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David K. Meyerholz - Publications

Affiliations: 
University of Iowa, Iowa City, IA 
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Year Citation  Score
2021 Meyerholz DK, Reznikov LR. Influence of SARS-CoV-2 on airway mucus production: A review and proposed model. Veterinary Pathology. 3009858211058837. PMID 34794359 DOI: 10.1177/03009858211058837  0.656
2021 Bouzek DC, Abou Alaiwa MH, Adam RJ, Pezzulo AA, Reznikov LR, Cook DP, Aguilar Pescozo MI, Ten Eyck P, Wu C, Gross TJ, Hornick DB, Hoffman EA, Meyerholz DK, Stoltz DA. Early Lung Disease Exhibits Bacterial-Dependent and -Independent Abnormalities in Cystic Fibrosis Pigs. American Journal of Respiratory and Critical Care Medicine. PMID 34170795 DOI: 10.1164/rccm.202102-0451OC  0.663
2020 Ortiz ME, Thurman A, Pezzulo AA, Leidinger MR, Klesney-Tait JA, Karp PH, Tan P, Wohlford-Lenane C, McCray PB, Meyerholz DK. Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract. Ebiomedicine. 60: 102976. PMID 32971472 DOI: 10.1016/J.Ebiom.2020.102976  0.306
2020 Sariol A, Mackin S, Allred MG, Ma C, Zhou Y, Zhang Q, Zou X, Abrahante JE, Meyerholz DK, Perlman S. Microglia depletion exacerbates demyelination and impairs remyelination in a neurotropic coronavirus infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 32929007 DOI: 10.1073/Pnas.2007814117  0.316
2020 Rathnayake AD, Zheng J, Kim Y, Perera KD, Mackin S, Meyerholz DK, Kashipathy MM, Battaile KP, Lovell S, Perlman S, Groutas WC, Chang KO. 3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. Science Translational Medicine. PMID 32747425 DOI: 10.1126/Scitranslmed.Abc5332  0.352
2020 Zarei K, Stroik MR, Gansemer ND, Thurman AL, Ostedgaard LS, Ernst SE, Thornell IM, Powers LS, Pezzulo AA, Meyerholz DK, Stoltz DA. Early pathogenesis of cystic fibrosis gallbladder disease in a porcine model. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 32719544 DOI: 10.1038/S41374-020-0474-8  0.377
2020 Sun J, Zhuang Z, Zheng J, Li K, Wong RL, Liu D, Huang J, He J, Zhu A, Zhao J, Li X, Xi Y, Chen R, Alshukairi AN, Chen Z, ... ... Meyerholz DK, et al. Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment. Cell. PMID 32643603 DOI: 10.1016/J.Cell.2020.06.010  0.33
2020 Meyerholz DK, McCray PB. Illuminating COVID-19 lung disease through autopsy studies. Ebiomedicine. 57: 102865. PMID 32629393 DOI: 10.1016/J.Ebiom.2020.102865  0.326
2020 Li K, Li Z, Wohlford-Lenane C, Meyerholz DK, Channappanavar R, An D, Perlman S, McCray PB, He B. Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection. Mbio. 11. PMID 32265331 DOI: 10.1128/Mbio.00554-20  0.331
2020 Meyerholz DK, Beck AP. Histopathologic Evaluation and Scoring of Viral Lung Infection. Methods in Molecular Biology (Clifton, N.J.). 2099: 205-220. PMID 31883098 DOI: 10.1007/978-1-0716-0211-9_16  0.359
2020 Areecheewakul S, Adamcakova-Dodd A, Givens BE, Steines BR, Wang Y, Meyerholz DK, Parizek NJ, Altmaier R, Haque E, O'Shaughnessy PT, Salem AK, Thorne PS. Toxicity assessment of metal oxide nanomaterials using in vitro screening and murine acute inhalation studies Nanoimpact. 18: 100214. DOI: 10.1016/J.Impact.2020.100214  0.303
2019 Schmidt ME, Meyerholz DK, Varga SM. Pre-existing neutralizing antibodies prevent CD8 T cell-mediated immunopathology following respiratory syncytial virus infection. Mucosal Immunology. PMID 31844172 DOI: 10.1038/S41385-019-0243-4  0.311
2019 Krishnamurthy S, Wohlford-Lenane C, Kandimalla S, Sartre G, Meyerholz DK, Théberge V, Hallée S, Duperré AM, Del'Guidice T, Lepetit-Stoffaes JP, Barbeau X, Guay D, McCray PB. Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia. Nature Communications. 10: 4906. PMID 31659165 DOI: 10.1038/S41467-019-12922-Y  0.313
2019 Channappanavar R, Fehr AR, Zheng J, Wohlford-Lenane C, Abrahante JE, Mack M, Sompallae R, McCray PB, Meyerholz DK, Perlman S. IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes. The Journal of Clinical Investigation. 130. PMID 31355779 DOI: 10.1172/Jci126363  0.321
2019 Geesala R, Schanz W, Biggs M, Dixit G, Skurski J, Gurung P, Meyerholz DK, Elliott D, Issuree PD, Maretzky T. Loss of RHBDF2 results in an early-onset spontaneous murine colitis. Journal of Leukocyte Biology. PMID 30694569 DOI: 10.1002/Jlb.4A0718-283Rr  0.331
2018 Meyerholz DK, Beck AP, Goeken JA, Leidinger MR, Ofori-Amanfo GK, Brown HC, Businga TR, Stoltz DA, Reznikov LR, Flaherty HA. Glycogen depletion can increase the specificity of mucin detection in airway tissues. Bmc Research Notes. 11: 763. PMID 30359291 DOI: 10.1186/S13104-018-3855-Y  0.637
2018 Lueschow SR, Stumphy J, Gong H, Kern SL, Elgin TG, Underwood MA, Kalanetra KM, Mills DA, Wong MH, Meyerholz DK, Good M, McElroy SJ. Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes seen in neonatal necrotizing enterocolitis. Plos One. 13: e0204967. PMID 30273395 DOI: 10.1371/Journal.Pone.0204967  0.306
2018 Donovan KM, Leidinger MR, McQuillen LP, Goeken JA, Hogan CM, Harwani SC, Flaherty HA, Meyerholz DK. Allograft Inflammatory Factor 1 as an Immunohistochemical Marker for Macrophages in Multiple Tissues and Laboratory Animal Species. Comparative Medicine. PMID 30227902 DOI: 10.30802/Aalas-Cm-18-000017  0.323
2018 Cooney AL, Singh BK, Loza LM, Thornell IM, Hippee CE, Powers LS, Ostedgaard LS, Meyerholz DK, Wohlford-Lenane C, Stoltz DA, B McCray P, Sinn PL. Widespread airway distribution and short-term phenotypic correction of cystic fibrosis pigs following aerosol delivery of piggyBac/adenovirus. Nucleic Acids Research. PMID 30165523 DOI: 10.1093/Nar/Gky773  0.385
2018 Hua X, Vijay R, Channappanvar R, Athmer J, Meyerholz DK, Pagedar N, Tilley S, Perlman S. Nasal priming by a murine coronavirus provides protective immunity against lethal heterologous virus pneumonia. Jci Insight. 3. PMID 29875310 DOI: 10.1172/Jci.Insight.99025  0.371
2018 Reznikov LR, Meyerholz DK, Abou Alaiwa MH, Kuan SP, Liao YJ, Bormann NL, Bair TB, Price M, Stoltz DA, Welsh MJ. The vagal ganglia transcriptome identifies candidate therapeutics for airway hyperreactivity. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29631359 DOI: 10.1152/Ajplung.00557.2017  0.642
2018 Chu DKW, Hui KPY, Perera RAPM, Miguel E, Niemeyer D, Zhao J, Channappanavar R, Dudas G, Oladipo JO, Traoré A, Fassi-Fihri O, Ali A, Demissié GF, Muth D, Chan MCW, ... ... Meyerholz DK, et al. MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity. Proceedings of the National Academy of Sciences of the United States of America. PMID 29507189 DOI: 10.1073/Pnas.1718769115  0.35
2018 Meyerholz DK, Stoltz DA, Gansemer ND, Ernst SE, Cook DP, Strub MD, LeClair EN, Barker CK, Adam RJ, Leidinger MR, Gibson-Corley KN, Karp PH, Welsh MJ, McCray PB. Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 29467455 DOI: 10.1038/S41374-018-0026-7  0.41
2018 Reznikov LR, Meyerholz DK, Kuan SP, Guevara MV, Atanasova KR, Abou Alaiwa MH. Solitary Cholinergic Stimulation Induces Airway Hyperreactivity and Transcription of Distinct Pro-inflammatory Pathways. Lung. PMID 29380034 DOI: 10.1007/S00408-018-0091-0  0.661
2018 Wheeler DL, Sariol A, Meyerholz DK, Perlman S. Microglia are required for protection against lethal coronavirus encephalitis in mice. The Journal of Clinical Investigation. PMID 29376888 DOI: 10.1172/Jci97229  0.345
2018 Schmidt ME, Knudson CJ, Hartwig SM, Pewe LL, Meyerholz DK, Langlois RA, Harty JT, Varga SM. Memory CD8 T cells mediate severe immunopathology following respiratory syncytial virus infection. Plos Pathogens. 14: e1006810. PMID 29293660 DOI: 10.1371/Journal.Ppat.1006810  0.328
2018 Meyerholz DK, Sieren JC, Beck AP, Flaherty HA. Approaches to Evaluate Lung Inflammation in Translational Research. Veterinary Pathology. 55: 42-52. PMID 28812529 DOI: 10.1177/0300985817726117  0.338
2017 Swatek AM, Lynch TJ, Crooke AK, Anderson PJ, Tyler SR, Brooks L, Ivanovic M, Klesney-Tait JA, Eberlein M, Pena T, Meyerholz DK, Engelhardt JF, Parekh KR. Depletion of Airway Submucosal Glands and TP63+KRT5+ Basal Cells in Obliterative Bronchiolitis. American Journal of Respiratory and Critical Care Medicine. PMID 29236513 DOI: 10.1164/Rccm.201707-1368Oc  0.333
2017 Cook DP, Adam RJ, Zarei K, Deonovic B, Stroik MR, Gansemer ND, Meyerholz DK, Au KF, Stoltz DA. CF airway smooth muscle transcriptome reveals a role for PYK2. Jci Insight. 2. PMID 28878137 DOI: 10.1172/Jci.Insight.95332  0.319
2017 Meyerholz DK, Ofori-Amanfo GK, Leidinger MR, Goeken JA, Khanna R, Sieren JC, Darbro BW, Quelle DE, Weimer JM. Immunohistochemical Markers for Prospective Studies in Neurofibromatosis-1 Porcine Models. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 22155417729357. PMID 28846462 DOI: 10.1369/0022155417729357  0.312
2017 Wheeler DL, Athmer J, Meyerholz DK, Perlman S. Murine Olfactory Bulb Interneurons Survive Infection with a Neurotropic Coronavirus. Journal of Virology. PMID 28835503 DOI: 10.1128/Jvi.01099-17  0.31
2017 Beraldi R, Meyerholz DK, Savinov A, Kovács AD, Weimer JM, Dykstra JA, Geraets RD, Pearce DA. Genetic Ataxia Telangiectasia porcine model phenocopies the multisystemic features of the human disease. Biochimica Et Biophysica Acta. PMID 28746835 DOI: 10.1016/J.Bbadis.2017.07.020  0.369
2017 Adam RJ, Abou Alaiwa MH, Bouzek DC, Cook DP, Gansemer ND, Taft PJ, Powers LS, Stroik MR, Hoegger MJ, McMenimen JD, Hoffman EA, Zabner J, Welsh MJ, Meyerholz DK, Stoltz DA. Postnatal Airway Growth in Cystic Fibrosis Piglets. Journal of Applied Physiology (Bethesda, Md. : 1985). jap.00263.2017. PMID 28620056 DOI: 10.1152/Japplphysiol.00263.2017  0.393
2017 Ostedgaard LS, Moninger TO, McMenimen JD, Sawin NM, Parker CP, Thornell IM, Powers LS, Gansemer ND, Bouzek DC, Cook DP, Meyerholz DK, Abou Alaiwa MH, Stoltz DA, Welsh MJ. Gel-forming mucins form distinct morphologic structures in airways. Proceedings of the National Academy of Sciences of the United States of America. PMID 28607090 DOI: 10.1073/Pnas.1703228114  0.388
2017 Meyerholz DK, Reznikov LR. Simple and reproducible approaches for the collection of select porcine ganglia. Journal of Neuroscience Methods. PMID 28602889 DOI: 10.1016/J.Jneumeth.2017.06.005  0.629
2017 Channappanavar R, Fett C, Mack M, Ten Eyck PP, Meyerholz DK, Perlman S. Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 28373583 DOI: 10.4049/Jimmunol.1601896  0.345
2017 Li K, Wohlford-Lenane CL, Channappanavar R, Park JE, Earnest JT, Bair TB, Bates AM, Brogden KA, Flaherty HA, Gallagher T, Meyerholz DK, Perlman S, McCray PB. Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 28348219 DOI: 10.1073/Pnas.1619109114  0.405
2017 Cook DP, Adam RJ, Abou Alaiwa MH, Eberlein M, Klesney-Tait JA, Parekh KR, Meyerholz DK, Stoltz DA. Mounier-Kuhn syndrome: a case of tracheal smooth muscle remodeling. Clinical Case Reports. 5: 93-96. PMID 28174630 DOI: 10.1002/Ccr3.794  0.324
2016 Fehr AR, Channappanavar R, Jankevicius G, Fett C, Zhao J, Athmer J, Meyerholz DK, Ahel I, Perlman S. The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection. Mbio. 7. PMID 27965448 DOI: 10.1128/Mbio.01721-16  0.347
2016 Reznikov LR, Meyerholz DK, Adam RJ, Abou Alaiwa M, Jaffer O, Michalski AS, Powers LS, Price MP, Stoltz DA, Welsh MJ. Acid-Sensing Ion Channel 1a Contributes to Airway Hyperreactivity in Mice. Plos One. 11: e0166089. PMID 27820848 DOI: 10.1371/Journal.Pone.0166089  0.634
2016 Cooney AL, Abou Alaiwa MH, Shah VS, Bouzek DC, Stroik MR, Powers LS, Gansemer ND, Meyerholz DK, Welsh MJ, Stoltz DA, Sinn PL, McCray PB. Lentiviral-mediated phenotypic correction of cystic fibrosis pigs. Jci Insight. 1. PMID 27656681 DOI: 10.1172/Jci.Insight.88730  0.396
2016 Zhao J, Zhao J, Mangalam AK, Channappanavar R, Fett C, Meyerholz DK, Agnihothram S, Baric RS, David CS, Perlman S. Airway Memory CD4(+) T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses. Immunity. PMID 27287409 DOI: 10.1016/J.Immuni.2016.05.006  0.342
2016 Meyerholz DK. Lessons learned from the cystic fibrosis pig. Theriogenology. 86: 427-32. PMID 27142487 DOI: 10.1016/J.Theriogenology.2016.04.057  0.413
2016 Bartlett JA, Ramachandran S, Wohlford-Lenane CL, Barker CK, Pezzulo AA, Zabner J, Welsh MJ, Meyerholz DK, Stoltz DA, McCray PB. Newborn Cystic Fibrosis Pigs Have a Blunted Early Response to an Inflammatory Stimulus. American Journal of Respiratory and Critical Care Medicine. PMID 27027566 DOI: 10.1164/Rccm.201510-2112Oc  0.387
2016 Meyerholz DK. Modeling Emergent Diseases: Lessons From Middle East Respiratory Syndrome Veterinary Pathology. 53: 517-518. PMID 27000399 DOI: 10.1177/0300985816634811  0.406
2016 Channappanavar R, Fehr AR, Vijay R, Mack M, Zhao J, Meyerholz DK, Perlman S. Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice. Cell Host & Microbe. 19: 181-93. PMID 26867177 DOI: 10.1016/J.Chom.2016.01.007  0.384
2016 Shah VS, Meyerholz DK, Tang XX, Reznikov L, Abou Alaiwa M, Ernst SE, Karp PH, Wohlford-Lenane CL, Heilmann KP, Leidinger MR, Allen PD, Zabner J, McCray PB, Ostedgaard LS, Stoltz DA, et al. Airway acidification initiates host defense abnormalities in cystic fibrosis mice. Science (New York, N.Y.). 351: 503-7. PMID 26823428 DOI: 10.1126/Science.Aad5589  0.687
2016 Li X, Tang XX, Vargas Buonfiglio LG, Comellas AP, Thornell IM, Ramachandran S, Karp PH, Taft PJ, Sheets K, Abou Alaiwa MH, Welsh MJ, Meyerholz DK, Stoltz DA, Zabner J. Electrolyte transport properties in distal small airways from cystic fibrosis pigs with implications for host defense. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00422.2015. PMID 26801568 DOI: 10.1152/Ajplung.00422.2015  0.395
2015 Meyerholz DK, Lambertz AM, McCray PB. Dipeptidyl Peptidase 4 Distribution in the Human Respiratory Tract: Implications for the Middle East Respiratory Syndrome. The American Journal of Pathology. PMID 26597880 DOI: 10.1016/J.Ajpath.2015.09.014  0.39
2015 Meyerholz DK, Lambertz AM, Reznikov LR, Ofori-Amanfo GK, Karp PH, McCray PB, Welsh MJ, Stoltz DA. Immunohistochemical Detection of Markers for Translational Studies of Lung Disease in Pigs and Humans. Toxicologic Pathology. PMID 26511846 DOI: 10.1177/0192623315609691  0.672
2015 Cook DP, Rector MV, Bouzek DC, Michalski AS, Gansemer ND, Reznikov LR, Li X, Stroik MR, Ostedgaard LS, Abou Alaiwa MH, Thompson MA, Prakash YS, Krishnan R, Meyerholz DK, Seow CY, et al. CFTR in Sarcoplasmic Reticulum of Airway Smooth Muscle: Implications for Airway Contractility. American Journal of Respiratory and Critical Care Medicine. PMID 26488271 DOI: 10.1164/Rccm.201508-1562Oc  0.677
2015 Li K, Wohlford-Lenane C, Perlman S, Zhao J, Jewell AK, Reznikov LR, Gibson-Corley KN, Meyerholz DK, McCray PB. Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4. The Journal of Infectious Diseases. PMID 26486634 DOI: 10.1093/Infdis/Jiv499  0.693
2015 Vijay R, Hua X, Meyerholz DK, Miki Y, Yamamoto K, Gelb M, Murakami M, Perlman S. Critical role of phospholipase A2 group IID in age-related susceptibility to severe acute respiratory syndrome-CoV infection. The Journal of Experimental Medicine. PMID 26392224 DOI: 10.1084/Jem.20150632  0.388
2015 Beraldi R, Chan CH, Rogers CS, Kovács AD, Meyerholz DK, Trantzas C, Lambertz AM, Darbro BW, Weber KL, White KA, Rheeden RV, Kruer MC, Dacken BA, Wang XJ, Davis BT, et al. A novel porcine model of ataxia telangiectasia reproduces neurological features and motor deficits of human disease. Human Molecular Genetics. PMID 26374845 DOI: 10.1093/Hmg/Ddv356  0.335
2015 Gibson-Corley KN, Meyerholz DK, Engelhardt JF. Pancreatic pathophysiology in cystic fibrosis. The Journal of Pathology. PMID 26365583 DOI: 10.1002/Path.4634  0.374
2015 Channappanavar R, Lu L, Xia S, Du L, Meyerholz DK, Perlman S, Jiang S. Protective Effect of Intranasal Regimens Containing Peptidic Middle East Respiratory Syndrome Coronavirus Fusion Inhibitor Against MERS-CoV Infection. The Journal of Infectious Diseases. PMID 26164863 DOI: 10.1093/Infdis/Jiv325  0.303
2015 Diwakar A, Adam RJ, Michalski AS, Tamegnon MM, Fischer AJ, Launspach JL, Horan RA, Kao SC, Chaloner K, Meyerholz DK, Stoltz DA. Sonographic evidence of abnormal tracheal cartilage ring structure in cystic fibrosis. The Laryngoscope. PMID 25827636 DOI: 10.1002/Lary.25255  0.322
2015 Zhao J, Perera RA, Kayali G, Meyerholz D, Perlman S, Peiris M. Passive immunotherapy with dromedary immune serum in an experimental animal model for Middle East respiratory syndrome coronavirus infection. Journal of Virology. 89: 6117-20. PMID 25787284 DOI: 10.1128/Jvi.00446-15  0.34
2015 Knudson CJ, Hartwig SM, Meyerholz DK, Varga SM. RSV vaccine-enhanced disease is orchestrated by the combined actions of distinct CD4 T cell subsets. Plos Pathogens. 11: e1004757. PMID 25769044 DOI: 10.1371/Journal.Ppat.1004757  0.334
2015 Bartlett JA, Meyerholz DK, Wohlford-Lenane CL, Naumann PW, Salzman NH, McCray PB. Increased susceptibility to otitis media in a Splunc1-deficient mouse model. Disease Models & Mechanisms. 8: 501-8. PMID 25765466 DOI: 10.1242/Dmm.019646  0.376
2015 Stoltz DA, Meyerholz DK, Welsh MJ. Origins of cystic fibrosis lung disease. The New England Journal of Medicine. 372: 351-62. PMID 25607428 DOI: 10.1056/Nejmra1300109  0.365
2015 Olivier AK, Gibson-Corley KN, Meyerholz DK. Animal models of gastrointestinal and liver diseases. Animal models of cystic fibrosis: gastrointestinal, pancreatic, and hepatobiliary disease and pathophysiology. American Journal of Physiology. Gastrointestinal and Liver Physiology. 308: G459-71. PMID 25591863 DOI: 10.1152/Ajpgi.00146.2014  0.361
2015 Fehr AR, Athmer J, Channappanavar R, Phillips JM, Meyerholz DK, Perlman S. The nsp3 macrodomain promotes virulence in mice with coronavirus-induced encephalitis. Journal of Virology. 89: 1523-36. PMID 25428866 DOI: 10.1128/Jvi.02596-14  0.348
2015 Uc A, Olivier AK, Griffin MA, Meyerholz DK, Yao J, Abu-El-Haija M, Buchanan KM, Vanegas Calderón OG, Abu-El-Haija M, Pezzulo AA, Reznikov LR, Hoegger MJ, Rector MV, Ostedgaard LS, Taft PJ, et al. Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass. Clinical Science (London, England : 1979). 128: 131-42. PMID 25142104 DOI: 10.1042/Cs20140059  0.647
2015 Guimaraes-Young A, Neff T, Meyerholz DK, Dupuy AJ, Goodheart MJ. Abstract 4192: Identification of novel genetic drivers of vulvar carcinoma in a Sleeping Beauty model of spontaneous cancer Cancer Research. 75: 4192-4192. DOI: 10.1158/1538-7445.Am2015-4192  0.312
2014 Reed SM, Hagen J, Muniz VP, Rosean TR, Borcherding N, Sciegienka S, Goeken JA, Naumann PW, Zhang W, Tompkins VS, Janz S, Meyerholz DK, Quelle DE. NIAM-deficient mice are predisposed to the development of proliferative lesions including B-cell lymphomas. Plos One. 9: e112126. PMID 25393878 DOI: 10.1371/Journal.Pone.0112126  0.316
2014 Channappanavar R, Fett C, Zhao J, Meyerholz DK, Perlman S. Virus-specific memory CD8 T cells provide substantial protection from lethal severe acute respiratory syndrome coronavirus infection. Journal of Virology. 88: 11034-44. PMID 25056892 DOI: 10.1128/Jvi.01505-14  0.309
2014 Sun X, Olivier AK, Yi Y, Pope CE, Hayden HS, Liang B, Sui H, Zhou W, Hager KR, Zhang Y, Liu X, Yan Z, Fisher JT, Keiser NW, Song Y, ... ... Meyerholz DK, et al. Gastrointestinal pathology in juvenile and adult CFTR-knockout ferrets. The American Journal of Pathology. 184: 1309-22. PMID 24637292 DOI: 10.1016/J.Ajpath.2014.01.035  0.361
2014 Rasmussen JA, Post DM, Gibson BW, Lindemann SR, Apicella MA, Meyerholz DK, Jones BD. Francisella tularensis Schu S4 lipopolysaccharide core sugar and O-antigen mutants are attenuated in a mouse model of tularemia. Infection and Immunity. 82: 1523-39. PMID 24452684 DOI: 10.1128/Iai.01640-13  0.315
2014 Sun X, Olivier AK, Liang B, Yi Y, Sui H, Evans TI, Zhang Y, Zhou W, Tyler SR, Fisher JT, Keiser NW, Liu X, Yan Z, Song Y, Goeken JA, ... ... Meyerholz DK, et al. Lung phenotype of juvenile and adult cystic fibrosis transmembrane conductance regulator-knockout ferrets. American Journal of Respiratory Cell and Molecular Biology. 50: 502-12. PMID 24074402 DOI: 10.1165/Rcmb.2013-0261Oc  0.389
2013 Hochstedler CM, Leidinger MR, Maher-Sturm MT, Gibson-Corley KN, Meyerholz DK. Immunohistochemical detection of arginase-I expression in formalin-fixed lung and other tissues Journal of Histotechnology. 36: 128-134. PMID 25332513 DOI: 10.1179/2046023613Y.0000000032  0.373
2013 Adam RJ, Michalski AS, Bauer C, Abou Alaiwa MH, Gross TJ, Awadalla MS, Bouzek DC, Gansemer ND, Taft PJ, Hoegger MJ, Diwakar A, Ochs M, Reinhardt JM, Hoffman EA, Beichel RR, ... Meyerholz DK, et al. Air trapping and airflow obstruction in newborn cystic fibrosis piglets. American Journal of Respiratory and Critical Care Medicine. 188: 1434-41. PMID 24168209 DOI: 10.1164/Rccm.201307-1268Oc  0.339
2013 Sanders PN, Koval OM, Jaffer OA, Prasad AM, Businga TR, Scott JA, Hayden PJ, Luczak ED, Dickey DD, Allamargot C, Olivier AK, Meyerholz DK, Robison AJ, Winder DG, Blackwell TS, et al. CaMKII is essential for the proasthmatic effects of oxidation. Science Translational Medicine. 5: 195ra97. PMID 23884469 DOI: 10.1126/Scitranslmed.3006135  0.331
2013 Stoltz DA, Rokhlina T, Ernst SE, Pezzulo AA, Ostedgaard LS, Karp PH, Samuel MS, Reznikov LR, Rector MV, Gansemer ND, Bouzek DC, Alaiwa MH, Hoegger MJ, Ludwig PS, Taft PJ, ... ... Meyerholz DK, et al. Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs. The Journal of Clinical Investigation. 123: 2685-93. PMID 23676501 DOI: 10.1172/Jci68867  0.677
2013 Klesney-Tait J, Keck K, Li X, Gilfillan S, Otero K, Baruah S, Meyerholz DK, Varga SM, Knudson CJ, Moninger TO, Moreland J, Zabner J, Colonna M. Transepithelial migration of neutrophils into the lung requires TREM-1. The Journal of Clinical Investigation. 123: 138-49. PMID 23241959 DOI: 10.1172/Jci64181  0.385
2013 Sui H, Olivier AK, Klesney-Tait JA, Brooks L, Tyler SR, Sun X, Skopec A, Kline J, Sanchez PG, Meyerholz DK, Zavazava N, Iannettoni M, Engelhardt JF, Parekh KR. Ferret lung transplant: an orthotopic model of obliterative bronchiolitis. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 13: 467-73. PMID 23205765 DOI: 10.1111/J.1600-6143.2012.04337.X  0.304
2012 Uc A, Giriyappa R, Meyerholz DK, Griffin M, Ostedgaard LS, Tang XX, Abu-El-Haija M, Stoltz DA, Ludwig P, Pezzulo A, Abu-El-Haija M, Taft P, Welsh MJ. Pancreatic and biliary secretion are both altered in cystic fibrosis pigs. American Journal of Physiology. Gastrointestinal and Liver Physiology. 303: G961-8. PMID 22936270 DOI: 10.1152/Ajpgi.00030.2012  0.317
2012 Chang EH, Pezzulo AA, Meyerholz DK, Potash AE, Wallen TJ, Reznikov LR, Sieren JC, Karp PH, Ernst S, Moninger TO, Gansemer ND, McCray PB, Stoltz DA, Welsh MJ, Zabner J. Sinus hypoplasia precedes sinus infection in a porcine model of cystic fibrosis. The Laryngoscope. 122: 1898-905. PMID 22711071 DOI: 10.1002/Lary.23392  0.685
2012 Abu-El-Haija M, Ramachandran S, Meyerholz DK, Abu-El-Haija M, Griffin M, Giriyappa RL, Stoltz DA, Welsh MJ, McCray PB, Uc A. Pancreatic damage in fetal and newborn cystic fibrosis pigs involves the activation of inflammatory and remodeling pathways. The American Journal of Pathology. 181: 499-507. PMID 22683312 DOI: 10.1016/J.Ajpath.2012.04.024  0.373
2012 Curtiss ML, Gorman JV, Businga TR, Traver G, Singh M, Meyerholz DK, Kline JN, Murphy AJ, Valenzuela DM, Colgan JD, Rothman PB, Cassel SL. Tim-1 regulates Th2 responses in an airway hypersensitivity model. European Journal of Immunology. 42: 651-61. PMID 22144095 DOI: 10.1002/Eji.201141581  0.343
2012 Kulhankova K, Fan K, Tygrett L, Young B, Coleman R, Meyerholz D, Schlueter A, Waldschmidt T, Cook R, Legge K. Fetal/neonatal exposure to ethanol alters pulmonary immunity and increases the severity of respiratory infections Alcohol. 46: 176. DOI: 10.1016/J.Alcohol.2011.09.012  0.307
2011 Abu-El-Haija M, Sinkora M, Meyerholz DK, Welsh MJ, McCray PB, Butler J, Uc A. An activated immune and inflammatory response targets the pancreas of newborn pigs with cystic fibrosis. Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.]. 11: 506-15. PMID 22057257 DOI: 10.1159/000332582  0.345
2011 Weiss KA, Christiaansen AF, Fulton RB, Meyerholz DK, Varga SM. Multiple CD4+ T cell subsets produce immunomodulatory IL-10 during respiratory syncytial virus infection. Journal of Immunology (Baltimore, Md. : 1950). 187: 3145-54. PMID 21844390 DOI: 10.4049/Jimmunol.1100764  0.321
2011 Muniz VP, Barnes JM, Paliwal S, Zhang X, Tang X, Chen S, Zamba KD, Cullen JJ, Meyerholz DK, Meyers S, Davis JN, Grossman SR, Henry MD, Quelle DE. The ARF tumor suppressor inhibits tumor cell colonization independent of p53 in a novel mouse model of pancreatic ductal adenocarcinoma metastasis. Molecular Cancer Research : McR. 9: 867-77. PMID 21636682 DOI: 10.1158/1541-7786.Mcr-10-0475  0.311
2011 Ostedgaard LS, Meyerholz DK, Chen JH, Pezzulo AA, Karp PH, Rokhlina T, Ernst SE, Hanfland RA, Reznikov LR, Ludwig PS, Rogan MP, Davis GJ, Dohrn CL, Wohlford-Lenane C, Taft PJ, et al. The ΔF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs. Science Translational Medicine. 3: 74ra24. PMID 21411740 DOI: 10.1126/Scitranslmed.3001868  0.644
2011 Ostedgaard LS, Meyerholz DK, Vermeer DW, Karp PH, Schneider L, Sigmund CD, Welsh MJ. Cystic fibrosis transmembrane conductance regulator with a shortened R domain rescues the intestinal phenotype of CFTR-/- mice. Proceedings of the National Academy of Sciences of the United States of America. 108: 2921-6. PMID 21285372 DOI: 10.1073/Pnas.1019752108  0.305
2011 Uc A, Stoltz DA, Ludwig P, Pezzulo A, Griffin M, Abu-El-Haija M, Abu-El-Haija M, Meyerholz DK, Taft P, Welsh MJ. 271* Pancreatic and biliary secretion differ in cystic fibrosis and wild-type pigs Journal of Cystic Fibrosis. 10. DOI: 10.1016/S1569-1993(11)60285-3  0.3
2011 Uc A, Stoltz DA, Ludwig PS, Pezzulo A, Griffin M, Abu-El-Haija M, Abu-El-Haija M, Meyerholz D, Taft PJ, Welsh MJ. Pancreatic and Biliary Secretion Differ in Cystic Fibrosis and Wild-Type Pigs Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)63553-1  0.317
2010 Peters AL, Stunz LL, Meyerholz DK, Mohan C, Bishop GA. Latent membrane protein 1, the EBV-encoded oncogenic mimic of CD40, accelerates autoimmunity in B6.Sle1 mice. Journal of Immunology (Baltimore, Md. : 1950). 185: 4053-62. PMID 20810985 DOI: 10.4049/Jimmunol.0904065  0.313
2010 Sun X, Sui H, Fisher JT, Yan Z, Liu X, Cho HJ, Joo NS, Zhang Y, Zhou W, Yi Y, Kinyon JM, Lei-Butters DC, Griffin MA, Naumann P, Luo M, ... ... Meyerholz DK, et al. Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis. The Journal of Clinical Investigation. 120: 3149-60. PMID 20739752 DOI: 10.1172/Jci43052  0.42
2010 Ulland TK, Buchan BW, Ketterer MR, Fernandes-Alnemri T, Meyerholz DK, Apicella MA, Alnemri ES, Jones BD, Nauseef WM, Sutterwala FS. Cutting edge: mutation of Francisella tularensis mviN leads to increased macrophage absent in melanoma 2 inflammasome activation and a loss of virulence. Journal of Immunology (Baltimore, Md. : 1950). 185: 2670-4. PMID 20679532 DOI: 10.4049/Jimmunol.1001610  0.315
2010 Fulton RB, Meyerholz DK, Varga SM. Foxp3+ CD4 regulatory T cells limit pulmonary immunopathology by modulating the CD8 T cell response during respiratory syncytial virus infection. Journal of Immunology (Baltimore, Md. : 1950). 185: 2382-92. PMID 20639494 DOI: 10.4049/Jimmunol.1000423  0.351
2010 Meyerholz DK, Stoltz DA, Namati E, Ramachandran S, Pezzulo AA, Smith AR, Rector MV, Suter MJ, Kao S, McLennan G, Tearney GJ, Zabner J, McCray PB, Welsh MJ. Loss of cystic fibrosis transmembrane conductance regulator function produces abnormalities in tracheal development in neonatal pigs and young children. American Journal of Respiratory and Critical Care Medicine. 182: 1251-61. PMID 20622026 DOI: 10.1164/Rccm.201004-0643Oc  0.368
2010 Langlois RA, Meyerholz DK, Coleman RA, Cook RT, Waldschmidt TJ, Legge KL. Oseltamivir treatment prevents the increased influenza virus disease severity and lethality occurring in chronic ethanol consuming mice. Alcoholism, Clinical and Experimental Research. 34: 1425-31. PMID 20497135 DOI: 10.1111/J.1530-0277.2010.01226.X  0.345
2010 Stoltz DA, Meyerholz DK, Pezzulo AA, Ramachandran S, Rogan MP, Davis GJ, Hanfland RA, Wohlford-Lenane C, Dohrn CL, Bartlett JA, Nelson GA, Chang EH, Taft PJ, Ludwig PS, Estin M, et al. Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth. Science Translational Medicine. 2: 29ra31. PMID 20427821 DOI: 10.1126/Scitranslmed.3000928  0.414
2010 Radi ZA, Meyerholz DK, Ackermann MR. Pulmonary cyclooxygenase-1 (COX-1) and COX-2 cellular expression and distribution after respiratory syncytial virus and parainfluenza virus infection. Viral Immunology. 23: 43-8. PMID 20121401 DOI: 10.1089/Vim.2009.0042  0.374
2010 Meyerholz DK, Stoltz DA, Pezzulo AA, Welsh MJ. Pathology of gastrointestinal organs in a porcine model of cystic fibrosis. The American Journal of Pathology. 176: 1377-89. PMID 20110417 DOI: 10.2353/Ajpath.2010.090849  0.411
2010 O'Keefe BR, Giomarelli B, Barnard DL, Shenoy SR, Chan PK, McMahon JB, Palmer KE, Barnett BW, Meyerholz DK, Wohlford-Lenane CL, McCray PB. Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae. Journal of Virology. 84: 2511-21. PMID 20032190 DOI: 10.1128/Jvi.02322-09  0.331
2010 Berquam-Vrieze KE, Nannapaneni K, Zagorodna O, Mullighan C, Meyerholz DK, Copeland N, Jenkins N, Knudson CM, Scheetz T, Dupuy AJ. Abstract 1188: Cell-of-origin determines genetic selection and defines T-cell acute lymphocytic leukemia sub-types in mouse models Cancer Research. 70: 1188-1188. DOI: 10.1158/1538-7445.Am10-1188  0.302
2010 Sun X, Sui H, Liu X, Fisher J, Yan Z, Yi Y, Luo M, Zhang Y, Zhou W, Meyerholz DK, Engelhardt JF. Tissue-Specific Complementation of Intestinal Disease in a Transgenic CFTR-Knockout Ferret Model Generated by SCNT. Biology of Reproduction. 83: 401-401. DOI: 10.1093/Biolreprod/83.S1.401  0.331
2009 Wohlford-Lenane CL, Meyerholz DK, Perlman S, Zhou H, Tran D, Selsted ME, McCray PB. Rhesus theta-defensin prevents death in a mouse model of severe acute respiratory syndrome coronavirus pulmonary disease. Journal of Virology. 83: 11385-90. PMID 19710146 DOI: 10.1128/Jvi.01363-09  0.398
2009 Murthy S, Adamcakova-Dodd A, Perry SS, Tephly LA, Keller RM, Metwali N, Meyerholz DK, Wang Y, Glogauer M, Thorne PS, Carter AB. Modulation of reactive oxygen species by Rac1 or catalase prevents asbestos-induced pulmonary fibrosis American Journal of Physiology - Lung Cellular and Molecular Physiology. 297. PMID 19684199 DOI: 10.1152/Ajplung.90590.2008  0.345
2009 Khanolkar A, Hartwig SM, Haag BA, Meyerholz DK, Epping LL, Haring JS, Varga SM, Harty JT. Protective and pathologic roles of the immune response to mouse hepatitis virus type 1: implications for severe acute respiratory syndrome. Journal of Virology. 83: 9258-72. PMID 19570864 DOI: 10.1128/Jvi.00355-09  0.373
2009 Khanolkar A, Hartwig SM, Haag BA, Meyerholz DK, Harty JT, Varga SM. Toll-like receptor 4 deficiency increases disease and mortality after mouse hepatitis virus type 1 infection of susceptible C3H mice. Journal of Virology. 83: 8946-56. PMID 19553337 DOI: 10.1128/Jvi.01857-08  0.351
2009 McGill J, Meyerholz DK, Edsen-Moore M, Young B, Coleman RA, Schlueter AJ, Waldschmidt TJ, Cook RT, Legge KL. Fetal exposure to ethanol has long-term effects on the severity of influenza virus infections. Journal of Immunology (Baltimore, Md. : 1950). 182: 7803-8. PMID 19494304 DOI: 10.4049/Jimmunol.0803881  0.333
2009 Meyerholz DK, Rodgers J, Castilow EM, Varga SM. Alcian Blue and Pyronine Y histochemical stains permit assessment of multiple parameters in pulmonary disease models. Veterinary Pathology. 46: 325-8. PMID 19261646 DOI: 10.1354/Vp.46-2-325  0.339
2009 Sow FB, Gallup JM, Meyerholz DK, Ackermann MR. Gene profiling studies in the neonatal ovine lung show enhancing effects of VEGF on the immune response. Developmental and Comparative Immunology. 33: 761-71. PMID 19189846 DOI: 10.1016/J.Dci.2009.01.004  0.357
2009 Case AJ, Mcgill JL, Sangster SC, Madsen JM, Tygrett LT, Johns AG, Takahashi T, Shirasawa T, Spitz DR, Meyerholz DK, Waldschmidt TJ, Legge KL, Domann FE. Heightened Susceptibility to Influenza Mortality in Immunodeficient Mice Caused by a T-Cell Specific Defect in SOD2. Blood. 114: 1655-1655. DOI: 10.1182/Blood.V114.22.1655.1655  0.311
2008 Rogers CS, Stoltz DA, Meyerholz DK, Ostedgaard LS, Rokhlina T, Taft PJ, Rogan MP, Pezzulo AA, Karp PH, Itani OA, Kabel AC, Wohlford-Lenane CL, Davis GJ, Hanfland RA, Smith TL, et al. Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs. Science (New York, N.Y.). 321: 1837-41. PMID 18818360 DOI: 10.1126/Science.1163600  0.401
2008 Meyerholz DK, Williard DE, Grittmann A, Samuel I. Murine pancreatic duct ligation induces stress kinase activation, acute pancreatitis, and acute lung injury. American Journal of Surgery. 196: 675-682. PMID 18789417 DOI: 10.1016/J.Amjsurg.2008.07.009  0.301
2008 Meyerholz DK, Edsen-Moore M, McGill J, Coleman RA, Cook RT, Legge KL. Chronic alcohol consumption increases the severity of murine influenza virus infections. Journal of Immunology (Baltimore, Md. : 1950). 181: 641-8. PMID 18566431 DOI: 10.4049/Jimmunol.181.1.641  0.309
2008 Netland J, Meyerholz DK, Moore S, Cassell M, Perlman S. Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2. Journal of Virology. 82: 7264-75. PMID 18495771 DOI: 10.1128/Jvi.00737-08  0.339
2008 Rogers CS, Abraham WM, Brogden KA, Engelhardt JF, Fisher JT, McCray PB, McLennan G, Meyerholz DK, Namati E, Ostedgaard LS, Prather RS, Sabater JR, Stoltz DA, Zabner J, Welsh MJ. The porcine lung as a potential model for cystic fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 295: L240-63. PMID 18487356 DOI: 10.1152/Ajplung.90203.2008  0.417
2008 Castilow EM, Meyerholz DK, Varga SM. IL-13 is required for eosinophil entry into the lung during respiratory syncytial virus vaccine-enhanced disease. Journal of Immunology (Baltimore, Md. : 1950). 180: 2376-84. PMID 18250447 DOI: 10.4049/Jimmunol.180.4.2376  0.349
2008 Castilow EM, Olson MR, Meyerholz DK, Varga SM. Differential role of gamma interferon in inhibiting pulmonary eosinophilia and exacerbating systemic disease in fusion protein-immunized mice undergoing challenge infection with respiratory syncytial virus. Journal of Virology. 82: 2196-207. PMID 18094193 DOI: 10.1128/Jvi.01949-07  0.339
2007 Meyerholz DK, Gallup JM, Lazic T, de Macedo MM, Lehmkuhl HD, Ackermann MR. Pretreatment with recombinant human vascular endothelial growth factor reduces virus replication and inflammation in a perinatal lamb model of respiratory syncytial virus infection. Viral Immunology. 20: 188-96. PMID 17425433 DOI: 10.1089/Vim.2006.0089  0.356
2007 Fach SJ, Meyerholz DK, Gallup JM, Ackermann MR, Lehmkuhl HD, Sacco RE. Neonatal ovine pulmonary dendritic cells support bovine respiratory syncytial virus replication with enhanced interleukin (IL)-4 And IL-10 gene transcripts. Viral Immunology. 20: 119-30. PMID 17425426 DOI: 10.1089/Vim.2006.0056  0.357
2007 McCray PB, Pewe L, Wohlford-Lenane C, Hickey M, Manzel L, Shi L, Netland J, Jia HP, Halabi C, Sigmund CD, Meyerholz DK, Kirby P, Look DC, Perlman S. Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus. Journal of Virology. 81: 813-21. PMID 17079315 DOI: 10.1128/Jvi.02012-06  0.388
2006 Meyerholz DK, Grubor B, Lazic T, Gallup JM, de Macedo MM, McCray PB, Ackermann MR. Monocytic/macrophagic pneumonitis after intrabronchial deposition of vascular endothelial growth factor in neonatal lambs. Veterinary Pathology. 43: 689-94. PMID 16966446 DOI: 10.1354/Vp.43-5-689  0.321
2006 Grubor B, Meyerholz DK, Ackermann MR. Collectins and cationic antimicrobial peptides of the respiratory epithelia. Veterinary Pathology. 43: 595-612. PMID 16966437 DOI: 10.1354/Vp.43-5-595  0.337
2006 Meyerholz DK, DeGraaff JA, Gallup JM, Olivier AK, Ackermann MR. Depletion of alveolar glycogen corresponds with immunohistochemical development of CD208 antigen expression in perinatal lamb lung. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 54: 1247-53. PMID 16899762 DOI: 10.1369/Jhc.6A7002.2006  0.315
2006 Kawashima K, Meyerholz DK, Gallup JM, Grubor B, Lazic T, Lehmkuhl HD, Ackermann MR. Differential expression of ovine innate immune genes by preterm and neonatal lung epithelia infected with respiratory syncytial virus. Viral Immunology. 19: 316-23. PMID 16817774 DOI: 10.1089/Vim.2006.19.316  0.348
2006 Meyerholz DK, Kawashima K, Gallup JM, Grubor B, Ackermann MR. Expression of select immune genes (surfactant proteins A and D, sheep beta defensin 1, and toll-like receptor 4) by respiratory epithelia is developmentally regulated in the preterm neonatal lamb. Developmental and Comparative Immunology. 30: 1060-9. PMID 16510184 DOI: 10.1016/J.Dci.2006.01.001  0.329
2005 Meyerholz DK, Ackermann MR. Antimicrobial peptides and surfactant proteins in ruminant respiratory tract disease. Veterinary Immunology and Immunopathology. 108: 91-6. PMID 16140392 DOI: 10.1016/J.Vetimm.2005.08.003  0.332
2005 Meyerholz DK, Vanloubbeeck YE, Hostetter SJ, Jordan DM, Fales-Williams AJ. Surveillance of amyloidosis and other diseases at necropsy in captive trumpeter swans (Cygnus buccinator). Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 17: 295-8. PMID 15945393 DOI: 10.1177/104063870501700318  0.309
2005 Meyerholz DK, Haynes JS. Actinobacillus capsulatus septicemia in a domestic rabbit (Oryctolagus cuniculus). Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 17: 83-5. PMID 15690960 DOI: 10.1177/104063870501700119  0.32
2004 Meyerholz DK, Grubor B, Fach SJ, Sacco RE, Lehmkuhl HD, Gallup JM, Ackermann MR. Reduced clearance of respiratory syncytial virus infection in a preterm lamb model. Microbes and Infection / Institut Pasteur. 6: 1312-9. PMID 15555538 DOI: 10.1016/J.Micinf.2004.08.006  0.338
2004 Meyerholz DK, Grubor B, Gallup JM, Lehmkuhl HD, Anderson RD, Lazic T, Ackermann MR. Adenovirus-mediated gene therapy enhances parainfluenza virus 3 infection in neonatal lambs. Journal of Clinical Microbiology. 42: 4780-7. PMID 15472341 DOI: 10.1128/Jcm.42.10.4780-4787.2004  0.349
2004 Ackermann MR, Gallup JM, Zabner J, Evans RB, Brockus CW, Meyerholz DK, Grubor B, Brogden KA. Differential expression of sheep beta-defensin-1 and -2 and interleukin 8 during acute Mannheimia haemolytica pneumonia. Microbial Pathogenesis. 37: 21-7. PMID 15194156 DOI: 10.1016/J.Micpath.2004.04.003  0.308
2004 Grubor B, Gallup JM, Meyerholz DK, Crouch EC, Evans RB, Brogden KA, Lehmkuhl HD, Ackermann MR. Enhanced surfactant protein and defensin mRNA levels and reduced viral replication during parainfluenza virus type 3 pneumonia in neonatal lambs. Clinical and Diagnostic Laboratory Immunology. 11: 599-607. PMID 15138188 DOI: 10.1128/Cdli.11.3.599-607.2004  0.33
Low-probability matches (unlikely to be authored by this person)
2012 Shelton DN, Fornalik H, Neff T, Park SY, Bender D, DeGeest K, Liu X, Xie W, Meyerholz DK, Engelhardt JF, Goodheart MJ. The role of LEF1 in endometrial gland formation and carcinogenesis. Plos One. 7: e40312. PMID 22792274 DOI: 10.1371/Journal.Pone.0040312  0.3
2023 Yuan F, Gasser GN, Lemire E, Montoro DT, Jagadeesh K, Zhang Y, Duan Y, Ievlev V, Wells KL, Rotti PG, Shahin W, Winter M, Rosen BH, Evans I, Cai Q, ... ... Meyerholz DK, et al. Transgenic ferret models define pulmonary ionocyte diversity and function. Nature. PMID 37730992 DOI: 10.1038/s41586-023-06549-9  0.299
2007 Itoh T, Iwashita S, Cohen MB, Meyerholz DK, Linn S. Ddb2 is a haploinsufficient tumor suppressor and controls spontaneous germ cell apoptosis. Human Molecular Genetics. 16: 1578-86. PMID 17468495 DOI: 10.1093/Hmg/Ddm107  0.299
2019 Chandra L, Borcherding DC, Kingsbury D, Atherly T, Ambrosini YM, Bourgois-Mochel A, Yuan W, Kimber M, Qi Y, Wang Q, Wannemuehler M, Ellinwood NM, Snella E, Martin M, Skala M, ... Meyerholz D, et al. Derivation of adult canine intestinal organoids for translational research in gastroenterology. Bmc Biology. 17: 33. PMID 30975131 DOI: 10.1186/S12915-019-0652-6  0.297
2017 Vijay R, Fehr AR, Janowski AM, Athmer J, Wheeler DL, Grunewald M, Sompallae R, Kurup SP, Meyerholz DK, Sutterwala FS, Narumiya S, Perlman S. Virus-induced inflammasome activation is suppressed by prostaglandin D2/DP1 signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 28630327 DOI: 10.1073/Pnas.1704099114  0.295
2018 Diehl L, Meyerholz DK, Day MJ, Affolter VK. Pathology and Pathogenesis of Immune-Mediated Diseases of Animals. Veterinary Pathology. 55: 5-7. PMID 29254471 DOI: 10.1177/0300985817739091  0.295
2014 Sieren JC, Meyerholz DK, Wang XJ, Davis BT, Newell JD, Hammond E, Rohret JA, Rohret FA, Struzynski JT, Goeken JA, Naumann PW, Leidinger MR, Taghiyev A, Van Rheeden R, Hagen J, et al. Development and translational imaging of a TP53 porcine tumorigenesis model. The Journal of Clinical Investigation. 124: 4052-66. PMID 25105366 DOI: 10.1172/Jci75447  0.295
2009 Meyerholz DK, Griffin MA, Castilow EM, Varga SM. Comparison of histochemical methods for murine eosinophil detection in an RSV vaccine-enhanced inflammation model. Toxicologic Pathology. 37: 249-55. PMID 19181630 DOI: 10.1177/0192623308329342  0.293
2012 Olivier AK, Yi Y, Sun X, Sui H, Liang B, Hu S, Xie W, Fisher JT, Keiser NW, Lei D, Zhou W, Yan Z, Li G, Evans TI, Meyerholz DK, et al. Abnormal endocrine pancreas function at birth in cystic fibrosis ferrets. The Journal of Clinical Investigation. 122: 3755-68. PMID 22996690 DOI: 10.1172/Jci60610  0.293
2009 Bouley D, Meyerholz D, Sellers R, Boyd K, Perle KL. Where's the mouse pathology training? Veterinary Pathology. 46: 1245-1247. PMID 19890103 DOI: 10.1354/Vp.09-Vp-0185-B-Com  0.293
2020 Swier VJ, White KA, Meyerholz DK, Chefdeville A, Khanna R, Sieren JC, Quelle DE, Weimer JM. Validating indicators of CNS disorders in a swine model of neurological disease. Plos One. 15: e0228222. PMID 32074109 DOI: 10.1371/Journal.Pone.0228222  0.292
2015 Singh MV, Cicha MZ, Meyerholz DK, Chapleau MW, Abboud FM. Dual Activation of TRIF and MyD88 Adaptor Proteins by Angiotensin II Evokes Opposing Effects on Pressure, Cardiac Hypertrophy, and Inflammatory Gene Expression. Hypertension. 66: 647-56. PMID 26195481 DOI: 10.1161/Hypertensionaha.115.06011  0.291
2011 Kondratowicz AS, Lennemann NJ, Sinn PL, Davey RA, Hunt CL, Moller-Tank S, Meyerholz DK, Rennert P, Mullins RF, Brindley M, Sandersfeld LM, Quinn K, Weller M, McCray PB, Chiorini J, et al. T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus. Proceedings of the National Academy of Sciences of the United States of America. 108: 8426-31. PMID 21536871 DOI: 10.1073/Pnas.1019030108  0.291
2013 Simons AL, Lu P, Gibson-Corley KN, Robinson RA, Meyerholz DK, Colgan JD. The Justy mutant mouse strain produces a spontaneous murine model of salivary gland cancer with myoepithelial and basal cell differentiation. Laboratory Investigation; a Journal of Technical Methods and Pathology. 93: 711-9. PMID 23608756 DOI: 10.1038/Labinvest.2013.62  0.291
2020 Meyerholz DK, Beck AP. Adiposity of the B6 Mouse Lung The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07049  0.289
2011 Berquam-Vrieze KE, Nannapaneni K, Brett BT, Holmfeldt L, Ma J, Zagorodna O, Jenkins NA, Copeland NG, Meyerholz DK, Knudson CM, Mullighan CG, Scheetz TE, Dupuy AJ. Cell of origin strongly influences genetic selection in a mouse model of T-ALL. Blood. 118: 4646-56. PMID 21828136 DOI: 10.1182/Blood-2011-03-343947  0.289
2010 Lazic T, Matic M, Gallup JM, Van Geelen A, Meyerholz DK, Grubor B, Imerman PM, de-Macedo MM, Ackermann MR. Effects of nicotine on pulmonary surfactant proteins A and D in ovine lung epithelia. Pediatric Pulmonology. 45: 255-62. PMID 20131324 DOI: 10.1002/Ppul.21153  0.288
2002 Meyerholz DK, Stabel TJ, Ackermann MR, Carlson SA, Jones BD, Pohlenz J. Early epithelial invasion by Salmonella enterica serovar Typhimurium DT104 in the swine ileum. Veterinary Pathology. 39: 712-20. PMID 12450202 DOI: 10.1354/Vp.39-6-712  0.287
2013 Rogers LM, Olivier AK, Meyerholz DK, Dupuy AJ. Adaptive immunity does not strongly suppress spontaneous tumors in a Sleeping Beauty model of cancer. Journal of Immunology (Baltimore, Md. : 1950). 190: 4393-9. PMID 23475219 DOI: 10.4049/Jimmunol.1203227  0.287
2013 Rogers LM, Riordan JD, Swick BL, Meyerholz DK, Dupuy AJ. Ectopic expression of Zmiz1 induces cutaneous squamous cell malignancies in a mouse model of cancer. The Journal of Investigative Dermatology. 133: 1863-9. PMID 23426136 DOI: 10.1038/Jid.2013.77  0.286
2017 Barr JY, Wang X, Meyerholz DK, Lieberman SM. CD8 T cells contribute to lacrimal gland pathology in the nonobese diabetic mouse model of Sjögren syndrome. Immunology and Cell Biology. PMID 28465508 DOI: 10.1038/Icb.2017.38  0.286
2020 Meyerholz DK, Fiege JE, Block KE, Pierson M, Pape KA, Jenkins MK, Hamilton SE, Masopust D, Langlois RA. Dirty Mice Have Altered Influenza A Virus Clearance And Lesions Compared To SPF Mice: A Proposed Model For Study Of Vaccine Response In Humans The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04770  0.286
2010 Hunninghake GW, Doerschug KC, Nymon AB, Schmidt GA, Meyerholz DK, Ashare A. Insulin-like Growth Factor–1 Levels Contribute to the Development of Bacterial Translocation in Sepsis American Journal of Respiratory and Critical Care Medicine. 182: 517-525. PMID 20413631 DOI: 10.1164/Rccm.200911-1757Oc  0.285
2014 Sieren JC, Wang X, Davis B, Newell JD, Hammond E, Rohret J, Rohret F, Struzynski J, Goeken A, Naumann P, Leidinger M, Hagen J, Rheeden RV, Darbro BW, Quelle DE, ... Meyerholz DK, et al. Abstract LB-162: Translational imaging of tumorigenesis in aTP53porcine cancer model Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-162  0.284
2013 Scroggins SM, Olivier AK, Meyerholz DK, Schlueter AJ. Characterization of Regulatory Dendritic Cells That Mitigate Acute Graft-versus-Host Disease in Older Mice Following Allogeneic Bone Marrow Transplantation Plos One. 8. PMID 24040397 DOI: 10.1371/Journal.Pone.0075158  0.284
2002 Wu MT, Carlson SA, Meyerholz DK. Cytopathic effects observed upon expression of a repressed collagenase gene present in Salmonella and related pathogens: mimicry of a cytotoxin from multiple antibiotic-resistant Salmonella enterica serotype Typhimurium phagetype DT104 Microbial Pathogenesis. 33: 279-287. PMID 12495674 DOI: 10.1006/Mpat.2002.0535  0.284
2012 Yu S, Zhou X, Steinke FC, Liu C, Chen SC, Zagorodna O, Jing X, Yokota Y, Meyerholz DK, Mullighan CG, Knudson CM, Zhao DM, Xue HH. The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy. Immunity. 37: 813-26. PMID 23103132 DOI: 10.1016/J.Immuni.2012.08.009  0.283
2020 Zheng J, Sariol A, Meyerholz D, Zhang Q, Abrahante Lloréns JE, Narumiya S, Perlman S. Prostaglandin D2 signaling in dendritic cells is critical for the development of EAE. Journal of Autoimmunity. 102508. PMID 32624353 DOI: 10.1016/J.Jaut.2020.102508  0.282
2022 Thurman AL, Li X, Villacreses R, Yu W, Gong H, Mather SE, Romano-Ibarra GS, Meyerholz DK, Stoltz DA, Welsh MJ, Thornell IM, Zabner J, Pezzulo AA. A Single-Cell Atlas of Large and Small Airways at Birth in a Porcine Model of Cystic Fibrosis. American Journal of Respiratory Cell and Molecular Biology. PMID 35235762 DOI: 10.1165/rcmb.2021-0499OC  0.282
2009 Welsh MJ, Rogers CS, Stoltz DA, Meyerholz DK, Prather RS. Development of a porcine model of cystic fibrosis. Transactions of the American Clinical and Climatological Association. 120: 149-62. PMID 19768173  0.281
2007 Lazic T, Wyatt TA, Matic M, Meyerholz DK, Grubor B, Gallup JM, Kersting KW, Imerman PM, Almeida-De-Macedo M, Ackermann MR. Maternal alcohol ingestion reduces surfactant protein A expression by preterm fetal lung epithelia. Alcohol (Fayetteville, N.Y.). 41: 347-55. PMID 17889311 DOI: 10.1016/J.Alcohol.2007.07.006  0.28
2007 Meyerholz DK, Edsen M, Coleman RA, Cook RT, Legge KL. Chronic ethanol ingestion in mice enhances influenza A H1N1 pulmonary lesions The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A9-A  0.28
2020 Beck AP, Meyerholz DK. Evolving challenges to model human diseases for translational research. Cell and Tissue Research. 380: 305-311. PMID 32130478 DOI: 10.1007/S00441-019-03134-3  0.279
2016 Hammond E, Newell JD, Dilger SK, Stoyles N, Morgan J, Sieren JP, Thedens DR, Hoffman EA, Meyerholz DK, Sieren JC. Computed Tomography and Magnetic Resonance Imaging for Longitudinal Characterization of Lung Structure Changes in a Yucatan Miniature Pig Silicosis Model. Toxicologic Pathology. PMID 26839326 DOI: 10.1177/0192623315622303  0.279
2011 Yuan Z, Meyerholz DK, Twait EC, Kempuraj D, Williard DE, Samuel I. Systemic Inflammation with Multiorgan Dysfunction Is the Cause of Death in Murine Ligation-Induced Acute Pancreatitis Journal of Gastrointestinal Surgery. 15: 1670-1678. PMID 21800226 DOI: 10.1007/S11605-011-1643-2  0.278
2020 Uthoff J, Larson J, Sato TS, Hammond E, Schroeder KE, Rohret F, Rogers CS, Quelle DE, Darbro BW, Khanna R, Weimer JM, Meyerholz DK, Sieren JC. Longitudinal phenotype development in a minipig model of neurofibromatosis type 1. Scientific Reports. 10: 5046. PMID 32193437 DOI: 10.1038/S41598-020-61251-4  0.278
2013 Kempuraj D, Twait EC, Williard DE, Yuan Z, Meyerholz DK, Samuel I. The Novel Cytokine Interleukin-33 Activates Acinar Cell Proinflammatory Pathways and Induces Acute Pancreatic Inflammation in Mice Plos One. 8. PMID 23418608 DOI: 10.1371/Journal.Pone.0056866  0.278
2012 Sui H, Brooks L, Klesney-Tait J, Olivier A, Meyerholz D, Zavazava N, Engelhardt J, Parekh K. 290 Ferret Lung Transplant: An Orthotopic Model for Obliterative Bronchiolitis The Journal of Heart and Lung Transplantation. 31: S104-S105. DOI: 10.1016/J.Healun.2012.01.298  0.278
2014 Hernandez FJ, Huang L, Olson ME, Powers KM, Hernandez LI, Meyerholz DK, Thedens DR, Behlke MA, Horswill AR, McNamara JO. Noninvasive imaging of Staphylococcus aureus infections with a nuclease-activated probe. Nature Medicine. 20: 301-6. PMID 24487433 DOI: 10.1038/Nm.3460  0.276
2011 Lazic T, Sow FB, Van Geelen A, Meyerholz DK, Gallup JM, Ackermann MR. Exposure to ethanol during the last trimester of pregnancy alters the maturation and immunity of the fetal lung. Alcohol (Fayetteville, N.Y.). 45: 673-80. PMID 21163613 DOI: 10.1016/J.Alcohol.2010.11.001  0.274
2004 Meyerholz DK, Gallup JM, Grubor BM, Evans RB, Tack BF, McCray PB, Ackermann MR. Developmental expression and distribution of sheep beta-defensin-2. Developmental and Comparative Immunology. 28: 171-8. PMID 12969802 DOI: 10.1016/S0145-305X(03)00105-8  0.273
2017 McCue MD, Passement CA, Meyerholz DK. Maintenance of Distal Intestinal Structure in the Face of Prolonged Fasting: A Comparative Examination of Species From Five Vertebrate Classes. Anatomical Record (Hoboken, N.J. : 2007). 300: 2208-2219. PMID 28941363 DOI: 10.1002/Ar.23691  0.272
2016 Ibberson CB, Parlet CP, Kwiecinski J, Crosby HA, Meyerholz DK, Horswill AR. Hyaluronan modulation impacts Staphylococcus aureus biofilm infection. Infection and Immunity. PMID 27068096 DOI: 10.1128/Iai.01418-15  0.272
2006 Grubor B, Meyerholz DK, Lazic T, DeMacedo MM, Derscheid RJ, Hostetter JM, Gallup JM, DeMartini JC, Ackermann MR. Regulation of surfactant protein and defensin mRNA expression in cultured ovine type II pneumocytes by all-trans retinoic acid and VEGF. International Journal of Experimental Pathology. 87: 393-403. PMID 16965567 DOI: 10.1111/J.1365-2613.2006.00494.X  0.272
2008 George CL, Goss KL, Meyerholz DK, Lamb FS, Snyder JM. Surfactant-associated protein A provides critical immunoprotection in neonatal mice. Infection and Immunity. 76: 380-90. PMID 17967856 DOI: 10.1128/Iai.01043-07  0.272
2014 Gibson-Corley KN, Rogers LM, Goeken A, Dupuy AJ, Meyerholz DK. Keratoacanthoma Pathobiology in Mouse Models. Diseases (Basel, Switzerland). 2: 106-119. PMID 25309748 DOI: 10.3390/Diseases2020106  0.269
2003 Meyerholz DK, Stabel TJ. Comparison of Early Ileal Invasion by Salmonella enterica Serovars Choleraesuis and Typhimurium Veterinary Pathology. 40: 371-375. PMID 12824508 DOI: 10.1354/Vp.40-4-371  0.268
2017 Stevens JW, Meyerholz DK, Neighbors JD, Morcuende JA. 5'-Methylschweinfurthin G reduces chondrosarcoma tumor growth. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 28960476 DOI: 10.1002/Jor.23753  0.267
2021 Li K, Meyerholz DK, Bartlett JA, McCray PB. The TMPRSS2 Inhibitor Nafamostat Reduces SARS-CoV-2 Pulmonary Infection in Mouse Models of COVID-19. Mbio. e0097021. PMID 34340553 DOI: 10.1128/mBio.00970-21  0.267
2011 Yuan Z, Meyerholz D, Williard D, Twait E, Duraisamy K, Samuel I. Systemic Inflammation With Multiorgan Dysfunction is the Cause of Death in Murine Pancreatic Duct Ligation-Induced Acute Pancreatitis Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)64264-9  0.264
2018 White KA, Swier VJ, Cain JT, Kohlmeyer JL, Meyerholz DK, Tanas MR, Uthoff J, Hammond E, Li H, Rohret FA, Goeken A, Chan CH, Leidinger MR, Umesalma S, Wallace MR, et al. A porcine model of neurofibromatosis type 1 that mimics the human disease. Jci Insight. 3. PMID 29925695 DOI: 10.1172/Jci.Insight.120402  0.263
2010 Lu P, Hankel IL, Knisz J, Marquardt A, Chiang MY, Grosse J, Constien R, Meyer T, Schroeder A, Zeitlmann L, Al-Alem U, Friedman AD, Elliott EI, Meyerholz DK, Waldschmidt TJ, et al. The Justy mutation identifies Gon4-like as a gene that is essential for B lymphopoiesis. The Journal of Experimental Medicine. 207: 1359-67. PMID 20530203 DOI: 10.1084/Jem.20100147  0.262
2001 Carlson SA, Meyerholz DK, Stabel TJ, Jones BD. Secretion of a putative cytotoxin in multiple antibiotic resistant Salmonella enterica serotype Typhimurium phagetype DT104. Microbial Pathogenesis. 31: 201-4. PMID 11562173 DOI: 10.1006/Mpat.2001.0461  0.262
2019 Singh MV, Cicha MZ, Nunez S, Meyerholz DK, Chapleau MW, Abboud FM. Angiotensin II-induced Hypertension and Cardiac Hypertrophy are Differentially Mediated by TLR3- and TLR4-Dependent Pathways. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30793936 DOI: 10.1152/Ajpheart.00697.2018  0.26
2021 Zheng J, Meyerholz D, Wong LR, Gelb M, Murakami M, Perlman S. Coronavirus-specific antibody production in middle-aged mice requires phospholipase A2G2D. The Journal of Clinical Investigation. 131. PMID 34060490 DOI: 10.1172/JCI147201  0.259
2018 Meyerholz DK, Beck AP. Principles and approaches for reproducible scoring of tissue stains in research. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 29849125 DOI: 10.1038/S41374-018-0057-0  0.258
2004 Meyerholz DK, Caston SS, Haynes JS. Congenital fetal rhabdomyoma in a foal. Veterinary Pathology. 41: 518-20. PMID 15347826 DOI: 10.1354/Vp.41-5-518  0.257
2018 Brayton CF, Boyd KL, Everitt JL, Meyerholz DK, Treuting PM, Bolon B. An Introduction to Pathology in Biomedical Research: A Mission-Critical Specialty for Reproducibility and Rigor in Translational Research. Ilar Journal. 59: 1-3. PMID 31329902 DOI: 10.1093/Ilar/Ilz008  0.257
2007 Meyerholz DK, Samuel I. Morphologic characterization of early ligation-induced acute pancreatitis in rats. American Journal of Surgery. 194: 652-658. PMID 17936429 DOI: 10.1016/J.Amjsurg.2007.07.014  0.257
2010 Samuel I, Yuan Z, Meyerholz DK, Twait E, Williard DE, Kempuraj D. A Novel Model of Severe Gallstone Pancreatitis: Murine Pancreatic Duct Ligation Results in Systemic Inflammation and Substantial Mortality Pancreatology. 10: 536-544. PMID 20975317 DOI: 10.1159/000320776  0.256
2020 Ostedgaard LS, Price MP, Whitworth KM, Abou Alaiwa MH, Fischer AJ, Warrier A, Samuel M, Spate LD, Allen PD, Hilkin BM, Romano Ibarra GS, Ortiz Bezara ME, Goodell BJ, Mather SE, Powers LS, ... ... Meyerholz DK, et al. Lack of airway submucosal glands impairs respiratory host defenses. Elife. 9. PMID 33026343 DOI: 10.7554/eLife.59653  0.255
2012 Rollins KE, Meyerholz DK, Johnson GD, Capparella AP, Loew SS. A forensic investigation into the etiology of bat mortality at a wind farm: barotrauma or traumatic injury? Veterinary Pathology. 49: 362-71. PMID 22291071 DOI: 10.1177/0300985812436745  0.255
2014 Sieren JC, Quelle D, Meyerholz DK, Rogers CS. Porcine cancer models for translational oncology. Molecular & Cellular Oncology. 1: e969626. PMID 27308376 DOI: 10.4161/23723548.2014.969626  0.252
2014 Dassie JP, Hernandez LI, Thomas GS, Long ME, Rockey WM, Howell CA, Chen Y, Hernandez FJ, Liu XY, Wilson ME, Allen LA, Vaena DA, Meyerholz DK, Giangrande PH. Targeted inhibition of prostate cancer metastases with an RNA aptamer to prostate-specific membrane antigen. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1910-22. PMID 24954476 DOI: 10.1038/Mt.2014.117  0.252
2019 Umesalma S, Kaemmer CA, Kohlmeyer JL, Letney BL, Schab AM, Reilly JA, Sheehy RM, Hagen J, Tiwari N, Zhan F, Leidinger MR, O'Dorisio TM, Dillon JS, Merrill RA, Meyerholz DK, et al. RABL6A inhibits tumor-suppressive PP2A/AKT signaling to drive pancreatic neuroendocrine tumor growth. The Journal of Clinical Investigation. PMID 30721156 DOI: 10.1172/Jci123049  0.251
2016 Ali A, Derar D, El-Manakhly EM, Al-Sobayil F, Piersigilli A, Meyerholz DK. A congenital case of intermediate-type fetal rhabdomyoma in an Ardi goat kid Journal of Histotechnology. 39: 17-20. DOI: 10.1080/01478885.2015.1133009  0.251
2010 Rogers LM, Swick BL, Meyerholz DK, Dupuy AJ. Abstract 249: A Sleeping Beauty screen in mice identifies Zmiz1 as a candidate cancer gene in human squamous cell carcinomas Cellular and Molecular Biology. 70: 249-249. DOI: 10.1158/1538-7445.Am10-249  0.25
2021 Li X, Villacreses R, Thornell IM, Noriega J, Mather S, Brommel CM, Lu L, Zabner A, Ehler A, Meyerholz DK, Stoltz DA, Zabner J. V-type ATPase Mediates Airway Surface Liquid Acidification in Pig Small Airway Epithelial Cells. American Journal of Respiratory Cell and Molecular Biology. PMID 33789071 DOI: 10.1165/rcmb.2020-0349OC  0.249
2002 Meyerholz DK, Stabel TJ, Cheville NF. Segmented filamentous bacteria interact with intraepithelial mononuclear cells. Infection and Immunity. 70: 3277-3280. PMID 12011024 DOI: 10.1128/Iai.70.6.3277-3280.2002  0.249
2009 Dassie JP, Liu XY, Thomas GS, Whitaker RM, Thiel KW, Stockdale KR, Meyerholz DK, McCaffrey AP, McNamara JO, Giangrande PH. Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors. Nature Biotechnology. 27: 839-49. PMID 19701187 DOI: 10.1038/Nbt.1560  0.249
2017 Singh MV, Cicha MZ, Kumar S, Meyerholz DK, Irani K, Chapleau MW, Abboud FM. Abnormal CD161(+) Immune Cells and RORΓT Mediated Enhanced IL-17F Expression in Genetic Hypertension. The Journal of Allergy and Clinical Immunology. PMID 28093217 DOI: 10.1016/J.Jaci.2016.11.039  0.249
2018 Caswell JL, Bassel LL, Rothenburger JL, Gröne A, Sargeant JM, Beck AP, Ekman S, Gibson-Corley KN, Kuiken T, LaDouceur EEB, Meyerholz DK, Origgi FC, Posthaus H, Priestnall SL, Ressel L, et al. Observational Study Design in Veterinary Pathology, Part 2: Methodology. Veterinary Pathology. 300985818798121. PMID 30227783 DOI: 10.1177/0300985818798121  0.247
2019 Xing S, Gai K, Li X, Shao P, Zeng Z, Zhao X, Zhao X, Chen X, Paradee WJ, Meyerholz DK, Peng W, Xue HH. Tcf1 and Lef1 are required for the immunosuppressive function of regulatory T cells. The Journal of Experimental Medicine. PMID 30837262 DOI: 10.1084/Jem.20182010  0.246
2012 Olivier AK, Naumann P, Goeken A, Hochstedler C, Sturm M, Rodgers JR, Gibson-Corley KN, Meyerholz DK. Genetically modified species in research: Opportunities and challenges for the histology core laboratory. Journal of Histotechnology. 35: 63-67. PMID 22904582 DOI: 10.1179/2046023612Y.0000000003  0.246
2020 Zheng J, Wong LR, Li K, Verma AK, Ortiz M, Wohlford-Lenane C, Leidinger MR, Knudson CM, Meyerholz DK, McCray PB, Perlman S. COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice. Nature. PMID 33166988 DOI: 10.1038/s41586-020-2943-z  0.246
2010 McNamara AR, Zamba KD, Sokolich JC, Jaskille AD, Light TD, Griffin MA, Meyerholz DK. Apoptosis is differentially regulated by burn severity and dermal location. The Journal of Surgical Research. 162: 258-63. PMID 19439323 DOI: 10.1016/J.Jss.2009.01.038  0.246
2010 Gookin JL, Stone MR, Yaeger MJ, Meyerholz DK, Moisan P. Fluorescence in situ hybridization for identification of Tritrichomonas foetus in formalin-fixed and paraffin-embedded histological specimens of intestinal trichomonosis Veterinary Parasitology. 172: 139-143. PMID 20447769 DOI: 10.1016/J.Vetpar.2010.04.014  0.244
2019 Ebert SM, Dierdorff JM, Meyerholz DK, Bullard SA, Al-Zougbi A, DeLau AD, Tomcheck KC, Skopec ZP, Marcotte GR, Bodine SC, Adams CM. An Investigation of p53 in Skeletal Muscle Aging. Journal of Applied Physiology (Bethesda, Md. : 1985). PMID 31465716 DOI: 10.1152/Japplphysiol.00363.2019  0.243
2018 Meyerholz DK, Beck AP. Fundamental Concepts for Semiquantitative Tissue Scoring in Translational Research. Ilar Journal. 59: 13-17. PMID 30715381 DOI: 10.1093/Ilar/Ily025  0.243
2018 Caswell JL, Bassel LL, Rothenburger JL, Gröne A, Sargeant JM, Beck AP, Ekman S, Gibson-Corley KN, Kuiken T, LaDouceur EEB, Meyerholz DK, Origgi FC, Posthaus H, Priestnall SL, Ressel L, et al. Observational Study Design in Veterinary Pathology, Part 1: Study Design. Veterinary Pathology. 300985818785705. PMID 30071806 DOI: 10.1177/0300985818785705  0.242
2013 Case AJ, Madsen JM, Motto DG, Meyerholz DK, Domann FE. Manganese superoxide dismutase depletion in murine hematopoietic stem cells perturbs iron homeostasis, globin switching, and epigenetic control in erythrocyte precursor cells. Free Radical Biology & Medicine. 56: 17-27. PMID 23219873 DOI: 10.1016/J.Freeradbiomed.2012.11.018  0.242
2020 Zheng J, Roy Wong LY, Li K, Verma AK, Ortiz M, Wohlford-Lenane C, Leidinger MR, Knudson CM, Meyerholz DK, McCray PB, Perlman S. K18-hACE2 Mice for Studies of COVID-19 Treatments and Pathogenesis Including Anosmia. Biorxiv : the Preprint Server For Biology. PMID 32817939 DOI: 10.1101/2020.08.07.242073  0.242
2020 Meyerholz DK, Beck AP, Singh B. Innovative use of animal models to advance scientific research. Cell and Tissue Research. 380: 205-206. PMID 32307578 DOI: 10.1007/S00441-020-03210-Z  0.239
2019 Khanna R, Moutal A, White KA, Chefdeville A, Negrao de Assis P, Cai S, Swier VJ, Bellampalli SS, Giunta MD, Darbro BW, Quelle DE, Sieren JC, Wallace MR, Rogers CS, Meyerholz DK, et al. Assessment of nociception and related quality of life measures in a porcine model of Neurofibromatosis type 1. Pain. PMID 31246731 DOI: 10.1097/J.Pain.0000000000001648  0.238
2012 Case AJ, Madsen JM, Motto DG, Meyerholz DK, Domann FE. Disruption of Mitochondrial Superoxide Flux Causes Abnormal Heme Synthesis and Hemoglobin Gene Regulation in Erythroid Precursor Cells Free Radical Biology and Medicine. 53: S17. DOI: 10.1016/J.Freeradbiomed.2012.10.035  0.238
2009 McGill J, Meyerholz D, Young B, Coleman RA, Schlueter A, Waldschmidt TJ, Cook RT, Legge KL. Fetal exposure to ethanol has long-term effects on influenza viral immunity and disease severity Alcohol. 43: 669. DOI: 10.1016/J.Alcohol.2009.09.016  0.237
2018 Meyerholz DK, Tintle NL, Beck AP. Common Pitfalls in Analysis of Tissue Scores. Veterinary Pathology. 300985818794250. PMID 30131009 DOI: 10.1177/0300985818794250  0.237
2020 Ortiz Bezara ME, Thurman A, Pezzulo AA, Leidinger MR, Klesney-Tait JA, Karp PH, Tan P, Wohlford-Lenane C, McCray PB, Meyerholz DK. Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract. Biorxiv : the Preprint Server For Biology. PMID 32577664 DOI: 10.1101/2020.04.22.056127  0.235
2014 Yu S, Zhou X, Steinke FC, Liu C, Chen SC, Zagorodna O, Jing X, Yokota Y, Meyerholz DK, Mullighan CG, Knudson CM, Zhao DM, Xue HH. Erratum to The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy [Immunityn 37, (November 16, 2012), 813-826] Immunity. 40. DOI: 10.1016/J.Immuni.2013.12.001  0.234
2015 Stoltz DA, Meyerholz DK, Welsh MJ. Origins of cystic fibrosis lung disease. The New England Journal of Medicine. 372: 1574-5. PMID 25875271 DOI: 10.1056/NEJMc1502191  0.231
2021 Zarei K, Meyerholz DK, Stoltz DA. Early intrahepatic duct defects in a cystic fibrosis porcine model. Physiological Reports. 9: e14978. PMID 34288572 DOI: 10.14814/phy2.14978  0.23
2020 Skurski J, Penniman CM, Geesala R, Dixit G, Pulipati P, Bhardwaj G, Meyerholz DK, Issuree PD, O'Neill BT, Maretzky T. Loss of iRhom2 accelerates fat gain and insulin resistance in diet-induced obesity despite reduced adipose tissue inflammation. Metabolism: Clinical and Experimental. 154194. PMID 32135161 DOI: 10.1016/J.Metabol.2020.154194  0.23
2017 Kohl KD, Oakeson KF, Dunn D, Meyerholz DK, Dale C, Weiss RB, Dearing MD. Patterns of host gene expression associated with harboring a foregut microbial community. Bmc Genomics. 18: 697. PMID 28874116 DOI: 10.1186/S12864-017-4101-Z  0.23
2015 Ebert SM, Dyle MC, Bullard SA, Dierdorff JM, Murry DJ, Fox DK, Bongers KS, Lira VA, Meyerholz DK, Talley JJ, Adams CM. Identification and Small Molecule Inhibition of an ATF4-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy. The Journal of Biological Chemistry. PMID 26338703 DOI: 10.1074/Jbc.M115.681445  0.229
2022 El-Kafrawy SA, Odle A, Abbas AT, Hassan AM, Abdel-Dayem UA, Qureshi AK, Wong LR, Zheng J, Meyerholz DK, Perlman S, Zumla A, Azhar EI. SARS-CoV-2-specific immunoglobulin Y antibodies are protective in infected mice. Plos Pathogens. 18: e1010782. PMID 36121829 DOI: 10.1371/journal.ppat.1010782  0.229
2013 Gibson-Corley KN, Olivier AK, Meyerholz DK. Principles for Valid Histopathologic Scoring in Research Veterinary Pathology. 50: 1007-1015. PMID 23558974 DOI: 10.1177/0300985813485099  0.228
2009 Meyerholz DK, Piester TL, McNamara AR, Sokolich JC, Jaskille AD, Orion KC, Zamba KD, Light TD. Pharmacologic modification to resuscitation fluid after thermal injury--is drotrecogin alfa the answer to arrest burn depth progression? Journal of Trauma-Injury Infection and Critical Care. 67: 996-1003. PMID 19901660 DOI: 10.1097/Ta.0B013E3181B83B3B  0.228
2013 Young AG, Neff TL, Samuelson M, Meyerholz DK, Dupuy AJ, Goodheart MJ. The generation of a novel spontaneous transgenic mouse model of node positive metastatic vulvar cancer Gynecologic Oncology. 131: 261. DOI: 10.1016/J.Ygyno.2013.07.038  0.228
2008 Meyerholz DK, Edsen-Moore M, McGill J, Coleman RA, Cook RT, Legge KL. Response to Comment on “Chronic Alcohol Consumption Increases the Severity of Murine Influenza Virus Infections” The Journal of Immunology. 181: 5813.2-5814. DOI: 10.4049/Jimmunol.181.9.5813-A  0.227
2016 Harwani SC, Ratcliff J, Sutterwala FS, Ballas ZK, Meyerholz DK, Chapleau MW, Abboud F. Nicotine Mediates CD161a+ Renal Macrophage Infiltration and Premature Hypertension in the Spontaneously Hypertensive Rat. Circulation Research. PMID 27660287 DOI: 10.1161/Circresaha.116.309402  0.227
2018 Ward JM, Meyerholz DK. Citation Index Is Not Critically Important to Veterinary Pathology, Medicine, and Research. Veterinary Pathology. 55: 595-596. PMID 29890927 DOI: 10.1177/0300985818758472  0.227
2011 Bolon B, Altrock B, Barthold SW, Baumgarth N, Besselsen D, Boivin G, Boyd KL, Brayton C, Cardiff RD, Couto S, Eaton KA, Foreman O, Griffey SM, La Perle K, Lairmore MD, ... ... Meyerholz DK, et al. Advancing translational research. Science (New York, N.Y.). 331: 1516-7. PMID 21436422 DOI: 10.1126/Science.331.6024.1516-B  0.227
2016 Paharik AE, Salgado-Pabon W, Meyerholz DK, White MJ, Schlievert PM, Horswill AR. The Spl Serine Proteases Modulate Staphylococcus aureus Protein Production and Virulence in a Rabbit Model of Pneumonia. Msphere. 1. PMID 27747296 DOI: 10.1128/mSphere.00208-16  0.226
2016 Meyerholz DK, Piersigilli A. Animal models: Software for study design falls short. Nature. 532: 177. PMID 27075088 DOI: 10.1038/532177C  0.224
2017 Chakravarti B, Yang J, Ahlers-Dannen KE, Luo Z, Flaherty HA, Meyerholz DK, Anderson ME, Fisher RA. Essentiality of Regulator of G Protein Signaling 6 and Oxidized Ca(2+)/Calmodulin-Dependent Protein Kinase II in Notch Signaling and Cardiovascular Development. Journal of the American Heart Association. 6. PMID 29079565 DOI: 10.1161/Jaha.117.007038  0.224
2005 Meyerholz DK, Hostetter SJ. Unilateral perinephric pseudocyst secondary to hydronephrosis in a C57BL/6J mouse Veterinary Pathology. 42: 496-498. PMID 16006610 DOI: 10.1354/Vp.42-4-496  0.224
2020 Kohlmeyer JL, Kaemmer CA, Pulliam C, Maharjan CK, Moreno Samayoa A, Major HJ, Cornick KE, Knepper-Adrian V, Khanna R, Sieren JC, Leidinger M, Meyerholz DK, Zamba KD, Weimer J, Dodd RD, et al. RABL6A is an essential driver of MPNSTs that negatively regulates the RB1 pathway and sensitizes tumor cells to CDK4/6 inhibitors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32086342 DOI: 10.1158/1078-0432.Ccr-19-2706  0.222
2011 Haverkamp JM, Charbonneau B, Crist SA, Meyerholz DK, Cohen MB, Snyder PW, Svensson RU, Henry MD, Wang HH, Ratliff TL. An inducible model of abacterial prostatitis induces antigen specific inflammatory and proliferative changes in the murine prostate. The Prostate. 71: 1139-50. PMID 21656824 DOI: 10.1002/Pros.21327  0.221
2012 Gibson-Corley KN, Hochstedler C, Sturm M, Rodgers J, Olivier AK, Meyerholz DK. Successful integration of the histology core laboratory in translational research Journal of Histotechnology. 35: 17-21. PMID 22904581 DOI: 10.1179/2046023612Y.0000000001  0.22
2017 Henze M, Anderson R, Wong F, Weiss R, Divekar A, Meyerholz D, Ahmad F, Green E. Cardiac muscle function across the natural history of a genetic minipig model of hypertrophic cardiomyopathy Journal of Molecular and Cellular Cardiology. 112: 166. DOI: 10.1016/J.Yjmcc.2017.07.106  0.219
2016 Boi SK, Buchta CM, Pearson NA, Francis MB, Meyerholz DK, Grobe JL, Norian LA. Obesity alters immune and metabolic profiles: New insight from obese-resistant mice on high-fat diet. Obesity (Silver Spring, Md.). PMID 27515998 DOI: 10.1002/Oby.21620  0.219
2007 Dee FR, Meyerholz DK. Teaching medical pathology in the twenty-first century: virtual microscopy applications. Journal of Veterinary Medical Education. 34: 431-436. PMID 18287469 DOI: 10.3138/Jvme.34.4.431  0.215
2021 Roy Wong LY, Zheng J, Wilhelmsen K, Li K, Ortiz ME, Schnicker NJ, Pezzulo AA, Szachowicz PJ, Klumpp K, Aswad F, Rebo J, Narumiya S, Murakami M, Meyerholz DK, Fortney K, et al. Eicosanoid signaling as a therapeutic target in middle-aged mice with severe COVID-19. Biorxiv : the Preprint Server For Biology. PMID 33907749 DOI: 10.1101/2021.04.20.440676  0.21
2024 Li K, Verma A, Li P, Ortiz ME, Hawkins GM, Schnicker NJ, Szachowicz PJ, Pezullo A, Wohlford-Lenane CL, Kicmal T, Meyerholz DK, Gallagher T, Perlman S, McCray PB. Adaptation of SARS-CoV-2 to ACE2 mice reveals new spike residues that drive mouse infection. Journal of Virology. e0151023. PMID 38168680 DOI: 10.1128/jvi.01510-23  0.21
2016 Piersigilli A, Meyerholz DK. The “Naked Truth”: Naked Mole-Rats Do Get Cancer Veterinary Pathology. 53: 519-520. PMID 27000397 DOI: 10.1177/0300985816638431  0.208
2019 Raikwar NS, Braverman C, Snyder PM, Fenton RA, Meyerholz DK, Abboud FM, Harwani SC. Renal Denervation and CD161a Immune Ablation Prevent Cholinergic Hypertension and Renal Sodium Retention. American Journal of Physiology. Heart and Circulatory Physiology. PMID 31172810 DOI: 10.1152/Ajpheart.00234.2019  0.207
2017 Meyerholz DK, Flaherty HA. The Evolving Significance and Future Relevance of the Impact Factor. Veterinary Pathology. 54: 721-722. PMID 28622493 DOI: 10.1177/0300985817690209  0.206
2023 Meyerholz DK, Leidinger MR, Adam Goeken J, Businga TR, Vizuett S, Akers A, Evans I, Zhang Y, Engelhardt JF. Immunohistochemical detection of MUC5AC and MUC5B mucins in ferrets. Bmc Research Notes. 16: 111. PMID 37349833 DOI: 10.1186/s13104-023-06388-x  0.206
2021 Dampalla CS, Zheng J, Perera KD, Wong LR, Meyerholz DK, Nguyen HN, Kashipathy MM, Battaile KP, Lovell S, Kim Y, Perlman S, Groutas WC, Chang KO. Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34210738 DOI: 10.1073/pnas.2101555118  0.205
2023 Wong L-YR, Odle A, Luhmann E, Wu DC, Wang Y, Teo QW, Ptak C, Sariol A, Lowery S, Mack M, Meyerholz DK, Wu NC, Radoshevich L, Perlman S. Contrasting roles of MERS-CoV and SARS-CoV-2 internal proteins in pathogenesis in mice. Mbio. e0247623. PMID 37882568 DOI: 10.1128/mbio.02476-23  0.203
2023 Silva EE, Moioffer SJ, Hassert M, Berton RR, Smith MG, van de Wall S, Meyerholz DK, Griffith TS, Harty JT, Badovinac VP. Defining Parameters That Modulate Susceptibility and Protection to Respiratory Murine Coronavirus MHV1 Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 38149923 DOI: 10.4049/jimmunol.2300434  0.201
2009 Meyerholz DK, Piester TL, Sokolich JC, Zamba GKD, Light TD. Morphological parameters for assessment of burn severity in an acute burn injury rat model International Journal of Experimental Pathology. 90: 26-33. PMID 19200248 DOI: 10.1111/J.1365-2613.2008.00617.X  0.201
2018 Uthoff J, Stefano FA, Panzer K, Darbro BW, Sato TS, Khanna R, Quelle DE, Meyerholz DK, Weimer J, Sieren JC. Radiomic Biomarkers Informative of Cancerous Transformation in Neurofibromatosis-1 Plexiform Tumors. Journal of Neuroradiology. Journal De Neuroradiologie. PMID 29958847 DOI: 10.1016/J.Neurad.2018.05.006  0.201
2004 Meyerholz DK, Haynes JS. Solitary retinal astrocytoma in a dog. Veterinary Pathology. 41: 177-8. PMID 15017032 DOI: 10.1354/Vp.41-2-177  0.199
2022 Wong LR, Zheng J, Wilhelmsen K, Li K, Ortiz ME, Schnicker NJ, Thurman A, Pezzulo AA, Szachowicz PJ, Li P, Pan R, Klumpp K, Aswad F, Rebo J, Narumiya S, ... ... Meyerholz DK, et al. Eicosanoid signaling blockade protects middle-aged mice from severe COVID-19. Nature. PMID 35314834 DOI: 10.1038/s41586-022-04630-3  0.198
2010 Rockey W, Walsh S, Liu X, Sunderland J, Meyerholz D, Thedens D, McNamara J, Schultz M, Giangrande P. Development of an RNA-based SPECT/CT Imaging Agent for Prostate Cancer International Journal of Radiation Oncology*Biology*Physics. 78: S163. DOI: 10.1016/J.Ijrobp.2010.07.402  0.191
2023 Kulhankova K, Traore S, Cheng X, Benk-Fortin H, Hallée S, Harvey M, Roberge J, Couture F, Kohli S, Gross TJ, Meyerholz DK, Rettig GR, Thommandru B, Kurgan G, Wohlford-Lenane C, et al. Shuttle peptide delivers base editor RNPs to rhesus monkey airway epithelial cells in vivo. Nature Communications. 14: 8051. PMID 38052872 DOI: 10.1038/s41467-023-43904-w  0.19
2023 Li P, Kim Y, Dampalla CS, Nhat Nguyen H, Meyerholz DK, Johnson DK, Lovell S, Groutas WC, Perlman S, Chang K-O. Potent 3CLpro inhibitors effective against SARS-CoV-2 and MERS-CoV in animal models by therapeutic treatment. Mbio. e0287823. PMID 38126789 DOI: 10.1128/mbio.02878-23  0.189
2021 Wong LR, Zheng J, Sariol A, Lowery S, Meyerholz DK, Gallagher T, Perlman S. Middle East respiratory syndrome coronavirus Spike protein variants exhibit geographic differences in virulence. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34099556 DOI: 10.1073/pnas.2102983118  0.188
2020 Meyerholz DK, Perlman S. Does common cold coronavirus infection protect against severe SARS-CoV2 disease? The Journal of Clinical Investigation. PMID 33216734 DOI: 10.1172/JCI144807  0.186
2022 Lynch TJ, Ahlers BA, Swatek AM, Ievlev V, Pai AC, Brooks L, Tang Y, Evans IA, Meyerholz DK, Engelhardt JF, Parekh KR. Ferret Lung Transplantation Models Differential Lymphoid Aggregate Morphology Between Restrictive and Obstructive Forms of Chronic Lung Allograft Dysfunction. Transplantation. PMID 35442232 DOI: 10.1097/TP.0000000000004148  0.185
2021 An D, Li K, Rowe DK, Diaz MCH, Griffin EF, Beavis AC, Johnson SK, Padykula I, Jones CA, Briggs K, Li G, Lin Y, Huang J, Mousa J, Brindley M, ... ... Meyerholz DK, et al. Protection of K18-hACE2 mice and ferrets against SARS-CoV-2 challenge by a single-dose mucosal immunization with a parainfluenza virus 5-based COVID-19 vaccine. Science Advances. 7. PMID 34215591 DOI: 10.1126/sciadv.abi5246  0.18
2023 Lei L, Traore S, Romano Ibarra GS, Karp PH, Rehman T, Meyerholz DK, Zabner J, Stoltz DA, Sinn PL, Welsh MJ, McCray PB, Thornell IM. CFTR-rich ionocytes mediate chloride absorption across airway epithelia. The Journal of Clinical Investigation. PMID 37581935 DOI: 10.1172/JCI171268  0.179
2020 Zheng J, Wang Y, Li K, Meyerholz DK, Allamargot C, Perlman S. SARS-CoV-2-induced immune activation and death of monocyte-derived human macrophages and dendritic cells. The Journal of Infectious Diseases. PMID 33277988 DOI: 10.1093/infdis/jiaa753  0.179
2023 Mazgaeen L, Yorek M, Saini S, Vogel P, Meyerholz DK, Kanneganti TD, Gurung P. CD47 halts -deficient neutrophils from provoking lethal inflammation. Science Advances. 9: eade3942. PMID 36608128 DOI: 10.1126/sciadv.ade3942  0.178
2023 Pan R, Meyerholz DK, Perlman S. Cells that survive acute murine SARS-CoV-2 infection are detected nearly exclusively in the respiratory tract. The Journal of Clinical Investigation. 133. PMID 37966119 DOI: 10.1172/JCI172659  0.177
2012 Capparella A, Loew S, Meyerholz DK. Ecology: Bat deaths from wind turbine blades. Nature. 488: 32. PMID 22859192 DOI: 10.1038/488032D  0.174
2022 Adissu HA, Meyerholz DK, Martinot AJ, Ward JM. Special focus on SARS-CoV-2 and other zoonotic respiratory coronaviruses in animal models. Veterinary Pathology. 59: 513-515. PMID 35713355 DOI: 10.1177/03009858221096502  0.171
2023 Gress AR, Ronayne CE, Thiede JM, Meyerholz DK, Okurut S, Stumpf J, Mathes TV, Ssebambulidde K, Meya DB, Cresswell FV, Boulware DR, Bold TD. Recently activated CD4 T cells in tuberculosis express OX40 as a target for host-directed immunotherapy. Nature Communications. 14: 8423. PMID 38110410 DOI: 10.1038/s41467-023-44152-8  0.169
2013 Loew SS, Rollins KE, Meyerholz DK, Capparella AP. Re-evaluation of collision risk at wind farms Biological Conservation. 157: 432. DOI: 10.1016/J.Biocon.2012.07.007  0.169
2021 Maharjan CK, Umesalma S, Kaemmer CA, Muniz VP, Bauchle C, Mott SL, Zamba KD, Breheny P, Leidinger MR, Darbro BW, Stephens SB, Meyerholz DK, Quelle DE. RABL6A Promotes Pancreatic Neuroendocrine Tumor Angiogenesis and Progression In Vivo. Biomedicines. 9. PMID 34199469 DOI: 10.3390/biomedicines9060633  0.169
2021 Maharjan CK, Umesalma S, Kaemmer CA, Muniz VP, Bauchle C, Mott SL, Zamba KD, Breheny P, Leidinger MR, Darbro BW, Stephens SB, Meyerholz DK, Quelle DE. RABL6A Promotes Pancreatic Neuroendocrine Tumor Angiogenesis and Progression In Vivo Biomedicines. 9: 633. DOI: 10.3390/biomedicines9060633  0.169
2024 Meyerholz DK, Burrough ER, Kirchhof N, Anderson DJ, Helke KL. Swine models in translational research and medicine. Veterinary Pathology. 3009858231222235. PMID 38197394 DOI: 10.1177/03009858231222235  0.168
2022 Meyerholz DK. Rigid respiration: fulminant pulmonary fibrosis after COVID-19. Ebiomedicine. 87: 104428. PMID 36580850 DOI: 10.1016/j.ebiom.2022.104428  0.167
2022 Verma AK, Zheng J, Meyerholz DK, Perlman S. SARS-CoV-2 infection of sustentacular cells disrupts olfactory signaling pathways. Jci Insight. PMID 36378534 DOI: 10.1172/jci.insight.160277  0.166
2020 Areecheewakul S, Adamcakova-Dodd A, Givens BE, Steines BR, Wang Y, Meyerholz DK, Parizek NJ, Altmaier R, Haque E, O'Shaughnessy PT, Salem AK, Thorne PS. Toxicity assessment of metal oxide nanomaterials using screening and murine acute inhalation studies. Nanoimpact. 18. PMID 32968700 DOI: 10.1016/j.impact.2020.100214  0.159
2021 Helke KL, Meyerholz DK, Beck AP, Burrough ER, Derscheid RJ, Löhr C, McInnes EF, Scudamore CL, Brayton CF. Research Relevant Background Lesions and Conditions: Ferrets, Dogs, Swine, Sheep, and Goats. Ilar Journal. PMID 33712827 DOI: 10.1093/ilar/ilab005  0.155
2022 Cooper TK, Meyerholz DK, Beck AP, Delaney MA, Piersigilli A, Southard TL, Brayton CF. Research-Relevant Conditions and Pathology of Laboratory Mice, Rats, Gerbils, Guinea Pigs, Hamsters, Naked Mole Rats, and Rabbits. Ilar Journal. PMID 34979559 DOI: 10.1093/ilar/ilab022  0.154
2023 Li P, Xue B, Schnicker NJ, Wong LR, Meyerholz DK, Perlman S. Nsp3-N interactions are critical for SARS-CoV-2 fitness and virulence. Proceedings of the National Academy of Sciences of the United States of America. 120: e2305674120. PMID 37487098 DOI: 10.1073/pnas.2305674120  0.144
2022 Meyerholz DK, Leidinger MR, Goeken JA, Businga TR, Akers A, Vizuett S, Kaemmer CA, Kohlmeyer JL, Dodd RD, Quelle DE. Utility of CD138/syndecan-1 immunohistochemistry for localization of plasmacytes is tissue-dependent in B6 mice. Bmc Research Notes. 15: 219. PMID 35752869 DOI: 10.1186/s13104-022-06100-5  0.143
2024 Gabriel V, Zdyrski C, Sahoo DK, Ralston A, Wickham H, Bourgois-Mochel A, Ahmed B, Merodio MM, Paukner K, Piñeyro P, Kopper J, Rowe EW, Smith JD, Meyerholz D, Kol A, et al. Adult Animal Stem Cell-Derived Organoids in Biomedical Research and the One Health Paradigm. International Journal of Molecular Sciences. 25. PMID 38255775 DOI: 10.3390/ijms25020701  0.142
2021 Fiege JK, Block KE, Pierson MJ, Nanda H, Shepherd FK, Mickelson CK, Stolley JM, Matchett WE, Wijeyesinghe S, Meyerholz DK, Vezys V, Shen SS, Hamilton SE, Masopust D, Langlois RA. Mice with diverse microbial exposure histories as a model for preclinical vaccine testing. Cell Host & Microbe. PMID 34731647 DOI: 10.1016/j.chom.2021.10.001  0.142
2023 Díaz-Regañón D, Gabriel V, Livania V, Liu D, Ahmed BH, Lincoln A, Wickham H, Ralston A, Merodio MM, Sahoo DK, Zdyrski C, Meyerholz DK, Mochel JP, Allenspach K. Changes of Enterocyte Morphology and Enterocyte: Goblet Cell Ratios in Dogs with Protein-Losing and Non-Protein-Losing Chronic Enteropathies. Veterinary Sciences. 10. PMID 37505823 DOI: 10.3390/vetsci10070417  0.141
2023 Areecheewakul S, Adamcakova-Dodd A, Zacharias ZR, Jing X, Meyerholz DK, Legge KL, Houtman JCD, O'Shaughnessy PT, Thorne PS, Salem AK. Immunomodulatory Effects of Subacute Inhalation Exposure to Copper Oxide Nanoparticles in House Dust Mite-Induced Asthma. Acs Nano. PMID 37463491 DOI: 10.1021/acsnano.3c01668  0.14
2021 Hoenerhoff MJ, Meyerholz DK, Brayton C, Beck AP. Challenges and Opportunities for the Veterinary Pathologist in Biomedical Research. Veterinary Pathology. 58: 258-265. PMID 33327888 DOI: 10.1177/0300985820974005  0.135
2022 Areecheewakul S, Adamcakova-Dodd A, Haque E, Jing X, Meyerholz DK, O'Shaughnessy PT, Thorne PS, Salem AK. Time course of pulmonary inflammation and trace element biodistribution during and after sub-acute inhalation exposure to copper oxide nanoparticles in a murine model. Particle and Fibre Toxicology. 19: 40. PMID 35698146 DOI: 10.1186/s12989-022-00480-z  0.134
2022 Kohlmeyer JL, Kaemmer CA, Lingo JJ, Voigt E, Leidinger MR, McGivney GR, Scherer A, Koppenhafer SL, Gordon DJ, Breheny P, Meyerholz DK, Tanas MR, Dodd RD, Quelle DE. Oncogenic RABL6A promotes NF1-associated MPNST progression in vivo. Neuro-Oncology Advances. 4: vdac047. PMID 35571990 DOI: 10.1093/noajnl/vdac047  0.122
2023 Teghanemt A, Misel-Wuchter K, Heath J, Thurman A, Pulipati P, Dixit G, Geesala R, Meyerholz DK, Maretzky T, Pezzulo A, Issuree PD. DNA demethylation fine-tunes IL-2 production during thymic regulatory T cell differentiation. Embo Reports. e55543. PMID 36880575 DOI: 10.15252/embr.202255543  0.122
2024 Zdyrski C, Gabriel V, Gessler TB, Ralston A, Sifuentes-Romero I, Kundu D, Honold S, Wickham H, Topping NE, Sahoo DK, Bista B, Tamplin J, Ospina O, Piñeyro P, Arriaga M, ... ... Meyerholz DK, et al. Establishment and characterization of turtle liver organoids provides a potential model to decode their unique adaptations. Communications Biology. 7: 218. PMID 38388772 DOI: 10.1038/s42003-024-05818-1  0.12
2013 Samuel I, Williard D, Twait E, Meyerholz D, Yuan Z. The novel cytokine IL-33 activates acinar cell inflammatory pathways and induces acute pancreatic inflammation Pancreatology. 13: e70. DOI: 10.1016/J.PAN.2012.12.300  0.12
2024 Gabriel V, Lincoln A, Zdyrski C, Ralston A, Wickham H, Honold S, Ahmed BH, Paukner K, Feauto R, Merodio MM, Piñeyro P, Meyerholz D, Allenspach K, Mochel JP. Evaluation of different media compositions promoting hepatocyte differentiation in the canine liver organoid model. Heliyon. 10: e28420. PMID 38590903 DOI: 10.1016/j.heliyon.2024.e28420  0.12
2024 Tan TJC, Verma AK, Odle A, Lei R, Meyerholz DK, Matreyek KA, Perlman S, Wong LR, Wu NC. Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike. Proceedings of the National Academy of Sciences of the United States of America. 121: e2317222121. PMID 38557175 DOI: 10.1073/pnas.2317222121  0.12
2022 Larson T, Khandelwal V, Weber MA, Leidinger MR, Meyerholz DK, Narayanan NS, Zhang Q. Mice expressing P301S mutant human tau have deficits in interval timing. Behavioural Brain Research. 432: 113967. PMID 35718229 DOI: 10.1016/j.bbr.2022.113967  0.112
2022 Li Y, Talbot CL, Chandravanshi B, Ksiazek A, Sood A, Chowdhury KH, Maschek JA, Cox J, Babu AKS, Paz HA, Babu PVA, Meyerholz DK, Wankhade UD, Holland W, Shyong Tai E, et al. Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis. Scientific Reports. 12: 7273. PMID 35508667 DOI: 10.1038/s41598-022-11219-3  0.102
2010 O'Keefe BR, Giomarelli B, Barnard DL, Shenoy SR, Chan PKS, McMahon JB, Palmer KE, Barnett BW, Meyerholz DK, Wohlford-Lenane CL, McCray PB. Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae (Journal of Virology (2010) 84, 5 (2511-2010)) Journal of Virology. 84: 5456. DOI: 10.1128/JVI.00537-10  0.087
2022 Lesnak JB, Nakhla DS, Plumb AN, McMillan A, Saha S, Gupta N, Xu Y, Phruttiwanichakun P, Rasmussen L, Meyerholz DK, Salem AK, Sluka KA. Selective androgen receptor modulator microparticle formulation reverses muscle hyperalgesia in a mouse model of widespread muscle pain. Pain. PMID 36508167 DOI: 10.1097/j.pain.0000000000002841  0.085
2021 Meyerholz DK, Adissu HA, Carvalho T, Atkins HM, Rissi DR, Beck AP, Ward JM, Piersigilli A. Exclusion of Expert Contributors From Authorship Limits the Quality of Scientific Articles. Veterinary Pathology. 3009858211011943. PMID 33906549 DOI: 10.1177/03009858211011943  0.084
2020 Acri T, Laird NZ, Jaidev LR, Meyerholz DK, Salem AK, Shin K. Non-viral gene delivery embedded in biomimetically mineralized matrices for bone tissue engineering. Tissue Engineering. Part A. PMID 33086991 DOI: 10.1089/ten.TEA.2020.0206  0.075
2023 Kohlmeyer JL, Lingo JJ, Kaemmer CA, Scherer A, Warrier A, Voigt E, Raygoza Garay JA, McGivney GR, Brockman QR, Tang A, Calizo A, Pollard K, Zhang X, Hirbe AC, Pratilas CA, ... ... Meyerholz DK, et al. CDK4/6-MEK inhibition in MPNSTs causes plasma cell infiltration, sensitization to PD-L1 blockade, and tumor regression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 37410426 DOI: 10.1158/1078-0432.CCR-23-0749  0.058
2023 McInnes EF, Meyerholz DK, Arends MJ. Concerns about pathology expertise and data quality. The Journal of Pathology. PMID 36715663 DOI: 10.1002/path.6058  0.025
2023 Meyerholz DK. Commotio Cordis and One Medicine. Veterinary Pathology. 3009858231162223. PMID 36951122 DOI: 10.1177/03009858231162223  0.021
2018 Sihvo H, Airas N, Simola O, Meyerholz D. Repeatability of Myodegeneration Scoring in Broiler Wooden Breast Myopathy Journal of Comparative Pathology. 158: 147. DOI: 10.1016/j.jcpa.2017.10.166  0.01
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