231  0.783
2023 Martin-Lopez E, Vidyadhara DJ, Liberia T, Meller SJ, Harmon LE, Hsu RM, Spence N, Brennan B, Han K, Yücel B, Chandra SS, Greer CA. α-Synuclein Pathology and Reduced Neurogenesis in the Olfactory System Affect Olfaction in a Mouse Model of Parkinson's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 36596700 DOI: 10.1523/JNEUROSCI.1526-22.2022  0.758
2022 Cunningham MJ, Bock HA, Serrano IC, Bechand B, Vidyadhara DJ, Bonniwell EM, Lankri D, Duggan P, Nazarova AL, Cao AB, Calkins MM, Khirsariya P, Hwu C, Katritch V, Chandra SS, et al. Pharmacological Mechanism of the Non-hallucinogenic 5-HT Agonist Ariadne and Analogs. Acs Chemical Neuroscience. PMID 36521179 DOI: 10.1021/acschemneuro.2c00597  0.71
2022 Massaro Tieze S, Chandra SS, Vidyadhara DJ. Subcellular Fractionation for the Isolation of Synaptic Components from the Murine Brain. Journal of Visualized Experiments : Jove. PMID 36190269 DOI: 10.3791/64574  0.753
2022 Gorenberg EL, Massaro Tieze S, Yücel B, Zhao HR, Chou V, Wirak GS, Tomita S, Lam TT, Chandra SS. Identification of substrates of palmitoyl protein thioesterase 1 highlights roles of depalmitoylation in disulfide bond formation and synaptic function. Plos Biology. 20: e3001590. PMID 35358180 DOI: 10.1371/journal.pbio.3001590  0.32
2019 Taguchi YV, Gorenberg EL, Nagy M, Thrasher D, Fenton WA, Volpicelli-Daley L, Horwich AL, Chandra SS. Hsp110 mitigates α-synuclein pathology in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 31685606 DOI: 10.1073/Pnas.1903268116  0.426
2019 Imler E, Pyon JS, Kindelay S, Torvund M, Zhang YQ, Chandra SS, Zinsmaier KE. A model of neuronal ceroid lipofuscinosis reveals a hypermorphic gain of function mechanism. Elife. 8. PMID 31663851 DOI: 10.7554/Elife.46607  0.397
2019 Vidyadhara DJ, Lee JE, Chandra SS. Role of the Endolysosomal System in Parkinson's disease. Journal of Neurochemistry. PMID 31287913 DOI: 10.1111/Jnc.14820  0.773
2017 Taguchi YV, Liu J, Ruan J, Pacheco J, Zhang X, Abbasi J, Keutzer J, Mistry PK, Chandra SS. Glucosylsphingosine promotes α-synuclein pathology in mutant GBA-associated Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28847804 DOI: 10.1523/Jneurosci.1525-17.2017  0.501
2017 Gorenberg EL, Chandra SS. The Role of Co-chaperones in Synaptic Proteostasis and Neurodegenerative Disease. Frontiers in Neuroscience. 11: 248. PMID 28579939 DOI: 10.3389/Fnins.2017.00248  0.518
2017 Vargas KJ, Schrod N, Davis T, Fernandez-Busnadiego R, Taguchi YV, Laugks U, Lucic V, Chandra SS. Synucleins Have Multiple Effects on Presynaptic Architecture. Cell Reports. 18: 161-173. PMID 28052246 DOI: 10.1016/J.Celrep.2016.12.023  0.796
2017 Taguchi YV, Liu J, Ruan J, Pacheco J, Zhang X, Abbasi J, Keutzer J, Mistry PK, Chandra SS. Glucosylsphingosine accelerates α-synuclein pathology in GBA-associated Parkinson disease Molecular Genetics and Metabolism. 120. DOI: 10.1016/J.Ymgme.2016.11.338  0.423
2015 Henderson MX, Wirak GS, Zhang YQ, Dai F, Ginsberg SD, Dolzhanskaya N, Staropoli JF, Nijssen PC, Lam TT, Roth AF, Davis NG, Dawson G, Velinov M, Chandra SS. Neuronal ceroid lipofuscinosis with DNAJC5/CSPα mutation has PPT1 pathology and exhibit aberrant protein palmitoylation. Acta Neuropathologica. PMID 26659577 DOI: 10.1007/S00401-015-1512-2  0.728
2014 Zhang YQ, Chandra SS. Oligomerization of Cysteine String Protein alpha mutants causing adult neuronal ceroid lipofuscinosis. Biochimica Et Biophysica Acta. 1842: 2136-46. PMID 25064588 DOI: 10.1016/J.Bbadis.2014.07.009  0.388
2014 Vargas KJ, Makani S, Davis T, Westphal CH, Castillo PE, Chandra SS. Synucleins regulate the kinetics of synaptic vesicle endocytosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 9364-76. PMID 25009269 DOI: 10.1523/Jneurosci.4787-13.2014  0.756
2013 Bilguvar K, Tyagi NK, Ozkara C, Tuysuz B, Bakircioglu M, Choi M, Delil S, Caglayan AO, Baranoski JF, Erturk O, Yalcinkaya C, Karacorlu M, Dincer A, Johnson MH, Mane S, ... Chandra SS, et al. Recessive loss of function of the neuronal ubiquitin hydrolase UCHL1 leads to early-onset progressive neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 110: 3489-94. PMID 23359680 DOI: 10.1073/Pnas.1222732110  0.35
2013 Westphal CH, Chandra SS. Monomeric synucleins generate membrane curvature. The Journal of Biological Chemistry. 288: 1829-40. PMID 23184946 DOI: 10.1074/Jbc.M112.418871  0.721
2012 Zhang YQ, Henderson MX, Colangelo CM, Ginsberg SD, Bruce C, Wu T, Chandra SS. Identification of CSPα clients reveals a role in dynamin 1 regulation. Neuron. 74: 136-50. PMID 22500636 DOI: 10.1016/J.Neuron.2012.01.029  0.753
2011 Anwar S, Peters O, Millership S, Ninkina N, Doig N, Connor-Robson N, Threlfell S, Kooner G, Deacon RM, Bannerman DM, Bolam JP, Chandra SS, Cragg SJ, Wade-Martins R, Buchman VL. Functional alterations to the nigrostriatal system in mice lacking all three members of the synuclein family. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7264-74. PMID 21593311 DOI: 10.1523/Jneurosci.6194-10.2011  0.419
2010 Greten-Harrison B, Polydoro M, Morimoto-Tomita M, Diao L, Williams AM, Nie EH, Makani S, Tian N, Castillo PE, Buchman VL, Chandra SS. αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction. Proceedings of the National Academy of Sciences of the United States of America. 107: 19573-8. PMID 20974939 DOI: 10.1073/Pnas.1005005107  0.507
2003 Chandra S, Chen X, Rizo J, Jahn R, Sudhof T. Backbone Assignments of folded alpha-synuclein Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr5744  0.426
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