Nathaniel Heintz - Publications

Rockefeller University, New York, NY, United States 

166 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Mulvey B, Bhatti DL, Gyawali S, Lake AM, Kriaucionis S, Ford CP, Bruchas MR, Heintz N, Dougherty JD. Molecular and Functional Sex Differences of Noradrenergic Neurons in the Mouse Locus Coeruleus. Cell Reports. 23: 2225-2235. PMID 29791834 DOI: 10.1016/j.celrep.2018.04.054  0.64
2018 Nakayama H, Ibañez-Tallon I, Heintz N. Cell-type specific contributions of medial prefrontal neurons to flexible behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29650697 DOI: 10.1523/JNEUROSCI.3537-17.2018  0.6
2017 Ables JL, Görlich A, Antolin-Fontes B, Wang C, Lipford SM, Riad MH, Ren J, Hu F, Luo M, Kenny PJ, Heintz N, Ibañez-Tallon I. Retrograde inhibition by a specific subset of interpeduncular α5 nicotinic neurons regulates nicotine preference. Proceedings of the National Academy of Sciences of the United States of America. PMID 29158387 DOI: 10.1073/pnas.1717506114  0.6
2017 Mellén M, Ayata P, Heintz N. 5-hydroxymethylcytosine accumulation in postmitotic neurons results in functional demethylation of expressed genes. Proceedings of the National Academy of Sciences of the United States of America. PMID 28847947 DOI: 10.1073/pnas.1708044114  0.68
2017 Nectow AR, Moya MV, Ekstrand MI, Mousa A, McGuire KL, Sferrazza CE, Field BC, Rabinowitz GS, Sawicka K, Liang Y, Friedman JM, Heintz N, Schmidt EF. Rapid Molecular Profiling of Defined Cell Types Using Viral TRAP. Cell Reports. 19: 655-667. PMID 28423326 DOI: 10.1016/j.celrep.2017.03.048  0.64
2016 Abraira VE, Kuehn ED, Chirila AM, Springel MW, Toliver AA, Zimmerman AL, Orefice LL, Boyle KA, Bai L, Song BJ, Bashista KA, O'Neill TG, Zhuo J, Tsan C, Hoynoski J, ... ... Heintz N, et al. The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn. Cell. PMID 28041852 DOI: 10.1016/j.cell.2016.12.010  0.44
2016 Li K, Nakajima M, Ibañez-Tallon I, Heintz N. A Cortical Circuit for Sexually Dimorphic Oxytocin-Dependent Anxiety Behaviors. Cell. PMID 27641503 DOI: 10.1016/j.cell.2016.08.067  0.64
2015 Miyoshi G, Young A, Petros T, Karayannis T, McKenzie Chang M, Lavado A, Iwano T, Nakajima M, Taniguchi H, Huang ZJ, Heintz N, Oliver G, Matsuzaki F, Machold RP, Fishell G. Prox1 Regulates the Subtype-Specific Development of Caudal Ganglionic Eminence-Derived GABAergic Cortical Interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 12869-89. PMID 26377473 DOI: 10.1523/JNEUROSCI.1164-15.2015  0.64
2015 Shrestha P, Mousa A, Heintz N. Layer 2/3 pyramidal cells in the medial prefrontal cortex moderate stress induced depressive behaviors. Elife. 4. PMID 26371510 DOI: 10.7554/eLife.08752  1
2014 Sagi Y, Heiman M, Peterson JD, Musatov S, Scarduzio M, Logan SM, Kaplitt MG, Surmeier DJ, Heintz N, Greengard P. Nitric oxide regulates synaptic transmission between spiny projection neurons. Proceedings of the National Academy of Sciences of the United States of America. 111: 17636-41. PMID 25413364 DOI: 10.1073/pnas.1420162111  1
2014 Nakajima M, Görlich A, Heintz N. Oxytocin modulates female sociosexual behavior through a specific class of prefrontal cortical interneurons. Cell. 159: 295-305. PMID 25303526 DOI: 10.1016/j.cell.2014.09.020  1
2014 McKnight NC, Zhong Y, Wold MS, Gong S, Phillips GR, Dou Z, Zhao Y, Heintz N, Zong WX, Yue Z. Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex. Plos Genetics. 10: e1004626. PMID 25275521 DOI: 10.1371/journal.pgen.1004626  1
2014 Heiman M, Kulicke R, Fenster RJ, Greengard P, Heintz N. Cell type-specific mRNA purification by translating ribosome affinity purification (TRAP). Nature Protocols. 9: 1282-91. PMID 24810037 DOI: 10.1038/nprot.2014.085  1
2014 Anthony TE, Dee N, Bernard A, Lerchner W, Heintz N, Anderson DJ. Control of stress-induced persistent anxiety by an extra-amygdala septohypothalamic circuit. Cell. 156: 522-36. PMID 24485458 DOI: 10.1016/j.cell.2013.12.040  1
2013 Gerfen CR, Paletzki R, Heintz N. GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits. Neuron. 80: 1368-83. PMID 24360541 DOI: 10.1016/j.neuron.2013.10.016  1
2013 Fishell G, Heintz N. The neuron identity problem: form meets function. Neuron. 80: 602-12. PMID 24183013 DOI: 10.1016/j.neuron.2013.10.035  1
2013 Rommel PC, Bosque D, Gitlin AD, Croft GF, Heintz N, Casellas R, Nussenzweig MC, Kriaucionis S, Robbiani DF. Fate mapping for activation-induced cytidine deaminase (AID) marks non-lymphoid cells during mouse development. Plos One. 8: e69208. PMID 23861962 DOI: 10.1371/journal.pone.0069208  1
2013 Lanoue V, Usardi A, Sigoillot SM, Talleur M, Iyer K, Mariani J, Isope P, Vodjdani G, Heintz N, Selimi F. The adhesion-GPCR BAI3, a gene linked to psychiatric disorders, regulates dendrite morphogenesis in neurons. Molecular Psychiatry. 18: 943-50. PMID 23628982 DOI: 10.1038/mp.2013.46  1
2013 Schmidt EF, Kus L, Gong S, Heintz N. BAC transgenic mice and the GENSAT database of engineered mouse strains. Cold Spring Harbor Protocols. 2013. PMID 23457350 DOI: 10.1101/pdb.top073692  1
2013 Dalal J, Roh JH, Maloney SE, Akuffo A, Shah S, Yuan H, Wamsley B, Jones WB, de Guzman Strong C, Gray PA, Holtzman DM, Heintz N, Dougherty JD. Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation. Genes & Development. 27: 565-78. PMID 23431030 DOI: 10.1101/gad.207654.112  1
2013 Dougherty JD, Maloney SE, Wozniak DF, Rieger MA, Sonnenblick L, Coppola G, Mahieu NG, Zhang J, Cai J, Patti GJ, Abrahams BS, Geschwind DH, Heintz N. The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2732-53. PMID 23407934 DOI: 10.1523/JNEUROSCI.4762-12.2013  1
2012 Mellén M, Ayata P, Dewell S, Kriaucionis S, Heintz N. MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell. 151: 1417-30. PMID 23260135 DOI: 10.1016/j.cell.2012.11.022  1
2012 Lerner AG, Upton JP, Praveen PV, Ghosh R, Nakagawa Y, Igbaria A, Shen S, Nguyen V, Backes BJ, Heiman M, Heintz N, Greengard P, Hui S, Tang Q, Trusina A, et al. IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. Cell Metabolism. 16: 250-64. PMID 22883233 DOI: 10.1016/j.cmet.2012.07.007  1
2012 Dougherty JD, Zhang J, Feng H, Gong S, Heintz N. Mouse transgenesis in a single locus with independent regulation for multiple fluorophores. Plos One. 7: e40511. PMID 22808177 DOI: 10.1371/journal.pone.0040511  1
2012 Heller EA, Zhang W, Selimi F, Earnheart JC, ?limak MA, Santos-Torres J, Ibañez-Tallon I, Aoki C, Chait BT, Heintz N. The biochemical anatomy of cortical inhibitory synapses. Plos One. 7: e39572. PMID 22768092 DOI: 10.1371/journal.pone.0039572  1
2012 Chan CS, Peterson JD, Gertler TS, Glajch KE, Quintana RE, Cui Q, Sebel LE, Plotkin JL, Shen W, Heiman M, Heintz N, Greengard P, Surmeier DJ. Strain-specific regulation of striatal phenotype in Drd2-eGFP BAC transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9124-32. PMID 22764222 DOI: 10.1523/JNEUROSCI.0229-12.2012  1
2012 Warner-Schmidt JL, Schmidt EF, Marshall JJ, Rubin AJ, Arango-Lievano M, Kaplitt MG, Ibañez-Tallon I, Heintz N, Greengard P. Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior. Proceedings of the National Academy of Sciences of the United States of America. 109: 11360-5. PMID 22733786 DOI: 10.1073/pnas.1209293109  1
2012 Tien AC, Tsai HH, Molofsky AV, McMahon M, Foo LC, Kaul A, Dougherty JD, Heintz N, Gutmann DH, Barres BA, Rowitch DH. Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord. Development (Cambridge, England). 139: 2477-87. PMID 22675209 DOI: 10.1242/dev.077214  1
2012 Schmidt EF, Warner-Schmidt JL, Otopalik BG, Pickett SB, Greengard P, Heintz N. Identification of the cortical neurons that mediate antidepressant responses. Cell. 149: 1152-63. PMID 22632977 DOI: 10.1016/j.cell.2012.03.038  1
2012 Walker BA, Hengst U, Kim HJ, Jeon NL, Schmidt EF, Heintz N, Milner TA, Jaffrey SR. Reprogramming axonal behavior by axon-specific viral transduction. Gene Therapy. 19: 947-55. PMID 22278412 DOI: 10.1038/gt.2011.217  1
2012 Tien AC, Tsai HH, Molofsky AV, McMahon M, Foo LC, Kaul A, Dougherty JD, Heintz N, Gutmann DH, Barres BA, Rowitch DH. Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord Journal of Cell Science. 125: 2477-2487.  1
2011 Li L, Rutlin M, Abraira VE, Cassidy C, Kus L, Gong S, Jankowski MP, Luo W, Heintz N, Koerber HR, Woodbury CJ, Ginty DD. The functional organization of cutaneous low-threshold mechanosensory neurons. Cell. 147: 1615-27. PMID 22196735 DOI: 10.1016/j.cell.2011.11.027  1
2011 Luo Z, Volkow ND, Heintz N, Pan Y, Du C. Acute cocaine induces fast activation of D1 receptor and progressive deactivation of D2 receptor striatal neurons: in vivo optical microprobe [Ca2+]i imaging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 13180-90. PMID 21917801 DOI: 10.1523/JNEUROSCI.2369-11.2011  1
2011 Yang Z, Jiang H, Chaichanasakul T, Gong S, Yang XW, Heintz N, Lin S. Corrigendum to " Modified bacterial artificial chromosomes for zebrafish transgenesis" Methods 39 (2006) 183-188 Methods. 53: 327. DOI: 10.1016/j.ymeth.2010.11.001  1
2010 Morishita H, Miwa JM, Heintz N, Hensch TK. Lynx1, a cholinergic brake, limits plasticity in adult visual cortex. Science (New York, N.Y.). 330: 1238-40. PMID 21071629 DOI: 10.1126/science.1195320  1
2010 Chao HT, Chen H, Samaco RC, Xue M, Chahrour M, Yoo J, Neul JL, Gong S, Lu HC, Heintz N, Ekker M, Rubenstein JL, Noebels JL, Rosenmund C, Zoghbi HY. Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes. Nature. 468: 263-9. PMID 21068835 DOI: 10.1038/nature09582  1
2010 Borroto-Escuela DO, Romero-Fernandez W, Tarakanov AO, Gómez-Soler M, Corrales F, Marcellino D, Narvaez M, Frankowska M, Flajolet M, Heintz N, Agnati LF, Ciruela F, Fuxe K. Characterization of the A2AR-D2R interface: focus on the role of the C-terminal tail and the transmembrane helices. Biochemical and Biophysical Research Communications. 402: 801-7. PMID 21040702 DOI: 10.1016/j.bbrc.2010.10.122  1
2010 Gong S, Kus L, Heintz N. Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis. Nature Protocols. 5: 1678-96. PMID 20885380 DOI: 10.1038/nprot.2010.131  1
2010 Dougherty JD, Schmidt EF, Nakajima M, Heintz N. Analytical approaches to RNA profiling data for the identification of genes enriched in specific cells. Nucleic Acids Research. 38: 4218-30. PMID 20308160 DOI: 10.1093/nar/gkq130  1
2010 Borroto-Escuela DO, Marcellino D, Narvaez M, Flajolet M, Heintz N, Agnati L, Ciruela F, Fuxe K. A serine point mutation in the adenosine A2AR C-terminal tail reduces receptor heteromerization and allosteric modulation of the dopamine D2R. Biochemical and Biophysical Research Communications. 394: 222-7. PMID 20197060 DOI: 10.1016/j.bbrc.2010.02.168  1
2010 Groh A, Meyer HS, Schmidt EF, Heintz N, Sakmann B, Krieger P. Cell-type specific properties of pyramidal neurons in neocortex underlying a layout that is modifiable depending on the cortical area. Cerebral Cortex (New York, N.Y. : 1991). 20: 826-36. PMID 19643810 DOI: 10.1093/cercor/bhp152  1
2009 Siegert S, Scherf BG, Del Punta K, Didkovsky N, Heintz N, Roska B. Genetic address book for retinal cell types. Nature Neuroscience. 12: 1197-204. PMID 19648912 DOI: 10.1038/nn.2370  1
2009 Selimi F, Cristea IM, Heller E, Chait BT, Heintz N. Proteomic studies of a single CNS synapse type: the parallel fiber/purkinje cell synapse. Plos Biology. 7: e83. PMID 19402746 DOI: 10.1371/journal.pbio.1000083  1
2009 Kriaucionis S, Heintz N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science (New York, N.Y.). 324: 929-30. PMID 19372393 DOI: 10.1126/science.1169786  1
2009 Zhong Y, Wang QJ, Li X, Yan Y, Backer JM, Chait BT, Heintz N, Yue Z. Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nature Cell Biology. 11: 468-76. PMID 19270693 DOI: 10.1038/ncb1854  1
2009 Tekinay AB, Nong Y, Miwa JM, Lieberam I, Ibanez-Tallon I, Greengard P, Heintz N. A role for LYNX2 in anxiety-related behavior. Proceedings of the National Academy of Sciences of the United States of America. 106: 4477-82. PMID 19246390 DOI: 10.1073/pnas.0813109106  1
2009 Doyle JP, Dougherty JD, Heiman M, Schmidt EF, Stevens TR, Ma G, Bupp S, Shrestha P, Shah RD, Doughty ML, Gong S, Greengard P, Heintz N. Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types (DOI:10.1016/j.cell.2008.10.029) Cell. 139: 1022. DOI: 10.1016/j.cell.2009.11.011  1
2008 Chadman KK, Gong S, Scattoni ML, Boltuck SE, Gandhy SU, Heintz N, Crawley JN. Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice. Autism Research : Official Journal of the International Society For Autism Research. 1: 147-58. PMID 19360662 DOI: 10.1002/aur.22  1
2008 Doyle JP, Dougherty JD, Heiman M, Schmidt EF, Stevens TR, Ma G, Bupp S, Shrestha P, Shah RD, Doughty ML, Gong S, Greengard P, Heintz N. Application of a translational profiling approach for the comparative analysis of CNS cell types. Cell. 135: 749-62. PMID 19013282 DOI: 10.1016/j.cell.2008.10.029  1
2008 Heiman M, Schaefer A, Gong S, Peterson JD, Day M, Ramsey KE, Suárez-Fariñas M, Schwarz C, Stephan DA, Surmeier DJ, Greengard P, Heintz N. A translational profiling approach for the molecular characterization of CNS cell types. Cell. 135: 738-48. PMID 19013281 DOI: 10.1016/j.cell.2008.10.028  1
2008 Anthony TE, Heintz N. Genetic lineage tracing defines distinct neurogenic and gliogenic stages of ventral telencephalic radial glial development. Neural Development. 3: 30. PMID 18986511 DOI: 10.1186/1749-8104-3-30  1
2008 Drenan RM, Grady SR, Whiteaker P, McClure-Begley T, McKinney S, Miwa JM, Bupp S, Heintz N, McIntosh JM, Bencherif M, Marks MJ, Lester HA. In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors. Neuron. 60: 123-36. PMID 18940593 DOI: 10.1016/j.neuron.2008.09.009  1
2008 Nishi A, Kuroiwa M, Miller DB, O'Callaghan JP, Bateup HS, Shuto T, Sotogaku N, Fukuda T, Heintz N, Greengard P, Snyder GL. Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10460-71. PMID 18923023 DOI: 10.1523/JNEUROSCI.2518-08.2008  1
2008 Bateup HS, Svenningsson P, Kuroiwa M, Gong S, Nishi A, Heintz N, Greengard P. Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs. Nature Neuroscience. 11: 932-9. PMID 18622401 DOI: 10.1038/nn.2153  1
2007 Gong S, Doughty M, Harbaugh CR, Cummins A, Hatten ME, Heintz N, Gerfen CR. Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9817-23. PMID 17855595 DOI: 10.1523/JNEUROSCI.2707-07.2007  1
2007 Gorokhova S, Bibert S, Geering K, Heintz N. A novel family of transmembrane proteins interacting with beta subunits of the Na,K-ATPase. Human Molecular Genetics. 16: 2394-410. PMID 17606467 DOI: 10.1093/hmg/ddm167  1
2007 Head K, Gong S, Joseph S, Wang C, Burkhardt T, Rossi MR, LaDuca J, Matsui S, Vaughan M, Hicks DG, Heintz N, Cowell JK. Defining the expression pattern of the LGI1 gene in BAC transgenic mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 328-37. PMID 17565425 DOI: 10.1007/s00335-007-9024-6  1
2007 Chang SY, Zagha E, Kwon ES, Ozaita A, Bobik M, Martone ME, Ellisman MH, Heintz N, Rudy B. Distribution of Kv3.3 potassium channel subunits in distinct neuronal populations of mouse brain. The Journal of Comparative Neurology. 502: 953-72. PMID 17444489 DOI: 10.1002/cne.21353  1
2007 Anthony TE, Heintz N. The folate metabolic enzyme ALDH1L1 is restricted to the midline of the early CNS, suggesting a role in human neural tube defects. The Journal of Comparative Neurology. 500: 368-83. PMID 17111379 DOI: 10.1002/cne.21179  1
2006 Miwa JM, Stevens TR, King SL, Caldarone BJ, Ibanez-Tallon I, Xiao C, Fitzsimonds RM, Pavlides C, Lester HA, Picciotto MR, Heintz N. The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo. Neuron. 51: 587-600. PMID 16950157 DOI: 10.1016/j.neuron.2006.07.025  1
2006 Wang QJ, Ding Y, Kohtz DS, Kohtz S, Mizushima N, Cristea IM, Rout MP, Chait BT, Zhong Y, Heintz N, Yue Z. Induction of autophagy in axonal dystrophy and degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8057-68. PMID 16885219 DOI: 10.1523/JNEUROSCI.2261-06.2006  1
2006 Yang Z, Jiang H, Chaichanasakul T, Chachainasakul T, Gong S, Yang XW, Heintz N, Lin S. Modified bacterial artificial chromosomes for zebrafish transgenesis. Methods (San Diego, Calif.). 39: 183-8. PMID 16828309 DOI: 10.1016/j.ymeth.2006.04.011  1
2005 Rubinsztein DC, DiFiglia M, Heintz N, Nixon RA, Qin ZH, Ravikumar B, Stefanis L, Tolkovsky A. Autophagy and its possible roles in nervous system diseases, damage and repair. Autophagy. 1: 11-22. PMID 16874045  1
2005 Selimi F, Heintz N. How neurons keep in touch. Nature Neuroscience. 8: 1417-8. PMID 16251974 DOI: 10.1038/nn1105-1417  1
2005 Hatten ME, Heintz N. Large-scale genomic approaches to brain development and circuitry. Annual Review of Neuroscience. 28: 89-108. PMID 16022591 DOI: 10.1146/annurev.neuro.26.041002.131436  1
2005 Gu X, Li C, Wei W, Lo V, Gong S, Li SH, Iwasato T, Itohara S, Li XJ, Mody I, Heintz N, Yang XW. Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice. Neuron. 46: 433-44. PMID 15882643 DOI: 10.1016/j.neuron.2005.03.025  1
2005 Anthony TE, Heintz N. Cre-ating somatic cell genetic mosaics in the mouse. Cell. 121: 322-3. PMID 15882615 DOI: 10.1016/j.cell.2005.04.019  1
2005 Anthony TE, Mason HA, Gridley T, Fishell G, Heintz N. Brain lipid-binding protein is a direct target of Notch signaling in radial glial cells. Genes & Development. 19: 1028-33. PMID 15879553 DOI: 10.1101/gad.1302105  1
2004 Heintz N. Developmental biology: survival by self-digestion. Nature. 432: 963. PMID 15616545 DOI: 10.1038/432963a  1
2004 Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, et al. The knockout mouse project. Nature Genetics. 36: 921-4. PMID 15340423 DOI: 10.1038/ng0904-921  1
2004 Ibañez-Tallon I, Wen H, Miwa JM, Xing J, Tekinay AB, Ono F, Brehm P, Heintz N. Tethering naturally occurring peptide toxins for cell-autonomous modulation of ion channels and receptors in vivo. Neuron. 43: 305-11. PMID 15294139 DOI: 10.1016/j.neuron.2004.07.015  1
2004 Ibañez-Tallon I, Pagenstecher A, Fliegauf M, Olbrich H, Kispert A, Ketelsen UP, North A, Heintz N, Omran H. Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation. Human Molecular Genetics. 13: 2133-41. PMID 15269178 DOI: 10.1093/hmg/ddh219  1
2004 Heintz N. Gene expression nervous system atlas (GENSAT). Nature Neuroscience. 7: 483. PMID 15114362 DOI: 10.1038/nn0504-483  1
2004 Anthony TE, Klein C, Fishell G, Heintz N. Radial glia serve as neuronal progenitors in all regions of the central nervous system. Neuron. 41: 881-90. PMID 15046721 DOI: 10.1016/S0896-6273(04)00140-0  1
2004 Espinosa F, Marks G, Heintz N, Joho RH. Increased motor drive and sleep loss in mice lacking Kv3-type potassium channels. Genes, Brain, and Behavior. 3: 90-100. PMID 15005717 DOI: 10.1046/j.1601-183x.2003.00054.x  1
2003 Yue Z, Jin S, Yang C, Levine AJ, Heintz N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proceedings of the National Academy of Sciences of the United States of America. 100: 15077-82. PMID 14657337 DOI: 10.1073/pnas.2436255100  1
2003 Gong S, Zheng C, Doughty ML, Losos K, Didkovsky N, Schambra UB, Nowak NJ, Joyner A, Leblanc G, Hatten ME, Heintz N. A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature. 425: 917-25. PMID 14586460 DOI: 10.1038/nature02033  1
2003 Heintz N. Biomedicine. Ataxin-1 regulators in the spotlight. Science (New York, N.Y.). 301: 59-60. PMID 12843383 DOI: 10.1126/science.1086311  1
2003 Ibañez-Tallon I, Heintz N, Omran H. To beat or not to beat: roles of cilia in development and disease. Human Molecular Genetics. 12: R27-35. PMID 12668594  1
2002 Gong S, Yang XW, Li C, Heintz N. Highly efficient modification of bacterial artificial chromosomes (BACs) using novel shuttle vectors containing the R6Kgamma origin of replication. Genome Research. 12: 1992-8. PMID 12466304 DOI: 10.1101/gr.476202  1
2002 Yue Z, Horton A, Bravin M, DeJager PL, Selimi F, Heintz N. A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice. Neuron. 35: 921-33. PMID 12372286 DOI: 10.1016/S0896-6273(02)00861-9  1
2002 Ibañez-Tallon I, Gorokhova S, Heintz N. Loss of function of axonemal dynein Mdnah5 causes primary ciliary dyskinesia and hydrocephalus. Human Molecular Genetics. 11: 715-21. PMID 11912187  1
2002 Ibañez-Tallon I, Miwa JM, Wang HL, Adams NC, Crabtree GW, Sine SM, Heintz N. Novel modulation of neuronal nicotinic acetylcholine receptors by association with the endogenous prototoxin lynx1. Neuron. 33: 893-903. PMID 11906696 DOI: 10.1016/S0896-6273(02)00632-3  1
2001 Heintz N. BAC to the future: the use of bac transgenic mice for neuroscience research. Nature Reviews. Neuroscience. 2: 861-70. PMID 11733793 DOI: 10.1038/35104049  1
2001 Misulovin Z, Yang XW, Yu W, Heintz N, Meffre E. A rapid method for targeted modification and screening of recombinant bacterial artificial chromosome. Journal of Immunological Methods. 257: 99-105. PMID 11687243 DOI: 10.1016/S0022-1759(01)00452-5  1
2001 Espinosa F, McMahon A, Chan E, Wang S, Ho CS, Heintz N, Joho RH. Alcohol hypersensitivity, increased locomotion, and spontaneous myoclonus in mice lacking the potassium channels Kv3.1 and Kv3.3. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 6657-65. PMID 11517255  1
2000 Wollmuth LP, Kuner T, Jatzke C, Seeburg PH, Heintz N, Zuo J. The Lurcher mutation identifies delta 2 as an AMPA/kainate receptor-like channel that is potentiated by Ca(2+). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5973-80. PMID 10934245  1
2000 Heintz N. One-hit neuronal death. Nature. 406: 137, 139. PMID 10910338 DOI: 10.1038/35018196  1
2000 Heintz N, Zoghbi HY. Insights from mouse models into the molecular basis of neurodegeneration. Annual Review of Physiology. 62: 779-802. PMID 10845111 DOI: 10.1146/annurev.physiol.62.1.779  1
2000 Doughty ML, De Jager PL, Korsmeyer SJ, Heintz N. Neurodegeneration in Lurcher mice occurs via multiple cell death pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3687-94. PMID 10804210  1
2000 Heintz N. Analysis of mammalian central nervous system gene expression and function using bacterial artificial chromosome-mediated transgenesis. Human Molecular Genetics. 9: 937-43. PMID 10767317  1
2000 Houchens CR, Montigny W, Zeltser L, Dailey L, Gilbert JM, Heintz NM. The dhfr oriβ-binding protein RIP60 contains 15 zinc fingers: DNA binding and looping by the central three fingers and an associated proline-rich region Nucleic Acids Research. 28: 570-581.  1
1999 Yang XW, Wynder C, Doughty ML, Heintz N. BAC-mediated gene-dosage analysis reveals a role for Zipro1 (Ru49/Zfp38) in progenitor cell proliferation in cerebellum and skin. Nature Genetics. 22: 327-35. PMID 10431235 DOI: 10.1038/11896  1
1999 Heintz N, De Jager PL. GluR delta 2 and the development and death of cerebellar Purkinje neurons in lurcher mice. Annals of the New York Academy of Sciences. 868: 502-14. PMID 10414327 DOI: 10.1111/j.1749-6632.1999.tb11319.x  1
1999 Miwa JM, Ibanez-Tallon I, Crabtree GW, Sánchez R, Sali A, Role LW, Heintz N. lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS. Neuron. 23: 105-14. PMID 10402197 DOI: 10.1016/S0896-6273(00)80757-6  1
1998 De Jager PL, Heintz N. The lurcher mutation and ionotropic glutamate receptors: contributions to programmed neuronal death in vivo. Brain Pathology (Zurich, Switzerland). 8: 795-807. PMID 9804384  1
1998 Gubbay J, Doyle JP, Skinner M, Heintz N. Changing patterns of gene expression identify multiple steps during regression of rat prostate in vivo. Endocrinology. 139: 2935-43. PMID 9607804 DOI: 10.1210/endo.139.6.6075  1
1998 De Jager PL, Harvey D, Polydorides AD, Zuo J, Heintz N. A high-resolution genetic map of the nervous locus on mouse chromosome 8. Genomics. 48: 346-53. PMID 9545640 DOI: 10.1006/geno.1997.5193  1
1998 Hu W, Zuo J, De Jager PL, Heintz N. The human glutamate receptor delta 2 gene (GRID2) maps to chromosome 4q22. Genomics. 47: 143-5. PMID 9465309 DOI: 10.1006/geno.1997.5108  1
1997 Yang XW, Model P, Heintz N. Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome. Nature Biotechnology. 15: 859-65. PMID 9306400 DOI: 10.1038/nbt0997-859  1
1997 Rousselot P, Heintz N, Nottebohm F. Expression of brain lipid binding protein in the brain of the adult canary and its implications for adult neurogenesis. The Journal of Comparative Neurology. 385: 415-26. PMID 9300768 DOI: 10.1002/(SICI)1096-9861(19970901)385:3<415::AID-CNE6>3.0.CO;2-6  1
1997 Zuo J, De Jager PL, Takahashi KA, Jiang W, Linden DJ, Heintz N. Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene. Nature. 388: 769-73. PMID 9285588 DOI: 10.1038/42009  1
1997 De Jager PL, Zuo J, Cook SA, Heintz N. A new allele of the lurcher gene, lurcherJ. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 8: 647-50. PMID 9271665 DOI: 10.1007/s003359900530  1
1997 De Jager PL, Zuo J, Heintz N. An approximately 1.2-Mb bacterial artificial chromosome contig refines the genetic and physical maps of the lurcher locus on mouse chromosome 6. Genome Research. 7: 736-46. PMID 9253602  1
1997 Heintz N, Zoghbi H. alpha-Synuclein--a link between Parkinson and Alzheimer diseases? Nature Genetics. 16: 325-7. PMID 9241262 DOI: 10.1038/ng0897-325  1
1997 Arnold DB, Heintz N. A calcium responsive element that regulates expression of two calcium binding proteins in Purkinje cells. Proceedings of the National Academy of Sciences of the United States of America. 94: 8842-7. PMID 9238065 DOI: 10.1073/pnas.94.16.8842  1
1997 Cheng SS, Heintz N. Massive loss of mid- and hindbrain neurons during embryonic development of homozygous lurcher mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 2400-7. PMID 9065501  1
1997 Hatten ME, Alder J, Zimmerman K, Heintz N. Genes involved in cerebellar cell specification and differentiation. Current Opinion in Neurobiology. 7: 40-7. PMID 9039803 DOI: 10.1016/S0959-4388(97)80118-3  1
1996 Segil N, Guermah M, Hoffmann A, Roeder RG, Heintz N. Mitotic regulation of TFIID: inhibition of activator-dependent transcription and changes in subcellular localization. Genes & Development. 10: 2389-400. PMID 8843192  1
1996 Xu LZ, Sánchez R, Sali A, Heintz N. Ligand specificity of brain lipid-binding protein. The Journal of Biological Chemistry. 271: 24711-9. PMID 8798739 DOI: 10.1074/jbc.271.40.24711  1
1996 Heintz N. Ataxia telangiectasia: cell signaling, cell death and the cell cycle. Current Opinion in Neurology. 9: 137-40. PMID 8782982  1
1996 Zeltser L, Desplan C, Heintz N. Hoxb-13: a new Hox gene in a distant region of the HOXB cluster maintains colinearity. Development (Cambridge, England). 122: 2475-84. PMID 8756292  1
1996 Yang XW, Zhong R, Heintz N. Granule cell specification in the developing mouse brain as defined by expression of the zinc finger transcription factor RU49. Development (Cambridge, England). 122: 555-66. PMID 8625807  1
1996 Zheng C, Heintz N, Hatten ME. CNS gene encoding astrotactin, which supports neuronal migration along glial fibers. Science (New York, N.Y.). 272: 417-9. PMID 8602532  1
1995 Zuo J, De Jager PL, Norman DJ, Heintz N. Generation of a high-resolution genetic map and a YAC contig of the Lurcher locus on mouse chromosome 6. Genome Research. 5: 381-92. PMID 8750197  1
1995 Norman DJ, Feng L, Cheng SS, Gubbay J, Chan E, Heintz N. The lurcher gene induces apoptotic death in cerebellar Purkinje cells. Development (Cambridge, England). 121: 1183-93. PMID 7743930  1
1995 Hatten ME, Heintz N. Mechanisms of neural patterning and specification in the developing cerebellum. Annual Review of Neuroscience. 18: 385-408. PMID 7605067 DOI: 10.1146/  1
1995 Feng L, Heintz N. Differentiating neurons activate transcription of the brain lipid-binding protein gene in radial glia through a novel regulatory element. Development (Cambridge, England). 121: 1719-30. PMID 7600988  1
1994 Goldman-Wohl DS, Chan E, Baird D, Heintz N. Kv3.3b: a novel Shaw type potassium channel expressed in terminally differentiated cerebellar Purkinje cells and deep cerebellar nuclei. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 511-22. PMID 8301351  1
1994 Feng L, Hatten ME, Heintz N. Brain lipid-binding protein (BLBP): a novel signaling system in the developing mammalian CNS. Neuron. 12: 895-908. PMID 8161459 DOI: 10.1016/0896-6273(94)90341-7  1
1994 Martinelli R, Heintz N. H1TF2A, the large subunit of a heterodimeric, glutamine-rich CCAAT-binding transcription factor involved in histone H1 cell cycle regulation. Molecular and Cellular Biology. 14: 8322-32. PMID 7969168  1
1994 Arnold D, Feng L, Kim J, Heintz N. A strategy for the analysis of gene expression during neural development. Proceedings of the National Academy of Sciences of the United States of America. 91: 9970-4. PMID 7937928 DOI: 10.1073/pnas.91.21.9970  1
1994 Heintz N. Future trends affecting the lab: The life scientist's view Annals of the New York Academy of Sciences. 735: 10-14. DOI: 10.1111/j.1749-6632.1994.tb31017.x  1
1994 Baird DH, Hatten ME, Heintz N, Mason CA. Micromethods for Analyzing Axon-Target Interactions in Vitro Neuroprotocols. 4: 106-115. DOI: 10.1006/ncmn.1994.1013  1
1993 McKinney JD, Chang F, Heintz N, Cross FR. Negative regulation of FAR1 at the Start of the yeast cell cycle. Genes & Development. 7: 833-43. PMID 8491380  1
1993 Heintz N. Cell death and the cell cycle: a relationship between transformation and neurodegeneration? Trends in Biochemical Sciences. 18: 157-9. PMID 8328013 DOI: 10.1016/0968-0004(93)90103-T  1
1993 Kuhar SG, Feng L, Vidan S, Ross ME, Hatten ME, Heintz N. Changing patterns of gene expression define four stages of cerebellar granule neuron differentiation. Development (Cambridge, England). 117: 97-104. PMID 8223263  1
1991 Fletcher C, Norman DJ, Germond E, Heintz N. A multilocus linkage map of mouse chromosome 8. Genomics. 9: 737-41. PMID 2037298 DOI: 10.1016/0888-7543(91)90368-O  1
1991 Fletcher C, Norman DJ, Heintz N. Genetic mapping of meander tail, a mouse mutation affecting cerebellar development. Genomics. 9: 647-55. PMID 2037292 DOI: 10.1016/0888-7543(91)90358-L  1
1991 Gao WO, Heintz N, Hatten ME. Cerebellar granule cell neurogenesis is regulated by cell-cell interactions in vitro. Neuron. 6: 705-15. PMID 2025426 DOI: 10.1016/0896-6273(91)90168-Y  1
1991 Heintz N. The regulation of histone gene expression during the cell cycle. Biochimica Et Biophysica Acta. 1088: 327-39. PMID 2015297 DOI: 10.1016/0167-4781(91)90122-3  1
1991 La Bella F, Heintz N. Histone gene transcription factor binding in extracts of normal human cells. Molecular and Cellular Biology. 11: 5825-31. PMID 1944265  1
1991 Roberts SB, Segil N, Heintz N. Differential phosphorylation of the transcription factor Oct1 during the cell cycle. Science (New York, N.Y.). 253: 1022-6. PMID 1887216  1
1991 Segil N, Roberts SB, Heintz N. Cell-cycle-regulated phosphorylation of the transcription factor Oct-1. Cold Spring Harbor Symposia On Quantitative Biology. 56: 285-92. PMID 1819493  1
1991 Ovnic M, Swank RT, Fletcher C, Zhen L, Novak EK, Baumann H, Heintz N, Ganschow RE. Characterization and functional expression of a cDNA encoding egasyn (esterase-22): the endoplasmic reticulum-targeting protein of beta-glucuronidase. Genomics. 11: 956-67. PMID 1783403  0.48
1991 McKinney JD, Heintz N. Transcriptional regulation in the eukaryotic cell cycle. Trends in Biochemical Sciences. 16: 430-5. PMID 1776174 DOI: 10.1016/0968-0004(91)90170-Z  1
1991 Segil N, Roberts SB, Heintz N. Mitotic phosphorylation of the Oct-1 homeodomain and regulation of Oct-1 DNA binding activity. Science (New York, N.Y.). 254: 1814-6. PMID 1684878  1
1991 Norman DJ, Fletcher C, Heintz N. Genetic mapping of the lurcher locus on mouse chromosome 6 using an intersubspecific backcross. Genomics. 9: 147-53. PMID 1672287 DOI: 10.1016/0888-7543(91)90232-4  1
1991 Heintz N. Transcriptional regulation: Introduction Trends in Biochemical Sciences. 16: 393.  1
1990 Ross ME, Fletcher C, Mason CA, Hatten ME, Heintz N. Meander tail reveals a discrete developmental unit in the mouse cerebellum. Proceedings of the National Academy of Sciences of the United States of America. 87: 4189-92. PMID 2349228 DOI: 10.1073/pnas.87.11.4189  1
1990 Simon MC, Rooney RJ, Fisch TM, Heintz N, Nevins JR. E1A-dependent trans-activation of the c-fos promoter requires the TATAA sequence. Proceedings of the National Academy of Sciences of the United States of America. 87: 513-7. PMID 2137244  1
1989 Gallinari P, La Bella F, Heintz N. Characterization and purification of H1TF2, a novel CCAAT-binding protein that interacts with a histone H1 subtype-specific consensus element. Molecular and Cellular Biology. 9: 1566-75. PMID 2725515  1
1989 Heintz N. Temporal regulation of gene expression during the mammalian cell cycle. Current Opinion in Cell Biology. 1: 275-8. PMID 2698680 DOI: 10.1016/0955-0674(89)90100-2  1
1989 La Bella F, Gallinari P, McKinney J, Heintz N. Histone H1 subtype-specific consensus elements mediate cell cycle-regulated transcription in vitro. Genes & Development. 3: 1982-90. PMID 2620829  1
1988 O'Neill EA, Fletcher C, Burrow CR, Heintz N, Roeder RG, Kelly TJ. Transcription factor OTF-1 is functionally identical to the DNA replication factor NF-III. Science (New York, N.Y.). 241: 1210-3. PMID 3413485  1
1988 LaBella F, Sive HL, Roeder RG, Heintz N. Cell-cycle regulation of a human histone H2b gene is mediated by the H2b subtype-specific consensus element. Genes & Development. 2: 32-9. PMID 3128460  1
1988 Dailey L, Roberts SB, Heintz N. Purification of the human histone H4 gene-specific transcription factors H4TF-1 and H4TF-2. Genes & Development. 2: 1700-12. PMID 3071490  1
1988 Simon MC, Fisch TM, Benecke BJ, Nevins JR, Heintz N. Definition of multiple, functionally distinct TATA elements, one of which is a target in the hsp70 promoter for E1A regulation. Cell. 52: 723-9. PMID 2830991 DOI: 10.1016/0092-8674(88)90410-2  1
1988 La Bella F, Zhong R, Heintz N. Cell type-specific expression of a human histone H1 gene. The Journal of Biological Chemistry. 263: 2115-8. PMID 2448304  1
1987 Fletcher C, Heintz N, Roeder RG. Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene. Cell. 51: 773-81. PMID 3677172 DOI: 10.1016/0092-8674(87)90100-0  1
1987 Capasso O, Bleecker GC, Heintz N. Sequences controlling histone H4 mRNA abundance. The Embo Journal. 6: 1825-31. PMID 3608993  1
1987 Kaczmarek L, Calabretta B, Kao HT, Heintz N, Nevins J, Baserga R. Control of hsp70 RNA levels in human lymphocytes. The Journal of Cell Biology. 104: 183-7. PMID 3492498  1
1987 Dailey L, Roberts SB, Heintz N. RNA polymerase II transcription factors H4TF-1 and H4TF-2 require metal to bind specific DNA sequences. Molecular and Cellular Biology. 7: 4582-4. PMID 3437898  1
1987 Simon MC, Kitchener K, Kao HT, Hickey E, Weber L, Voellmy R, Heintz N, Nevins JR. Selective induction of human heat shock gene transcription by the adenovirus E1A gene products, including the 12S E1A product. Molecular and Cellular Biology. 7: 2884-90. PMID 2959854  1
1986 Dailey L, Hanly SM, Roeder RG, Heintz N. Distinct transcription factors bind specifically to two regions of the human histone H4 promoter. Proceedings of the National Academy of Sciences of the United States of America. 83: 7241-5. PMID 3463962  1
1986 Sive HL, Heintz N, Roeder RG. Multiple sequence elements are required for maximal in vitro transcription of a human histone H2B gene. Molecular and Cellular Biology. 6: 3329-40. PMID 3025588  1
1985 Hanly SM, Bleecker GC, Heintz N. Identification of promoter elements necessary for transcriptional regulation of a human histone H4 gene in vitro. Molecular and Cellular Biology. 5: 380-9. PMID 3974574  1
1985 Kao HT, Capasso O, Heintz N, Nevins JR. Cell cycle control of the human HSP70 gene: implications for the role of a cellular E1A-like function. Molecular and Cellular Biology. 5: 628-33. PMID 3872994  1
1985 Capasso O, Heintz N. Regulated expression of mammalian histone H4 genes in vivo requires a trans-acting transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 82: 5622-6. PMID 3862085  1
1984 Heintz N, Roeder RG. Transcription of human histone genes in extracts from synchronized HeLa cells. Proceedings of the National Academy of Sciences of the United States of America. 81: 2713-7. PMID 6585823  1
1984 Sive HL, Heintz N, Roeder RG. Regulation of human histone gene expression during the HeLa cell cycle requires protein synthesis. Molecular and Cellular Biology. 4: 2723-34. PMID 6441888  1
1983 Zhong R, Roeder RG, Heintz N. The primary structure and expression of four cloned human histone genes. Nucleic Acids Research. 11: 7409-25. PMID 6647026 DOI: 10.1093/nar/11.21.7409  1
1983 Strayer D, Heintz N, Roeder R, Gillespie D. Three organizations of human DNA. Proceedings of the National Academy of Sciences of the United States of America. 80: 4770-4. PMID 6576359  1
1983 Heintz N, Sive HL, Roeder RG. Regulation of human histone gene expression: kinetics of accumulation and changes in the rate of synthesis and in the half-lives of individual histone mRNAs during the HeLa cell cycle. Molecular and Cellular Biology. 3: 539-50. PMID 6406835  1
1981 Heintz N, Zernik M, Roeder RG. The structure of the human histone genes: clustered but not tandemly repeated. Cell. 24: 661-8. PMID 6265100 DOI: 10.1016/0092-8674(81)90092-1  1
1980 Zernik M, Heintz N, Boime I, Roeder RG. Xenopus laevis histone genes: variant H1 genes are present in different clusters. Cell. 22: 807-15. PMID 7460012 DOI: 10.1016/0092-8674(80)90557-7  1
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