Giles S. H. Yeo, PhD - Publications

Affiliations: 
Institute of Metabolic Science University of Cambridge, Cambridge, England, United Kingdom 
Area:
Metabolism, Genetics, Genomics

139 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Saucisse N, Mazier W, Simon V, Binder E, Catania C, Bellocchio L, Romanov RA, Léon S, Matias I, Zizzari P, Quarta C, Cannich A, Meece K, Gonzales D, Clark S, ... ... Yeo GSH, et al. Functional heterogeneity of POMC neurons relies on mTORC1 signaling. Cell Reports. 37: 109800. PMID 34644574 DOI: 10.1016/j.celrep.2021.109800  1
2021 Cimino I, Rimmington D, Tung YCL, Lawler K, Larraufie P, Kay RG, Virtue S, Lam BYH, Fagnocchi L, Ma MKL, Saudek V, Zvetkova I, Vidal-Puig A, Yeo GSH, Farooqi IS, et al. Murine neuronatin deficiency is associated with a hypervariable food intake and bimodal obesity. Scientific Reports. 11: 17571. PMID 34475432 DOI: 10.1038/s41598-021-96278-8  1
2021 Gupta D, Dowsett GKC, Mani BK, Shankar K, Osborne-Lawrence S, Metzger NP, Lam BYH, Yeo GSH, Zigman JM. High co-expression of the ghrelin and LEAP2 receptor GHSR with pancreatic polypeptide in mouse and human islets. Endocrinology. PMID 34289060 DOI: 10.1210/endocr/bqab148  1
2021 Yeo GSH, O'Rahilly S. Finding genes that control body weight. Science (New York, N.Y.). 373: 30-31. PMID 34210869 DOI: 10.1126/science.abh3556  1
2021 Cimino I, Kim H, Tung YCL, Pedersen K, Rimmington D, Tadross JA, Kohnke SN, Neves-Costa A, Barros A, Joaquim S, Bennett D, Melvin A, Lockhart SM, Rostron AJ, Scott J, ... ... Yeo GSH, et al. Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GDF15. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34187898 DOI: 10.1073/pnas.2106868118  1
2021 Wade KH, Lam BYH, Melvin A, Pan W, Corbin LJ, Hughes DA, Rainbow K, Chen JH, Duckett K, Liu X, Mokrosiński J, Mörseburg A, Neaves S, Williamson A, Zhang C, ... ... Yeo GSH, et al. Loss-of-function mutations in the melanocortin 4 receptor in a UK birth cohort. Nature Medicine. PMID 34045736 DOI: 10.1038/s41591-021-01349-y  1
2021 Dowsett GKC, Lam BYH, Tadross JA, Cimino I, Rimmington D, Coll AP, Polex-Wolf J, Knudsen LB, Pyke C, Yeo GSH. A survey of the mouse hindbrain in the fed and fasted state using single-nucleus RNA sequencing. Molecular Metabolism. 101240. PMID 33962048 DOI: 10.1016/j.molmet.2021.101240  1
2021 Yeo GSH, Moro Chao DH, Siegert AM, Koerperich ZM, Ericson MD, Simonds SE, Larson CM, Luquet S, Clarke I, Sharma S, Clément K, Cowley MA, Haskell-Luevano C, Van Der Ploeg L, Adan RAH. The melanocortin pathway and energy homeostasis: From discovery to obesity therapy. Molecular Metabolism. 101206. PMID 33684608 DOI: 10.1016/j.molmet.2021.101206  0.01
2021 Choi RJ, Mohamad Zobir SZ, Alexander-Dann B, Sharma N, Ma MKL, Lam BYH, Yeo GSH, Zhang W, Fan TP, Bender A. Combination of Ginsenosides Rb2 and Rg3 Promotes Angiogenic Phenotype of Human Endothelial Cells via PI3K/Akt and MAPK/ERK Pathways. Frontiers in Pharmacology. 12: 618773. PMID 33643049 DOI: 10.3389/fphar.2021.618773  1
2021 Quarta C, Claret M, Zeltser LM, Williams KW, Yeo GSH, Tschöp MH, Diano S, Brüning JC, Cota D. POMC neuronal heterogeneity in energy balance and beyond: an integrated view. Nature Metabolism. PMID 33633406 DOI: 10.1038/s42255-021-00345-3  0.01
2020 Chalmers J, Tung YCL, Liu CH, O'Kane CJ, O'Rahilly S, Yeo GSH. A multi-component screen for feeding behaviour and nutritional status in Drosophila to interrogate mammalian appetite-related genes. Molecular Metabolism. 101127. PMID 33242659 DOI: 10.1016/j.molmet.2020.101127  1
2020 Roth E, Benoit S, Quentin B, Lam B, Will S, Ma M, Heeley N, Darwish T, Shrestha Y, Gribble F, Reimann F, Pshenichnaya I, Yeo G, Baker DJ, Trevaskis JL, et al. Behavioural and neurochemical mechanisms underpinning the feeding-suppressive effect of GLP-1/CCK combinatorial therapy. Molecular Metabolism. 101118. PMID 33221554 DOI: 10.1016/j.molmet.2020.101118  1
2020 Wargent ET, Martin-Gronert MS, Cripps RL, Heisler LK, Yeo GSH, Ozanne SE, Arch JRS, Stocker CJ. Developmental programming of appetite and growth in male rats increases hypothalamic serotonin (5-HT)5A receptor expression and sensitivity. International Journal of Obesity (2005). PMID 32719434 DOI: 10.1038/S41366-020-0643-2  1
2020 Ma Y, Ratnasabapathy R, De Backer I, Izzi-Engbeaya C, Nguyen-Tu MS, Cuenco J, Jones B, John CD, Lam BYH, Rutter GA, Yeo G, Dhillo W, Gardiner J. Glucose in the hypothalamic pataventricular nucleus regulates GLP-1 release. Jci Insight. PMID 32229720 DOI: 10.1172/Jci.Insight.132760  1
2020 Georgescu T, Lyons D, Doslikova B, Garcia AP, Marston O, Burke LK, Chianese R, Lam BYH, Yeo GSH, Rochford JJ, Garfield AS, Heisler LK. Neurochemical characterization of brainstem Pro-opiomelanocortin cells. Endocrinology. PMID 32166324 DOI: 10.1210/Endocr/Bqaa032  1
2020 Thackray AM, Lam B, Shahira Binti Ab Razak A, Yeo G, Bujdoso R. Transcriptional signature of prion-induced neurotoxicity in a Drosophila model of transmissible mammalian prion disease. The Biochemical Journal. 477: 833-852. PMID 32108870 DOI: 10.1042/BCJ20190872  0.01
2020 Coll AP, Chen M, Taskar P, Rimmington D, Patel S, Tadross JA, Cimino I, Yang M, Welsh P, Virtue S, Goldspink DA, Miedzybrodzka EL, Konopka AR, Esponda RR, Huang JT, ... ... Yeo GSH, et al. Publisher Correction: GDF15 mediates the effects of metformin on body weight and energy balance. Nature. PMID 32051582 DOI: 10.1038/S41586-020-2031-4  1
2019 Coll AP, Chen M, Taskar P, Rimmington D, Patel S, Tadross J, Cimino I, Yang M, Welsh P, Virtue S, Goldspink DA, Miedzybrodzka EL, Konopka AR, Esponda RR, Huang JT, ... ... Yeo GSH, et al. GDF15 mediates the effects of metformin on body weight and energy balance. Nature. PMID 31875646 DOI: 10.1038/S41586-019-1911-Y  1
2019 Clément M, Raffort J, Lareyre F, Tsiantoulas D, Newland SA, Lu Y, Masters L, Harrison J, Saveljeva S, Ma MK, Ozsvar-Kozma M, Lam B, Yeo GS, Binder CJ, Kaser A, et al. Impaired Autophagy in CD11b Dendritic Cells Expands CD4 Regulatory T Cells And Limits Atherosclerosis in Mice. Circulation Research. PMID 31610723 DOI: 10.1161/Circresaha.119.315248  1
2019 Al-Massadi O, Quiñones M, Clasadonte J, Bautista RH, Romero-Picó A, Folgueira C, Morgan DA, Kalló I, Heras V, Senra A, Funderburk SC, Krashes MJ, Souto Y, Fidalgo M, Luquet S, ... ... Yeo G, et al. MCH Regulates SIRT1/FoxO1 and Reduces POMC Neuronal Activity to Induce Hyperphagia, Adiposity and Glucose Intolerance. Diabetes. PMID 31530579 DOI: 10.2337/Db19-0029  1
2019 Adriaenssens AE, Biggs EK, Darwish T, Tadross J, Sukthankar T, Girish M, Polex-Wolf J, Lam BY, Zvetkova I, Pan W, Chiarugi D, Yeo GSH, Blouet C, Gribble FM, Reimann F. Glucose-Dependent Insulinotropic Polypeptide Receptor-Expressing Cells in the Hypothalamus Regulate Food Intake. Cell Metabolism. PMID 31447324 DOI: 10.1016/J.Cmet.2019.07.013  1
2019 Wray JR, Davies A, Sefton C, Allen TJ, Adamson A, Chapman P, Lam BYH, Yeo GSH, Coll AP, Harno E, White A. Global transcriptomic analysis of the arcuate nucleus following chronic glucocorticoid treatment. Molecular Metabolism. PMID 31176677 DOI: 10.1016/J.Molmet.2019.05.008  1
2019 Roberts GP, Larraufie P, Richards P, Kay RG, Galvin SG, Miedzybrodzka EL, Leiter A, Li HJ, Glass LL, Ma MKL, Lam B, Yeo GSH, Scharfmann R, Chiarugi D, Hardwick RH, et al. Comparison of Human and Murine Enteroendocrine Cells by Transcriptomic and Peptidomic Profiling. Diabetes. PMID 30733330 DOI: 10.2337/Db18-0883  1
2019 Larraufie P, Roberts GP, McGavigan AK, Kay RG, Li J, Leiter A, Melvin A, Biggs EK, Ravn P, Davy K, Hornigold DC, Yeo GSH, Hardwick RH, Reimann F, Gribble FM. Important Role of the GLP-1 Axis for Glucose Homeostasis after Bariatric Surgery. Cell Reports. 26: 1399-1408.e6. PMID 30726726 DOI: 10.1016/J.Celrep.2019.01.047  1
2018 Quiñones M, Al-Massadi O, Folgueira C, Bremser S, Gallego R, Torres-Leal L, Haddad-Tóvolli R, García-Caceres C, Hernandez-Bautista R, Lam BYH, Beiroa D, Sanchez-Rebordelo E, Senra A, Malagon JA, Valerio P, ... ... Yeo G, et al. p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1. Nature Communications. 9: 3432. PMID 30143607 DOI: 10.1038/S41467-018-05711-6  1
2018 Polex-Wolf J, Lam BY, Larder R, Tadross J, Rimmington D, Bosch F, Cenzano VJ, Ayuso E, Ma MK, Rainbow K, Coll AP, O'Rahilly S, Yeo GS. Hypothalamic loss of Snord116 recapitulates the hyperphagia of Prader-Willi syndrome. The Journal of Clinical Investigation. PMID 29376887 DOI: 10.1172/Jci97007  1
2018 Basatemur G, Ackers-Johnson M, Schoonejans J, Kazachenka A, Lam B, Ma M, Brimpari M, Patel M, Saleh N, Murphy D, Zhao T, Yeo G, Ferguson-Smith A, Vallier L, Sinha S, et al. 129 The CHR9P21 risk locus affects IL-1/TLR signalling in VSMC Heart. 104. DOI: 10.1136/Heartjnl-2018-Bcs.128  1
2017 Nus M, Sage AP, Lu Y, Masters L, Lam BY, Newland S, Weller S, Tsiantoulas D, Raffort J, Marcus D, Finigan A, Kitt L, Figg N, Schirmbeck R, Kneilling M, ... Yeo GS, et al. Marginal Zone B cells control follicular helper T cell response to high cholesterol diet. Atherosclerosis. 263: e12-e13. PMID 29365488 DOI: 10.1016/J.Atherosclerosis.2017.06.067  1
2017 Howard SR, Guasti L, Poliandri A, David A, Cabrera CP, Barnes MR, Wehkalampi K, O'Rahilly S, Aiken CE, Coll AP, Ma M, Rimmington D, Yeo GSH, Dunkel L. Contributions of function-altering variants in genes implicated in pubertal timing and body mass for self-limited delayed puberty. The Journal of Clinical Endocrinology and Metabolism. PMID 29161441 DOI: 10.1210/Jc.2017-02147  1
2017 Cimino I, Coll AP, Yeo GSH. GDF15 and energy balance: homing in on a mechanism. Nature Medicine. 23: 1119-1120. PMID 28985212 DOI: 10.1038/Nm.4414  1
2017 Koseki H, Donegá M, Lam BY, Petrova V, van Erp S, Yeo GS, Kwok JC, Ffrench-Constant C, Eva R, Fawcett J. Selective Rab11 transport and the intrinsic regenerative ability of CNS axons. Elife. 6. PMID 28829741 DOI: 10.7554/Elife.26956  1
2017 Larder R, Sim MFM, Gulati P, Antrobus R, Tung YCL, Rimmington D, Ayuso E, Polex-Wolf J, Lam BYH, Dias C, Logan DW, Virtue S, Bosch F, Yeo GSH, Saudek V, et al. Obesity-associated gene TMEM18 has a role in the central control of appetite and body weight regulation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28811369 DOI: 10.1073/Pnas.1707310114  1
2017 Challis BG, Powlson AS, Casey RT, Pearson C, Lam B, Ma M, Pitfield D, Yeo G, Godfrey E, Cheow H, Chatterjee VK, Carroll N, Shaw A, Buscombe J, Simpson HL. Adult-onset hyperinsulinaemic hypoglycaemia in clinical practice: diagnosis, aetiology and management. Endocrine Connections. PMID 28784625 DOI: 10.1530/Ec-17-0076  1
2017 Hameed S, Patterson M, Dhillo WS, Rahman SA, Ma Y, Holton C, Gogakos A, Yeo GSH, Lam BYH, Polex-Wolf J, Fenske W, Bell J, Anastasovska J, Samarut J, Bloom SR, et al. Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight. Cell Reports. 19: 2202-2209. PMID 28614708 DOI: 10.1016/J.Celrep.2017.05.066  1
2017 Lam BYH, Cimino I, Polex-Wolf J, Nicole Kohnke S, Rimmington D, Iyemere V, Heeley N, Cossetti C, Schulte R, Saraiva LR, Logan DW, Blouet C, O'Rahilly S, Coll AP, Yeo GSH. Heterogeneity of hypothalamic pro-opiomelanocortin-expressing neurons revealed by single-cell RNA sequencing. Molecular Metabolism. 6: 383-392. PMID 28462073 DOI: 10.1016/J.Molmet.2017.02.007  1
2017 Nus M, Sage AP, Lu Y, Masters L, Lam BYH, Newland S, Weller S, Tsiantoulas D, Raffort J, Marcus D, Finigan A, Kitt L, Figg N, Schirmbeck R, Kneilling M, ... Yeo GSH, et al. Marginal zone B cells control the response of follicular helper T cells to a high-cholesterol diet. Nature Medicine. PMID 28414328 DOI: 10.1038/Nm.4315  1
2016 Yeo GS. Genetics of obesity: can an old dog teach us new tricks? Diabetologia. PMID 28013339 DOI: 10.1007/S00125-016-4187-X  0.01
2016 Polex-Wolf J, Yeo GS, O'Rahilly S. Impaired prohormone processing: a grand unified theory for features of Prader-Willi syndrome? The Journal of Clinical Investigation. PMID 27941250 DOI: 10.1172/Jci91307  1
2016 Zhou J, Lam B, Neogi SG, Yeo GS, Azizan EA, Brown MJ. Transcriptome Pathway Analysis of Pathological and Physiological Aldosterone-Producing Human Tissues. Hypertension (Dallas, Tex. : 1979). PMID 27777363 DOI: 10.1161/Hypertensionaha.116.08033  1
2016 Zhou J, Lam B, Neogi S, Yeo G, Azizan E, Brown M. ISH ADA-04 TRANSCRIPTOME PATHWAY ANALYSIS OF AUTONOMOUS AND PHYSIOLOGICAL ALDOSTERONE-PRODUCING HUMAN TISSUE. Journal of Hypertension. 34: e40. PMID 27643206 DOI: 10.1097/01.Hjh.0000499958.18632.E9  1
2016 Alfaradhi MZ, Kusinski LC, Fernandez-Twinn DS, Pantaleão LC, Carr SK, Ferland-McCollough D, Yeo GS, Bushell M, Ozanne SE. Maternal obesity in pregnancy developmentally programs adipose tissue inflammation in young, lean male mice offspring. Endocrinology. en20161314. PMID 27583789 DOI: 10.1210/En.2016-1314  1
2016 Kim HS, Cheon JH, Jung ES, Park J, Aum S, Park SJ, Eun S, Lee J, Rüther U, Yeo GS, Ma M, Park KS, Naito T, Kakuta Y, Lee JH, et al. A coding variant in FTO confers susceptibility to thiopurine-induced leukopenia in East Asian patients with IBD. Gut. PMID 27558924 DOI: 10.1136/Gutjnl-2016-311921  1
2016 Zhou J, Lam BY, Neogi SG, Yeo GS, Teo AE, Maniero C, Azizan EA, Brown MJ. [OP.3A.01] THE COMPARISON OF THE TRANSCRIPTOME PROFILE OF THE AUTONOMOUS AND THE PHYSIOLOGICAL ALDOSTERONE-PRODUCING TISSUE, THE ALDOSTERONE-PRODUCING ADENOMA AND THE ZONA GLOMERULOSA. Journal of Hypertension. 34: e26. PMID 27508643 DOI: 10.1097/01.Hjh.0000491398.48468.Bf  1
2016 Adriaenssens AE, Svendsen B, Lam BY, Yeo GS, Holst JJ, Reimann F, Gribble FM. Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets. Diabetologia. PMID 27390011 DOI: 10.1007/S00125-016-4033-1  1
2016 Raffan E, Dennis RJ, O'Donovan CJ, Becker JM, Scott RA, Smith SP, Withers DJ, Wood CJ, Conci E, Clements DN, Summers KM, German AJ, Mellersh CS, Arendt ML, Iyemere VP, ... ... Yeo GS, et al. A Deletion in the Canine POMC Gene Is Associated with Weight and Appetite in Obesity-Prone Labrador Retriever Dogs. Cell Metabolism. PMID 27157046 DOI: 10.1016/J.Cmet.2016.04.012  1
2016 Yavari A, Stocker CJ, Ghaffari S, Wargent ET, Steeples V, Czibik G, Pinter K, Bellahcene M, Woods A, Martínez de Morentin PB, Cansell C, Lam BY, Chuster A, Petkevicius K, Nguyen-Tu MS, ... ... Yeo GS, et al. Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function. Cell Metabolism. PMID 27133129 DOI: 10.1016/J.Cmet.2016.04.003  1
2016 Martin-Gronert MS, Stocker CJ, Wargent ET, Cripps RL, Garfield AS, Jovanovic Z, D'Agostino G, Yeo GS, Cawthorne MA, Arch JR, Heisler LK, Ozanne SE. 5-HT2A and 5-HT2C receptors as hypothalamic targets of developmental programming in male rats. Development (Cambridge, England). 143: e1.2. PMID 27095498 DOI: 10.1242/dev.138396  1
2016 Dalgaard K, Landgraf K, Heyne S, Lempradl A, Longinotto J, Gossens K, Ruf M, Orthofer M, Strogantsev R, Selvaraj M, Lu TT, Casas E, Teperino R, Surani MA, Zvetkova I, ... ... Yeo GS, et al. Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity. Cell. 164: 353-364. PMID 26824653 DOI: 10.1016/J.Cell.2015.12.025  1
2016 Martin-Gronert MS, Stocker CJ, Wargent ET, Cripps RL, Garfield AS, Jovanovic Z, D'Agostino G, Yeo GS, Cawthorne MA, Arch JR, Heisler LK, Ozanne SE. 5-HT2A and 5-HT2C receptors as hypothalamic targets of developmental programming in male rats. Disease Models & Mechanisms. PMID 26769798 DOI: 10.1242/Dev.138396  1
2016 O'Rahilly S, Coll AP, Yeo GS. FTO Obesity Variant and Adipocyte Browning in Humans. The New England Journal of Medicine. 374: 191. PMID 26760098 DOI: 10.1056/Nejmc1513316#Sa2  1
2016 Sandovici I, Hammerle CM, Cooper WN, Smith NH, Tarry-Adkins JL, Dunmore BJ, Bauer J, Andrews SR, Yeo GS, Ozanne SE, Constância M. Ageing is associated with molecular signatures of inflammation and type 2 diabetes in rat pancreatic islets. Diabetologia. 59: 502-11. PMID 26699651 DOI: 10.1007/S00125-015-3837-8  1
2016 Sandovici I, Hammerle CM, Cooper WN, Smith NH, Tarry-Adkins JL, Dunmore BJ, Bauer J, Andrews SR, Yeo GSH, Ozanne SE, Constância M. Ageing is associated with molecular signatures of inflammation and type 2 diabetes in rat pancreatic islets Diabetologia. 59: 502-511. DOI: 10.1007/s00125-015-3837-8  1
2015 Ye L, Goodall JC, Zhang L, Putintseva EV, Lam B, Jiang L, Liu W, Yin J, Lin L, Li T, Wu X, Yeo G, Shugay M, Chudakov DM, Gaston H, et al. TCR usage, gene expression and function of two distinct FOXP3+Treg subsets within CD4(+)CD25(hi) T cells identified by expression of CD39 and CD45RO. Immunology and Cell Biology. PMID 26467610 DOI: 10.1038/Icb.2015.90  1
2015 Richards P, Pais R, Habib AM, Brighton CA, Yeo GS, Reimann F, Gribble FM. High fat diet impairs the function of glucagon-like peptide-1 producing L-cells. Peptides. PMID 26145551 DOI: 10.1016/J.Peptides.2015.06.006  1
2015 Shaikh LH, Zhou J, Teo AE, Garg S, Neogi SG, Figg N, Yeo GS, Yu H, Maguire JJ, Zhao W, Bennett MR, Azizan EA, Davenport AP, McKenzie G, Brown MJ. LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human Adrenal. The Journal of Clinical Endocrinology and Metabolism. 100: E836-44. PMID 25915569 DOI: 10.1210/Jc.2015-1734  1
2015 Tung YC, Gulati P, Liu CH, Rimmington D, Dennis R, Ma M, Saudek V, O'Rahilly S, Coll AP, Yeo GS. FTO is necessary for the induction of leptin resistance by high-fat feeding. Molecular Metabolism. 4: 287-98. PMID 25830092 DOI: 10.1016/J.Molmet.2015.01.011  1
2015 Trivedi C, Shan X, Tung YC, Kabra D, Holland J, Amburgy S, Heppner K, Kirchner H, Yeo GS, Perez-Tilve D. Tachykinin-1 in the central nervous system regulates adiposity in rodents. Endocrinology. 156: 1714-23. PMID 25751638 DOI: 10.1210/En.2014-1781  1
2014 Tung YC, Yeo GS, O'Rahilly S, Coll AP. Obesity and FTO: Changing Focus at a Complex Locus. Cell Metabolism. 20: 710-8. PMID 25448700 DOI: 10.1016/J.Cmet.2014.09.010  1
2014 Heng YH, Zhou B, Harris L, Harvey T, Smith A, Horne E, Martynoga B, Andersen J, Achimastou A, Cato K, Richards LJ, Gronostajski RM, Yeo GS, Guillemot F, Bailey TL, et al. NFIX Regulates Proliferation and Migration Within the Murine SVZ Neurogenic Niche. Cerebral Cortex (New York, N.Y. : 1991). PMID 25331604 DOI: 10.1093/Cercor/Bhu253  1
2014 Gulati P, Avezov E, Ma M, Antrobus R, Lehner P, O'Rahilly S, Yeo GS. Fat mass and obesity-related (FTO) shuttles between the nucleus and cytoplasm. Bioscience Reports. 34. PMID 25242086 DOI: 10.1042/Bsr20140111  1
2014 Yeo GS. The role of the FTO (Fat Mass and Obesity Related) locus in regulating body size and composition. Molecular and Cellular Endocrinology. 397: 34-41. PMID 25224490 DOI: 10.1016/J.Mce.2014.09.012  0.01
2014 Schlosberg A, Lam BY, Yeo GS, Clifton-Bligh RJ. DEFLATE compression algorithm corrects for overestimation of phylogenetic diversity by Grantham approach to single-nucleotide polymorphism classification. International Journal of Molecular Sciences. 15: 8491-508. PMID 24828207 DOI: 10.3390/Ijms15058491  1
2014 Thankamony A, Capalbo D, Marcovecchio ML, Sleigh A, Jørgensen SW, Hill NR, Mooslehner K, Yeo GS, Bluck L, Juul A, Vaag A, Dunger DB. Low circulating levels of IGF-1 in healthy adults are associated with reduced β-cell function, increased intramyocellular lipid, and enhanced fat utilization during fasting. The Journal of Clinical Endocrinology and Metabolism. 99: 2198-207. PMID 24617714 DOI: 10.1210/Jc.2013-4542  1
2014 Moshayedi P, Ng G, Kwok JC, Yeo GS, Bryant CE, Fawcett JW, Franze K, Guck J. The relationship between glial cell mechanosensitivity and foreign body reactions in the central nervous system. Biomaterials. 35: 3919-25. PMID 24529901 DOI: 10.1016/J.Biomaterials.2014.01.038  1
2014 Carr SK, Chen JH, Cooper WN, Constância M, Yeo GS, Ozanne SE. Maternal diet amplifies the hepatic aging trajectory of Cidea in male mice and leads to the development of fatty liver. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 2191-201. PMID 24481968 DOI: 10.1096/Fj.13-242727  1
2014 Loos RJ, Yeo GS. The bigger picture of FTO: the first GWAS-identified obesity gene. Nature Reviews. Endocrinology. 10: 51-61. PMID 24247219 DOI: 10.1038/Nrendo.2013.227  0.01
2013 Goodall JC, Yeo GS. PP2Ce: Fat and stressed out? Molecular Metabolism. 2: 325-6. PMID 24327947 DOI: 10.1016/J.Molmet.2013.08.009  1
2013 Coll AP, Yeo GS. The hypothalamus and metabolism: integrating signals to control energy and glucose homeostasis. Current Opinion in Pharmacology. 13: 970-6. PMID 24075719 DOI: 10.1016/J.Coph.2013.09.010  1
2013 Azizan EA, Poulsen H, Tuluc P, Zhou J, Clausen MV, Lieb A, Maniero C, Garg S, Bochukova EG, Zhao W, Shaikh LH, Brighton CA, Teo AE, Davenport AP, Dekkers T, ... ... Yeo GS, et al. Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. Nature Genetics. 45: 1055-60. PMID 23913004 DOI: 10.1038/Ng.2716  1
2013 Gulati P, Yeo GS. The biology of FTO: from nucleic acid demethylase to amino acid sensor. Diabetologia. 56: 2113-21. PMID 23896822 DOI: 10.1007/S00125-013-2999-5  1
2013 Gulati P, Cheung MK, Antrobus R, Church CD, Harding HP, Tung YC, Rimmington D, Ma M, Ron D, Lehner PJ, Ashcroft FM, Cox RD, Coll AP, O'Rahilly S, Yeo GS. Role for the obesity-related FTO gene in the cellular sensing of amino acids. Proceedings of the National Academy of Sciences of the United States of America. 110: 2557-62. PMID 23359686 DOI: 10.1073/Pnas.1222796110  1
2013 McMurray F, Church CD, Larder R, Nicholson G, Wells S, Teboul L, Tung YC, Rimmington D, Bosch F, Jimenez V, Yeo GS, O'Rahilly S, Ashcroft FM, Coll AP, Cox RD. Adult onset global loss of the fto gene alters body composition and metabolism in the mouse. Plos Genetics. 9: e1003166. PMID 23300482 DOI: 10.1371/Journal.Pgen.1003166  1
2013 Cheung MK, Gulati P, O'Rahilly S, Yeo GS. FTO expression is regulated by availability of essential amino acids. International Journal of Obesity (2005). 37: 744-7. PMID 22614055 DOI: 10.1038/Ijo.2012.77  1
2012 Yeo GS, O'Rahilly S. Uncovering the biology of FTO. Molecular Metabolism. 1: 32-6. PMID 24024116 DOI: 10.1016/J.Molmet.2012.06.001  1
2012 Yeo GS, Heisler LK. Unraveling the brain regulation of appetite: lessons from genetics. Nature Neuroscience. 15: 1343-9. PMID 23007189 DOI: 10.1038/Nn.3211  1
2012 Zito E, Hansen HG, Yeo GS, Fujii J, Ron D. Endoplasmic reticulum thiol oxidase deficiency leads to ascorbic acid depletion and noncanonical scurvy in mice. Molecular Cell. 48: 39-51. PMID 22981861 DOI: 10.1016/J.Molcel.2012.08.010  1
2012 Habib AM, Richards P, Cairns LS, Rogers GJ, Bannon CA, Parker HE, Morley TC, Yeo GS, Reimann F, Gribble FM. Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry. Endocrinology. 153: 3054-65. PMID 22685263 DOI: 10.1210/En.2011-2170  1
2012 Ma M, Harding HP, O'Rahilly S, Ron D, Yeo GS. Kinetic analysis of FTO (fat mass and obesity-associated) reveals that it is unlikely to function as a sensor for 2-oxoglutarate. The Biochemical Journal. 444: 183-7. PMID 22435707 DOI: 10.1042/Bj20120065  1
2012 Yeo GS. FTO and obesity: a problem for a billion people. Journal of Neuroendocrinology. 24: 393-4. PMID 22248259 DOI: 10.1111/J.1365-2826.2011.02254.X  0.01
2012 Klus P, Lam S, Lyberg D, Cheung MS, Pullan G, McFarlane I, Yeo GSh, Lam BY. BarraCUDA - a fast short read sequence aligner using graphics processing units. Bmc Research Notes. 5: 27. PMID 22244497 DOI: 10.1186/1756-0500-5-27  1
2011 Cheung MK, Yeo GS. FTO Biology and Obesity: Why Do a Billion of Us Weigh 3 kg More? Frontiers in Endocrinology. 2: 4. PMID 22649359 DOI: 10.3389/Fendo.2011.00004  1
2011 Yeo GS. Where next for GWAS? Briefings in Functional Genomics. 10: 51. PMID 21436301 DOI: 10.1093/Bfgp/Elr011  0.01
2011 Tung YC, Yeo GS. From GWAS to biology: lessons from FTO. Annals of the New York Academy of Sciences. 1220: 162-71. PMID 21388413 DOI: 10.1111/J.1749-6632.2010.05903.X  1
2011 Shan X, Yeo GSH. Central leptin and ghrelin signalling: Comparing and contrasting their mechanisms of action in the brain Reviews in Endocrine and Metabolic Disorders. 12: 197-209. PMID 21331644 DOI: 10.1007/S11154-011-9171-7  1
2011 van Oterendorp C, Lorber B, Jovanovic Z, Yeo G, Lagrèze WA, Martin KR. The expression of dynein light chain DYNLL1 (LC8-1) is persistently downregulated in glaucomatous rat retinal ganglion cells Experimental Eye Research. 92: 138-146. PMID 21145319 DOI: 10.1016/J.Exer.2010.11.013  1
2011 Larder R, Cheung MK, Tung YC, Yeo GS, Coll AP. Where to go with FTO? Trends in Endocrinology and Metabolism: Tem. 22: 53-9. PMID 21131211 DOI: 10.1016/J.Tem.2010.11.001  1
2011 Gumy LF, Yeo GS, Tung YC, Zivraj KH, Willis D, Coppola G, Lam BY, Twiss JL, Holt CE, Fawcett JW. Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization. Rna (New York, N.Y.). 17: 85-98. PMID 21098654 DOI: 10.1261/Rna.2386111  1
2010 Zivraj KH, Tung YC, Piper M, Gumy L, Fawcett JW, Yeo GS, Holt CE. Subcellular profiling reveals distinct and developmentally regulated repertoire of growth cone mRNAs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15464-78. PMID 21084603 DOI: 10.1523/Jneurosci.1800-10.2010  1
2010 Tung YC, Yeo GS. Central melanocortin signaling regulates cholesterol. Nature Neuroscience. 13: 779-80. PMID 20581809 DOI: 10.1038/Nn0710-779  1
2010 Jovanovic Z, Yeo GS. Central leptin signalling: beyond the arcuate nucleus. Autonomic Neuroscience : Basic & Clinical. 156: 8-14. PMID 20547475 DOI: 10.1016/J.Autneu.2010.05.008  1
2010 Chen JH, Tarry-Adkins JL, Matharu K, Yeo GS, Ozanne SE. Maternal protein restriction affects gene expression profiles in the kidney at weaning with implications for the regulation of renal function and lifespan. Clinical Science (London, England : 1979). 119: 373-84. PMID 20528770 DOI: 10.1042/Cs20100230  1
2010 Tung YC, Ayuso E, Shan X, Bosch F, O'Rahilly S, Coll AP, Yeo GS. Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats. Plos One. 5: e8771. PMID 20098739 DOI: 10.1371/Journal.Pone.0008771  1
2010 Corander MP, Challis BG, Thompson EL, Jovanovic Z, Loraine Tung YC, Rimmington D, Huhtaniemi IT, Murphy KG, Topaloglu AK, Yeo GSH, O'Rahilly S, Dhillo WS, Semple RK, Coll AP. The effects of neurokinin B upon gonadotrophin release in male rodents Journal of Neuroendocrinology. 22: 181-187. PMID 20041982 DOI: 10.1111/J.1365-2826.2009.01951.X  1
2010 Romeo S, Sentinelli F, Dash S, Yeo GS, Savage DB, Leonetti F, Capoccia D, Incani M, Maglio C, Iacovino M, O'Rahilly S, Baroni MG. Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent. International Journal of Obesity (2005). 34: 190-4. PMID 19844213 DOI: 10.1038/Ijo.2009.216  1
2010 Meyre D, Proulx K, Kawagoe-Takaki H, Vatin V, Gutiérrez-Aguilar R, Lyon D, Ma M, Choquet H, Horber F, Van Hul W, Van Gaal L, Balkau B, Visvikis-Siest S, Pattou F, Farooqi IS, ... ... Yeo GS, et al. Prevalence of loss-of-function FTO mutations in lean and obese individuals. Diabetes. 59: 311-8. PMID 19833892 DOI: 10.2337/Db09-0703  1
2009 Boissel S, Reish O, Proulx K, Kawagoe-Takaki H, Sedgwick B, Yeo GS, Meyre D, Golzio C, Molinari F, Kadhom N, Etchevers HC, Saudek V, Farooqi IS, Froguel P, Lindahl T, et al. Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations. American Journal of Human Genetics. 85: 106-11. PMID 19559399 DOI: 10.1016/J.Ajhg.2009.06.002  1
2009 de Smith AJ, Purmann C, Walters RG, Ellis RJ, Holder SE, Van Haelst MM, Brady AF, Fairbrother UL, Dattani M, Keogh JM, Henning E, Yeo GS, O'Rahilly S, Froguel P, Farooqi IS, et al. A deletion of the HBII-85 class of small nucleolar RNAs (snoRNAs) is associated with hyperphagia, obesity and hypogonadism. Human Molecular Genetics. 18: 3257-65. PMID 19498035 DOI: 10.1093/Hmg/Ddp263  1
2009 Dash S, Sano H, Rochford JJ, Semple RK, Yeo G, Hyden CS, Soos MA, Clark J, Rodin A, Langenberg C, Druet C, Fawcett KA, Tung YC, Wareham NJ, Barroso I, et al. A truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia. Proceedings of the National Academy of Sciences of the United States of America. 106: 9350-5. PMID 19470471 DOI: 10.1073/Pnas.0900909106  1
2009 Tan K, Pogozheva ID, Yeo GS, Hadaschik D, Keogh JM, Haskell-Leuvano C, O'Rahilly S, Mosberg HI, Farooqi IS. Functional characterization and structural modeling of obesity associated mutations in the melanocortin 4 receptor. Endocrinology. 150: 114-25. PMID 18801902 DOI: 10.1210/En.2008-0721  1
2008 Tung YCL, Ma M, Piper S, Coll A, O'Rahilly S, Yeo GSH. Novel leptin-regulated genes revealed by transcriptional profiling of the hypothalamic paraventricular nucleus Journal of Neuroscience. 28: 12419-12426. PMID 19020034 DOI: 10.1523/Jneurosci.3412-08.2008  1
2008 Coll AP, Yeo GS, Farooqi IS, O'Rahilly S. SnapShot: the hormonal control of food intake. Cell. 135: 572.e1-2. PMID 18984167 DOI: 10.1016/J.Cell.2008.10.014  1
2008 Lam DD, Przydzial MJ, Ridley SH, Yeo GS, Rochford JJ, O'Rahilly S, Heisler LK. Serotonin 5-HT2C receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptors. Endocrinology. 149: 1323-8. PMID 18039773 DOI: 10.1210/En.2007-1321  1
2007 Gerken T, Girard CA, Tung YC, Webby CJ, Saudek V, Hewitson KS, Yeo GS, McDonough MA, Cunliffe S, McNeill LA, Galvanovskis J, Rorsman P, Robins P, Prieur X, Coll AP, et al. The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science (New York, N.Y.). 318: 1469-72. PMID 17991826 DOI: 10.1126/Science.1151710  1
2007 Heisler LK, Pronchuk N, Nonogaki K, Zhou L, Raber J, Tung L, Yeo GS, O'Rahilly S, Colmers WF, Elmquist JK, Tecott LH. Serotonin activates the hypothalamic-pituitary-adrenal axis via serotonin 2C receptor stimulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 6956-64. PMID 17596444 DOI: 10.1523/Jneurosci.2584-06.2007  1
2007 Medina-Gomez G, Gray SL, Yetukuri L, Shimomura K, Virtue S, Campbell M, Curtis RK, Jimenez-Linan M, Blount M, Yeo GS, Lopez M, Seppänen-Laakso T, Ashcroft FM, Oresic M, Vidal-Puig A. PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism. Plos Genetics. 3: e64. PMID 17465682 DOI: 10.1371/Journal.Pgen.0030064  1
2007 Goodall JC, Ellis L, Yeo GS, Gaston JS. Does HLA-B27 influence the monocyte inflammatory response to lipopolysaccharide? Rheumatology (Oxford, England). 46: 232-7. PMID 16877465 DOI: 10.1093/Rheumatology/Kel226  1
2007 Gray J, Yeo G, Hung C, Keogh J, Clayton P, Banerjee K, McAulay A, O'Rahilly S, Farooqi IS. Functional characterization of human NTRK2 mutations identified in patients with severe early-onset obesity International Journal of Obesity. 31: 359-364. PMID 16702999 DOI: 10.1038/Sj.Ijo.0803390  1
2006 Gray J, Yeo GS, Cox JJ, Morton J, Adlam AL, Keogh JM, Yanovski JA, El Gharbawy A, Han JC, Tung YC, Hodges JR, Raymond FL, O'rahilly S, Farooqi IS. Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene. Diabetes. 55: 3366-71. PMID 17130481 DOI: 10.2337/Db06-0550  1
2006 Gray SL, Dalla Nora E, Grosse J, Manieri M, Stoeger T, Medina-Gomez G, Burling K, Wattler S, Russ A, Yeo GSH, Chatterjee VK, O'Rahilly S, Voshol PJ, Cinti S, Vidal-Puig A. Leptin deficiency unmasks the deleterious effects of impaired peroxisome proliferator-activated receptor γ function (P465L PPARγ) in mice Diabetes. 55: 2669-2677. PMID 17003330 DOI: 10.2337/Db06-0389  1
2006 Pett MR, Herdman MT, Palmer RD, Yeo GS, Shivji MK, Stanley MA, Coleman N. Selection of cervical keratinocytes containing integrated HPV16 associates with episome loss and an endogenous antiviral response. Proceedings of the National Academy of Sciences of the United States of America. 103: 3822-7. PMID 16505361 DOI: 10.1073/Pnas.0600078103  0.01
2006 Lee YS, Challis BG, Thompson DA, Yeo GS, Keogh JM, Madonna ME, Wraight V, Sims M, Vatin V, Meyre D, Shield J, Burren C, Ibrahim Z, Cheetham T, Swift P, et al. A POMC variant implicates beta-melanocyte-stimulating hormone in the control of human energy balance. Cell Metabolism. 3: 135-40. PMID 16459314 DOI: 10.1016/J.Cmet.2006.01.006  1
2005 Coll AP, Challis BG, López M, Piper S, Yeo GSH, O'Rahilly S. Proopiomelanocortin-deficient mice are hypersensitive to the adverse metabolic effects of glucocorticoids Diabetes. 54: 2269-2276. PMID 16046291 DOI: 10.2337/Diabetes.54.8.2269  1
2005 Lelliott CJ, López M, Curtis RK, Parker N, Laudes M, Yeo G, Jimenez-Liñan M, Grosse J, Saha AK, Wiggins D, Hauton D, Brand MD, O'Rahilly S, Griffin JL, Gibbons GF, et al. Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1108-19. PMID 15985534 DOI: 10.1096/Fj.04-3196Com  1
2005 Coll AP, Challis BG, Yeo GSH, Farooqi IS, Rahilly SO. Melanocortin receptors and energy homeostasis Current Opinion in Endocrinology & Diabetes. 12: 205-210. DOI: 10.1097/01.Med.0000162078.80344.35  1
2004 Yeo GS, Connie Hung CC, Rochford J, Keogh J, Gray J, Sivaramakrishnan S, O'Rahilly S, Farooqi IS. A de novo mutation affecting human TrkB associated with severe obesity and developmental delay. Nature Neuroscience. 7: 1187-9. PMID 15494731 DOI: 10.1038/Nn1336  1
2004 Hung CC, Pirie F, Luan J, Lank E, Motala A, Yeo GS, Keogh JM, Wareham NJ, O'Rahilly S, Farooqi IS. Studies of the peptide YY and neuropeptide Y2 receptor genes in relation to human obesity and obesity-related traits. Diabetes. 53: 2461-6. PMID 15331560 DOI: 10.2337/Diabetes.53.9.2461  1
2004 Sandilands A, Yeo G, Brown MJ, O'Shaughnessy KM. Functional responses of human beta1 adrenoceptors with defined haplotypes for the common 389R>G and 49S>G polymorphisms. Pharmacogenetics. 14: 343-9. PMID 15247626 DOI: 10.1097/00008571-200406000-00003  1
2004 Coll AP, Challis BG, Yeo GS, Snell K, Piper SJ, Halsall D, Thresher RR, O'Rahilly S. The effects of proopiomelanocortin deficiency on murine adrenal development and responsiveness to adrenocorticotropin. Endocrinology. 145: 4721-7. PMID 15231703 DOI: 10.1210/En.2004-0491  1
2004 Coll AP, Farooqi IS, Challis BG, Yeo GS, O'Rahilly S. Proopiomelanocortin and energy balance: insights from human and murine genetics. The Journal of Clinical Endocrinology and Metabolism. 89: 2557-62. PMID 15181023 DOI: 10.1210/Jc.2004-0428  1
2004 Challis BG, Coll AP, Yeo GS, Pinnock SB, Dickson SL, Thresher RR, Dixon J, Zahn D, Rochford JJ, White A, Oliver RL, Millington G, Aparicio SA, Colledge WH, Russ AP, et al. Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36). Proceedings of the National Academy of Sciences of the United States of America. 101: 4695-700. PMID 15070780 DOI: 10.1073/Pnas.0306931101  1
2004 O'Rahilly S, Yeo GS, Farooqi IS. Melanocortin receptors weigh in. Nature Medicine. 10: 351-2. PMID 15057231 DOI: 10.1038/Nm0404-351  1
2004 Laudes M, Barroso I, Luan J, Soos MA, Yeo G, Meirhaeghe A, Logie L, Vidal-Puig A, Schafer AJ, Wareham NJ, O'Rahilly S. Genetic variants in human sterol regulatory element binding protein-1c in syndromes of severe insulin resistance and type 2 diabetes. Diabetes. 53: 842-6. PMID 14988272 DOI: 10.2337/Diabetes.53.3.842  1
2003 Donohoue PA, Tao YX, Collins M, Yeo GS, O'Rahilly S, Segaloff DL. Deletion of codons 88-92 of the melanocortin-4 receptor gene: a novel deleterious mutation in an obese female. The Journal of Clinical Endocrinology and Metabolism. 88: 5841-5. PMID 14671178 DOI: 10.1210/Jc.2003-030903  1
2003 Yeo GS, Siddle K. Attractin' more attention - new pieces in the obesity puzzle? The Biochemical Journal. 376: e7-8. PMID 14656215 DOI: 10.1042/Bj20031675  1
2003 O'Rahilly S, Farooqi IS, Yeo GS, Challis BG. Minireview: human obesity-lessons from monogenic disorders. Endocrinology. 144: 3757-64. PMID 12933645 DOI: 10.1210/En.2003-0373  1
2003 Farooqi IS, Yeo GS, O'Rahilly S. Binge eating as a phenotype of melanocortin 4 receptor gene mutations. The New England Journal of Medicine. 349: 606-9; author reply . PMID 12908459  1
2003 Hung CC, Farooqi IS, Ong K, Luan J, Keogh JM, Pembrey M, Yeo GS, Dunger D, Wareham NJ, O' Rahilly S. Contribution of variants in the small heterodimer partner gene to birthweight, adiposity, and insulin levels: mutational analysis and association studies in multiple populations. Diabetes. 52: 1288-91. PMID 12716767 DOI: 10.2337/Diabetes.52.5.1288  1
2003 Meirhaeghe A, Crowley V, Lenaghan C, Lelliott C, Green K, Stewart A, Hart K, Schinner S, Sethi JK, Yeo G, Brand MD, Cortright RN, O'Rahilly S, Montague C, Vidal-Puig AJ. Characterization of the human, mouse and rat PGC1 beta (peroxisome-proliferator-activated receptor-gamma co-activator 1 beta) gene in vitro and in vivo. The Biochemical Journal. 373: 155-65. PMID 12678921 DOI: 10.1042/Bj20030200  1
2003 Farooqi IS, Keogh JM, Yeo GS, Lank EJ, Cheetham T, O'Rahilly S. Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene. The New England Journal of Medicine. 348: 1085-95. PMID 12646665 DOI: 10.1056/Nejmoa022050  1
2003 Yeo GS, Lank EJ, Farooqi IS, Keogh J, Challis BG, O'Rahilly S. Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms. Human Molecular Genetics. 12: 561-74. PMID 12588803 DOI: 10.1093/Hmg/Ddg057  1
2002 Challis BG, Yeo GS. Past, present and future strategies to study the genetics of body weight regulation. Briefings in Functional Genomics & Proteomics. 1: 290-304. PMID 15239895 DOI: 10.1093/Bfgp/1.3.290  1
2002 Berger D, Barroso I, Soos M, Yeo G, Schafer AJ, O'Rahilly S, Whitehead JP. Genetic variants of insulin receptor substrate-1 (IRS-1) in syndromes of severe insulin resistance. Functional analysis of Ala513Pro and Gly1158Glu IRS-1. Diabetic Medicine : a Journal of the British Diabetic Association. 19: 804-9. PMID 12358865 DOI: 10.1046/J.1464-5491.2002.00779.X  1
2002 Mulligan C, Rochford J, Denyer G, Stephens R, Yeo G, Freeman T, Siddle K, O'Rahilly S. Microarray analysis of insulin and insulin-like growth factor-1 (IGF-1) receptor signaling reveals the selective up-regulation of the mitogen heparin-binding EGF-like growth factor by IGF-1. The Journal of Biological Chemistry. 277: 42480-7. PMID 12213819 DOI: 10.1074/Jbc.M206206200  1
2002 Challis BG, Pritchard LE, Creemers JWM, Delplanque J, Keogh JM, Luan J, Wareham NJ, Yeo GSH, Bhattacharyya S, Froguel P, White A, Sadaf Farooqi I, O'Rahilly S. A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism Human Molecular Genetics. 11: 1997-2004. PMID 12165561 DOI: 10.1093/Hmg/11.17.1997  1
2002 Crowley VE, Yeo GS, O'Rahilly S. Obesity therapy: altering the energy intake-and-expenditure balance sheet. Nature Reviews. Drug Discovery. 1: 276-86. PMID 12120279 DOI: 10.1038/Nrd770  1
2001 Goodall JC, Yeo G, Huang M, Raggiaschi R, Gaston JS. Identification of Chlamydia trachomatis antigens recognized by human CD4+ T lymphocytes by screening an expression library. European Journal of Immunology. 31: 1513-22. PMID 11465108 DOI: 10.1002/1521-4141(200105)31:5<1513::Aid-Immu1513>3.0.Co;2-U  1
1999 Elgar G, Clark MS, Meek S, Smith S, Warner S, Edwards YJ, Bouchireb N, Cottage A, Yeo GS, Umrania Y, Williams G, Brenner S. Generation and analysis of 25 Mb of genomic DNA from the pufferfish Fugu rubripes by sequence scanning. Genome Research. 9: 960-71. PMID 10523524 DOI: 10.1101/Gr.9.10.960  1
1999 De Angelis E, MacFarlane J, Du JS, Yeo G, Hicks R, Rathjen FG, Kenwrick S, Brümmendorf T. Pathological missense mutations of neural cell adhesion molecule L1 affect homophilic and heterophilic binding activities. The Embo Journal. 18: 4744-53. PMID 10469653 DOI: 10.1093/Emboj/18.17.4744  0.01
1997 Yeo GS, Elgar G, Sandford R, Brenner S. Cloning and sequencing of complement component C9 and its linkage to DOC-2 in the pufferfish Fugu rubripes. Gene. 200: 203-11. PMID 9373156 DOI: 10.1016/S0378-1119(97)00423-X  1
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