Stephen C. Ekker, Ph.D. - Publications

Mayo Clinic, Rochester, MN, United States 

138 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Simone BW, Lee HB, Daby CL, Ata H, Restrepo-Castillo S, Martínez-Gálvez G, Kar B, Gendron WAC, Clark KJ, Ekker SC. Chimeric RNA:DNA TracrRNA Improves Homology-Directed Repair and . The Crispr Journal. PMID 34935462 DOI: 10.1089/crispr.2021.0087  0.737
2021 Sabharwal A, Kar B, Restrepo-Castillo S, Holmberg SR, Mathew ND, Kendall BL, Cotter RP, WareJoncas Z, Seiler C, Nakamaru-Ogiso E, Clark KJ, Ekker SC. The FusX TALE Base Editor (FusXTBE) for Rapid Mitochondrial DNA Programming of Human Cells and Zebrafish Disease Models . The Crispr Journal. 4: 799-821. PMID 34847747 DOI: 10.1089/crispr.2021.0061  0.611
2021 Welker JM, Wierson WA, Almeida MP, Mann CM, Torrie ME, Ming Z, Ekker SC, Clark KJ, Dobbs DL, Essner JJ, McGrail M. GeneWeld: Efficient Targeted Integration Directed by Short Homology in Zebrafish. Bio-Protocol. 11: e4100. PMID 34395736 DOI: 10.21769/BioProtoc.4100  0.621
2021 Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, Liu DR, Murray SA, Tsai SQ, Wilson RC, Anderson DG, Asokan A, Banfield JF, Bankiewicz KS, Bao G, Bulte JWM, ... ... Ekker SC, et al. The NIH Somatic Cell Genome Editing program. Nature. 592: 195-204. PMID 33828315 DOI: 10.1038/s41586-021-03191-1  0.607
2021 Almeida MP, Welker JM, Siddiqui S, Luiken J, Ekker SC, Clark KJ, Essner JJ, McGrail M. Endogenous zebrafish proneural Cre drivers generated by CRISPR/Cas9 short homology directed targeted integration. Scientific Reports. 11: 1732. PMID 33462297 DOI: 10.1038/s41598-021-81239-y  0.617
2020 Koleilat A, Dugdale JA, Christenson TA, Bellah JL, Lambert AM, Masino MA, Ekker SC, Schimmenti LA. L-type voltage-gated calcium channel agonists mitigate hearing loss and modify ribbon synapse morphology in the zebrafish model of Usher syndrome type 1 Disease Models & Mechanisms. 13. PMID 33361086 DOI: 10.1242/dmm.043885  0.64
2020 Koleilat A, Argue DP, Schimmenti LA, Ekker SC, Poling GL. The GoAudio Quantitative Mobile Audiology Test Enhances Access to Clinical Hearing Assessments. American Journal of Audiology. 1-11. PMID 33079580 DOI: 10.1044/2020_AJA-20-00060  0.511
2020 Ichino N, Serres MR, Urban RM, Urban MD, Treichel AJ, Schaefbauer KJ, Greif LE, Varshney GK, Skuster KJ, McNulty MS, Daby CL, Wang Y, Liao HK, El-Rass S, Ding Y, ... ... Ekker SC, et al. Building the vertebrate codex using the gene breaking protein trap library. Elife. 9. PMID 32779569 DOI: 10.7554/Elife.54572  0.765
2020 Wierson WA, Welker JM, Almeida MP, Mann CM, Webster DA, Torrie ME, Weiss TJ, Kambakam S, Vollbrecht MK, Lan M, McKeighan KC, Levey J, Ming Z, Wehmeier A, Mikelson CS, ... ... Ekker SC, et al. Efficient targeted integration directed by short homology in zebrafish and mammalian cells. Elife. 9. PMID 32412410 DOI: 10.7554/Elife.53968  0.668
2020 Ma X, Zhu P, Ding Y, Zhang H, Qiu Q, Dvornikov AV, Wang Z, Kim M, Wang Y, Lowerison M, Yu Y, Norton N, Herrmann J, Ekker SC, Hsiai TK, et al. Retinoid X receptor alpha is a spatiotemporally predominant therapeutic target for anthracycline-induced cardiotoxicity. Science Advances. 6: eaay2939. PMID 32064346 DOI: 10.1126/Sciadv.Aay2939  0.359
2020 Ichino N, Serres MR, Urban RM, Urban MD, Treichel AJ, Schaefbauer KJ, Greif LE, Varshney GK, Skuster KJ, McNulty MS, Daby CL, Wang Y, Liao H, El-Rass S, Ding Y, ... ... Ekker SC, et al. Author response: Building the vertebrate codex using the gene breaking protein trap library Elife. DOI: 10.7554/Elife.54572.Sa2  0.725
2020 Wierson WA, Welker JM, Almeida MP, Mann CM, Webster DA, Torrie ME, Weiss TJ, Kambakam S, Vollbrecht MK, Lan M, McKeighan KC, Levey J, Ming Z, Wehmeier A, Mikelson CS, ... ... Ekker SC, et al. Author response: Efficient targeted integration directed by short homology in zebrafish and mammalian cells Elife. DOI: 10.7554/Elife.53968.Sa2  0.615
2020 Mehra D, Banerjee C, Adhikari S, Clark KJ, Ekker SC, Puchner EM. Characterization of dCas9 Interaction Kinetics and Local Chromatin Structure in Live Human Cells using Palm Superresolution Microscopy Biophysical Journal. 118: 146a. DOI: 10.1016/J.Bpj.2019.11.919  0.582
2019 Wierson WA, Simone BW, WareJoncas Z, Mann C, Welker JM, Kar B, Emch MJ, Friedberg I, Gendron WAC, Barry MA, Clark KJ, Dobbs DL, McGrail MA, Ekker SC, Essner JJ. Expanding the CRISPR Toolbox with ErCas12a in Zebrafish and Human Cells. The Crispr Journal. PMID 31742435 DOI: 10.1089/crispr.2019.0026  0.617
2019 Mann CM, Martínez-Gálvez G, Welker JM, Wierson WA, Ata H, Almeida MP, Clark KJ, Essner JJ, McGrail M, Ekker SC, Dobbs D. The Gene Sculpt Suite: a set of tools for genome editing. Nucleic Acids Research. PMID 31127311 DOI: 10.1093/Nar/Gkz405  0.645
2018 Greenberg-Worisek AJ, Campbell KA, Klee EW, Staff NP, Schimmenti LA, Weavers KM, Ekker SC, Windebank AJ. Case-Based Learning in Translational Biomedical Research Education Provides More Realistic and Adaptive Skills for Early-Career Scientists Than Didactic Sessions. Academic Medicine : Journal of the Association of American Medical Colleges. PMID 30256254 DOI: 10.1097/Acm.0000000000002470  0.54
2018 Reiman JM, Das B, Sindberg GM, Urban MD, Hammerlund MEM, Lee HB, Spring KM, Lyman-Gingerich J, Generous AR, Koep TH, Ewing K, Lilja P, Enders FT, Ekker SC, Huskins WC, et al. Humidity as a non-pharmaceutical intervention for influenza A. Plos One. 13: e0204337. PMID 30252890 DOI: 10.1371/Journal.Pone.0204337  0.544
2018 Ata H, Ekstrom TL, Martínez-Gálvez G, Mann CM, Dvornikov AV, Schaefbauer KJ, Ma AC, Dobbs D, Clark KJ, Ekker SC. Robust Activation of Microhomology-mediated End Joining for Precision Gene Editing Applications. Plos Genetics. 14: e1007652. PMID 30208061 DOI: 10.1371/Journal.Pgen.1007652  0.686
2018 Ignatius MS, Hayes MN, Moore FE, Tang Q, Garcia SP, Blackburn PR, Baxi K, Wang L, Jin A, Ramakrishnan A, Reeder S, Chen Y, Nielsen GP, Chen EY, Hasserjian RP, ... ... Ekker SC, et al. deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish. Elife. 7. PMID 30192230 DOI: 10.7554/Elife.37202  0.559
2018 WareJoncas Z, Campbell JM, Martínez-Gálvez G, Gendron WAC, Barry MA, Harris PC, Sussman CR, Ekker SC. Precision gene editing technology and applications in nephrology. Nature Reviews. Nephrology. PMID 30089813 DOI: 10.1038/S41581-018-0047-X  0.38
2018 Simone BW, Martínez-Gálvez G, WareJoncas Z, Ekker SC. Fishing for understanding: Unlocking the zebrafish gene editor's toolbox. Methods (San Diego, Calif.). PMID 30076892 DOI: 10.1016/J.Ymeth.2018.07.012  0.386
2017 Ding Y, Long PA, Bos JM, Shih YH, Ma X, Sundsbak RS, Chen J, Jiang Y, Zhao L, Hu X, Wang J, Shi Y, Ackerman MJ, Lin X, Ekker SC, et al. A modifier screen identifies DNAJB6 as a cardiomyopathy susceptibility gene. Jci Insight. 2. PMID 28422763 DOI: 10.1172/Jci.Insight.94086  0.355
2017 El-Rass S, Eisa-Beygi S, Khong E, Brand-Arzamendi K, Mauro A, Zhang H, Clark KJ, Ekker SC, Wen XY. Disruption of pdgfra alters endocardial and myocardial fusion during zebrafish cardiac assembly. Biology Open. PMID 28167492 DOI: 10.1242/Bio.021212  0.626
2016 Ma AC, Chen Y, Blackburn PR, Ekker SC. TALEN-Mediated Mutagenesis and Genome Editing. Methods in Molecular Biology (Clifton, N.J.). 1451: 17-30. PMID 27464798 DOI: 10.1007/978-1-4939-3771-4_2  0.35
2016 Ata H, Clark KJ, Ekker SC. The zebrafish genome editing toolkit. Methods in Cell Biology. 135: 149-70. PMID 27443924 DOI: 10.1016/Bs.Mcb.2016.04.023  0.651
2016 Blackburn PR, Hickey RD, Nace RA, Giama NH, Kraft DL, Bordner AJ, Chaiteerakij R, McCormick JB, Radulovic M, Graham RP, Torbenson MS, Tortorelli S, Scott CR, Lindor NM, Milliner DS, ... ... Ekker SC, et al. Silent Tyrosinemia Type I Without Elevated Tyrosine or Succinylacetone Associated With Liver Cirrhosis and Hepatocellular Carcinoma. Human Mutation. PMID 27397503 DOI: 10.1002/Humu.23047  0.594
2016 Welker JM, Wierson WA, Wang Y, McNulty MS, Tanya PL, Tisdale EE, Solin SL, Ekker SC, Clark KJ, McGrail MA, Essner JJ. GoldyTALEN Vectors with Improved Efficiency for Golden Gate TALEN Assembly. Human Gene Therapy. PMID 27094430 DOI: 10.1089/Hum.2016.012  0.624
2016 Ni J, Wangensteen KJ, Nelsen D, Balciunas D, Skuster KJ, Urban MD, Ekker SC. Active recombinant Tol2 transposase for gene transfer and gene discovery applications. Mobile Dna. 7: 6. PMID 27042235 DOI: 10.1186/S13100-016-0062-Z  0.699
2016 Leveque RE, Clark KJ, Ekker SC. Mayo Clinic Zebrafish Facility Overview. Zebrafish. PMID 27023741 DOI: 10.1089/Zeb.2015.1227  0.633
2016 Ma AC, McNulty MS, Tanya PL, Jarryd CM, Martínez-Gálvez G, Argue DP, Lee HB, Urban MD, Bullard CE, Blackburn PR, Man TK, Clark KJ, Ekker SC. FusX: A rapid one-step TALE assembly system for genome science. Human Gene Therapy. PMID 26854857 DOI: 10.1089/Hum.2015.172  0.742
2015 Westcot SE, Hatzold J, Urban MD, Richetti SK, Skuster KJ, Harm RM, Lopez Cervera R, Umemoto N, McNulty MS, Clark KJ, Hammerschmidt M, Ekker SC. Protein-Trap Insertional Mutagenesis Uncovers New Genes Involved in Zebrafish Skin Development, Including a Neuregulin 2a-Based ErbB Signaling Pathway Required during Median Fin Fold Morphogenesis. Plos One. 10: e0130688. PMID 26110643 DOI: 10.1371/Journal.Pone.0130688  0.656
2015 Craig MP, Grajevskaja V, Liao HK, Balciuniene J, Ekker SC, Park JS, Essner JJ, Balciunas D, Sumanas S. Etv2 and fli1b function together as key regulators of vasculogenesis and angiogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 865-76. PMID 25722433 DOI: 10.1161/Atvbaha.114.304768  0.661
2015 Bedell VM, Ekker SC. Using engineered endonucleases to create knockout and knockin zebrafish models. Methods in Molecular Biology (Clifton, N.J.). 1239: 291-305. PMID 25408414 DOI: 10.1007/978-1-4939-1862-1_17  0.335
2015 Blackburn P, Hickey R, Nace R, Giama NH, Chaiteerakij R, Bordner A, Kraft D, Oglesbee D, Al-Qabandi W, Grompe M, Clark KJ, Klee EW, Gavrilov D, Roberts LR, El-Youssef M, ... Ekker SC, et al. 549 Tyrosinemia Without Succinylacetone: Modeling a Novel Mutation in FAH in Family With Early Onset Cirrhosis and Hepatocellular Carcinoma Gastroenterology. 148: S-111. DOI: 10.1016/S0016-5085(15)30381-4  0.576
2014 Peng Y, Clark KJ, Campbell JM, Panetta MR, Guo Y, Ekker SC. Making designer mutants in model organisms. Development (Cambridge, England). 141: 4042-54. PMID 25336735 DOI: 10.1242/Dev.102186  0.641
2013 Campbell JM, Hartjes KA, Nelson TJ, Xu X, Ekker SC. New and TALENted genome engineering toolbox. Circulation Research. 113: 571-87. PMID 23948583 DOI: 10.1161/Circresaha.113.301765  0.357
2013 Ma AC, Lee HB, Clark KJ, Ekker SC. High efficiency In Vivo genome engineering with a simplified 15-RVD GoldyTALEN design. Plos One. 8: e65259. PMID 23734242 DOI: 10.1371/Journal.Pone.0065259  0.738
2013 Tietz Bogert PS, Huang BQ, Gradilone SA, Masyuk TV, Moulder GL, Ekker SC, Larusso NF. The zebrafish as a model to study polycystic liver disease. Zebrafish. 10: 211-7. PMID 23668934 DOI: 10.1089/Zeb.2012.0825  0.314
2013 Patowary A, Purkanti R, Singh M, Chauhan R, Singh AR, Swarnkar M, Singh N, Pandey V, Torroja C, Clark MD, Kocher JP, Clark KJ, Stemple DL, Klee EW, Ekker SC, et al. A sequence-based variation map of zebrafish. Zebrafish. 10: 15-20. PMID 23590399 DOI: 10.1089/Zeb.2012.0848  0.646
2013 Blackburn PR, Campbell JM, Clark KJ, Ekker SC. The CRISPR system--keeping zebrafish gene targeting fresh. Zebrafish. 10: 116-8. PMID 23536990 DOI: 10.1089/Zeb.2013.9999  0.651
2013 Chen Z, Lee H, Henle SJ, Cheever TR, Ekker SC, Henley JR. Primary neuron culture for nerve growth and axon guidance studies in zebrafish (Danio rerio). Plos One. 8: e57539. PMID 23469201 DOI: 10.1371/Journal.Pone.0057539  0.726
2013 Neff KL, Argue DP, Ma AC, Lee HB, Clark KJ, Ekker SC. Mojo Hand, a TALEN design tool for genome editing applications. Bmc Bioinformatics. 14: 1. PMID 23323762 DOI: 10.1186/1471-2105-14-1  0.725
2013 Ding Y, Liu W, Deng Y, Jomok B, Yang J, Huang W, Clark KJ, Zhong TP, Lin X, Ekker SC, Xu X. Trapping cardiac recessive mutants via expression-based insertional mutagenesis screening. Circulation Research. 112: 606-17. PMID 23283723 DOI: 10.1161/Circresaha.112.300603  0.64
2013 Khurana S, Buckley S, Schouteden S, Ekker S, Petryk A, Delforge M, Zwijsen A, Verfaillie CM. A novel role of BMP4 in adult hematopoietic stem and progenitor cell homing via Smad independent regulation of integrin-α4 expression. Blood. 121: 781-90. PMID 23243277 DOI: 10.1182/Blood-2012-07-446443  0.311
2012 Sohni A, Mulas F, Ferrazzi F, Luttun A, Bellazzi R, Huylebroeck D, Ekker SC, Verfaillie CM. TGFβ1-induced Baf60c regulates both smooth muscle cell commitment and quiescence. Plos One. 7: e47629. PMID 23110084 DOI: 10.1371/Journal.Pone.0047629  0.356
2012 Hoffman SJ, Psaltis PJ, Clark KJ, Spoon DB, Chue CD, Ekker SC, Simari RD. An in vivo method to quantify lymphangiogenesis in zebrafish. Plos One. 7: e45240. PMID 23028871 DOI: 10.1371/Journal.Pone.0045240  0.63
2012 Bedell VM, Wang Y, Campbell JM, Poshusta TL, Starker CG, Krug RG, Tan W, Penheiter SG, Ma AC, Leung AY, Fahrenkrug SC, Carlson DF, Voytas DF, Clark KJ, Essner JJ, ... Ekker SC, et al. In vivo genome editing using a high-efficiency TALEN system. Nature. 491: 114-8. PMID 23000899 DOI: 10.1038/Nature11537  0.799
2012 Hoeppner LH, Phoenix KN, Clark KJ, Bhattacharya R, Gong X, Sciuto TE, Vohra P, Suresh S, Bhattacharya S, Dvorak AM, Ekker SC, Dvorak HF, Claffey KP, Mukhopadhyay D. Revealing the role of phospholipase Cβ3 in the regulation of VEGF-induced vascular permeability. Blood. 120: 2167-73. PMID 22674805 DOI: 10.1182/Blood-2012-03-417824  0.625
2012 McNulty MS, Bedell VM, Greenwood TM, Craig TA, Ekker SC, Kumar R. Expression of sclerostin in the developing zebrafish (Danio rerio) brain and skeleton. Gene Expression Patterns : Gep. 12: 228-35. PMID 22575304 DOI: 10.1016/J.Gep.2012.04.003  0.353
2012 Xu J, Gao J, Li J, Xue L, Clark KJ, Ekker SC, Du SJ. Functional analysis of slow myosin heavy chain 1 and myomesin-3 in sarcomere organization in zebrafish embryonic slow muscles. Journal of Genetics and Genomics = Yi Chuan Xue Bao. 39: 69-80. PMID 22361506 DOI: 10.1016/J.Jgg.2012.01.005  0.609
2012 Liao HK, Wang Y, Noack Watt KE, Wen Q, Breitbach J, Kemmet CK, Clark KJ, Ekker SC, Essner JJ, McGrail M. Tol2 gene trap integrations in the zebrafish amyloid precursor protein genes appa and aplp2 reveal accumulation of secreted APP at the embryonic veins. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 241: 415-25. PMID 22275008 DOI: 10.1002/Dvdy.23725  0.631
2012 Bedell VM, Person AD, Larson JD, McLoon A, Balciunas D, Clark KJ, Neff KI, Nelson KE, Bill BR, Schimmenti LA, Beiraghi S, Ekker SC. The lineage-specific gene ponzr1 is essential for zebrafish pronephric and pharyngeal arch development. Development (Cambridge, England). 139: 793-804. PMID 22274699 DOI: 10.1242/Dev.071720  0.802
2012 Klee EW, Schneider H, Clark KJ, Cousin MA, Ebbert JO, Hooten WM, Karpyak VM, Warner DO, Ekker SC. Zebrafish: a model for the study of addiction genetics. Human Genetics. 131: 977-1008. PMID 22207143 DOI: 10.1007/S00439-011-1128-0  0.594
2012 Clark KJ, Argue DP, Petzold AM, Ekker SC. zfishbook: connecting you to a world of zebrafish revertible mutants. Nucleic Acids Research. 40: D907-11. PMID 22067444 DOI: 10.1093/Nar/Gkr957  0.795
2011 Ma AC, Fung TK, Lin RH, Chung MI, Yang D, Ekker SC, Leung AY. Methionine aminopeptidase 2 is required for HSC initiation and proliferation. Blood. 118: 5448-57. PMID 21937698 DOI: 10.1182/Blood-2011-04-350173  0.346
2011 Clark KJ, Voytas DF, Ekker SC. A TALE of two nucleases: gene targeting for the masses? Zebrafish. 8: 147-9. PMID 21929364 DOI: 10.1089/Zeb.2011.9993  0.662
2011 Clark KJ, Urban MD, Skuster KJ, Ekker SC. Transgenic zebrafish using transposable elements. Methods in Cell Biology. 104: 137-49. PMID 21924161 DOI: 10.1016/B978-0-12-374814-0.00008-2  0.614
2011 Ding Y, Sun X, Huang W, Hoage T, Redfield M, Kushwaha S, Sivasubbu S, Lin X, Ekker S, Xu X. Haploinsufficiency of target of rapamycin attenuates cardiomyopathies in adult zebrafish Circulation Research. 109: 658-669. PMID 21757652 DOI: 10.1161/Circresaha.111.248260  0.305
2011 Bedell VM, Westcot SE, Ekker SC. Lessons from morpholino-based screening in zebrafish. Briefings in Functional Genomics. 10: 181-8. PMID 21746693 DOI: 10.1093/Bfgp/Elr021  0.346
2011 Clark KJ, Boczek NJ, Ekker SC. Stressing zebrafish for behavioral genetics. Reviews in the Neurosciences. 22: 49-62. PMID 21615261 DOI: 10.1515/Rns.2011.007  0.601
2011 Clark KJ, Balciunas D, Pogoda HM, Ding Y, Westcot SE, Bedell VM, Greenwood TM, Urban MD, Skuster KJ, Petzold AM, Ni J, Nielsen AL, Patowary A, Scaria V, Sivasubbu S, ... ... Ekker SC, et al. In vivo protein trapping produces a functional expression codex of the vertebrate proteome. Nature Methods. 8: 506-15. PMID 21552255 DOI: 10.1038/Nmeth.1606  0.808
2011 Alexandre D, Alonzeau J, Bill BR, Ekker SC, Waschek JA. Expression analysis of PAC1-R and PACAP genes in zebrafish embryos. Journal of Molecular Neuroscience : Mn. 43: 94-100. PMID 20526695 DOI: 10.1007/S12031-010-9397-Y  0.747
2011 Westcot SE, Clark KJ, Skuster K, Urban M, Moulder G, Greenwood TM, Balciunas D, Sivasubbu S, Ekker SC. How to skin a fish: The Zebrafish Integument Project and novel epidermal mutant wicked witch of the Midwest Developmental Biology. 356: 158. DOI: 10.1016/J.Ydbio.2011.05.586  0.61
2011 Bedell VM, Person A, Larson J, McLoon A, Balciunas D, Clark K, Nelson K, Bill B, Schimmenti L, Beiraghi S, Ekker S. Vertebrate kidney innovation by ponzr1 Developmental Biology. 356: 255. DOI: 10.1016/J.Ydbio.2011.05.579  0.747
2010 Wang Y, Kaiser MS, Larson JD, Nasevicius A, Clark KJ, Wadman SA, Roberg-Perez SE, Ekker SC, Hackett PB, McGrail M, Essner JJ. Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis. Development (Cambridge, England). 137: 3119-28. PMID 20736288 DOI: 10.1242/Dev.048785  0.782
2010 He Z, Zhang H, Zhang X, Xie D, Chen Y, Wangensteen KJ, Ekker SC, Firpo M, Liu C, Xiang D, Zi X, Hui L, Yang G, Ding X, Hu Y, et al. Liver xeno-repopulation with human hepatocytes in Fah-/-Rag2-/- mice after pharmacological immunosuppression. The American Journal of Pathology. 177: 1311-9. PMID 20651238 DOI: 10.2353/Ajpath.2010.091154  0.634
2010 Huang X, Guo H, Tammana S, Jung YC, Mellgren E, Bassi P, Cao Q, Tu ZJ, Kim YC, Ekker SC, Wu X, Wang SM, Zhou X. Gene transfer efficiency and genome-wide integration profiling of Sleeping Beauty, Tol2, and piggyBac transposons in human primary T cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1803-13. PMID 20606646 DOI: 10.1038/Mt.2010.141  0.324
2010 Petzold AM, Bedell VM, Boczek NJ, Essner JJ, Balciunas D, Clark KJ, Ekker SC. SCORE imaging: specimen in a corrected optical rotational enclosure. Zebrafish. 7: 149-54. PMID 20528262 DOI: 10.1089/Zeb.2010.0660  0.766
2010 Person AD, Beiraghi S, Sieben CM, Hermanson S, Neumann AN, Robu ME, Schleiffarth JR, Billington CJ, van Bokhoven H, Hoogeboom JM, Mazzeu JF, Petryk A, Schimmenti LA, Brunner HG, Ekker SC, et al. WNT5A mutations in patients with autosomal dominant Robinow syndrome. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 327-37. PMID 19918918 DOI: 10.1002/Dvdy.22156  0.579
2009 Petzold AM, Balciunas D, Sivasubbu S, Clark KJ, Bedell VM, Westcot SE, Myers SR, Moulder GL, Thomas MJ, Ekker SC. Nicotine response genetics in the zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 106: 18662-7. PMID 19858493 DOI: 10.1073/Pnas.0908247106  0.783
2009 Keng VW, Ryan BJ, Wangensteen KJ, Balciunas D, Schmedt C, Ekker SC, Largaespada DA. Efficient transposition of Tol2 in the mouse germline. Genetics. 183: 1565-73. PMID 19805821 DOI: 10.1534/Genetics.109.100768  0.691
2009 Petzold AM, Clark KJ, Ekker SC. Spotlight on the future of scientific publication. Zebrafish. 6: 215-7. PMID 19761376 DOI: 10.1089/Zeb.2009.9992  0.742
2009 Bill BR, Petzold AM, Clark KJ, Schimmenti LA, Ekker SC. A primer for morpholino use in zebrafish. Zebrafish. 6: 69-77. PMID 19374550 DOI: 10.1089/Zeb.2008.0555  0.768
2008 Ekker SC, Parichy DM, Cheng KC. Research implications of pigment biology in zebrafish. Zebrafish. 5: 233-5. PMID 19133820 DOI: 10.1089/Zeb.2008.9981  0.328
2008 Ni J, Clark KJ, Fahrenkrug SC, Ekker SC. Transposon tools hopping in vertebrates. Briefings in Functional Genomics & Proteomics. 7: 444-53. PMID 19109308 DOI: 10.1093/Bfgp/Eln049  0.762
2008 Bill BR, Balciunas D, McCarra JA, Young ED, Xiong T, Spahn AM, Garcia-Lecea M, Korzh V, Ekker SC, Schimmenti LA. Development and Notch signaling requirements of the zebrafish choroid plexus. Plos One. 3: e3114. PMID 18769591 DOI: 10.1371/Journal.Pone.0003114  0.788
2008 Ekker SC. Zinc finger-based knockout punches for zebrafish genes. Zebrafish. 5: 121-3. PMID 18554175 DOI: 10.1089/Zeb.2008.9988  0.384
2008 Chen J, Ekker SC. Modulation of gene expression in the study of zebrafish development - A discussion with James Chen, Ph.D Zebrafish. 5: 93-96. PMID 18554172 DOI: 10.1089/Zeb.2008.9993  0.303
2008 Wangensteen KJ, Wilber A, Keng VW, He Z, Matise I, Wangensteen L, Carson CM, Chen Y, Steer CJ, McIvor RS, Largaespada DA, Wang X, Ekker SC. A facile method for somatic, lifelong manipulation of multiple genes in the mouse liver. Hepatology (Baltimore, Md.). 47: 1714-24. PMID 18435462 DOI: 10.1002/Hep.22195  0.698
2008 Knowlton MN, Li T, Ren Y, Bill BR, Ellis LB, Ekker SC. A PATO-compliant zebrafish screening database (MODB): management of morpholino knockdown screen information. Bmc Bioinformatics. 9: 7. PMID 18179718 DOI: 10.1186/1471-2105-9-7  0.759
2008 Wangensteen KJ, Wilber A, Keng VW, Chen Y, Matise I, Wangensteen L, Steer CJ, McIvor RS, Largaespada DA, Wang X, Ekker SC. A method for lifelong genetic manipulation of regenerating hepatocytes in mouse Cell Research. 18: S31-S31. DOI: 10.1038/Cr.2008.121  0.667
2007 Ekker SC, Stemple DL, Clark M, Chien CB, Rasooly RS, Javois LC. Zebrafish genome project: bringing new biology to the vertebrate genome field. Zebrafish. 4: 239-51. PMID 18284331 DOI: 10.1089/Zeb.2007.9979  0.326
2007 Sivasubbu S, Balciunas D, Amsterdam A, Ekker SC. Insertional mutagenesis strategies in zebrafish. Genome Biology. 8: S9. PMID 18047701 DOI: 10.1186/Gb-2007-8-S1-S9  0.352
2007 Alvarez Y, Cederlund ML, Cottell DC, Bill BR, Ekker SC, Torres-Vazquez J, Weinstein BM, Hyde DR, Vihtelic TS, Kennedy BN. Genetic determinants of hyaloid and retinal vasculature in zebrafish. Bmc Developmental Biology. 7: 114. PMID 17937808 DOI: 10.1186/1471-213X-7-114  0.738
2007 Robu ME, Larson JD, Nasevicius A, Beiraghi S, Brenner C, Farber SA, Ekker SC. p53 activation by knockdown technologies. Plos Genetics. 3: e78. PMID 17530925 DOI: 10.1371/Journal.Pgen.0030078  0.786
2007 Schleiffarth JR, Person AD, Martinsen BJ, Sukovich DJ, Neumann A, Baker CV, Lohr JL, Cornfield DN, Ekker SC, Petryk A. Wnt5a is required for cardiac outflow tract septation in mice. Pediatric Research. 61: 386-91. PMID 17515859 DOI: 10.1203/Pdr.0B013E3180323810  0.312
2007 Wilber A, Wangensteen KJ, Chen Y, Zhuo L, Frandsen JL, Bell JB, Chen ZJ, Ekker SC, McIvor RS, Wang X. Messenger RNA as a source of transposase for sleeping beauty transposon-mediated correction of hereditary tyrosinemia type I. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1280-7. PMID 17440442 DOI: 10.1038/Sj.Mt.6300160  0.688
2007 Patterson LJ, Gering M, Eckfeldt CE, Green AR, Verfaillie CM, Ekker SC, Patient R. The transcription factors Scl and Lmo2 act together during development of the hemangioblast in zebrafish. Blood. 109: 2389-98. PMID 17090656 DOI: 10.1182/Blood-2006-02-003087  0.398
2006 Pickart MA, Klee EW, Nielsen AL, Sivasubbu S, Mendenhall EM, Bill BR, Chen E, Eckfeldt CE, Knowlton M, Robu ME, Larson JD, Deng Y, Schimmenti LA, Ellis LB, Verfaillie CM, ... ... Ekker SC, et al. Genome-wide reverse genetics framework to identify novel functions of the vertebrate secretome. Plos One. 1: e104. PMID 17218990 DOI: 10.1371/Journal.Pone.0000104  0.811
2006 Balciunas D, Wangensteen KJ, Wilber A, Bell J, Geurts A, Sivasubbu S, Wang X, Hackett PB, Largaespada DA, McIvor RS, Ekker SC. Harnessing a high cargo-capacity transposon for genetic applications in vertebrates. Plos Genetics. 2: e169. PMID 17096595 DOI: 10.1371/Journal.Pgen.0020169  0.775
2006 Sivasubbu S, Balciunas D, Davidson AE, Pickart MA, Hermanson SB, Wangensteen KJ, Wolbrink DC, Ekker SC. Gene-breaking transposon mutagenesis reveals an essential role for histone H2afza in zebrafish larval development. Mechanisms of Development. 123: 513-29. PMID 16859902 DOI: 10.1016/J.Mod.2006.06.002  0.799
2006 Chen E, Larson JD, Ekker SC. Functional analysis of zebrafish microfibril-associated glycoprotein-1 (Magp1) in vivo reveals roles for microfibrils in vascular development and function. Blood. 107: 4364-74. PMID 16469878 DOI: 10.1182/Blood-2005-02-0789  0.608
2006 Essner JJ, Chen E, Ekker SC. Syndecan-2. The International Journal of Biochemistry & Cell Biology. 38: 152-6. PMID 16198615 DOI: 10.1016/j.biocel.2005.08.012  0.529
2006 Wilber A, Wangensteen KJ, Chen Y, Zhou L, Frandsen JL, Bell J, Chen Z, Ekker SC, McIvor RS, Wang X. 405. Correction of the Murine Model of Hereditary Tyrosinemia Type I Using Messenger RNA as a Source of Transposase for Sleeping Beauty Mediated Integration of the FAH Gene Molecular Therapy. 13: S155-S156. DOI: 10.1016/J.Ymthe.2006.08.468  0.701
2006 Balciunas D, Wilber A, Wangensteen K, Bell J, Geurts A, Hackett PB, Largaespada DA, McIvor RS, Ekker SC. 385. Tol2 Transposon as a Gene Therapy Vector: Characterization, Optimization and Correction of Hereditary Tyrosinemia Type 1 in Mouse Molecular Therapy. 13: S147. DOI: 10.1016/J.Ymthe.2006.08.446  0.759
2006 Bill BR, DeLuca A, Warman B, Larson JD, Ekker SC, Schimmenti LA. Knockdown of alpha-1-microglobulin bikunin precursor (AMBP) causes ocular, and craniofacial defects Developmental Biology. 295: 463. DOI: 10.1016/J.Ydbio.2006.04.425  0.749
2005 Wilber A, Frandsen JL, Wangensteen KJ, Ekker SC, Wang X, McIvor RS. Dynamic gene expression after systemic delivery of plasmid DNA as determined by in vivo bioluminescence imaging. Human Gene Therapy. 16: 1325-32. PMID 16259566 DOI: 10.1089/Hum.2005.16.1325  0.707
2005 Kim HJ, Schleiffarth JR, Jessurun J, Sumanas S, Petryk A, Lin S, Ekker SC. Wnt5 signaling in vertebrate pancreas development. Bmc Biology. 3: 23. PMID 16246260 DOI: 10.1186/1741-7007-3-23  0.734
2005 Ohlfest JR, Demorest ZL, Motooka Y, Vengco I, Oh S, Chen E, Scappaticci FA, Saplis RJ, Ekker SC, Low WC, Freese AB, Largaespada DA. Combinatorial antiangiogenic gene therapy by nonviral gene transfer using the sleeping beauty transposon causes tumor regression and improves survival in mice bearing intracranial human glioblastoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 778-88. PMID 16150649 DOI: 10.1016/J.Ymthe.2005.07.689  0.567
2005 Hackett PB, Ekker SC, Largaespada DA, McIvor RS. Sleeping beauty transposon-mediated gene therapy for prolonged expression. Advances in Genetics. 54: 189-232. PMID 16096013 DOI: 10.1016/S0065-2660(05)54009-4  0.604
2005 Eckfeldt CE, Mendenhall EM, Flynn CM, Wang TF, Pickart MA, Grindle SM, Ekker SC, Verfaillie CM. Functional analysis of human hematopoietic stem cell gene expression using zebrafish. Plos Biology. 3: e254. PMID 16089502 DOI: 10.1371/Journal.Pbio.0030254  0.373
2005 Chen E, Stringer SE, Rusch MA, Selleck SB, Ekker SC. A unique role for 6-O sulfation modification in zebrafish vascular development. Developmental Biology. 284: 364-76. PMID 16009360 DOI: 10.1016/J.Ydbio.2005.05.032  0.617
2005 Klee EW, Shim KJ, Pickart MA, Ekker SC, Ellis LB. AMOD: a morpholino oligonucleotide selection tool. Nucleic Acids Research. 33: W506-11. PMID 15980523 DOI: 10.1093/Nar/Gki453  0.307
2005 Leung AY, Mendenhall EM, Kwan TT, Liang R, Eckfeldt C, Chen E, Hammerschmidt M, Grindley S, Ekker SC, Verfaillie CM. Characterization of expanded intermediate cell mass in zebrafish chordin morphant embryos. Developmental Biology. 277: 235-54. PMID 15572152 DOI: 10.1016/J.Ydbio.2004.09.032  0.611
2005 Wangensteen KJ, Wilber A, Zeng G, Frandsen JL, McIvor RS, Ekker SC, Wang X. 1068. Luciferase as an In Vivo Reporter for Selective Liver Repopulation in Adult FAH-/- Mice Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.615  0.687
2004 Hermanson S, Davidson AE, Sivasubbu S, Balciunas D, Ekker SC. Sleeping Beauty transposon for efficient gene delivery. Methods in Cell Biology. 77: 349-62. PMID 15602921 DOI: 10.1016/S0091-679X(04)77019-3  0.681
2004 Ekker SC. Nonconventional antisense in zebrafish for functional genomics applications. Methods in Cell Biology. 77: 121-36. PMID 15602909 DOI: 10.1016/S0091-679X(04)77007-7  0.421
2004 Chen E, Ekker SC. Zebrafish as a genomics research model. Current Pharmaceutical Biotechnology. 5: 409-13. PMID 15544488 DOI: 10.2174/1389201043376652  0.63
2004 Pickart MA, Sivasubbu S, Nielsen AL, Shriram S, King RA, Ekker SC. Functional genomics tools for the analysis of zebrafish pigment. Pigment Cell Research / Sponsored by the European Society For Pigment Cell Research and the International Pigment Cell Society. 17: 461-70. PMID 15357832 DOI: 10.1111/J.1600-0749.2004.00189.X  0.44
2004 Balciunas D, Davidson AE, Sivasubbu S, Hermanson SB, Welle Z, Ekker SC. Enhancer trapping in zebrafish using the Sleeping Beauty transposon. Bmc Genomics. 5: 62. PMID 15347431 DOI: 10.1186/1471-2164-5-62  0.684
2004 Larson JD, Wadman SA, Chen E, Kerley L, Clark KJ, Eide M, Lippert S, Nasevicius A, Ekker SC, Hackett PB, Essner JJ. Expression of VE-cadherin in zebrafish embryos: a new tool to evaluate vascular development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 231: 204-13. PMID 15305301 DOI: 10.1002/Dvdy.20102  0.787
2004 Klee EW, Carlson DF, Fahrenkrug SC, Ekker SC, Ellis LB. Identifying secretomes in people, pufferfish and pigs. Nucleic Acids Research. 32: 1414-21. PMID 14990746 DOI: 10.1093/Nar/Gkh286  0.635
2004 Chen E, Hermanson S, Ekker SC. Syndecan-2 is essential for angiogenic sprouting during zebrafish development. Blood. 103: 1710-9. PMID 14592839 DOI: 10.1182/Blood-2003-06-1783  0.606
2004 Mendenhall EM, Eckfeldt CE, Ekker SC, Verfaillie CM. The Role of Sprouty Family Members in Hematopiesis in Zebrafish and Mammals. Blood. 104: 137-137. DOI: 10.1182/Blood.V104.11.137.137  0.431
2004 Eckfeldt CE, Mendenhall EM, Ekker SC, Verfaillie CM. Functional Analysis of the Differential Gene Expression Profile of Human HSC Using a Functional Genomics Screen in the Zebrafish. Blood. 104: 136-136. DOI: 10.1182/Blood.V104.11.136.136  0.43
2004 Wangensteen KJ, Chen ZJ, Steer CJ, Ekker SC. 154. Small inhibitory RNA expressed from sleeping beauty transposons can reduce alpha1-antitrypsin expression Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.077  0.696
2003 Davidson AE, Balciunas D, Mohn D, Shaffer J, Hermanson S, Sivasubbu S, Cliff MP, Hackett PB, Ekker SC. Efficient gene delivery and gene expression in zebrafish using the Sleeping Beauty transposon. Developmental Biology. 263: 191-202. PMID 14597195 DOI: 10.1016/J.Ydbio.2003.07.013  0.762
2002 Sumanas S, Kim HJ, Hermanson SB, Ekker SC. Lateral line, nervous system, and maternal expression of Frizzled 7a during zebrafish embryogenesis. Mechanisms of Development. 115: 107-11. PMID 12049772 DOI: 10.1016/S0925-4773(02)00084-9  0.74
2002 Dupuy AJ, Clark K, Carlson CM, Fritz S, Davidson AE, Markley KM, Finley K, Fletcher CF, Ekker SC, Hackett PB, Horn S, Largaespada DA. Mammalian germ-line transgenesis by transposition. Proceedings of the National Academy of Sciences of the United States of America. 99: 4495-9. PMID 11904379 DOI: 10.1073/Pnas.062630599  0.794
2001 Nasevicius A, Ekker SC. The zebrafish as a novel system for functional genomics and therapeutic development applications. Current Opinion in Molecular Therapeutics. 3: 224-8. PMID 11497344  0.802
2001 Bingham S, Nasevicius A, Ekker SC, Chandrasekhar A. Sonic hedgehog and tiggy-winkle hedgehog cooperatively induce zebrafish branchiomotor neurons. Genesis (New York, N.Y. : 2000). 30: 170-4. PMID 11477700 DOI: 10.1002/Gene.1057  0.787
2001 Klee EW, Ekker SC, Ellis LB. Target selection for Danio rerio functional genomics. Genesis (New York, N.Y. : 2000). 30: 123-5. PMID 11477688 DOI: 10.1002/Gene.1045  0.324
2001 Sumanas S, Ekker SC. Xenopus frizzled-7 morphant displays defects in dorsoventral patterning and convergent extension movements during gastrulation. Genesis (New York, N.Y. : 2000). 30: 119-22. PMID 11477687 DOI: 10.1002/Gene.1044  0.667
2001 Sumanas S, Kim HJ, Hermanson S, Ekker SC. Zebrafish frizzled-2 morphant displays defects in body axis elongation. Genesis (New York, N.Y. : 2000). 30: 114-8. PMID 11477686 DOI: 10.1002/Gene.1043  0.746
2001 Ekker SC, Larson JD. Morphant technology in model developmental systems. Genesis (New York, N.Y. : 2000). 30: 89-93. PMID 11477681 DOI: 10.1002/Gene.1038  0.414
2001 Finley KR, Davidson AE, Ekker SC. Three-color imaging using fluorescent proteins in living zebrafish embryos. Biotechniques. 31: 66-70, 72. PMID 11464522 DOI: 10.2144/01311St02  0.629
2001 Sumanas S, Ekker SC. Xenopus frizzled-5: a frizzled family member expressed exclusively in the neural retina of the developing eye. Mechanisms of Development. 103: 133-6. PMID 11335120 DOI: 10.1016/S0925-4773(01)00327-6  0.671
2001 Ross JJ, Shimmi O, Vilmos P, Petryk A, Kim H, Gaudenz K, Hermanson S, Ekker SC, O'Connor MB, Marsh JL. Twisted gastrulation is a conserved extracellular BMP antagonist. Nature. 410: 479-83. PMID 11260716 DOI: 10.1038/35068578  0.554
2000 Ekker SC. Morphants: a new systematic vertebrate functional genomics approach. Yeast (Chichester, England). 17: 302-306. PMID 11119307 DOI: 10.1002/1097-0061(200012)17:4<302::Aid-Yea53>3.0.Co;2-#  0.4
2000 Nasevicius A, Larson J, Ekker SC. Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant. Yeast (Chichester, England). 17: 294-301. PMID 11119306 DOI: 10.1002/1097-0061(200012)17:4<294::Aid-Yea54>3.0.Co;2-5  0.786
2000 Nasevicius A, Ekker SC. Effective targeted gene 'knockdown' in zebrafish. Nature Genetics. 26: 216-20. PMID 11017081 DOI: 10.1038/79951  0.828
2000 Sumanas S, Strege P, Heasman J, Ekker SC. The putative wnt receptor Xenopus frizzled-7 functions upstream of beta-catenin in vertebrate dorsoventral mesoderm patterning. Development (Cambridge, England). 127: 1981-90. PMID 10751186  0.668
2000 Nasevicius A, Hyatt TM, Hermanson SB, Ekker SC. Sequence, expression, and location of zebrafish frizzled 10. Mechanisms of Development. 92: 311-4. PMID 10727872 DOI: 10.1016/S0925-4773(00)00244-6  0.804
1999 Hyatt TM, Ekker SC. Vectors and techniques for ectopic gene expression in zebrafish. Methods in Cell Biology. 59: 117-26. PMID 9891358 DOI: 10.1016/S0091-679X(08)61823-3  0.404
1998 Nasevicius A, Hyatt T, Kim H, Guttman J, Walsh E, Sumanas S, Wang Y, Ekker SC. Evidence for a frizzled-mediated wnt pathway required for zebrafish dorsal mesoderm formation. Development (Cambridge, England). 125: 4283-92. PMID 9753682  0.785
1995 Ekker SC, Ungar AR, Greenstein P, von Kessler DP, Porter JA, Moon RT, Beachy PA. Patterning activities of vertebrate hedgehog proteins in the developing eye and brain. Current Biology : Cb. 5: 944-55. PMID 7583153 DOI: 10.1016/S0960-9822(95)00185-0  0.366
1994 Lee JJ, Ekker SC, von Kessler DP, Porter JA, Sun BI, Beachy PA. Autoproteolysis in hedgehog protein biogenesis. Science (New York, N.Y.). 266: 1528-37. PMID 7985023 DOI: 10.1126/Science.7985023  0.319
1992 Ekker SC, von Kessler DP, Beachy PA. Differential DNA sequence recognition is a determinant of specificity in homeotic gene action. The Embo Journal. 11: 4059-72. PMID 1356765 DOI: 10.1002/J.1460-2075.1992.Tb05499.X  0.367
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