Stephen C. Ekker, Ph.D. - Publications

Affiliations: 
Mayo Clinic, Rochester, MN, United States 

150 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Mann CM, Martínez-Gálvez G, Welker JM, Wierson WA, Ata H, Almeida MP, Clark KJ, Essner JJ, McGrail M, Ekker SC, Dobbs D. The Gene Sculpt Suite: a set of tools for genome editing. Nucleic Acids Research. PMID 31127311 DOI: 10.1093/nar/gkz405  1
2018 Greenberg-Worisek AJ, Campbell KA, Klee EW, Staff NP, Schimmenti LA, Weavers KM, Ekker SC, Windebank AJ. Case-Based Learning in Translational Biomedical Research Education Provides More Realistic and Adaptive Skills for Early-Career Scientists Than Didactic Sessions. Academic Medicine : Journal of the Association of American Medical Colleges. PMID 30256254 DOI: 10.1097/ACM.0000000000002470  0.96
2018 Reiman JM, Das B, Sindberg GM, Urban MD, Hammerlund MEM, Lee HB, Spring KM, Lyman-Gingerich J, Generous AR, Koep TH, Ewing K, Lilja P, Enders FT, Ekker SC, Huskins WC, et al. Humidity as a non-pharmaceutical intervention for influenza A. Plos One. 13: e0204337. PMID 30252890 DOI: 10.1371/journal.pone.0204337  0.68
2018 Ata H, Ekstrom TL, Martínez-Gálvez G, Mann CM, Dvornikov AV, Schaefbauer KJ, Ma AC, Dobbs D, Clark KJ, Ekker SC. Robust Activation of Microhomology-mediated End Joining for Precision Gene Editing Applications. Plos Genetics. 14: e1007652. PMID 30208061 DOI: 10.1371/journal.pgen.1007652  1
2018 WareJoncas Z, Campbell JM, Martínez-Gálvez G, Gendron WAC, Barry MA, Harris PC, Sussman CR, Ekker SC. Precision gene editing technology and applications in nephrology. Nature Reviews. Nephrology. PMID 30089813 DOI: 10.1038/s41581-018-0047-x  0.48
2018 Simone BW, Martínez-Gálvez G, WareJoncas Z, Ekker SC. Fishing for understanding: Unlocking the zebrafish gene editor's toolbox. Methods (San Diego, Calif.). PMID 30076892 DOI: 10.1016/j.ymeth.2018.07.012  0.48
2018 Hoeppner LH, Sinha S, Wang Y, Bhattacharya R, Dutta S, Gong X, Bedell VM, Suresh S, Chun C, Ramchandran R, Ekker SC, Mukhopadhyay D. Correction: RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells (doi:10.1242/jcs.167601). Journal of Cell Science. 131. PMID 29549170 DOI: 10.1242/jcs.217604  0.52
2017 El-Rass S, Eisa-Beygi S, Khong E, Brand-Arzamendi K, Mauro A, Zhang H, Clark KJ, Ekker SC, Wen XY. Disruption of pdgfra alters endocardial and myocardial fusion during zebrafish cardiac assembly. Biology Open. PMID 28167492 DOI: 10.1242/bio.021212  1
2016 Lee SH, Turchiano G, Ata H, Nowsheen S, Romito M, Lou Z, Ryu SM, Ekker SC, Cathomen T, Kim JS. Failure to detect DNA-guided genome editing using Natronobacterium gregoryi Argonaute. Nature Biotechnology. PMID 27893702 DOI: 10.1038/nbt.3753  0.48
2016 Ma AC, Chen Y, Blackburn PR, Ekker SC. TALEN-Mediated Mutagenesis and Genome Editing. Methods in Molecular Biology (Clifton, N.J.). 1451: 17-30. PMID 27464798 DOI: 10.1007/978-1-4939-3771-4_2  0.68
2016 Blackburn PR, Hickey RD, Nace RA, Giama NH, Kraft DL, Bordner AJ, Chaiteerakij R, McCormick JB, Radulovic M, Graham RP, Torbenson MS, Tortorelli S, Scott CR, Lindor NM, Milliner DS, ... ... Ekker SC, et al. Silent Tyrosinemia Type I Without Elevated Tyrosine or Succinylacetone Associated With Liver Cirrhosis and Hepatocellular Carcinoma. Human Mutation. PMID 27397503 DOI: 10.1002/humu.23047  1
2016 Geurts AM, Ekker SC. Gene Editing: Practical Application in the Lab. Human Gene Therapy. 27: 417-8. PMID 27322167 DOI: 10.1089/hum.2016.29029.amg  1
2016 Martínez-Gálvez G, Ata H, Jarryd CM, Ekker SC. ssDNA and the Argonautes: the quest for the next Golden Editor. Human Gene Therapy. PMID 27230540 DOI: 10.1089/hum.2016.071  0.48
2016 Welker JM, Wierson WA, Wang Y, McNulty MS, Tanya PL, Tisdale EE, Solin SL, Ekker SC, Clark KJ, McGrail MA, Essner JJ. GoldyTALEN Vectors with Improved Efficiency for Golden Gate TALEN Assembly. Human Gene Therapy. PMID 27094430 DOI: 10.1089/hum.2016.012  1
2016 Zhao Y, Wang L, Ren S, Wang L, Blackburn PR, McNulty MS, Gao X, Qiao M, Vessella RL, Kohli M, Zhang J, Karnes RJ, Tindall DJ, Kim Y, MacLeod R, ... Ekker SC, et al. Activation of P-TEFb by Androgen Receptor-Regulated Enhancer RNAs in Castration-Resistant Prostate Cancer. Cell Reports. PMID 27068475 DOI: 10.1016/j.celrep.2016.03.038  1
2016 Ni J, Wangensteen KJ, Nelsen D, Balciunas D, Skuster KJ, Urban MD, Ekker SC. Active recombinant Tol2 transposase for gene transfer and gene discovery applications. Mobile Dna. 7: 6. PMID 27042235 DOI: 10.1186/s13100-016-0062-z  0.72
2016 Leveque RE, Clark KJ, Ekker SC. Mayo Clinic Zebrafish Facility Overview. Zebrafish. PMID 27023741 DOI: 10.1089/zeb.2015.1227  1
2016 Ma AC, McNulty MS, Tanya PL, Jarryd CM, Martínez-Gálvez G, Argue DP, Lee HB, Urban MD, Bullard CE, Blackburn PR, Man TK, Clark KJ, Ekker SC. FusX: A rapid one-step TALE assembly system for genome science. Human Gene Therapy. PMID 26854857 DOI: 10.1089/hum.2015.172  1
2015 Hoeppner LH, Sinha S, Wang Y, Bhattacharya R, Dutta S, Gong X, Bedell VM, Suresh S, Chun CZ, Ramchandran R, Ekker SC, Mukhopadhyay D. RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells. Journal of Cell Science. PMID 26136364 DOI: 10.1242/jcs.167601  0.52
2015 Westcot SE, Hatzold J, Urban MD, Richetti SK, Skuster KJ, Harm RM, Lopez Cervera R, Umemoto N, McNulty MS, Clark KJ, Hammerschmidt M, Ekker SC. Protein-Trap Insertional Mutagenesis Uncovers New Genes Involved in Zebrafish Skin Development, Including a Neuregulin 2a-Based ErbB Signaling Pathway Required during Median Fin Fold Morphogenesis. Plos One. 10: e0130688. PMID 26110643 DOI: 10.1371/journal.pone.0130688  1
2015 Craig MP, Grajevskaja V, Liao HK, Balciuniene J, Ekker SC, Park JS, Essner JJ, Balciunas D, Sumanas S. Etv2 and fli1b function together as key regulators of vasculogenesis and angiogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 865-76. PMID 25722433 DOI: 10.1161/ATVBAHA.114.304768  1
2015 Bedell VM, Ekker SC. Using engineered endonucleases to create knockout and knockin zebrafish models. Methods in Molecular Biology (Clifton, N.J.). 1239: 291-305. PMID 25408414 DOI: 10.1007/978-1-4939-1862-1_17  1
2014 Peng Y, Clark KJ, Campbell JM, Panetta MR, Guo Y, Ekker SC. Making designer mutants in model organisms. Development (Cambridge, England). 141: 4042-54. PMID 25336735 DOI: 10.1242/dev.102186  1
2014 Sun X, Ekker SC, Shelden EA, Takubo N, Wang Y, Burghardt TP. In vivo orientation of single myosin lever arms in zebrafish skeletal muscle. Biophysical Journal. 107: 1403-14. PMID 25229148 DOI: 10.1016/j.bpj.2014.07.055  1
2014 Fadel HJ, Morrison JH, Saenz DT, Fuchs JR, Kvaratskhelia M, Ekker SC, Poeschla EM. TALEN knockout of the PSIP1 gene in human cells: analyses of HIV-1 replication and allosteric integrase inhibitor mechanism. Journal of Virology. 88: 9704-17. PMID 24942577 DOI: 10.1128/JVI.01397-14  1
2014 Koep TH, Huskins WC, Clemens C, Jenkins S, Pierret C, Ekker SC, Enders FT. Influenza knowledge, attitude, and behavior survey for grade school students: design and novel assessment methodology. Journal of Community Health. 39: 1231-40. PMID 24859735 DOI: 10.1007/s10900-014-9884-0  1
2014 Wu X, Blackburn PR, Tschumper RC, Ekker SC, Jelinek DF. TALEN-mediated genetic tailoring as a tool to analyze the function of acquired mutations in multiple myeloma cells. Blood Cancer Journal. 4: e210. PMID 24813078 DOI: 10.1038/bcj.2014.32  1
2014 Cousin MA, Ebbert JO, Wiinamaki AR, Urban MD, Argue DP, Ekker SC, Klee EW. Larval zebrafish model for FDA-approved drug repositioning for tobacco dependence treatment. Plos One. 9: e90467. PMID 24658307 DOI: 10.1371/journal.pone.0090467  1
2014 Craig TA, Zhang Y, Magis AT, Funk CC, Price ND, Ekker SC, Kumar R. Detection of 1α,25-dihydroxyvitamin D-regulated miRNAs in zebrafish by whole transcriptome sequencing. Zebrafish. 11: 207-18. PMID 24650217 DOI: 10.1089/zeb.2013.0899  1
2014 He BL, Shi X, Man CH, Ma AC, Ekker SC, Chow HC, So CW, Choi WW, Zhang W, Zhang Y, Leung AY. Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia. Blood. 123: 2518-29. PMID 24591202 DOI: 10.1182/blood-2013-02-486688  1
2014 Singh M, Bhartiya D, Maini J, Sharma M, Singh AR, Kadarkaraisamy S, Rana R, Sabharwal A, Nanda S, Ramachandran A, Mittal A, Kapoor S, Sehgal P, Asad Z, Kaushik K, ... ... Ekker SC, et al. The Zebrafish GenomeWiki: a crowdsourcing approach to connect the long tail for zebrafish gene annotation. Database : the Journal of Biological Databases and Curation. 2014: bau011. PMID 24578356 DOI: 10.1093/database/bau011  1
2013 Campbell JM, Hartjes KA, Nelson TJ, Xu X, Ekker SC. New and TALENted genome engineering toolbox. Circulation Research. 113: 571-87. PMID 23948583 DOI: 10.1161/CIRCRESAHA.113.301765  1
2013 Ma AC, Lee HB, Clark KJ, Ekker SC. High efficiency In Vivo genome engineering with a simplified 15-RVD GoldyTALEN design. Plos One. 8: e65259. PMID 23734242 DOI: 10.1371/journal.pone.0065259  1
2013 Tietz Bogert PS, Huang BQ, Gradilone SA, Masyuk TV, Moulder GL, Ekker SC, Larusso NF. The zebrafish as a model to study polycystic liver disease. Zebrafish. 10: 211-7. PMID 23668934 DOI: 10.1089/zeb.2012.0825  1
2013 Patowary A, Purkanti R, Singh M, Chauhan R, Singh AR, Swarnkar M, Singh N, Pandey V, Torroja C, Clark MD, Kocher JP, Clark KJ, Stemple DL, Klee EW, Ekker SC, et al. A sequence-based variation map of zebrafish. Zebrafish. 10: 15-20. PMID 23590399 DOI: 10.1089/zeb.2012.0848  1
2013 Blackburn PR, Campbell JM, Clark KJ, Ekker SC. The CRISPR system--keeping zebrafish gene targeting fresh. Zebrafish. 10: 116-8. PMID 23536990 DOI: 10.1089/zeb.2013.9999  1
2013 Chen Z, Lee H, Henle SJ, Cheever TR, Ekker SC, Henley JR. Primary neuron culture for nerve growth and axon guidance studies in zebrafish (Danio rerio). Plos One. 8: e57539. PMID 23469201 DOI: 10.1371/journal.pone.0057539  1
2013 Koep TH, Enders FT, Pierret C, Ekker SC, Krageschmidt D, Neff KL, Lipsitch M, Shaman J, Huskins WC. Predictors of indoor absolute humidity and estimated effects on influenza virus survival in grade schools. Bmc Infectious Diseases. 13: 71. PMID 23383620 DOI: 10.1186/1471-2334-13-71  1
2013 Neff KL, Argue DP, Ma AC, Lee HB, Clark KJ, Ekker SC. Mojo Hand, a TALEN design tool for genome editing applications. Bmc Bioinformatics. 14: 1. PMID 23323762 DOI: 10.1186/1471-2105-14-1  1
2013 Ding Y, Liu W, Deng Y, Jomok B, Yang J, Huang W, Clark KJ, Zhong TP, Lin X, Ekker SC, Xu X. Trapping cardiac recessive mutants via expression-based insertional mutagenesis screening. Circulation Research. 112: 606-17. PMID 23283723 DOI: 10.1161/CIRCRESAHA.112.300603  1
2013 Khurana S, Buckley S, Schouteden S, Ekker S, Petryk A, Delforge M, Zwijsen A, Verfaillie CM. A novel role of BMP4 in adult hematopoietic stem and progenitor cell homing via Smad independent regulation of integrin-α4 expression. Blood. 121: 781-90. PMID 23243277 DOI: 10.1182/blood-2012-07-446443  1
2012 Pierret C, Sonju JD, Leicester JE, Hoody M, LaBounty TJ, Frimannsdottir KR, Ekker SC. Improvement in student science proficiency through InSciEd out. Zebrafish. 9: 155-68. PMID 23244687 DOI: 10.1089/zeb.2012.0818  1
2012 Sohni A, Mulas F, Ferrazzi F, Luttun A, Bellazzi R, Huylebroeck D, Ekker SC, Verfaillie CM. TGFβ1-induced Baf60c regulates both smooth muscle cell commitment and quiescence. Plos One. 7: e47629. PMID 23110084 DOI: 10.1371/journal.pone.0047629  1
2012 Hoffman SJ, Psaltis PJ, Clark KJ, Spoon DB, Chue CD, Ekker SC, Simari RD. An in vivo method to quantify lymphangiogenesis in zebrafish. Plos One. 7: e45240. PMID 23028871 DOI: 10.1371/journal.pone.0045240  1
2012 Bedell VM, Wang Y, Campbell JM, Poshusta TL, Starker CG, Krug RG, Tan W, Penheiter SG, Ma AC, Leung AY, Fahrenkrug SC, Carlson DF, Voytas DF, Clark KJ, Essner JJ, ... Ekker SC, et al. In vivo genome editing using a high-efficiency TALEN system. Nature. 491: 114-8. PMID 23000899 DOI: 10.1038/nature11537  1
2012 Craig TA, Zhang Y, McNulty MS, Middha S, Ketha H, Singh RJ, Magis AT, Funk C, Price ND, Ekker SC, Kumar R. Research resource: whole transcriptome RNA sequencing detects multiple 1α,25-dihydroxyvitamin D(3)-sensitive metabolic pathways in developing zebrafish. Molecular Endocrinology (Baltimore, Md.). 26: 1630-42. PMID 22734042 DOI: 10.1210/me.2012-1113  1
2012 Bedell VM, Ekker SC. Nervy vasculature. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1546-7. PMID 22699273 DOI: 10.1161/ATVBAHA.112.251272  1
2012 Hoeppner LH, Phoenix KN, Clark KJ, Bhattacharya R, Gong X, Sciuto TE, Vohra P, Suresh S, Bhattacharya S, Dvorak AM, Ekker SC, Dvorak HF, Claffey KP, Mukhopadhyay D. Revealing the role of phospholipase Cβ3 in the regulation of VEGF-induced vascular permeability. Blood. 120: 2167-73. PMID 22674805 DOI: 10.1182/blood-2012-03-417824  1
2012 McNulty MS, Bedell VM, Greenwood TM, Craig TA, Ekker SC, Kumar R. Expression of sclerostin in the developing zebrafish (Danio rerio) brain and skeleton. Gene Expression Patterns : Gep. 12: 228-35. PMID 22575304 DOI: 10.1016/j.gep.2012.04.003  1
2012 Xu J, Gao J, Li J, Xue L, Clark KJ, Ekker SC, Du SJ. Functional analysis of slow myosin heavy chain 1 and myomesin-3 in sarcomere organization in zebrafish embryonic slow muscles. Journal of Genetics and Genomics = Yi Chuan Xue Bao. 39: 69-80. PMID 22361506 DOI: 10.1016/j.jgg.2012.01.005  1
2012 Liao HK, Wang Y, Noack Watt KE, Wen Q, Breitbach J, Kemmet CK, Clark KJ, Ekker SC, Essner JJ, McGrail M. Tol2 gene trap integrations in the zebrafish amyloid precursor protein genes appa and aplp2 reveal accumulation of secreted APP at the embryonic veins. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 241: 415-25. PMID 22275008 DOI: 10.1002/dvdy.23725  1
2012 Bedell VM, Person AD, Larson JD, McLoon A, Balciunas D, Clark KJ, Neff KI, Nelson KE, Bill BR, Schimmenti LA, Beiraghi S, Ekker SC. The lineage-specific gene ponzr1 is essential for zebrafish pronephric and pharyngeal arch development. Development (Cambridge, England). 139: 793-804. PMID 22274699 DOI: 10.1242/dev.071720  1
2012 Klee EW, Schneider H, Clark KJ, Cousin MA, Ebbert JO, Hooten WM, Karpyak VM, Warner DO, Ekker SC. Zebrafish: a model for the study of addiction genetics. Human Genetics. 131: 977-1008. PMID 22207143 DOI: 10.1007/s00439-011-1128-0  1
2012 Clark KJ, Argue DP, Petzold AM, Ekker SC. zfishbook: connecting you to a world of zebrafish revertible mutants. Nucleic Acids Research. 40: D907-11. PMID 22067444 DOI: 10.1093/nar/gkr957  1
2011 Ma AC, Fung TK, Lin RH, Chung MI, Yang D, Ekker SC, Leung AY. Methionine aminopeptidase 2 is required for HSC initiation and proliferation. Blood. 118: 5448-57. PMID 21937698 DOI: 10.1182/blood-2011-04-350173  1
2011 Clark KJ, Voytas DF, Ekker SC. A TALE of two nucleases: gene targeting for the masses? Zebrafish. 8: 147-9. PMID 21929364 DOI: 10.1089/zeb.2011.9993  1
2011 Clark KJ, Urban MD, Skuster KJ, Ekker SC. Transgenic zebrafish using transposable elements. Methods in Cell Biology. 104: 137-49. PMID 21924161 DOI: 10.1016/B978-0-12-374814-0.00008-2  1
2011 Ding Y, Sun X, Huang W, Hoage T, Redfield M, Kushwaha S, Sivasubbu S, Lin X, Ekker S, Xu X. Haploinsufficiency of target of rapamycin attenuates cardiomyopathies in adult zebrafish Circulation Research. 109: 658-669. PMID 21757652 DOI: 10.1161/CIRCRESAHA.111.248260  1
2011 Bedell VM, Westcot SE, Ekker SC. Lessons from morpholino-based screening in zebrafish. Briefings in Functional Genomics. 10: 181-8. PMID 21746693 DOI: 10.1093/bfgp/elr021  1
2011 Clark KJ, Boczek NJ, Ekker SC. Stressing zebrafish for behavioral genetics. Reviews in the Neurosciences. 22: 49-62. PMID 21615261 DOI: 10.1515/RNS.2011.007  1
2011 Clark KJ, Balciunas D, Pogoda HM, Ding Y, Westcot SE, Bedell VM, Greenwood TM, Urban MD, Skuster KJ, Petzold AM, Ni J, Nielsen AL, Patowary A, Scaria V, Sivasubbu S, ... ... Ekker SC, et al. In vivo protein trapping produces a functional expression codex of the vertebrate proteome. Nature Methods. 8: 506-15. PMID 21552255 DOI: 10.1038/nmeth.1606  1
2011 Klee EW, Ebbert JO, Schneider H, Hurt RD, Ekker SC. Zebrafish for the study of the biological effects of nicotine. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 13: 301-12. PMID 21385906 DOI: 10.1093/ntr/ntr010  1
2011 Buckley SM, Ulloa-Montoya F, Abts D, Oostendorp RA, Dzierzak E, Ekker SC, Verfaillie CM. Maintenance of HSC by Wnt5a secreting AGM-derived stromal cell line. Experimental Hematology. 39: 114-123.e1-5. PMID 20933051 DOI: 10.1016/j.exphem.2010.09.010  1
2011 Alexandre D, Alonzeau J, Bill BR, Ekker SC, Waschek JA. Expression analysis of PAC1-R and PACAP genes in zebrafish embryos. Journal of Molecular Neuroscience : Mn. 43: 94-100. PMID 20526695 DOI: 10.1007/s12031-010-9397-y  1
2010 Wang Y, Kaiser MS, Larson JD, Nasevicius A, Clark KJ, Wadman SA, Roberg-Perez SE, Ekker SC, Hackett PB, McGrail M, Essner JJ. Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis. Development (Cambridge, England). 137: 3119-28. PMID 20736288 DOI: 10.1242/dev.048785  1
2010 He Z, Zhang H, Zhang X, Xie D, Chen Y, Wangensteen KJ, Ekker SC, Firpo M, Liu C, Xiang D, Zi X, Hui L, Yang G, Ding X, Hu Y, et al. Liver xeno-repopulation with human hepatocytes in Fah-/-Rag2-/- mice after pharmacological immunosuppression. The American Journal of Pathology. 177: 1311-9. PMID 20651238 DOI: 10.2353/ajpath.2010.091154  1
2010 Huang X, Guo H, Tammana S, Jung YC, Mellgren E, Bassi P, Cao Q, Tu ZJ, Kim YC, Ekker SC, Wu X, Wang SM, Zhou X. Gene transfer efficiency and genome-wide integration profiling of Sleeping Beauty, Tol2, and piggyBac transposons in human primary T cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1803-13. PMID 20606646 DOI: 10.1038/mt.2010.141  1
2010 Petzold AM, Bedell VM, Boczek NJ, Essner JJ, Balciunas D, Clark KJ, Ekker SC. SCORE imaging: specimen in a corrected optical rotational enclosure. Zebrafish. 7: 149-54. PMID 20528262 DOI: 10.1089/zeb.2010.0660  1
2010 Person AD, Beiraghi S, Sieben CM, Hermanson S, Neumann AN, Robu ME, Schleiffarth JR, Billington CJ, van Bokhoven H, Hoogeboom JM, Mazzeu JF, Petryk A, Schimmenti LA, Brunner HG, Ekker SC, et al. WNT5A mutations in patients with autosomal dominant Robinow syndrome. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 327-37. PMID 19918918 DOI: 10.1002/dvdy.22156  1
2009 Petzold AM, Balciunas D, Sivasubbu S, Clark KJ, Bedell VM, Westcot SE, Myers SR, Moulder GL, Thomas MJ, Ekker SC. Nicotine response genetics in the zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 106: 18662-7. PMID 19858493 DOI: 10.1073/pnas.0908247106  1
2009 Keng VW, Ryan BJ, Wangensteen KJ, Balciunas D, Schmedt C, Ekker SC, Largaespada DA. Efficient transposition of Tol2 in the mouse germline. Genetics. 183: 1565-73. PMID 19805821 DOI: 10.1534/genetics.109.100768  1
2009 Petzold AM, Clark KJ, Ekker SC. Spotlight on the future of scientific publication. Zebrafish. 6: 215-7. PMID 19761376 DOI: 10.1089/zeb.2009.9992  1
2009 Ekker SC, Hutson LD, Fields M. The art and science of zebrafish in the classroom-an interview with melanie fields Zebrafish. 6: 121-126. PMID 19537939 DOI: 10.1089/zeb.2009.9995  1
2009 Bill BR, Petzold AM, Clark KJ, Schimmenti LA, Ekker SC. A primer for morpholino use in zebrafish. Zebrafish. 6: 69-77. PMID 19374550 DOI: 10.1089/zeb.2008.0555  1
2009 Ekker SC, Bedell VM. The ins and outs of VEGF signaling. Blood. 113: 2123-4. PMID 19264924 DOI: 10.1182/blood-2008-11-189746  1
2009 Shibasaki Y, Kim BS, Young AJ, Mcloon AL, Ekker SC, Taton TA. Crosslinked, glassy styrenic surfactants stabilize quantum dots against environmental extremes Journal of Materials Chemistry. 19: 6324-6327. DOI: 10.1039/b902275a  1
2008 Ekker SC, Parichy DM, Cheng KC. Research implications of pigment biology in zebrafish. Zebrafish. 5: 233-5. PMID 19133820 DOI: 10.1089/zeb.2008.9981  1
2008 Ni J, Clark KJ, Fahrenkrug SC, Ekker SC. Transposon tools hopping in vertebrates. Briefings in Functional Genomics & Proteomics. 7: 444-53. PMID 19109308 DOI: 10.1093/bfgp/eln049  1
2008 Okamoto H. An interview with Hitoshi Okamoto, M.D., Ph.D. Interview by Stephen C. Ekker. Zebrafish. 5: 155-8. PMID 18945196 DOI: 10.1089/zeb.2008.9983  1
2008 Ekker SC. All eyes on zebrafish. Zebrafish. 5: 153. PMID 18945195 DOI: 10.1089/zeb.2008.9984  1
2008 Bill BR, Balciunas D, McCarra JA, Young ED, Xiong T, Spahn AM, Garcia-Lecea M, Korzh V, Ekker SC, Schimmenti LA. Development and Notch signaling requirements of the zebrafish choroid plexus. Plos One. 3: e3114. PMID 18769591 DOI: 10.1371/journal.pone.0003114  1
2008 Ekker SC. Down on the (fish) farm. Zebrafish. 5: 139-40. PMID 18554178 DOI: 10.1089/zeb.2008.9990  1
2008 Ekker SC. Zinc finger-based knockout punches for zebrafish genes. Zebrafish. 5: 121-3. PMID 18554175 DOI: 10.1089/zeb.2008.9988  1
2008 Chen J, Ekker SC. Modulation of gene expression in the study of zebrafish development - A discussion with James Chen, Ph.D Zebrafish. 5: 93-96. PMID 18554172 DOI: 10.1089/zeb.2008.9993  1
2008 Wangensteen KJ, Wilber A, Keng VW, He Z, Matise I, Wangensteen L, Carson CM, Chen Y, Steer CJ, McIvor RS, Largaespada DA, Wang X, Ekker SC. A facile method for somatic, lifelong manipulation of multiple genes in the mouse liver. Hepatology (Baltimore, Md.). 47: 1714-24. PMID 18435462 DOI: 10.1002/hep.22195  1
2008 Cheng KC. Views on four key questions about zebrafish research. Zebrafish. 5: 9-24. PMID 18399790 DOI: 10.1089/zeb.2008.9996  1
2008 Ekker SC. Looking to the future. Zebrafish. 5: 1-2. PMID 18399788 DOI: 10.1089/zeb.2008.9994  1
2008 Knowlton MN, Li T, Ren Y, Bill BR, Ellis LB, Ekker SC. A PATO-compliant zebrafish screening database (MODB): management of morpholino knockdown screen information. Bmc Bioinformatics. 9: 7. PMID 18179718 DOI: 10.1186/1471-2105-9-7  1
2008 Ekker S. The three musketeers of HSC development Blood. 111: 4834-4835. DOI: 10.1182/blood-2008-02-138982  1
2007 Ekker SC, Stemple DL, Clark M, Chien CB, Rasooly RS, Javois LC. Zebrafish genome project: bringing new biology to the vertebrate genome field. Zebrafish. 4: 239-51. PMID 18284331 DOI: 10.1089/zeb.2007.9979  1
2007 Sivasubbu S, Balciunas D, Amsterdam A, Ekker SC. Insertional mutagenesis strategies in zebrafish. Genome Biology. 8: S9. PMID 18047701 DOI: 10.1186/gb-2007-8-s1-s9  1
2007 Wang L, Dutta SK, Kojima T, Xu X, Khosravi-Far R, Ekker SC, Mukhopadhyay D. Neuropilin-1 modulates p53/caspases axis to promote endothelial cell survival. Plos One. 2: e1161. PMID 18000534 DOI: 10.1371/journal.pone.0001161  1
2007 Alvarez Y, Cederlund ML, Cottell DC, Bill BR, Ekker SC, Torres-Vazquez J, Weinstein BM, Hyde DR, Vihtelic TS, Kennedy BN. Genetic determinants of hyaloid and retinal vasculature in zebrafish. Bmc Developmental Biology. 7: 114. PMID 17937808 DOI: 10.1186/1471-213X-7-114  1
2007 Robu ME, Larson JD, Nasevicius A, Beiraghi S, Brenner C, Farber SA, Ekker SC. p53 activation by knockdown technologies. Plos Genetics. 3: e78. PMID 17530925 DOI: 10.1371/journal.pgen.0030078  1
2007 Schleiffarth JR, Person AD, Martinsen BJ, Sukovich DJ, Neumann A, Baker CV, Lohr JL, Cornfield DN, Ekker SC, Petryk A. Wnt5a is required for cardiac outflow tract septation in mice. Pediatric Research. 61: 386-91. PMID 17515859 DOI: 10.1203/pdr.0b013e3180323810  1
2007 Wilber A, Wangensteen KJ, Chen Y, Zhuo L, Frandsen JL, Bell JB, Chen ZJ, Ekker SC, McIvor RS, Wang X. Messenger RNA as a source of transposase for sleeping beauty transposon-mediated correction of hereditary tyrosinemia type I. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1280-7. PMID 17440442 DOI: 10.1038/sj.mt.6300160  1
2007 Patterson LJ, Gering M, Eckfeldt CE, Green AR, Verfaillie CM, Ekker SC, Patient R. The transcription factors Scl and Lmo2 act together during development of the hemangioblast in zebrafish. Blood. 109: 2389-98. PMID 17090656 DOI: 10.1182/blood-2006-02-003087  1
2006 Pickart MA, Klee EW, Nielsen AL, Sivasubbu S, Mendenhall EM, Bill BR, Chen E, Eckfeldt CE, Knowlton M, Robu ME, Larson JD, Deng Y, Schimmenti LA, Ellis LB, Verfaillie CM, ... ... Ekker SC, et al. Genome-wide reverse genetics framework to identify novel functions of the vertebrate secretome. Plos One. 1: e104. PMID 17218990 DOI: 10.1371/journal.pone.0000104  1
2006 Balciunas D, Wangensteen KJ, Wilber A, Bell J, Geurts A, Sivasubbu S, Wang X, Hackett PB, Largaespada DA, McIvor RS, Ekker SC. Harnessing a high cargo-capacity transposon for genetic applications in vertebrates. Plos Genetics. 2: e169. PMID 17096595 DOI: 10.1371/journal.pgen.0020169  1
2006 Sivasubbu S, Balciunas D, Davidson AE, Pickart MA, Hermanson SB, Wangensteen KJ, Wolbrink DC, Ekker SC. Gene-breaking transposon mutagenesis reveals an essential role for histone H2afza in zebrafish larval development. Mechanisms of Development. 123: 513-29. PMID 16859902 DOI: 10.1016/j.mod.2006.06.002  1
2006 Chen E, Larson JD, Ekker SC. Functional analysis of zebrafish microfibril-associated glycoprotein-1 (Magp1) in vivo reveals roles for microfibrils in vascular development and function. Blood. 107: 4364-74. PMID 16469878 DOI: 10.1182/blood-2005-02-0789  1
2006 Kwan TT, Liang R, Verfaillie CM, Ekker SC, Chan LC, Lin S, Leung AY. Regulation of primitive hematopoiesis in zebrafish embryos by the death receptor gene. Experimental Hematology. 34: 27-34. PMID 16413388 DOI: 10.1016/j.exphem.2005.09.017  1
2006 Essner JJ, Chen E, Ekker SC. Syndecan-2. The International Journal of Biochemistry & Cell Biology. 38: 152-6. PMID 16198615 DOI: 10.1016/j.biocel.2005.08.012  1
2005 Balciunas D, Ekker SC. Trapping fish genes with transposons. Zebrafish. 1: 335-41. PMID 18248211 DOI: 10.1089/zeb.2005.1.335  1
2005 Wilber A, Frandsen JL, Wangensteen KJ, Ekker SC, Wang X, McIvor RS. Dynamic gene expression after systemic delivery of plasmid DNA as determined by in vivo bioluminescence imaging. Human Gene Therapy. 16: 1325-32. PMID 16259566 DOI: 10.1089/hum.2005.16.1325  1
2005 Kim HJ, Schleiffarth JR, Jessurun J, Sumanas S, Petryk A, Lin S, Ekker SC. Wnt5 signaling in vertebrate pancreas development. Bmc Biology. 3: 23. PMID 16246260 DOI: 10.1186/1741-7007-3-23  1
2005 Ohlfest JR, Demorest ZL, Motooka Y, Vengco I, Oh S, Chen E, Scappaticci FA, Saplis RJ, Ekker SC, Low WC, Freese AB, Largaespada DA. Combinatorial antiangiogenic gene therapy by nonviral gene transfer using the sleeping beauty transposon causes tumor regression and improves survival in mice bearing intracranial human glioblastoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 778-88. PMID 16150649 DOI: 10.1016/j.ymthe.2005.07.689  1
2005 Hackett PB, Ekker SC, Largaespada DA, McIvor RS. Sleeping beauty transposon-mediated gene therapy for prolonged expression. Advances in Genetics. 54: 189-232. PMID 16096013 DOI: 10.1016/S0065-2660(05)54009-4  1
2005 Eckfeldt CE, Mendenhall EM, Flynn CM, Wang TF, Pickart MA, Grindle SM, Ekker SC, Verfaillie CM. Functional analysis of human hematopoietic stem cell gene expression using zebrafish. Plos Biology. 3: e254. PMID 16089502 DOI: 10.1371/journal.pbio.0030254  1
2005 Chen E, Stringer SE, Rusch MA, Selleck SB, Ekker SC. A unique role for 6-O sulfation modification in zebrafish vascular development. Developmental Biology. 284: 364-76. PMID 16009360 DOI: 10.1016/j.ydbio.2005.05.032  1
2005 Klee EW, Shim KJ, Pickart MA, Ekker SC, Ellis LB. AMOD: a morpholino oligonucleotide selection tool. Nucleic Acids Research. 33: W506-11. PMID 15980523 DOI: 10.1093/nar/gki453  1
2005 Leung AY, Mendenhall EM, Kwan TT, Liang R, Eckfeldt C, Chen E, Hammerschmidt M, Grindley S, Ekker SC, Verfaillie CM. Characterization of expanded intermediate cell mass in zebrafish chordin morphant embryos. Developmental Biology. 277: 235-54. PMID 15572152 DOI: 10.1016/j.ydbio.2004.09.032  1
2004 Hermanson S, Davidson AE, Sivasubbu S, Balciunas D, Ekker SC. Sleeping Beauty transposon for efficient gene delivery. Methods in Cell Biology. 77: 349-62. PMID 15602921 DOI: 10.1016/S0091-679X(04)77019-3  1
2004 Ekker SC. Nonconventional antisense in zebrafish for functional genomics applications. Methods in Cell Biology. 77: 121-36. PMID 15602909 DOI: 10.1016/S0091-679X(04)77007-7  1
2004 Chen E, Ekker SC. Zebrafish as a genomics research model. Current Pharmaceutical Biotechnology. 5: 409-13. PMID 15544488 DOI: 10.2174/1389201043376652  1
2004 Pickart MA, Sivasubbu S, Nielsen AL, Shriram S, King RA, Ekker SC. Functional genomics tools for the analysis of zebrafish pigment. Pigment Cell Research / Sponsored by the European Society For Pigment Cell Research and the International Pigment Cell Society. 17: 461-70. PMID 15357832 DOI: 10.1111/j.1600-0749.2004.00189.x  1
2004 Balciunas D, Davidson AE, Sivasubbu S, Hermanson SB, Welle Z, Ekker SC. Enhancer trapping in zebrafish using the Sleeping Beauty transposon. Bmc Genomics. 5: 62. PMID 15347431 DOI: 10.1186/1471-2164-5-62  1
2004 Larson JD, Wadman SA, Chen E, Kerley L, Clark KJ, Eide M, Lippert S, Nasevicius A, Ekker SC, Hackett PB, Essner JJ. Expression of VE-cadherin in zebrafish embryos: a new tool to evaluate vascular development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 231: 204-13. PMID 15305301 DOI: 10.1002/dvdy.20102  1
2004 Klee EW, Carlson DF, Fahrenkrug SC, Ekker SC, Ellis LB. Identifying secretomes in people, pufferfish and pigs. Nucleic Acids Research. 32: 1414-21. PMID 14990746 DOI: 10.1093/nar/gkh286  1
2004 Chen E, Hermanson S, Ekker SC. Syndecan-2 is essential for angiogenic sprouting during zebrafish development. Blood. 103: 1710-9. PMID 14592839 DOI: 10.1182/blood-2003-06-1783  1
2003 Davidson AE, Balciunas D, Mohn D, Shaffer J, Hermanson S, Sivasubbu S, Cliff MP, Hackett PB, Ekker SC. Efficient gene delivery and gene expression in zebrafish using the Sleeping Beauty transposon. Developmental Biology. 263: 191-202. PMID 14597195 DOI: 10.1016/j.ydbio.2003.07.013  1
2002 Sumanas S, Kim HJ, Hermanson SB, Ekker SC. Lateral line, nervous system, and maternal expression of Frizzled 7a during zebrafish embryogenesis. Mechanisms of Development. 115: 107-11. PMID 12049772 DOI: 10.1016/S0925-4773(02)00084-9  1
2002 Dupuy AJ, Clark K, Carlson CM, Fritz S, Davidson AE, Markley KM, Finley K, Fletcher CF, Ekker SC, Hackett PB, Horn S, Largaespada DA. Mammalian germ-line transgenesis by transposition. Proceedings of the National Academy of Sciences of the United States of America. 99: 4495-9. PMID 11904379 DOI: 10.1073/pnas.062630599  1
2001 Nasevicius A, Ekker SC. The zebrafish as a novel system for functional genomics and therapeutic development applications. Current Opinion in Molecular Therapeutics. 3: 224-8. PMID 11497344  1
2001 Bingham S, Nasevicius A, Ekker SC, Chandrasekhar A. Sonic hedgehog and tiggy-winkle hedgehog cooperatively induce zebrafish branchiomotor neurons. Genesis (New York, N.Y. : 2000). 30: 170-4. PMID 11477700 DOI: 10.1002/gene.1057  1
2001 Etheridge LA, Wu T, Liang JO, Ekker SC, Halpern ME. Floor plate develops upon depletion of tiggy-winkle and sonic hedgehog. Genesis (New York, N.Y. : 2000). 30: 164-9. PMID 11477699 DOI: 10.1002/gene.1056  1
2001 Klee EW, Ekker SC, Ellis LB. Target selection for Danio rerio functional genomics. Genesis (New York, N.Y. : 2000). 30: 123-5. PMID 11477688 DOI: 10.1002/gene.1045  1
2001 Sumanas S, Ekker SC. Xenopus frizzled-7 morphant displays defects in dorsoventral patterning and convergent extension movements during gastrulation. Genesis (New York, N.Y. : 2000). 30: 119-22. PMID 11477687 DOI: 10.1002/gene.1044  1
2001 Sumanas S, Kim HJ, Hermanson S, Ekker SC. Zebrafish frizzled-2 morphant displays defects in body axis elongation. Genesis (New York, N.Y. : 2000). 30: 114-8. PMID 11477686 DOI: 10.1002/gene.1043  1
2001 Ekker SC, Larson JD. Morphant technology in model developmental systems. Genesis (New York, N.Y. : 2000). 30: 89-93. PMID 11477681 DOI: 10.1002/gene.1038  1
2001 Finley KR, Davidson AE, Ekker SC. Three-color imaging using fluorescent proteins in living zebrafish embryos. Biotechniques. 31: 66-70, 72. PMID 11464522  1
2001 Sumanas S, Ekker SC. Xenopus frizzled-5: a frizzled family member expressed exclusively in the neural retina of the developing eye. Mechanisms of Development. 103: 133-6. PMID 11335120 DOI: 10.1016/S0925-4773(01)00327-6  1
2001 Ross JJ, Shimmi O, Vilmos P, Petryk A, Kim H, Gaudenz K, Hermanson S, Ekker SC, O'Connor MB, Marsh JL. Twisted gastrulation is a conserved extracellular BMP antagonist. Nature. 410: 479-83. PMID 11260716 DOI: 10.1038/35068578  1
2000 Ekker SC. Morphants: a new systematic vertebrate functional genomics approach. Yeast (Chichester, England). 17: 302-306. PMID 11119307 DOI: 10.1002/1097-0061(200012)17:4<302::AID-YEA53>3.0.CO;2-#  1
2000 Nasevicius A, Larson J, Ekker SC. Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant. Yeast (Chichester, England). 17: 294-301. PMID 11119306 DOI: 10.1002/1097-0061(200012)17:4<294::AID-YEA54>3.0.CO;2-5  1
2000 Nasevicius A, Ekker SC. Effective targeted gene 'knockdown' in zebrafish. Nature Genetics. 26: 216-20. PMID 11017081 DOI: 10.1038/79951  1
2000 Sumanas S, Strege P, Heasman J, Ekker SC. The putative wnt receptor Xenopus frizzled-7 functions upstream of beta-catenin in vertebrate dorsoventral mesoderm patterning. Development (Cambridge, England). 127: 1981-90. PMID 10751186  1
2000 Nasevicius A, Hyatt TM, Hermanson SB, Ekker SC. Sequence, expression, and location of zebrafish frizzled 10. Mechanisms of Development. 92: 311-4. PMID 10727872 DOI: 10.1016/S0925-4773(00)00244-6  1
1999 Hyatt TM, Ekker SC. Vectors and techniques for ectopic gene expression in zebrafish. Methods in Cell Biology. 59: 117-26. PMID 9891358  1
1998 Nasevicius A, Hyatt T, Kim H, Guttman J, Walsh E, Sumanas S, Wang Y, Ekker SC. Evidence for a frizzled-mediated wnt pathway required for zebrafish dorsal mesoderm formation. Development (Cambridge, England). 125: 4283-92. PMID 9753682  1
1996 Porter JA, Ekker SC, Park WJ, von Kessler DP, Young KE, Chen CH, Ma Y, Woods AS, Cotter RJ, Koonin EV, Beachy PA. Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain. Cell. 86: 21-34. PMID 8689684 DOI: 10.1016/S0092-8674(00)80074-4  1
1995 Porter JA, von Kessler DP, Ekker SC, Young KE, Lee JJ, Moses K, Beachy PA. The product of hedgehog autoproteolytic cleavage active in local and long-range signalling. Nature. 374: 363-6. PMID 7885476 DOI: 10.1038/374363a0  1
1995 Lai CJ, Ekker SC, Beachy PA, Moon RT. Patterning of the neural ectoderm of Xenopus laevis by the amino-terminal product of hedgehog autoproteolytic cleavage. Development (Cambridge, England). 121: 2349-60. PMID 7671801  1
1995 Ekker SC, McGrew LL, Lai CJ, Lee JJ, von Kessler DP, Moon RT, Beachy PA. Distinct expression and shared activities of members of the hedgehog gene family of Xenopus laevis. Development (Cambridge, England). 121: 2337-47. PMID 7671800  1
1995 Ekker SC, Ungar AR, Greenstein P, von Kessler DP, Porter JA, Moon RT, Beachy PA. Patterning activities of vertebrate hedgehog proteins in the developing eye and brain. Current Biology : Cb. 5: 944-55. PMID 7583153 DOI: 10.1016/S0960-9822(95)00185-0  1
1994 Lee JJ, Ekker SC, von Kessler DP, Porter JA, Sun BI, Beachy PA. Autoproteolysis in hedgehog protein biogenesis. Science (New York, N.Y.). 266: 1528-37. PMID 7985023  1
1994 Ekker SC, Jackson DG, von Kessler DP, Sun BI, Young KE, Beachy PA. The degree of variation in DNA sequence recognition among four Drosophila homeotic proteins. The Embo Journal. 13: 3551-60. PMID 7914870  1
1993 Beachy PA, Varkey J, Young KE, von Kessler DP, Sun BI, Ekker SC. Cooperative binding of an Ultrabithorax homeodomain protein to nearby and distant DNA sites. Molecular and Cellular Biology. 13: 6941-56. PMID 8105373  1
1992 Ekker SC, von Kessler DP, Beachy PA. Differential DNA sequence recognition is a determinant of specificity in homeotic gene action. The Embo Journal. 11: 4059-72. PMID 1356765  1
1991 Ekker SC, Young KE, von Kessler DP, Beachy PA. Optimal DNA sequence recognition by the Ultrabithorax homeodomain of Drosophila. The Embo Journal. 10: 1179-86. PMID 1673656  1
Show low-probability matches.