| Year |
Citation |
Score |
| 2024 |
Sun ZC, Han WJ, Dou ZW, Lu N, Wang X, Wang FD, Ma SB, Tian ZC, Xian H, Liu WN, Liu YY, Wu WB, Chu WG, Guo H, Wang F, ... ... Freichel M, et al. TRPC3/6 Channels Mediate Mechanical Pain Hypersensitivity via Enhancement of Nociceptor Excitability and of Spinal Synaptic Transmission. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2404342. PMID 39340833 DOI: 10.1002/advs.202404342 |
0.338 |
|
| 2024 |
Freichel M, Tsvilovskyy V, Philippaert K, Schulte U, Ottenheijm R. The many facets of TMEM63/OCaR proteins as mechanosensitive channels in lysosomes, NAADP signaling and beyond. Cell Calcium. 123: 102942. PMID 39121527 DOI: 10.1016/j.ceca.2024.102942 |
0.326 |
|
| 2023 |
Freichel M, Tsvilovskyy V, Philippaert K. Resolving the heteromeric composition and macromolecular environment of TRPC channels in the brain. Cell Calcium. 111: 102714. PMID 36921407 DOI: 10.1016/j.ceca.2023.102714 |
0.317 |
|
| 2022 |
Yarishkin O, Phuong TTT, Vazquez-Chona F, Bertrand J, van Battenburg-Sherwood J, Redmon SN, Rudzitis CN, Lakk M, Baumann JM, Freichel M, Hwang EM, Overby D, Križaj D. Emergent Temporal Signaling in Human Trabecular Meshwork Cells: Role of TRPV4-TRPM4 Interactions. Frontiers in Immunology. 13: 805076. PMID 35432302 DOI: 10.3389/fimmu.2022.805076 |
0.324 |
|
| 2020 |
Jeon J, Bu F, Sun G, Tian JB, Ting SM, Li J, Aronowski J, Birnbaumer L, Freichel M, Zhu MX. Contribution of TRPC Channels in Neuronal Excitotoxicity Associated With Neurodegenerative Disease and Ischemic Stroke. Frontiers in Cell and Developmental Biology. 8: 618663. PMID 33490083 DOI: 10.3389/fcell.2020.618663 |
0.443 |
|
| 2020 |
Medert R, Pironet A, Bacmeister L, Segin S, Londoño JEC, Vennekens R, Freichel M. Genetic background influences expression and function of the cation channel TRPM4 in the mouse heart. Basic Research in Cardiology. 115: 70. PMID 33205255 DOI: 10.1007/s00395-020-00831-x |
0.313 |
|
| 2020 |
Becker A, Mannebach S, Mathar I, Weissgerber P, Freichel M, Loodin AP, Fecher-Trost C, Belkacemi A, Beck A, Philipp SE. Control of Insulin Release by Transient Receptor Potential Melastatin 3 (TRPM3) Ion Channels. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 54: 1115-1131. PMID 33166100 DOI: 10.33594/000000304 |
0.306 |
|
| 2020 |
Hermann J, Bender M, Schumacher D, Woo MS, Shaposhnykov A, Rosenkranz SC, Kuryshev V, Meier C, Guse AH, Friese MA, Freichel M, Tsvilovskyy V. Contribution of NAADP to Glutamate-Evoked Changes in Ca Homeostasis in Mouse Hippocampal Neurons. Frontiers in Cell and Developmental Biology. 8: 496. PMID 32676502 DOI: 10.3389/Fcell.2020.00496 |
0.388 |
|
| 2020 |
Chu WG, Wang FD, Sun ZC, Ma SB, Wang X, Han WJ, Wang F, Bai ZT, Wu SX, Freichel M, Xie RG, Luo C. TRPC1/4/5 channels contribute to morphine-induced analgesic tolerance and hyperalgesia by enhancing spinal synaptic potentiation and structural plasticity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32359120 DOI: 10.1096/fj.202000154RR |
0.395 |
|
| 2020 |
Tsvilovskyy V, Solis-Lopez A, Almering J, Richter C, Birnbaumer L, Dietrich A, Freichel M. Analysis of Mrgprb2 Receptor-Evoked Ca Signaling in Bone Marrow Derived (BMMC) and Peritoneal (PMC) Mast Cells of TRPC-Deficient Mice. Frontiers in Immunology. 11: 564. PMID 32322252 DOI: 10.3389/Fimmu.2020.00564 |
0.306 |
|
| 2020 |
Camacho Londoño JE, Marx A, Kraft AE, Schürger A, Richter C, Dietrich A, Lipp P, Birnbaumer L, Freichel M. Angiotensin-II-Evoked Ca Entry in Murine Cardiac Fibroblasts Does Not Depend on TRPC Channels. Cells. 9. PMID 32013125 DOI: 10.3390/Cells9020322 |
0.309 |
|
| 2020 |
Masamune A, Kotani H, Sörgel FL, Chen JM, Hamada S, Sakaguchi R, Masson E, Nakano E, Kakuta Y, Niihori T, Funayama R, Shirota M, Hirano T, Kawamoto T, Hosokoshi A, ... ... Freichel M, et al. Variants That Affect Function of Calcium Channel TRPV6 Are Associated With Early-onset Chronic Pancreatitis: TRPV6 and pancreatitis. Gastroenterology. PMID 31930989 DOI: 10.1053/j.gastro.2020.01.005 |
0.346 |
|
| 2019 |
Schwarz Y, Oleinikov K, Schindeldecker B, Wyatt A, Weißgerber P, Flockerzi V, Boehm U, Freichel M, Bruns D. TRPC channels regulate Ca2+-signaling and short-term plasticity of fast glutamatergic synapses. Plos Biology. 17: e3000445. PMID 31536487 DOI: 10.1371/Journal.Pbio.3000445 |
0.537 |
|
| 2019 |
Blum T, Moreno-Pérez A, Pyrski M, Bufe B, Arifovic A, Weissgerber P, Freichel M, Zufall F, Leinders-Zufall T. Trpc5 deficiency causes hypoprolactinemia and altered function of oscillatory dopamine neurons in the arcuate nucleus. Proceedings of the National Academy of Sciences of the United States of America. PMID 31285329 DOI: 10.1073/Pnas.1905705116 |
0.334 |
|
| 2019 |
Egorov AV, Schumacher D, Medert R, Birnbaumer L, Freichel M, Draguhn A. TRPC channels are not required for graded persistent activity in entorhinal cortex neurons. Hippocampus. PMID 31002217 DOI: 10.1002/Hipo.23094 |
0.559 |
|
| 2019 |
Tiapko O, Shrestha N, Lindinger S, Guedes de la Cruz G, Graziani A, Klec C, Butorac C, Graier WF, Kubista H, Freichel M, Birnbaumer L, Romanin C, Glasnov T, Groschner K. Lipid-independent control of endothelial and neuronal TRPC3 channels by light. Chemical Science. 10: 2837-2842. PMID 30997005 DOI: 10.1039/c8sc05536j |
0.35 |
|
| 2018 |
Cheung SY, Henrot M, Al-Saad M, Baumann M, Muller H, Unger A, Rubaiy HN, Mathar I, Dinkel K, Nussbaumer P, Klebl B, Freichel M, Rode B, Trainor S, Clapcote SJ, et al. TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A. Oncotarget. 9: 29634-29643. PMID 30038709 DOI: 10.18632/Oncotarget.25659 |
0.326 |
|
| 2018 |
Tsvilovskyy V, Solís-López A, Schumacher D, Medert R, Roers A, Kriebs U, Freichel M. Deletion of Orai2 augments endogenous CRAC currents and degranulation in mast cells leading to enhanced anaphylaxis. Cell Calcium. 71: 24-33. PMID 29604961 DOI: 10.1016/j.ceca.2017.11.004 |
0.325 |
|
| 2018 |
Dutta Banik D, Martin LE, Freichel M, Torregrossa AM, Medler KF. TRPM4 and TRPM5 are both required for normal signaling in taste receptor cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 29311301 DOI: 10.1073/Pnas.1718802115 |
0.383 |
|
| 2017 |
Beck A, Götz V, Qiao S, Weissgerber P, Flockerzi V, Freichel M, Boehm U. Functional characterization of Transient Receptor Potential (TRP) Channel C5 in female murine gonadotropes. Endocrinology. PMID 28324107 DOI: 10.1210/En.2016-1810 |
0.428 |
|
| 2017 |
Danielczok J, Hertz L, Ruppenthal S, Kaiser E, Petkova-Kirova P, Bogdanova A, Krause E, Lipp P, Freichel M, Kaestner L, Birnbaumer L. Does Erythropoietin Regulate TRPC Channels in Red Blood Cells? Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 41: 1219-1228. PMID 28268218 DOI: 10.1159/000464384 |
0.393 |
|
| 2016 |
Rixecker T, Mathar I, Medert R, Mannebach S, Pfeifer A, Lipp P, Tsvilovskyy V, Freichel M. TRPM4-mediated control of FcεRI-evoked Ca(2+) elevation comprises enhanced plasmalemmal trafficking of TRPM4 channels in connective tissue type mast cells. Scientific Reports. 6: 32981. PMID 27624684 DOI: 10.1038/srep32981 |
0.309 |
|
| 2016 |
Kurland DB, Gerzanich V, Karimy JK, Woo SK, Vennekens R, Freichel M, Nilius B, Bryan J, Simard JM. The Sur1-Trpm4 channel regulates NOS2 transcription in TLR4-activated microglia. Journal of Neuroinflammation. 13: 130. PMID 27246103 DOI: 10.1186/s12974-016-0599-2 |
0.332 |
|
| 2015 |
Menigoz A, Ahmed T, Sabanov V, Philippaert K, Pinto S, Kerselaers S, Segal A, Freichel M, Voets T, Nilius B, Vennekens R, Balschun D. TRPM4-dependent post-synaptic depolarization is essential for the induction of NMDA receptor-dependent LTP in CA1 hippocampal neurons. Pflugers Archiv : European Journal of Physiology. PMID 26631168 DOI: 10.1007/s00424-015-1764-7 |
0.497 |
|
| 2015 |
Jha A, Singh AK, Weissgerber P, Freichel M, Flockerzi V, Flavell RA, Jha MK. Essential roles for Cavβ2 and Cav1 channels in thymocyte development and T cell homeostasis. Science Signaling. 8: ra103. PMID 26486172 DOI: 10.1126/Scisignal.Aac7538 |
0.335 |
|
| 2014 |
Uhl S, Mathar I, Vennekens R, Freichel M. Adenylyl cyclase-mediated effects contribute to increased Isoprenaline-induced cardiac contractility in TRPM4-deficient mice. Journal of Molecular and Cellular Cardiology. 74: 307-17. PMID 24972051 DOI: 10.1016/j.yjmcc.2014.06.007 |
0.352 |
|
| 2014 |
Freichel M, Tsvilovskyy V, Camacho-Londoño JE. TRPC4- and TRPC4-containing channels. Handbook of Experimental Pharmacology. 222: 85-128. PMID 24756704 DOI: 10.1007/978-3-642-54215-2_5 |
0.43 |
|
| 2014 |
Kang D, Wang J, Hogan JO, Vennekens R, Freichel M, White C, Kim D. Increase in cytosolic Ca2+ produced by hypoxia and other depolarizing stimuli activates a non-selective cation channel in chemoreceptor cells of rat carotid body. The Journal of Physiology. 592: 1975-92. PMID 24591572 DOI: 10.1113/Jphysiol.2013.266957 |
0.372 |
|
| 2014 |
Tian J, Thakur DP, Lu Y, Zhu Y, Freichel M, Flockerzi V, Zhu MX. Dual depolarization responses generated within the same lateral septal neurons by TRPC4-containing channels. Pflugers Archiv : European Journal of Physiology. 466: 1301-16. PMID 24121765 DOI: 10.1007/S00424-013-1362-5 |
0.467 |
|
| 2013 |
Boudes M, Uvin P, Pinto S, Freichel M, Birnbaumer L, Voets T, De Ridder D, Vennekens R. Crucial role of TRPC1 and TRPC4 in cystitis-induced neuronal sprouting and bladder overactivity. Plos One. 8: e69550. PMID 23922735 DOI: 10.1371/journal.pone.0069550 |
0.352 |
|
| 2013 |
Loga F, Domes K, Freichel M, Flockerzi V, Dietrich A, Birnbaumer L, Hofmann F, Wegener JW. The role of cGMP/cGKI signalling and Trpc channels in regulation of vascular tone. Cardiovascular Research. 100: 280-7. PMID 23832809 DOI: 10.1093/Cvr/Cvt176 |
0.393 |
|
| 2013 |
Phelan KD, Shwe UT, Abramowitz J, Wu H, Rhee SW, Howell MD, Gottschall PE, Freichel M, Flockerzi V, Birnbaumer L, Zheng F. Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms. Molecular Pharmacology. 83: 429-38. PMID 23188715 DOI: 10.1124/Mol.112.082271 |
0.386 |
|
| 2012 |
Quick K, Zhao J, Eijkelkamp N, Linley JE, Rugiero F, Cox JJ, Raouf R, Gringhuis M, Sexton JE, Abramowitz J, Taylor R, Forge A, Ashmore J, Kirkwood N, Kros CJ, ... ... Freichel M, et al. TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells. Open Biology. 2: 120068. PMID 22724068 DOI: 10.1098/rsob.120068 |
0.373 |
|
| 2012 |
Freichel M, Almering J, Tsvilovskyy V. The Role of TRP Proteins in Mast Cells. Frontiers in Immunology. 3: 150. PMID 22701456 DOI: 10.3389/fimmu.2012.00150 |
0.347 |
|
| 2012 |
Stroh O, Freichel M, Kretz O, Birnbaumer L, Hartmann J, Egger V. NMDA receptor-dependent synaptic activation of TRPC channels in olfactory bulb granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5737-46. PMID 22539836 DOI: 10.1523/JNEUROSCI.3753-11.2012 |
0.433 |
|
| 2012 |
Weissgerber P, Kriebs U, Tsvilovskyy V, Olausson J, Kretz O, Stoerger C, Mannebach S, Wissenbach U, Vennekens R, Middendorff R, Flockerzi V, Freichel M. Excision of Trpv6 gene leads to severe defects in epididymal Ca2+ absorption and male fertility much like single D541A pore mutation. The Journal of Biological Chemistry. 287: 17930-41. PMID 22427671 DOI: 10.1074/jbc.M111.328286 |
0.307 |
|
| 2012 |
Phelan KD, Mock MM, Kretz O, Shwe UT, Kozhemyakin M, Greenfield LJ, Dietrich A, Birnbaumer L, Freichel M, Flockerzi V, Zheng F. Heteromeric canonical transient receptor potential 1 and 4 channels play a critical role in epileptiform burst firing and seizure-induced neurodegeneration. Molecular Pharmacology. 81: 384-92. PMID 22144671 DOI: 10.1124/Mol.111.075341 |
0.531 |
|
| 2010 |
Mathar I, Vennekens R, Meissner M, Kees F, Van der Mieren G, Camacho Londoño JE, Uhl S, Voets T, Hummel B, van den Bergh A, Herijgers P, Nilius B, Flockerzi V, Schweda F, Freichel M. Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice. The Journal of Clinical Investigation. 120: 3267-79. PMID 20679729 DOI: 10.1172/JCI41348 |
0.376 |
|
| 2010 |
van der Eerden B, Schreuders-Koedam M, Boers-Sijmons B, Weissgerber P, Hoenderop J, Chiba H, Bindels R, Freichel M, van Leeuwen J. The transient receptor potential channel TRPV6 is dynamically expressed in osteoblasts and linked to mineralisation Bone. 47: S119-S120. DOI: 10.1016/J.BONE.2010.04.260 |
0.362 |
|
| 2009 |
Tsvilovskyy VV, Zholos AV, Aberle T, Philipp SE, Dietrich A, Zhu MX, Birnbaumer L, Freichel M, Flockerzi V. Deletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo. Gastroenterology. 137: 1415-24. PMID 19549525 DOI: 10.1053/J.Gastro.2009.06.046 |
0.371 |
|
| 2008 |
Hartmann J, Dragicevic E, Adelsberger H, Henning HA, Sumser M, Abramowitz J, Blum R, Dietrich A, Freichel M, Flockerzi V, Birnbaumer L, Konnerth A. TRPC3 channels are required for synaptic transmission and motor coordination. Neuron. 59: 392-8. PMID 18701065 DOI: 10.1016/J.Neuron.2008.06.009 |
0.54 |
|
| 2008 |
Otsuguro K, Tang J, Tang Y, Xiao R, Freichel M, Tsvilovskyy V, Ito S, Flockerzi V, Zhu MX, Zholos AV. Isoform-specific inhibition of TRPC4 channel by phosphatidylinositol 4,5-bisphosphate. The Journal of Biological Chemistry. 283: 10026-36. PMID 18230622 DOI: 10.1074/Jbc.M707306200 |
0.38 |
|
| 2007 |
Gross SA, Wissenbach U, Philipp SE, Freichel M, Cavalié A, Flockerzi V. Murine ORAI2 splice variants form functional Ca2+ release-activated Ca2+ (CRAC) channels Journal of Biological Chemistry. 282: 19375-19384. PMID 17463004 DOI: 10.1074/jbc.M701962200 |
0.378 |
|
| 2007 |
Vennekens R, Olausson J, Meissner M, Bloch W, Mathar I, Philipp SE, Schmitz F, Weissgerber P, Nilius B, Flockerzi V, Freichel M. Increased IgE-dependent mast cell activation and anaphylactic responses in mice lacking the calcium-activated nonselective cation channel TRPM4. Nature Immunology. 8: 312-20. PMID 17293867 DOI: 10.1038/ni1441 |
0.318 |
|
| 2004 |
Freichel M, Philipp S, Cavalié A, Flockerzi V. TRPC4 and TRPC4-deficient mice. Novartis Foundation Symposium. 258: 189-99; discussion 1. PMID 15104183 |
0.434 |
|
| 2003 |
Munsch T, Freichel M, Flockerzi V, Pape HC. Contribution of transient receptor potential channels to the control of GABA release from dendrites. Proceedings of the National Academy of Sciences of the United States of America. 100: 16065-70. PMID 14668438 DOI: 10.1073/pnas.2535311100 |
0.441 |
|
| 2003 |
Nilius B, Prenen J, Droogmans G, Voets T, Vennekens R, Freichel M, Wissenbach U, Flockerzi V. Voltage dependence of the Ca2+-activated cation channel TRPM4. The Journal of Biological Chemistry. 278: 30813-20. PMID 12799367 DOI: 10.1074/jbc.M305127200 |
0.343 |
|
| 2002 |
Murakami M, Fleischmann B, De Felipe C, Freichel M, Trost C, Ludwig A, Wissenbach U, Schwegler H, Hofmann F, Hescheler J, Flockerzi V, Cavalié A. Pain perception in mice lacking the beta3 subunit of voltage-activated calcium channels. The Journal of Biological Chemistry. 277: 40342-51. PMID 12161429 DOI: 10.1074/jbc.M203425200 |
0.312 |
|
| 2001 |
Freichel M, Suh SH, Pfeifer A, Schweig U, Trost C, Weissgerber P, Biel M, Philipp S, Freise D, Droogmans G, Hofmann F, Flockerzi V, Nilius B. Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice. Nature Cell Biology. 3: 121-7. PMID 11175743 DOI: 10.1038/35055019 |
0.345 |
|
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