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Onur Dagliyan, Ph.D. - Publications

Neurobiology Harvard Medical School, Boston, MA, United States 
Cell Signaling

19/27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Yap EL, Pettit NL, Davis CP, Nagy MA, Harmin DA, Golden E, Dagliyan O, Lin C, Rudolph S, Sharma N, Griffith EC, Harvey CD, Greenberg ME. Bidirectional perisomatic inhibitory plasticity of a Fos neuronal network. Nature. PMID 33299180 DOI: 10.1038/s41586-020-3031-0  0.52
2020 Wu HD, Kikuchi M, Dagliyan O, Aragaki AK, Nakamura H, Dokholyan NV, Umehara T, Inoue T. Rational design and implementation of a chemically inducible heterotrimerization system. Nature Methods. PMID 32747768 DOI: 10.1038/s41592-020-0913-x  1
2020 Ozkan-Dagliyan I, Diehl JN, George SD, Schaefer A, Papke B, Klotz-Noack K, Waters AM, Goodwin CM, Gautam P, Pierobon M, Peng S, Gilbert TSK, Lin KH, Dagliyan O, Wennerberg K, et al. Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers. Cell Reports. 31: 107764. PMID 32553168 DOI: 10.1016/j.celrep.2020.107764  0.32
2019 Dagliyan O, Dokholyan NV, Hahn KM. Engineering proteins for allosteric control by light or ligands. Nature Protocols. PMID 31076662 DOI: 10.1038/s41596-019-0165-3  1
2019 Dagliyan O, Hahn KM. Controlling protein conformation with light. Current Opinion in Structural Biology. 57: 17-22. PMID 30849716 DOI: 10.1016/  1
2018 Dagliyan O, Krokhotin A, Ozkan-Dagliyan I, Deiters A, Der CJ, Hahn KM, Dokholyan NV. Computational design of chemogenetic and optogenetic split proteins. Nature Communications. 9: 4042. PMID 30279442 DOI: 10.1038/s41467-018-06531-4  1
2018 Ma X, Dagliyan O, Hahn KM, Danuser G. Profiling cellular morphodynamics by spatiotemporal spectrum decomposition. Plos Computational Biology. 14: e1006321. PMID 30071020 DOI: 10.1371/journal.pcbi.1006321  1
2017 Dagliyan O, Karginov AV, Yagishita S, Gale ME, Wang H, DerMardirossian C, Wells CM, Dokholyan NV, Kasai H, Hahn KM. Engineering Pak1 allosteric switches. Acs Synthetic Biology. PMID 28365983 DOI: 10.1021/acssynbio.6b00359  1
2016 Dagliyan O, Tarnawski M, Chu PH, Shirvanyants D, Schlichting I, Dokholyan NV, Hahn KM. Engineering extrinsic disorder to control protein activity in living cells. Science (New York, N.Y.). 354: 1441-1444. PMID 27980211 DOI: 10.1126/science.aah3404  1
2016 Hodgson L, Spiering D, Sabouri-Ghomi M, Dagliyan O, DerMardirossian C, Danuser G, Hahn KM. FRET binding antenna reports spatiotemporal dynamics of GDI-Cdc42 GTPase interactions. Nature Chemical Biology. PMID 27501396 DOI: 10.1038/nchembio.2145  1
2015 Shobair M, Dagliyan O, Kota P, Dang YL, He H, Stutts MJ, Dokholyan NV. Gain-of-function mutation W493R in the epithelial sodium channel allosterically reconfigures intersubunit coupling. The Journal of Biological Chemistry. PMID 26668308 DOI: 10.1074/jbc.M115.678052  1
2014 Chu PH, Tsygankov D, Berginski ME, Dagliyan O, Gomez SM, Elston TC, Karginov AV, Hahn KM. Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms. Proceedings of the National Academy of Sciences of the United States of America. 111: 12420-5. PMID 25118278 DOI: 10.1073/pnas.1404487111  1
2014 Furukawa Y, Teraguchi S, Ikegami T, Dagliyan O, Jin L, Hall D, Dokholyan NV, Namba K, Akira S, Kurosaki T, Baba Y, Standley DM. Intrinsic disorder mediates cooperative signal transduction in STIM1. Journal of Molecular Biology. 426: 2082-97. PMID 24650897 DOI: 10.1016/j.jmb.2014.03.006  1
2014 Redler RL, Shirvanyants D, Dagliyan O, Ding F, Kim DN, Kota P, Proctor EA, Ramachandran S, Tandon A, Dokholyan NV. Computational approaches to understanding protein aggregation in neurodegeneration. Journal of Molecular Cell Biology. 6: 104-15. PMID 24620031 DOI: 10.1093/jmcb/mju007  1
2013 Freeman TC, Black JL, Bray HG, Dagliyan O, Wu YI, Tripathy A, Dokholyan NV, Leisner TM, Parise LV. Identification of novel integrin binding partners for calcium and integrin binding protein 1 (CIB1): structural and thermodynamic basis of CIB1 promiscuity. Biochemistry. 52: 7082-90. PMID 24011356 DOI: 10.1021/bi400678y  1
2013 Kummer L, Hsu CW, Dagliyan O, MacNevin C, Kaufholz M, Zimmermann B, Dokholyan NV, Hahn KM, Plückthun A. Knowledge-based design of a biosensor to quantify localized ERK activation in living cells. Chemistry & Biology. 20: 847-56. PMID 23790495 DOI: 10.1016/j.chembiol.2013.04.016  1
2013 Dagliyan O, Shirvanyants D, Karginov AV, Ding F, Fee L, Chandrasekaran SN, Freisinger CM, Smolen GA, Huttenlocher A, Hahn KM, Dokholyan NV. Rational design of a ligand-controlled protein conformational switch. Proceedings of the National Academy of Sciences of the United States of America. 110: 6800-4. PMID 23569285 DOI: 10.1073/pnas.1218319110  1
2012 Çakir B, Dağliyan O, Dağyildiz E, Bariş İ, Kavakli IH, Kizilel S, Türkay M. Structure based discovery of small molecules to regulate the activity of human insulin degrading enzyme. Plos One. 7: e31787. PMID 22355395 DOI: 10.1371/journal.pone.0031787  1
2011 Dagliyan O, Proctor EA, D'Auria KM, Ding F, Dokholyan NV. Structural and dynamic determinants of protein-peptide recognition. Structure (London, England : 1993). 19: 1837-45. PMID 22153506 DOI: 10.1016/j.str.2011.09.014  1
Low-probability matches
2020 Pablo M, Liu B, Stone O, Dagliyan O, Elston TC, Hahn KM. Binder/Tag: A Versatile Approach to Probe and Control the Conformational Changes of Individual Molecules in Living Cells Biophysical Journal. 118: 167a. DOI: 10.1016/j.bpj.2019.11.1025  0.01
2019 Dokholyan NV, Dagliyan O, Hahn KM. Control of Cellular Networks by Structural Disorder Biophysical Journal. 116: 490a. DOI: 10.1016/j.bpj.2018.11.2645  0.01
2018 Liu B, Stone O, Dagliyan O, Hahn K. Probe the Conformational Changes of Individual Molecules in Living Cells Biophysical Journal. 114: 21a. DOI: 10.1016/j.bpj.2017.11.158  0.01
2017 Kaul N, Wang H, Dagliyan O, Hahn KM. An Optogenetic Approach to Control Microtubule Acetylation in Living Cells Biophysical Journal. 112: 563a. DOI: 10.1016/j.bpj.2016.11.3034  0.01
2017 Ma X, Dagliyan O, Hahn K, Danuser G. Morphodynamic Profiling of Cell Protrusion Based on Spatiotemporal Spectrum Decomposition and Unsupervised Clustering Biophysical Journal. 112: 45a. DOI: 10.1016/j.bpj.2016.11.285  0.01
2011 Dagliyan O, Uney-Yuksektepe F, Kavakli IH, Turkay M. Optimization based tumor classification from microarray gene expression data. Plos One. 6: e14579. PMID 21326602 DOI: 10.1371/journal.pone.0014579  0.01
2011 Turkay M, Cakir B, Dagliyan O, Kavakli IH, Kizilel S. Structure based discovery of small molecules to regulate the activity of insulin degrading enzyme Current Opinion in Biotechnology. 22: S41. DOI: 10.1016/j.copbio.2011.05.101  0.01
2009 Dagliyan O, Kavakli IH, Turkay M. Classification of cytochrome P450 inhibitors with respect to binding free energy and pIC50 using common molecular descriptors. Journal of Chemical Information and Modeling. 49: 2403-11. PMID 19777996 DOI: 10.1021/ci900247t  0.01
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