Michael Xi Zhu - Publications

University of Texas Health Science Center at Houston, Houston, TX, United States 

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Shen X, Wang Q, Lin Y, Sreekrishna K, Jian Z, Zhu MX, Tian J. Voltage-dependent modulation of TRPA1 currents by diphenhydramine. Cell Calcium. 90: 102245. PMID 32634675 DOI: 10.1016/j.ceca.2020.102245  0.32
2020 Thakur DP, Wang Q, Jeon J, Tian JB, Zhu MX. Intracellular acidification facilitates receptor-operated TRPC4 activation through PLCδ1 in a Ca dependent manner. The Journal of Physiology. PMID 32338378 DOI: 10.1113/JP279658  0.44
2018 Ogunbayo OA, Duan J, Xiong J, Wang Q, Feng X, Ma J, Zhu MX, Evans AM. mTORC1 controls lysosomal Ca release through the two-pore channel TPC2. Science Signaling. 11. PMID 29636391 DOI: 10.1126/scisignal.aao5775  0.32
2017 Li Y, Hu H, Tian JB, Zhu MX, O'Neil RG. Dynamic coupling between TRPV4 and Ca-activated SK1/3 and IK1 K channels plays a critical role in regulating the K secretory BK channel in collecting duct cells. American Journal of Physiology. Renal Physiology. ajprenal.00037.2017. PMID 28274924 DOI: 10.1152/ajprenal.00037.2017  0.44
2016 Xiong J, Zhu MX. Regulation of lysosomal ion homeostasis by channels and transporters. Science China. Life Sciences. PMID 27430889 DOI: 10.1007/s11427-016-5090-x  0.52
2016 Li Y, Hu H, Butterworth MB, Tian JB, Zhu MX, O'Neil RG. Expression of a Diverse Array of Ca2+-Activated K+ Channels (SK1/3, IK1, BK) that Functionally Couple to the Mechanosensitive TRPV4 Channel in the Collecting Duct System of Kidney. Plos One. 11: e0155006. PMID 27159616 DOI: 10.1371/journal.pone.0155006  0.44
2016 Liu MG, Li HS, Li WG, Wu YJ, Deng SN, Huang C, Maximyuk O, Sukach V, Krishtal O, Zhu MX, Xu TL. Acid-sensing ion channel 1a contributes to hippocampal LTP inducibility through multiple mechanisms. Scientific Reports. 6: 23350. PMID 26996240 DOI: 10.1038/srep23350  0.52
2016 Jeon JP, Thakur DP, Tian JB, So I, Zhu MX. Regulator of G protein signaling and GoLoco proteins suppress TRPC4 channel function via acting at Gαi/o. The Biochemical Journal. PMID 26987813 DOI: 10.1042/BCJ20160214  0.44
2016 Gao L, Yang P, Qin P, Lu Y, Li X, Tian Q, Li Y, Xie C, Tian JB, Zhang C, Tian C, Zhu MX, Yao J. Selective potentiation of 2-APB-induced activation of TRPV1-3 channels by acid. Scientific Reports. 6: 20791. PMID 26876731 DOI: 10.1038/srep20791  0.44
2016 Thakur DP, Tian JB, Jeon J, Xiong J, Huang Y, Flockerzi V, Zhu MX. Critical roles of Gi/o proteins and phospholipase C-δ1 in the activation of receptor-operated TRPC4 channels. Proceedings of the National Academy of Sciences of the United States of America. PMID 26755577 DOI: 10.1073/pnas.1522294113  0.52
2015 Wang YZ, Wang JJ, Huang Y, Liu F, Zeng WZ, Li Y, Xiong ZG, Zhu MX, Xu TL. Tissue acidosis induces neuronal necroptosis via ASIC1a channel independent of its ionic conduction. Elife. 4. PMID 26523449 DOI: 10.7554/eLife.05682  0.52
2015 Wong CO, Palmieri M, Li J, Akhmedov D, Chao Y, Broadhead GT, Zhu MX, Berdeaux R, Collins CA, Sardiello M, Venkatachalam K. Diminished MTORC1-Dependent JNK Activation Underlies the Neurodevelopmental Defects Associated with Lysosomal Dysfunction. Cell Reports. PMID 26387958 DOI: 10.1016/j.celrep.2015.08.047  0.52
2015 Yang LP, Jiang FJ, Wu GS, Deng K, Wen M, Zhou X, Hong X, Zhu MX, Luo HR. Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice. Plos One. 10: e0136255. PMID 26317356 DOI: 10.1371/journal.pone.0136255  0.52
2015 Zhou Y, Wong CO, Cho KJ, van der Hoeven D, Liang H, Thakur DP, Luo J, Babic M, Zinsmaier KE, Zhu MX, Hu H, Venkatachalam K, Hancock JF. SIGNAL TRANSDUCTION. Membrane potential modulates plasma membrane phospholipid dynamics and K-Ras signaling. Science (New York, N.Y.). 349: 873-6. PMID 26293964 DOI: 10.1126/science.aaa5619  0.44
2015 Zhu Y, Lu Y, Qu C, Miller M, Tian J, Thakur DP, Zhu J, Deng Z, Hu X, Wu M, McManus OB, Li M, Hong X, Zhu MX, Luo HR. Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels. British Journal of Pharmacology. 172: 3495-509. PMID 25816897 DOI: 10.1111/bph.13140  0.52
2015 Zheng P, Noroski LM, Hanson IC, Chen Y, Lee ME, Huang Y, Zhu MX, Banerjee PP, Makedonas G, Orange JS, Shearer WT, Liu D. Molecular mechanisms of functional natural killer deficiency in patients with partial DiGeorge syndrome. The Journal of Allergy and Clinical Immunology. 135: 1293-302. PMID 25748067 DOI: 10.1016/j.jaci.2015.01.011  0.52
2015 Justice NJ, Huang L, Tian JB, Cole A, Pruski M, Hunt AJ, Flores R, Zhu MX, Arenkiel BR, Zheng H. Posttraumatic stress disorder-like induction elevates β-amyloid levels, which directly activates corticotropin-releasing factor neurons to exacerbate stress responses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 2612-23. PMID 25673853 DOI: 10.1523/JNEUROSCI.3333-14.2015  0.52
2015 Lin PH, Duann P, Komazaki S, Park KH, Li H, Sun M, Sermersheim M, Gumpper K, Parrington J, Galione A, Evans AM, Zhu MX, Ma J. Lysosomal two-pore channel subtype 2 (TPC2) regulates skeletal muscle autophagic signaling. The Journal of Biological Chemistry. 290: 3377-89. PMID 25480788 DOI: 10.1074/jbc.M114.608471  0.52
2015 Venkatachalam K, Wong CO, Zhu MX. The role of TRPMLs in endolysosomal trafficking and function. Cell Calcium. 58: 48-56. PMID 25465891 DOI: 10.1016/j.ceca.2014.10.008  0.52
2015 Ogunbayo OA, Zhu Y, Shen B, Agbani E, Li J, Ma J, Zhu MX, Evans AM. Organelle-specific subunit interactions of the vertebrate two-pore channel family. The Journal of Biological Chemistry. 290: 1086-95. PMID 25451935 DOI: 10.1074/jbc.M114.610493  0.52
2014 Tian J, Tep C, Benedick A, Saidi N, Ryu JC, Kim ML, Sadasivan S, Oberdick J, Smeyne R, Zhu MX, Yoon SO. p75 regulates Purkinje cell firing by modulating SK channel activity through Rac1. The Journal of Biological Chemistry. 289: 31458-72. PMID 25253694 DOI: 10.1074/jbc.M114.589937  0.52
2014 Sun H, Lu L, Zuo Y, Wang Y, Jiao Y, Zeng WZ, Huang C, Zhu MX, Zamponi GW, Zhou T, Xu TL, Cheng J, Li Y. Kainate receptor activation induces glycine receptor endocytosis through PKC deSUMOylation. Nature Communications. 5: 4980. PMID 25236484 DOI: 10.1038/ncomms5980  0.52
2014 Huang P, Zou Y, Zhong XZ, Cao Q, Zhao K, Zhu MX, Murrell-Lagnado R, Dong XP. P2X4 forms functional ATP-activated cation channels on lysosomal membranes regulated by luminal pH. The Journal of Biological Chemistry. 289: 17658-67. PMID 24817123 DOI: 10.1074/jbc.M114.552158  0.52
2014 Feng X, Huang Y, Lu Y, Xiong J, Wong CO, Yang P, Xia J, Chen D, Du G, Venkatachalam K, Xia X, Zhu MX. Drosophila TRPML forms PI(3,5)P2-activated cation channels in both endolysosomes and plasma membrane. The Journal of Biological Chemistry. 289: 4262-72. PMID 24375408 DOI: 10.1074/jbc.M113.506501  0.52
2014 Tian J, Thakur DP, Lu Y, Zhu Y, Freichel M, Flockerzi V, Zhu MX. Dual depolarization responses generated within the same lateral septal neurons by TRPC4-containing channels. Pflugers Archiv : European Journal of Physiology. 466: 1301-16. PMID 24121765 DOI: 10.1007/s00424-013-1362-5  0.52
2014 Wan X, Lu Y, Chen X, Xiong J, Zhou Y, Li P, Xia B, Li M, Zhu MX, Gao Z. Bimodal voltage dependence of TRPA1: Mutations of a key pore helix residue reveal strong intrinsic voltage-dependent inactivation Pflugers Archiv European Journal of Physiology. 466: 1273-1287. PMID 24092046 DOI: 10.1007/s00424-013-1345-6  0.52
2013 Feng S, Li H, Tai Y, Huang J, Su Y, Abramowitz J, Zhu MX, Birnbaumer L, Wang Y. Canonical transient receptor potential 3 channels regulate mitochondrial calcium uptake. Proceedings of the National Academy of Sciences of the United States of America. 110: 11011-6. PMID 23776229 DOI: 10.1073/pnas.1309531110  0.52
2013 Zhu J, Wu CF, Li X, Wu GS, Xie S, Hu QN, Deng Z, Zhu MX, Luo HR, Hong X. Synthesis, biological evaluation and molecular modeling of substituted 2-aminobenzimidazoles as novel inhibitors of acetylcholinesterase and butyrylcholinesterase. Bioorganic & Medicinal Chemistry. 21: 4218-24. PMID 23719283 DOI: 10.1016/j.bmc.2013.05.001  0.52
2013 Beck A, Speicher T, Stoerger C, Sell T, Dettmer V, Jusoh SA, Abdulmughni A, Cavalié A, Philipp SE, Zhu MX, Helms V, Wissenbach U, Flockerzi V. Conserved gating elements in TRPC4 and TRPC5 channels. The Journal of Biological Chemistry. 288: 19471-83. PMID 23677990 DOI: 10.1074/jbc.M113.478305  0.52
2012 Wang X, Zhang X, Dong XP, Samie M, Li X, Cheng X, Goschka A, Shen D, Zhou Y, Harlow J, Zhu MX, Clapham DE, Ren D, Xu H. TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes. Cell. 151: 372-83. PMID 23063126 DOI: 10.1016/j.cell.2012.08.036  0.52
2012 Alexander JK, Cox GM, Tian JB, Zha AM, Wei P, Kigerl KA, Reddy MK, Dagia NM, Sielecki T, Zhu MX, Satoskar AR, McTigue DM, Whitacre CC, Popovich PG. Macrophage migration inhibitory factor (MIF) is essential for inflammatory and neuropathic pain and enhances pain in response to stress. Experimental Neurology. 236: 351-62. PMID 22575600 DOI: 10.1016/j.expneurol.2012.04.018  0.52
2012 Cheng W, Yang F, Liu S, Colton CK, Wang C, Cui Y, Cao X, Zhu MX, Sun C, Wang K, Zheng J. Heteromeric heat-sensitive transient receptor potential channels exhibit distinct temperature and chemical response. The Journal of Biological Chemistry. 287: 7279-88. PMID 22184123 DOI: 10.1074/jbc.M111.305045  0.52
2011 Sarria I, Ling J, Zhu MX, Gu JG. TRPM8 acute desensitization is mediated by calmodulin and requires PIP(2): distinction from tachyphylaxis. Journal of Neurophysiology. 106: 3056-66. PMID 21900509 DOI: 10.1152/jn.00544.2011  0.52
2011 Miller M, Shi J, Zhu Y, Kustov M, Tian JB, Stevens A, Wu M, Xu J, Long S, Yang P, Zholos AV, Salovich JM, Weaver CD, Hopkins CR, Lindsley CW, ... ... Zhu MX, et al. Identification of ML204, a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels. The Journal of Biological Chemistry. 286: 33436-46. PMID 21795696 DOI: 10.1074/jbc.M111.274167  0.52
2011 Hester ME, Murtha MJ, Song S, Rao M, Miranda CJ, Meyer K, Tian J, Boulting G, Schaffer DV, Zhu MX, Pfaff SL, Gage FH, Kaspar BK. Rapid and efficient generation of functional motor neurons from human pluripotent stem cells using gene delivered transcription factor codes. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1905-12. PMID 21772256 DOI: 10.1038/mt.2011.135  0.52
2011 Ogunbayo OA, Zhu Y, Rossi D, Sorrentino V, Ma J, Zhu MX, Evans AM. Cyclic adenosine diphosphate ribose activates ryanodine receptors, whereas NAADP activates two-pore domain channels. The Journal of Biological Chemistry. 286: 9136-40. PMID 21216967 DOI: 10.1074/jbc.M110.202002  0.52
2010 Arredouani A, Evans AM, Ma J, Parrington J, Zhu MX, Galione A. An emerging role for NAADP-mediated Ca2+ signaling in the pancreatic β-cell. Islets. 2: 323-30. PMID 21099331 DOI: 10.4161/isl.2.5.12747  0.52
2010 Treves S, Vukcevic M, Griesser J, Armstrong CF, Zhu MX, Zorzato F. Agonist-activated Ca2+ influx occurs at stable plasma membrane and endoplasmic reticulum junctions. Journal of Cell Science. 123: 4170-81. PMID 21062895 DOI: 10.1242/jcs.068387  0.52
2010 Pitt SJ, Funnell TM, Sitsapesan M, Venturi E, Rietdorf K, Ruas M, Ganesan A, Gosain R, Churchill GC, Zhu MX, Parrington J, Galione A, Sitsapesan R. TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+. The Journal of Biological Chemistry. 285: 35039-46. PMID 20720007 DOI: 10.1074/jbc.M110.156927  0.52
2010 Henderson BJ, Pavlovicz RE, Allen JD, González-Cestari TF, Orac CM, Bonnell AB, Zhu MX, Boyd RT, Li C, Bergmeier SC, McKay DB. Negative allosteric modulators that target human alpha4beta2 neuronal nicotinic receptors. The Journal of Pharmacology and Experimental Therapeutics. 334: 761-74. PMID 20551292 DOI: 10.1124/jpet.110.168211  0.52
2010 Colton CK, Kong Q, Lai L, Zhu MX, Seyb KI, Cuny GD, Xian J, Glicksman MA, Lin CL. Identification of translational activators of glial glutamate transporter EAAT2 through cell-based high-throughput screening: an approach to prevent excitotoxicity. Journal of Biomolecular Screening. 15: 653-62. PMID 20508255 DOI: 10.1177/1087057110370998  0.52
2010 Ruas M, Rietdorf K, Arredouani A, Davis LC, Lloyd-Evans E, Koegel H, Funnell TM, Morgan AJ, Ward JA, Watanabe K, Cheng X, Churchill GC, Zhu MX, Platt FM, Wessel GM, et al. Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking. Current Biology : Cb. 20: 703-9. PMID 20346675 DOI: 10.1016/j.cub.2010.02.049  0.52
2010 Zhu MX, Ma J, Parrington J, Calcraft PJ, Galione A, Evans AM. Calcium signaling via two-pore channels: local or global, that is the question. American Journal of Physiology. Cell Physiology. 298: C430-41. PMID 20018950 DOI: 10.1152/ajpcell.00475.2009  0.52
2010 Hu H, Tian J, Zhu Y, Wang C, Xiao R, Herz JM, Wood JD, Zhu MX. Activation of TRPA1 channels by fenamate nonsteroidal anti-inflammatory drugs. PflüGers Archiv : European Journal of Physiology. 459: 579-92. PMID 19888597 DOI: 10.1007/s00424-009-0749-9  0.52
2009 Tsvilovskyy VV, Zholos AV, Aberle T, Philipp SE, Dietrich A, Zhu MX, Birnbaumer L, Freichel M, Flockerzi V. Deletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo. Gastroenterology. 137: 1415-24. PMID 19549525 DOI: 10.1053/j.gastro.2009.06.046  0.52
2009 Galione A, Evans AM, Ma J, Parrington J, Arredouani A, Cheng X, Zhu MX. The acid test: the discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca(2+) release channels. PflüGers Archiv : European Journal of Physiology. 458: 869-76. PMID 19475418 DOI: 10.1007/s00424-009-0682-y  0.52
2009 Calcraft PJ, Ruas M, Pan Z, Cheng X, Arredouani A, Hao X, Tang J, Rietdorf K, Teboul L, Chuang KT, Lin P, Xiao R, Wang C, Zhu Y, Lin Y, ... ... Zhu MX, et al. NAADP mobilizes calcium from acidic organelles through two-pore channels. Nature. 459: 596-600. PMID 19387438 DOI: 10.1038/nature08030  0.52
2009 Hu H, Bandell M, Petrus MJ, Zhu MX, Patapoutian A. Zinc activates damage-sensing TRPA1 ion channels. Nature Chemical Biology. 5: 183-90. PMID 19202543 DOI: 10.1038/nchembio.146  0.52
2009 Sidiropoulou K, Lu FM, Fowler MA, Xiao R, Phillips C, Ozkan ED, Zhu MX, White FJ, Cooper DC. Dopamine modulates an mGluR5-mediated depolarization underlying prefrontal persistent activity. Nature Neuroscience. 12: 190-9. PMID 19169252 DOI: 10.1038/nn.2245  0.52
2009 González-Cestari TF, Henderson BJ, Pavlovicz RE, McKay SB, El-Hajj RA, Pulipaka AB, Orac CM, Reed DD, Boyd RT, Zhu MX, Li C, Bergmeier SC, McKay DB. Effect of novel negative allosteric modulators of neuronal nicotinic receptors on cells expressing native and recombinant nicotinic receptors: implications for drug discovery. The Journal of Pharmacology and Experimental Therapeutics. 328: 504-15. PMID 18984653 DOI: 10.1124/jpet.108.144576  0.52
2009 Iscru E, Serinagaoglu Y, Schilling K, Tian J, Bowers-Kidder SL, Zhang R, Morgan JI, DeVries AC, Nelson RJ, Zhu MX, Oberdick J. Sensorimotor enhancement in mouse mutants lacking the Purkinje cell-specific Gi/o modulator, Pcp2(L7). Molecular and Cellular Neurosciences. 40: 62-75. PMID 18930827 DOI: 10.1016/j.mcn.2008.09.002  0.52
2008 Otsuguro K, Tang J, Tang Y, Xiao R, Freichel M, Tsvilovskyy V, Ito S, Flockerzi V, Zhu MX, Zholos AV. Isoform-specific inhibition of TRPC4 channel by phosphatidylinositol 4,5-bisphosphate. The Journal of Biological Chemistry. 283: 10026-36. PMID 18230622 DOI: 10.1074/jbc.M707306200  0.52
2008 Xiao R, Tang J, Wang C, Colton CK, Tian J, Zhu MX. Calcium plays a central role in the sensitization of TRPV3 channel to repetitive stimulations. The Journal of Biological Chemistry. 283: 6162-74. PMID 18178557 DOI: 10.1074/jbc.M706535200  0.52
2007 Mutafova-Yambolieva VN, Hwang SJ, Hao X, Chen H, Zhu MX, Wood JD, Ward SM, Sanders KM. Beta-nicotinamide adenine dinucleotide is an inhibitory neurotransmitter in visceral smooth muscle. Proceedings of the National Academy of Sciences of the United States of America. 104: 16359-64. PMID 17913880 DOI: 10.1073/pnas.0705510104  0.52
2007 McKay DB, Chang C, González-Cestari TF, McKay SB, El-Hajj RA, Bryant DL, Zhu MX, Swaan PW, Arason KM, Pulipaka AB, Orac CM, Bergmeier SC. Analogs of methyllycaconitine as novel noncompetitive inhibitors of nicotinic receptors: pharmacological characterization, computational modeling, and pharmacophore development. Molecular Pharmacology. 71: 1288-97. PMID 17308033 DOI: 10.1124/mol.106.033233  0.52
2006 Hu HZ, Xiao R, Wang C, Gao N, Colton CK, Wood JD, Zhu MX. Potentiation of TRPV3 channel function by unsaturated fatty acids. Journal of Cellular Physiology. 208: 201-12. PMID 16557504 DOI: 10.1002/jcp.20648  0.52
2005 Kinoshita-Kawada M, Tang J, Xiao R, Kaneko S, Foskett JK, Zhu MX. Inhibition of TRPC5 channels by Ca2+-binding protein 1 in Xenopus oocytes. PflüGers Archiv : European Journal of Physiology. 450: 345-54. PMID 15895247 DOI: 10.1007/s00424-005-1419-1  0.52
2004 Treves S, Franzini-Armstrong C, Moccagatta L, Arnoult C, Grasso C, Schrum A, Ducreux S, Zhu MX, Mikoshiba K, Girard T, Smida-Rezgui S, Ronjat M, Zorzato F. Junctate is a key element in calcium entry induced by activation of InsP3 receptors and/or calcium store depletion. The Journal of Cell Biology. 166: 537-48. PMID 15302852 DOI: 10.1083/jcb.200404079  0.52
2004 Wang C, Hu HZ, Colton CK, Wood JD, Zhu MX. An alternative splicing product of the murine trpv1 gene dominant negatively modulates the activity of TRPV1 channels. The Journal of Biological Chemistry. 279: 37423-30. PMID 15234965 DOI: 10.1074/jbc.M407205200  0.52
2004 Hu HZ, Gu Q, Wang C, Colton CK, Tang J, Kinoshita-Kawada M, Lee LY, Wood JD, Zhu MX. 2-aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3. The Journal of Biological Chemistry. 279: 35741-8. PMID 15194687 DOI: 10.1074/jbc.M404164200  0.52
2002 Montell C, Birnbaumer L, Flockerzi V, Bindels RJ, Bruford EA, Caterina MJ, Clapham DE, Harteneck C, Heller S, Julius D, Kojima I, Mori Y, Penner R, Prawitt D, Scharenberg AM, ... ... Zhu MX, et al. A unified nomenclature for the superfamily of TRP cation channels. Molecular Cell. 9: 229-31. PMID 11864597 DOI: 10.1016/S1097-2765(02)00448-3  0.52
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