Alexandra Joyner - Publications

Affiliations: 
Memorial Sloan Kettering, Hauppauge, NY, United States 
Area:
Shh signaling, development, genetics

110 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Krishnamurthy A, Lee AS, Bayin NS, Stephen DN, Nasef O, Lao Z, Joyner AL. Engrailed transcription factors direct excitatory cerebellar neuron diversity and survival. Development (Cambridge, England). PMID 38912572 DOI: 10.1242/dev.202502  0.727
2024 Yamada M, Keller RR, Gutierrez RL, Cameron D, Suzuki H, Sanghrajka R, Vaynshteyn J, Gerwin J, Maura F, Hooper W, Shah M, Robine N, Demarest P, Bayin NS, Zapater LJ, ... ... Joyner AL, et al. Childhood cancer mutagenesis caused by transposase-derived PGBD5. Science Advances. 10: eadn4649. PMID 38517960 DOI: 10.1126/sciadv.adn4649  0.678
2023 Krishnamurthy A, Lee AS, Bayin NS, Stephen DN, Nasef O, Lao Z, Joyner AL. Engrailed transcription factors direct excitatory cerebellar neuron diversity and survival. Biorxiv : the Preprint Server For Biology. PMID 38077070 DOI: 10.1101/2023.11.30.569445  0.726
2023 Sanghrajka RM, Koche R, Medrano H, El Nagar S, Stephen DN, Lao Z, Bayin NS, Ge K, Joyner AL. KMT2D suppresses Sonic hedgehog-driven medulloblastoma progression and metastasis. Iscience. 26: 107831. PMID 37822508 DOI: 10.1016/j.isci.2023.107831  0.666
2023 Rallapalli H, Bayin NS, Goldman H, Maric D, Nieman BJ, Koretsky AP, Joyner AL, Turnbull DH. Cell Specificity of Manganese-enhanced MRI Signal in the Cerebellum. Neuroimage. 120198. PMID 37245561 DOI: 10.1016/j.neuroimage.2023.120198  0.679
2022 Lv X, Li S, Li J, Yu XY, Ge X, Li B, Hu S, Lin Y, Zhang S, Yang J, Zhang X, Yan J, Joyner AL, Shi H, Wu Q, et al. Patterned cPCDH expression regulates the fine organization of the neocortex. Nature. 612: 503-511. PMID 36477535 DOI: 10.1038/s41586-022-05495-2  0.314
2022 Joyner AL, Bayin NS. Cerebellum lineage allocation, morphogenesis and repair: impact of interplay amongst cells. Development (Cambridge, England). 149. PMID 36172987 DOI: 10.1242/dev.185587  0.722
2021 Bayin NS, Mizrak D, Stephen DN, Lao Z, Sims PA, Joyner AL. Injury-induced ASCL1 expression orchestrates a transitory cell state required for repair of the neonatal cerebellum. Science Advances. 7: eabj1598. PMID 34878841 DOI: 10.1126/sciadv.abj1598  0.659
2021 Joyner A, Lehmann R, Niswander L. In Memoriam: Kathryn V. Anderson (1952-2020). Developmental Biology. 472: 125-126. PMID 33618188 DOI: 10.1016/j.ydbio.2021.01.001  0.427
2020 Mizrak D, Bayin NS, Yuan J, Liu Z, Suciu RM, Niphakis MJ, Ngo N, Lum KM, Cravatt BF, Joyner AL, Sims PA. Single-Cell Profiling and SCOPE-Seq Reveal Lineage Dynamics of Adult Ventricular-Subventricular Zone Neurogenesis and NOTUM as a Key Regulator. Cell Reports. 31: 107805. PMID 32579931 DOI: 10.1016/J.Celrep.2020.107805  0.703
2020 Ahmadzadeh E, Bayin NS, Qu X, Singh A, Madisen L, Stephen D, Zeng H, Joyner AL, Rosello-Diez A. A collection of genetic mouse lines and related tools for inducible and reversible intersectional misexpression. Development (Cambridge, England). PMID 32366677 DOI: 10.1242/Dev.186650  0.699
2019 Willett RT, Bayin NS, Lee AS, Krishnamurthy A, Wojcinski A, Lao Z, Stephen D, Rosello-Diez A, Dauber-Decker KL, Orvis GD, Wu Z, Tessier-Lavigne M, Joyner AL. Cerebellar nuclei excitatory neurons regulate developmental scaling of presynaptic Purkinje cell number and organ growth. Elife. 8. PMID 31742552 DOI: 10.7554/Elife.50617  0.758
2019 Yang Z, Joyner AL. YAP1 is involved in replenishment of granule cell precursors following injury to the neonatal cerebellum. Developmental Biology. PMID 31376393 DOI: 10.1016/j.ydbio.2019.07.018  0.34
2019 Vladoiu MC, El-Hamamy I, Donovan LK, Farooq H, Holgado BL, Sundaravadanam Y, Ramaswamy V, Hendrikse LD, Kumar S, Mack SC, Lee JJY, Fong V, Juraschka K, Przelicki D, Michealraj A, ... ... Joyner AL, et al. Childhood cerebellar tumours mirror conserved fetal transcriptional programs. Nature. PMID 31043743 DOI: 10.1038/S41586-019-1158-7  0.311
2019 Wojcinski A, Morabito M, Lawton AK, Stephen DN, Joyner AL. Genetic deletion of genes in the cerebellar rhombic lip lineage can stimulate compensation through adaptive reprogramming of ventricular zone-derived progenitors. Neural Development. 14: 4. PMID 30764875 DOI: 10.1186/S13064-019-0128-Y  0.353
2019 Sanghrajka R, Tan I, Wojcinski A, Rallapalli H, Turnbull D, Ge K, Joyner A. TMOD-03. SOMATIC MUTATIONS OF CHROMATIN REGULATOR Kmt2d IN CEREBELLAR PRECURSORS INFLUENCES SHH-MEDULLOBLASTOMA TUMORIGENESIS Neuro-Oncology. 21: vi263-vi263. DOI: 10.1093/Neuonc/Noz175.1102  0.358
2019 El-Hamamy I, Vladoiu M, Donovan L, Farooq H, Holgado B, Ramaswamy V, Cavalli F, Luu B, Chan J, Kleinman C, Joyner A, Jabado N, Stein L, Taylor M. MEDU-40. MATCHING OF SINGLE CELL TRANSCRIPTOMICS FROM CEREBELLAR DEVELOPMENT IDENTIFIES PUTATIVE SUBGROUP SPECIFIC CELLS OF ORIGIN FOR MEDULLOBLASTOMA Neuro-Oncology. 21: ii111-ii112. DOI: 10.1093/Neuonc/Noz036.198  0.409
2018 Bayin NS, Wojcinski A, Mourton A, Saito H, Suzuki N, Joyner AL. Age-dependent dormant resident progenitors are stimulated by injury to regenerate Purkinje neurons. Elife. 7. PMID 30091706 DOI: 10.7554/eLife.39879  0.703
2018 Tan IL, Wojcinski A, Rallapalli H, Lao Z, Sanghrajka RM, Stephen D, Volkova E, Korshunov A, Remke M, Taylor MD, Turnbull DH, Joyner AL. Lateral cerebellum is preferentially sensitive to high sonic hedgehog signaling and medulloblastoma formation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29531057 DOI: 10.1073/pnas.1717815115  0.316
2018 Rodrigo EL, Joyner A. Abstract A20: A mouse model of postnatal Hedgehog-driven muscle tumors shows a common progenitor that relies on loss of Tp53 expression for malignant transformation Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Sarcomas17-A20  0.315
2017 Wojcinski A, Lawton AK, Bayin NS, Lao Z, Stephen DN, Joyner AL. Cerebellar granule cell replenishment postinjury by adaptive reprogramming of Nestin(+) progenitors. Nature Neuroscience. PMID 28805814 DOI: 10.1038/Nn.4621  0.728
2016 Legué E, Gottshall JL, Jaumouillé E, Roselló-Díez A, Shi W, Barraza LH, Washington S, Grant RL, Joyner AL. Differential timing of granule cell production during cerebellum development underlies generation of the foliation pattern. Neural Development. 11: 17. PMID 27609139 DOI: 10.1186/s13064-016-0072-z  0.32
2016 Leffler SR, Legué E, Aristizábal O, Joyner AL, Peskin CS, Turnbull DH. A Mathematical Model of Granule Cell Generation During Mouse Cerebellum Development. Bulletin of Mathematical Biology. PMID 27125657 DOI: 10.1007/S11538-016-0163-3  0.31
2016 Tan I, Wojcinski A, Rallapalli H, Volkova E, Remke M, Korshunov A, Turnbull D, Taylor M, Joyner A. CSIG-10. SHH-MEDULLOBLASTOMA PREFERENTIALLY ARISES FROM GRANULE CELL PRECURSORS IN THE LATERAL CEREBELLUM Neuro-Oncology. 18: vi42-vi42. DOI: 10.1093/Neuonc/Now212.171  0.408
2015 Leto K, Arancillo M, Becker EB, Buffo A, Chiang C, Ding B, Dobyns WB, Dusart I, Haldipur P, Hatten ME, Hoshino M, Joyner AL, Kano M, Kilpatrick DL, Koibuchi N, et al. Consensus Paper: Cerebellar Development. Cerebellum (London, England). PMID 26439486 DOI: 10.1007/S12311-015-0724-2  0.735
2015 Legué E, Riedel E, Joyner AL. Clonal analysis reveals granule cell behaviors and compartmentalization that determine the folded morphology of the cerebellum. Development (Cambridge, England). 142: 1661-71. PMID 25834018 DOI: 10.1242/dev.120287  0.332
2013 Petrova R, Garcia AD, Joyner AL. Titration of GLI3 repressor activity by sonic hedgehog signaling is critical for maintaining multiple adult neural stem cell and astrocyte functions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17490-505. PMID 24174682 DOI: 10.1523/JNEUROSCI.2042-13.2013  0.371
2013 Sgadò P, Genovesi S, Kalinovsky A, Zunino G, Macchi F, Allegra M, Murenu E, Provenzano G, Tripathi PP, Casarosa S, Joyner AL, Bozzi Y. Loss of GABAergic neurons in the hippocampus and cerebral cortex of Engrailed-2 null mutant mice: implications for autism spectrum disorders. Experimental Neurology. 247: 496-505. PMID 23360806 DOI: 10.1016/J.Expneurol.2013.01.021  0.57
2012 Lao Z, Raju GP, Bai CB, Joyner AL. MASTR: a technique for mosaic mutant analysis with spatial and temporal control of recombination using conditional floxed alleles in mice. Cell Reports. 2: 386-96. PMID 22884371 DOI: 10.1016/j.celrep.2012.07.004  0.329
2012 Orvis GD, Hartzell AL, Smith JB, Barraza LH, Wilson SL, Szulc KU, Turnbull DH, Joyner AL. The engrailed homeobox genes are required in multiple cell lineages to coordinate sequential formation of fissures and growth of the cerebellum. Developmental Biology. 367: 25-39. PMID 22564796 DOI: 10.1016/J.Ydbio.2012.04.018  0.373
2011 Sudarov A, Turnbull RK, Kim EJ, Lebel-Potter M, Guillemot F, Joyner AL. Ascl1 genetics reveals insights into cerebellum local circuit assembly. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11055-69. PMID 21795554 DOI: 10.1016/J.Ydbio.2011.05.414  0.614
2011 Blaess S, Bodea GO, Kabanova A, Chanet S, Mugniery E, Derouiche A, Stephen D, Joyner AL. Temporal-spatial changes in Sonic Hedgehog expression and signaling reveal different potentials of ventral mesencephalic progenitors to populate distinct ventral midbrain nuclei. Neural Development. 6: 29. PMID 21689430 DOI: 10.1186/1749-8104-6-29  0.331
2011 Wilson SL, Kalinovsky A, Orvis GD, Joyner AL. Spatially restricted and developmentally dynamic expression of engrailed genes in multiple cerebellar cell types. Cerebellum (London, England). 10: 356-72. PMID 21431469 DOI: 10.1007/S12311-011-0254-5  0.598
2011 Yu X, Nieman BJ, Sudarov A, Szulc KU, Abdollahian DJ, Bhatia N, Lalwani AK, Joyner AL, Turnbull DH. Morphological and functional midbrain phenotypes in Fibroblast Growth Factor 17 mutant mice detected by Mn-enhanced MRI. Neuroimage. 56: 1251-8. PMID 21356319 DOI: 10.1016/J.Neuroimage.2011.02.068  0.388
2011 Legué E, Jaumouillé E, Sultan K, Espinosa S, Barraza L, Joyner A. Cellular compartments and differential cell behaviors underlie formation of the distinct foliation pattern of the mouse cerebellum Developmental Biology. 356: 159. DOI: 10.1016/j.ydbio.2011.05.588  0.385
2010 Seidel K, Ahn CP, Lyons D, Nee A, Ting K, Brownell I, Cao T, Carano RA, Curran T, Schober M, Fuchs E, Joyner A, Martin GR, de Sauvage FJ, Klein OD. Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor. Development (Cambridge, England). 137: 3753-61. PMID 20978073 DOI: 10.1242/Dev.056358  0.613
2010 Garcia AD, Petrova R, Eng L, Joyner AL. Sonic hedgehog regulates discrete populations of astrocytes in the adult mouse forebrain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13597-608. PMID 20943901 DOI: 10.1523/JNEUROSCI.0830-10.2010  0.348
2010 Sillitoe RV, Vogel MW, Joyner AL. Engrailed homeobox genes regulate establishment of the cerebellar afferent circuit map. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 10015-24. PMID 20668186 DOI: 10.1523/Jneurosci.0653-10.2010  0.625
2010 Cheng Y, Sudarov A, Szulc KU, Sgaier SK, Stephen D, Turnbull DH, Joyner AL. The Engrailed homeobox genes determine the different foliation patterns in the vermis and hemispheres of the mammalian cerebellum. Development (Cambridge, England). 137: 519-29. PMID 20081196 DOI: 10.1242/Dev.027045  0.361
2010 Nieman BJ, Shyu JY, Rodriguez JJ, Garcia AD, Joyner AL, Turnbull DH. In vivo MRI of neural cell migration dynamics in the mouse brain. Neuroimage. 50: 456-64. PMID 20053381 DOI: 10.1016/J.Neuroimage.2009.12.107  0.322
2009 Sillitoe RV, Gopal N, Joyner AL. Embryonic origins of ZebrinII parasagittal stripes and establishment of topographic Purkinje cell projections. Neuroscience. 162: 574-88. PMID 19150487 DOI: 10.1016/J.Neuroscience.2008.12.025  0.562
2009 Seidel K, Ahn C, Nee A, Lyons D, Ting K, Brownell I, Peterková R, Lesot H, Schöber M, Joyner A, Sauvage Fd, Klein O. 19-P008 SHH is a master regulator of stem cell-driven continuous growth of the mouse incisor Mechanisms of Development. 126. DOI: 10.1016/J.Mod.2009.06.796  0.339
2009 Legue E, Barraza L, Espinosa S, Luo L, Joyner A. 03-P073 Regional differences in cell behaviors during foliation of the mouse cerebellum Mechanisms of Development. 126: S88. DOI: 10.1016/j.mod.2009.06.126  0.307
2008 Sillitoe RV, Stephen D, Lao Z, Joyner AL. Engrailed homeobox genes determine the organization of Purkinje cell sagittal stripe gene expression in the adult cerebellum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12150-62. PMID 19020009 DOI: 10.1523/Jneurosci.2059-08.2008  0.622
2008 Basson MA, Echevarria D, Ahn CP, Sudarov A, Joyner AL, Mason IJ, Martinez S, Martin GR. Specific regions within the embryonic midbrain and cerebellum require different levels of FGF signaling during development. Development (Cambridge, England). 135: 889-98. PMID 18216176 DOI: 10.1242/dev.011569  0.576
2007 Sgaier SK, Lao Z, Villanueva MP, Berenshteyn F, Stephen D, Turnbull RK, Joyner AL. Genetic subdivision of the tectum and cerebellum into functionally related regions based on differential sensitivity to engrailed proteins. Development (Cambridge, England). 134: 2325-35. PMID 17537797 DOI: 10.1242/dev.000620  0.322
2007 Sillitoe RV, Joyner AL. Morphology, molecular codes, and circuitry produce the three-dimensional complexity of the cerebellum. Annual Review of Cell and Developmental Biology. 23: 549-77. PMID 17506688 DOI: 10.1146/Annurev.Cellbio.23.090506.123237  0.594
2007 Joyner AL, Sillitoe RV, Sgaier S, Cheng Y, Sudarov A. Cerebellum patterning: from folds and stripes to circuits Developmental Biology. 306: 310. DOI: 10.1016/J.Ydbio.2007.03.105  0.52
2006 Atit R, Sgaier SK, Mohamed OA, Taketo MM, Dufort D, Joyner AL, Niswander L, Conlon RA. Beta-catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse. Developmental Biology. 296: 164-76. PMID 16730693 DOI: 10.1016/J.Ydbio.2006.04.449  0.595
2005 Zervas M, Blaess S, Joyner AL. Classical embryological studies and modern genetic analysis of midbrain and cerebellum development. Current Topics in Developmental Biology. 69: 101-38. PMID 16243598 DOI: 10.1016/S0070-2153(05)69005-9  0.314
2005 Kimura H, Stephen D, Joyner A, Curran T. Gli1 is important for medulloblastoma formation in Ptc1+/- mice. Oncogene. 24: 4026-36. PMID 15806168 DOI: 10.1038/Sj.Onc.1208567  0.414
2004 Wadghiri YZ, Blind JA, Duan X, Moreno C, Yu X, Joyner AL, Turnbull DH. Manganese-enhanced magnetic resonance imaging (MEMRI) of mouse brain development. Nmr in Biomedicine. 17: 613-9. PMID 15761950 DOI: 10.1002/Nbm.932  0.373
2004 Corrales JD, Rocco GL, Blaess S, Guo Q, Joyner AL. Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development. Development (Cambridge, England). 131: 5581-90. PMID 15496441 DOI: 10.1242/dev.01438  0.39
2004 Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, et al. The knockout mouse project. Nature Genetics. 36: 921-4. PMID 15340423 DOI: 10.1038/Ng0904-921  0.344
2004 Hopkins KM, Auerbach W, Wang XY, Hande MP, Hang H, Wolgemuth DJ, Joyner AL, Lieberman HB. Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality. Molecular and Cellular Biology. 24: 7235-48. PMID 15282322 DOI: 10.1128/MCB.24.16.7235-7248.2004  0.304
2003 Guo Q, Loomis C, Joyner AL. Fate map of mouse ventral limb ectoderm and the apical ectodermal ridge. Developmental Biology. 264: 166-78. PMID 14623239 DOI: 10.1016/J.Ydbio.2003.08.012  0.35
2003 Liu A, Li JY, Bromleigh C, Lao Z, Niswander LA, Joyner AL. FGF17b and FGF18 have different midbrain regulatory properties from FGF8b or activated FGF receptors. Development (Cambridge, England). 130: 6175-85. PMID 14602678 DOI: 10.1242/dev.00845  0.584
2003 Gong S, Zheng C, Doughty ML, Losos K, Didkovsky N, Schambra UB, Nowak NJ, Joyner A, Leblanc G, Hatten ME, Heintz N. A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature. 425: 917-25. PMID 14586460 DOI: 10.1038/nature02033  0.655
2002 Nakashima M, Tanese N, Ito M, Auerbach W, Bai C, Furukawa T, Toyono T, Akamine A, Joyner AL. A novel gene, GliH1, with homology to the Gli zinc finger domain not required for mouse development. Mechanisms of Development. 119: 21-34. PMID 12385751 DOI: 10.1016/S0925-4773(02)00291-5  0.321
2002 Li JY, Lao Z, Joyner AL. Changing requirements for Gbx2 in development of the cerebellum and maintenance of the mid/hindbrain organizer. Neuron. 36: 31-43. PMID 12367504 DOI: 10.1016/S0896-6273(02)00935-2  0.313
2001 Li JY, Joyner AL. Otx2 and Gbx2 are required for refinement and not induction of mid-hindbrain gene expression. Development (Cambridge, England). 128: 4979-91. PMID 11748135  0.329
2001 Liu A, Joyner AL. EN and GBX2 play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region. Development (Cambridge, England). 128: 181-91. PMID 11124114  0.329
2000 Kimmel RA, Turnbull DH, Blanquet V, Wurst W, Loomis CA, Joyner AL. Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation. Genes & Development. 14: 1377-89. PMID 10837030 DOI: 10.1101/Gad.14.11.1377  0.343
1999 Liu A, Losos K, Joyner AL. FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate. Development (Cambridge, England). 126: 4827-38. PMID 10518499  0.321
1999 Mintz L, Galperin E, Pasmanik-Chor M, Tulzinsky S, Bromberg Y, Kozak CA, Joyner A, Fein A, Horowitz M. EHD1--an EH-domain-containing protein with a specific expression pattern. Genomics. 59: 66-76. PMID 10395801 DOI: 10.1006/geno.1999.5800  0.359
1999 Nakashima M, Toyono T, Akamine A, Joyner A. Expression of growth/differentiation factor 11, a new member of the BMP/TGFbeta superfamily during mouse embryogenesis. Mechanisms of Development. 80: 185-9. PMID 10072786 DOI: 10.1016/S0925-4773(98)00205-6  0.384
1998 Hanks MC, Loomis CA, Harris E, Tong CX, Anson-Cartwright L, Auerbach A, Joyner A. Drosophila engrailed can substitute for mouse Engrailed1 function in mid-hindbrain, but not limb development. Development (Cambridge, England). 125: 4521-30. PMID 9778510  0.339
1998 Liu A, Joyner AL, Turnbull DH. Alteration of limb and brain patterning in early mouse embryos by ultrasound-guided injection of Shh-expressing cells. Mechanisms of Development. 75: 107-15. PMID 9739117 DOI: 10.1016/S0925-4773(98)00090-2  0.348
1998 Zinyk DL, Mercer EH, Harris E, Anderson DJ, Joyner AL. Fate mapping of the mouse midbrain-hindbrain constriction using a site-specific recombination system. Current Biology : Cb. 8: 665-8. PMID 9635195 DOI: 10.1016/S0960-9822(98)70255-6  0.307
1998 Loomis CA, Kimmel RA, Tong CX, Michaud J, Joyner AL. Analysis of the genetic pathway leading to formation of ectopic apical ectodermal ridges in mouse Engrailed-1 mutant limbs. Development (Cambridge, England). 125: 1137-48. PMID 9463360  0.321
1997 Wassef M, Joyner AL. Early mesencephalon/metencephalon patterning and development of the cerebellum. Perspectives On Developmental Neurobiology. 5: 3-16. PMID 9509514  0.372
1997 Kuemerle B, Zanjani H, Joyner A, Herrup K. Pattern deformities and cell loss in Engrailed-2 mutant mice suggest two separate patterning events during cerebellar development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 7881-9. PMID 9315908 DOI: 10.1523/Jneurosci.17-20-07881.1997  0.458
1997 Wassarman KM, Lewandoski M, Campbell K, Joyner AL, Rubenstein JL, Martinez S, Martin GR. Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function. Development (Cambridge, England). 124: 2923-34. PMID 9247335  0.785
1996 Vogel MW, Ji Z, Millen K, Joyner AL. The Engrailed-2 homeobox gene and patterning of spinocerebellar mossy fiber afferents. Brain Research. Developmental Brain Research. 96: 210-8. PMID 8922683 DOI: 10.1016/0165-3806(96)00122-8  0.589
1996 Gerlai R, Millen KJ, Herrup K, Fabien K, Joyner AL, Roder J. Impaired motor learning performance in cerebellar En-2 mutant mice. Behavioral Neuroscience. 110: 126-33. PMID 8652061 DOI: 10.1037/0735-7044.110.1.126  0.552
1996 Forrester LM, Nagy A, Sam M, Watt A, Stevenson L, Bernstein A, Joyner AL, Wurst W. An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro. Proceedings of the National Academy of Sciences of the United States of America. 93: 1677-82. PMID 8643689 DOI: 10.1073/Pnas.93.4.1677  0.487
1996 Song DL, Chalepakis G, Gruss P, Joyner AL. Two Pax-binding sites are required for early embryonic brain expression of an Engrailed-2 transgene. Development (Cambridge, England). 122: 627-35. PMID 8625814  0.311
1995 Millen KJ, Hui CC, Joyner AL. A role for En-2 and other murine homologues of Drosophila segment polarity genes in regulating positional information in the developing cerebellum. Development (Cambridge, England). 121: 3935-45. PMID 8575294  0.629
1995 Guillemot F, Caspary T, Tilghman SM, Copeland NG, Gilbert DJ, Jenkins NA, Anderson DJ, Joyner AL, Rossant J, Nagy A. Genomic imprinting of Mash2, a mouse gene required for trophoblast development. Nature Genetics. 9: 235-42. PMID 7773285 DOI: 10.1038/Ng0395-235  0.543
1995 Wurst W, Rossant J, Prideaux V, Kownacka M, Joyner A, Hill DP, Guillemot F, Gasca S, Cado D, Auerbach A. A large-scale gene-trap screen for insertional mutations in developmentally regulated genes in mice. Genetics. 139: 889-99. PMID 7713439  0.325
1995 Duyao MP, Auerbach AB, Ryan A, Persichetti F, Barnes GT, McNeil SM, Ge P, Vonsattel JP, Gusella JF, Joyner AL. Inactivation of the mouse Huntington's disease gene homolog Hdh. Science (New York, N.Y.). 269: 407-10. PMID 7618107 DOI: 10.1126/Science.7618107  0.378
1994 Joyner AL, Guillemot F. Gene targeting and development of the nervous system. Current Opinion in Neurobiology. 4: 37-42. PMID 8173323  0.579
1994 Hui CC, Slusarski D, Platt KA, Holmgren R, Joyner AL. Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development. Developmental Biology. 162: 402-13. PMID 8150204 DOI: 10.1006/Dbio.1994.1097  0.301
1994 Guillemot F, Nagy A, Auerbach A, Rossant J, Joyner AL. Essential role of Mash-2 in extraembryonic development. Nature. 371: 333-6. PMID 8090202 DOI: 10.1038/371333A0  0.588
1994 Wurst W, Auerbach AB, Joyner AL. Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum. Development (Cambridge, England). 120: 2065-75. PMID 7925010  0.326
1994 Millen KJ, Wurst W, Herrup K, Joyner AL. Abnormal embryonic cerebellar development and patterning of postnatal foliation in two mouse Engrailed-2 mutants. Development (Cambridge, England). 120: 695-706. PMID 7909289  0.633
1994 Lo L, Guillemot F, Joyner AL, Anderson DJ. MASH-1: a marker and a mutation for mammalian neural crest development. Perspectives On Developmental Neurobiology. 2: 191-201. PMID 7728503  0.338
1993 Guillemot F, Lo LC, Johnson JE, Auerbach A, Anderson DJ, Joyner AL. Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons. Cell. 75: 463-76. PMID 8221886 DOI: 10.1016/0092-8674(93)90381-Y  0.597
1993 Guillemot F, Joyner AL. Dynamic expression of the murine Achaete-Scute homologue Mash-1 in the developing nervous system. Mechanisms of Development. 42: 171-85. PMID 8217843  0.595
1993 Logan C, Khoo WK, Cado D, Joyner AL. Two enhancer regions in the mouse En-2 locus direct expression to the mid/hindbrain region and mandibular myoblasts. Development (Cambridge, England). 117: 905-16. PMID 8100765  0.311
1992 McMahon AP, Joyner AL, Bradley A, McMahon JA. The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum. Cell. 69: 581-95. PMID 1534034 DOI: 10.1016/0092-8674(92)90222-X  0.347
1992 Joyner AL, Auerbach A, Skarnes WC. The gene trap approach in embryonic stem cells: the potential for genetic screens in mice. Ciba Foundation Symposium. 165: 277-88; discussion 2. PMID 1516474  0.318
1991 Davis CA, Holmyard DP, Millen KJ, Joyner AL. Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum. Development (Cambridge, England). 111: 287-98. PMID 1680044  0.594
1991 Joyner AL, Herrup K, Auerbach BA, Davis CA, Rossant J. Subtle cerebellar phenotype in mice homozygous for a targeted deletion of the En-2 homeobox. Science (New York, N.Y.). 251: 1239-43. PMID 1672471 DOI: 10.1126/Science.1672471  0.316
1990 Martin GR, Richman M, Reinsch S, Nadeau JH, Joyner A. Mapping of the two mouse engrailed-like genes: close linkage of En-1 to dominant hemimelia (Dh) on chromosome 1 and of En-2 to hemimelic extra-toes (Hx) on chromosome 5. Genomics. 6: 302-8. PMID 2307472 DOI: 10.1016/0888-7543(90)90570-K  0.544
1989 Joyner AL, Skarnes WC, Rossant J. Production of a mutation in mouse En-2 gene by homologous recombination in embryonic stem cells. Nature. 338: 153-6. PMID 2563902 DOI: 10.1038/338153A0  0.331
1989 Gossler A, Joyner AL, Rossant J, Skarnes WC. Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes. Science (New York, N.Y.). 244: 463-5. PMID 2497519 DOI: 10.1126/Science.2497519  0.334
1988 Martin GR, Joyner A, Silver LM, Lehrach H, Bucan M. Analysis of a lethal mutation (tw18) in the mouse t-complex. Progress in Clinical and Biological Research. 284: 147-61. PMID 3064101  0.489
1988 Davis CA, Joyner AL. Expression patterns of the homeo box-containing genes En-1 and En-2 and the proto-oncogene int-1 diverge during mouse development. Genes & Development. 2: 1736-44. PMID 2907320  0.348
1988 Davis CA, Noble-Topham SE, Rossant J, Joyner AL. Expression of the homeo box-containing gene En-2 delineates a specific region of the developing mouse brain. Genes & Development. 2: 361-71. PMID 2454212  0.346
1987 Joyner AL, Martin GR. En-1 and En-2, two mouse genes with sequence homology to the Drosophila engrailed gene: expression during embryogenesis. Genes & Development. 1: 29-38. PMID 2892757  0.583
1987 Martin GR, Silver LM, Fox HS, Joyner AL. Establishment of embryonic stem cell lines from preimplantation mouse embryos homozygous for lethal mutations in the t-complex. Developmental Biology. 121: 20-8. PMID 2883053 DOI: 10.1016/0012-1606(87)90134-5  0.685
1987 Wolgemuth DJ, Viviano CM, Gizang-Ginsberg E, Frohman MA, Joyner AL, Martin GR. Differential expression of the mouse homeobox-containing gene Hox-1.4 during male germ cell differentiation and embryonic development. Proceedings of the National Academy of Sciences of the United States of America. 84: 5813-7. PMID 2441396  0.36
1985 Joyner A, Hauser C, Kornberg T, Tjian R, Martin G. Structure and expression of two classes of mammalian homeo-box-containing genes. Cold Spring Harbor Symposia On Quantitative Biology. 50: 291-300. PMID 3006990 DOI: 10.1101/Sqb.1985.050.01.037  0.553
1983 Rubin JS, Joyner AL, Bernstein A, Whitmore GF. Molecular identification of a human DNA repair gene following DNA-mediated gene transfer. Nature. 306: 206-8. PMID 6417541 DOI: 10.1038/306206A0  0.38
1983 Joyner AL, Bernstein A. Retrovirus transduction: segregation of the viral transforming function and the herpes simplex virus tk gene in infectious Friend spleen focus-forming virus thymidine kinase vectors. Molecular and Cellular Biology. 3: 2191-202. PMID 6318088  0.401
1983 Joyner AL, Bernstein A. Retrovirus transduction: generation of infectious retroviruses expressing dominant and selectable genes is associated with in vivo recombination and deletion events. Molecular and Cellular Biology. 3: 2180-90. PMID 6318087  0.424
1983 Joyner A, Keller G, Phillips RA, Bernstein A. Retrovirus transfer of a bacterial gene into mouse haematopoietic progenitor cells. Nature. 305: 556-8. PMID 6312324 DOI: 10.1038/305556A0  0.503
1982 Joyner A, Yamamoto Y, Bernstein A. Retrovirus long terminal repeats activate expression of coding sequences for the herpes simplex virus thymidine kinase gene. Proceedings of the National Academy of Sciences of the United States of America. 79: 1573-7. PMID 6280191  0.432
1981 Yamamoto Y, Gamble CL, Clark SP, Joyner A, Shibuya T, MacDonald ME, Mager D, Bernstein A, Mak TW. Clonal analysis of early and late stages of erythroleukemia induced by molecular clones of integrated spleen focus-forming virus. Proceedings of the National Academy of Sciences of the United States of America. 78: 6893-7. PMID 6273894 DOI: 10.1073/Pnas.78.11.6893  0.652
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