Kendall J. Blumer, Ph.D. - Publications

Affiliations: 
Cell Biology and Physiology Washington University School of Medicine, St. Louis, MO, United States 
Area:
G protein signaling, RGS proteins

11/103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Oh J, Matkovich SJ, Riek AE, Bindom SM, Shao JS, Head RD, Barve RA, Sands MS, Carmeliet G, Osei-Owusu P, Knutsen RH, Zhang H, Blumer KJ, Nichols CG, Mecham RP, et al. Macrophage secretion of miR-106b-5p causes renin-dependent hypertension. Nature Communications. 11: 4798. PMID 32968066 DOI: 10.1038/s41467-020-18538-x  1
2017 Kanai SM, Edwards AJ, Rurik JG, Osei-Owusu P, Blumer KJ. Proteolytic degradation of Regulator of G Protein Signaling 2 facilitates temporal regulation of Gq/11 signaling and vascular contraction. The Journal of Biological Chemistry. PMID 28974581 DOI: 10.1074/jbc.M117.797134  1
2015 Beeman SC, Osei-Owusu P, Duan C, Engelbach J, Bretthorst GL, Ackerman JJH, Blumer KJ, Garbow JR. Renal DCE-MRI Model Selection Using Bayesian Probability Theory. Tomography (Ann Arbor, Mich.). 1: 61-68. PMID 30042955 DOI: 10.18383/j.tom.2015.00133  1
2015 Osei-Owusu P, Owens EA, Jie L, Reis JS, Forrester SJ, Kawai T, Eguchi S, Singh H, Blumer KJ. Regulation of Renal Hemodynamics and Function by RGS2. Plos One. 10: e0132594. PMID 26193676 DOI: 10.1371/journal.pone.0132594  1
2015 Osei-Owusu P, Blumer KJ. Regulator of G Protein Signaling 2: A Versatile Regulator of Vascular Function. Progress in Molecular Biology and Translational Science. 133: 77-92. PMID 26123303 DOI: 10.1016/bs.pmbts.2015.02.001  1
2015 Osei-Owusu P, Blumer KJ. Regulator of G Protein Signaling 2: A Versatile Regulator of Vascular Function Progress in Molecular Biology and Translational Science. 133: 77-92. DOI: 10.1016/bs.pmbts.2015.02.001  1
2014 Oladipupo SS, Smith C, Santeford A, Park C, Sene A, Wiley LA, Osei-Owusu P, Hsu J, Zapata N, Liu F, Nakamura R, Lavine KJ, Blumer KJ, Choi K, Apte RS, et al. Endothelial cell FGF signaling is required for injury response but not for vascular homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 111: 13379-84. PMID 25139991 DOI: 10.1073/pnas.1324235111  1
2014 Osei-Owusu P, Knutsen RH, Kozel BA, Dietrich HH, Blumer KJ, Mecham RP. Altered reactivity of resistance vasculature contributes to hypertension in elastin insufficiency. American Journal of Physiology. Heart and Circulatory Physiology. 306: H654-66. PMID 24414067 DOI: 10.1152/ajpheart.00601.2013  1
2013 Li A, Knutsen RH, Zhang H, Osei-Owusu P, Moreno-Dominguez A, Harter TM, Uchida K, Remedi MS, Dietrich HH, Bernal-Mizrachi C, Blumer KJ, Mecham RP, Koster JC, Nichols CG. Hypotension due to Kir6.1 gain-of-function in vascular smooth muscle. Journal of the American Heart Association. 2: e000365. PMID 23974906 DOI: 10.1161/JAHA.113.000365  1
2012 Osei-Owusu P, Sabharwal R, Kaltenbronn KM, Rhee MH, Chapleau MW, Dietrich HH, Blumer KJ. Regulator of G protein signaling 2 deficiency causes endothelial dysfunction and impaired endothelium-derived hyperpolarizing factor-mediated relaxation by dysregulating Gi/o signaling. The Journal of Biological Chemistry. 287: 12541-9. PMID 22354966 DOI: 10.1074/jbc.M111.332130  1
2007 Osei-Owusu P, Sun X, Drenan RM, Steinberg TH, Blumer KJ. Regulation of RGS2 and second messenger signaling in vascular smooth muscle cells by cGMP-dependent protein kinase. The Journal of Biological Chemistry. 282: 31656-65. PMID 17681944 DOI: 10.1074/jbc.M706360200  1
Low-probability matches
2018 Onken MD, Makepeace CM, Kaltenbronn KM, Kanai SM, Todd TD, Wang S, Broekelmann TJ, Rao PK, Cooper JA, Blumer KJ. Targeting nucleotide exchange to inhibit constitutively active G protein α subunits in cancer cells. Science Signaling. 11. PMID 30181242 DOI: 10.1126/scisignal.aao6852  0.28
2017 Scherer SL, Cain MD, Kanai SM, Kaltenbronn KM, Blumer KJ. Regulation of neurite morphogenesis by interaction between R7 regulator of G protein signaling complexes and G protein subunit Gα13. The Journal of Biological Chemistry. PMID 28432124 DOI: 10.1074/jbc.M116.771923  0.28
2014 Jia L, Chisari M, Maktabi MH, Sobieski C, Zhou H, Konopko AM, Martin BR, Mennerick SJ, Blumer KJ. A mechanism regulating G protein-coupled receptor signaling that requires cycles of protein palmitoylation and depalmitoylation. The Journal of Biological Chemistry. 289: 6249-57. PMID 24385443 DOI: 10.1074/jbc.M113.531475  0.24
2013 Cain MD, Vo BQ, Kolesnikov AV, Kefalov VJ, Culican SM, Kerschensteiner D, Blumer KJ. An allosteric regulator of R7-RGS proteins influences light-evoked activity and glutamatergic waves in the inner retina. Plos One. 8: e82276. PMID 24349243 DOI: 10.1371/journal.pone.0082276  0.24
2012 Blumer KJ, Weilbaecher K, Piwnica-Worms D. Bioluminescence imaging of prenylation inhibition - Response Clinical Cancer Research. 18: 6078. DOI: 10.1158/1078-0432.CCR-12-2737  0.24
2011 Jia L, Linder ME, Blumer KJ. Gi/o signaling and the palmitoyltransferase DHHC2 regulate palmitate cycling and shuttling of RGS7 family-binding protein. The Journal of Biological Chemistry. 286: 13695-703. PMID 21343290 DOI: 10.1074/jbc.M110.193763  0.24
2010 Dietrich HH, Abendschein DR, Moon SH, Nayeb-Hashemi N, Mancuso DJ, Jenkins CM, Kaltenbronn KM, Blumer KJ, Turk J, Gross RW. Genetic ablation of calcium-independent phospholipase A(2)beta causes hypercontractility and markedly attenuates endothelium-dependent relaxation to acetylcholine. American Journal of Physiology. Heart and Circulatory Physiology. 298: H2208-20. PMID 20382858 DOI: 10.1152/ajpheart.00839.2009  0.24
2009 Inoue-Mochita M, Inoue T, Epstein DL, Blumer KJ, Rao PV. RGS2-deficient mice exhibit decreased intraocular pressure and increased retinal ganglion cell survival. Molecular Vision. 15: 495-504. PMID 19262744  0.24
2009 Jayaraman M, Zhou H, Jia L, Cain MD, Blumer KJ. R9AP and R7BP: traffic cops for the RGS7 family in phototransduction and neuronal GPCR signaling. Trends in Pharmacological Sciences. 30: 17-24. PMID 19042037 DOI: 10.1016/j.tips.2008.10.002  0.24
2008 Gu S, Anton A, Salim S, Blumer KJ, Dessauer CW, Heximer SP. Alternative translation initiation of human regulators of G-protein signaling-2 yields a set of functionally distinct proteins. Molecular Pharmacology. 73: 1-11. PMID 17901199 DOI: 10.1124/mol.107.036285  0.24
2007 Blumer KJ, Thorner J. An adrenaline (and gold?) rush for the GPCR community. Acs Chemical Biology. 2: 783-6. PMID 18154265 DOI: 10.1021/cb7002412  0.24
2007 Tank J, Obst M, Diedrich A, Brychta RJ, Blumer KJ, Heusser K, Jordan J, Luft FC, Gross V. Sympathetic nerve traffic and circulating norepinephrine levels in RGS2-deficient mice. Autonomic Neuroscience : Basic & Clinical. 136: 52-7. PMID 17507294 DOI: 10.1016/j.autneu.2007.04.001  0.24
2007 Heximer SP, Blumer KJ. RGS proteins: Swiss army knives in seven-transmembrane domain receptor signaling networks. Science's Stke : Signal Transduction Knowledge Environment. 2007: pe2. PMID 17244887 DOI: 10.1126/stke.3702007pe2  0.24
2006 Kim K, Galletta BJ, Schmidt KO, Chang FS, Blumer KJ, Cooper JA. Actin-based motility during endocytosis in budding yeast. Molecular Biology of the Cell. 17: 1354-63. PMID 16394096 DOI: 10.1091/mbc.E05-10-0925  0.24
2006 Obst M, Tank J, Plehm R, Blumer KJ, Diedrich A, Jordan J, Luft FC, Gross V. NO-dependent blood pressure regulation in RGS2-deficient mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 290: R1012-9. PMID 16269576 DOI: 10.1152/ajpregu.00288.2005  0.24
2005 Overton MC, Chinault SL, Blumer KJ. Oligomerization of G-protein-coupled receptors: lessons from the yeast Saccharomyces cerevisiae. Eukaryotic Cell. 4: 1963-70. PMID 16339714 DOI: 10.1128/EC.4.12.1963-1970.2005  0.24
2005 Chang FS, Han GS, Carman GM, Blumer KJ. A WASp-binding type II phosphatidylinositol 4-kinase required for actin polymerization-driven endosome motility. The Journal of Cell Biology. 171: 133-42. PMID 16216926 DOI: 10.1083/jcb.200501086  0.24
2005 Gross V, Tank J, Obst M, Plehm R, Blumer KJ, Diedrich A, Jordan J, Luft FC. Autonomic nervous system and blood pressure regulation in RGS2-deficient mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 288: R1134-42. PMID 15661972 DOI: 10.1152/ajpregu.00246.2004  0.24
2004 Harris IS, Treskov I, Rowley MW, Heximer S, Kaltenbronn K, Finck BN, Gross RW, Kelly DP, Blumer KJ, Muslin AJ. G-protein signaling participates in the development of diabetic cardiomyopathy. Diabetes. 53: 3082-90. PMID 15561937 DOI: 10.2337/diabetes.53.12.3082  0.24
2004 Larminie C, Murdock P, Walhin JP, Duckworth M, Blumer KJ, Scheideler MA, Garnier M. Selective expression of regulators of G-protein signaling (RGS) in the human central nervous system. Brain Research. Molecular Brain Research. 122: 24-34. PMID 14992813 DOI: 10.1016/j.molbrainres.2003.11.014  0.24
2004 Wild AC, Yu JW, Lemmon MA, Blumer KJ. The p21-activated protein kinase-related kinase Cla4 is a coincidence detector of signaling by Cdc42 and phosphatidylinositol 4-phosphate. The Journal of Biological Chemistry. 279: 17101-10. PMID 14766750 DOI: 10.1074/jbc.M314035200  0.24
2004 Chinault SL, Overton MC, Blumer KJ. Subunits of a yeast oligomeric G protein-coupled receptor are activated independently by agonist but function in concert to activate G protein heterotrimers. The Journal of Biological Chemistry. 279: 16091-100. PMID 14764600 DOI: 10.1074/jbc.M311099200  0.24
2004 Blumer KJ. Vision: the need for speed. Nature. 427: 20-1. PMID 14702067 DOI: 10.1038/427020a  0.24
2003 Blumer KJ, Cooper JA. Go ahead, break my symmetry! Nature Cell Biology. 5: 1048-9. PMID 14647302 DOI: 10.1038/ncb1203-1048  0.24
2003 Faury G, Pezet M, Knutsen RH, Boyle WA, Heximer SP, McLean SE, Minkes RK, Blumer KJ, Kovacs A, Kelly DP, Li DY, Starcher B, Mecham RP. Developmental adaptation of the mouse cardiovascular system to elastin haploinsufficiency. The Journal of Clinical Investigation. 112: 1419-28. PMID 14597767 DOI: 10.1172/JCI19028  0.24
2003 Overton MC, Chinault SL, Blumer KJ. Oligomerization, biogenesis, and signaling is promoted by a glycophorin A-like dimerization motif in transmembrane domain 1 of a yeast G protein-coupled receptor. The Journal of Biological Chemistry. 278: 49369-77. PMID 14506226 DOI: 10.1074/jbc.M308654200  0.24
2003 Floyd DH, Geva A, Bruinsma SP, Overton MC, Blumer KJ, Baranski TJ. C5a receptor oligomerization. II. Fluorescence resonance energy transfer studies of a human G protein-coupled receptor expressed in yeast. The Journal of Biological Chemistry. 278: 35354-61. PMID 12835318 DOI: 10.1074/jbc.M305607200  0.24
2003 Heximer SP, Knutsen RH, Sun X, Kaltenbronn KM, Rhee MH, Peng N, Oliveira-dos-Santos A, Penninger JM, Muslin AJ, Steinberg TH, Wyss JM, Mecham RP, Blumer KJ. Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice. The Journal of Clinical Investigation. 111: 1259. PMID 12697745  0.24
2003 Chinault SL, Blumer KJ. The C-terminal tail preceding the CAAX box of a yeast G protein gamma subunit is dispensable for receptor-mediated G protein activation in vivo. The Journal of Biological Chemistry. 278: 20638-44. PMID 12665529 DOI: 10.1074/jbc.M212701200  0.24
2003 Chang FS, Stefan CJ, Blumer KJ. A WASp homolog powers actin polymerization-dependent motility of endosomes in vivo. Current Biology : Cb. 13: 455-63. PMID 12646127 DOI: 10.1016/S0960-9822(03)00131-3  0.24
2003 Heximer SP, Knutsen RH, Sun X, Kaltenbronn KM, Rhee MH, Peng N, Oliveira-dos-Santos A, Penninger JM, Muslin AJ, Steinberg TH, Wyss JM, Mecham RP, Blumer KJ. Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice. The Journal of Clinical Investigation. 111: 445-52. PMID 12588882 DOI: 10.1172/JCI15598  0.24
2002 Overton MC, Blumer KJ. Use of fluorescence resonance energy transfer to analyze oligomerization of G-protein-coupled receptors expressed in yeast. Methods (San Diego, Calif.). 27: 324-32. PMID 12217648 DOI: 10.1016/S1046-2023(02)00090-7  0.24
2002 Overton MC, Blumer KJ. The extracellular N-terminal domain and transmembrane domains 1 and 2 mediate oligomerization of a yeast G protein-coupled receptor. The Journal of Biological Chemistry. 277: 41463-72. PMID 12194975 DOI: 10.1074/jbc.M205368200  0.24
2001 Heximer SP, Lim H, Bernard JL, Blumer KJ. Mechanisms governing subcellular localization and function of human RGS2. The Journal of Biological Chemistry. 276: 14195-203. PMID 11278586 DOI: 10.1074/jbc.M009942200  0.24
2001 Rogers JH, Tsirka A, Kovacs A, Blumer KJ, Dorn GW, Muslin AJ. RGS4 reduces contractile dysfunction and hypertrophic gene induction in Galpha q overexpressing mice. Journal of Molecular and Cellular Cardiology. 33: 209-18. PMID 11162127 DOI: 10.1006/jmcc.2000.1307  0.24
2000 Wu C, Zeng Q, Blumer KJ, Muslin AJ. RGS proteins inhibit Xwnt-8 signaling in Xenopus embryonic development. Development (Cambridge, England). 127: 2773-84. PMID 10851124  0.24
2000 Overton MC, Blumer KJ. G-protein-coupled receptors function as oligomers in vivo. Current Biology : Cb. 10: 341-4. PMID 10744981 DOI: 10.1016/S0960-9822(00)00386-9  0.24
2000 Manahan CL, Patnana M, Blumer KJ, Linder ME. Dual lipid modification motifs in G(alpha) and G(gamma) subunits are required for full activity of the pheromone response pathway in Saccharomyces cerevisiae. Molecular Biology of the Cell. 11: 957-68. PMID 10712512 DOI: 10.1091/mbc.11.3.957  0.24
1999 Heximer SP, Srinivasa SP, Bernstein LS, Bernard JL, Linder ME, Hepler JR, Blumer KJ. G protein selectivity is a determinant of RGS2 function. The Journal of Biological Chemistry. 274: 34253-9. PMID 10567399 DOI: 10.1074/jbc.274.48.34253  0.24
1999 Holly SP, Blumer KJ. PAK-family kinases regulate cell and actin polarization throughout the cell cycle of Saccharomyces cerevisiae. The Journal of Cell Biology. 147: 845-56. PMID 10562285 DOI: 10.1083/jcb.147.4.845  0.24
1999 Takesono A, Zahner J, Blumer KJ, Nagao T, Kurose H. Negative regulation of alpha2-adrenergic receptor-mediated Gi signalling by a novel pathway. The Biochemical Journal. 343: 77-85. PMID 10493914 DOI: 10.1042/0264-6021:3430077  0.24
1999 Rogers JH, Tamirisa P, Kovacs A, Weinheimer C, Courtois M, Blumer KJ, Kelly DP, Muslin AJ. RGS4 causes increased mortality and reduced cardiac hypertrophy in response to pressure overload. The Journal of Clinical Investigation. 104: 567-76. PMID 10487771 DOI: 10.1172/JCI6713  0.24
1999 Tamirisa P, Blumer KJ, Muslin AJ. RGS4 inhibits G-protein signaling in cardiomyocytes. Circulation. 99: 441-7. PMID 9918533  0.24
1999 Stefan CJ, Blumer KJ. A syntaxin homolog encoded by VAM3 mediates down-regulation of a yeast G protein-coupled receptor. The Journal of Biological Chemistry. 274: 1835-41. PMID 9880567 DOI: 10.1074/jbc.274.3.1835  0.24
1998 Eby JJ, Holly SP, van Drogen F, Grishin AV, Peter M, Drubin DG, Blumer KJ. Actin cytoskeleton organization regulated by the PAK family of protein kinases. Current Biology : Cb. 8: 967-70. PMID 9742399  0.24
1998 Druey KM, Sullivan BM, Brown D, Fischer ER, Watson N, Blumer KJ, Gerfen CR, Scheschonka A, Kehrl JH. Expression of GTPase-deficient Gialpha2 results in translocation of cytoplasmic RGS4 to the plasma membrane. The Journal of Biological Chemistry. 273: 18405-10. PMID 9660808 DOI: 10.1074/jbc.273.29.18405  0.24
1998 Grishin AV, Rothenberg M, Downs MA, Blumer KJ. Mot3, a Zn finger transcription factor that modulates gene expression and attenuates mating pheromone signaling in Saccharomyces cerevisiae. Genetics. 149: 879-92. PMID 9611199  0.24
1998 Srinivasa SP, Bernstein LS, Blumer KJ, Linder ME. Plasma membrane localization is required for RGS4 function in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 95: 5584-9. PMID 9576926 DOI: 10.1073/pnas.95.10.5584  0.24
1998 Stefan CJ, Overton MC, Blumer KJ. Mechanisms governing the activation and trafficking of yeast G protein-coupled receptors. Molecular Biology of the Cell. 9: 885-99. PMID 9529386  0.24
1998 Zhang S, Watson N, Zahner J, Rottman JN, Blumer KJ, Muslin AJ. RGS3 and RGS4 are GTPase activating proteins in the heart. Journal of Molecular and Cellular Cardiology. 30: 269-76. PMID 9515003 DOI: 10.1006/jmcc.1997.0591  0.24
1998 Srinivasa SP, Watson N, Overton MC, Blumer KJ. Mechanism of RGS4, a GTPase-activating protein for G protein alpha subunits. The Journal of Biological Chemistry. 273: 1529-33. PMID 9430692 DOI: 10.1074/jbc.273.3.1529  0.24
1998 Overton MC, Stefan CJ, Blumer KJ. Constitutively active and dominant-negative G protein coupled receptor mutants Faseb Journal. 12: A1465.  0.24
1997 Heximer SP, Watson N, Linder ME, Blumer KJ, Hepler JR. RGS2/G0S8 is a selective inhibitor of Gqalpha function. Proceedings of the National Academy of Sciences of the United States of America. 94: 14389-93. PMID 9405622 DOI: 10.1073/pnas.94.26.14389  0.24
1997 Huang KM, Gullberg L, Nelson KK, Stefan CJ, Blumer K, Lemmon SK. Novel functions of clathrin light chains: Clathrin heavy chain trimerization is defective in light chain-deficient yeast Journal of Cell Science. 110: 899-910. PMID 9133677  0.24
1996 Watson N, Linder ME, Druey KM, Kehrl JH, Blumer KJ. RGS family members: GTPase-activating proteins for heterotrimeric G-protein alpha-subunits. Nature. 383: 172-5. PMID 8774882 DOI: 10.1038/383172a0  0.24
1996 Druey KM, Blumer KJ, Kang VH, Kehrl JH. Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family. Nature. 379: 742-6. PMID 8602223 DOI: 10.1038/379742a0  0.24
1996 Druev KM, Blumer KJ, Kang VH, Kehrl JH. Inhibition of g protein-mediated map kinase activation by members of a novel mammalian gene family Journal of Investigative Medicine. 44: 271a.  0.24
1995 Richard S, Yu D, Blumer KJ, Hausladen D, Olszowy MW, Connelly PA, Shaw AS. Association of p62, a multifunctional SH2- and SH3-domain-binding protein, with src family tyrosine kinases, Grb2, and phospholipase C gamma-1. Molecular and Cellular Biology. 15: 186-97. PMID 7799925  0.24
1994 Blumer KJ, Johnson GL, Lange-Carter CA. Mammalian mitogen-activated protein kinase kinase kinase (MEKK) can function in a yeast mitogen-activated protein kinase pathway downstream of protein kinase C. Proceedings of the National Academy of Sciences of the United States of America. 91: 4925-9. PMID 8197159 DOI: 10.1073/pnas.91.11.4925  0.24
1994 Stefan CJ, Blumer KJ. The third cytoplasmic loop of a yeast G-protein-coupled receptor controls pathway activation, ligand discrimination, and receptor internalization. Molecular and Cellular Biology. 14: 3339-49. PMID 8164685  0.24
1994 Blumer KJ, Johnson GL. Diversity in function and regulation of MAP kinase pathways. Trends in Biochemical Sciences. 19: 236-40. PMID 8073500 DOI: 10.1016/0968-0004(94)90147-3  0.24
1994 Grishin AV, Weiner JL, Blumer KJ. Biochemical and genetic analysis of dominant-negative mutations affecting a yeast G-protein gamma subunit. Molecular and Cellular Biology. 14: 4571-8. PMID 8007961  0.24
1994 Grishin AV, Weiner JL, Blumer KJ. Control of adaptation to mating pheromone by G protein beta subunits of Saccharomyces cerevisiae. Genetics. 138: 1081-92. PMID 7896092  0.24
1993 Lange-Carter CA, Pleiman CM, Gardner AM, Blumer KJ, Johnson GL. A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf. Science (New York, N.Y.). 260: 315-9. PMID 8385802  0.24
1993 Weiner JL, Guttierez-Steil C, Blumer KJ. Disruption of receptor-G protein coupling in yeast promotes the function of an SST2-dependent adaptation pathway. The Journal of Biological Chemistry. 268: 8070-7. PMID 8385135  0.24
1991 Blumer KJ, Thorner J. Receptor-G protein signaling in yeast. Annual Review of Physiology. 53: 37-57. PMID 1904209 DOI: 10.1146/annurev.ph.53.030191.000345  0.24
1990 Kokoska RJ, Blumer KJ, Steege DA. Phage fl mRNA processing in Escherichia coli: search for the upstream products of endonuclease cleavage, requirement for the product of the altered mRNA stability (ams) locus. Biochimie. 72: 803-11. PMID 2085543 DOI: 10.1016/0300-9084(90)90189-N  0.24
1990 Blumer KJ, Thorner J. β and γ subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the α subunit but are required for receptor coupling Proceedings of the National Academy of Sciences of the United States of America. 87: 4363-4367.  0.24
1989 Blumer KJ, Steege DA. Recognition and cleavage signals for mRNA processing lie within local domains of the phage f1 RNA precursors. The Journal of Biological Chemistry. 264: 20770-7. PMID 2684984  0.24
1989 Yu L, Blumer KJ, Davidson N, Lester HA, Thorner J. Functional expression of the yeast alpha-factor receptor in Xenopus oocytes. The Journal of Biological Chemistry. 264: 20847-50. PMID 2556384  0.24
1988 Blumer KJ, Reneke JE, Courchesne WE, Thorner J. Functional domains of a peptide hormone receptor: the alpha-factor receptor (STE2 gene product) of the yeast Saccharomyces cerevisiae. Cold Spring Harbor Symposia On Quantitative Biology. 53: 591-603. PMID 2855497  0.24
1988 Reneke JE, Blumer KJ, Courchesne WE, Thorner J. The carboxy-terminal segment of the yeast alpha-factor receptor is a regulatory domain. Cell. 55: 221-34. PMID 2844413 DOI: 10.1016/0092-8674(88)90045-1  0.24
1988 Blumer KJ, Reneke JE, Thorner J. The STE2 gene product is the ligand-binding component of the alpha-factor receptor of Saccharomyces cerevisiae. The Journal of Biological Chemistry. 263: 10836-42. PMID 2839507  0.24
1987 Blumer KJ, Ivey MR, Steege DA. Translational control of phage f1 gene expression by differential activities of the gene V, VII, IX and VIII initiation sites. Journal of Molecular Biology. 197: 439-51. PMID 3441007 DOI: 10.1016/0022-2836(87)90557-2  0.24
1984 Blumer KJ, Steege DA. mRNA processing in Escherichia coli: an activity encoded by the host processes bacteriophage f1 mRNAs. Nucleic Acids Research. 12: 1847-61. PMID 6322124 DOI: 10.1093/nar/12.4.1847  0.24
2012 Zhou H, Chisari M, Raehal KM, Kaltenbronn KM, Bohn LM, Mennerick SJ, Blumer KJ. GIRK channel modulation by assembly with allosterically regulated RGS proteins. Proceedings of the National Academy of Sciences of the United States of America. 109: 19977-82. PMID 23169654 DOI: 10.1073/pnas.1214337109  0.16
2012 Chinault SL, Prior JL, Kaltenbronn KM, Penly A, Weilbaecher KN, Piwnica-Worms D, Blumer KJ. Breast cancer cell targeting by prenylation inhibitors elucidated in living animals with a bioluminescence reporter. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 4136-44. PMID 22693355 DOI: 10.1158/1078-0432.CCR-12-0642  0.16
2011 Chakir K, Zhu W, Tsang S, Woo AY, Yang D, Wang X, Zeng X, Rhee MH, Mende U, Koitabashi N, Takimoto E, Blumer KJ, Lakatta EG, Kass DA, Xiao RP. RGS2 is a primary terminator of β₂-adrenergic receptor-mediated G(i) signaling. Journal of Molecular and Cellular Cardiology. 50: 1000-7. PMID 21291891 DOI: 10.1016/j.yjmcc.2011.01.015  0.16
2008 Grabowska D, Jayaraman M, Kaltenbronn KM, Sandiford SL, Wang Q, Jenkins S, Slepak VZ, Smith Y, Blumer KJ. Postnatal induction and localization of R7BP, a membrane-anchoring protein for regulator of G protein signaling 7 family-Gbeta5 complexes in brain. Neuroscience. 151: 969-82. PMID 18248908 DOI: 10.1016/j.neuroscience.2007.11.045  0.16
2006 Drenan RM, Doupnik CA, Jayaraman M, Buchwalter AL, Kaltenbronn KM, Huettner JE, Linder ME, Blumer KJ. R7BP augments the function of RGS7*Gbeta5 complexes by a plasma membrane-targeting mechanism. The Journal of Biological Chemistry. 281: 28222-31. PMID 16867977 DOI: 10.1074/jbc.M604428200  0.16
2005 Sun X, Kaltenbronn KM, Steinberg TH, Blumer KJ. RGS2 is a mediator of nitric oxide action on blood pressure and vasoconstrictor signaling. Molecular Pharmacology. 67: 631-9. PMID 15563583 DOI: 10.1124/mol.104.007724  0.16
2003 Tang KM, Wang GR, Lu P, Karas RH, Aronovitz M, Heximer SP, Kaltenbronn KM, Blumer KJ, Siderovski DP, Zhu Y, Mendelsohn ME, Tang M, Wang G. Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure. Nature Medicine. 9: 1506-12. PMID 14608379 DOI: 10.1038/nm958  0.16
2003 Garnier M, Zaratin PF, Ficalora G, Valente M, Fontanella L, Rhee MH, Blumer KJ, Scheideler MA. Up-regulation of regulator of G protein signaling 4 expression in a model of neuropathic pain and insensitivity to morphine. The Journal of Pharmacology and Experimental Therapeutics. 304: 1299-306. PMID 12604710 DOI: 10.1124/jpet.102.043471  0.16
2018 Sun X, Singh S, Blumer K, Bowman GR. Simulation of spontaneous G protein activation reveals a new intermediate driving GDP unbinding. Elife. 7. PMID 30289386 DOI: 10.7554/eLife.38465  0.12
2005 Drenan RM, Doupnik CA, Boyle MP, Muglia LJ, Huettner JE, Linder ME, Blumer KJ. Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family. The Journal of Cell Biology. 169: 623-33. PMID 15897264 DOI: 10.1083/jcb.200502007  0.12
2020 Truong A, Yoo JH, Scherzer M, Sanchez JMS, Dale KJ, Kinsey CG, Richards JR, Shin D, Ghazi P, Onken MD, Blumer KJ, Odelberg SJ, McMahon M. Chloroquine sensitizes GNAQ/11-mutated melanoma to MEK1/2 inhibition. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32933997 DOI: 10.1158/1078-0432.CCR-20-1675  0.01
2018 Singh S, Sun X, Blumer KJ, Bowman GR. Direct Observation of GDP Unbinding Reveals Multiple Allosteric Pathways Underlie G-Protein Activation Biophysical Journal. 114: 398a. DOI: 10.1016/j.bpj.2017.11.2202  0.01
2017 Zayed MA, Wei X, Park KM, Belaygorod L, Naim U, Harvey J, Yin L, Blumer K, Semenkovich CF. N-Acetylcysteine accelerates amputation stump healing in the setting of diabetes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28280002 DOI: 10.1096/fj.201601348R  0.01
2015 Rensing DT, Uppal S, Blumer KJ, Moeller KD. Toward the Selective Inhibition of G Proteins: Total Synthesis of a Simplified YM-254890 Analog. Organic Letters. 17: 2270-3. PMID 25875152 DOI: 10.1021/acs.orglett.5b00944  0.01
2006 Huber TB, Kwoh C, Wu H, Asanuma K, Gödel M, Hartleben B, Blumer KJ, Miner JH, Mundel P, Shaw AS. Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin. The Journal of Clinical Investigation. 116: 1337-45. PMID 16628251 DOI: 10.1172/JCI27400  0.01
2004 Tang M, Wang G, Lu P, Karas RH, Aronovitz M, Heximer SP, Kaltenbronn KM, Blumer KJ, Siderovski DP, Zhu Y, Mendelsohn ME. Erratum: Corrigendum: Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure Nature Medicine. 10: 105-105. DOI: 10.1038/nm0104-105b  0.01
1990 Blumer KJ, Thorner J. Beta and gamma subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the alpha subunit but are required for receptor coupling. Proceedings of the National Academy of Sciences of the United States of America. 87: 4363-7. PMID 2161538  0.01
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