Joel Elmquist - Publications

Affiliations: 
University of Texas Southwestern, Dallas, TX, United States 
Area:
feeding and metabolism

163 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Castorena CM, Caron A, Michael NJ, Ahmed NI, Arnold AG, Lee J, Lee CE, Limboy C, Tinajero AS, Granier M, Wang S, Horton JD, Holland WL, Lee S, Liu C, ... ... Elmquist JK, et al. CB1Rs in VMH Neurons Regulate Glucose Homeostasis but not Body Weight. American Journal of Physiology. Endocrinology and Metabolism. PMID 34097543 DOI: 10.1152/ajpendo.00044.2021  0.82
2021 Gupta D, Patterson AM, Osborne-Lawrence S, Bookout AL, Varshney S, Shankar K, Singh O, Metzger NP, Richard CP, Wyler SC, Elmquist JK, Zigman JM. Disrupting the ghrelin-growth hormone axis limits ghrelin's orexigenic but not glucoregulatory actions. Molecular Metabolism. 101258. PMID 34023483 DOI: 10.1016/j.molmet.2021.101258  0.621
2020 Jia L, Lee S, Tierney JA, Elmquist JK, Burton MD, Gautron L. TLR4 signaling selectively and directly promotes CGRP release from vagal afferents in the mouse. Eneuro. PMID 33318075 DOI: 10.1523/ENEURO.0254-20.2020  0.586
2020 Michael NJ, Elmquist JK. Coordination of metabolism, arousal, and reward by orexin/hypocretin neurons. The Journal of Clinical Investigation. 130: 4540-4542. PMID 32804153 DOI: 10.1172/Jci140585  0.8
2020 Michael NJ, Zigman JM, Williams KW, Elmquist JK. Electrophysiological Properties of Genetically Identified Histaminergic Neurons. Neuroscience. PMID 32599122 DOI: 10.1016/J.Neuroscience.2020.06.031  0.811
2020 Michael NJ, Caron A, Lee CE, Castorena CM, Lee S, Zigman JM, Williams KW, Elmquist JK. Melanocortin regulation of histaminergic neurons via perifornical lateral hypothalamic melanocortin 4 receptors. Molecular Metabolism. 35: 100956. PMID 32244183 DOI: 10.1016/J.Molmet.2020.01.020  0.823
2019 Mani BK, Castorena CM, Vianna CR, Lee CE, Metzger NP, Vijayaraghavan P, Osborne-Lawrence S, Elmquist JK, Zigman JM. Combined Loss of Ghrelin Receptor and Cannabinoid CB1 Receptor in Mice Decreases Survival but Does Not Additively Reduce Body Weight or Eating. Neuroscience. PMID 31520709 DOI: 10.1016/J.Neuroscience.2019.09.005  0.612
2019 Zhao S, Zhu Y, Schultz RD, Li N, He Z, Zhang Z, Caron A, Zhu Q, Sun K, Xiong W, Deng H, Sun J, Deng Y, Kim M, Lee CE, ... ... Elmquist JK, et al. Partial Leptin Reduction as an Insulin Sensitization and Weight Loss Strategy. Cell Metabolism. PMID 31495688 DOI: 10.1016/J.Cmet.2019.08.005  0.792
2019 Caron A, Reynolds RP, Castorena CM, Michael NJ, Lee CE, Lee S, Berdeaux R, Scherer PE, Elmquist JK. Adipocyte Gs but not Gi signaling regulates whole-body glucose homeostasis. Molecular Metabolism. PMID 31279640 DOI: 10.1016/J.Molmet.2019.06.019  0.8
2019 Amoasii L, Sanchez-Ortiz E, Fujikawa T, Elmquist JK, Bassel-Duby R, Olson EN. NURR1 activation in skeletal muscle controls systemic energy homeostasis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31110021 DOI: 10.1073/Pnas.1902490116  0.505
2019 Xu Y, Nedungadi TP, Zhu L, Sobhani N, Irani BG, Davis KE, Zhang X, Zou F, Gent LM, Hahner LD, Khan SA, Elias CF, Elmquist JK, Clegg DJ. Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction. Cell Metabolism. 29: 1232. PMID 31067449 DOI: 10.1016/J.Cmet.2019.04.006  0.466
2019 Cappel DA, Deja S, Duarte JAG, Kucejova B, Iñigo M, Fletcher JA, Fu X, Berglund ED, Liu T, Elmquist JK, Hammer S, Mishra P, Browning JD, Burgess SC. Pyruvate-Carboxylase-Mediated Anaplerosis Promotes Antioxidant Capacity by Sustaining TCA Cycle and Redox Metabolism in Liver. Cell Metabolism. PMID 31006591 DOI: 10.1016/J.Cmet.2019.03.014  0.471
2018 Caron A, Dungan Lemko HM, Castorena CM, Fujikawa T, Lee S, Lord CC, Ahmed N, Lee CE, Holland WL, Liu C, Elmquist JK. POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels. Elife. 7. PMID 29528284 DOI: 10.7554/Elife.33710  0.803
2018 Caron A, Lee S, Elmquist JK, Gautron L. Leptin and brain-adipose crosstalks. Nature Reviews. Neuroscience. 19: 153-165. PMID 29449715 DOI: 10.1038/Nrn.2018.7  0.655
2018 Mani BK, Castorena CM, Osborne-Lawrence S, Vijayaraghavan P, Metzger NP, Elmquist JK, Zigman JM. Ghrelin mediates exercise endurance and the feeding response post-exercise. Molecular Metabolism. PMID 29396372 DOI: 10.1016/J.Molmet.2018.01.006  0.572
2018 Burton M, Szabo-Pardi T, Milligan A, Castorena C, Dussor G, Elmquist J, Price T. Peripheral nociceptors are not responsible for mediating the analgesic actions of CB1R The Journal of Pain. 19: S3. DOI: 10.1016/J.Jpain.2017.12.020  0.737
2017 Mountjoy KG, Caron A, Hubbard K, Shome A, Grey AC, Sun B, Bould S, Middleditch M, Pontré B, McGregor A, Harris PWR, Kowalczyk R, Brimble MA, Botha R, Tan KML, ... ... Elmquist JK, et al. Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance. Molecular Metabolism. PMID 29226825 DOI: 10.1016/J.Molmet.2017.11.008  0.563
2017 Udit S, Burton M, Rutkowski JM, Lee S, Bookout AL, Scherer PE, Elmquist JK, Gautron L. Nav1.8 neurons are involved in limiting acute phase responses to dietary fat. Molecular Metabolism. 6: 1081-1091. PMID 29031710 DOI: 10.1016/J.Molmet.2017.07.012  0.679
2017 Wyler SC, Lord CC, Lee S, Elmquist JK, Liu C. Serotonergic Control of Metabolic Homeostasis. Frontiers in Cellular Neuroscience. 11: 277. PMID 28979187 DOI: 10.3389/Fncel.2017.00277  0.351
2017 Fujikawa T, Castorena CM, Lee S, Elmquist JK. The Hypothalamic Regulation of Metabolic Adaptations to Exercise. Journal of Neuroendocrinology. PMID 28887871 DOI: 10.1111/Jne.12533  0.495
2017 Lord CC, Wyler SC, Wan R, Castorena CM, Ahmed N, Mathew D, Lee S, Liu C, Elmquist JK. The atypical antipsychotic olanzapine causes weight gain by targeting serotonin receptor 2C. The Journal of Clinical Investigation. PMID 28805659 DOI: 10.1172/Jci93362  0.429
2017 Xu Y, O'Malley BW, Elmquist JK. Brain nuclear receptors and body weight regulation. The Journal of Clinical Investigation. 127: 1172-1180. PMID 28218618 DOI: 10.1172/Jci88891  0.417
2016 Fujikawa T, Castorena CM, Pearson M, Kusminski CM, Ahmed N, Battiprolu PK, Kim KW, Lee S, Hill JA, Scherer PE, Holland WL, Elmquist JK. SF-1 expression in the hypothalamus is required for beneficial metabolic effects of exercise. Elife. 5. PMID 27874828 DOI: 10.7554/Elife.18206  0.537
2016 Sohn JW, Oh Y, Kim KW, Lee S, Williams KW, Elmquist JK. Leptin and insulin engage specific PI3K subunits in hypothalamic SF1 neurons. Molecular Metabolism. 5: 669-79. PMID 27656404 DOI: 10.1016/j.molmet.2016.06.004  0.747
2016 Zhu Y, Gao Y, Tao C, Shao M, Zhao S, Huang W, Yao T, Johnson JA, Liu T, Cypess AM, Gupta O, Holland WL, Gupta RK, Spray DC, Tanowitz HB, ... ... Elmquist JK, et al. Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals. Cell Metabolism. 24: 420-433. PMID 27626200 DOI: 10.1016/J.Cmet.2016.08.005  0.773
2015 Garfield AS, Li C, Madara JC, Shah BP, Webber E, Steger JS, Campbell JN, Gavrilova O, Lee CE, Olson DP, Elmquist JK, Tannous BA, Krashes MJ, Lowell BB. A neural basis for melanocortin-4 receptor-regulated appetite. Nature Neuroscience. 18: 863-71. PMID 25915476 DOI: 10.1038/Nn.4011  0.446
2015 Yan C, Yang Y, Saito K, Xu P, Wang C, Hinton AO, Yan X, Wu Q, Tong Q, Elmquist JK, Fukuda M, Xu Y. Meta-chlorophenylpiperazine enhances leptin sensitivity in diet-induced obese mice. British Journal of Pharmacology. 172: 3510-21. PMID 25817043 DOI: 10.1111/Bph.13141  0.506
2015 Gautron L, Elmquist JK, Williams KW. Neural control of energy balance: translating circuits to therapies. Cell. 161: 133-45. PMID 25815991 DOI: 10.1016/j.cell.2015.02.023  0.56
2015 Koch M, Varela L, Kim JG, Kim JD, Hernández-Nuño F, Simonds SE, Castorena CM, Vianna CR, Elmquist JK, Morozov YM, Rakic P, Bechmann I, Cowley MA, Szigeti-Buck K, Dietrich MO, et al. Hypothalamic POMC neurons promote cannabinoid-induced feeding. Nature. 519: 45-50. PMID 25707796 DOI: 10.1038/Nature14260  0.38
2014 Kohno D, Lee S, Harper MJ, Kim KW, Sone H, Sasaki T, Kitamura T, Fan G, Elmquist JK. Dnmt3a in Sim1 neurons is necessary for normal energy homeostasis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15288-96. PMID 25392496 DOI: 10.1523/Jneurosci.1316-14.2014  0.363
2014 Shah BP, Vong L, Olson DP, Koda S, Krashes MJ, Ye C, Yang Z, Fuller PM, Elmquist JK, Lowell BB. MC4R-expressing glutamatergic neurons in the paraventricular hypothalamus regulate feeding and are synaptically connected to the parabrachial nucleus. Proceedings of the National Academy of Sciences of the United States of America. 111: 13193-8. PMID 25157144 DOI: 10.1073/Pnas.1407843111  0.418
2014 Williams KW, Liu T, Kong X, Fukuda M, Deng Y, Berglund ED, Deng Z, Gao Y, Liu T, Sohn JW, Jia L, Fujikawa T, Kohno D, Scott MM, Lee S, ... ... Elmquist JK, et al. Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis. Cell Metabolism. 20: 471-82. PMID 25017942 DOI: 10.1016/J.Cmet.2014.06.002  0.827
2014 Berglund ED, Liu T, Kong X, Sohn JW, Vong L, Deng Z, Lee CE, Lee S, Williams KW, Olson DP, Scherer PE, Lowell BB, Elmquist JK. Melanocortin 4 receptors in autonomic neurons regulate thermogenesis and glycemia. Nature Neuroscience. 17: 911-3. PMID 24908101 DOI: 10.1038/Nn.3737  0.836
2014 Jia L, Vianna CR, Fukuda M, Berglund ED, Liu C, Tao C, Sun K, Liu T, Harper MJ, Lee CE, Lee S, Scherer PE, Elmquist JK. Hepatocyte Toll-like receptor 4 regulates obesity-induced inflammation and insulin resistance. Nature Communications. 5: 3878. PMID 24815961 DOI: 10.1038/Ncomms4878  0.407
2014 Liu C, Bookout AL, Lee S, Sun K, Jia L, Lee C, Udit S, Deng Y, Scherer PE, Mangelsdorf DJ, Gautron L, Elmquist JK. PPARγ in vagal neurons regulates high-fat diet induced thermogenesis. Cell Metabolism. 19: 722-30. PMID 24703703 DOI: 10.1016/J.Cmet.2014.01.021  0.507
2014 Liu C, Lee S, Elmquist JK. Circuits controlling energy balance and mood: inherently intertwined or just complicated intersections? Cell Metabolism. 19: 902-9. PMID 24630814 DOI: 10.1016/J.Cmet.2014.02.008  0.321
2014 Asterholm IW, Rutkowski JM, Fujikawa T, Cho YR, Fukuda M, Tao C, Wang ZV, Gupta RK, Elmquist JK, Scherer PE. Elevated resistin levels induce central leptin resistance and increased atherosclerotic progression in mice. Diabetologia. 57: 1209-18. PMID 24623101 DOI: 10.1007/S00125-014-3210-3  0.527
2014 Wang Q, Liu C, Uchida A, Chuang JC, Walker A, Liu T, Osborne-Lawrence S, Mason BL, Mosher C, Berglund ED, Elmquist JK, Zigman JM. Arcuate AgRP neurons mediate orexigenic and glucoregulatory actions of ghrelin. Molecular Metabolism. 3: 64-72. PMID 24567905 DOI: 10.1016/J.Molmet.2013.10.001  0.82
2014 Berglund ED, Liu C, Sohn JW, Liu T, Kim MH, Lee CE, Vianna CR, Williams KW, Xu Y, Elmquist JK. Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis (Journal of Clinical Investigation (2014) 124, 4 (1868) DOI: 10.1172/JCI75669) Journal of Clinical Investigation. 124: 1868.  0.719
2013 Berglund ED, Liu C, Sohn JW, Liu T, Kim MH, Lee CE, Vianna CR, Williams KW, Xu Y, Elmquist JK. Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis. The Journal of Clinical Investigation. 123: 5061-70. PMID 24177424 DOI: 10.1172/Jci70338  0.787
2013 Fujikawa T, Berglund ED, Patel VR, Ramadori G, Vianna CR, Vong L, Thorel F, Chera S, Herrera PL, Lowell BB, Elmquist JK, Baldi P, Coppari R. Leptin engages a hypothalamic neurocircuitry to permit survival in the absence of insulin. Cell Metabolism. 18: 431-44. PMID 24011077 DOI: 10.1016/J.Cmet.2013.08.004  0.594
2013 Liu T, Elmquist JK, Williams KW. Mrap2: an accessory protein linked to obesity. Cell Metabolism. 18: 309-11. PMID 24011068 DOI: 10.1016/j.cmet.2013.08.016  0.569
2013 Sohn JW, Elmquist JK, Williams KW. Neuronal circuits that regulate feeding behavior and metabolism. Trends in Neurosciences. 36: 504-12. PMID 23790727 DOI: 10.1016/j.tins.2013.05.003  0.708
2013 Gautron L, Rutkowski JM, Burton MD, Wei W, Wan Y, Elmquist JK. Neuronal and nonneuronal cholinergic structures in the mouse gastrointestinal tract and spleen. The Journal of Comparative Neurology. 521: 3741-67. PMID 23749724 DOI: 10.1002/Cne.23376  0.639
2013 Atkin SD, Owen BM, Bookout AL, Cravo RM, Lee C, Elias CF, Elmquist JK, Kliewer SA, Mangelsdorf DJ. Nuclear receptor LRH-1 induces the reproductive neuropeptide kisspeptin in the hypothalamus. Molecular Endocrinology (Baltimore, Md.). 27: 598-605. PMID 23504956 DOI: 10.1210/me.2012-1371  0.386
2013 Gautron L, Cravo RM, Elmquist JK, Elias CF. Discrete melanocortin-sensitive neuroanatomical pathway linking the ventral premmamillary nucleus to the paraventricular hypothalamus. Neuroscience. 240: 70-82. PMID 23485805 DOI: 10.1016/j.neuroscience.2013.02.024  0.336
2013 Frazão R, Cravo RM, Donato J, Ratra DV, Clegg DJ, Elmquist JK, Zigman JM, Williams KW, Elias CF. Shift in Kiss1 cell activity requires estrogen receptor α. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2807-20. PMID 23407940 DOI: 10.1523/Jneurosci.1610-12.2013  0.754
2013 Sohn JW, Harris LE, Berglund ED, Liu T, Vong L, Lowell BB, Balthasar N, Williams KW, Elmquist JK. Melanocortin 4 receptors reciprocally regulate sympathetic and parasympathetic preganglionic neurons. Cell. 152: 612-9. PMID 23374353 DOI: 10.1016/j.cell.2012.12.022  0.757
2013 Elmquist JK, Zigman JM, Saper CB. Mechanisms of homeostatically regulated behaviors Neuroscience in the 21st Century: From Basic to Clinical. 1753-1782. DOI: 10.1007/978-1-4614-1997-6_62  0.628
2012 Liu C, Elmquist JK. Tipping the scales early: probing the long-term effects of obesity. The Journal of Clinical Investigation. 122: 3840-2. PMID 23093788 DOI: 10.1172/Jci66409  0.304
2012 Williams KW, Elmquist JK. From neuroanatomy to behavior: central integration of peripheral signals regulating feeding behavior. Nature Neuroscience. 15: 1350-5. PMID 23007190 DOI: 10.1038/nn.3217  0.577
2012 Scott MM, Perello M, Chuang JC, Sakata I, Gautron L, Lee CE, Lauzon D, Elmquist JK, Zigman JM. Hindbrain ghrelin receptor signaling is sufficient to maintain fasting glucose. Plos One. 7: e44089. PMID 22952883 DOI: 10.1371/Journal.Pone.0044089  0.832
2012 Kim KW, Donato J, Berglund ED, Choi YH, Kohno D, Elias CF, Depinho RA, Elmquist JK. FOXO1 in the ventromedial hypothalamus regulates energy balance. The Journal of Clinical Investigation. 122: 2578-89. PMID 22653058 DOI: 10.1172/Jci62848  0.428
2012 Cui H, Sohn JW, Gautron L, Funahashi H, Williams KW, Elmquist JK, Lutter M. Neuroanatomy of melanocortin-4 receptor pathway in the lateral hypothalamic area. The Journal of Comparative Neurology. 520: 4168-83. PMID 22605619 DOI: 10.1002/cne.23145  0.731
2012 Gautron L, Lee CE, Lee S, Elmquist JK. Melanocortin-4 receptor expression in different classes of spinal and vagal primary afferent neurons in the mouse. The Journal of Comparative Neurology. 520: 3933-48. PMID 22592759 DOI: 10.1002/cne.23137  0.337
2012 Berglund ED, Vianna CR, Donato J, Kim MH, Chuang JC, Lee CE, Lauzon DA, Lin P, Brule LJ, Scott MM, Coppari R, Elmquist JK. Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice. The Journal of Clinical Investigation. 122: 1000-9. PMID 22326958 DOI: 10.1172/JCI59816  0.685
2012 Perello M, Scott MM, Sakata I, Lee CE, Chuang JC, Osborne-Lawrence S, Rovinsky SA, Elmquist JK, Zigman JM. Functional implications of limited leptin receptor and ghrelin receptor coexpression in the brain. The Journal of Comparative Neurology. 520: 281-94. PMID 21674492 DOI: 10.1002/Cne.22690  0.825
2011 Xu Y, Elmquist JK, Fukuda M. Central nervous control of energy and glucose balance: focus on the central melanocortin system. Annals of the New York Academy of Sciences. 1243: 1-14. PMID 22211889 DOI: 10.1111/J.1749-6632.2011.06248.X  0.456
2011 Xu Y, Nedungadi TP, Zhu L, Sobhani N, Irani BG, Davis KE, Zhang X, Zou F, Gent LM, Hahner LD, Khan SA, Elias CF, Elmquist JK, Clegg DJ. Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction. Cell Metabolism. 14: 453-65. PMID 21982706 DOI: 10.1016/J.Cmet.2011.08.009  0.481
2011 Williams KW, Sohn JW, Donato J, Lee CE, Zhao JJ, Elmquist JK, Elias CF. The acute effects of leptin require PI3K signaling in the hypothalamic ventral premammillary nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 13147-56. PMID 21917798 DOI: 10.1523/JNEUROSCI.2602-11.2011  0.744
2011 Sohn JW, Xu Y, Jones JE, Wickman K, Williams KW, Elmquist JK. Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels. Neuron. 71: 488-97. PMID 21835345 DOI: 10.1016/J.Neuron.2011.06.012  0.737
2011 Klöckener T, Hess S, Belgardt BF, Paeger L, Verhagen LA, Husch A, Sohn JW, Hampel B, Dhillon H, Zigman JM, Lowell BB, Williams KW, Elmquist JK, Horvath TL, Kloppenburg P, et al. High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons. Nature Neuroscience. 14: 911-8. PMID 21642975 DOI: 10.1038/Nn.2847  0.811
2011 Kim KW, Zhao L, Donato J, Kohno D, Xu Y, Elias CF, Lee C, Parker KL, Elmquist JK. Steroidogenic factor 1 directs programs regulating diet-induced thermogenesis and leptin action in the ventral medial hypothalamic nucleus. Proceedings of the National Academy of Sciences of the United States of America. 108: 10673-8. PMID 21636788 DOI: 10.1073/Pnas.1102364108  0.395
2011 Gautron L, Elmquist JK. Sixteen years and counting: an update on leptin in energy balance. The Journal of Clinical Investigation. 121: 2087-93. PMID 21633176 DOI: 10.1172/JCI45888  0.328
2011 Gautron L, Sakata I, Udit S, Zigman JM, Wood JN, Elmquist JK. Genetic tracing of Nav1.8-expressing vagal afferents in the mouse. The Journal of Comparative Neurology. 519: 3085-101. PMID 21618224 DOI: 10.1002/Cne.22667  0.729
2011 Scott MM, Williams KW, Rossi J, Lee CE, Elmquist JK. Leptin receptor expression in hindbrain Glp-1 neurons regulates food intake and energy balance in mice. The Journal of Clinical Investigation. 121: 2413-21. PMID 21606595 DOI: 10.1172/JCI43703  0.69
2011 Fukuda M, Williams KW, Gautron L, Elmquist JK. Induction of leptin resistance by activation of cAMP-Epac signaling. Cell Metabolism. 13: 331-9. PMID 21356522 DOI: 10.1016/j.cmet.2011.01.016  0.622
2011 Williams KW, Elmquist JK. Lighting up the hypothalamus: coordinated control of feeding behavior. Nature Neuroscience. 14: 277-8. PMID 21346745 DOI: 10.1038/nn0311-277  0.591
2011 Rossi J, Balthasar N, Olson D, Scott M, Berglund E, Lee CE, Choi MJ, Lauzon D, Lowell BB, Elmquist JK. Melanocortin-4 receptors expressed by cholinergic neurons regulate energy balance and glucose homeostasis. Cell Metabolism. 13: 195-204. PMID 21284986 DOI: 10.1016/J.Cmet.2011.01.010  0.425
2011 Vialou V, Cui H, Perello M, Mahgoub M, Yu HG, Rush AJ, Pranav H, Jung S, Yangisawa M, Zigman JM, Elmquist JK, Nestler EJ, Lutter M. A role for ΔFosB in calorie restriction-induced metabolic changes. Biological Psychiatry. 70: 204-7. PMID 21215388 DOI: 10.1016/J.Biopsych.2010.11.027  0.73
2011 Williams KW, Scott MM, Elmquist JK. Modulation of the central melanocortin system by leptin, insulin, and serotonin: co-ordinated actions in a dispersed neuronal network. European Journal of Pharmacology. 660: 2-12. PMID 21211525 DOI: 10.1016/j.ejphar.2010.11.042  0.635
2011 Donato J, Cravo RM, Frazão R, Gautron L, Scott MM, Lachey J, Castro IA, Margatho LO, Lee S, Lee C, Richardson JA, Friedman J, Chua S, Coppari R, Zigman JM, ... Elmquist JK, et al. Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons. The Journal of Clinical Investigation. 121: 355-68. PMID 21183787 DOI: 10.1172/Jci45106  0.672
2011 Kim KW, Sohn JW, Kohno D, Xu Y, Williams K, Elmquist JK. SF-1 in the ventral medial hypothalamic nucleus: a key regulator of homeostasis. Molecular and Cellular Endocrinology. 336: 219-23. PMID 21111025 DOI: 10.1016/J.Mce.2010.11.019  0.75
2010 Xu Y, Jones JE, Lauzon DA, Anderson JG, Balthasar N, Heisler LK, Zinn AR, Lowell BB, Elmquist JK. A serotonin and melanocortin circuit mediates D-fenfluramine anorexia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14630-4. PMID 21048120 DOI: 10.1523/Jneurosci.5412-09.2010  0.677
2010 Xu Y, Berglund ED, Sohn JW, Holland WL, Chuang JC, Fukuda M, Rossi J, Williams KW, Jones JE, Zigman JM, Lowell BB, Scherer PE, Elmquist JK. 5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver. Nature Neuroscience. 13: 1457-9. PMID 21037584 DOI: 10.1038/Nn.2664  0.801
2010 Xu Y, Hill JW, Fukuda M, Gautron L, Sohn JW, Kim KW, Lee CE, Choi MJ, Lauzon DA, Dhillon H, Lowell BB, Zigman JM, Zhao JJ, Elmquist JK. PI3K signaling in the ventromedial hypothalamic nucleus is required for normal energy homeostasis. Cell Metabolism. 12: 88-95. PMID 20620998 DOI: 10.1016/J.Cmet.2010.05.002  0.785
2010 Gautron L, Lazarus M, Scott MM, Saper CB, Elmquist JK. Identifying the efferent projections of leptin-responsive neurons in the dorsomedial hypothalamus using a novel conditional tracing approach. The Journal of Comparative Neurology. 518: 2090-108. PMID 20394060 DOI: 10.1002/cne.22323  0.543
2010 Hill JW, Elias CF, Fukuda M, Williams KW, Berglund ED, Holland WL, Cho YR, Chuang JC, Xu Y, Choi M, Lauzon D, Lee CE, Coppari R, Richardson JA, Zigman JM, ... ... Elmquist JK, et al. Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility. Cell Metabolism. 11: 286-97. PMID 20374961 DOI: 10.1016/J.Cmet.2010.03.002  0.828
2010 Williams KW, Margatho LO, Lee CE, Choi M, Lee S, Scott MM, Elias CF, Elmquist JK. Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2472-9. PMID 20164331 DOI: 10.1523/JNEUROSCI.3118-09.2010  0.649
2010 Chuang JC, Cui H, Mason BL, Mahgoub M, Bookout AL, Yu HG, Perello M, Elmquist JK, Repa JJ, Zigman JM, Lutter M. Chronic social defeat stress disrupts regulation of lipid synthesis. Journal of Lipid Research. 51: 1344-53. PMID 20129912 DOI: 10.1194/Jlr.M002196  0.737
2010 Chuang JC, Krishnan V, Yu HG, Mason B, Cui H, Cui H, Wilkinson MB, Zigman JM, Elmquist JK, Nestler EJ, Lutter M. A beta3-adrenergic-leptin-melanocortin circuit regulates behavioral and metabolic changes induced by chronic stress. Biological Psychiatry. 67: 1075-82. PMID 20060958 DOI: 10.1016/J.Biopsych.2009.12.003  0.712
2010 Gautron L, Lee C, Funahashi H, Friedman J, Lee S, Elmquist J. Melanocortin-4 receptor expression in a vago-vagal circuitry involved in postprandial functions. The Journal of Comparative Neurology. 518: 6-24. PMID 19882715 DOI: 10.1002/Cne.22221  0.352
2010 Hill JW, Burgess A, Bruning JC, Lowell BB, Elmquist JK, Abraham NG. The Metabolic Syndrome and Ovarian Dysfunction in Mice. Biology of Reproduction. 83: 588-588. DOI: 10.1093/Biolreprod/83.S1.588  0.452
2009 Lutter M, Elmquist J. Depression and metabolism: linking changes in leptin and ghrelin to mood. F1000 Biology Reports. 1: 63. PMID 20948621 DOI: 10.3410/B1-63  0.333
2009 Ramadori G, Gautron L, Fujikawa T, Vianna CR, Elmquist JK, Coppari R. Central administration of resveratrol improves diet-induced diabetes. Endocrinology. 150: 5326-33. PMID 19819963 DOI: 10.1210/En.2009-0528  0.575
2009 Hill JW, Xu Y, Preitner F, Fukuda M, Cho YR, Luo J, Balthasar N, Coppari R, Cantley LC, Kahn BB, Zhao JJ, Elmquist JK. Phosphatidyl inositol 3-kinase signaling in hypothalamic proopiomelanocortin neurons contributes to the regulation of glucose homeostasis. Endocrinology. 150: 4874-82. PMID 19819947 DOI: 10.1210/En.2009-0454  0.675
2009 Sakata I, Yang J, Lee CE, Osborne-Lawrence S, Rovinsky SA, Elmquist JK, Zigman JM. Colocalization of ghrelin O-acyltransferase and ghrelin in gastric mucosal cells. American Journal of Physiology. Endocrinology and Metabolism. 297: E134-41. PMID 19401456 DOI: 10.1152/Ajpendo.90859.2008  0.668
2009 Sakata I, Nakano Y, Osborne-Lawrence S, Rovinsky SA, Lee CE, Perello M, Anderson JG, Coppari R, Xiao G, Lowell BB, Elmquist JK, Zigman JM. Characterization of a novel ghrelin cell reporter mouse. Regulatory Peptides. 155: 91-8. PMID 19361544 DOI: 10.1016/J.Regpep.2009.04.001  0.763
2009 Scott MM, Lachey JL, Sternson SM, Lee CE, Elias CF, Friedman JM, Elmquist JK. Leptin targets in the mouse brain. The Journal of Comparative Neurology. 514: 518-32. PMID 19350671 DOI: 10.1002/Cne.22025  0.387
2009 Coppari R, Ramadori G, Elmquist JK. The role of transcriptional regulators in central control of appetite and body weight. Nature Clinical Practice. Endocrinology & Metabolism. 5: 160-6. PMID 19229236 DOI: 10.1038/ncpendmet1070  0.321
2009 Williams KW, Scott MM, Elmquist JK. From observation to experimentation: leptin action in the mediobasal hypothalamus. The American Journal of Clinical Nutrition. 89: 985S-990S. PMID 19176744 DOI: 10.3945/ajcn.2008.26788D  0.646
2008 Tong Q, Ye CP, Jones JE, Elmquist JK, Lowell BB. Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance. Nature Neuroscience. 11: 998-1000. PMID 19160495 DOI: 10.1038/nn.2167  0.31
2008 Fukuda M, Jones JE, Olson D, Hill J, Lee CE, Gautron L, Choi M, Zigman JM, Lowell BB, Elmquist JK. Monitoring FoxO1 localization in chemically identified neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13640-8. PMID 19074037 DOI: 10.1523/Jneurosci.4023-08.2008  0.749
2008 Xu Y, Jones JE, Kohno D, Williams KW, Lee CE, Choi MJ, Anderson JG, Heisler LK, Zigman JM, Lowell BB, Elmquist JK. 5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis. Neuron. 60: 582-9. PMID 19038216 DOI: 10.1016/J.Neuron.2008.09.033  0.825
2008 Ramadori G, Lee CE, Bookout AL, Lee S, Williams KW, Anderson J, Elmquist JK, Coppari R. Brain SIRT1: anatomical distribution and regulation by energy availability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 9989-96. PMID 18829956 DOI: 10.1523/JNEUROSCI.3257-08.2008  0.638
2008 Lutter M, Sakata I, Osborne-Lawrence S, Rovinsky SA, Anderson JG, Jung S, Birnbaum S, Yanagisawa M, Elmquist JK, Nestler EJ, Zigman JM. The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress. Nature Neuroscience. 11: 752-3. PMID 18552842 DOI: 10.1038/Nn.2139  0.65
2008 Hill JW, Williams KW, Ye C, Luo J, Balthasar N, Coppari R, Cowley MA, Cantley LC, Lowell BB, Elmquist JK. Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice. The Journal of Clinical Investigation. 118: 1796-805. PMID 18382766 DOI: 10.1172/Jci32964  0.758
2008 Hill JW, Elmquist JK, Elias CF. Hypothalamic pathways linking energy balance and reproduction. American Journal of Physiology. Endocrinology and Metabolism. 294: E827-32. PMID 18285524 DOI: 10.1152/Ajpendo.00670.2007  0.554
2008 van de Wall E, Leshan R, Xu AW, Balthasar N, Coppari R, Liu SM, Jo YH, MacKenzie RG, Allison DB, Dun NJ, Elmquist J, Lowell BB, Barsh GS, de Luca C, Myers MG, et al. Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion. Endocrinology. 149: 1773-85. PMID 18162515 DOI: 10.1210/En.2007-1132  0.538
2007 Zhou L, Sutton GM, Rochford JJ, Semple RK, Lam DD, Oksanen LJ, Thornton-Jones ZD, Clifton PG, Yueh CY, Evans ML, McCrimmon RJ, Elmquist JK, Butler AA, Heisler LK. Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways. Cell Metabolism. 6: 398-405. PMID 17983585 DOI: 10.1016/J.Cmet.2007.10.008  0.751
2007 Morioka T, Asilmaz E, Hu J, Dishinger JF, Kurpad AJ, Elias CF, Li H, Elmquist JK, Kennedy RT, Kulkarni RN. Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice. The Journal of Clinical Investigation. 117: 2860-8. PMID 17909627 DOI: 10.1172/Jci30910  0.307
2007 Parton LE, Ye CP, Coppari R, Enriori PJ, Choi B, Zhang CY, Xu C, Vianna CR, Balthasar N, Lee CE, Elmquist JK, Cowley MA, Lowell BB. Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity. Nature. 449: 228-32. PMID 17728716 DOI: 10.1038/nature06098  0.342
2007 Williams KW, Coppari R, Elmquist JK. "AMPing up" our understanding of the hypothalamic control of energy balance. The Journal of Clinical Investigation. 117: 2089-92. PMID 17671647 DOI: 10.1172/JCI32975  0.623
2007 Heisler LK, Pronchuk N, Nonogaki K, Zhou L, Raber J, Tung L, Yeo GS, O'Rahilly S, Colmers WF, Elmquist JK, Tecott LH. Serotonin activates the hypothalamic-pituitary-adrenal axis via serotonin 2C receptor stimulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 6956-64. PMID 17596444 DOI: 10.1523/Jneurosci.2584-06.2007  0.73
2007 Inagaki T, Dutchak P, Zhao G, Ding X, Gautron L, Parameswara V, Li Y, Goetz R, Mohammadi M, Esser V, Elmquist JK, Gerard RD, Burgess SC, Hammer RE, Mangelsdorf DJ, et al. Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21. Cell Metabolism. 5: 415-25. PMID 17550777 DOI: 10.1016/J.Cmet.2007.05.003  0.53
2007 Tong Q, Ye C, McCrimmon RJ, Dhillon H, Choi B, Kramer MD, Yu J, Yang Z, Christiansen LM, Lee CE, Choi CS, Zigman JM, Shulman GI, Sherwin RS, Elmquist JK, et al. Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia. Cell Metabolism. 5: 383-93. PMID 17488640 DOI: 10.1016/J.Cmet.2007.04.001  0.645
2007 Münzberg H, Jobst EE, Bates SH, Jones J, Villanueva E, Leshan R, Björnholm M, Elmquist J, Sleeman M, Cowley MA, Myers MG. Appropriate inhibition of orexigenic hypothalamic arcuate nucleus neurons independently of leptin receptor/STAT3 signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 69-74. PMID 17202473 DOI: 10.1523/JNEUROSCI.3168-06.2007  0.394
2006 Zigman JM, Elmquist JK. In search of an effective obesity treatment: a shot in the dark or a shot in the arm? Proceedings of the National Academy of Sciences of the United States of America. 103: 12961-2. PMID 16924097 DOI: 10.1073/Pnas.0605959103  0.549
2006 Kievit P, Howard JK, Badman MK, Balthasar N, Coppari R, Mori H, Lee CE, Elmquist JK, Yoshimura A, Flier JS. Enhanced leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells. Cell Metabolism. 4: 123-32. PMID 16890540 DOI: 10.1016/j.cmet.2006.06.010  0.403
2006 Heisler LK, Jobst EE, Sutton GM, Zhou L, Borok E, Thornton-Jones Z, Liu HY, Zigman JM, Balthasar N, Kishi T, Lee CE, Aschkenasi CJ, Zhang CY, Yu J, Boss O, ... ... Elmquist JK, et al. Serotonin reciprocally regulates melanocortin neurons to modulate food intake. Neuron. 51: 239-49. PMID 16846858 DOI: 10.1016/J.Neuron.2006.06.004  0.773
2006 Elmquist J, Zigman J, Lutter M. Molecular determinants of energy homeostasis. The American Journal of Psychiatry. 163: 1137. PMID 16816215 DOI: 10.1176/Appi.Ajp.163.7.1137  0.636
2006 Scott MM, Marcus JN, Elmquist JK. Orexin neurons and the TASK of glucosensing. Neuron. 50: 665-7. PMID 16731504 DOI: 10.1016/J.Neuron.2006.05.014  0.311
2006 Dhillon H, Zigman JM, Ye C, Lee CE, McGovern RA, Tang V, Kenny CD, Christiansen LM, White RD, Edelstein EA, Coppari R, Balthasar N, Cowley MA, Chua S, Elmquist JK, et al. Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis. Neuron. 49: 191-203. PMID 16423694 DOI: 10.1016/J.Neuron.2005.12.021  0.715
2006 Zigman JM, Jones JE, Lee CE, Saper CB, Elmquist JK. Expression of ghrelin receptor mRNA in the rat and the mouse brain. The Journal of Comparative Neurology. 494: 528-48. PMID 16320257 DOI: 10.1002/Cne.21171  0.704
2005 Zigman JM, Nakano Y, Coppari R, Balthasar N, Marcus JN, Lee CE, Jones JE, Deysher AE, Waxman AR, White RD, Williams TD, Lachey JL, Seeley RJ, Lowell BB, Elmquist JK. Mice lacking ghrelin receptors resist the development of diet-induced obesity. The Journal of Clinical Investigation. 115: 3564-72. PMID 16322794 DOI: 10.1172/Jci26002  0.663
2005 Coppari R, Ichinose M, Lee CE, Pullen AE, Kenny CD, McGovern RA, Tang V, Liu SM, Ludwig T, Chua SC, Lowell BB, Elmquist JK. The hypothalamic arcuate nucleus: a key site for mediating leptin's effects on glucose homeostasis and locomotor activity. Cell Metabolism. 1: 63-72. PMID 16054045 DOI: 10.1016/J.Cmet.2004.12.004  0.344
2004 Balthasar N, Coppari R, McMinn J, Liu SM, Lee CE, Tang V, Kenny CD, McGovern RA, Chua SC, Elmquist JK, Lowell BB. Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis. Neuron. 42: 983-91. PMID 15207242 DOI: 10.1016/j.neuron.2004.06.004  0.453
2004 Kelly JF, Elias CF, Lee CE, Ahima RS, Seeley RJ, Bjørbaek C, Oka T, Saper CB, Flier JS, Elmquist JK. Ciliary neurotrophic factor and leptin induce distinct patterns of immediate early gene expression in the brain. Diabetes. 53: 911-20. PMID 15047605 DOI: 10.2337/Diabetes.53.4.911  0.496
2003 Zigman JM, Elmquist JK. Minireview: From anorexia to obesity--the yin and yang of body weight control. Endocrinology. 144: 3749-56. PMID 12933644 DOI: 10.1210/En.2003-0241  0.61
2003 Heisler LK, Cowley MA, Kishi T, Tecott LH, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro J, Zigman JM, Cone RD, Elmquist JK. Central serotonin and melanocortin pathways regulating energy homeostasis. Annals of the New York Academy of Sciences. 994: 169-74. PMID 12851313 DOI: 10.1111/J.1749-6632.2003.Tb03177.X  0.806
2003 Zhang YH, Lu J, Elmquist JK, Saper CB. Specific roles of cyclooxygenase-1 and cyclooxygenase-2 in lipopolysaccharide-induced fever and Fos expression in rat brain. The Journal of Comparative Neurology. 463: 3-12. PMID 12811798 DOI: 10.1002/Cne.10743  0.426
2003 Yamamoto H, Kishi T, Lee CE, Choi BJ, Fang H, Hollenberg AN, Drucker DJ, Elmquist JK. Glucagon-like peptide-1-responsive catecholamine neurons in the area postrema link peripheral glucagon-like peptide-1 with central autonomic control sites. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2939-46. PMID 12684481  0.304
2003 Kishi T, Aschkenasi CJ, Lee CE, Mountjoy KG, Saper CB, Elmquist JK. Expression of melanocortin 4 receptor mRNA in the central nervous system of the rat. The Journal of Comparative Neurology. 457: 213-35. PMID 12541307 DOI: 10.1002/cne.10454  0.491
2002 Saper CB, Chou TC, Elmquist JK. The need to feed: homeostatic and hedonic control of eating. Neuron. 36: 199-211. PMID 12383777 DOI: 10.1016/S0896-6273(02)00969-8  0.46
2002 Hahm S, Fekete C, Mizuno TM, Windsor J, Yan H, Boozer CN, Lee C, Elmquist JK, Lechan RM, Mobbs CV, Salton SR. VGF is required for obesity induced by diet, gold thioglucose treatment, and agouti and is differentially regulated in pro-opiomelanocortin- and neuropeptide Y-containing arcuate neurons in response to fasting. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6929-38. PMID 12177191 DOI: 10.1523/Jneurosci.22-16-06929.2002  0.386
2002 Heisler LK, Cowley MA, Tecott LH, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro JB, Marcus JN, Holstege H, Lee CE, Cone RD, Elmquist JK. Activation of central melanocortin pathways by fenfluramine. Science (New York, N.Y.). 297: 609-11. PMID 12142539 DOI: 10.1126/Science.1072327  0.723
2002 Yamamoto H, Lee CE, Marcus JN, Williams TD, Overton JM, Lopez ME, Hollenberg AN, Baggio L, Saper CB, Drucker DJ, Elmquist JK. Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons. The Journal of Clinical Investigation. 110: 43-52. PMID 12093887 DOI: 10.1172/Jci15595  0.544
2002 Zabolotny JM, Bence-Hanulec KK, Stricker-Krongrad A, Haj F, Wang Y, Minokoshi Y, Kim YB, Elmquist JK, Tartaglia LA, Kahn BB, Neel BG. PTP1B regulates leptin signal transduction in vivo. Developmental Cell. 2: 489-95. PMID 11970898 DOI: 10.1016/S1534-5807(02)00148-X  0.352
2001 Elmquist JK. Hypothalamic pathways underlying the endocrine, autonomic, and behavioral effects of leptin. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity. 25: S78-82. PMID 11840221 DOI: 10.1038/sj.ijo.0801918  0.517
2001 Elmquist JK. Hypothalamic pathways underlying the endocrine, autonomic, and behavioral effects of leptin. Physiology & Behavior. 74: 703-8. PMID 11790432 DOI: 10.1016/S0031-9384(01)00613-8  0.438
2001 Chou TC, Lee CE, Lu J, Elmquist JK, Hara J, Willie JT, Beuckmann CT, Chemelli RM, Sakurai T, Yanagisawa M, Saper CB, Scammell TE. Orexin (hypocretin) neurons contain dynorphin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: RC168. PMID 11567079 DOI: 10.1523/Jneurosci.21-19-J0003.2001  0.575
2001 Malick A, Jakubowski M, Elmquist JK, Saper CB, Burstein R. A neurohistochemical blueprint for pain-induced loss of appetite. Proceedings of the National Academy of Sciences of the United States of America. 98: 9930-5. PMID 11504950 DOI: 10.1073/Pnas.171616898  0.526
2001 Lu J, Zhang YH, Chou TC, Gaus SE, Elmquist JK, Shiromani P, Saper CB. Contrasting effects of ibotenate lesions of the paraventricular nucleus and subparaventricular zone on sleep-wake cycle and temperature regulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 4864-74. PMID 11425913 DOI: 10.1523/Jneurosci.21-13-04864.2001  0.41
2001 Marcus JN, Aschkenasi CJ, Lee CE, Chemelli RM, Saper CB, Yanagisawa M, Elmquist JK. Differential expression of orexin receptors 1 and 2 in the rat brain. The Journal of Comparative Neurology. 435: 6-25. PMID 11370008 DOI: 10.1002/cne.1190  0.497
2001 Elias CF, Lee CE, Kelly JF, Ahima RS, Kuhar M, Saper CB, Elmquist JK. Characterization of CART neurons in the rat and human hypothalamus. The Journal of Comparative Neurology. 432: 1-19. PMID 11241374 DOI: 10.1002/Cne.1085  0.577
2001 Ludwig DS, Tritos NA, Mastaitis JW, Kulkarni R, Kokkotou E, Elmquist J, Lowell B, Flier JS, Maratos-Flier E. Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance. The Journal of Clinical Investigation. 107: 379-86. PMID 11160162 DOI: 10.1172/Jci10660  0.415
2000 Oka T, Oka K, Scammell TE, Lee C, Kelly JF, Nantel F, Elmquist JK, Saper CB. Relationship of EP(1-4) prostaglandin receptors with rat hypothalamic cell groups involved in lipopolysaccharide fever responses. The Journal of Comparative Neurology. 428: 20-32. PMID 11058222 DOI: 10.1002/1096-9861(20001204)428:1<20::AID-CNE3>3.0.CO;2-X  0.498
2000 Zhang YH, Lu J, Elmquist JK, Saper CB. Lipopolysaccharide activates specific populations of hypothalamic and brainstem neurons that project to the spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 6578-86. PMID 10964963 DOI: 10.1523/Jneurosci.20-17-06578.2000  0.505
2000 Ahima RS, Saper CB, Flier JS, Elmquist JK. Leptin regulation of neuroendocrine systems. Frontiers in Neuroendocrinology. 21: 263-307. PMID 10882542 DOI: 10.1006/Frne.2000.0197  0.572
2000 Elias CF, Kelly JF, Lee CE, Ahima RS, Drucker DJ, Saper CB, Elmquist JK. Chemical characterization of leptin-activated neurons in the rat brain. The Journal of Comparative Neurology. 423: 261-81. PMID 10867658 DOI: 10.1002/1096-9861(20000724)423:2<261::Aid-Cne6>3.0.Co;2-6  0.584
2000 Silveira DC, Klein P, Ransil BJ, Liu Z, Hori A, Holmes GL, de LaCalle S, Elmquist J, Herzog AG. Lateral asymmetry in activation of hypothalamic neurons with unilateral amygdaloid seizures. Epilepsia. 41: 34-41. PMID 10643921 DOI: 10.1111/J.1528-1157.2000.Tb01502.X  0.72
1999 Ahima RS, Kelly J, Elmquist JK, Flier JS. Distinct Physiologic and Neuronal Responses to Decreased Leptin and Mild Hyperleptinemia1. Endocrinology. 140: 4923-4931. PMID 28200577 DOI: 10.1210/endo.140.11.7105  0.357
1999 Ahima RS, Kelly J, Elmquist JK, Flier JS. Distinct physiologic and neuronal responses to decreased leptin and mild hyperleptinemia. Endocrinology. 140: 4923-31. PMID 10537115 DOI: 10.1210/Endo.140.11.7105  0.362
1999 Elias CF, Aschkenasi C, Lee C, Kelly J, Ahima RS, Bjorbaek C, Flier JS, Saper CB, Elmquist JK. Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area. Neuron. 23: 775-86. PMID 10482243 DOI: 10.1016/S0896-6273(01)80035-0  0.595
1999 Chemelli RM, Willie JT, Sinton CM, Elmquist JK, Scammell T, Lee C, Richardson JA, Williams SC, Xiong Y, Kisanuki Y, Fitch TE, Nakazato M, Hammer RE, Saper CB, Yanagisawa M. Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell. 98: 437-51. PMID 10481909 DOI: 10.1016/S0092-8674(00)81973-X  0.454
1999 Elmquist JK, Elias CF, Saper CB. From lesions to leptin: hypothalamic control of food intake and body weight. Neuron. 22: 221-32. PMID 10069329 DOI: 10.1016/S0896-6273(00)81084-3  0.541
1998 Scammell TE, Griffin JD, Elmquist JK, Saper CB. Microinjection of a cyclooxygenase inhibitor into the anteroventral preoptic region attenuates LPS fever. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 274: R783-R789. PMID 29586927 DOI: 10.1152/ajpregu.1998.274.3.R783  0.377
1998 Elmquist JK, Maratos-Flier E, Saper CB, Flier JS. Unraveling the central nervous system pathways underlying responses to leptin. Nature Neuroscience. 1: 445-50. PMID 10196541 DOI: 10.1038/2164  0.592
1998 Elias CF, Lee C, Kelly J, Aschkenasi C, Ahima RS, Couceyro PR, Kuhar MJ, Saper CB, Elmquist JK. Leptin activates hypothalamic CART neurons projecting to the spinal cord. Neuron. 21: 1375-85. PMID 9883730 DOI: 10.1016/S0896-6273(00)80656-X  0.559
1998 Elias CF, Saper CB, Maratos-Flier E, Tritos NA, Lee C, Kelly J, Tatro JB, Hoffman GE, Ollmann MM, Barsh GS, Sakurai T, Yanagisawa M, Elmquist JK. Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area. The Journal of Comparative Neurology. 402: 442-59. PMID 9862320 DOI: 10.1002/(Sici)1096-9861(19981228)402:4<442::Aid-Cne2>3.0.Co;2-R  0.566
1998 Tritos NA, Elmquist JK, Mastaitis JW, Flier JS, Maratos-Flier E. Characterization of expression of hypothalamic appetite-regulating peptides in obese hyperleptinemic brown adipose tissue-deficient (uncoupling protein-promoter-driven diphtheria toxin A) mice. Endocrinology. 139: 4634-41. PMID 9794475 DOI: 10.1210/Endo.139.11.6308  0.31
1998 Bjørbaek C, Elmquist JK, Frantz JD, Shoelson SE, Flier JS. Identification of SOCS-3 as a potential mediator of central leptin resistance. Molecular Cell. 1: 619-25. PMID 9660946 DOI: 10.1016/S1097-2765(00)80062-3  0.307
1998 Elmquist JK, Bjørbaek C, Ahima RS, Flier JS, Saper CB. Distributions of leptin receptor mRNA isoforms in the rat brain. The Journal of Comparative Neurology. 395: 535-47. PMID 9619505 DOI: 10.1002/(Sici)1096-9861(19980615)395:4<535::Aid-Cne9>3.0.Co;2-2  0.487
1998 Sherin JE, Elmquist JK, Torrealba F, Saper CB. Innervation of histaminergic tuberomammillary neurons by GABAergic and galaninergic neurons in the ventrolateral preoptic nucleus of the rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 4705-21. PMID 9614245 DOI: 10.1523/Jneurosci.18-12-04705.1998  0.496
1998 Scammell TE, Griffin JD, Elmquist JK, Saper CB. Microinjection of a cyclooxygenase inhibitor into the anteroventral preoptic region attenuates LPS fever. The American Journal of Physiology. 274: R783-9. PMID 9530246 DOI: 10.1152/Ajpregu.1998.274.3.R783  0.378
1998 Elmquist JK, Ahima RS, Elias CF, Flier JS, Saper CB. Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei. Proceedings of the National Academy of Sciences of the United States of America. 95: 741-6. PMID 9435263 DOI: 10.1073/Pnas.95.2.741  0.526
1997 Elmquist JK, Scammell TE, Saper CB. Mechanisms of CNS response to systemic immune challenge: the febrile response. Trends in Neurosciences. 20: 565-70. PMID 9416669 DOI: 10.1016/S0166-2236(97)01138-7  0.419
1997 Elmquist JK, Breder CD, Sherin JE, Scammell TE, Hickey WF, Dewitt D, Saper CB. Intravenous lipopolysaccharide induces cyclooxygenase 2-like immunoreactivity in rat brain perivascular microglia and meningeal macrophages. The Journal of Comparative Neurology. 381: 119-29. PMID 9130663 DOI: 10.1002/(SICI)1096-9861(19970505)381:2<119::AID-CNE1>3.0.CO;2-6  0.715
1997 Elmquist JK, Ahima RS, Maratos-Flier E, Flier JS, Saper CB. Leptin activates neurons in ventrobasal hypothalamus and brainstem. Endocrinology. 138: 839-42. PMID 9003024 DOI: 10.1210/Endo.138.2.5033  0.573
1996 Elmquist JK, Saper CB. Activation of neurons projecting to the paraventricular hypothalamic nucleus by intravenous lipopolysaccharide. The Journal of Comparative Neurology. 374: 315-31. PMID 8906501 DOI: 10.1002/(SICI)1096-9861(19961021)374:3<315::AID-CNE1>3.0.CO;2-4  0.492
1996 Elmquist JK, Scammell TE, Jacobson CD, Saper CB. Distribution of Fos-like immunoreactivity in the rat brain following intravenous lipopolysaccharide administration. The Journal of Comparative Neurology. 371: 85-103. PMID 8835720 DOI: 10.1002/(SICI)1096-9861(19960715)371:1<85::AID-CNE5>3.0.CO;2-H  0.435
1996 Scammell TE, Elmquist JK, Griffin JD, Saper CB. Ventromedial preoptic prostaglandin E2 activates fever-producing autonomic pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 6246-54. PMID 8815905 DOI: 10.1523/Jneurosci.16-19-06246.1996  0.445
1996 Scammell TE, Elmquist JK, Saper CB. Inhibition of nitric oxide synthase produces hypothermia and depresses lipopolysaccharide fever. The American Journal of Physiology. 271: R333-8. PMID 8770131 DOI: 10.1152/Ajpregu.1996.271.2.R333  0.388
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