Karin Danzer - Publications

Affiliations: 
2008-2011 Neurology Massachusetts General Hospital, Boston, MA 

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Grozdanov V, Danzer KM. Intracellular Alpha-Synuclein and Immune Cell Function. Frontiers in Cell and Developmental Biology. 8: 562692. PMID 33178682 DOI: 10.3389/fcell.2020.562692  0.348
2020 Kiechle M, Grozdanov V, Danzer KM. The Role of Lipids in the Initiation of α-Synuclein Misfolding. Frontiers in Cell and Developmental Biology. 8: 562241. PMID 33042996 DOI: 10.3389/fcell.2020.562241  0.412
2019 Kiechle M, von Einem B, Höfs L, Voehringer P, Grozdanov V, Markx D, Parlato R, Wiesner D, Mayer B, Sakk O, Baumann B, Lukassen S, Liss B, Ekici AB, Ludolph AC, ... ... Danzer KM, et al. In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8-16-mer Oligomer Species. Cell Reports. 29: 2862-2874.e9. PMID 31775051 DOI: 10.1016/J.Celrep.2019.10.089  0.682
2019 Grozdanov V, Bousset L, Hoffmeister M, Bliederhaeuser C, Meier C, Madiona K, Pieri L, Kiechle M, McLean PJ, Kassubek J, Behrends C, Ludolph AC, Weishaupt JH, Melki R, Danzer KM. Increased immune activation by pathologic alpha-synuclein in Parkinson's Disease. Annals of Neurology. PMID 31343083 DOI: 10.1002/Ana.25557  0.671
2018 Grozdanov V, Danzer KM. Release and uptake of pathologic alpha-synuclein. Cell and Tissue Research. PMID 29411106 DOI: 10.1007/s00441-017-2775-9  0.436
2017 Zondler L, Kostka M, Garidel P, Heinzelmann U, Hengerer B, Mayer B, Weishaupt JH, Gillardon F, Danzer KM. Proteasome impairment by α-synuclein. Plos One. 12: e0184040. PMID 28945746 DOI: 10.1371/journal.pone.0184040  0.456
2017 von Einem B, Eschbach J, Kiechle M, Wahler A, Thal DR, McLean PJ, Weishaupt JH, Ludolph AC, von Arnim CAF, Danzer KM. The Golgi-localized, gamma ear-containing, ARF-binding (GGA) protein family alters alpha synuclein (α-syn) oligomerization and secretion. Aging. PMID 28722658 DOI: 10.18632/aging.101261  0.694
2016 Helferich AM, McLean PJ, Weishaupt JH, Danzer KM. Commentary: alpha-synuclein interacts with SOD1 and promotes its oligomerization. Journal of Neurology & Neuromedicine. 1: 28-30. PMID 27853754  0.684
2016 Koch Y, Helferich AM, Steinacker P, Oeckl P, Walther P, Weishaupt JH, Danzer KM, Otto M. Aggregated α-Synuclein Increases SOD1 Oligomerization in a Mouse Model of Amyotrophic Lateral Sclerosis. The American Journal of Pathology. 186: 2152-2161. PMID 27322773 DOI: 10.1016/j.ajpath.2016.04.008  0.387
2015 Stuendl A, Kunadt M, Kruse N, Bartels C, Moebius W, Danzer KM, Mollenhauer B, Schneider A. Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson's disease and dementia with Lewy bodies. Brain : a Journal of Neurology. PMID 26647156 DOI: 10.1093/brain/awv346  0.432
2015 Helferich AM, Ruf WP, Grozdanov V, Freischmidt A, Feiler MS, Zondler L, Ludolph AC, McLean PJ, Weishaupt JH, Danzer KM. α-synuclein interacts with SOD1 and promotes its oligomerization. Molecular Neurodegeneration. 10: 66. PMID 26643113 DOI: 10.1186/S13024-015-0062-3  0.688
2015 Bliederhaeuser C, Grozdanov V, Speidel A, Zondler L, Ruf WP, Bayer H, Kiechle M, Feiler MS, Freischmidt A, Brenner D, Witting A, Hengerer B, Fändrich M, Ludolph AC, Weishaupt JH, ... ... Danzer KM, et al. Age-dependent defects of alpha-synuclein oligomer uptake in microglia and monocytes. Acta Neuropathologica. PMID 26576561 DOI: 10.1007/s00401-015-1504-2  0.37
2015 von Einem B, Wahler A, Schips T, Serrano-Pozo A, Proepper C, Boeckers TM, Rueck A, Wirth T, Hyman BT, Danzer KM, Thal DR, von Arnim CA. The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1). Plos One. 10: e0129047. PMID 26053850 DOI: 10.1371/Journal.Pone.0129047  0.32
2015 Kunadt M, Eckermann K, Stuendl A, Gong J, Russo B, Strauss K, Rai S, Kügler S, Falomir Lockhart L, Schwalbe M, Krumova P, Oliveira LM, Bähr M, Möbius W, Levin J, ... ... Danzer KM, et al. Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation. Acta Neuropathologica. 129: 695-713. PMID 25778619 DOI: 10.1007/S00401-015-1408-1  0.3
2015 Eschbach J, von Einem B, Müller K, Bayer H, Scheffold A, Morrison BE, Rudolph KL, Thal DR, Witting A, Weydt P, Otto M, Fauler M, Liss B, McLean PJ, Spada AR, ... ... Danzer KM, et al. Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization. Annals of Neurology. 77: 15-32. PMID 25363075 DOI: 10.1002/Ana.24294  0.666
2014 Lázaro DF, Rodrigues EF, Langohr R, Shahpasandzadeh H, Ribeiro T, Guerreiro P, Gerhardt E, Kröhnert K, Klucken J, Pereira MD, Popova B, Kruse N, Mollenhauer B, Rizzoli SO, Braus GH, ... Danzer KM, et al. Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation. Plos Genetics. 10: e1004741. PMID 25393002 DOI: 10.1371/Journal.Pgen.1004741  0.436
2014 McFarland NR, Dimant H, Kibuuka L, Ebrahimi-Fakhari D, Desjardins CA, Danzer KM, Danzer M, Fan Z, Schwarzschild MA, Hirst W, McLean PJ. Chronic treatment with novel small molecule Hsp90 inhibitors rescues striatal dopamine levels but not α-synuclein-induced neuronal cell loss. Plos One. 9: e86048. PMID 24465863 DOI: 10.1371/Journal.Pone.0086048  0.771
2014 Eschbach J, Danzer KM. α-Synuclein in Parkinson's disease: pathogenic function and translation into animal models. Neuro-Degenerative Diseases. 14: 1-17. PMID 24080741 DOI: 10.1159/000354615  0.432
2012 Danzer KM, Kranich LR, Ruf WP, Cagsal-Getkin O, Winslow AR, Zhu L, Vanderburg CR, McLean PJ. Exosomal cell-to-cell transmission of alpha synuclein oligomers. Molecular Neurodegeneration. 7: 42. PMID 22920859 DOI: 10.1186/1750-1326-7-42  0.818
2011 Vlad C, Lindner K, Karreman C, Schildknecht S, Leist M, Tomczyk N, Rontree J, Langridge J, Danzer K, Ciossek T, Petre A, Gross ML, Hengerer B, Przybylski M. Autoproteolytic fragments are intermediates in the oligomerization/aggregation of the Parkinson's disease protein alpha-synuclein as revealed by ion mobility mass spectrometry. Chembiochem : a European Journal of Chemical Biology. 12: 2740-4. PMID 22162214 DOI: 10.1002/Cbic.201100569  0.316
2011 Danzer KM, McLean PJ. Drug targets from genetics: α-synuclein. Cns & Neurological Disorders Drug Targets. 10: 712-23. PMID 21838671 DOI: 10.2174/187152711797247867  0.697
2011 Welander H, Bontha SV, Näsström T, Karlsson M, Nikolajeff F, Danzer K, Kostka M, Kalimo H, Lannfelt L, Ingelsson M, Bergström J. Gelsolin co-occurs with Lewy bodies in vivo and accelerates α-synuclein aggregation in vitro. Biochemical and Biophysical Research Communications. 412: 32-8. PMID 21798243 DOI: 10.1016/J.Bbrc.2011.07.027  0.453
2011 Danzer KM, Ruf WP, Putcha P, Joyner D, Hashimoto T, Glabe C, Hyman BT, McLean PJ. Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 326-36. PMID 20876215 DOI: 10.1096/Fj.10-164624  0.725
2010 Putcha P, Danzer KM, Kranich LR, Scott A, Silinski M, Mabbett S, Hicks CD, Veal JM, Steed PM, Hyman BT, McLean PJ. Brain-permeable small-molecule inhibitors of Hsp90 prevent alpha-synuclein oligomer formation and rescue alpha-synuclein-induced toxicity. The Journal of Pharmacology and Experimental Therapeutics. 332: 849-57. PMID 19934398 DOI: 10.1124/Jpet.109.158436  0.703
2009 Danzer KM, Krebs SK, Wolff M, Birk G, Hengerer B. Seeding induced by alpha-synuclein oligomers provides evidence for spreading of alpha-synuclein pathology. Journal of Neurochemistry. 111: 192-203. PMID 19686384 DOI: 10.1111/j.1471-4159.2009.06324.x  0.409
2008 Kostka M, Högen T, Danzer KM, Levin J, Habeck M, Wirth A, Wagner R, Glabe CG, Finger S, Heinzelmann U, Garidel P, Duan W, Ross CA, Kretzschmar H, Giese A. Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers. The Journal of Biological Chemistry. 283: 10992-1003. PMID 18258594 DOI: 10.1074/Jbc.M709634200  0.368
2007 Danzer KM, Schnack C, Sutcliffe A, Hengerer B, Gillardon F. Functional protein kinase arrays reveal inhibition of p-21-activated kinase 4 by alpha-synuclein oligomers. Journal of Neurochemistry. 103: 2401-7. PMID 17883396 DOI: 10.1111/j.1471-4159.2007.04933.x  0.389
2007 Danzer KM, Haasen D, Karow AR, Moussaud S, Habeck M, Giese A, Kretzschmar H, Hengerer B, Kostka M. Different species of alpha-synuclein oligomers induce calcium influx and seeding. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9220-32. PMID 17715357 DOI: 10.1523/JNEUROSCI.2617-07.2007  0.808
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