| Year |
Citation |
Score |
| 2024 |
Sikora J, Dovero S, Kinet R, Arotcarena ML, Bohic S, Bezard E, Fernagut PO, Dehay B. Nigral ATP13A2 depletion induces Parkinson's disease-related neurodegeneration in a pilot study in non-human primates. Npj Parkinson's Disease. 10: 141. PMID 39090150 DOI: 10.1038/s41531-024-00757-4 |
0.634 |
|
| 2024 |
Bezard E, Teil M, Arotcarena ML, Porras G, Li Q, Dehay B. Corrigendum: Modeling Parkinson's Disease in Primates. Cold Spring Harbor Perspectives in Medicine. PMID 39054071 DOI: 10.1101/cshperspect.a041802 |
0.56 |
|
| 2024 |
Bezard E, Teil M, Arotcarena ML, Porras G, Li Q, Dehay B. Modeling Parkinson's Disease in Primates. Cold Spring Harbor Perspectives in Medicine. PMID 38858083 DOI: 10.1101/cshperspect.a041612 |
0.64 |
|
| 2023 |
Darricau M, Dou C, Kinet R, Zhu T, Zhou L, Li X, Bedel A, Claverol S, Tokarski C, Katsinelos T, McEwan WA, Zhang L, Gao R, Bourdenx M, Dehay B, et al. Tau seeds from Alzheimer's disease brains trigger tau spread in macaques while oligomeric-Aβ mediates pathology maturation. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38148705 DOI: 10.1002/alz.13604 |
0.79 |
|
| 2023 |
Teil M, Dovero S, Bourdenx M, Arotcarena ML, Darricau M, Porras G, Thiolat ML, Trigo-Damas I, Perier C, Estrada C, Garcia-Carrillo N, Herrero MT, Vila M, Obeso JA, Bezard E, ... Dehay B, et al. Cortical Lewy body injections induce long-distance pathogenic alterations in the non-human primate brain. Npj Parkinson's Disease. 9: 135. PMID 37726343 DOI: 10.1038/s41531-023-00579-w |
0.831 |
|
| 2023 |
Kinet R, Dehay B. Pathogenic Aspects and Therapeutic Avenues of Autophagy in Parkinson's Disease. Cells. 12. PMID 36831288 DOI: 10.3390/cells12040621 |
0.383 |
|
| 2022 |
Darricau M, Katsinelos T, Raschella F, Milekovic T, Crochemore L, Li Q, Courtine G, McEwan WA, Dehay B, Bezard E, Planche V. Tau seeds from patients induce progressive supranuclear palsy pathology and symptoms in primates. Brain : a Journal of Neurology. PMID 36382344 DOI: 10.1093/brain/awac428 |
0.549 |
|
| 2022 |
Teil M, Doudnikoff E, Thiolat ML, Bohic S, Bezard E, Dehay B. The Zinc Ionophore Clioquinol Reduces Parkinson's Disease Patient-Derived Brain Extracts-Induced Neurodegeneration. Molecular Neurobiology. PMID 35915387 DOI: 10.1007/s12035-022-02974-5 |
0.615 |
|
| 2022 |
Arotcarena ML, Soria FN, Cunha A, Doudnikoff E, Prévot G, Daniel J, Blanchard-Desce M, Barthélémy P, Bezard E, Crauste-Manciet S, Dehay B. Acidic nanoparticles protect against α-synuclein-induced neurodegeneration through the restoration of lysosomal function. Aging Cell. 21: e13584. PMID 35318803 DOI: 10.1111/acel.13584 |
0.652 |
|
| 2022 |
Teil M, Dovero S, Bourdenx M, Arotcarena ML, Camus S, Porras G, Thiolat ML, Trigo-Damas I, Perier C, Estrada C, Garcia-Carrillo N, Morari M, Meissner WG, Herrero MT, Vila M, ... ... Dehay B, et al. Brain injections of glial cytoplasmic inclusions induce a multiple system atrophy-like pathology. Brain : a Journal of Neurology. PMID 35285474 DOI: 10.1093/brain/awab374 |
0.841 |
|
| 2022 |
Bezard E, Dehay B. [Aggregation and spread of synuclein in Parkinson's disease]. Medecine Sciences : M/S. 38: 45-51. PMID 35060886 DOI: 10.1051/medsci/2021241 |
0.617 |
|
| 2021 |
Blesa J, Foffani G, Dehay B, Bezard E, Obeso JA. Motor and non-motor circuit disturbances in early Parkinson disease: which happens first? Nature Reviews. Neuroscience. PMID 34907352 DOI: 10.1038/s41583-021-00542-9 |
0.581 |
|
| 2021 |
Arotcarena ML, Dovero S, Biendon N, Dutheil N, Planche V, Bezard E, Dehay B. Pilot Study Assessing the Impact of Intrathecal Administration of Variants AAV-PHP.B and AAV-PHP.eB on Brain Transduction in Adult Rhesus Macaques. Frontiers in Bioengineering and Biotechnology. 9: 762209. PMID 34869273 DOI: 10.3389/fbioe.2021.762209 |
0.497 |
|
| 2021 |
Brouillard M, Barthélémy P, Dehay B, Crauste-Manciet S, Desvergnes V. Nucleolipid Acid-Based Nanocarriers Restore Neuronal Lysosomal Acidification Defects. Frontiers in Chemistry. 9: 736554. PMID 34490217 DOI: 10.3389/fchem.2021.736554 |
0.314 |
|
| 2021 |
Darricau M, Canron MH, Bosc M, Arotçarena ML, Quang ML, Dehay B, Bezard E, Planche V. Lack of limbic-predominant age-related TDP-43 encephalopathy (LATE) neuropathological changes in aged macaques with memory impairment. Neurobiology of Aging. 107: 53-56. PMID 34384992 DOI: 10.1016/j.neurobiolaging.2021.07.009 |
0.413 |
|
| 2021 |
Teil M, Arotcarena ML, Dehay B. A New Rise of Non-Human Primate Models of Synucleinopathies. Biomedicines. 9. PMID 33803341 DOI: 10.3390/biomedicines9030272 |
0.323 |
|
| 2021 |
Sun X, Yu X, Zhang L, Zhao W, Wang M, Zhang Y, Li X, Gao R, Breger LS, Dovero S, Porras G, Fernagut PO, Dehay B, Bezard E, Qin C. Comparison of the expression and toxicity of AAV2/9 carrying the human A53T α-synuclein gene in presence or absence of WPRE. Heliyon. 7: e06302. PMID 33665452 DOI: 10.1016/j.heliyon.2021.e06302 |
0.562 |
|
| 2021 |
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Dehay B, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280 |
0.76 |
|
| 2021 |
Feyder M, Plewnia C, Lieberman OJ, Spigolon G, Piccin A, Urbina L, Dehay B, Li Q, Nilsson P, Altun M, Santini E, Sulzer D, Bezard E, Borgkvist A, Fisone G. Involvement of Autophagy in Levodopa-Induced Dyskinesia. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 33460487 DOI: 10.1002/mds.28480 |
0.501 |
|
| 2021 |
Yu X, Persillet M, Zhang L, Zhang Y, Xiuping S, Li X, Ran G, Breger LS, Dovero S, Porras G, Dehay B, Bezard E, Qin C. Evaluation of blood flow as a route for propagation in experimental synucleinopathy. Neurobiology of Disease. 105255. PMID 33421564 DOI: 10.1016/j.nbd.2021.105255 |
0.58 |
|
| 2020 |
Deffains M, Canron MH, Teil M, Li Q, Dehay B, Bezard E, Fernagut PO. L-DOPA regulates α-synuclein accumulation in experimental parkinsonism. Neuropathology and Applied Neurobiology. PMID 33275784 DOI: 10.1111/nan.12678 |
0.612 |
|
| 2020 |
Bengoa-Vergniory N, Faggiani E, Ramos-Gonzalez P, Kirkiz E, Connor-Robson N, Brown LV, Siddique I, Li Z, Vingill S, Cioroch M, Cavaliere F, Threlfell S, Roberts B, Schrader T, Klärner FG, ... ... Dehay B, et al. CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson's disease. Nature Communications. 11: 4885. PMID 32985503 DOI: 10.1038/s41467-020-18689-x |
0.588 |
|
| 2020 |
Soria FN, Paviolo C, Doudnikoff E, Arotcarena ML, Lee A, Danné N, Mandal AK, Gosset P, Dehay B, Groc L, Cognet L, Bezard E. Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling. Nature Communications. 11: 3440. PMID 32651387 DOI: 10.1038/S41467-020-17328-9 |
0.581 |
|
| 2020 |
Maxan A, Sciacca G, Alpaugh M, Tao Z, Breger L, Dehay B, Ling Z, Qin C, Cisbani G, Masnata M, Salem S, Lacroix S, Oueslati A, Bezard E, Cicchetti F. Use of adeno-associated virus-mediated delivery of mutant huntingtin to study the spreading capacity of the protein in mice and non-human primates. Neurobiology of Disease. 104951. PMID 32439599 DOI: 10.1016/J.Nbd.2020.104951 |
0.537 |
|
| 2020 |
Yu Z, Shi M, Stewart T, Fernagut PO, Huang Y, Tian C, Dehay B, Atik A, Yang D, De Giorgi F, Ichas F, Canron MH, Ceravolo R, Frosini D, Kim HJ, et al. Reduced oligodendrocyte exosome secretion in multiple system atrophy involves SNARE dysfunction. Brain : a Journal of Neurology. PMID 32428221 DOI: 10.1093/Brain/Awaa110 |
0.521 |
|
| 2020 |
Bourdenx M, Nioche A, Dovero S, Arotcarena ML, Camus S, Porras G, Thiolat ML, Rougier NP, Prigent A, Aubert P, Bohic S, Sandt C, Laferrière F, Doudnikoff E, Kruse N, ... ... Dehay B, et al. Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates. Science Advances. 6: eaaz9165. PMID 32426502 DOI: 10.1126/Sciadv.Aaz9165 |
0.838 |
|
| 2020 |
Gosset P, Maxan A, Alpaugh M, Breger L, Dehay B, Tao Z, Ling Z, Qin C, Cisbani G, Fortin N, Vonsattel JG, Lacroix S, Oueslati A, Bezard E, Cicchetti F. Evidence for the spread of human-derived mutant huntingtin protein in mice and non-human primates. Neurobiology of Disease. 104941. PMID 32422281 DOI: 10.1016/J.Nbd.2020.104941 |
0.597 |
|
| 2020 |
Arotcarena ML, Dovero S, Prigent A, Bourdenx M, Camus S, Porras G, Thiolat ML, Tasselli M, Aubert P, Kruse N, Mollenhauer B, Damas IT, Estrada C, Garcia-Carrillo N, Vaikath NN, ... ... Dehay B, et al. Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates. Brain : a Journal of Neurology. PMID 32380543 DOI: 10.1093/Brain/Awaa096 |
0.831 |
|
| 2020 |
Lopez-Cuina M, Guerin PA, Canron MH, Delamarre A, Dehay B, Bezard E, Meissner WG, Fernagut PO. Nilotinib Fails to Prevent Synucleinopathy and Cell Loss in a Mouse Model of Multiple System Atrophy. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 32291831 DOI: 10.1002/Mds.28034 |
0.641 |
|
| 2020 |
Teil M, Arotcarena ML, Faggiani E, Laferriere F, Bezard E, Dehay B. Targeting α-synuclein for PD Therapeutics: A Pursuit on All Fronts. Biomolecules. 10. PMID 32138193 DOI: 10.3390/biom10030391 |
0.629 |
|
| 2019 |
Meissner WG, Fernagut PO, Dehay B, Péran P, Traon AP, Foubert-Samier A, Lopez Cuina M, Bezard E, Tison F, Rascol O. Multiple System Atrophy: Recent Developments and Future Perspectives. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 31692132 DOI: 10.1002/Mds.27894 |
0.624 |
|
| 2019 |
Dehay B, Bezard E. Intrastriatal injection of alpha-synuclein fibrils induces Parkinson-like pathology in macaques. Brain : a Journal of Neurology. 142: 3321-3322. PMID 31665750 DOI: 10.1093/Brain/Awz329 |
0.557 |
|
| 2019 |
Arotcarena ML, Bourdenx M, Dutheil N, Thiolat ML, Doudnikoff E, Dovero S, Ballabio A, Fernagut PO, Meissner WG, Bezard E, Dehay B. Transcription factor EB overexpression prevents neurodegeneration in experimental synucleinopathies. Jci Insight. 4. PMID 31434803 DOI: 10.1172/Jci.Insight.129719 |
0.835 |
|
| 2019 |
Arotcarena ML, Teil M, Dehay B. Autophagy in Synucleinopathy: The Overwhelmed and Defective Machinery. Cells. 8. PMID 31181865 DOI: 10.3390/Cells8060565 |
0.424 |
|
| 2018 |
Bonsi P, Ponterio G, Vanni V, Tassone A, Sciamanna G, Migliarini S, Martella G, Meringolo M, Dehay B, Doudnikoff E, Zachariou V, Goodchild RE, Mercuri NB, D'Amelio M, Pasqualetti M, et al. RGS9-2 rescues dopamine D2 receptor levels and signaling in dystonia mouse models. Embo Molecular Medicine. PMID 30552094 DOI: 10.15252/Emmm.201809283 |
0.509 |
|
| 2018 |
Prevot G, Soria FN, Thiolat ML, Daniel J, Verlhac JB, Blanchard-Desce M, Bezard E, Barthelemy P, Crauste-Manciet S, Dehay B. Harnessing Lysosomal pH through PLGA Nanoemulsion as a Treatment of Lysosomal-related Neurodegenerative Diseases. Bioconjugate Chemistry. PMID 30424597 DOI: 10.1021/Acs.Bioconjchem.8B00697 |
0.609 |
|
| 2018 |
Chansel-Debordeaux L, Bourdenx M, Dutheil N, Dovero S, Canron MH, Jimenez C, Bezard E, Dehay B. Systemic gene delivery by single-dose intracardiac administration of scAAV2/9 and scAAV2/rh10 variants in newborn rats. Human Gene Therapy Methods. PMID 30064266 DOI: 10.1089/Hgtb.2017.192.R3 |
0.779 |
|
| 2017 |
Perez-Villalba A, Salomé Sirerol-Piquer M, Belenguer G, Soriano-Cantón R, Belén Muñoz-Manchado A, Villadiego J, Alarcón-Arís D, Soria FN, Dehay B, Bezard E, Vila M, Bortolozzi A, José Toledo-Aral J, Pérez-Sánchez F, Fariñas I. Synaptic regulator α-synuclein in dopaminergic fibers is essentially required for the maintenance of subependymal neural stem cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29217686 DOI: 10.1523/Jneurosci.2276-17.2017 |
0.62 |
|
| 2017 |
Recasens A, Ulusoy A, Kahle PJ, Di Monte DA, Dehay B. In vivo models of alpha-synuclein transmission and propagation. Cell and Tissue Research. PMID 29185072 DOI: 10.1007/S00441-017-2730-9 |
0.509 |
|
| 2017 |
Chansel-Debordeaux L, Bourdenx M, Dovero S, Grouthier V, Dutheil N, Espana A, Groc L, Jimenez C, Bezard E, Dehay B. In utero delivery of rAAV2/9 induces neuronal expression of the transgene in the brain: towards new models of Parkinson's disease. Gene Therapy. 24: 801-809. PMID 28853717 DOI: 10.1038/Gt.2017.84 |
0.816 |
|
| 2017 |
Soria FN, Engeln M, Martinez-Vicente M, Glangetas C, López-González MJ, Dovero S, Dehay B, Normand E, Vila M, Favereaux A, Georges F, Lo Bianco C, Bezard E, Fernagut PO. Glucocerebrosidase deficiency in dopaminergic neurons induces microglial activation without neurodegeneration. Human Molecular Genetics. PMID 28520872 DOI: 10.1093/Hmg/Ddx120 |
0.606 |
|
| 2017 |
Cavaliere F, Cerf L, Dehay B, Ramos-Gonzalez P, De Giorgi F, Bourdenx M, Bessede A, Obeso JA, Matute C, Ichas F, Bezard E. In vitro α-synuclein neurotoxicity and spreading among neurons and astrocytes using Lewy body extracts from Parkinson disease brains. Neurobiology of Disease. 103: 101-112. PMID 28411117 DOI: 10.1016/J.Nbd.2017.04.011 |
0.816 |
|
| 2017 |
Schmitt M, Dehay B, Bezard E, Garcia-Ladona FJ. U18666A, an Activator of Sterol Regulatory Element Binding Protein (SREBP) Pathway Modulates Presynaptic Dopaminergic Phenotype of SH-SY5Y Neuroblastoma Cells. Synapse (New York, N.Y.). PMID 28407359 DOI: 10.1002/Syn.21980 |
0.624 |
|
| 2017 |
Bourdenx M, Dovero S, Thiolat ML, Bezard E, Dehay B. Lack of spontaneous age-related brain pathology in Octodon degus: a reappraisal of the model. Scientific Reports. 7: 45831. PMID 28374864 DOI: 10.1038/Srep45831 |
0.82 |
|
| 2017 |
Bourdenx M, Dehay B. [Autophagy and brain: the case of neurodegenerative diseases]. Medecine Sciences : M/S. 33: 268-274. PMID 28367813 DOI: 10.1051/Medsci/20173303013 |
0.807 |
|
| 2017 |
Soria FN, Pampliega O, Bourdenx M, Meissner WG, Bezard E, Dehay B. Exosomes, an Unmasked Culprit in Neurodegenerative Diseases. Frontiers in Neuroscience. 11: 26. PMID 28197068 DOI: 10.3389/Fnins.2017.00026 |
0.802 |
|
| 2017 |
Ysselstein D, Dehay B, Costantino IM, McCabe GP, Frosch MP, George JM, Bezard E, Rochet JC. Endosulfine-alpha inhibits membrane-induced α-synuclein aggregation and protects against α-synuclein neurotoxicity. Acta Neuropathologica Communications. 5: 3. PMID 28069058 DOI: 10.1186/S40478-016-0403-7 |
0.583 |
|
| 2016 |
Dehay B, Fernagut PO. Alpha-synuclein-based models of Parkinson's disease. Revue Neurologique. 172: 371-8. PMID 27158042 DOI: 10.1016/J.Neurol.2016.04.003 |
0.566 |
|
| 2016 |
Bourdenx M, Dehay B. What lysosomes actually tell us about Parkinson's disease? Ageing Research Reviews. 32: 140-149. PMID 26947123 DOI: 10.1016/J.Arr.2016.02.008 |
0.839 |
|
| 2016 |
Dehay B, Decressac M, Bourdenx M, Guadagnino I, Fernagut PO, Tamburrino A, Bassil F, Meissner WG, Bezard E. Targeting α-synuclein: Therapeutic options. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 26926119 DOI: 10.1002/Mds.26568 |
0.828 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Dehay B, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886 |
0.475 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Dehay B, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356 |
0.526 |
|
| 2016 |
Bourdenx M, Daniel J, Genin E, Soria FN, Blanchard-Desce M, Bezard E, Dehay B. Nanoparticles restore lysosomal acidification defects: Implication for Parkinson and other lysosomal-related diseases. Autophagy. 0. PMID 26761717 DOI: 10.1080/15548627.2015.1136769 |
0.823 |
|
| 2016 |
Sauvestre F, Dehay B, Bézard E, Martin-Négrier M. Étude des anomalies morphologiques mitochondriales dans des lignées cellulaires humaines mutées pour le gène parkin Morphologie. 100: 170-171. DOI: 10.1016/J.Morpho.2016.07.023 |
0.452 |
|
| 2015 |
Bourdenx M, Dehay B, Bezard' E. Experimental modelling of -synuclein aggregation and spreading in synucleinopathies. Bulletin De L'Academie Nationale De Medecine. 199: 797-808. PMID 29901880 |
0.825 |
|
| 2015 |
Schmitt M, Dehay B, Bezard E, Garcia-Ladona FJ. Harnessing the Trophic and Modulatory Potential of Statins in a Dopaminergic Cell Line. Synapse (New York, N.Y.). PMID 26695835 DOI: 10.1002/Syn.21881 |
0.6 |
|
| 2015 |
Dehay B, Vila M, Bezard E, Brundin P, Kordower JH. Alpha-synuclein propagation: New insights from animal models. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 26347034 DOI: 10.1002/Mds.26370 |
0.573 |
|
| 2015 |
Bourdenx M, Koulakiotis NS, Sanoudou D, Bezard E, Dehay B, Tsarbopoulos A. Protein aggregation and neurodegeneration in prototypical neurodegenerative diseases: Examples of amyloidopathies, tauopathies and synucleinopathies. Progress in Neurobiology. PMID 26209472 DOI: 10.1016/J.Pneurobio.2015.07.003 |
0.83 |
|
| 2015 |
Bourdenx M, Dovero S, Engeln M, Bido S, Bastide MF, Dutheil N, Vollenweider I, Baud L, Piron C, Grouthier V, Boraud T, Porras G, Li Q, Baekelandt V, Scheller D, ... ... Dehay B, et al. Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression. Acta Neuropathologica Communications. 3: 46. PMID 26205255 DOI: 10.1186/S40478-015-0222-2 |
0.826 |
|
| 2015 |
Dehay B, Bourdenx M, Gorry P, Przedborski S, Vila M, Hunot S, Singleton A, Olanow CW, Merchant KM, Bezard E, Petsko GA, Meissner WG. Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations. The Lancet. Neurology. PMID 26050140 DOI: 10.1016/S1474-4422(15)00006-X |
0.833 |
|
| 2015 |
Bourdenx M, Dehay B, Bezard E. Modélisation expérimentale de l’agrégation et de la propagation de l’α-synucléine dans les synucléinopathies Bulletin De L'AcadéMie Nationale De MéDecine. 199: 797-808. DOI: 10.1016/S0001-4079(19)30882-9 |
0.746 |
|
| 2014 |
Recasens A, Dehay B. Alpha-synuclein spreading in Parkinson's disease. Frontiers in Neuroanatomy. 8: 159. PMID 25565982 DOI: 10.3389/Fnana.2014.00159 |
0.548 |
|
| 2014 |
Bourdenx M, Dehay B, Bezard E. Down-regulating α-synuclein for treating synucleopathies. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 1463-5. PMID 25214445 DOI: 10.1002/Mds.26028 |
0.784 |
|
| 2014 |
Bourdenx M, Bezard E, Dehay B. Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death. Frontiers in Neuroanatomy. 8: 83. PMID 25177278 DOI: 10.3389/Fnana.2014.00083 |
0.842 |
|
| 2014 |
Engeln M, Bastide MF, Toulmé E, Dehay B, Bourdenx M, Doudnikoff E, Li Q, Gross CE, Boué-Grabot E, Pisani A, Bezard E, Fernagut PO. Selective Inactivation of Striatal FosB/ΔFosB-Expressing Neurons Alleviates L-Dopa-Induced Dyskinesia. Biological Psychiatry. PMID 25146322 DOI: 10.1016/J.Biopsych.2014.07.007 |
0.782 |
|
| 2014 |
Bourdenx M, Dutheil N, Bezard E, Dehay B. Systemic gene delivery to the central nervous system using Adeno-associated virus. Frontiers in Molecular Neuroscience. 7: 50. PMID 24917785 DOI: 10.3389/Fnmol.2014.00050 |
0.784 |
|
| 2014 |
Fernagut PO, Dehay B, Maillard A, Bezard E, Perez P, Pavy-Le Traon A, Rascol O, Foubert-Samier A, Tison F, Meissner WG. Multiple system atrophy: a prototypical synucleinopathy for disease-modifying therapeutic strategies. Neurobiology of Disease. 67: 133-9. PMID 24727096 DOI: 10.1016/J.Nbd.2014.03.021 |
0.621 |
|
| 2014 |
Bové J, Martínez-Vicente M, Dehay B, Perier C, Recasens A, Bombrun A, Antonsson B, Vila M. BAX channel activity mediates lysosomal disruption linked to Parkinson disease. Autophagy. 10: 889-900. PMID 24686337 DOI: 10.4161/Auto.28286 |
0.48 |
|
| 2014 |
Recasens A, Dehay B, Bové J, Carballo-Carbajal I, Dovero S, Pérez-Villalba A, Fernagut PO, Blesa J, Parent A, Perier C, Fariñas I, Obeso JA, Bezard E, Vila M. Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys. Annals of Neurology. 75: 351-62. PMID 24243558 DOI: 10.1002/Ana.24066 |
0.673 |
|
| 2014 |
Porras G, Dehay B, Bezard E. Viral vectors in primate research: Examples from Parkinson’s disease research Neuromethods. 82: 331-341. DOI: 10.1007/978-1-62703-610-8_17 |
0.437 |
|
| 2013 |
Dehay B, Martinez-Vicente M, Caldwell GA, Caldwell KA, Yue Z, Cookson MR, Klein C, Vila M, Bezard E. Lysosomal impairment in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 725-32. PMID 23580333 DOI: 10.1002/Mds.25462 |
0.642 |
|
| 2012 |
Canron MH, Perret M, Vital A, Bézard E, Dehay B. Age-dependent α-synuclein aggregation in the Microcebus murinus lemur primate. Scientific Reports. 2: 910. PMID 23205271 DOI: 10.1038/Srep00910 |
0.393 |
|
| 2012 |
Porras G, Berthet A, Dehay B, Li Q, Ladepeche L, Normand E, Dovero S, Martinez A, Doudnikoff E, Martin-Négrier ML, Chuan Q, Bloch B, Choquet D, Boué-Grabot E, Groc L, et al. PSD-95 expression controls L-DOPA dyskinesia through dopamine D1 receptor trafficking. The Journal of Clinical Investigation. 122: 3977-89. PMID 23041629 DOI: 10.1172/Jci59426 |
0.541 |
|
| 2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Dehay B, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.628 |
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| 2012 |
Dehay B, Martinez-Vicente M, Ramirez A, Perier C, Klein C, Vila M, Bezard E. Lysosomal dysfunction in Parkinson disease: ATP13A2 gets into the groove. Autophagy. 8: 1389-91. PMID 22885599 DOI: 10.4161/Auto.21011 |
0.641 |
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| 2012 |
Ramonet D, Perier C, Recasens A, Dehay B, Bové J, Costa V, Scorrano L, Vila M. Optic atrophy 1 mediates mitochondria remodeling and dopaminergic neurodegeneration linked to complex I deficiency. Cell Death and Differentiation. 20: 77-85. PMID 22858546 DOI: 10.1038/Cdd.2012.95 |
0.349 |
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| 2012 |
Dehay B, Ramirez A, Martinez-Vicente M, Perier C, Canron MH, Doudnikoff E, Vital A, Vila M, Klein C, Bezard E. Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 109: 9611-6. PMID 22647602 DOI: 10.1073/Pnas.1112368109 |
0.649 |
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| 2012 |
Dehay B. New experimental approach for modeling Parkinson’s disease. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 344. PMID 22512004 DOI: 10.1002/Mds.24933 |
0.331 |
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| 2012 |
Dehay B, Dalkara D, Dovero S, Li Q, Bezard E. Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques. Scientific Reports. 2: 253. PMID 22355765 DOI: 10.1038/Srep00253 |
0.573 |
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| 2012 |
Berthet A, Bezard E, Porras G, Fasano S, Barroso-Chinea P, Dehay B, Martinez A, Thiolat ML, Nosten-Bertrand M, Giros B, Baufreton J, Li Q, Bloch B, Martin-Negrier ML. L-DOPA impairs proteasome activity in parkinsonism through D1 dopamine receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 681-91. PMID 22238104 DOI: 10.1523/Jneurosci.1541-11.2012 |
0.596 |
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| 2012 |
Sánchez-Danés A, Consiglio A, Richaud Y, Rodríguez-Pizà I, Dehay B, Edel M, Bové J, Memo M, Vila M, Raya A, Izpisua Belmonte JC. Efficient generation of A9 midbrain dopaminergic neurons by lentiviral delivery of LMX1A in human embryonic stem cells and induced pluripotent stem cells Human Gene Therapy. 23: 56-69. PMID 21877920 DOI: 10.1089/Hum.2011.054 |
0.405 |
|
| 2011 |
Dehay B. The true nature of α-synuclein unmasked! Movement Disorders : Official Journal of the Movement Disorder Society. 26: 2324. PMID 22319787 DOI: 10.1002/Mds.24009 |
0.375 |
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| 2011 |
Dehay B, Bezard E. New animal models of Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 1198-1205. PMID 22046592 DOI: 10.1002/Mds.23546 |
0.656 |
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| 2011 |
Dehay B. α-synuclein, a prion-like protein. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 774. PMID 21671511 DOI: 10.1002/Mds.23748 |
0.392 |
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| 2011 |
Vila M, Bové J, Dehay B, Rodríguez-Muela N, Boya P. Lysosomal membrane permeabilization in Parkinson disease. Autophagy. 7: 98-100. PMID 21045565 DOI: 10.4161/Auto.7.1.13933 |
0.494 |
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| 2010 |
Dehay B, Bové J, Rodríguez-Muela N, Perier C, Recasens A, Boya P, Vila M. Pathogenic lysosomal depletion in Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 12535-44. PMID 20844148 DOI: 10.1523/Jneurosci.1920-10.2010 |
0.496 |
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| 2010 |
Perier C, Bové J, Dehay B, Jackson-Lewis V, Rabinovitch PS, Przedborski S, Vila M. Apoptosis-inducing factor deficiency sensitizes dopaminergic neurons to parkinsonian neurotoxins. Annals of Neurology. 68: 184-92. PMID 20695011 DOI: 10.1002/Ana.22034 |
0.645 |
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| 2007 |
Perier C, Bové J, Wu DC, Dehay B, Choi DK, Jackson-Lewis V, Rathke-Hartlieb S, Bouillet P, Strasser A, Schulz JB, Przedborski S, Vila M. Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 104: 8161-6. PMID 17483459 DOI: 10.1073/Pnas.0609874104 |
0.621 |
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| 2007 |
Dehay B, Weber C, Trottier Y, Bertolotti A. Mapping of the epitope of monoclonal antibody 2B4 to the proline-rich region of human Huntingtin, a region critical for aggregation and toxicity. Biotechnology Journal. 2: 559-64. PMID 17373643 DOI: 10.1002/Biot.200600249 |
0.356 |
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| 2006 |
Dehay B, Bertolotti A. Critical role of the proline-rich region in Huntingtin for aggregation and cytotoxicity in yeast. The Journal of Biological Chemistry. 281: 35608-15. PMID 16973603 DOI: 10.1074/Jbc.M605558200 |
0.343 |
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| 2004 |
Rousseau E, Dehay B, Ben-Haïem L, Trottier Y, Morange M, Bertolotti A. Targeting expression of expanded polyglutamine proteins to the endoplasmic reticulum or mitochondria prevents their aggregation. Proceedings of the National Academy of Sciences of the United States of America. 101: 9648-53. PMID 15210964 DOI: 10.1073/Pnas.0403015101 |
0.365 |
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