Sandra Hewett, Ph.D. - Publications

Biology Syracuse University, Syracuse, NY, United States 
Interplay between Excitotoxicity and Inflammation

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Sears SMS, Roberts SH, Hewett SJ. Hyperexcitability and brain morphological differences in mice lacking the cystine/glutamate antiporter, system x. Journal of Neuroscience Research. 99: 3339-3353. PMID 34747522 DOI: 10.1002/jnr.24971  0.756
2021 Sears SM, Hewett SJ. Influence of glutamate and GABA transport on brain excitatory/inhibitory balance. Experimental Biology and Medicine (Maywood, N.J.). 1535370221989263. PMID 33554649 DOI: 10.1177/1535370221989263  0.734
2020 Sosnoski HM, Sears SMS, He Y, Frare C, Hewett SJ. Sexually dimorphic and brain region-specific transporter adaptations in system x null mice. Neurochemistry International. 141: 104888. PMID 33199267 DOI: 10.1016/j.neuint.2020.104888  0.744
2019 Sears SMS, Hewett JA, Hewett SJ. Decreased epileptogenesis in mice lacking the System x transporter occurs in association with a reduction in AMPA receptor subunit GluA1. Epilepsia Open. 4: 133-143. PMID 30868123 DOI: 10.1002/epi4.12307  0.737
2018 Kanzler MA, Van Dyke AM, He Y, Hewett JA, Hewett SJ. Mice lacking L-12/15-lipoxygenase show increased mortality during kindling despite demonstrating resistance to epileptogenesis. Epilepsia Open. 3: 255-263. PMID 29881804 DOI: 10.1002/epi4.12221  0.744
2015 Thorn TL, He Y, Jackman NA, Lobner D, Hewett JA, Hewett SJ. A Cytotoxic, Co-operative Interaction Between Energy Deprivation and Glutamate Release From System xc- Mediates Aglycemic Neuronal Cell Death. Asn Neuro. 7. PMID 26553727 DOI: 10.1177/1759091415614301  0.669
2015 Massie A, Boillée S, Hewett S, Knackstedt L, Lewerenz J. Main path and byways: non-vesicular glutamate release by system xc (-) as an important modifier of glutamatergic neurotransmission. Journal of Neurochemistry. PMID 26336934 DOI: 10.1111/Jnc.13348  0.404
2012 Jackman NA, Melchior SE, Hewett JA, Hewett SJ. Non-cell autonomous influence of the astrocyte system xc- on hypoglycaemic neuronal cell death. Asn Neuro. 4. PMID 22220511 DOI: 10.1042/AN20110030  0.302
2012 Uliasz TF, Hamby ME, Jackman NA, Hewett JA, Hewett SJ. Generation of primary astrocyte cultures devoid of contaminating microglia. Methods in Molecular Biology (Clifton, N.J.). 814: 61-79. PMID 22144300 DOI: 10.1007/978-1-61779-452-0_5  0.742
2011 Sen E, Basu A, Willing LB, Uliasz TF, Myrkalo JL, Vannucci SJ, Hewett SJ, Levison SW. Pre-conditioning induces the precocious differentiation of neonatal astrocytes to enhance their neuroprotective properties. Asn Neuro. 3: e00062. PMID 21722095 DOI: 10.1042/An20100029  0.313
2010 Jackman NA, Uliasz TF, Hewett JA, Hewett SJ. Regulation of system x(c)(-)activity and expression in astrocytes by interleukin-1β: implications for hypoxic neuronal injury. Glia. 58: 1806-15. PMID 20645408 DOI: 10.1002/glia.21050  0.321
2010 Hamby ME, Hewett JA, Hewett SJ. Smad3-dependent signaling underlies the TGF-β1-mediated enhancement in astrocytic iNOS expression. Glia. 58: 1282-91. PMID 20607716 DOI: 10.1002/glia.21005  0.764
2008 Fogal B, Hewett SJ. Interleukin-1beta: a bridge between inflammation and excitotoxicity? Journal of Neurochemistry. 106: 1-23. PMID 18315560 DOI: 10.1111/j.1471-4159.2008.05315.x  0.768
2008 Hamby ME, Hewett JA, Hewett SJ. TGF-beta1 reduces the heterogeneity of astrocytic cyclooxygenase-2 and nitric oxide synthase-2 gene expression in a stimulus-independent manner. Prostaglandins & Other Lipid Mediators. 85: 115-24. PMID 18194875 DOI: 10.1016/j.prostaglandins.2007.11.004  0.757
2008 Hamby ME, Gragnolati AR, Hewett SJ, Hewett JA. TGF beta 1 and TNF alpha potentiate nitric oxide production in astrocyte cultures by recruiting distinct subpopulations of cells to express NOS-2. Neurochemistry International. 52: 962-71. PMID 18035449 DOI: 10.1016/j.neuint.2007.10.010  0.761
2007 Fogal B, Li J, Lobner D, McCullough LD, Hewett SJ. System x(c)- activity and astrocytes are necessary for interleukin-1 beta-mediated hypoxic neuronal injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10094-105. PMID 17881516 DOI: 10.1523/Jneurosci.2459-07.2007  0.769
2006 Hamby ME, Hewett JA, Hewett SJ. TGF-beta1 potentiates astrocytic nitric oxide production by expanding the population of astrocytes that express NOS-2. Glia. 54: 566-77. PMID 16921522 DOI: 10.1002/glia.20411  0.757
2006 Hamby ME, Uliasz TF, Hewett SJ, Hewett JA. Characterization of an improved procedure for the removal of microglia from confluent monolayers of primary astrocytes. Journal of Neuroscience Methods. 150: 128-37. PMID 16105687 DOI: 10.1016/j.jneumeth.2005.06.016  0.75
2005 Fogal B, Hewett JA, Hewett SJ. Interleukin-1beta potentiates neuronal injury in a variety of injury models involving energy deprivation. Journal of Neuroimmunology. 161: 93-100. PMID 15748948 DOI: 10.1016/j.jneuroim.2004.12.007  0.773
2004 Vidwans AS, Hewett SJ. Enhanced release of synaptic glutamate underlies the potentiation of oxygen-glucose deprivation-induced neuronal injury after induction of NOS-2. Experimental Neurology. 190: 91-101. PMID 15473983 DOI: 10.1016/j.expneurol.2004.06.018  0.316
1998 Xu YF, Hewett SJ, Atchison WD. Passive transfer of Lambert-Eaton myasthenic syndrome induces dihydropyridine sensitivity of ICa in mouse motor nerve terminals. Journal of Neurophysiology. 80: 1056-69. PMID 9744921 DOI: 10.1152/Jn.1998.80.3.1056  0.528
1996 Hewett SJ, Muir JK, Lobner D, Symons A, Choi DW. Potentiation of oxygen-glucose deprivation-induced neuronal death after induction of iNOS. Stroke; a Journal of Cerebral Circulation. 27: 1586-91. PMID 8784134 DOI: 10.1161/01.Str.27.9.1586  0.732
1996 Hewett SJ, Misko TP, Keeling RM, Behrens MM, Choi DW, Cross AH. Murine encephalitogenic lymphoid cells induce nitric oxide synthase in primary astrocytes. Journal of Neuroimmunology. 64: 201-8. PMID 8632063 DOI: 10.1016/0165-5728(95)00178-6  0.47
1995 Hewett SJ, Choi DW, Gutmann DH. Expression of the neurofibromatosis 1 (NF1) gene in reactive astrocytes in vitro. Neuroreport. 6: 1565-8. PMID 7579150 DOI: 10.1097/00001756-199507310-00025  0.479
1994 Hewett SJ, Csernansky CA, Choi DW. Selective potentiation of NMDA-induced neuronal injury following induction of astrocytic iNOS. Neuron. 13: 487-94. PMID 7520256 DOI: 10.1016/0896-6273(94)90362-X  0.49
1993 Hewett SJ, Corbett JA, McDaniel ML, Choi DW. Inhibition of nitric oxide formation does not protect murine cortical cell cultures from N-methyl-D-aspartate neurotoxicity. Brain Research. 625: 337-41. PMID 8275317 DOI: 10.1016/0006-8993(93)91078-7  0.466
1993 Hewett SJ, Corbett JA, McDaniel ML, Choi DW. Interferon-gamma and interleukin-1 beta induce nitric oxide formation from primary mouse astrocytes. Neuroscience Letters. 164: 229-32. PMID 7512249 DOI: 10.1016/0304-3940(93)90898-U  0.476
1992 Hewett SJ, Atchison WD. Specificity of Lambert-Eaton myasthenic syndrome immunoglobulin for nerve terminal calcium channels. Brain Research. 599: 324-32. PMID 1363289 DOI: 10.1016/0006-8993(92)90408-2  0.53
1992 Hewett SJ, Atchison WD. Disruption of synaptosomal calcium channel function by Lambert-Eaton myasthenic immunoglobulin is serum-dependent. Brain Research. 599: 317-23. PMID 1363288 DOI: 10.1016/0006-8993(92)90407-Z  0.516
1992 Hewett SJ, Atchison WD. Effects of charge and lipophilicity on mercurial-induced reduction of 45Ca2+ uptake in isolated nerve terminals of the rat. Toxicology and Applied Pharmacology. 113: 267-73. PMID 1313995 DOI: 10.1016/0041-008X(92)90124-B  0.517
1991 Hewett SJ, Atchison WD. Serum and plasma from patients with Lambert-Eaton Myasthenic Syndrome reduce depolarization-dependent uptake of 45Ca2+ into rat cortical synaptosomes. Brain Research. 566: 320-4. PMID 1814548 DOI: 10.1016/0006-8993(91)91717-F  0.525
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