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JiaBei Lin - Publications

Affiliations: 
2016- University of Pennsylvania, Philadelphia, PA, United States 
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lin J, Carman PJ, Gambogi CW, Kendsersky NM, Chuang E, Gates SN, Yokom AL, Rizo AN, Southworth DR, Shorter J. Design principles to tailor Hsp104 therapeutics. Biorxiv : the Preprint Server For Biology. PMID 38712168 DOI: 10.1101/2024.04.26.591398  0.639
2023 Guo L, Mann JR, Mauna JC, Copley KE, Wang H, Rubien JD, Odeh HM, Lin J, Lee BL, Ganser L, Robinson E, Kim KM, Murthy AC, Paul T, Portz B, et al. Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains. Biorxiv : the Preprint Server For Biology. PMID 37732211 DOI: 10.1101/2023.09.04.555754  0.721
2023 Mack KL, Kim H, Barbieri EM, Lin J, Braganza S, Jackrel ME, DeNizio JE, Yan X, Chuang E, Tariq A, Cupo RR, Castellano LM, Caldwell KA, Caldwell GA, Shorter J. Tuning Hsp104 specificity to selectively detoxify α-synuclein. Molecular Cell. PMID 37625404 DOI: 10.1016/j.molcel.2023.07.029  0.754
2022 Lin J, Shorter J, Lucius AL. AAA+ proteins: one motor, multiple ways to work. Biochemical Society Transactions. PMID 35356966 DOI: 10.1042/BST20200350  0.732
2021 Huang L, Agrawal T, Zhu G, Yu S, Tao L, Lin J, Marmorstein R, Shorter J, Yang X. DAXX represents a new type of protein-folding enabler. Nature. PMID 34408321 DOI: 10.1038/s41586-021-03824-5  0.571
2020 March ZM, Sweeney K, Kim H, Yan X, Castellano LM, Jackrel ME, Lin J, Chuang E, Gomes E, Willicott CW, Michalska K, Jedrzejczak RP, Joachimiak A, Caldwell KA, Caldwell GA, et al. Therapeutic genetic variation revealed in diverse Hsp104 homologs. Elife. 9. PMID 33319748 DOI: 10.7554/eLife.57457  0.825
2020 Lopez KE, Rizo AN, Tse E, Lin J, Scull NW, Thwin AC, Lucius AL, Shorter J, Southworth DR. Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis. Nature Structural & Molecular Biology. PMID 32313240 DOI: 10.1038/S41594-020-0409-5  0.749
2020 Ye X, Lin J, Mayne L, Shorter J, Englander SW. Structural and kinetic basis for the regulation and potentiation of Hsp104 function. Proceedings of the National Academy of Sciences of the United States of America. PMID 32277033 DOI: 10.1073/Pnas.1921968117  0.644
2019 Jones RD, Enam C, Ibarra R, Borror HR, Mostoller KE, Fredrickson EK, Lin J, Chuang E, March Z, Shorter J, Ravid T, Kleiger G, Gardner RG. The extent of Ssa1/Ssa2 Hsp70 chaperone involvement in nuclear protein quality control degradation varies with the substrate. Molecular Biology of the Cell. mbcE18020121. PMID 31825716 DOI: 10.1091/Mbc.E18-02-0121  0.8
2019 Tariq A, Lin J, Jackrel ME, Hesketh CD, Carman PJ, Mack KL, Weitzman R, Gambogi C, Hernandez Murillo OA, Sweeny EA, Gurpinar E, Yokom AL, Gates SN, Yee K, Sudesh S, et al. Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and α-Synuclein Proteotoxicity. Cell Reports. 28: 2080-2095.e6. PMID 31433984 DOI: 10.1016/J.Celrep.2019.07.069  0.791
2019 Rizo AN, Lin J, Gates SN, Tse E, Bart SM, Castellano LM, DiMaio F, Shorter J, Southworth DR. Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase. Nature Communications. 10: 2393. PMID 31160557 DOI: 10.1038/S41467-019-10150-Y  0.807
2019 Durie CL, Lin J, Scull NW, Mack KL, Jackrel ME, Sweeny EA, Castellano LM, Shorter J, Lucius AL. Hsp104 and Potentiated Variants Can Operate as Distinct Nonprocessive Translocases. Biophysical Journal. PMID 31027887 DOI: 10.1016/J.Bpj.2019.03.035  0.79
2019 Ye X, Lin J, Mayne L, Shorter J, Englander SW. Hydrogen exchange reveals Hsp104 architecture, structural dynamics, and energetics in physiological solution. Proceedings of the National Academy of Sciences of the United States of America. PMID 30918129 DOI: 10.1073/Pnas.1816184116  0.671
2019 Ye X, Lin J, Mayne LC, Shorter J, Englander SW. Mechanism of Hsp104 Function Potentiation Studied by Hydrogen-Deuterium Exchange Detected by Mass Spectrometry (HX-Ms) Biophysical Journal. 116: 484a. DOI: 10.1016/J.Bpj.2018.11.2612  0.511
2018 Tariq A, Lin J, Noll MM, Torrente MP, Mack KL, Murillo OH, Jackrel ME, Shorter J. Potentiating Hsp104 activity via phosphomimetic mutations in the middle domain. Fems Yeast Research. 18. PMID 29788207 DOI: 10.1093/Femsyr/Foy042  0.788
2018 Weaver CL, Jackrel ME, Lin J, Mack KL, Sweeny E, Duran EC, Shorter J, Lucius AL. Kinetic Mechanism of ATP-Dependent Disaggregating Motor Saccharomyces cerevisiae Hsp104 Biophysical Journal. 114: 553a. DOI: 10.1016/J.Bpj.2017.11.3021  0.751
2017 Gates SN, Yokom AL, Lin J, Jackrel ME, Rizo AN, Kendsersky NM, Buell CE, Sweeny EA, Mack KL, Chuang E, Torrente MP, Su M, Shorter J, Southworth DR. Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104. Science (New York, N.Y.). PMID 28619716 DOI: 10.1126/Science.Aan1052  0.773
2017 Weaver CL, Duran EC, Mack KL, Lin J, Jackrel ME, Sweeny EA, Shorter J, Lucius AL. Avidity for polypeptide binding by nucleotide-bound Hsp104 structures. Biochemistry. PMID 28379007 DOI: 10.1021/Acs.Biochem.7B00225  0.778
2016 Lin J, Lucius AL. Examination of ClpB quaternary structure and linkage to nucleotide binding. Biochemistry. PMID 26891079 DOI: 10.1016/J.Bpj.2015.11.1129  0.721
2015 Lin J, Lucius AL. Analysis of Linked Equilibria. Methods in Enzymology. 562: 161-86. PMID 26412651 DOI: 10.1016/Bs.Mie.2015.07.003  0.692
2015 Lin J, Lucius AL. Examination of the dynamic assembly equilibrium for E. coli ClpB. Proteins. PMID 26313457 DOI: 10.1002/Prot.24914  0.728
2015 Li T, Weaver CL, Lin J, Duran EC, Miller JM, Lucius AL. Escherichia coli ClpB is a non-processive polypeptide translocase. The Biochemical Journal. 470: 39-52. PMID 26251445 DOI: 10.1042/Bj20141457  0.699
2015 Li T, Lin J, Lucius AL. Examination of polypeptide substrate specificity for Escherichia coli ClpB. Proteins. 83: 117-34. PMID 25363713 DOI: 10.1002/Prot.24710  0.665
2015 Lin J, Lucius AL. Thermodynamic and Hydrodynamic Examination of ClpB Assembly Biophysical Journal. 108: 222a. DOI: 10.1016/J.Bpj.2014.11.1224  0.737
2014 Fancy RM, Wang L, Napier T, Lin J, Jing G, Lucius AL, McDonald JM, Zhou T, Song Y. Characterization of calmodulin-Fas death domain interaction: an integrated experimental and computational study. Biochemistry. 53: 2680-8. PMID 24702583 DOI: 10.1021/Bi500228H  0.64
2013 Miller JM, Lin J, Li T, Lucius AL. E. coli ClpA catalyzed polypeptide translocation is allosterically controlled by the protease ClpP. Journal of Molecular Biology. 425: 2795-812. PMID 23639359 DOI: 10.1016/J.Jmb.2013.04.019  0.719
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