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Beisi Xu, Ph.D - Publications

Affiliations: 
2011-2014 City of Hope Medical Center, Duarte, CA, United States 
 2014- Center for Applied Bioinformatics St Jude Children's Research Hospital, New York, NY, United States 
Website:
https://www.ncbi.nlm.nih.gov/myncbi/1zofdYmKS0FQg/bibliography/public/

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Barajas JM, Rasouli M, Umeda M, Hiltenbrand RL, Abdelhamed S, Mohnani R, Arthur B, Westover T, Thomas ME, Ashtiani M, Janke LJ, Xu B, Chang TC, Rosikiewicz W, Xiong E, et al. Acute myeloid leukemias with UBTF tandem duplications are sensitive to Menin inhibitors. Blood. PMID 37890156 DOI: 10.1182/blood.2023021359  0.327
2023 Klco J, Thomas M, Qi W, Walsh M, Ma J, Westover T, Abdelhamed S, Ezzell L, Rolle C, Xiong E, Rosikiewicz W, Xu B, Pruett-Miller S, Loughran A, Janke L. Functional Characterization of Cooperating MGA Mutations in RUNX1::RUNX1T1 Acute Myeloid Leukemia. Research Square. PMID 37790524 DOI: 10.21203/rs.3.rs-3315059/v1  0.749
2023 Matsui Y, Djekidel MN, Lindsay K, Samir P, Connolly N, Wu G, Yang X, Fan Y, Xu B, Peng JC. SNIP1 and PRC2 coordinate cell fates of neural progenitors during brain development. Nature Communications. 14: 4754. PMID 37553330 DOI: 10.1038/s41467-023-40487-4  0.714
2023 Lim B, Djekidel MN, Matsui Y, Jung S, Yuan ZF, Wang X, Yang X, Pilehroud AS, Pan H, Wang F, Pruett-Miller S, Kavdia K, Pagala V, Fan Y, Peng J, ... Xu B, et al. Phosphorylation of 53BP1 by ATM enforce neurodevelopmental programs in cortical organoids. Biorxiv : the Preprint Server For Biology. PMID 37205560 DOI: 10.1101/2023.05.04.539457  0.721
2023 Wright S, Hu J, Wang H, Hyle J, Zhang Y, Du G, Konopleva MY, Kornblau SM, Djekidel MN, Rosikiewicz W, Xu B, Lu R, Yang JJ, Li C. Interrogating bromodomain inhibitor resistance in KMT2A-rearranged leukemia through combinatorial CRISPR screens. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220134120. PMID 37036970 DOI: 10.1073/pnas.2220134120  0.723
2023 Hyle J, Djekidel MN, Williams J, Wright S, Shao Y, Xu B, Li C. Auxin-inducible degron 2 system deciphers functions of CTCF domains in transcriptional regulation. Genome Biology. 24: 14. PMID 36698211 DOI: 10.1186/s13059-022-02843-3  0.734
2023 Wang R, Bhatt AB, Minden-Birkenmaier BA, Travis OK, Tiwari S, Jia H, Rosikiewicz W, Martinot O, Childs E, Loesch R, Tossou G, Jamieson S, Finkelstein D, Xu B, Labelle M. ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis. Science Advances. 9: eabq3951. PMID 36608120 DOI: 10.1126/sciadv.abq3951  0.736
2022 Zhao X, Wang P, Diedrich JD, Smart B, Reyes N, Yoshimura S, Zhang J, Yang W, Barnett K, Xu B, Li Z, Huang X, Yu J, Crews K, Yeoh AEJ, et al. Epigenetic activation of the FLT3 gene by ZNF384 fusion confers a therapeutic susceptibility in acute lymphoblastic leukemia. Nature Communications. 13: 5401. PMID 36104354 DOI: 10.1038/s41467-022-33143-w  0.324
2022 Wang X, Rosikiewicz W, Sedkov Y, Mondal B, Martinez T, Kallappagoudar S, Tvardovskiy A, Bajpai R, Xu B, Pruett-Miller SM, Schneider R, Herz HM. The MLL3/4 complexes and MiDAC co-regulate H4K20ac to control a specific gene expression program. Life Science Alliance. 5. PMID 35820704 DOI: 10.26508/lsa.202201572  0.736
2022 Drosos Y, Myers JA, Xu B, Mathias KM, Beane EC, Radko-Juettner S, Mobley RJ, Larsen ME, Piccioni F, Ma X, Low J, Hansen BS, Peters ST, Bhanu NV, Dhanda SK, et al. NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition. Molecular Cell. PMID 35537449 DOI: 10.1016/j.molcel.2022.04.015  0.32
2022 Qi W, Rosikiewicz W, Yin Z, Xu B, Jiang H, Wan S, Fan Y, Wu G, Wang L. Genomic profiling identifies genes and pathways dysregulated by HEY1-NCOA2 fusion and shines a light on mesenchymal chondrosarcoma tumorigenesis. The Journal of Pathology. PMID 35342947 DOI: 10.1002/path.5899  0.74
2022 Wang X, Rosikiewicz W, Sedkov Y, Martinez T, Hansen BS, Schreiner P, Christensen J, Xu B, Pruett-Miller SM, Helin K, Herz HM. PROSER1 mediates TET2 O-GlcNAcylation to regulate DNA demethylation on UTX-dependent enhancers and CpG islands. Life Science Alliance. 5. PMID 34667079 DOI: 10.26508/lsa.202101228  0.733
2021 Li J, Xu B, He M, Zong X, Cunningham T, Sha C, Fan Y, Cross R, Hanna JH, Feng Y. Control of Foxp3 induction and maintenance by sequential histone acetylation and DNA demethylation. Cell Reports. 37: 110124. PMID 34910919 DOI: 10.1016/j.celrep.2021.110124  0.311
2021 D'Oto A, Fang J, Jin H, Xu B, Singh S, Mullasseril A, Jones V, Abu-Zaid A, von Buttlar X, Cooke B, Hu D, Shohet J, Murphy AJ, Davidoff AM, Yang J. KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma. Nature Communications. 12: 7204. PMID 34893606 DOI: 10.1038/s41467-021-27502-2  0.334
2021 Li H, Dong H, Xu B, Xiong QP, Li CT, Yang WQ, Li J, Huang ZX, Zeng QY, Wang ED, Liu RJ. A dual role of human tRNA methyltransferase hTrmt13 in regulating translation and transcription. The Embo Journal. e108544. PMID 34850409 DOI: 10.15252/embj.2021108544  0.305
2021 Xu B, Wang H, Wright S, Hyle J, Zhang Y, Shao Y, Niu M, Fan Y, Rosikiewicz W, Djekidel MN, Peng J, Lu R, Li C. Acute depletion of CTCF rewires genome-wide chromatin accessibility. Genome Biology. 22: 244. PMID 34429148 DOI: 10.1186/s13059-021-02466-0  0.744
2021 Djekidel MN, Rosikiewicz W, Peng JC, Kanneganti TD, Hui Y, Jin H, Hedges D, Schreiner P, Fan Y, Wu G, Xu B. CovidExpress: an interactive portal for intuitive investigation on SARS-CoV-2 related transcriptomes. Biorxiv : the Preprint Server For Biology. PMID 34075382 DOI: 10.1101/2021.05.14.444026  0.728
2020 Xu P, Scott DC, Xu B, Yao Y, Feng R, Cheng L, Mayberry K, Bi W, Palmer LE, King MT, Wang H, Li Y, Fan Y, Alpi AF, Li C, et al. FBXO11-Mediated Proteolysis of BAHD1 Relieves PRC2-dependent Transcriptional Repression in Erythropoiesis. Blood. PMID 33156908 DOI: 10.1182/blood.2020007809  0.36
2020 Zhang H, Zhang Y, Zhou X, Wright S, Hyle J, Zhao L, An J, Zhao X, Shao Y, Xu B, Lee HM, Chen T, Zhou Y, Chen X, Lu R, et al. Functional interrogation of regulome in MLLr leukemia via reporter-based CRISPR/Cas9 screen. Elife. 9. PMID 33001025 DOI: 10.7554/eLife.57858  0.311
2020 Xu B, Mulvey B, Salie M, Yang X, Matsui Y, Nityanandam A, Fan Y, Peng JC. UTX/KDM6A suppresses AP-1 and a gliogenesis program during neural differentiation of human pluripotent stem cells. Epigenetics & Chromatin. 13: 38. PMID 32977832 DOI: 10.1186/s13072-020-00359-3  0.308
2020 Evans MK, Matsui Y, Xu B, Willis C, Loome J, Milburn L, Fan Y, Pagala V, Peng JC. Ybx1 fine-tunes PRC2 activities to control embryonic brain development. Nature Communications. 11: 4060. PMID 32792512 DOI: 10.1038/S41467-020-17878-Y  0.445
2020 Li J, Wang YN, Xu BS, Liu YP, Zhou M, Long T, Li H, Dong H, Nie Y, Chen PR, Wang ED, Liu RJ. Intellectual disability-associated gene ftsj1 is responsible for 2'-O-methylation of specific tRNAs. Embo Reports. e50095. PMID 32558197 DOI: 10.15252/Embr.202050095  0.352
2020 Zeineldin M, Federico S, Chen X, Fan Y, Xu B, Stewart E, Zhou X, Jeon J, Griffiths L, Nguyen R, Norrie J, Easton J, Mulder H, Yergeau D, Liu Y, et al. MYCN amplification and ATRX mutations are incompatible in neuroblastoma. Nature Communications. 11: 913. PMID 32060267 DOI: 10.1038/S41467-020-14682-6  0.328
2020 Wijaya J, Vo BT, Liu J, Xu B, Wu G, Wang Y, Peng J, Zhang J, Janke LJ, Orr BA, Yu J, Roussel MF, Schuetz JD. An ABC transporter drives medulloblastoma pathogenesis by regulating Sonic Hedgehog signaling. Cancer Research. PMID 31948942 DOI: 10.1158/0008-5472.Can-19-2054  0.323
2020 Williams J, Xu B, Putnam D, Chen X. Abstract 6576: DNA methylation reveals alternative promoter usage in genes critical to pediatric tumors Cancer Research. 80: 6576-6576. DOI: 10.1158/1538-7445.Am2020-6576  0.396
2019 Norrie JL, Lupo MS, Xu B, Al Diri I, Valentine M, Putnam D, Griffiths L, Zhang J, Johnson D, Easton J, Shao Y, Honnell V, Frase S, Miller S, Stewart V, et al. Nucleome Dynamics during Retinal Development. Neuron. PMID 31493975 DOI: 10.1016/J.Neuron.2019.08.002  0.382
2019 Tian L, Shao Y, Nance S, Dang J, Xu B, Ma X, Li Y, Ju B, Dong L, Newman S, Zhou X, Schreiner P, Tseng E, Hon T, Ashby M, et al. Long-read sequencing unveils IGH-DUX4 translocation into the silenced IGH allele in B-cell acute lymphoblastic leukemia. Nature Communications. 10: 2789. PMID 31243274 DOI: 10.1038/S41467-019-10637-8  0.344
2019 Hyle J, Zhang Y, Wright S, Xu B, Shao Y, Easton J, Tian L, Feng R, Xu P, Li C. Acute depletion of CTCF directly affects MYC regulation through loss of enhancer-promoter looping. Nucleic Acids Research. PMID 31127282 DOI: 10.1093/Nar/Gkz462  0.472
2019 Silveira AB, Kasper LH, Fan Y, Jin H, Wu G, Shaw TI, Zhu X, Larson JD, Easton J, Shao Y, Yergeau DA, Rosencrance C, Boggs K, Rusch MC, Ding L, ... ... Xu B, et al. H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo. Acta Neuropathologica. PMID 30770999 DOI: 10.1007/S00401-019-01975-4  0.356
2019 Yang X, Xu B, Mulvey B, Evans M, Jordan S, Wang YD, Pagala V, Peng J, Fan Y, Patel A, Peng JC. Differentiation of human pluripotent stem cells into neurons or cortical organoids requires transcriptional co-regulation by UTX and 53BP1. Nature Neuroscience. PMID 30718900 DOI: 10.1038/S41593-018-0328-5  0.42
2018 Larson JD, Kasper LH, Paugh BS, Jin H, Wu G, Kwon CH, Fan Y, Shaw TI, Silveira AB, Qu C, Xu R, Zhu X, Zhang J, Russell HR, Peters JL, ... ... Xu B, et al. Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression. Cancer Cell. PMID 30595505 DOI: 10.1016/J.Ccell.2018.11.015  0.375
2018 Lavado A, Park JY, Paré J, Finkelstein D, Pan H, Xu B, Fan Y, Kumar RP, Neale G, Kwak YD, McKinnon PJ, Johnson RL, Cao X. The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number. Developmental Cell. 47: 576-591.e8. PMID 30523785 DOI: 10.1016/J.Devcel.2018.09.021  0.424
2018 Stewart E, McEvoy J, Wang H, Chen X, Honnell V, Ocarz M, Gordon B, Dapper J, Blankenship K, Yang Y, Li Y, Shaw TI, Cho JH, Wang X, Xu B, et al. Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses. Cancer Cell. PMID 30146332 DOI: 10.1016/J.Ccell.2018.07.012  0.342
2018 Vo BT, Kwon JA, Li C, Finkelstein D, Xu B, Orr BA, Sherr CJ, Roussel MF. Mouse medulloblastoma driven by CRISPR activation of cellular Myc. Scientific Reports. 8: 8733. PMID 29880921 DOI: 10.1038/S41598-018-24956-1  0.372
2018 Wang L, Hiler D, Xu B, AlDiri I, Chen X, Zhou X, Griffiths L, Valentine M, Shirinifard A, Sablauer A, Thiagarajan S, Barabas ME, Zhang J, Johnson D, Frase S, et al. Retinal Cell Type DNA Methylation and Histone Modifications Predict Reprogramming Efficiency and Retinogenesis in 3D Organoid Cultures. Cell Reports. 22: 2601-2614. PMID 29514090 DOI: 10.1016/J.Celrep.2018.01.075  0.325
2018 Zeineldin M, Federico S, Chen X, Xu B, Stewart E, Naranjo A, Hogarty MD, Dyer MA. Abstract IA18: MYCN amplification and ATRX mutations are incompatible in neuroblastoma Cancer Research. 78. DOI: 10.1158/1538-7445.Pedca17-Ia18  0.3
2018 Chang Y, Woessner DW, Lin W, Chen T, Xu B, Fan Y, Tan H, Peng J, Kasper L, Churchman ML, Gerhard DS, Loh ML, Hunger SP, Seth A, Gascoigne K, et al. Abstract IA12: Modeling and targeting CREBBP mutations in relapsed acute lymphoblastic leukemia Cancer Research. 78. DOI: 10.1158/1538-7445.Pedca17-Ia12  0.355
2018 Tian L, Xu B, Shao Y, Ma X, Li Y, Newman S, Zhou X, Ashby M, Hon T, Clark T, Tseng E, Easton J, Zhang J. Abstract 1485: Allelic specificity of immunoglobulin heavy chain (IGH) translocation in B-cell acute lymphoblastic leukemia (B-ALL) unveiled by long-read sequencing Cancer Research. 78: 1485-1485. DOI: 10.1158/1538-7445.Am2018-1485  0.353
2017 Zimmerman MW, Liu Y, He S, Durbin AD, Abraham BJ, Easton J, Shao Y, Xu B, Zhu S, Zhang X, Li Z, Weichert-Leahey N, Young RA, Zhang J, Look AT. c-MYC drives a subset of high-risk pediatric neuroblastomas and is activated through mechanisms including enhancer hijacking and focal enhancer amplification. Cancer Discovery. PMID 29284669 DOI: 10.1158/2159-8290.Cd-17-0993  0.325
2017 Aldiri I, Xu B, Wang L, Chen X, Hiler D, Griffiths L, Valentine M, Shirinifard A, Thiagarajan S, Sablauer A, Barabas ME, Zhang J, Johnson D, Frase S, Zhou X, et al. The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis. Neuron. 94: 550-568.e10. PMID 28472656 DOI: 10.1016/J.Neuron.2017.04.022  0.38
2016 Zhang J, McCastlain K, Yoshihara H, Xu B, Chang Y, Churchman ML, Wu G, Li Y, Wei L, Iacobucci I, Liu Y, Qu C, Wen J, Edmonson M, Payne-Turner D, et al. Deregulation of DUX4 and ERG in acute lymphoblastic leukemia. Nature Genetics. PMID 27776115 DOI: 10.1038/Ng.3691  0.431
2016 Jones BG, Penkert RR, Xu B, Fan Y, Neale G, Gearhart PJ, Hurwitz JL. Binding of estrogen receptors to switch sites and regulatory elements in the immunoglobulin heavy chain locus of activated B cells suggests a direct influence of estrogen on antibody expression. Molecular Immunology. 77: 97-102. PMID 27494228 DOI: 10.1016/J.Molimm.2016.07.015  0.312
2015 Aldiri I, Ajioka I, Xu B, Zhang J, Chen X, Benavente C, Finkelstein D, Johnson D, Akiyama J, Pennacchio LA, Dyer MA. Brg1 coordinates multiple processes during retinogenesis and is a tumor suppressor in retinoblastoma. Development (Cambridge, England). 142: 4092-106. PMID 26628093 DOI: 10.1242/Dev.124800  0.352
2015 Hiler D, Chen X, Hazen J, Kupriyanov S, Carroll PA, Qu C, Xu B, Johnson D, Griffiths L, Frase S, Rodriguez AR, Martin G, Zhang J, Jeon J, Fan Y, et al. Quantification of Retinogenesis in 3D Cultures Reveals Epigenetic Memory and Higher Efficiency in iPSCs Derived from Rod Photoreceptors. Cell Stem Cell. 17: 101-115. PMID 26140606 DOI: 10.1016/J.Stem.2015.05.015  0.316
2015 Li Z, Dai H, Martos SN, Xu B, Gao Y, Li T, Zhu G, Schones DE, Wang Z. Distinct roles of DNMT1-dependent and DNMT1-independent methylation patterns in the genome of mouse embryonic stem cells. Genome Biology. 16: 115. PMID 26032981 DOI: 10.1186/S13059-015-0685-2  0.674
2014 Jose CC, Xu B, Jagannathan L, Trac C, Mallela RK, Hattori T, Lai D, Koide S, Schones DE, Cuddapah S. Epigenetic dysregulation by nickel through repressive chromatin domain disruption. Proceedings of the National Academy of Sciences of the United States of America. 111: 14631-6. PMID 25246589 DOI: 10.1073/Pnas.1406923111  0.689
2013 Xu B, Schones DE, Wang Y, Liang H, Li G. A structural-based strategy for recognition of transcription factor binding sites. Plos One. 8: e52460. PMID 23320072 DOI: 10.1371/Journal.Pone.0052460  0.707
2013 Xu B, Schones DE, Wang Y, Liang H, Li G. Correction: A Structural-Based Strategy for Recognition of Transcription Factor Binding Sites Plos One. 8. DOI: 10.1371/Annotation/0312E1Be-336D-430A-Aa90-101Bbb44F8Db  0.679
2011 Liu RJ, Tan M, Du DH, Xu BS, Eriani G, Wang ED. Peripheral insertion modulates the editing activity of the isolated CP1 domain of leucyl-tRNA synthetase. The Biochemical Journal. 440: 217-27. PMID 21819379 DOI: 10.1042/Bj20111177  0.319
2009 Xu B, Yang Y, Liang H, Zhou Y. An all-atom knowledge-based energy function for protein-DNA threading, docking decoy discrimination, and prediction of transcription-factor binding profiles. Proteins. 76: 718-30. PMID 19274740 DOI: 10.1002/Prot.22384  0.707
2004 Xu B, Huang L, Liang H. Thermodynamic behaviors of polyampholytes at low temperatures. The Journal of Chemical Physics. 121: 7494-500. PMID 15473824 DOI: 10.1063/1.1792191  0.466
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