Nathaniel Heintz - Publications

Affiliations: 
Rockefeller University, New York, NY, United States 

281 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Choi S, Hachisuka J, Brett MA, Magee AR, Omori Y, Iqbal NU, Zhang D, DeLisle MM, Wolfson RL, Bai L, Santiago C, Gong S, Goulding M, Heintz N, Koerber HR, et al. Parallel ascending spinal pathways for affective touch and pain. Nature. PMID 33116307 DOI: 10.1038/s41586-020-2860-1  0.52
2020 Shrestha P, Shan Z, Mamcarz M, Ruiz KSA, Zerihoun AT, Juan CY, Herrero-Vidal PM, Pelletier J, Heintz N, Klann E. Amygdala inhibitory neurons as loci for translation in emotional memories. Nature. PMID 33029009 DOI: 10.1038/s41586-020-2793-8  0.72
2020 Heintz N, Gong S. Working with Bacterial Artificial Chromosomes (BACs) and Other High-Capacity Vectors. Cold Spring Harbor Protocols. 2020: pdb.top097998. PMID 33004554 DOI: 10.1101/pdb.top097998  0.52
2020 Heintz N, Gong S. Growth of and Preparation of DNA. Cold Spring Harbor Protocols. 2020: pdb.prot098145. PMID 33004551 DOI: 10.1101/pdb.prot098145  0.52
2020 Heintz N, Gong S. Small-Scale Preparations of Yeast DNA. Cold Spring Harbor Protocols. PMID 32763978 DOI: 10.1101/pdb.prot098152  0.52
2020 Heintz N, Gong S. One-Step Bacterial Artificial Chromosome (BAC) Modification: Transfer of the Reporter Vector into BAC/RecA Cells and Selection of Co-Integrates. Cold Spring Harbor Protocols. 2020: 098137. PMID 32611780 DOI: 10.1101/pdb.prot098137  0.52
2020 Heintz N, Gong S. One-Step Bacterial Artificial Chromosome (BAC) Modification: Transformation of the BAC Host with the RecA Vector. Cold Spring Harbor Protocols. 2020: 098129. PMID 32611779 DOI: 10.1101/pdb.prot098129  0.52
2020 Heintz N, Gong S. One-Step Bacterial Artificial Chromosome (BAC) Modification: Cloning of the A Homology Arm into Reporter-Shuttle Vector. Cold Spring Harbor Protocols. 2020: 098111. PMID 32611778 DOI: 10.1101/pdb.prot098111  0.52
2020 Heintz N, Gong S. One-Step Bacterial Artificial Chromosome (BAC) Modification: Preparation of the A Homology Arm (A-Box). Cold Spring Harbor Protocols. 2020: 098103. PMID 32611777 DOI: 10.1101/pdb.prot098103  0.52
2020 Heintz N, Gong S. One-Step Bacterial Artificial Chromosome (BAC) Modification: Preparation of Plasmids. Cold Spring Harbor Protocols. 2020: 098095. PMID 32611776 DOI: 10.1101/pdb.prot098095  0.52
2020 Roussarie JP, Yao V, Rodriguez-Rodriguez P, Oughtred R, Rust J, Plautz Z, Kasturia S, Albornoz C, Wang W, Schmidt EF, Dannenfelser R, Tadych A, Brichta L, Barnea-Cramer A, Heintz N, et al. Selective Neuronal Vulnerability in Alzheimer's Disease: A Network-Based Analysis. Neuron. PMID 32603655 DOI: 10.1016/j.neuron.2020.06.010  0.88
2020 Heintz N, Gong S. Two-Step Bacterial Artificial Chromosome (BAC) Engineering: Verification of Co-Integrates and Selection of Resolved BAC Clones. Cold Spring Harbor Protocols. 2020: pdb.prot098087. PMID 32238594 DOI: 10.1101/pdb.prot098087  0.52
2020 Heintz N, Gong S. Two-Step Bacterial Artificial Chromosome (BAC) Engineering: Electroporation of Competent BAC Host Cells with the Recombinant Shuttle Vector. Cold Spring Harbor Protocols. 2020: pdb.prot098079. PMID 32238593 DOI: 10.1101/pdb.prot098079  0.52
2020 Heintz N, Gong S. Two-Step Bacterial Artificial Chromosome (BAC) Engineering: Preparation and Verification of the Recombinant Shuttle Vector. Cold Spring Harbor Protocols. 2020: pdb.prot098061. PMID 32238592 DOI: 10.1101/pdb.prot098061  0.52
2020 Heintz N, Gong S. Two-Step Bacterial Artificial Chromosome (BAC) Engineering: Cloning of the A and B Homology Arms into the Shuttle Vector. Cold Spring Harbor Protocols. 2020: pdb.prot098053. PMID 32238591 DOI: 10.1101/pdb.prot098053  0.52
2020 Heintz N, Gong S. Two-Step Bacterial Artificial Chromosome (BAC) Engineering: Preparation of the A Homology Arm (A-Box) and B Homology Arm (B-Box). Cold Spring Harbor Protocols. 2020: pdb.prot098046. PMID 32238590 DOI: 10.1101/pdb.prot098046  0.52
2020 Heintz N, Gong S. Two-Step Bacterial Artificial Chromosome (BAC) Engineering: Preparation of Shuttle Vector DNA. Cold Spring Harbor Protocols. 2020: pdb.prot098038. PMID 32238589 DOI: 10.1101/pdb.prot098038  0.52
2020 Antolin-Fontes B, Li K, Ables JL, Riad MH, Görlich A, Williams M, Wang C, Lipford SM, Dao M, Liu J, Molina H, Heintz N, Kenny PJ, Ibañez-Tallon I. The habenular G-protein-coupled receptor 151 regulates synaptic plasticity and nicotine intake. Proceedings of the National Academy of Sciences of the United States of America. PMID 32098843 DOI: 10.1073/pnas.1916132117  0.6
2020 Shrestha P, Ayata P, Herrero-Vidal P, Longo F, Gastone A, LeDoux JE, Heintz N, Klann E. Cell-type-specific drug-inducible protein synthesis inhibition demonstrates that memory consolidation requires rapid neuronal translation. Nature Neuroscience. PMID 31959934 DOI: 10.1038/s41593-019-0568-z  0.72
2019 Heintz N, Gong S. Examination of Bacterial Artificial Chromosome (BAC) DNA Quality and Quantity by Pulsed-Field Gel Electrophoresis. Cold Spring Harbor Protocols. 2019: pdb.prot098020. PMID 31676579 DOI: 10.1101/pdb.prot098020  0.52
2019 Heintz N, Gong S. Large-Scale Preparation and Linearization of Bacterial Artificial Chromosome (BAC) DNA. Cold Spring Harbor Protocols. 2019: pdb.prot098012. PMID 31676578 DOI: 10.1101/pdb.prot098012  0.52
2019 Heintz N, Gong S. Small-Scale Isolation of Bacterial Artificial Chromosome (BAC) DNA and Verification by Polymerase Chain Reaction (PCR). Cold Spring Harbor Protocols. 2019: pdb.prot098004. PMID 31676577 DOI: 10.1101/pdb.prot098004  0.52
2018 Mulvey B, Bhatti DL, Gyawali S, Lake AM, Kriaucionis S, Ford CP, Bruchas MR, Heintz N, Dougherty JD. Molecular and Functional Sex Differences of Noradrenergic Neurons in the Mouse Locus Coeruleus. Cell Reports. 23: 2225-2235. PMID 29791834 DOI: 10.1016/j.celrep.2018.04.054  0.64
2018 Nakayama H, Ibañez-Tallon I, Heintz N. Cell-type specific contributions of medial prefrontal neurons to flexible behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29650697 DOI: 10.1523/JNEUROSCI.3537-17.2018  0.6
2017 Ables JL, Görlich A, Antolin-Fontes B, Wang C, Lipford SM, Riad MH, Ren J, Hu F, Luo M, Kenny PJ, Heintz N, Ibañez-Tallon I. Retrograde inhibition by a specific subset of interpeduncular α5 nicotinic neurons regulates nicotine preference. Proceedings of the National Academy of Sciences of the United States of America. PMID 29158387 DOI: 10.1073/pnas.1717506114  0.6
2017 Mellén M, Ayata P, Heintz N. 5-hydroxymethylcytosine accumulation in postmitotic neurons results in functional demethylation of expressed genes. Proceedings of the National Academy of Sciences of the United States of America. PMID 28847947 DOI: 10.1073/pnas.1708044114  0.56
2017 Nectow AR, Moya MV, Ekstrand MI, Mousa A, McGuire KL, Sferrazza CE, Field BC, Rabinowitz GS, Sawicka K, Liang Y, Friedman JM, Heintz N, Schmidt EF. Rapid Molecular Profiling of Defined Cell Types Using Viral TRAP. Cell Reports. 19: 655-667. PMID 28423326 DOI: 10.1016/j.celrep.2017.03.048  0.88
2016 Abraira VE, Kuehn ED, Chirila AM, Springel MW, Toliver AA, Zimmerman AL, Orefice LL, Boyle KA, Bai L, Song BJ, Bashista KA, O'Neill TG, Zhuo J, Tsan C, Hoynoski J, ... ... Heintz N, et al. The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn. Cell. PMID 28041852 DOI: 10.1016/j.cell.2016.12.010  0.44
2016 Li K, Nakajima M, Ibañez-Tallon I, Heintz N. A Cortical Circuit for Sexually Dimorphic Oxytocin-Dependent Anxiety Behaviors. Cell. PMID 27641503 DOI: 10.1016/j.cell.2016.08.067  0.64
2015 Miyoshi G, Young A, Petros T, Karayannis T, McKenzie Chang M, Lavado A, Iwano T, Nakajima M, Taniguchi H, Huang ZJ, Heintz N, Oliver G, Matsuzaki F, Machold RP, Fishell G. Prox1 Regulates the Subtype-Specific Development of Caudal Ganglionic Eminence-Derived GABAergic Cortical Interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 12869-89. PMID 26377473 DOI: 10.1523/JNEUROSCI.1164-15.2015  0.64
2015 Shrestha P, Mousa A, Heintz N. Layer 2/3 pyramidal cells in the medial prefrontal cortex moderate stress induced depressive behaviors. Elife. 4. PMID 26371510 DOI: 10.7554/eLife.08752  1
2015 Cunniff B, Newick K, Nelson KJ, Wozniak AN, Beuschel S, Leavitt B, Bhave A, Butnor K, Koenig A, Chouchani ET, James AM, Haynes AC, Lowther WT, Murphy MP, Shukla A, ... Heintz NH, et al. Disabling Mitochondrial Peroxide Metabolism via Combinatorial Targeting of Peroxiredoxin 3 as an Effective Therapeutic Approach for Malignant Mesothelioma. Plos One. 10: e0127310. PMID 26011724 DOI: 10.1371/journal.pone.0127310  0.4
2014 Cunniff B, Wozniak AN, Sweeney P, DeCosta K, Heintz NH. Peroxiredoxin 3 levels regulate a mitochondrial redox setpoint in malignant mesothelioma cells. Redox Biology. 3: 79-87. PMID 25462069 DOI: 10.1016/j.redox.2014.11.003  0.4
2014 Sagi Y, Heiman M, Peterson JD, Musatov S, Scarduzio M, Logan SM, Kaplitt MG, Surmeier DJ, Heintz N, Greengard P. Nitric oxide regulates synaptic transmission between spiny projection neurons. Proceedings of the National Academy of Sciences of the United States of America. 111: 17636-41. PMID 25413364 DOI: 10.1073/pnas.1420162111  1
2014 Nakajima M, Görlich A, Heintz N. Oxytocin modulates female sociosexual behavior through a specific class of prefrontal cortical interneurons. Cell. 159: 295-305. PMID 25303526 DOI: 10.1016/j.cell.2014.09.020  1
2014 McKnight NC, Zhong Y, Wold MS, Gong S, Phillips GR, Dou Z, Zhao Y, Heintz N, Zong WX, Yue Z. Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex. Plos Genetics. 10: e1004626. PMID 25275521 DOI: 10.1371/journal.pgen.1004626  1
2014 Thompson JK, Westbom CM, MacPherson MB, Mossman BT, Heintz NH, Spiess P, Shukla A. Asbestos modulates thioredoxin-thioredoxin interacting protein interaction to regulate inflammasome activation. Particle and Fibre Toxicology. 11: 24. PMID 24885895 DOI: 10.1186/1743-8977-11-24  0.4
2014 Heiman M, Kulicke R, Fenster RJ, Greengard P, Heintz N. Cell type-specific mRNA purification by translating ribosome affinity purification (TRAP). Nature Protocols. 9: 1282-91. PMID 24810037 DOI: 10.1038/nprot.2014.085  1
2014 Cunniff B, Snider GW, Fredette N, Stumpff J, Hondal RJ, Heintz NH. Resolution of oxidative stress by thioredoxin reductase: Cysteine versus selenocysteine. Redox Biology. 2: 475-84. PMID 24624337 DOI: 10.1016/j.redox.2014.01.021  0.4
2014 Anthony TE, Dee N, Bernard A, Lerchner W, Heintz N, Anderson DJ. Control of stress-induced persistent anxiety by an extra-amygdala septohypothalamic circuit. Cell. 156: 522-36. PMID 24485458 DOI: 10.1016/j.cell.2013.12.040  1
2013 Gerfen CR, Paletzki R, Heintz N. GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits. Neuron. 80: 1368-83. PMID 24360541 DOI: 10.1016/j.neuron.2013.10.016  1
2013 Fishell G, Heintz N. The neuron identity problem: form meets function. Neuron. 80: 602-12. PMID 24183013 DOI: 10.1016/j.neuron.2013.10.035  1
2013 Cunniff B, Snider GW, Fredette N, Hondal RJ, Heintz NH. A direct and continuous assay for the determination of thioredoxin reductase activity in cell lysates. Analytical Biochemistry. 443: 34-40. PMID 23973629 DOI: 10.1016/j.ab.2013.08.013  0.4
2013 Rommel PC, Bosque D, Gitlin AD, Croft GF, Heintz N, Casellas R, Nussenzweig MC, Kriaucionis S, Robbiani DF. Fate mapping for activation-induced cytidine deaminase (AID) marks non-lymphoid cells during mouse development. Plos One. 8: e69208. PMID 23861962 DOI: 10.1371/journal.pone.0069208  1
2013 Lanoue V, Usardi A, Sigoillot SM, Talleur M, Iyer K, Mariani J, Isope P, Vodjdani G, Heintz N, Selimi F. The adhesion-GPCR BAI3, a gene linked to psychiatric disorders, regulates dendrite morphogenesis in neurons. Molecular Psychiatry. 18: 943-50. PMID 23628982 DOI: 10.1038/mp.2013.46  1
2013 Schmidt EF, Kus L, Gong S, Heintz N. BAC transgenic mice and the GENSAT database of engineered mouse strains. Cold Spring Harbor Protocols. 2013. PMID 23457350 DOI: 10.1101/pdb.top073692  1
2013 Dalal J, Roh JH, Maloney SE, Akuffo A, Shah S, Yuan H, Wamsley B, Jones WB, de Guzman Strong C, Gray PA, Holtzman DM, Heintz N, Dougherty JD. Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation. Genes & Development. 27: 565-78. PMID 23431030 DOI: 10.1101/gad.207654.112  1
2013 Dougherty JD, Maloney SE, Wozniak DF, Rieger MA, Sonnenblick L, Coppola G, Mahieu NG, Zhang J, Cai J, Patti GJ, Abrahams BS, Geschwind DH, Heintz N. The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2732-53. PMID 23407934 DOI: 10.1523/JNEUROSCI.4762-12.2013  1
2013 Mossman BT, Shukla A, Heintz NH, Verschraegen CF, Thomas A, Hassan R. New insights into understanding the mechanisms, pathogenesis, and management of malignant mesotheliomas. The American Journal of Pathology. 182: 1065-77. PMID 23395095 DOI: 10.1016/j.ajpath.2012.12.028  0.4
2013 Cunniff B, Benson K, Stumpff J, Newick K, Held P, Taatjes D, Joseph J, Kalyanaraman B, Heintz NH. Mitochondrial-targeted nitroxides disrupt mitochondrial architecture and inhibit expression of peroxiredoxin 3 and FOXM1 in malignant mesothelioma cells. Journal of Cellular Physiology. 228: 835-45. PMID 23018647 DOI: 10.1002/jcp.24232  0.4
2012 Mellén M, Ayata P, Dewell S, Kriaucionis S, Heintz N. MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell. 151: 1417-30. PMID 23260135 DOI: 10.1016/j.cell.2012.11.022  1
2012 Lerner AG, Upton JP, Praveen PV, Ghosh R, Nakagawa Y, Igbaria A, Shen S, Nguyen V, Backes BJ, Heiman M, Heintz N, Greengard P, Hui S, Tang Q, Trusina A, et al. IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. Cell Metabolism. 16: 250-64. PMID 22883233 DOI: 10.1016/j.cmet.2012.07.007  1
2012 Dougherty JD, Zhang J, Feng H, Gong S, Heintz N. Mouse transgenesis in a single locus with independent regulation for multiple fluorophores. Plos One. 7: e40511. PMID 22808177 DOI: 10.1371/journal.pone.0040511  1
2012 Heller EA, Zhang W, Selimi F, Earnheart JC, ?limak MA, Santos-Torres J, Ibañez-Tallon I, Aoki C, Chait BT, Heintz N. The biochemical anatomy of cortical inhibitory synapses. Plos One. 7: e39572. PMID 22768092 DOI: 10.1371/journal.pone.0039572  1
2012 Chan CS, Peterson JD, Gertler TS, Glajch KE, Quintana RE, Cui Q, Sebel LE, Plotkin JL, Shen W, Heiman M, Heintz N, Greengard P, Surmeier DJ. Strain-specific regulation of striatal phenotype in Drd2-eGFP BAC transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9124-32. PMID 22764222 DOI: 10.1523/JNEUROSCI.0229-12.2012  1
2012 Newick K, Cunniff B, Preston K, Held P, Arbiser J, Pass H, Mossman B, Shukla A, Heintz N. Peroxiredoxin 3 is a redox-dependent target of thiostrepton in malignant mesothelioma cells. Plos One. 7: e39404. PMID 22761781 DOI: 10.1371/journal.pone.0039404  0.4
2012 Anathy V, Roberson E, Cunniff B, Nolin JD, Hoffman S, Spiess P, Guala AS, Lahue KG, Goldman D, Flemer S, van der Vliet A, Heintz NH, Budd RC, Tew KD, Janssen-Heininger YM. Oxidative processing of latent Fas in the endoplasmic reticulum controls the strength of apoptosis. Molecular and Cellular Biology. 32: 3464-78. PMID 22751926 DOI: 10.1128/MCB.00125-12  0.4
2012 Warner-Schmidt JL, Schmidt EF, Marshall JJ, Rubin AJ, Arango-Lievano M, Kaplitt MG, Ibañez-Tallon I, Heintz N, Greengard P. Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior. Proceedings of the National Academy of Sciences of the United States of America. 109: 11360-5. PMID 22733786 DOI: 10.1073/pnas.1209293109  1
2012 Tien AC, Tsai HH, Molofsky AV, McMahon M, Foo LC, Kaul A, Dougherty JD, Heintz N, Gutmann DH, Barres BA, Rowitch DH. Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord. Development (Cambridge, England). 139: 2477-87. PMID 22675209 DOI: 10.1242/dev.077214  1
2012 Schmidt EF, Warner-Schmidt JL, Otopalik BG, Pickett SB, Greengard P, Heintz N. Identification of the cortical neurons that mediate antidepressant responses. Cell. 149: 1152-63. PMID 22632977 DOI: 10.1016/j.cell.2012.03.038  1
2012 Walker BA, Hengst U, Kim HJ, Jeon NL, Schmidt EF, Heintz N, Milner TA, Jaffrey SR. Reprogramming axonal behavior by axon-specific viral transduction. Gene Therapy. 19: 947-55. PMID 22278412 DOI: 10.1038/gt.2011.217  1
2012 Tien AC, Tsai HH, Molofsky AV, McMahon M, Foo LC, Kaul A, Dougherty JD, Heintz N, Gutmann DH, Barres BA, Rowitch DH. Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord Journal of Cell Science. 125: 2477-2487.  1
2011 Li L, Rutlin M, Abraira VE, Cassidy C, Kus L, Gong S, Jankowski MP, Luo W, Heintz N, Koerber HR, Woodbury CJ, Ginty DD. The functional organization of cutaneous low-threshold mechanosensory neurons. Cell. 147: 1615-27. PMID 22196735 DOI: 10.1016/j.cell.2011.11.027  1
2011 Olson N, Hristova M, Heintz NH, Lounsbury KM, van der Vliet A. Activation of hypoxia-inducible factor-1 protects airway epithelium against oxidant-induced barrier dysfunction. American Journal of Physiology. Lung Cellular and Molecular Physiology. 301: L993-L1002. PMID 21926263 DOI: 10.1152/ajplung.00250.2011  0.4
2011 Luo Z, Volkow ND, Heintz N, Pan Y, Du C. Acute cocaine induces fast activation of D1 receptor and progressive deactivation of D2 receptor striatal neurons: in vivo optical microprobe [Ca2+]i imaging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 13180-90. PMID 21917801 DOI: 10.1523/JNEUROSCI.2369-11.2011  1
2011 Shukla A, Hillegass JM, MacPherson MB, Beuschel SL, Vacek PM, Butnor KJ, Pass HI, Carbone M, Testa JR, Heintz NH, Mossman BT. ERK2 is essential for the growth of human epithelioid malignant mesotheliomas. International Journal of Cancer. Journal International Du Cancer. 129: 1075-86. PMID 21710492 DOI: 10.1002/ijc.25763  0.4
2011 Yang Z, Jiang H, Chaichanasakul T, Gong S, Yang XW, Heintz N, Lin S. Corrigendum to " Modified bacterial artificial chromosomes for zebrafish transgenesis" Methods 39 (2006) 183-188 Methods. 53: 327. DOI: 10.1016/j.ymeth.2010.11.001  1
2010 Morishita H, Miwa JM, Heintz N, Hensch TK. Lynx1, a cholinergic brake, limits plasticity in adult visual cortex. Science (New York, N.Y.). 330: 1238-40. PMID 21071629 DOI: 10.1126/science.1195320  1
2010 Chao HT, Chen H, Samaco RC, Xue M, Chahrour M, Yoo J, Neul JL, Gong S, Lu HC, Heintz N, Ekker M, Rubenstein JL, Noebels JL, Rosenmund C, Zoghbi HY. Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes. Nature. 468: 263-9. PMID 21068835 DOI: 10.1038/nature09582  1
2010 Hyde SJ, Eckenroth BE, Smith BA, Eberley WA, Heintz NH, Jackman JE, Doublié S. tRNA(His) guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases. Proceedings of the National Academy of Sciences of the United States of America. 107: 20305-10. PMID 21059936 DOI: 10.1073/pnas.1010436107  0.4
2010 Borroto-Escuela DO, Romero-Fernandez W, Tarakanov AO, Gómez-Soler M, Corrales F, Marcellino D, Narvaez M, Frankowska M, Flajolet M, Heintz N, Agnati LF, Ciruela F, Fuxe K. Characterization of the A2AR-D2R interface: focus on the role of the C-terminal tail and the transmembrane helices. Biochemical and Biophysical Research Communications. 402: 801-7. PMID 21040702 DOI: 10.1016/j.bbrc.2010.10.122  1
2010 Gong S, Kus L, Heintz N. Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis. Nature Protocols. 5: 1678-96. PMID 20885380 DOI: 10.1038/nprot.2010.131  1
2010 Dougherty JD, Schmidt EF, Nakajima M, Heintz N. Analytical approaches to RNA profiling data for the identification of genes enriched in specific cells. Nucleic Acids Research. 38: 4218-30. PMID 20308160 DOI: 10.1093/nar/gkq130  1
2010 Borroto-Escuela DO, Marcellino D, Narvaez M, Flajolet M, Heintz N, Agnati L, Ciruela F, Fuxe K. A serine point mutation in the adenosine A2AR C-terminal tail reduces receptor heteromerization and allosteric modulation of the dopamine D2R. Biochemical and Biophysical Research Communications. 394: 222-7. PMID 20197060 DOI: 10.1016/j.bbrc.2010.02.168  1
2010 Heintz NH, Janssen-Heininger YM, Mossman BT. Asbestos, lung cancers, and mesotheliomas: from molecular approaches to targeting tumor survival pathways. American Journal of Respiratory Cell and Molecular Biology. 42: 133-9. PMID 20068227 DOI: 10.1165/rcmb.2009-0206TR  0.4
2010 Odell ID, Newick K, Heintz NH, Wallace SS, Pederson DS. Non-specific DNA binding interferes with the efficient excision of oxidative lesions from chromatin by the human DNA glycosylase, NEIL1. Dna Repair. 9: 134-43. PMID 20005182 DOI: 10.1016/j.dnarep.2009.11.005  0.4
2010 Groh A, Meyer HS, Schmidt EF, Heintz N, Sakmann B, Krieger P. Cell-type specific properties of pyramidal neurons in neocortex underlying a layout that is modifiable depending on the cortical area. Cerebral Cortex (New York, N.Y. : 1991). 20: 826-36. PMID 19643810 DOI: 10.1093/cercor/bhp152  1
2010 Odell ID, Newick K, Heintz NH, Wallace SS, Pederson DS. Corrigendum to "Non-specific DNA binding interferes with the efficient excision of oxidative lesions from chromatin by the human DNA glycosylase, NEIL1" [DNA Repair 9 (2010) 134-143] Dna Repair. 9: 938. DOI: 10.1016/j.dnarep.2010.02.007  0.4
2009 Haraldsen JD, Liu G, Botting CH, Walton JG, Storm J, Phalen TJ, Kwok LY, Soldati-Favre D, Heintz NH, Müller S, Westwood NJ, Ward GE. IDENTIFICATION OF CONOIDIN A AS A COVALENT INHIBITOR OF PEROXIREDOXIN II. Organic & Biomolecular Chemistry. 7: 3040-3048. PMID 21359112 DOI: 10.1039/B901735F  0.4
2009 Shukla A, Bosenberg MW, MacPherson MB, Butnor KJ, Heintz NH, Pass HI, Carbone M, Testa JR, Mossman BT. Activated cAMP response element binding protein is overexpressed in human mesotheliomas and inhibits apoptosis. The American Journal of Pathology. 175: 2197-206. PMID 19815709 DOI: 10.2353/ajpath.2009.090400  0.4
2009 Siegert S, Scherf BG, Del Punta K, Didkovsky N, Heintz N, Roska B. Genetic address book for retinal cell types. Nature Neuroscience. 12: 1197-204. PMID 19648912 DOI: 10.1038/nn.2370  1
2009 Burhans WC, Heintz NH. The cell cycle is a redox cycle: linking phase-specific targets to cell fate. Free Radical Biology & Medicine. 47: 1282-93. PMID 19486941 DOI: 10.1016/j.freeradbiomed.2009.05.026  0.4
2009 Selimi F, Cristea IM, Heller E, Chait BT, Heintz N. Proteomic studies of a single CNS synapse type: the parallel fiber/purkinje cell synapse. Plos Biology. 7: e83. PMID 19402746 DOI: 10.1371/journal.pbio.1000083  1
2009 Kriaucionis S, Heintz N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science (New York, N.Y.). 324: 929-30. PMID 19372393 DOI: 10.1126/science.1169786  1
2009 Zhong Y, Wang QJ, Li X, Yan Y, Backer JM, Chait BT, Heintz N, Yue Z. Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nature Cell Biology. 11: 468-76. PMID 19270693 DOI: 10.1038/ncb1854  1
2009 Tekinay AB, Nong Y, Miwa JM, Lieberam I, Ibanez-Tallon I, Greengard P, Heintz N. A role for LYNX2 in anxiety-related behavior. Proceedings of the National Academy of Sciences of the United States of America. 106: 4477-82. PMID 19246390 DOI: 10.1073/pnas.0813109106  1
2009 Heintz NH, Mossman BT. Molecular Responses to Asbestos: Induction of Cell Proliferation and Apoptosis Through Modulation of Redox-Dependent Cell Signaling Pathways Asbestos and Its Diseases. DOI: 10.1093/acprof:oso/9780195178692.003.0005  0.4
2009 Doyle JP, Dougherty JD, Heiman M, Schmidt EF, Stevens TR, Ma G, Bupp S, Shrestha P, Shah RD, Doughty ML, Gong S, Greengard P, Heintz N. Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types (DOI:10.1016/j.cell.2008.10.029) Cell. 139: 1022. DOI: 10.1016/j.cell.2009.11.011  1
2008 Chadman KK, Gong S, Scattoni ML, Boltuck SE, Gandhy SU, Heintz N, Crawley JN. Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice. Autism Research : Official Journal of the International Society For Autism Research. 1: 147-58. PMID 19360662 DOI: 10.1002/aur.22  1
2008 Doyle JP, Dougherty JD, Heiman M, Schmidt EF, Stevens TR, Ma G, Bupp S, Shrestha P, Shah RD, Doughty ML, Gong S, Greengard P, Heintz N. Application of a translational profiling approach for the comparative analysis of CNS cell types. Cell. 135: 749-62. PMID 19013282 DOI: 10.1016/j.cell.2008.10.029  1
2008 Heiman M, Schaefer A, Gong S, Peterson JD, Day M, Ramsey KE, Suárez-Fariñas M, Schwarz C, Stephan DA, Surmeier DJ, Greengard P, Heintz N. A translational profiling approach for the molecular characterization of CNS cell types. Cell. 135: 738-48. PMID 19013281 DOI: 10.1016/j.cell.2008.10.028  1
2008 Anthony TE, Heintz N. Genetic lineage tracing defines distinct neurogenic and gliogenic stages of ventral telencephalic radial glial development. Neural Development. 3: 30. PMID 18986511 DOI: 10.1186/1749-8104-3-30  1
2008 Drenan RM, Grady SR, Whiteaker P, McClure-Begley T, McKinney S, Miwa JM, Bupp S, Heintz N, McIntosh JM, Bencherif M, Marks MJ, Lester HA. In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors. Neuron. 60: 123-36. PMID 18940593 DOI: 10.1016/j.neuron.2008.09.009  1
2008 Nishi A, Kuroiwa M, Miller DB, O'Callaghan JP, Bateup HS, Shuto T, Sotogaku N, Fukuda T, Heintz N, Greengard P, Snyder GL. Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10460-71. PMID 18923023 DOI: 10.1523/JNEUROSCI.2518-08.2008  1
2008 Bateup HS, Svenningsson P, Kuroiwa M, Gong S, Nishi A, Heintz N, Greengard P. Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs. Nature Neuroscience. 11: 932-9. PMID 18622401 DOI: 10.1038/nn.2153  1
2008 Janssen-Heininger YM, Mossman BT, Heintz NH, Forman HJ, Kalyanaraman B, Finkel T, Stamler JS, Rhee SG, van der Vliet A. Redox-based regulation of signal transduction: principles, pitfalls, and promises. Free Radical Biology & Medicine. 45: 1-17. PMID 18423411 DOI: 10.1016/j.freeradbiomed.2008.03.011  0.4
2007 Phelps SF, Illenye S, Heintz NH. Manipulating genes and gene copy number by bacterial artificial chromosomes transfection. Methods in Molecular Biology (Clifton, N.J.). 383: 153-63. PMID 18217684  0.4
2007 Gong S, Doughty M, Harbaugh CR, Cummins A, Hatten ME, Heintz N, Gerfen CR. Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9817-23. PMID 17855595 DOI: 10.1523/JNEUROSCI.2707-07.2007  1
2007 Gorokhova S, Bibert S, Geering K, Heintz N. A novel family of transmembrane proteins interacting with beta subunits of the Na,K-ATPase. Human Molecular Genetics. 16: 2394-410. PMID 17606467 DOI: 10.1093/hmg/ddm167  1
2007 Muss HB, Bunn JY, Crocker A, Plaut K, Koh J, Heintz N, Rincon M, Weaver DL, Tam D, Beatty B, Kaufman P, Donovan M, Verbel D, Weiss L. Cyclin D-1, interleukin-6, HER-2/neu, transforming growth factor receptor-II and prediction of relapse in women with early stage, hormone receptor-positive breast cancer treated with tamoxifen. The Breast Journal. 13: 337-45. PMID 17593037 DOI: 10.1111/j.1524-4741.2007.00440.x  0.4
2007 Head K, Gong S, Joseph S, Wang C, Burkhardt T, Rossi MR, LaDuca J, Matsui S, Vaughan M, Hicks DG, Heintz N, Cowell JK. Defining the expression pattern of the LGI1 gene in BAC transgenic mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 328-37. PMID 17565425 DOI: 10.1007/s00335-007-9024-6  1
2007 Chang SY, Zagha E, Kwon ES, Ozaita A, Bobik M, Martone ME, Ellisman MH, Heintz N, Rudy B. Distribution of Kv3.3 potassium channel subunits in distinct neuronal populations of mouse brain. The Journal of Comparative Neurology. 502: 953-72. PMID 17444489 DOI: 10.1002/cne.21353  1
2007 Anthony TE, Heintz N. The folate metabolic enzyme ALDH1L1 is restricted to the midline of the early CNS, suggesting a role in human neural tube defects. The Journal of Comparative Neurology. 500: 368-83. PMID 17111379 DOI: 10.1002/cne.21179  1
2007 Pantano C, Anathy V, Ranjan P, Heintz NH, Janssen-Heininger YM. Nonphagocytic oxidase 1 causes death in lung epithelial cells via a TNF-RI-JNK signaling axis. American Journal of Respiratory Cell and Molecular Biology. 36: 473-9. PMID 17079781 DOI: 10.1165/rcmb.2006-0109OC  0.4
2006 Phalen TJ, Weirather K, Deming PB, Anathy V, Howe AK, van der Vliet A, Jönsson TJ, Poole LB, Heintz NH. Oxidation state governs structural transitions in peroxiredoxin II that correlate with cell cycle arrest and recovery. The Journal of Cell Biology. 175: 779-89. PMID 17145963 DOI: 10.1083/jcb.200606005  0.4
2006 Ranjan P, Anathy V, Burch PM, Weirather K, Lambeth JD, Heintz NH. Redox-dependent expression of cyclin D1 and cell proliferation by Nox1 in mouse lung epithelial cells. Antioxidants & Redox Signaling. 8: 1447-59. PMID 16987002 DOI: 10.1089/ars.2006.8.1447  0.4
2006 Miwa JM, Stevens TR, King SL, Caldarone BJ, Ibanez-Tallon I, Xiao C, Fitzsimonds RM, Pavlides C, Lester HA, Picciotto MR, Heintz N. The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo. Neuron. 51: 587-600. PMID 16950157 DOI: 10.1016/j.neuron.2006.07.025  1
2006 Reynaert NL, van der Vliet A, Guala AS, McGovern T, Hristova M, Pantano C, Heintz NH, Heim J, Ho YS, Matthews DE, Wouters EF, Janssen-Heininger YM. Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta. Proceedings of the National Academy of Sciences of the United States of America. 103: 13086-91. PMID 16916935 DOI: 10.1073/pnas.0603290103  0.4
2006 Wang QJ, Ding Y, Kohtz DS, Kohtz S, Mizushima N, Cristea IM, Rout MP, Chait BT, Zhong Y, Heintz N, Yue Z. Induction of autophagy in axonal dystrophy and degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8057-68. PMID 16885219 DOI: 10.1523/JNEUROSCI.2261-06.2006  1
2006 Yang Z, Jiang H, Chaichanasakul T, Chachainasakul T, Gong S, Yang XW, Heintz N, Lin S. Modified bacterial artificial chromosomes for zebrafish transgenesis. Methods (San Diego, Calif.). 39: 183-8. PMID 16828309 DOI: 10.1016/j.ymeth.2006.04.011  1
2006 Ranjan P, Heintz NH. S-phase arrest by reactive nitrogen species is bypassed by okadaic acid, an inhibitor of protein phosphatases PP1/PP2A. Free Radical Biology & Medicine. 40: 247-59. PMID 16413407 DOI: 10.1016/j.freeradbiomed.2005.08.049  0.4
2006 Poynter ME, Persinger RL, Irvin CG, Butnor KJ, van Hirtum H, Blay W, Heintz NH, Robbins J, Hemenway D, Taatjes DJ, Janssen-Heininger Y. Nitrogen dioxide enhances allergic airway inflammation and hyperresponsiveness in the mouse. American Journal of Physiology. Lung Cellular and Molecular Physiology. 290: L144-52. PMID 16085673 DOI: 10.1152/ajplung.00131.2005  0.4
2005 Rubinsztein DC, DiFiglia M, Heintz N, Nixon RA, Qin ZH, Ravikumar B, Stefanis L, Tolkovsky A. Autophagy and its possible roles in nervous system diseases, damage and repair. Autophagy. 1: 11-22. PMID 16874045  1
2005 Haegens A, van der Vliet A, Butnor KJ, Heintz N, Taatjes D, Hemenway D, Vacek P, Freeman BA, Hazen SL, Brennan ML, Mossman BT. Asbestos-induced lung inflammation and epithelial cell proliferation are altered in myeloperoxidase-null mice. Cancer Research. 65: 9670-7. PMID 16266986 DOI: 10.1158/0008-5472.CAN-05-1751  0.4
2005 Selimi F, Heintz N. How neurons keep in touch. Nature Neuroscience. 8: 1417-8. PMID 16251974 DOI: 10.1038/nn1105-1417  1
2005 Sabo-Attwood T, Ramos-Nino M, Bond J, Butnor KJ, Heintz N, Gruber AD, Steele C, Taatjes DJ, Vacek P, Mossman BT. Gene expression profiles reveal increased mClca3 (Gob5) expression and mucin production in a murine model of asbestos-induced fibrogenesis. The American Journal of Pathology. 167: 1243-56. PMID 16251409 DOI: 10.1016/S0002-9440(10)61212-6  0.4
2005 Hatten ME, Heintz N. Large-scale genomic approaches to brain development and circuitry. Annual Review of Neuroscience. 28: 89-108. PMID 16022591 DOI: 10.1146/annurev.neuro.26.041002.131436  1
2005 Ramos-Nino ME, Vianale G, Sabo-Attwood T, Mutti L, Porta C, Heintz N, Mossman BT. Human mesothelioma cells exhibit tumor cell-specific differences in phosphatidylinositol 3-kinase/AKT activity that predict the efficacy of Onconase. Molecular Cancer Therapeutics. 4: 835-42. PMID 15897248 DOI: 10.1158/1535-7163.MCT-04-0243  0.4
2005 Burch PM, Heintz NH. Redox regulation of cell-cycle re-entry: cyclin D1 as a primary target for the mitogenic effects of reactive oxygen and nitrogen species. Antioxidants & Redox Signaling. 7: 741-51. PMID 15890020 DOI: 10.1089/ars.2005.7.741  0.4
2005 Gu X, Li C, Wei W, Lo V, Gong S, Li SH, Iwasato T, Itohara S, Li XJ, Mody I, Heintz N, Yang XW. Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice. Neuron. 46: 433-44. PMID 15882643 DOI: 10.1016/j.neuron.2005.03.025  1
2005 Anthony TE, Heintz N. Cre-ating somatic cell genetic mosaics in the mouse. Cell. 121: 322-3. PMID 15882615 DOI: 10.1016/j.cell.2005.04.019  1
2005 Anthony TE, Mason HA, Gridley T, Fishell G, Heintz N. Brain lipid-binding protein is a direct target of Notch signaling in radial glial cells. Genes & Development. 19: 1028-33. PMID 15879553 DOI: 10.1101/gad.1302105  1
2005 Rice TS, Ding M, Pederson DS, Heintz NH. The highly conserved tRNAHis guanylyltransferase Thg1p interacts with the origin recognition complex and is required for the G2/M phase transition in the yeast Saccharomyces cerevisiae. Eukaryotic Cell. 4: 832-5. PMID 15821142 DOI: 10.1128/EC.4.4.832-835.2005  0.4
2004 Heintz N. Developmental biology: survival by self-digestion. Nature. 432: 963. PMID 15616545 DOI: 10.1038/432963a  1
2004 Yuan Z, Taatjes DJ, Mossman BT, Heintz NH. The duration of nuclear extracellular signal-regulated kinase 1 and 2 signaling during cell cycle reentry distinguishes proliferation from apoptosis in response to asbestos. Cancer Research. 64: 6530-6. PMID 15374964 DOI: 10.1158/0008-5472.CAN-04-0946  0.4
2004 Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, et al. The knockout mouse project. Nature Genetics. 36: 921-4. PMID 15340423 DOI: 10.1038/ng0904-921  1
2004 Ibañez-Tallon I, Wen H, Miwa JM, Xing J, Tekinay AB, Ono F, Brehm P, Heintz N. Tethering naturally occurring peptide toxins for cell-autonomous modulation of ion channels and receptors in vivo. Neuron. 43: 305-11. PMID 15294139 DOI: 10.1016/j.neuron.2004.07.015  1
2004 Ibañez-Tallon I, Pagenstecher A, Fliegauf M, Olbrich H, Kispert A, Ketelsen UP, North A, Heintz N, Omran H. Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation. Human Molecular Genetics. 13: 2133-41. PMID 15269178 DOI: 10.1093/hmg/ddh219  1
2004 Ranjan P, Shrivastava P, Singh SM, Sodhi A, Heintz NH. Baculovirus P35 inhibits NO-induced apoptosis in activated macrophages by inhibiting cytochrome c release. Journal of Cell Science. 117: 3031-9. PMID 15173317 DOI: 10.1242/jcs.01121  0.4
2004 Schroll AL, Heintz NH. Chemical footprinting of structural and functional elements of dhfr oribeta during the CHOC 400 cell cycle. Gene. 332: 139-47. PMID 15145063 DOI: 10.1016/j.gene.2004.02.032  0.4
2004 Burch PM, Yuan Z, Loonen A, Heintz NH. An extracellular signal-regulated kinase 1- and 2-dependent program of chromatin trafficking of c-Fos and Fra-1 is required for cyclin D1 expression during cell cycle reentry. Molecular and Cellular Biology. 24: 4696-709. PMID 15143165 DOI: 10.1128/MCB.24.11.4696-4709.2004  0.4
2004 Heintz N. Gene expression nervous system atlas (GENSAT). Nature Neuroscience. 7: 483. PMID 15114362 DOI: 10.1038/nn0504-483  1
2004 Anthony TE, Klein C, Fishell G, Heintz N. Radial glia serve as neuronal progenitors in all regions of the central nervous system. Neuron. 41: 881-90. PMID 15046721 DOI: 10.1016/S0896-6273(04)00140-0  1
2004 Espinosa F, Marks G, Heintz N, Joho RH. Increased motor drive and sleep loss in mice lacking Kv3-type potassium channels. Genes, Brain, and Behavior. 3: 90-100. PMID 15005717 DOI: 10.1046/j.1601-183x.2003.00054.x  1
2004 Illenye S, Heintz NH. Functional analysis of bacterial artificial chromosomes in mammalian cells: mouse Cdc6 is associated with the mitotic spindle apparatus. Genomics. 83: 66-75. PMID 14667810 DOI: 10.1016/S0888-7543(03)00205-2  0.4
2003 Yue Z, Jin S, Yang C, Levine AJ, Heintz N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proceedings of the National Academy of Sciences of the United States of America. 100: 15077-82. PMID 14657337 DOI: 10.1073/pnas.2436255100  1
2003 Gong S, Zheng C, Doughty ML, Losos K, Didkovsky N, Schambra UB, Nowak NJ, Joyner A, Leblanc G, Hatten ME, Heintz N. A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature. 425: 917-25. PMID 14586460 DOI: 10.1038/nature02033  1
2003 Montigny WJ, Phelps SF, Illenye S, Heintz NH. Parameters influencing high-efficiency transfection of bacterial artificial chromosomes into cultured mammalian cells. Biotechniques. 35: 796-807. PMID 14579745  0.4
2003 Ramos-Nino ME, Heintz N, Scappoli L, Martinelli M, Land S, Nowak N, Haegens A, Manning B, Manning N, MacPherson M, Stern M, Mossman B. Gene profiling and kinase screening in asbestos-exposed epithelial cells and lungs. American Journal of Respiratory Cell and Molecular Biology. 29: S51-8. PMID 14503555  0.4
2003 Park KK, Deok Ahn J, Lee IK, Magae J, Heintz NH, Kwak JY, Lee YC, Cho YS, Kim HC, Chae YM, Ho Kim Y, Kim CH, Chang YC. Inhibitory effects of novel E2F decoy oligodeoxynucleotides on mesangial cell proliferation by coexpression of E2F/DP. Biochemical and Biophysical Research Communications. 308: 689-97. PMID 12927774 DOI: 10.1016/S0006-291X(03)01455-4  0.4
2003 Heintz N. Biomedicine. Ataxin-1 regulators in the spotlight. Science (New York, N.Y.). 301: 59-60. PMID 12843383 DOI: 10.1126/science.1086311  1
2003 Ibañez-Tallon I, Heintz N, Omran H. To beat or not to beat: roles of cilia in development and disease. Human Molecular Genetics. 12: R27-35. PMID 12668594  1
2003 Yuan Z, Schellekens H, Warner L, Janssen-Heininger Y, Burch P, Heintz NH. Reactive nitrogen species block cell cycle re-entry through sustained production of hydrogen peroxide. American Journal of Respiratory Cell and Molecular Biology. 28: 705-12. PMID 12600834 DOI: 10.1165/rcmb.2002-0112OC  0.4
2002 Gong S, Yang XW, Li C, Heintz N. Highly efficient modification of bacterial artificial chromosomes (BACs) using novel shuttle vectors containing the R6Kgamma origin of replication. Genome Research. 12: 1992-8. PMID 12466304 DOI: 10.1101/gr.476202  1
2002 Yue Z, Horton A, Bravin M, DeJager PL, Selimi F, Heintz N. A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice. Neuron. 35: 921-33. PMID 12372286 DOI: 10.1016/S0896-6273(02)00861-9  1
2002 Zhu W, Rainville IR, Ding M, Bolus M, Heintz NH, Pederson DS. Evidence that the pre-mRNA splicing factor Clf1p plays a role in DNA replication in Saccharomyces cerevisiae. Genetics. 160: 1319-33. PMID 11973290  0.4
2002 Ibañez-Tallon I, Gorokhova S, Heintz N. Loss of function of axonemal dynein Mdnah5 causes primary ciliary dyskinesia and hydrocephalus. Human Molecular Genetics. 11: 715-21. PMID 11912187  1
2002 Ibañez-Tallon I, Miwa JM, Wang HL, Adams NC, Crabtree GW, Sine SM, Heintz N. Novel modulation of neuronal nicotinic acetylcholine receptors by association with the endogenous prototoxin lynx1. Neuron. 33: 893-903. PMID 11906696 DOI: 10.1016/S0896-6273(02)00632-3  1
2001 Heintz N. BAC to the future: the use of bac transgenic mice for neuroscience research. Nature Reviews. Neuroscience. 2: 861-70. PMID 11733793 DOI: 10.1038/35104049  1
2001 Misulovin Z, Yang XW, Yu W, Heintz N, Meffre E. A rapid method for targeted modification and screening of recombinant bacterial artificial chromosome. Journal of Immunological Methods. 257: 99-105. PMID 11687243 DOI: 10.1016/S0022-1759(01)00452-5  1
2001 Espinosa F, McMahon A, Chan E, Wang S, Ho CS, Heintz N, Joho RH. Alcohol hypersensitivity, increased locomotion, and spontaneous myoclonus in mice lacking the potassium channels Kv3.1 and Kv3.3. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 6657-65. PMID 11517255  1
2001 Persinger RL, Blay WM, Heintz NH, Hemenway DR, Janssen-Heininger YM. Nitrogen dioxide induces death in lung epithelial cells in a density-dependent manner. American Journal of Respiratory Cell and Molecular Biology. 24: 583-90. PMID 11350828 DOI: 10.1165/ajrcmb.24.5.4340  0.4
2001 Montigny WJ, Houchens CR, Illenye S, Gilbert J, Coonrod E, Chang YC, Heintz NH. Condensation by DNA looping facilitates transfer of large DNA molecules into mammalian cells. Nucleic Acids Research. 29: 1982-8. PMID 11328883 DOI: 10.1093/nar/29.9.1982  0.4
2001 Chang YC, Illenye S, Heintz NH. Cooperation of E2F-p130 and Sp1-pRb complexes in repression of the Chinese hamster dhfr gene. Molecular and Cellular Biology. 21: 1121-31. PMID 11158299 DOI: 10.1128/MCB.21.4.1121-1131.2001  0.4
2000 Chang YC, Nakajima H, Illenye S, Lee YS, Honjo N, Makiyama T, Fujiwara I, Mizuta N, Sawai K, Saida K, Mitsui Y, Heintz NH, Magae J. Caspase-dependent apoptosis by ectopic expression of E2F-4. Oncogene. 19: 4713-20. PMID 11032021 DOI: 10.1038/sj.onc.1203833  0.4
2000 Wollmuth LP, Kuner T, Jatzke C, Seeburg PH, Heintz N, Zuo J. The Lurcher mutation identifies delta 2 as an AMPA/kainate receptor-like channel that is potentiated by Ca(2+). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5973-80. PMID 10934245  1
2000 Heintz N. One-hit neuronal death. Nature. 406: 137, 139. PMID 10910338 DOI: 10.1038/35018196  1
2000 Heintz N, Zoghbi HY. Insights from mouse models into the molecular basis of neurodegeneration. Annual Review of Physiology. 62: 779-802. PMID 10845111 DOI: 10.1146/annurev.physiol.62.1.779  1
2000 Doughty ML, De Jager PL, Korsmeyer SJ, Heintz N. Neurodegeneration in Lurcher mice occurs via multiple cell death pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3687-94. PMID 10804210  1
2000 Heintz N. Analysis of mammalian central nervous system gene expression and function using bacterial artificial chromosome-mediated transgenesis. Human Molecular Genetics. 9: 937-43. PMID 10767317  1
2000 Geraghty DS, Ding M, Heintz NH, Pederson DS. Premature structural changes at replication origins in a yeast minichromosome maintenance (MCM) mutant. The Journal of Biological Chemistry. 275: 18011-21. PMID 10751424 DOI: 10.1074/jbc.M909787199  0.4
2000 Houchens CR, Montigny W, Zeltser L, Dailey L, Gilbert JM, Heintz NH. The dhfr oribeta-binding protein RIP60 contains 15 zinc fingers: DNA binding and looping by the central three fingers and an associated proline-rich region. Nucleic Acids Research. 28: 570-81. PMID 10606657  0.44
2000 Houchens CR, Montigny W, Zeltser L, Dailey L, Gilbert JM, Heintz NM. The dhfr oriβ-binding protein RIP60 contains 15 zinc fingers: DNA binding and looping by the central three fingers and an associated proline-rich region Nucleic Acids Research. 28: 570-581.  1
1999 Yang XW, Wynder C, Doughty ML, Heintz N. BAC-mediated gene-dosage analysis reveals a role for Zipro1 (Ru49/Zfp38) in progenitor cell proliferation in cerebellum and skin. Nature Genetics. 22: 327-35. PMID 10431235 DOI: 10.1038/11896  1
1999 Heintz N, De Jager PL. GluR delta 2 and the development and death of cerebellar Purkinje neurons in lurcher mice. Annals of the New York Academy of Sciences. 868: 502-14. PMID 10414327 DOI: 10.1111/j.1749-6632.1999.tb11319.x  1
1999 Miwa JM, Ibanez-Tallon I, Crabtree GW, Sánchez R, Sali A, Role LW, Heintz N. lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS. Neuron. 23: 105-14. PMID 10402197 DOI: 10.1016/S0896-6273(00)80757-6  1
1999 Magae J, Illenye S, Chang YC, Mitsui Y, Heintz NH. Association with E2F-1 governs intracellular trafficking and polyubiquitination of DP-1. Oncogene. 18: 593-605. PMID 9989809 DOI: 10.1038/sj.onc.1202345  0.4
1998 De Jager PL, Heintz N. The lurcher mutation and ionotropic glutamate receptors: contributions to programmed neuronal death in vivo. Brain Pathology (Zurich, Switzerland). 8: 795-807. PMID 9804384  1
1998 Gubbay J, Doyle JP, Skinner M, Heintz N. Changing patterns of gene expression identify multiple steps during regression of rat prostate in vivo. Endocrinology. 139: 2935-43. PMID 9607804 DOI: 10.1210/endo.139.6.6075  1
1998 De Jager PL, Harvey D, Polydorides AD, Zuo J, Heintz N. A high-resolution genetic map of the nervous locus on mouse chromosome 8. Genomics. 48: 346-53. PMID 9545640 DOI: 10.1006/geno.1997.5193  1
1998 Hu W, Zuo J, De Jager PL, Heintz N. The human glutamate receptor delta 2 gene (GRID2) maps to chromosome 4q22. Genomics. 47: 143-5. PMID 9465309 DOI: 10.1006/geno.1997.5108  1
1998 Chang YC, Lee YS, Tejima T, Tanaka K, Omura S, Heintz NH, Mitsui Y, Magae J. mdm2 and bax, downstream mediators of the p53 response, are degraded by the ubiquitin-proteasome pathway. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 9: 79-84. PMID 9438391  0.4
1997 Heintz NH. Phosphorylation of proteins that regulate the cell cycle and cancer: an international perspective. Japanese Journal of Clinical Oncology. 27: 288. PMID 9379522  0.4
1997 Yang XW, Model P, Heintz N. Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome. Nature Biotechnology. 15: 859-65. PMID 9306400 DOI: 10.1038/nbt0997-859  1
1997 Rousselot P, Heintz N, Nottebohm F. Expression of brain lipid binding protein in the brain of the adult canary and its implications for adult neurogenesis. The Journal of Comparative Neurology. 385: 415-26. PMID 9300768 DOI: 10.1002/(SICI)1096-9861(19970901)385:3<415::AID-CNE6>3.0.CO;2-6  1
1997 Zuo J, De Jager PL, Takahashi KA, Jiang W, Linden DJ, Heintz N. Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene. Nature. 388: 769-73. PMID 9285588 DOI: 10.1038/42009  1
1997 De Jager PL, Zuo J, Cook SA, Heintz N. A new allele of the lurcher gene, lurcherJ. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 8: 647-50. PMID 9271665 DOI: 10.1007/s003359900530  1
1997 Magae J, Illenye S, Tejima T, Chang YC, Mitsui Y, Tanaka K, Omura S, Heintz NH. Transcriptional squelching by ectopic expression of E2F-1 and p53 is alleviated by proteasome inhibitors MG-132 and lactacystin. Oncogene. 15: 759-69. PMID 9266962 DOI: 10.1038/sj.onc.1201251  0.4
1997 De Jager PL, Zuo J, Heintz N. An approximately 1.2-Mb bacterial artificial chromosome contig refines the genetic and physical maps of the lurcher locus on mouse chromosome 6. Genome Research. 7: 736-46. PMID 9253602 DOI: 10.1101/GR.7.7.736  1
1997 Fung H, Quinlan TR, Janssen YM, Timblin CR, Marsh JP, Heintz NH, Taatjes DJ, Vacek P, Jaken S, Mossman BT. Inhibition of protein kinase C prevents asbestos-induced c-fos and c-jun proto-oncogene expression in mesothelial cells. Cancer Research. 57: 3101-5. PMID 9242432  0.4
1997 Heintz N, Zoghbi H. alpha-Synuclein--a link between Parkinson and Alzheimer diseases? Nature Genetics. 16: 325-7. PMID 9241262 DOI: 10.1038/ng0897-325  1
1997 Arnold DB, Heintz N. A calcium responsive element that regulates expression of two calcium binding proteins in Purkinje cells. Proceedings of the National Academy of Sciences of the United States of America. 94: 8842-7. PMID 9238065 DOI: 10.1073/pnas.94.16.8842  1
1997 Cheng SS, Heintz N. Massive loss of mid- and hindbrain neurons during embryonic development of homozygous lurcher mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 2400-7. PMID 9065501  1
1997 Hatten ME, Alder J, Zimmerman K, Heintz N. Genes involved in cerebellar cell specification and differentiation. Current Opinion in Neurobiology. 7: 40-7. PMID 9039803 DOI: 10.1016/S0959-4388(97)80118-3  1
1997 Wells JM, Illenye S, Magae J, Wu CL, Heintz NH. Accumulation of E2F-4.DP-1 DNA binding complexes correlates with induction of dhfr gene expression during the G1 to S phase transition. The Journal of Biological Chemistry. 272: 4483-92. PMID 9020173 DOI: 10.1074/jbc.272.7.4483  0.4
1996 Segil N, Guermah M, Hoffmann A, Roeder RG, Heintz N. Mitotic regulation of TFIID: inhibition of activator-dependent transcription and changes in subcellular localization. Genes & Development. 10: 2389-400. PMID 8843192  1
1996 Magae J, Wu CL, Illenye S, Harlow E, Heintz NH. Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members. Journal of Cell Science. 109: 1717-26. PMID 8832394  0.4
1996 Mossman BT, Surinrut P, Brinton BT, Marsh JP, Heintz NH, Lindau-Shepard B, Shaffer JB. Transfection of a manganese-containing superoxide dismutase gene into hamster tracheal epithelial cells ameliorates asbestos-mediated cytotoxicity. Free Radical Biology & Medicine. 21: 125-31. PMID 8818626 DOI: 10.1016/0891-5849(96)00014-7  0.4
1996 Xu LZ, Sánchez R, Sali A, Heintz N. Ligand specificity of brain lipid-binding protein. The Journal of Biological Chemistry. 271: 24711-9. PMID 8798739 DOI: 10.1074/jbc.271.40.24711  1
1996 Heintz N. Ataxia telangiectasia: cell signaling, cell death and the cell cycle. Current Opinion in Neurology. 9: 137-40. PMID 8782982  1
1996 Zeltser L, Desplan C, Heintz N. Hoxb-13: a new Hox gene in a distant region of the HOXB cluster maintains colinearity. Development (Cambridge, England). 122: 2475-84. PMID 8756292  1
1996 Yang XW, Zhong R, Heintz N. Granule cell specification in the developing mouse brain as defined by expression of the zinc finger transcription factor RU49. Development (Cambridge, England). 122: 555-66. PMID 8625807  1
1996 Zheng C, Heintz N, Hatten ME. CNS gene encoding astrotactin, which supports neuronal migration along glial fibers. Science (New York, N.Y.). 272: 417-9. PMID 8602532  1
1996 Wells J, Held P, Illenye S, Heintz NH. Protein-DNA interactions at the major and minor promoters of the divergently transcribed dhfr and rep3 genes during the Chinese hamster ovary cell cycle. Molecular and Cellular Biology. 16: 634-47. PMID 8552092  0.4
1995 Zuo J, De Jager PL, Norman DJ, Heintz N. Generation of a high-resolution genetic map and a YAC contig of the Lurcher locus on mouse chromosome 6. Genome Research. 5: 381-92. PMID 8750197  1
1995 Brinton BT, Heintz NH. Plasmid amplification-promoting sequences from the origin region of Chinese hamster dihydrofolate reductase gene do not promote position-independent chromosomal gene amplification. Chromosoma. 104: 143-51. PMID 8585992 DOI: 10.1007/BF00347697  0.4
1995 Norman DJ, Feng L, Cheng SS, Gubbay J, Chan E, Heintz N. The lurcher gene induces apoptotic death in cerebellar Purkinje cells. Development (Cambridge, England). 121: 1183-93. PMID 7743930  1
1995 Janssen YM, Heintz NH, Mossman BT. Induction of c-fos and c-jun proto-oncogene expression by asbestos is ameliorated by N-acetyl-L-cysteine in mesothelial cells. Cancer Research. 55: 2085-9. PMID 7743507  0.4
1995 Hatten ME, Heintz N. Mechanisms of neural patterning and specification in the developing cerebellum. Annual Review of Neuroscience. 18: 385-408. PMID 7605067 DOI: 10.1146/annurev.ne.18.030195.002125  1
1995 Feng L, Heintz N. Differentiating neurons activate transcription of the brain lipid-binding protein gene in radial glia through a novel regulatory element. Development (Cambridge, England). 121: 1719-30. PMID 7600988  1
1994 Goldman-Wohl DS, Chan E, Baird D, Heintz N. Kv3.3b: a novel Shaw type potassium channel expressed in terminally differentiated cerebellar Purkinje cells and deep cerebellar nuclei. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 511-22. PMID 8301351  1
1994 Feng L, Hatten ME, Heintz N. Brain lipid-binding protein (BLBP): a novel signaling system in the developing mammalian CNS. Neuron. 12: 895-908. PMID 8161459 DOI: 10.1016/0896-6273(94)90341-7  1
1994 Martinelli R, Heintz N. H1TF2A, the large subunit of a heterodimeric, glutamine-rich CCAAT-binding transcription factor involved in histone H1 cell cycle regulation. Molecular and Cellular Biology. 14: 8322-32. PMID 7969168  1
1994 Janssen YM, Heintz NH, Marsh JP, Borm PJ, Mossman BT. Induction of c-fos and c-jun proto-oncogenes in target cells of the lung and pleura by carcinogenic fibers. American Journal of Respiratory Cell and Molecular Biology. 11: 522-30. PMID 7946382 DOI: 10.1165/ajrcmb.11.5.7946382  0.4
1994 Arnold D, Feng L, Kim J, Heintz N. A strategy for the analysis of gene expression during neural development. Proceedings of the National Academy of Sciences of the United States of America. 91: 9970-4. PMID 7937928 DOI: 10.1073/pnas.91.21.9970  1
1994 Held PG, Absher M, Heintz NH, Hale PD. Automated procedures for the quantitation of protein. Biotechniques. 17: 988-91. PMID 7840981  0.4
1994 Heintz N. Future trends affecting the lab: The life scientist's view Annals of the New York Academy of Sciences. 735: 10-14. DOI: 10.1111/j.1749-6632.1994.tb31017.x  1
1994 Baird DH, Hatten ME, Heintz N, Mason CA. Micromethods for Analyzing Axon-Target Interactions in Vitro Neuroprotocols. 4: 106-115. DOI: 10.1006/ncmn.1994.1013  1
1993 McKinney JD, Chang F, Heintz N, Cross FR. Negative regulation of FAR1 at the Start of the yeast cell cycle. Genes & Development. 7: 833-43. PMID 8491380  1
1993 Lee KR, Howard P, Heintz NH, Collins CC. Low prevalence of human papillomavirus types 16 and 18 in cervical adenocarcinoma in situ, invasive adenocarcinoma, and glandular dysplasia by polymerase chain reaction. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 6: 433-7. PMID 8415587  0.4
1993 Heintz NH, Janssen YM, Mossman BT. Persistent induction of c-fos and c-jun expression by asbestos. Proceedings of the National Academy of Sciences of the United States of America. 90: 3299-303. PMID 8386370  0.4
1993 Mastrangelo IA, Held PG, Dailey L, Wall JS, Hough PV, Heintz N, Heintz NH. RIP60 dimers and multiples of dimers assemble link structures at an origin of bidirectional replication in the dihydrofolate reductase amplicon of Chinese hamster ovary cells. Journal of Molecular Biology. 232: 766-78. PMID 8355269 DOI: 10.1006/jmbi.1993.1430  0.44
1993 Heintz N. Cell death and the cell cycle: a relationship between transformation and neurodegeneration? Trends in Biochemical Sciences. 18: 157-9. PMID 8328013 DOI: 10.1016/0968-0004(93)90103-T  1
1993 Kuhar SG, Feng L, Vidan S, Ross ME, Hatten ME, Heintz N. Changing patterns of gene expression define four stages of cerebellar granule neuron differentiation. Development (Cambridge, England). 117: 97-104. PMID 8223263  1
1992 Held PG, Heintz NH. Eukaryotic replication origins. Biochimica Et Biophysica Acta. 1130: 235-46. PMID 1562602 DOI: 10.1016/0167-4781(92)90435-3  0.4
1992 Heintz NH. Transcription factors and the control of DNA replication. Current Opinion in Cell Biology. 4: 459-67. PMID 1497917 DOI: 10.1016/0955-0674(92)90012-2  0.4
1992 Heintz NH, Dailey L, Held P, Heintz N. Eukaryotic replication origins as promoters of bidirectional DNA synthesis. Trends in Genetics : Tig. 8: 376-81. PMID 1440873 DOI: 10.1016/0168-9525(92)90298-I  0.4
1991 Fletcher C, Norman DJ, Germond E, Heintz N. A multilocus linkage map of mouse chromosome 8. Genomics. 9: 737-41. PMID 2037298 DOI: 10.1016/0888-7543(91)90368-O  1
1991 Fletcher C, Norman DJ, Heintz N. Genetic mapping of meander tail, a mouse mutation affecting cerebellar development. Genomics. 9: 647-55. PMID 2037292 DOI: 10.1016/0888-7543(91)90358-L  1
1991 Gao WO, Heintz N, Hatten ME. Cerebellar granule cell neurogenesis is regulated by cell-cell interactions in vitro. Neuron. 6: 705-15. PMID 2025426 DOI: 10.1016/0896-6273(91)90168-Y  1
1991 Heintz N. The regulation of histone gene expression during the cell cycle. Biochimica Et Biophysica Acta. 1088: 327-39. PMID 2015297 DOI: 10.1016/0167-4781(91)90122-3  1
1991 La Bella F, Heintz N. Histone gene transcription factor binding in extracts of normal human cells. Molecular and Cellular Biology. 11: 5825-31. PMID 1944265  1
1991 Roberts SB, Segil N, Heintz N. Differential phosphorylation of the transcription factor Oct1 during the cell cycle. Science (New York, N.Y.). 253: 1022-6. PMID 1887216  1
1991 Brinton BT, Caddle MS, Heintz NH. Position and orientation-dependent effects of a eukaryotic Z-triplex DNA motif on episomal DNA replication in COS-7 cells. The Journal of Biological Chemistry. 266: 5153-61. PMID 1848241  0.4
1991 Segil N, Roberts SB, Heintz N. Cell-cycle-regulated phosphorylation of the transcription factor Oct-1. Cold Spring Harbor Symposia On Quantitative Biology. 56: 285-92. PMID 1819493  1
1991 Ovnic M, Swank RT, Fletcher C, Zhen L, Novak EK, Baumann H, Heintz N, Ganschow RE. Characterization and functional expression of a cDNA encoding egasyn (esterase-22): the endoplasmic reticulum-targeting protein of beta-glucuronidase. Genomics. 11: 956-67. PMID 1783403 DOI: 10.1016/0888-7543(91)90020-F  0.4
1991 McKinney JD, Heintz N. Transcriptional regulation in the eukaryotic cell cycle. Trends in Biochemical Sciences. 16: 430-5. PMID 1776174 DOI: 10.1016/0968-0004(91)90170-Z  1
1991 Shull S, Heintz NH, Periasamy M, Manohar M, Janssen YM, Marsh JP, Mossman BT. Differential regulation of antioxidant enzymes in response to oxidants. The Journal of Biological Chemistry. 266: 24398-403. PMID 1761541  0.4
1991 Segil N, Roberts SB, Heintz N. Mitotic phosphorylation of the Oct-1 homeodomain and regulation of Oct-1 DNA binding activity. Science (New York, N.Y.). 254: 1814-6. PMID 1684878  1
1991 Mulhare P, McQuillen E, Collins C, Heintz N, Howard P. An unusual case using DNA polymorphisms to determine parentage of human remains. The American Journal of Forensic Medicine and Pathology. 12: 157-60. PMID 1679284  0.4
1991 Howard PL, Collins CC, Heintz NH. Polymerase chain reaction and allele-specific oligonucleotides in paternity testing of the deceased. Transfusion. 31: 441-2. PMID 1675501  0.4
1991 Norman DJ, Fletcher C, Heintz N. Genetic mapping of the lurcher locus on mouse chromosome 6 using an intersubspecific backcross. Genomics. 9: 147-53. PMID 1672287 DOI: 10.1016/0888-7543(91)90232-4  1
1991 Heintz N. Transcriptional regulation: Introduction Trends in Biochemical Sciences. 16: 393.  1
1990 Caddle MS, Heintz NH. The replication timing of the amplified dihydrofolate reductase genes in the Chinese hamster ovary cell line CHOC 400. Biochemical and Biophysical Research Communications. 170: 134-9. PMID 2372283 DOI: 10.1016/0006-291X(90)91250-V  0.4
1990 Ross ME, Fletcher C, Mason CA, Hatten ME, Heintz N. Meander tail reveals a discrete developmental unit in the mouse cerebellum. Proceedings of the National Academy of Sciences of the United States of America. 87: 4189-92. PMID 2349228 DOI: 10.1073/pnas.87.11.4189  1
1990 Caddle MS, Lussier RH, Heintz NH. Intramolecular DNA triplexes, bent DNA and DNA unwinding elements in the initiation region of an amplified dihydrofolate reductase replicon. Journal of Molecular Biology. 211: 19-33. PMID 2299670 DOI: 10.1016/0022-2836(90)90008-A  0.4
1990 Bianchi A, Wells RD, Heintz NH, Caddle MS. Sequences near the origin of replication of the DHFR locus of Chinese hamster ovary cells adopt left-handed Z-DNA and triplex structures. The Journal of Biological Chemistry. 265: 21789-96. PMID 2254331  0.4
1990 Caddle MS, Dailey L, Heintz NH. RIP60, a mammalian origin-binding protein, enhances DNA bending near the dihydrofolate reductase origin of replication. Molecular and Cellular Biology. 10: 6236-43. PMID 2247056  0.44
1990 Dailey L, Caddle MS, Heintz N, Heintz NH. Purification of RIP60 and RIP100, mammalian proteins with origin-specific DNA-binding and ATP-dependent DNA helicase activities. Molecular and Cellular Biology. 10: 6225-35. PMID 2174103  0.44
1990 Simon MC, Rooney RJ, Fisch TM, Heintz N, Nevins JR. E1A-dependent trans-activation of the c-fos promoter requires the TATAA sequence. Proceedings of the National Academy of Sciences of the United States of America. 87: 513-7. PMID 2137244 DOI: 10.1073/pnas.87.2.513  1
1990 Heintz NH, Leslie KO, Rogers LA, Howard PL. Amplification of the c-erb B-2 oncogene and prognosis of breast adenocarcinoma. Archives of Pathology & Laboratory Medicine. 114: 160-3. PMID 1967929  0.4
1989 Heintz NH, Howard PL. Hemoglobin Southampton (Casper): characterization of the base mutation. American Journal of Hematology. 30: 1-3. PMID 2910077  0.4
1989 Gallinari P, La Bella F, Heintz N. Characterization and purification of H1TF2, a novel CCAAT-binding protein that interacts with a histone H1 subtype-specific consensus element. Molecular and Cellular Biology. 9: 1566-75. PMID 2725515  1
1989 Heintz N. Temporal regulation of gene expression during the mammalian cell cycle. Current Opinion in Cell Biology. 1: 275-8. PMID 2698680 DOI: 10.1016/0955-0674(89)90100-2  1
1989 La Bella F, Gallinari P, McKinney J, Heintz N. Histone H1 subtype-specific consensus elements mediate cell cycle-regulated transcription in vitro. Genes & Development. 3: 1982-90. PMID 2620829  1
1988 O'Neill EA, Fletcher C, Burrow CR, Heintz N, Roeder RG, Kelly TJ. Transcription factor OTF-1 is functionally identical to the DNA replication factor NF-III. Science (New York, N.Y.). 241: 1210-3. PMID 3413485  1
1988 Heintz NH, Stillman BW. Nuclear DNA synthesis in vitro is mediated via stable replication forks assembled in a temporally specific fashion in vivo. Molecular and Cellular Biology. 8: 1923-31. PMID 3386630  0.4
1988 LaBella F, Sive HL, Roeder RG, Heintz N. Cell-cycle regulation of a human histone H2b gene is mediated by the H2b subtype-specific consensus element. Genes & Development. 2: 32-9. PMID 3128460  1
1988 Dailey L, Roberts SB, Heintz N. Purification of the human histone H4 gene-specific transcription factors H4TF-1 and H4TF-2. Genes & Development. 2: 1700-12. PMID 3071490  1
1988 Howard PL, Hoag JB, Bovill EG, Heintz NH. Spontaneous mutation in the male gamete as a cause of hemophilia A: clarification of a case using DNA probes. American Journal of Hematology. 28: 167-9. PMID 2900604  0.4
1988 Simon MC, Fisch TM, Benecke BJ, Nevins JR, Heintz N. Definition of multiple, functionally distinct TATA elements, one of which is a target in the hsp70 promoter for E1A regulation. Cell. 52: 723-9. PMID 2830991 DOI: 10.1016/0092-8674(88)90410-2  1
1988 Huber SA, Heintz N, Tracy R. Coxsackievirus B-3-induced myocarditis. Virus and actinomycin D treatment of myocytes induces novel antigens recognized by cytolytic T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 141: 3214-9. PMID 2459248  0.4
1988 La Bella F, Zhong R, Heintz N. Cell type-specific expression of a human histone H1 gene. The Journal of Biological Chemistry. 263: 2115-8. PMID 2448304  1
1987 Fletcher C, Heintz N, Roeder RG. Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene. Cell. 51: 773-81. PMID 3677172 DOI: 10.1016/0092-8674(87)90100-0  1
1987 Capasso O, Bleecker GC, Heintz N. Sequences controlling histone H4 mRNA abundance. The Embo Journal. 6: 1825-31. PMID 3608993  1
1987 Kaczmarek L, Calabretta B, Kao HT, Heintz N, Nevins J, Baserga R. Control of hsp70 RNA levels in human lymphocytes. The Journal of Cell Biology. 104: 183-7. PMID 3492498  1
1987 Dailey L, Roberts SB, Heintz N. RNA polymerase II transcription factors H4TF-1 and H4TF-2 require metal to bind specific DNA sequences. Molecular and Cellular Biology. 7: 4582-4. PMID 3437898  1
1987 Simon MC, Kitchener K, Kao HT, Hickey E, Weber L, Voellmy R, Heintz N, Nevins JR. Selective induction of human heat shock gene transcription by the adenovirus E1A gene products, including the 12S E1A product. Molecular and Cellular Biology. 7: 2884-90. PMID 2959854 DOI: 10.1128/MCB.7.8.2884  1
1986 Dailey L, Hanly SM, Roeder RG, Heintz N. Distinct transcription factors bind specifically to two regions of the human histone H4 promoter. Proceedings of the National Academy of Sciences of the United States of America. 83: 7241-5. PMID 3463962  1
1986 Burhans WC, Selegue JE, Heintz NH. Isolation of the origin of replication associated with the amplified Chinese hamster dihydrofolate reductase domain. Proceedings of the National Academy of Sciences of the United States of America. 83: 7790-4. PMID 3094015 DOI: 10.1073/PNAS.83.20.7790  0.4
1986 Sive HL, Heintz N, Roeder RG. Multiple sequence elements are required for maximal in vitro transcription of a human histone H2B gene. Molecular and Cellular Biology. 6: 3329-40. PMID 3025588  1
1986 Burhans WC, Selegue JE, Heintz NH. Replication intermediates formed during initiation of DNA synthesis in methotrexate-resistant CHOC 400 cells are enriched for sequences derived from a specific, amplified restriction fragment Biochemistry. 25: 441-449.  0.4
1985 Hanly SM, Bleecker GC, Heintz N. Identification of promoter elements necessary for transcriptional regulation of a human histone H4 gene in vitro. Molecular and Cellular Biology. 5: 380-9. PMID 3974574  1
1985 Kao HT, Capasso O, Heintz N, Nevins JR. Cell cycle control of the human HSP70 gene: implications for the role of a cellular E1A-like function. Molecular and Cellular Biology. 5: 628-33. PMID 3872994 DOI: 10.1128/MCB.5.4.628  1
1985 Capasso O, Heintz N. Regulated expression of mammalian histone H4 genes in vivo requires a trans-acting transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 82: 5622-6. PMID 3862085  1
1984 Heintz N, Roeder RG. Transcription of human histone genes in extracts from synchronized HeLa cells. Proceedings of the National Academy of Sciences of the United States of America. 81: 2713-7. PMID 6585823  1
1984 Sive HL, Heintz N, Roeder RG. Regulation of human histone gene expression during the HeLa cell cycle requires protein synthesis. Molecular and Cellular Biology. 4: 2723-34. PMID 6441888  1
1983 Zhong R, Roeder RG, Heintz N. The primary structure and expression of four cloned human histone genes. Nucleic Acids Research. 11: 7409-25. PMID 6647026 DOI: 10.1093/nar/11.21.7409  1
1983 Strayer D, Heintz N, Roeder R, Gillespie D. Three organizations of human DNA. Proceedings of the National Academy of Sciences of the United States of America. 80: 4770-4. PMID 6576359  1
1983 Heintz N, Sive HL, Roeder RG. Regulation of human histone gene expression: kinetics of accumulation and changes in the rate of synthesis and in the half-lives of individual histone mRNAs during the HeLa cell cycle. Molecular and Cellular Biology. 3: 539-50. PMID 6406835  1
1981 Heintz NH, Tierney B, Bresnick E, Schaeffer WI. Correlation of induction of aryl hydrocarbon hydroxylase in cultured rat hepatocytes with saturable high-affinity binding of 3-methylcholanthrene to a 4S cytoplasmic protein. Cancer Research. 41: 1794-802. PMID 7214346  0.4
1981 Heintz N, Zernik M, Roeder RG. The structure of the human histone genes: clustered but not tandemly repeated. Cell. 24: 661-8. PMID 6265100 DOI: 10.1016/0092-8674(81)90092-1  1
1981 Tierney B, Holder GM, Heintz NH. Polycyclic aromatic hydrocarbon binding to cytosolic proteins: Nuclear uptake and subsequent metabolism in rat liver preparations Proceedings of the American Association For Cancer Research. 380.  0.4
1980 Zernik M, Heintz N, Boime I, Roeder RG. Xenopus laevis histone genes: variant H1 genes are present in different clusters. Cell. 22: 807-15. PMID 7460012 DOI: 10.1016/0092-8674(80)90557-7  1
1980 Heintz N, Little B, Bresnick E, Schaeffer WI. Malignant transformation of cultured rat hepatocytes by (+)- and (-)-trans-7,8-dihydro-7,8-dihydroxybenzo(a)pyrene. Cancer Research. 40: 1281-5. PMID 7188884  0.4
1980 Heintz NH, Tierney B, Bresnick EB, Schaeffer WI. Saturable, high affinity binding of 3-methyl-cholanthrene to a 4S cytoplasmic protein correlates to AHH induction in cultured rat hepatocytes In Vitro. 16.  0.4
1979 Schaeffer WI, Chuang AH, Heintz N, Bresnick E. Sensitivity of cultured rat hepatocytes to aflatoxin B1 and benzo(a)pyrene. In Vitro. 15: 437-40. PMID 478568 DOI: 10.1007/BF02618412  0.4
1979 Schaeffer WI, Heintz N, Bresnick E. Malignant transformation of cultured rat hepatocytes by (+) and (-) trans 7,8-dihydroxy,7,8-dihydrobenzo(a)pyrene Proceedings of the American Association For Cancer Research 0.4
1978 Schaeffer WI, Heintz NH. A diploid rat liver cell culture. IV. Malignant transformation by aflatoxin B1. In Vitro. 14: 418-27. PMID 669735 DOI: 10.1007/BF02616103  0.4
1978 Mossman BT, Heintz N, Macpherson BV, Craighead JE. Squamous metaplasia of the tracheal epithelium in organ culture. II. Nutritional influences. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 157: 500-5. PMID 634992 DOI: 10.3181/00379727-157-40085  0.4
1977 Schaeffer WI, Heintz NH, Chuang AHL, Bresnick E. Sensitivity of early vs late passages of a rat hepatocyte culture for toxicological studies of carcinogens In Vitro. 13.  0.4
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