| Year |
Citation |
Score |
| 2023 |
Alexander SPH, Mathie AA, Peters JA, Veale EL, Striessnig J, Kelly E, Armstrong JF, Faccenda E, Harding SD, Davies JA, Aldrich RW, Attali B, Baggetta AM, Becirovic E, Biel M, ... ... Zhu M, et al. The Concise Guide to PHARMACOLOGY 2023/24: Ion channels. British Journal of Pharmacology. S145-S222. PMID 38123150 DOI: 10.1111/bph.16178 |
0.569 |
|
| 2023 |
Tian J, Bavencoffe AG, Zhu MX, Walters ET. Readiness of nociceptor cell bodies to generate spontaneous activity results from background activity of diverse ion channels and high input resistance. Pain. PMID 37862056 DOI: 10.1097/j.pain.0000000000003091 |
0.368 |
|
| 2023 |
Yadav GP, Wang H, Ouwendijk J, Cross S, Wang Q, Qin F, Verkade P, Zhu MX, Jiang QX. Chromogranin B (CHGB) is dimorphic and responsible for dominant anion channels delivered to cell surface via regulated secretion. Frontiers in Molecular Neuroscience. 16: 1205516. PMID 37435575 DOI: 10.3389/fnmol.2023.1205516 |
0.306 |
|
| 2023 |
Zhu MX. High resolution cryo-EM structures of TRPC5-Gα complexes reveal direct activation of an ion channel by Gα-GTP. Cell Calcium. 113: 102767. PMID 37321139 DOI: 10.1016/j.ceca.2023.102767 |
0.424 |
|
| 2023 |
Xue C, Zhang X, Ge H, Tang Q, Jeon J, Zhao F, Wang Y, Zhu MX, Cao Z. Total flavone of flowers of Abelmoschus manihot (L.) Medic inhibits the expression of adhesion molecules in primary mesenteric arterial endothelial cells and ameliorates dextran sodium sulphate-induced ulcerative colitis in mice. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 112: 154713. PMID 36857970 DOI: 10.1016/j.phymed.2023.154713 |
0.494 |
|
| 2023 |
Wang Q, Wang Z, Wang Y, Qi Z, Bai D, Wang C, Chen Y, Xu W, Zhu X, Jeon J, Xiong J, Hao C, Zhu MX, Wei A, Li W. A gain-of-function TPC2 variant R210C increases affinity to PI(3,5)P and causes lysosome acidification and hypopigmentation. Nature Communications. 14: 226. PMID 36641477 DOI: 10.1038/s41467-023-35786-9 |
0.616 |
|
| 2022 |
Ma S, Zhu MX. Transient Receptor Potential Channels in Cardiovascular and Renal Diseases. Cells. 11. PMID 36552723 DOI: 10.3390/cells11243960 |
0.354 |
|
| 2022 |
Sun MY, Zhang X, Yu PC, Liu D, Yang Y, Cui WW, Yang XN, Lei YT, Li XH, Wang WH, Cao P, Wang HS, Zhu MX, Li CZ, Wang R, et al. Vanilloid agonist-mediated activation of TRPV1 channels requires coordinated movement of the S1-S4 bundle rather than a quiescent state. Science Bulletin. 67: 1062-1076. PMID 36546250 DOI: 10.1016/j.scib.2022.02.016 |
0.333 |
|
| 2022 |
Kodkandla G, West SJ, Wang Q, Tewari R, Zhu MX, Akimzhanov AM, Boehning D. Dynamic S-acylation of the ER-resident protein stromal interaction molecule 1 (STIM1) is required for store-operated Ca entry. The Journal of Biological Chemistry. 102303. PMID 35934052 DOI: 10.1016/j.jbc.2022.102303 |
0.312 |
|
| 2022 |
Wang Q, Zhu MX. NAADP-Dependent TPC Current. Handbook of Experimental Pharmacology. PMID 35902437 DOI: 10.1007/164_2022_606 |
0.419 |
|
| 2022 |
Feng X, Xiong J, Cai W, Tian JB, Zhu MX. The Three Two-Pore Channel Subtypes from Rabbit Exhibit Distinct Sensitivity to Phosphoinositides, Voltage, and Extracytosolic pH. Cells. 11. PMID 35805090 DOI: 10.3390/cells11132006 |
0.302 |
|
| 2022 |
Tian JB, Yang J, Joslin WC, Flockerzi V, Prescott SA, Birnbaumer L, Zhu MX. TRPC4 and GIRK channels underlie neuronal coding of firing patterns that reflect G-G coincidence signals of variable strengths. Proceedings of the National Academy of Sciences of the United States of America. 119: e2120870119. PMID 35544691 DOI: 10.1073/pnas.2120870119 |
0.456 |
|
| 2022 |
Azoulay IS, Qi X, Rozenfeld M, Liu F, Hu Q, Ben Kasus Nissim T, Stavsky A, Zhu MX, Xu TL, Sekler I. ASIC1a senses lactate uptake to regulate metabolism in neurons. Redox Biology. 51: 102253. PMID 35247821 DOI: 10.1016/j.redox.2022.102253 |
0.338 |
|
| 2022 |
West SJ, Kodakandla G, Wang Q, Tewari R, Zhu MX, Boehning D, Akimzhanov AM. S-acylation of Orai1 regulates store-operated Ca2+ entry. Journal of Cell Science. 135. PMID 34156466 DOI: 10.1242/jcs.258579 |
0.393 |
|
| 2021 |
Alexander SP, Mathie A, Peters JA, Veale EL, Striessnig J, Kelly E, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Aldrich RW, Attali B, Baggetta AM, ... ... Zhu M, et al. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels. British Journal of Pharmacology. 178: S157-S245. PMID 34529831 DOI: 10.1111/bph.15539 |
0.57 |
|
| 2021 |
Yang PL, Li XH, Wang J, Ma XF, Zhou BY, Jiao YF, Wang WH, Cao P, Zhu MX, Li PW, Xiao ZH, Li CZ, Guo CR, Lei YT, Yu Y. GSK1702934A and M085 directly activate TRPC6 via a mechanism of stimulating the extracellular cavity formed by the pore helix and transmembrane helix S6. The Journal of Biological Chemistry. 101125. PMID 34461094 DOI: 10.1016/j.jbc.2021.101125 |
0.315 |
|
| 2021 |
Zhan Q, Jeon J, Li Y, Huang Y, Xiong J, Wang Q, Xu TL, Li Y, Ji FH, Du G, Zhu MX. CAMK2/CaMKII activates MLKL in short-term starvation to facilitate autophagic flux. Autophagy. 1-19. PMID 34282994 DOI: 10.1080/15548627.2021.1954348 |
0.576 |
|
| 2021 |
Wang H, Yang P, Lu Y, Wang J, Jeon J, Wang Q, Tian JB, Zang B, Yu Y, Zhu MX. Mechanisms of proton inhibition and sensitization of the cation channel TRPV3. The Journal of General Physiology. 153. PMID 33320167 DOI: 10.1085/jgp.202012663 |
0.655 |
|
| 2020 |
Jeon J, Bu F, Sun G, Tian JB, Ting SM, Li J, Aronowski J, Birnbaumer L, Freichel M, Zhu MX. Contribution of TRPC Channels in Neuronal Excitotoxicity Associated With Neurodegenerative Disease and Ischemic Stroke. Frontiers in Cell and Developmental Biology. 8: 618663. PMID 33490083 DOI: 10.3389/fcell.2020.618663 |
0.719 |
|
| 2020 |
Jeon J, Tian JB, Zhu MX. TRPC4 as a coincident detector of G and G signaling: mechanisms and pathophysiological implications. Current Opinion in Physiology. 17: 34-41. PMID 32851198 DOI: 10.1016/J.Cophys.2020.06.008 |
0.678 |
|
| 2020 |
Shen X, Wang Q, Lin Y, Sreekrishna K, Jian Z, Zhu MX, Tian J. Voltage-dependent modulation of TRPA1 currents by diphenhydramine. Cell Calcium. 90: 102245. PMID 32634675 DOI: 10.1016/J.Ceca.2020.102245 |
0.398 |
|
| 2020 |
Wang Y, Li H, Xue C, Chen H, Xue Y, Zhao F, Zhu MX, Cao Z. TRPV3 enhances skin keratinocyte proliferation through EGFR-dependent signaling pathways. Cell Biology and Toxicology. PMID 32535744 DOI: 10.1007/s10565-020-09536-2 |
0.32 |
|
| 2020 |
Liu Z, Wang P, Lu S, Guo R, Gao W, Tong H, Yin Y, Han X, Liu T, Chen X, Zhu MX, Yang Z. Liquiritin, a novel inhibitor of TRPV1 and TRPA1, protects against LPS-induced acute lung injury. Cell Calcium. 88: 102198. PMID 32388008 DOI: 10.1016/J.Ceca.2020.102198 |
0.35 |
|
| 2020 |
Thakur DP, Wang Q, Jeon J, Tian JB, Zhu MX. Intracellular acidification facilitates receptor-operated TRPC4 activation through PLCδ1 in a Ca dependent manner. The Journal of Physiology. PMID 32338378 DOI: 10.1113/Jp279658 |
0.794 |
|
| 2020 |
Yang L, Han B, Zhang M, Wang YH, Tao K, Zhu MX, He K, Zhang ZG, Hou S. Activation of BK Channels Prevents Hepatic Stellate Cell Activation and Liver Fibrosis Through the Suppression of TGFβ1/SMAD3 and JAK/STAT3 Profibrotic Signaling Pathways. Frontiers in Pharmacology. 11: 165. PMID 32210801 DOI: 10.3389/Fphar.2020.00165 |
0.363 |
|
| 2020 |
Wang H, Cheng X, Tian J, Xiao Y, Tian T, Xu F, Hong X, Zhu MX. TRPC channels: Structure, function, regulation and recent advances in small molecular probes. Pharmacology & Therapeutics. 107497. PMID 32004513 DOI: 10.1016/J.Pharmthera.2020.107497 |
0.5 |
|
| 2020 |
Wang JJ, Liu F, Yang F, Wang YZ, Qi X, Li Y, Hu Q, Zhu MX, Xu TL. Disruption of auto-inhibition underlies conformational signaling of ASIC1a to induce neuronal necroptosis. Nature Communications. 11: 475. PMID 31980622 DOI: 10.1038/S41467-019-13873-0 |
0.372 |
|
| 2020 |
Savic Azoulay I, Liu F, Qin H, Rozenfeld M, Ben Kasus Nissim T, Zhu MX, Sekler I, Xu TL. ASIC1a Channels Regulate Mitochondrial Ion Signaling and Energy Homeostasis in Neurons. Journal of Neurochemistry. e14971. PMID 31976561 DOI: 10.1111/Jnc.14971 |
0.413 |
|
| 2019 |
Xiong J, He J, Xie WP, Hinojosa E, Ambati CSR, Putluri N, Kim HE, Zhu MX, Du G. Rapid affinity purification of intracellular organelles using twin strep tag. Journal of Cell Science. PMID 31780580 DOI: 10.1242/Jcs.235390 |
0.301 |
|
| 2019 |
Sun LF, Liu Y, Wang J, Huang LD, Yang Y, Cheng XY, Fan YZ, Zhu MX, Liang H, Tian Y, Wang HS, Guo CR, Yu Y. Altered allostery of the left flipper domain underlies the weak ATP-response of rat P2X5 receptors. The Journal of Biological Chemistry. PMID 31727741 DOI: 10.1074/Jbc.Ra119.009959 |
0.407 |
|
| 2019 |
Li HS, Su XY, Song XL, Qi X, Li Y, Wang RQ, Maximyuk O, Krishtal O, Wang T, Fang H, Liao L, Cao H, Zhang YQ, Zhu MX, Liu MG, et al. Protein kinase C lambda mediates acid-sensing ion channel 1a-dependent cortical synaptic plasticity and pain hypersensitivity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31101759 DOI: 10.1523/Jneurosci.0213-19.2019 |
0.305 |
|
| 2019 |
Tang B, Wu J, Zhu MX, Sun X, Liu J, Xie R, Dong TX, Xiao Y, Carethers JM, Yang S, Dong H. VPAC1 couples with TRPV4 channel to promote calcium-dependent gastric cancer progression via a novel autocrine mechanism. Oncogene. PMID 30692637 DOI: 10.1038/S41388-019-0709-6 |
0.327 |
|
| 2019 |
Jeon J, Zhu MX. TRPC4 Channels are a Key Player in Hippocampal Neuronal Development Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.2893 |
0.648 |
|
| 2018 |
Wang Q, Wang Q, Song XL, Jiang Q, Wu YJ, Li Y, Yuan TF, Zhang S, Xu NJ, Zhu MX, Li WG, Xu TL. Fear extinction requires ASIC1a-dependent regulation of hippocampal-prefrontal correlates. Science Advances. 4: eaau3075. PMID 30417090 DOI: 10.1126/Sciadv.Aau3075 |
0.33 |
|
| 2018 |
Yu Z, Wu YJ, Wang YZ, Liu DS, Song XL, Jiang Q, Li Y, Zhang S, Xu NJ, Zhu MX, Li WG, Xu TL. The acid-sensing ion channel ASIC1a mediates striatal synapse remodeling and procedural motor learning. Science Signaling. 11. PMID 30087178 DOI: 10.1126/Scisignal.Aar4481 |
0.356 |
|
| 2018 |
Ding M, Wang H, Qu C, Xu F, Zhu Y, Lv G, Lu Y, Zhou Q, Zhou H, Zeng X, Zhang J, Yan C, Lin J, Luo HR, Deng Z, ... ... Zhu MX, et al. Pyrazolo[1,5-a]pyrimidine TRPC6 Antagonists for the Treatment of Gastric Cancer. Cancer Letters. PMID 29859875 DOI: 10.1016/J.Canlet.2018.05.041 |
0.394 |
|
| 2018 |
Wang J, Wang Y, Cui WW, Huang Y, Yang Y, Liu Y, Zhao WS, Cheng XY, Sun WS, Cao P, Zhu MX, Wang R, Hattori M, Yu Y. Druggable negative allosteric site of P2X3 receptors. Proceedings of the National Academy of Sciences of the United States of America. PMID 29674445 DOI: 10.1073/Pnas.1800907115 |
0.407 |
|
| 2018 |
Wang Y, Gao Y, Tian Q, Deng Q, Wang Y, Zhou T, Liu Q, Mei K, Wang Y, Liu H, Ma R, Ding Y, Rong W, Cheng J, Yao J, ... ... Zhu MX, et al. TRPV1 SUMOylation regulates nociceptive signaling in models of inflammatory pain. Nature Communications. 9: 1529. PMID 29670121 DOI: 10.1038/S41467-018-03974-7 |
0.389 |
|
| 2018 |
Ogunbayo OA, Duan J, Xiong J, Wang Q, Feng X, Ma J, Zhu MX, Evans AM. mTORC1 controls lysosomal Ca release through the two-pore channel TPC2. Science Signaling. 11. PMID 29636391 DOI: 10.1126/Scisignal.Aao5775 |
0.47 |
|
| 2018 |
Jeon J, Guanghua S, Tian J, Ting S, Aronowski J, Zhu MX. Ischemic Neuronal Cell Death Mediated by TRPC Channels Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.3462 |
0.649 |
|
| 2018 |
Wang Q, Thakur DP, Tian J, Jeon J, Zhu MX. Mechanism of Regulation of Gi/o-Mediated TRPC4 Activation by Intracellular Protons Biophysical Journal. 114: 397a. DOI: 10.1016/J.Bpj.2017.11.2197 |
0.767 |
|
| 2017 |
Yang XN, Niu YY, Liu Y, Yang Y, Jin W, Cheng XY, Liang H, Wang HS, Hu YM, Lu XY, Zhu MX, Xu TL, Tian Y, Yu Y. The nonproton ligand of acid-sensing ion channel 3 activates mollusk-specific FaNaC channels via a mechanism independent of native FMRFamide peptide. The Journal of Biological Chemistry. PMID 29123030 DOI: 10.1074/Jbc.M117.814707 |
0.471 |
|
| 2017 |
Xie R, Xu J, Xiao YF, Wu J, Wan H, Tang B, Liu J, Fan Y, Wang SM, Wu YY, Dong TX, Zhu M, Carethers JM, Dong H, Yang SM. Calcium promotes human gastric cancer via a novel coupling of calcium-sensing receptor and TRPV4 channel. Cancer Research. PMID 28951460 DOI: 10.1158/0008-5472.Can-17-0360 |
0.419 |
|
| 2017 |
Bavencoffe A, Zhu MX, Tian JB. New Aspects of the Contribution of ER to SOCE Regulation: TRPC Proteins as a Link Between Plasma Membrane Ion Transport and Intracellular Ca(2+) Stores. Advances in Experimental Medicine and Biology. 993: 239-255. PMID 28900918 DOI: 10.1007/978-3-319-57732-6_13 |
0.563 |
|
| 2017 |
Jiang YM, Huang C, Peng Z, Han SL, Li WG, Zhu MX, Xu TL. Acidosis counteracts itch tachyphylaxis to consecutive pruritogen exposure dependent on acid-sensing ion channel 3. Molecular Pain. 13: 1744806917721114. PMID 28745101 DOI: 10.1177/1744806917721114 |
0.44 |
|
| 2017 |
Zhu MX. A well-known potassium channel plays a critical role in lysosomes. The Journal of Cell Biology. PMID 28512142 DOI: 10.1083/Jcb.201704017 |
0.447 |
|
| 2017 |
Qu C, Ding M, Zhu Y, Lu Y, Du J, Miller MR, Tian J, Zhu J, Xu J, Wen M, Er-Bu A, Wang J, Xiao Y, Wu M, McManus OB, ... ... Zhu MX, et al. Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels. Journal of Medicinal Chemistry. PMID 28395140 DOI: 10.1021/Acs.Jmedchem.7B00304 |
0.469 |
|
| 2017 |
Li Y, Hu H, Tian JB, Zhu MX, O'Neil RG. Dynamic coupling between TRPV4 and Ca-activated SK1/3 and IK1 K channels plays a critical role in regulating the K secretory BK channel in collecting duct cells. American Journal of Physiology. Renal Physiology. ajprenal.00037.2017. PMID 28274924 DOI: 10.1152/Ajprenal.00037.2017 |
0.505 |
|
| 2017 |
Jeon J, Sun G, Tian J, Ting S, Aronowski J, Zhu MX. The Role of TRPC Channels in Ischemic Neuronal Cell Death Biophysical Journal. 112: 4-8. DOI: 10.1016/J.Bpj.2016.11.2207 |
0.406 |
|
| 2017 |
Zhu MX, Tian J. Analog-To-Digital Conversion of Differential Metabotropic Inputs to Lateral Septal Neurons by the Combined Action of TRPC4 and GIRK Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.2205 |
0.502 |
|
| 2016 |
Shang S, Zhu F, Liu B, Chai Z, Wu Q, Hu M, Wang Y, Huang R, Zhang X, Wu X, Sun L, Wang Y, Wang L, Xu H, Teng S, ... ... Zhu MX, et al. Intracellular TRPA1 mediates Ca2+ release from lysosomes in dorsal root ganglion neurons. The Journal of Cell Biology. PMID 27799370 DOI: 10.1083/Jcb.201603081 |
0.462 |
|
| 2016 |
Xiong J, Zhu MX. Regulation of lysosomal ion homeostasis by channels and transporters. Science China. Life Sciences. PMID 27430889 DOI: 10.1007/S11427-016-5090-X |
0.427 |
|
| 2016 |
Li Y, Hu H, Butterworth MB, Tian JB, Zhu MX, O'Neil RG. Expression of a Diverse Array of Ca2+-Activated K+ Channels (SK1/3, IK1, BK) that Functionally Couple to the Mechanosensitive TRPV4 Channel in the Collecting Duct System of Kidney. Plos One. 11: e0155006. PMID 27159616 DOI: 10.1371/Journal.Pone.0155006 |
0.516 |
|
| 2016 |
Liu MG, Li HS, Li WG, Wu YJ, Deng SN, Huang C, Maximyuk O, Sukach V, Krishtal O, Zhu MX, Xu TL. Acid-sensing ion channel 1a contributes to hippocampal LTP inducibility through multiple mechanisms. Scientific Reports. 6: 23350. PMID 26996240 DOI: 10.1038/Srep23350 |
0.348 |
|
| 2016 |
Jeon JP, Thakur DP, Tian JB, So I, Zhu MX. Regulator of G protein signaling and GoLoco proteins suppress TRPC4 channel function via acting at Gαi/o. The Biochemical Journal. PMID 26987813 DOI: 10.1042/Bcj20160214 |
0.788 |
|
| 2016 |
Gao L, Yang P, Qin P, Lu Y, Li X, Tian Q, Li Y, Xie C, Tian JB, Zhang C, Tian C, Zhu MX, Yao J. Selective potentiation of 2-APB-induced activation of TRPV1-3 channels by acid. Scientific Reports. 6: 20791. PMID 26876731 DOI: 10.1038/Srep20791 |
0.454 |
|
| 2016 |
Thakur DP, Tian JB, Jeon J, Xiong J, Huang Y, Flockerzi V, Zhu MX. Critical roles of Gi/o proteins and phospholipase C-δ1 in the activation of receptor-operated TRPC4 channels. Proceedings of the National Academy of Sciences of the United States of America. PMID 26755577 DOI: 10.1016/J.Bpj.2015.11.3261 |
0.816 |
|
| 2016 |
Xiong J, Feng X, Zhu MX. Targeting Sequence and Function-Dependence of Subcellular Localization of Transient Receptor Potential Mucolipin Channels Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.3275 |
0.425 |
|
| 2016 |
Jeon J, Thakur DP, Tian JB, Zhu MX. Regulator of G Protein Signaling (RGS) and Goloco Proteins Suppress TRPC4 Channel Function via Acting at GAI/O Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.3262 |
0.451 |
|
| 2016 |
Dryn DO, Gryshchenko AV, Bolton TB, Zhu MX, Zholos AV. Species-Related Differences in the Properties of TRPC4 Channels in Intestinal Myocytes of Rodents Neurophysiology. 48: 220-229. DOI: 10.1007/S11062-016-9592-8 |
0.466 |
|
| 2015 |
Wang YZ, Wang JJ, Huang Y, Liu F, Zeng WZ, Li Y, Xiong ZG, Zhu MX, Xu TL. Tissue acidosis induces neuronal necroptosis via ASIC1a channel independent of its ionic conduction. Elife. 4. PMID 26523449 DOI: 10.7554/Elife.05682 |
0.424 |
|
| 2015 |
Peng Z, Li WG, Huang C, Jiang YM, Wang X, Zhu MX, Cheng X, Xu TL. ASIC3 Mediates Itch Sensation in Response to Coincident Stimulation by Acid and Nonproton Ligand. Cell Reports. PMID 26440887 DOI: 10.1016/J.Celrep.2015.09.002 |
0.437 |
|
| 2015 |
Wong CO, Palmieri M, Li J, Akhmedov D, Chao Y, Broadhead GT, Zhu MX, Berdeaux R, Collins CA, Sardiello M, Venkatachalam K. Diminished MTORC1-Dependent JNK Activation Underlies the Neurodevelopmental Defects Associated with Lysosomal Dysfunction. Cell Reports. PMID 26387958 DOI: 10.1016/J.Celrep.2015.08.047 |
0.312 |
|
| 2015 |
Yang LP, Jiang FJ, Wu GS, Deng K, Wen M, Zhou X, Hong X, Zhu MX, Luo HR. Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice. Plos One. 10: e0136255. PMID 26317356 DOI: 10.1371/Journal.Pone.0136255 |
0.328 |
|
| 2015 |
Cao Q, Zhong XZ, Zou Y, Murrell-Lagnado R, Zhu MX, Dong XP. Calcium release through P2X4 activates calmodulin to promote endolysosomal membrane fusion. The Journal of Cell Biology. 209: 879-94. PMID 26101220 DOI: 10.1083/Jcb.201409071 |
0.455 |
|
| 2015 |
Zhu Y, Lu Y, Qu C, Miller M, Tian J, Thakur DP, Zhu J, Deng Z, Hu X, Wu M, McManus OB, Li M, Hong X, Zhu MX, Luo HR. Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels. British Journal of Pharmacology. 172: 3495-509. PMID 25816897 DOI: 10.1111/Bph.13140 |
0.796 |
|
| 2015 |
Lin PH, Duann P, Komazaki S, Park KH, Li H, Sun M, Sermersheim M, Gumpper K, Parrington J, Galione A, Evans AM, Zhu MX, Ma J. Lysosomal two-pore channel subtype 2 (TPC2) regulates skeletal muscle autophagic signaling. The Journal of Biological Chemistry. 290: 3377-89. PMID 25480788 DOI: 10.1074/Jbc.M114.608471 |
0.327 |
|
| 2015 |
Fu J, Gao Z, Shen B, Zhu MX. Canonical transient receptor potential 4 and its small molecule modulators. Science China. Life Sciences. 58: 39-47. PMID 25480324 DOI: 10.1007/S11427-014-4772-5 |
0.549 |
|
| 2015 |
Venkatachalam K, Wong CO, Zhu MX. The role of TRPMLs in endolysosomal trafficking and function. Cell Calcium. 58: 48-56. PMID 25465891 DOI: 10.1016/J.Ceca.2014.10.008 |
0.491 |
|
| 2015 |
Ogunbayo OA, Zhu Y, Shen B, Agbani E, Li J, Ma J, Zhu MX, Evans AM. Organelle-specific subunit interactions of the vertebrate two-pore channel family. The Journal of Biological Chemistry. 290: 1086-95. PMID 25451935 DOI: 10.1074/Jbc.M114.610493 |
0.438 |
|
| 2014 |
Feng X, Xiong J, Lu Y, Xia X, Zhu MX. Differential mechanisms of action of the mucolipin synthetic agonist, ML-SA1, on insect TRPML and mammalian TRPML1. Cell Calcium. 56: 446-56. PMID 25266962 DOI: 10.1016/J.Ceca.2014.09.004 |
0.443 |
|
| 2014 |
Tian J, Tep C, Benedick A, Saidi N, Ryu JC, Kim ML, Sadasivan S, Oberdick J, Smeyne R, Zhu MX, Yoon SO. p75 regulates Purkinje cell firing by modulating SK channel activity through Rac1. The Journal of Biological Chemistry. 289: 31458-72. PMID 25253694 DOI: 10.1074/Jbc.M114.589937 |
0.425 |
|
| 2014 |
Sun H, Lu L, Zuo Y, Wang Y, Jiao Y, Zeng WZ, Huang C, Zhu MX, Zamponi GW, Zhou T, Xu TL, Cheng J, Li Y. Kainate receptor activation induces glycine receptor endocytosis through PKC deSUMOylation. Nature Communications. 5: 4980. PMID 25236484 DOI: 10.1038/Ncomms5980 |
0.366 |
|
| 2014 |
Huang P, Zou Y, Zhong XZ, Cao Q, Zhao K, Zhu MX, Murrell-Lagnado R, Dong XP. P2X4 forms functional ATP-activated cation channels on lysosomal membranes regulated by luminal pH. The Journal of Biological Chemistry. 289: 17658-67. PMID 24817123 DOI: 10.1074/Jbc.M114.552158 |
0.435 |
|
| 2014 |
Yang P, Zhu MX. TRPV3. Handbook of Experimental Pharmacology. 222: 273-91. PMID 24756710 DOI: 10.1007/978-3-642-54215-2_11 |
0.356 |
|
| 2014 |
Feng X, Huang Y, Lu Y, Xiong J, Wong CO, Yang P, Xia J, Chen D, Du G, Venkatachalam K, Xia X, Zhu MX. Drosophila TRPML forms PI(3,5)P2-activated cation channels in both endolysosomes and plasma membrane. The Journal of Biological Chemistry. 289: 4262-72. PMID 24375408 DOI: 10.1074/Jbc.M113.506501 |
0.431 |
|
| 2014 |
Tian J, Thakur DP, Lu Y, Zhu Y, Freichel M, Flockerzi V, Zhu MX. Dual depolarization responses generated within the same lateral septal neurons by TRPC4-containing channels. Pflugers Archiv : European Journal of Physiology. 466: 1301-16. PMID 24121765 DOI: 10.1007/S00424-013-1362-5 |
0.798 |
|
| 2014 |
Wan X, Lu Y, Chen X, Xiong J, Zhou Y, Li P, Xia B, Li M, Zhu MX, Gao Z. Bimodal voltage dependence of TRPA1: Mutations of a key pore helix residue reveal strong intrinsic voltage-dependent inactivation Pflugers Archiv European Journal of Physiology. 466: 1273-1287. PMID 24092046 DOI: 10.1007/S00424-013-1345-6 |
0.43 |
|
| 2014 |
Thakur D, Zhu MX. Ca2+ Facilitates TRPC4 Activation by Gi/O Signaling in Both Calmodulin Dependent and Independent Manner Biophysical Journal. 106: 755a. DOI: 10.1016/J.Bpj.2013.11.4156 |
0.816 |
|
| 2013 |
Xiao X, Zhu MX, Xu TL. 2-Guanidine-4-methylquinazoline acts as a novel competitive antagonist of A type γ-aminobutyric acid receptors. Neuropharmacology. 75: 126-37. PMID 23916476 DOI: 10.1016/J.Neuropharm.2013.07.018 |
0.392 |
|
| 2013 |
Wang YZ, Zeng WZ, Xiao X, Huang Y, Song XL, Yu Z, Tang D, Dong XP, Zhu MX, Xu TL. Intracellular ASIC1a regulates mitochondrial permeability transition-dependent neuronal death. Cell Death and Differentiation. 20: 1359-69. PMID 23852371 DOI: 10.1038/Cdd.2013.90 |
0.366 |
|
| 2013 |
Feng S, Li H, Tai Y, Huang J, Su Y, Abramowitz J, Zhu MX, Birnbaumer L, Wang Y. Canonical transient receptor potential 3 channels regulate mitochondrial calcium uptake. Proceedings of the National Academy of Sciences of the United States of America. 110: 11011-6. PMID 23776229 DOI: 10.1073/Pnas.1309531110 |
0.586 |
|
| 2013 |
Beck A, Speicher T, Stoerger C, Sell T, Dettmer V, Jusoh SA, Abdulmughni A, Cavalié A, Philipp SE, Zhu MX, Helms V, Wissenbach U, Flockerzi V. Conserved gating elements in TRPC4 and TRPC5 channels. The Journal of Biological Chemistry. 288: 19471-83. PMID 23677990 DOI: 10.1074/Jbc.M113.478305 |
0.495 |
|
| 2013 |
Zeng WZ, Liu DS, Duan B, Song XL, Wang X, Wei D, Jiang W, Zhu MX, Li Y, Xu TL. Molecular mechanism of constitutive endocytosis of Acid-sensing ion channel 1a and its protective function in acidosis-induced neuronal death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 7066-78. PMID 23595764 DOI: 10.1523/Jneurosci.5206-12.2013 |
0.469 |
|
| 2013 |
Tian J, Tep C, Zhu MX, Yoon SO. Changes in Spontaneous firing patterns of cerebellar Purkinje cells in p75 knockout mice. Cerebellum (London, England). 12: 300-3. PMID 23307658 DOI: 10.1007/S12311-012-0439-6 |
0.303 |
|
| 2013 |
Efendiev R, Bavencoffe A, Hu H, Zhu MX, Dessauer CW. Scaffolding by A-kinase anchoring protein enhances functional coupling between adenylyl cyclase and TRPV1 channel. The Journal of Biological Chemistry. 288: 3929-37. PMID 23264624 DOI: 10.1074/Jbc.M112.428144 |
0.429 |
|
| 2012 |
Wang X, Zhang X, Dong XP, Samie M, Li X, Cheng X, Goschka A, Shen D, Zhou Y, Harlow J, Zhu MX, Clapham DE, Ren D, Xu H. TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes. Cell. 151: 372-83. PMID 23063126 DOI: 10.1016/J.Cell.2012.08.036 |
0.474 |
|
| 2012 |
Wang L, Li WG, Huang C, Zhu MX, Xu TL, Wu DZ, Li Y. Subunit-specific inhibition of glycine receptors by curcumol. The Journal of Pharmacology and Experimental Therapeutics. 343: 371-9. PMID 22892339 DOI: 10.1124/Jpet.112.195669 |
0.338 |
|
| 2012 |
Duan B, Liu DS, Huang Y, Zeng WZ, Wang X, Yu H, Zhu MX, Chen ZY, Xu TL. PI3-kinase/Akt pathway-regulated membrane insertion of acid-sensing ion channel 1a underlies BDNF-induced pain hypersensitivity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6351-63. PMID 22553040 DOI: 10.1523/Jneurosci.4479-11.2012 |
0.383 |
|
| 2012 |
Yang Y, Yu Y, Cheng J, Liu Y, Liu DS, Wang J, Zhu MX, Wang R, Xu TL. Highly conserved salt bridge stabilizes rigid signal patch at extracellular loop critical for surface expression of acid-sensing ion channels. The Journal of Biological Chemistry. 287: 14443-55. PMID 22399291 DOI: 10.1074/Jbc.M111.334250 |
0.417 |
|
| 2012 |
Cheng W, Yang F, Liu S, Colton CK, Wang C, Cui Y, Cao X, Zhu MX, Sun C, Wang K, Zheng J. Heteromeric heat-sensitive transient receptor potential channels exhibit distinct temperature and chemical response. The Journal of Biological Chemistry. 287: 7279-88. PMID 22184123 DOI: 10.1074/Jbc.M111.305045 |
0.44 |
|
| 2012 |
Wang X, Zhang X, Dong X, Samie M, Li X, Shen D, Cheng X, Goschka A, Zhou Y, Harlow J, Zhu MX, Clapham DE, Ren D, Xu H. Novel Na+-Selective Channels in the Lysosome Biophysical Journal. 102: 105a. DOI: 10.1016/J.Bpj.2011.11.590 |
0.406 |
|
| 2012 |
Thakur D, Dessauer C, Zhu MX. Differential Modulation of Detergents on Single Channel Activity of TRPC4/C5 Biophysical Journal. 102: 535a-536a. DOI: 10.1016/J.Bpj.2011.11.2926 |
0.818 |
|
| 2012 |
Yang F, Cheng W, Liu S, Colton CK, Wang C, Cui Y, Cao X, Zhu MX, Sun C, Wang K, Zheng J. Heteromeric Heat-Sensitive TRP Channels Exhibit Distinct Temperature and Chemical Response Biophysical Journal. 102: 23a. DOI: 10.1016/J.Bpj.2011.11.153 |
0.448 |
|
| 2011 |
Liu B, Yao J, Zhu MX, Qin F. Hysteresis of gating underlines sensitization of TRPV3 channels. The Journal of General Physiology. 138: 509-20. PMID 22006988 DOI: 10.1085/Jgp.201110689 |
0.537 |
|
| 2011 |
Sarria I, Ling J, Zhu MX, Gu JG. TRPM8 acute desensitization is mediated by calmodulin and requires PIP(2): distinction from tachyphylaxis. Journal of Neurophysiology. 106: 3056-66. PMID 21900509 DOI: 10.1152/Jn.00544.2011 |
0.522 |
|
| 2011 |
Luo J, Zhu Y, Zhu MX, Hu H. Cell-based calcium assay for medium to high throughput screening of TRP channel functions using FlexStation 3. Journal of Visualized Experiments : Jove. PMID 21876521 DOI: 10.3791/3149 |
0.502 |
|
| 2011 |
Gibon J, Tu P, Bohic S, Richaud P, Arnaud J, Zhu M, Boulay G, Bouron A. The over-expression of TRPC6 channels in HEK-293 cells favours the intracellular accumulation of zinc. Biochimica Et Biophysica Acta. 1808: 2807-18. PMID 21864503 DOI: 10.1016/J.Bbamem.2011.08.013 |
0.463 |
|
| 2011 |
Miller M, Shi J, Zhu Y, Kustov M, Tian JB, Stevens A, Wu M, Xu J, Long S, Yang P, Zholos AV, Salovich JM, Weaver CD, Hopkins CR, Lindsley CW, ... ... Zhu MX, et al. Identification of ML204, a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels. The Journal of Biological Chemistry. 286: 33436-46. PMID 21795696 DOI: 10.1074/Jbc.M111.274167 |
0.543 |
|
| 2011 |
Wang SQ, Zhu MX, Carafoli E. Ca2+: a versatile master key for intracellular signaling cascades. Science China. Life Sciences. 54: 683-5. PMID 21786190 DOI: 10.1007/S11427-011-4208-4 |
0.403 |
|
| 2011 |
Duan B, Wang YZ, Yang T, Chu XP, Yu Y, Huang Y, Cao H, Hansen J, Simon RP, Zhu MX, Xiong ZG, Xu TL. Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 2101-12. PMID 21307247 DOI: 10.1523/Jneurosci.4351-10.2011 |
0.404 |
|
| 2011 |
Ogunbayo OA, Zhu Y, Rossi D, Sorrentino V, Ma J, Zhu MX, Evans AM. Cyclic adenosine diphosphate ribose activates ryanodine receptors, whereas NAADP activates two-pore domain channels. The Journal of Biological Chemistry. 286: 9136-40. PMID 21216967 DOI: 10.1074/Jbc.M110.202002 |
0.465 |
|
| 2011 |
Ogunbayo OA, Zhu Y, Agbani E, Evans AM, Zhu MX. Cross-Talk Between Acidic Compartments and the Endoplasmic Reticulum Ca2+ Store Triggered by Ca2+ Release via Two-Pore Segment Channels Biophysical Journal. 100: 82a. DOI: 10.1016/J.Bpj.2010.12.657 |
0.418 |
|
| 2011 |
Pitt SJ, Funnell TM, Zhu MX, Parrington J, Ruas M, Galione A, Sitsapesan R. TPC2 is a Novel NAADP-Sensitive Intracellular Ca2+-Release Channel with Unique Gating Characteristics Biophysical Journal. 100: 433-433. DOI: 10.1016/J.Bpj.2010.12.2557 |
0.509 |
|
| 2010 |
Arredouani A, Evans AM, Ma J, Parrington J, Zhu MX, Galione A. An emerging role for NAADP-mediated Ca2+ signaling in the pancreatic β-cell. Islets. 2: 323-30. PMID 21099331 DOI: 10.4161/Isl.2.5.12747 |
0.333 |
|
| 2010 |
Treves S, Vukcevic M, Griesser J, Armstrong CF, Zhu MX, Zorzato F. Agonist-activated Ca2+ influx occurs at stable plasma membrane and endoplasmic reticulum junctions. Journal of Cell Science. 123: 4170-81. PMID 21062895 DOI: 10.1242/Jcs.068387 |
0.414 |
|
| 2010 |
Pitt SJ, Funnell TM, Sitsapesan M, Venturi E, Rietdorf K, Ruas M, Ganesan A, Gosain R, Churchill GC, Zhu MX, Parrington J, Galione A, Sitsapesan R. TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+. The Journal of Biological Chemistry. 285: 35039-46. PMID 20720007 DOI: 10.1074/Jbc.M110.156927 |
0.511 |
|
| 2010 |
Henderson BJ, Pavlovicz RE, Allen JD, González-Cestari TF, Orac CM, Bonnell AB, Zhu MX, Boyd RT, Li C, Bergmeier SC, McKay DB. Negative allosteric modulators that target human alpha4beta2 neuronal nicotinic receptors. The Journal of Pharmacology and Experimental Therapeutics. 334: 761-74. PMID 20551292 DOI: 10.1124/Jpet.110.168211 |
0.317 |
|
| 2010 |
Zhu MX, Evans AM, Ma J, Parrington J, Galione A. Two-pore channels for integrative Ca signaling. Communicative & Integrative Biology. 3: 12-7. PMID 20539775 DOI: 10.4161/Cib.3.1.9793 |
0.459 |
|
| 2010 |
Ruas M, Rietdorf K, Arredouani A, Davis LC, Lloyd-Evans E, Koegel H, Funnell TM, Morgan AJ, Ward JA, Watanabe K, Cheng X, Churchill GC, Zhu MX, Platt FM, Wessel GM, et al. Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking. Current Biology : Cb. 20: 703-9. PMID 20346675 DOI: 10.1016/J.Cub.2010.02.049 |
0.446 |
|
| 2010 |
Zhu MX, Ma J, Parrington J, Galione A, Evans AM. TPCs: Endolysosomal channels for Ca2+ mobilization from acidic organelles triggered by NAADP. Febs Letters. 584: 1966-74. PMID 20159015 DOI: 10.1016/J.Febslet.2010.02.028 |
0.52 |
|
| 2010 |
Zhu MX, Ma J, Parrington J, Calcraft PJ, Galione A, Evans AM. Calcium signaling via two-pore channels: local or global, that is the question. American Journal of Physiology. Cell Physiology. 298: C430-41. PMID 20018950 DOI: 10.1152/Ajpcell.00475.2009 |
0.341 |
|
| 2010 |
Hu H, Tian J, Zhu Y, Wang C, Xiao R, Herz JM, Wood JD, Zhu MX. Activation of TRPA1 channels by fenamate nonsteroidal anti-inflammatory drugs. Pflã¼Gers Archiv : European Journal of Physiology. 459: 579-92. PMID 19888597 DOI: 10.1007/S00424-009-0749-9 |
0.475 |
|
| 2010 |
Pitt SJ, Funnell T, Zhu MX, Sitsapesan M, Venturi E, Parrington J, Ruas M, Galione A, Sitsapesan R. Luminal Ca2+ is a Major Sensitiser of Two-Pore Channels to NAADP Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.3749 |
0.502 |
|
| 2010 |
Treves S, Griesser J, Franzini-Armstrong C, Zhu M, Zorzato F. Novel Insights into the Role of Junctate in Calcium Homeostasis: Identification of Binding Domain on the InsP3R and Cellular Localization as Determined by TIRF Microscopy Biophysical Journal. 98: 513a. DOI: 10.1016/J.Bpj.2009.12.2790 |
0.356 |
|
| 2010 |
Liu B, Yao J, Zhu MX, Qin F. Sensitization of Vanilloid Receptors TRPV3 Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.1854 |
0.506 |
|
| 2010 |
Xiao R, Tian J, Tang J, Zholos AV, Zhu MX. Critical Role of Pertussis Toxin Sensitive G Proteins in the Activation of TRPC4 and TRPC5 Channels Biophysical Journal. 98: 3-6. DOI: 10.1016/J.Bpj.2009.12.1770 |
0.515 |
|
| 2009 |
Gross SA, Guzmán GA, Wissenbach U, Philipp SE, Zhu MX, Bruns D, Cavalié A. TRPC5 is a Ca2+-activated channel functionally coupled to Ca2+-selective ion channels Journal of Biological Chemistry. 284: 34423-34432. PMID 19815560 DOI: 10.1074/Jbc.M109.018192 |
0.5 |
|
| 2009 |
Tsvilovskyy VV, Zholos AV, Aberle T, Philipp SE, Dietrich A, Zhu MX, Birnbaumer L, Freichel M, Flockerzi V. Deletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo. Gastroenterology. 137: 1415-24. PMID 19549525 DOI: 10.1053/J.Gastro.2009.06.046 |
0.693 |
|
| 2009 |
Galione A, Evans AM, Ma J, Parrington J, Arredouani A, Cheng X, Zhu MX. The acid test: the discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca(2+) release channels. PflüGers Archiv : European Journal of Physiology. 458: 869-76. PMID 19475418 DOI: 10.1007/S00424-009-0682-Y |
0.517 |
|
| 2009 |
Calcraft PJ, Ruas M, Pan Z, Cheng X, Arredouani A, Hao X, Tang J, Rietdorf K, Teboul L, Chuang KT, Lin P, Xiao R, Wang C, Zhu Y, Lin Y, ... ... Zhu MX, et al. NAADP mobilizes calcium from acidic organelles through two-pore channels. Nature. 459: 596-600. PMID 19387438 DOI: 10.1038/Nature08030 |
0.469 |
|
| 2009 |
Liao Y, Plummer NW, George MD, Abramowitz J, Zhu MX, Birnbaumer L. A role for Orai in TRPC-mediated Ca2+ entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca2+ entry. Proceedings of the National Academy of Sciences of the United States of America. 106: 3202-6. PMID 19221033 DOI: 10.1073/Pnas.0813346106 |
0.63 |
|
| 2009 |
Hu H, Bandell M, Petrus MJ, Zhu MX, Patapoutian A. Zinc activates damage-sensing TRPA1 ion channels. Nature Chemical Biology. 5: 183-90. PMID 19202543 DOI: 10.1038/Nchembio.146 |
0.461 |
|
| 2009 |
Sidiropoulou K, Lu FM, Fowler MA, Xiao R, Phillips C, Ozkan ED, Zhu MX, White FJ, Cooper DC. Dopamine modulates an mGluR5-mediated depolarization underlying prefrontal persistent activity. Nature Neuroscience. 12: 190-9. PMID 19169252 DOI: 10.1038/Nn.2245 |
0.32 |
|
| 2009 |
González-Cestari TF, Henderson BJ, Pavlovicz RE, McKay SB, El-Hajj RA, Pulipaka AB, Orac CM, Reed DD, Boyd RT, Zhu MX, Li C, Bergmeier SC, McKay DB. Effect of novel negative allosteric modulators of neuronal nicotinic receptors on cells expressing native and recombinant nicotinic receptors: implications for drug discovery. The Journal of Pharmacology and Experimental Therapeutics. 328: 504-15. PMID 18984653 DOI: 10.1124/Jpet.108.144576 |
0.327 |
|
| 2009 |
Iscru E, Serinagaoglu Y, Schilling K, Tian J, Bowers-Kidder SL, Zhang R, Morgan JI, DeVries AC, Nelson RJ, Zhu MX, Oberdick J. Sensorimotor enhancement in mouse mutants lacking the Purkinje cell-specific Gi/o modulator, Pcp2(L7). Molecular and Cellular Neurosciences. 40: 62-75. PMID 18930827 DOI: 10.1016/J.Mcn.2008.09.002 |
0.367 |
|
| 2009 |
Calcraft PJ, Arredouani A, Pan Z, Cheng X, Tang J, Ruas M, Rietdorf K, Lin P, Parrington J, Ma J, Evans AM, Galione A, Zhu MX. Two-pore Channels for Calcium Mobilization from Acidic Organelles and Cell Signaling by NAADP Biophysical Journal. 96: 391a. DOI: 10.1016/J.Bpj.2008.12.2916 |
0.525 |
|
| 2008 |
Liao Y, Erxleben C, Abramowitz J, Flockerzi V, Zhu MX, Armstrong DL, Birnbaumer L. Functional interactions among Orai1, TRPCs, and STIM1 suggest a STIM-regulated heteromeric Orai/TRPC model for SOCE/Icrac channels. Proceedings of the National Academy of Sciences of the United States of America. 105: 2895-900. PMID 18287061 DOI: 10.1073/Pnas.0712288105 |
0.659 |
|
| 2008 |
Otsuguro K, Tang J, Tang Y, Xiao R, Freichel M, Tsvilovskyy V, Ito S, Flockerzi V, Zhu MX, Zholos AV. Isoform-specific inhibition of TRPC4 channel by phosphatidylinositol 4,5-bisphosphate. The Journal of Biological Chemistry. 283: 10026-36. PMID 18230622 DOI: 10.1074/Jbc.M707306200 |
0.553 |
|
| 2008 |
Xiao R, Tang J, Wang C, Colton CK, Tian J, Zhu MX. Calcium plays a central role in the sensitization of TRPV3 channel to repetitive stimulations. The Journal of Biological Chemistry. 283: 6162-74. PMID 18178557 DOI: 10.1074/Jbc.M706535200 |
0.518 |
|
| 2008 |
Xiao R, Tian J, Tang J, Zhu MX. The TRPV3 mutation associated with the hairless phenotype in rodents is constitutively active. Cell Calcium. 43: 334-43. PMID 17706768 DOI: 10.1016/J.Ceca.2007.06.004 |
0.411 |
|
| 2007 |
Xu M, Cao R, Xiao R, Zhu MX, Gu C. The axon-dendrite targeting of Kv3 (Shaw) channels is determined by a targeting motif that associates with the T1 domain and ankyrin G. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 14158-70. PMID 18094255 DOI: 10.1523/Jneurosci.3675-07.2007 |
0.363 |
|
| 2007 |
Zhu MX. Understanding the role of voltage gating of polymodal TRP channels. The Journal of Physiology. 585: 321-2. PMID 18056113 DOI: 10.1113/Jphysiol.2007.147082 |
0.409 |
|
| 2006 |
Hu HZ, Xiao R, Wang C, Gao N, Colton CK, Wood JD, Zhu MX. Potentiation of TRPV3 channel function by unsaturated fatty acids. Journal of Cellular Physiology. 208: 201-12. PMID 16557504 DOI: 10.1002/Jcp.20648 |
0.476 |
|
| 2006 |
Poteser M, Graziani A, Rosker C, Eder P, Derler I, Kahr H, Zhu MX, Romanin C, Groschner K. TRPC3 and TRPC4 associate to form a redox-sensitive cation channel. Evidence for expression of native TRPC3-TRPC4 heteromeric channels in endothelial cells. The Journal of Biological Chemistry. 281: 13588-95. PMID 16537542 DOI: 10.1074/Jbc.M512205200 |
0.468 |
|
| 2006 |
Ni D, Gu Q, Hu HZ, Gao N, Zhu MX, Lee LY. Thermal sensitivity of isolated vagal pulmonary sensory neurons: role of transient receptor potential vanilloid receptors. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 291: R541-50. PMID 16513770 DOI: 10.1152/Ajpregu.00016.2006 |
0.381 |
|
| 2006 |
Graziani A, Rosker C, Kohlwein SD, Zhu MX, Romanin C, Sattler W, Groschner K, Poteser M. Cellular cholesterol controls TRPC3 function: evidence from a novel dominant-negative knockdown strategy. The Biochemical Journal. 396: 147-55. PMID 16448384 DOI: 10.1042/Bj20051246 |
0.427 |
|
| 2005 |
Cioffi DL, Wu S, Alexeyev M, Goodman SR, Zhu MX, Stevens T. Activation of the endothelial store-operated ISOC Ca2+ channel requires interaction of protein 4.1 with TRPC4. Circulation Research. 97: 1164-72. PMID 16254212 DOI: 10.1161/01.Res.0000193597.65217.00 |
0.533 |
|
| 2005 |
Ordaz B, Tang J, Xiao R, Salgado A, Sampieri A, Zhu MX, Vaca L. Calmodulin and calcium interplay in the modulation of TRPC5 channel activity. Identification of a novel C-terminal domain for calcium/calmodulin-mediated facilitation. The Journal of Biological Chemistry. 280: 30788-96. PMID 15987684 DOI: 10.1074/Jbc.M504745200 |
0.558 |
|
| 2005 |
Zhu MX. Multiple roles of calmodulin and other Ca 2+ -binding proteins in the functional regulation of TRP channels PflüGers Archiv: European Journal of Physiology. 451: 105-115. PMID 15924238 DOI: 10.1007/S00424-005-1427-1 |
0.502 |
|
| 2005 |
Kinoshita-Kawada M, Tang J, Xiao R, Kaneko S, Foskett JK, Zhu MX. Inhibition of TRPC5 channels by Ca2+-binding protein 1 in Xenopus oocytes. PflüGers Archiv : European Journal of Physiology. 450: 345-54. PMID 15895247 DOI: 10.1007/S00424-005-1419-1 |
0.553 |
|
| 2005 |
Nilius B, Prenen J, Janssens A, Owsianik G, Wang C, Zhu MX, Voets T. The selectivity filter of the cation channel TRPM4. The Journal of Biological Chemistry. 280: 22899-906. PMID 15845551 DOI: 10.1074/Jbc.M501686200 |
0.5 |
|
| 2005 |
Gu Q, Lin RL, Hu HZ, Zhu MX, Lee LY. 2-aminoethoxydiphenyl borate stimulates pulmonary C neurons via the activation of TRPV channels. American Journal of Physiology. Lung Cellular and Molecular Physiology. 288: L932-41. PMID 15653710 DOI: 10.1152/Ajplung.00439.2004 |
0.36 |
|
| 2005 |
Nilius B, Prenen J, Tang J, Wang C, Owsianik G, Janssens A, Voets T, Zhu MX. Regulation of the Ca2+ sensitivity of the nonselective cation channel TRPM4. The Journal of Biological Chemistry. 280: 6423-33. PMID 15590641 DOI: 10.1074/Jbc.M411089200 |
0.455 |
|
| 2004 |
Tseng PH, Lin HP, Hu H, Wang C, Zhu MX, Chen CS. The canonical transient receptor potential 6 channel as a putative phosphatidylinositol 3,4,5-trisphosphate-sensitive calcium entry system. Biochemistry. 43: 11701-8. PMID 15362854 DOI: 10.1021/Bi049349F |
0.457 |
|
| 2004 |
Treves S, Franzini-Armstrong C, Moccagatta L, Arnoult C, Grasso C, Schrum A, Ducreux S, Zhu MX, Mikoshiba K, Girard T, Smida-Rezgui S, Ronjat M, Zorzato F. Junctate is a key element in calcium entry induced by activation of InsP3 receptors and/or calcium store depletion. The Journal of Cell Biology. 166: 537-48. PMID 15302852 DOI: 10.1083/Jcb.200404079 |
0.394 |
|
| 2004 |
Wang C, Hu HZ, Colton CK, Wood JD, Zhu MX. An alternative splicing product of the murine trpv1 gene dominant negatively modulates the activity of TRPV1 channels. The Journal of Biological Chemistry. 279: 37423-30. PMID 15234965 DOI: 10.1074/Jbc.M407205200 |
0.49 |
|
| 2004 |
Hu HZ, Gu Q, Wang C, Colton CK, Tang J, Kinoshita-Kawada M, Lee LY, Wood JD, Zhu MX. 2-aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3. The Journal of Biological Chemistry. 279: 35741-8. PMID 15194687 DOI: 10.1074/Jbc.M404164200 |
0.465 |
|
| 2004 |
Zhu MX, Tang J. TRPC channel interactions with calmodulin and IP3 receptors. Novartis Foundation Symposium. 258: 44-58; discussion 58. PMID 15104175 |
0.405 |
|
| 2004 |
Rosker C, Graziani A, Lukas M, Eder P, Zhu MX, Romanin C, Groschner K. Ca2+ signaling by TRPC3 involves Na+ entry and local coupling to the Na+/Ca2+ exchanger Journal of Biological Chemistry. 279: 13696-13704. PMID 14736881 DOI: 10.1074/Jbc.M308108200 |
0.438 |
|
| 2003 |
Hu HZ, Gao N, Zhu MX, Liu S, Ren J, Gao C, Xia Y, Wood JD. Slow excitatory synaptic transmission mediated by P2Y1 receptors in the guinea-pig enteric nervous system. The Journal of Physiology. 550: 493-504. PMID 12807993 DOI: 10.1113/Jphysiol.2003.041731 |
0.354 |
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| 2002 |
Zhang B, Ma X, Yeh C, Lifschitz MD, Zhu MX, Katz MS. EGF induced depletion of the intracellular Ca2+ store fails to activate capacitative Ca2+ entry in a human salivary cell line Journal of Biological Chemistry. 277: 48165-71. PMID 12368284 DOI: 10.1074/Jbc.M208077200 |
0.389 |
|
| 2002 |
Hassock SR, Zhu MX, Trost C, Flockerzi V, Authi KS. Expression and role of TRPC proteins in human platelets: evidence that TRPC6 forms the store-independent calcium entry channel. Blood. 100: 2801-2811. PMID 12351388 DOI: 10.1182/Blood-2002-03-0723 |
0.485 |
|
| 2002 |
Singh BB, Liu X, Tang J, Zhu MX, Ambudkar IS. Calmodulin regulates Ca(2+)-dependent feedback inhibition of store-operated Ca(2+) influx by interaction with a site in the C terminus of TrpC1. Molecular Cell. 9: 739-50. PMID 11983166 DOI: 10.1016/S1097-2765(02)00506-3 |
0.408 |
|
| 2002 |
Montell C, Birnbaumer L, Flockerzi V, Bindels RJ, Bruford EA, Caterina MJ, Clapham DE, Harteneck C, Heller S, Julius D, Kojima I, Mori Y, Penner R, Prawitt D, Scharenberg AM, ... ... Zhu MX, et al. A unified nomenclature for the superfamily of TRP cation channels. Molecular Cell. 9: 229-31. PMID 11864597 DOI: 10.1016/S1097-2765(02)00448-3 |
0.674 |
|
| 2001 |
Singh BB, Zheng C, Liu X, Lockwich T, Liao D, Zhu MX, Birnbaumer L, Ambudkar IS. Trp1-dependent enhancement of salivary gland fluid secretion: role of store-operated calcium entry. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1652-4. PMID 11427516 DOI: 10.1096/Fj.00-0749Fje |
0.574 |
|
| 2001 |
Tang J, Lin Y, Zhang Z, Tikunova S, Birnbaumer L, Zhu MX. Identification of common binding sites for calmodulin and inositol 1,4,5-trisphosphate receptors on the carboxyl termini of trp channels. The Journal of Biological Chemistry. 276: 21303-10. PMID 11290752 DOI: 10.1074/Jbc.M102316200 |
0.579 |
|
| 2001 |
Zhang Z, Tang J, Tikunova S, Johnson JD, Chen Z, Qin N, Dietrich A, Stefani E, Birnbaumer L, Zhu MX. Activation of Trp3 by inositol 1,4,5-trisphosphate receptors through displacement of inhibitory calmodulin from a common binding domain. Proceedings of the National Academy of Sciences of the United States of America. 98: 3168-73. PMID 11248050 DOI: 10.1073/Pnas.051632698 |
0.685 |
|
| 2001 |
Zhang Z, Tang Y, Zhu MX. Increased inwardly rectifying potassium currents in HEK-293 cells expressing murine transient receptor potential 4. Biochemical Journal. 354: 717-725. PMID 11237877 DOI: 10.1042/0264-6021:3540717 |
0.443 |
|
| 2000 |
Tang Y, Tang J, Chen Z, Trost C, Flockerzi V, Li M, Ramesh V, Zhu MX. Association of Mammalian Trp4 and Phospholipase C Isozymes with a PDZ Domain-containing Protein, NHERF Journal of Biological Chemistry. 275: 37559-37564. PMID 10980202 DOI: 10.1074/Jbc.M006635200 |
0.461 |
|
| 2000 |
Lintschinger B, Balzer-Geldsetzer M, Baskaran T, Graier WF, Romanin C, Zhu MX, Groschner K. Coassembly of Trp1 and Trp3 proteins generates diacylglycerol- and Ca2+-sensitive cation channels. Journal of Biological Chemistry. 275: 27799-27805. PMID 10882720 DOI: 10.1074/Jbc.M002705200 |
0.506 |
|
| 2000 |
Liu X, Wang W, Singh BB, Lockwich T, Jadlowiec J, O'Connell B, Wellner R, Zhu MX, Ambudkar IS. Trp1, a candidate protein for the store-operated Ca(2+) influx mechanism in salivary gland cells. The Journal of Biological Chemistry. 275: 3403-11. PMID 10652333 DOI: 10.1074/Jbc.275.5.3403 |
0.446 |
|
| 1999 |
Boulay G, Brown DM, Qin N, Jiang M, Dietrich A, Zhu MX, Chen Z, Birnbaumer M, Mikoshiba K, Birnbaumer L. Modulation of Ca(2+) entry by polypeptides of the inositol 1,4, 5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): evidence for roles of TRP and IP3R in store depletion-activated Ca(2+) entry. Proceedings of the National Academy of Sciences of the United States of America. 96: 14955-60. PMID 10611319 DOI: 10.1073/Pnas.96.26.14955 |
0.783 |
|
| 1999 |
Kiselyov K, Mignery GA, Zhu MX, Muallem S. The N-terminal domain of the IP3 receptor gates store-operated hTrp3 channels. Molecular Cell. 4: 423-9. PMID 10518223 DOI: 10.1016/S1097-2765(00)80344-5 |
0.488 |
|
| 1999 |
Li H, Lin Y, Heath RM, Zhu MX, Yang Z. Control of Pollen Tube Tip Growth by a Rop GTPase–Dependent Pathway That Leads to Tip-Localized Calcium Influx The Plant Cell. 11: 1731-1742. PMID 10488239 DOI: 10.1105/Tpc.11.9.1731 |
0.345 |
|
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