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Andrew P. McMahon - Publications

Affiliations: 
2012 Molecular and Cellular Biology Harvard University, Cambridge, MA, United States 
 2012- Biological Sciences University of Southern California, Los Angeles, CA, United States 
Area:
sonic hedgehog, patterning, nervous system
Website:
https://keck.usc.edu/faculty-search/andrew-p-mcmahon/
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334 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Polonsky M, Gerhardt LMS, Yun J, Koppitch K, Colón KL, Amrhein H, Wold B, Zheng S, Yuan GC, Thomson M, Cai L, McMahon AP. Spatial transcriptomics defines injury specific microenvironments and cellular interactions in kidney regeneration and disease. Nature Communications. 15: 7010. PMID 39237549 DOI: 10.1038/s41467-024-51186-z  0.565
2024 Kim S, Koppitch K, Parvez RK, Guo J, Achieng M, Schnell J, Lindström NO, McMahon AP. Comparative single-cell analyses identify shared and divergent features of human and mouse kidney development. Developmental Cell. PMID 39121855 DOI: 10.1016/j.devcel.2024.07.013  0.307
2023 Der B, Bugacov H, Briantseva BM, McMahon AP. Cadherin Adhesion Complexes Direct Cell Aggregation in the Epithelial Transition of Wnt-Induced Nephron Progenitor Cells. Biorxiv : the Preprint Server For Biology. PMID 38654822 DOI: 10.1101/2023.08.27.555021  0.306
2023 Khalil NN, Petersen AP, Song CJ, Chen Y, Takamoto K, Kellogg AC, Chen EZ, McMahon AP, McCain ML. User-friendly microfluidic system reveals native-like morphological and transcriptomic phenotypes induced by shear stress in proximal tubule epithelium. Apl Bioengineering. 7: 036106. PMID 37584027 DOI: 10.1063/5.0143614  0.416
2023 Kim S, Koppitch K, Parvez RK, Guo J, Achieng M, Schnell J, Lindström NO, McMahon AP. Comparative single-cell analyses identify shared and divergent features of human and mouse kidney development. Biorxiv : the Preprint Server For Biology. PMID 37293066 DOI: 10.1101/2023.05.16.540880  0.3
2022 Tran T, Song CJ, Nguyen T, Cheng SY, McMahon JA, Yang R, Guo Q, Der B, Lindström NO, Lin DC, McMahon AP. A scalable organoid model of human autosomal dominant polycystic kidney disease for disease mechanism and drug discovery. Cell Stem Cell. 29: 1083-1101.e7. PMID 35803227 DOI: 10.1016/j.stem.2022.06.005  0.779
2022 Xu J, Liu Y, Li H, Tarashansky AJ, Kalicki CH, Hung RJ, Hu Y, Comjean A, Kolluru SS, Wang B, Quake SR, Luo L, McMahon AP, Dow JAT, Perrimon N. Transcriptional and functional motifs defining renal function revealed by single-nucleus RNA sequencing. Proceedings of the National Academy of Sciences of the United States of America. 119: e2203179119. PMID 35696569 DOI: 10.1073/pnas.2203179119  0.302
2020 Cornelius RJ, Sharma A, Su XT, Guo JJ, McMahon JA, Ellison DH, McMahon AP, McCormick JA. A novel distal convoluted tubule-specific Cre-recombinase driven by the NaCl cotransporter gene. American Journal of Physiology. Renal Physiology. PMID 32657158 DOI: 10.1152/Ajprenal.00101.2020  0.361
2020 Rutledge EA, McMahon AP. Mutational analysis of genes with ureteric progenitor cell-specific expression in branching morphogenesis of the mouse kidney. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 32017326 DOI: 10.1002/Dvdy.157  0.424
2019 Rutledge EA, Lindström NO, Michos O, McMahon AP. Genetic manipulation of ureteric bud tip progenitors in the mammalian kidney through an Adamts18 enhancer driven tet-on inducible system. Developmental Biology. PMID 31734175 DOI: 10.1016/J.Ydbio.2019.11.007  0.458
2019 Ransick A, Lindström NO, Liu J, Zhu Q, Guo JJ, Alvarado GF, Kim AD, Black HG, Kim J, McMahon AP. Single-Cell Profiling Reveals Sex, Lineage, and Regional Diversity in the Mouse Kidney. Developmental Cell. 51: 399-413.e7. PMID 31689386 DOI: 10.1016/J.Devcel.2019.10.005  0.378
2019 Kim AD, Lake BB, Chen S, Wu Y, Guo J, Parvez RK, Tran T, Thornton ME, Grubbs B, McMahon JA, Zhang K, McMahon AP. Cellular Recruitment by Podocyte-Derived Pro-migratory Factors in Assembly of the Human Renal Filter. Iscience. 20: 402-414. PMID 31622881 DOI: 10.1016/J.Isci.2019.09.029  0.388
2019 Tran T, Lindström NO, Ransick A, De Sena Brandine G, Guo Q, Kim AD, Der B, Peti-Peterdi J, Smith AD, Thornton M, Grubbs B, McMahon JA, McMahon AP. In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes. Developmental Cell. 50: 102-116.e6. PMID 31265809 DOI: 10.1016/J.Devcel.2019.06.001  0.432
2019 Rutledge EA, Parvez RK, Short KM, Smyth IM, McMahon AP. Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease. Developmental Biology. PMID 31242448 DOI: 10.1016/J.Ydbio.2019.06.012  0.411
2019 Menshykau D, Michos O, Lang C, Conrad L, McMahon AP, Iber D. Image-based modeling of kidney branching morphogenesis reveals GDNF-RET based Turing-type mechanism and pattern-modulating WNT11 feedback. Nature Communications. 10: 239. PMID 30651543 DOI: 10.1038/S41467-018-08212-8  0.34
2018 O'Brien LL, Combes AN, Short KM, Lindström NO, Whitney PH, Cullen-McEwen LA, Ju A, Abdelhalim A, Michos O, Bertram JF, Smyth IM, Little MH, McMahon AP. Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment. Elife. 7. PMID 30516471 DOI: 10.7554/Elife.40392  0.465
2018 Hasenpusch-Theil K, West S, Kelman A, Kozic Z, Horrocks S, McMahon AP, Price DJ, Mason JO, Theil T. controls the onset of cortical neurogenesis by regulating the radial glial cell cycle through expression. Development (Cambridge, England). PMID 30093555 DOI: 10.1242/Dev.163147  0.36
2018 Przepiorski A, Sander V, Tran T, Hollywood JA, Sorrenson B, Shih JH, Wolvetang EJ, McMahon AP, Holm TM, Davidson AJ. A Simple Bioreactor-Based Method to Generate Kidney Organoids from Pluripotent Stem Cells. Stem Cell Reports. PMID 30033089 DOI: 10.1016/J.Stemcr.2018.06.018  0.37
2018 Lindström NO, De Sena Brandine G, Tran T, Ransick A, Suh G, Guo J, Kim AD, Parvez RK, Ruffins SW, Rutledge EA, Thornton ME, Grubbs B, McMahon JA, Smith AD, McMahon AP. Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis. Developmental Cell. 45: 651-660.e4. PMID 29870722 DOI: 10.1016/J.Devcel.2018.05.010  0.421
2018 Ramalingam H, Fessler AR, Das A, Valerius MT, Basta J, Robbins L, Brown AC, Oxburgh L, McMahon AP, Rauchman M, Carroll TJ. Disparate levels of beta-catenin activity determine nephron progenitor cell fate. Developmental Biology. PMID 29705331 DOI: 10.1016/J.Ydbio.2018.04.020  0.448
2018 Tan Z, Niu B, Tsang KY, Melhado IG, Ohba S, He X, Huang Y, Wang C, McMahon AP, Jauch R, Chan D, Zhang MQ, Cheah KSE. Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions. Plos Genetics. 14: e1007346. PMID 29659575 DOI: 10.1371/Journal.Pgen.1007346  0.423
2018 Lindström NO, McMahon JA, Guo J, Tran T, Guo Q, Rutledge E, Parvez RK, Saribekyan G, Schuler RE, Liao C, Kim AD, Abdelhalim A, Ruffins SW, Thornton ME, Basking L, ... ... McMahon AP, et al. Conserved and Divergent Features of Human and Mouse Kidney Organogenesis. Journal of the American Society of Nephrology : Jasn. PMID 29449453 DOI: 10.1681/Asn.2017080887  0.371
2018 Lindström NO, Tran T, Guo J, Rutledge E, Parvez RK, Thornton ME, Grubbs B, McMahon JA, McMahon AP. Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning. Journal of the American Society of Nephrology : Jasn. PMID 29449451 DOI: 10.1681/Asn.2017091036  0.386
2018 Lindström NO, Guo J, Kim AD, Tran T, Guo Q, De Sena Brandine G, Ransick A, Parvez RK, Thornton ME, Basking L, Grubbs B, McMahon JA, Smith AD, McMahon AP. Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney. Journal of the American Society of Nephrology : Jasn. PMID 29449449 DOI: 10.1681/Asn.2017080890  0.43
2018 O'Brien LL, Guo Q, Bahrami-Samani E, Park JS, Hasso SM, Lee YJ, Fang A, Kim AD, Guo J, Hong TM, Peterson KA, Lozanoff S, Raviram R, Ren B, Fogelgren B, ... ... McMahon AP, et al. Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies. Plos Genetics. 14: e1007181. PMID 29377931 DOI: 10.1371/Journal.Pgen.1007181  0.591
2017 Wegner KA, Cadena MT, Trevena R, Turco AE, Gottschalk A, Halberg RB, Guo J, McMahon JA, McMahon AP, Vezina CM. An immunohistochemical identification key for cell types in adult mouse prostatic and urethral tissue sections. Plos One. 12: e0188413. PMID 29145476 DOI: 10.1371/Journal.Pone.0188413  0.315
2017 Liu J, Kumar S, Dolzhenko E, Alvarado GF, Guo J, Lu C, Chen Y, Li M, Dessing MC, Parvez RK, Cippà PE, Krautzberger AM, Saribekyan G, Smith AD, McMahon AP. Molecular characterization of the transition from acute to chronic kidney injury following ischemia/reperfusion. Jci Insight. 2. PMID 28931758 DOI: 10.1172/Jci.Insight.94716  0.304
2017 Rutledge EA, Benazet JD, McMahon AP. Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development (Cambridge, England). PMID 28705898 DOI: 10.1242/Dev.149112  0.415
2017 Naiman N, Fujioka K, Fujino M, Valerius MT, Potter SS, McMahon AP, Kobayashi A. Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Developmental Cell. 41: 349-365.e3. PMID 28535371 DOI: 10.1016/J.Devcel.2017.04.022  0.379
2017 Minegishi K, Hashimoto M, Ajima R, Takaoka K, Shinohara K, Ikawa Y, Nishimura H, McMahon AP, Willert K, Okada Y, Sasaki H, Shi D, Fujimori T, Ohtsuka T, Igarashi Y, et al. A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking. Developmental Cell. 40: 439-452.e4. PMID 28292423 DOI: 10.1016/J.Devcel.2017.02.010  0.371
2017 Wu F, Zhang Y, Sun B, McMahon AP, Wang Y. Hedgehog Signaling: From Basic Biology to Cancer Therapy. Cell Chemical Biology. PMID 28286127 DOI: 10.1016/J.Chembiol.2017.02.010  0.353
2017 Oxburgh L, Carroll TJ, Cleaver O, Gossett DR, Hoshizaki DK, Hubbell JA, Humphreys BD, Jain S, Jensen J, Kaplan DL, Kesselman C, Ketchum CJ, Little MH, McMahon AP, Shankland SJ, et al. (Re)Building a Kidney. Journal of the American Society of Nephrology : Jasn. PMID 28096308 DOI: 10.1681/Asn.2016101077  0.396
2017 Combes A, Lefevre J, Short K, Ju A, Georgas K, Lamberton T, Cairncross O, Rumballe B, McMahon A, Little M, Hamilton N, Smyth I. An integrated cell, tissue and whole organ profile of kidney morphogenesis Mechanisms of Development. 145. DOI: 10.1016/J.Mod.2017.04.432  0.31
2016 Hojo H, McMahon AP, Ohba S. An Emerging Regulatory Landscape for Skeletal Development. Trends in Genetics : Tig. PMID 27814929 DOI: 10.1016/J.Tig.2016.10.001  0.397
2016 He X, Ohba S, Hojo H, McMahon AP. AP-1 family members act with Sox9 to promote chondrocyte hypertrophy. Development (Cambridge, England). PMID 27471255 DOI: 10.1242/Dev.134502  0.346
2016 Lorberbaum DS, Ramos AI, Peterson KA, Carpenter BS, Parker DS, De S, Hillers LE, Blake VM, Nishi Y, McFarlane MR, Chiang AC, Kassis JA, Allen BL, McMahon AP, Barolo S. An ancient yet flexible cis-regulatory architecture allows localized Hedgehog tuning by patched/Ptch1. Elife. 5. PMID 27146892 DOI: 10.7554/Elife.13550  0.807
2016 McMahon AP. Development of the Mammalian Kidney. Current Topics in Developmental Biology. 117: 31-64. PMID 26969971 DOI: 10.1016/Bs.Ctdb.2015.10.010  0.381
2016 O'Brien LL, Guo Q, Lee Y, Tran T, Benazet JD, Whitney PH, Valouev A, McMahon AP. Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators. Development (Cambridge, England). 143: 595-608. PMID 26884396 DOI: 10.1242/Dev.127175  0.409
2016 Lorberbaum DS, Ramos AI, Peterson KA, Carpenter BS, Parker DS, De S, Hillers LE, Blake VM, Nishi Y, McFarlane MR, Chiang AC, Kassis JA, Allen BL, McMahon AP, Barolo S. Author response: An ancient yet flexible cis-regulatory architecture allows localized Hedgehog tuning by patched/Ptch1 Elife. DOI: 10.7554/Elife.13550.030  0.752
2015 Hettmer S, Lin MM, Tchessalova D, Tortorici SJ, Castiglioni A, Desai T, Mao J, McMahon AP, Wagers AJ. Hedgehog-driven myogenic tumors recapitulate skeletal muscle cellular heterogeneity. Experimental Cell Research. PMID 26460176 DOI: 10.1016/J.Yexcr.2015.10.008  0.327
2015 Nishi Y, Zhang X, Jeong J, Peterson KA, Vedenko A, Bulyk ML, Hide WA, McMahon AP. A direct fate exclusion mechanism by Sonic hedgehog-regulated transcriptional repressors. Development (Cambridge, England). 142: 3286-93. PMID 26293298 DOI: 10.1242/Dev.124636  0.675
2015 Kumar S, Liu J, Pang P, Krautzberger AM, Reginensi A, Akiyama H, Schedl A, Humphreys BD, McMahon AP. Sox9 Activation Highlights a Cellular Pathway of Renal Repair in the Acutely Injured Mammalian Kidney. Cell Reports. 12: 1325-38. PMID 26279573 DOI: 10.1016/J.Celrep.2015.07.034  0.371
2015 Ohba S, He X, Hojo H, McMahon AP. Distinct Transcriptional Programs Underlie Sox9 Regulation of the Mammalian Chondrocyte. Cell Reports. 12: 229-43. PMID 26146088 DOI: 10.1016/J.Celrep.2015.06.013  0.36
2015 Li J, Ariunbold U, Suhaimi N, Sunn N, Guo J, McMahon JA, McMahon AP, Little M. Collecting duct-derived cells display mesenchymal stem cell properties and retain selective in vitro and in vivo epithelial capacity. Journal of the American Society of Nephrology : Jasn. 26: 81-94. PMID 24904087 DOI: 10.1681/Asn.2013050517  0.435
2014 Junker JP, Peterson KA, Nishi Y, Mao J, McMahon AP, van Oudenaarden A. A predictive model of bifunctional transcription factor signaling during embryonic tissue patterning. Developmental Cell. 31: 448-60. PMID 25458012 DOI: 10.1016/J.Devcel.2014.10.017  0.425
2014 Junker JP, Noël ES, Guryev V, Peterson KA, Shah G, Huisken J, McMahon AP, Berezikov E, Bakkers J, van Oudenaarden A. Genome-wide RNA Tomography in the zebrafish embryo. Cell. 159: 662-75. PMID 25417113 DOI: 10.1016/J.Cell.2014.09.038  0.327
2014 Kobayashi A, Mugford JW, Krautzberger AM, Naiman N, Liao J, McMahon AP. Identification of a multipotent self-renewing stromal progenitor population during mammalian kidney organogenesis. Stem Cell Reports. 3: 650-62. PMID 25358792 DOI: 10.1016/J.Stemcr.2014.08.008  0.785
2014 Hoffmann AD, Yang XH, Burnicka-Turek O, Bosman JD, Ren X, Steimle JD, Vokes SA, McMahon AP, Kalinichenko VV, Moskowitz IP. Foxf genes integrate tbx5 and hedgehog pathways in the second heart field for cardiac septation. Plos Genetics. 10: e1004604. PMID 25356765 DOI: 10.1371/Journal.Pgen.1004604  0.378
2014 Lai LP, Lotinun S, Bouxsein ML, Baron R, McMahon AP. Stk11 (Lkb1) deletion in the osteoblast lineage leads to high bone turnover, increased trabecular bone density and cortical porosity. Bone. 69: 98-108. PMID 25240456 DOI: 10.1016/J.Bone.2014.09.010  0.304
2014 Kumar S, Liu J, McMahon AP. Defining the acute kidney injury and repair transcriptome. Seminars in Nephrology. 34: 404-17. PMID 25217269 DOI: 10.1016/J.Semnephrol.2014.06.007  0.343
2014 O'Brien LL, McMahon AP. Induction and patterning of the metanephric nephron. Seminars in Cell & Developmental Biology. 36: 31-8. PMID 25194660 DOI: 10.1016/J.Semcdb.2014.08.014  0.387
2014 Lopez-Rios J, Duchesne A, Speziale D, Andrey G, Peterson KA, Germann P, Unal E, Liu J, Floriot S, Barbey S, Gallard Y, Müller-Gerbl M, Courtney AD, Klopp C, Rodriguez S, ... ... McMahon AP, et al. Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs. Nature. 511: 46-51. PMID 24990743 DOI: 10.1038/Nature13289  0.428
2014 Short KM, Combes AN, Lefevre J, Ju AL, Georgas KM, Lamberton T, Cairncross O, Rumballe BA, McMahon AP, Hamilton NA, Smyth IM, Little MH. Global quantification of tissue dynamics in the developing mouse kidney. Developmental Cell. 29: 188-202. PMID 24780737 DOI: 10.1016/J.Devcel.2014.02.017  0.372
2014 Grgic I, Krautzberger AM, Hofmeister A, Lalli M, DiRocco DP, Fleig SV, Liu J, Duffield JS, McMahon AP, Aronow B, Humphreys BD. Translational profiles of medullary myofibroblasts during kidney fibrosis. Journal of the American Society of Nephrology : Jasn. 25: 1979-90. PMID 24652793 DOI: 10.1681/Asn.2013101143  0.375
2014 Liu J, Krautzberger AM, Sui SH, Hofmann OM, Chen Y, Baetscher M, Grgic I, Kumar S, Humphreys BD, Humphreys B, Hide WA, McMahon AP. Cell-specific translational profiling in acute kidney injury. The Journal of Clinical Investigation. 124: 1242-54. PMID 24569379 DOI: 10.1172/Jci72126  0.369
2013 Wang Y, McMahon AP. A novel site comes into sight. Elife. 2: e01680. PMID 24302574 DOI: 10.7554/Elife.01680  0.302
2013 Lai LP, Lilley BN, Sanes JR, McMahon AP. Lkb1/Stk11 regulation of mTOR signaling controls the transition of chondrocyte fates and suppresses skeletal tumor formation. Proceedings of the National Academy of Sciences of the United States of America. 110: 19450-5. PMID 24218567 DOI: 10.1073/Pnas.1309001110  0.4
2013 Gandhi D, Molotkov A, Batourina E, Schneider K, Dan H, Reiley M, Laufer E, Metzger D, Liang F, Liao Y, Sun TT, Aronow B, Rosen R, Mauney J, Adam R, ... ... McMahon A, et al. Retinoid signaling in progenitors controls specification and regeneration of the urothelium. Developmental Cell. 26: 469-82. PMID 23993789 DOI: 10.1016/J.Devcel.2013.07.017  0.399
2013 Humphreys BD, Xu F, Sabbisetti V, Grgic I, Naini SM, Wang N, Chen G, Xiao S, Patel D, Henderson JM, Ichimura T, Mou S, Soeung S, McMahon AP, Kuchroo VK, et al. Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis. The Journal of Clinical Investigation. 123: 4023-35. PMID 23979159 DOI: 10.1172/Jci45361  0.335
2013 Holtz AM, Peterson KA, Nishi Y, Morin S, Song JY, Charron F, McMahon AP, Allen BL. Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning. Development (Cambridge, England). 140: 3423-34. PMID 23900540 DOI: 10.1242/Dev.095083  0.825
2013 Hettmer S, Teot LA, van Hummelen P, MacConaill L, Bronson RT, Dall'Osso C, Mao J, McMahon AP, Gruber PJ, Grier HE, Rodriguez-Galindo C, Fletcher CD, Wagers AJ. Mutations in Hedgehog pathway genes in fetal rhabdomyomas. The Journal of Pathology. 231: 44-52. PMID 23780909 DOI: 10.1002/Path.4229  0.394
2013 DiRocco DP, Kobayashi A, Taketo MM, McMahon AP, Humphreys BD. Wnt4/β-catenin signaling in medullary kidney myofibroblasts. Journal of the American Society of Nephrology : Jasn. 24: 1399-412. PMID 23766539 DOI: 10.1681/Asn.2012050512  0.491
2013 McMahon AP, Hasso SM. Filopodia: the cellular quills of hedgehog signaling? Developmental Cell. 25: 328-30. PMID 23725760 DOI: 10.1016/J.Devcel.2013.05.008  0.368
2013 Zhang X, Peterson KA, Liu XS, McMahon AP, Ohba S. Gene regulatory networks mediating canonical Wnt signal-directed control of pluripotency and differentiation in embryo stem cells. Stem Cells (Dayton, Ohio). 31: 2667-79. PMID 23505158 DOI: 10.1002/Stem.1371  0.584
2013 Kamberov YG, Wang S, Tan J, Gerbault P, Wark A, Tan L, Yang Y, Li S, Tang K, Chen H, Powell A, Itan Y, Fuller D, Lohmueller J, Mao J, ... ... McMahon AP, et al. Modeling recent human evolution in mice by expression of a selected EDAR variant. Cell. 152: 691-702. PMID 23415220 DOI: 10.1016/J.Cell.2013.01.016  0.303
2013 Mae S, Shono A, Shiota F, Yasuno T, Kajiwara M, Gotoda-Nishimura N, Arai S, Sato-Otubo A, Toyoda T, Takahashi K, Nakayama N, Cowan CA, Aoi T, Ogawa S, McMahon AP, et al. Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells. Nature Communications. 4: 1367. PMID 23340407 DOI: 10.1038/Ncomms2378  0.388
2013 O'Brien LL, McMahon AP. Progenitor programming in mammalian nephrogenesis. Nephrology (Carlton, Vic.). 18: 177-9. PMID 23279704 DOI: 10.1111/Nep.12027  0.324
2012 Peterson KA, Nishi Y, Ma W, Vedenko A, Shokri L, Zhang X, McFarlane M, Baizabal JM, Junker JP, van Oudenaarden A, Mikkelsen T, Bernstein BE, Bailey TL, Bulyk ML, Wong WH, ... McMahon AP, et al. Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning. Genes & Development. 26: 2802-16. PMID 23249739 DOI: 10.1101/Gad.207142.112  0.549
2012 Maatouk DM, Mork L, Hinson A, Kobayashi A, McMahon AP, Capel B. Germ cells are not required to establish the female pathway in mouse fetal gonads. Plos One. 7: e47238. PMID 23091613 DOI: 10.1371/Journal.Pone.0047238  0.402
2012 Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM. A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. Frontiers in Neuroscience. 6: 130. PMID 22988430 DOI: 10.3389/Fnins.2012.00130  0.426
2012 Wang Y, Davidow L, Arvanites AC, Blanchard J, Lam K, Xu K, Oza V, Yoo JW, Ng JM, Curran T, Rubin LL, McMahon AP. Glucocorticoid compounds modify smoothened localization and hedgehog pathway activity. Chemistry & Biology. 19: 972-82. PMID 22921064 DOI: 10.1016/J.Chembiol.2012.06.012  0.391
2012 Kao RM, Vasilyev A, Miyawaki A, Drummond IA, McMahon AP. Invasion of distal nephron precursors associates with tubular interconnection during nephrogenesis. Journal of the American Society of Nephrology : Jasn. 23: 1682-90. PMID 22904347 DOI: 10.1681/Asn.2012030283  0.807
2012 Park JS, Ma W, O'Brien LL, Chung E, Guo JJ, Cheng JG, Valerius MT, McMahon JA, Wong WH, McMahon AP. Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks. Developmental Cell. 23: 637-51. PMID 22902740 DOI: 10.1016/J.Devcel.2012.07.008  0.595
2012 Guha A, Vasconcelos M, Cai Y, Yoneda M, Hinds A, Qian J, Li G, Dickel L, Johnson JE, Kimura S, Guo J, McMahon J, McMahon AP, Cardoso WV. Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways. Proceedings of the National Academy of Sciences of the United States of America. 109: 12592-7. PMID 22797898 DOI: 10.1073/Pnas.1204710109  0.508
2012 Wang Y, Arvanites AC, Davidow L, Blanchard J, Lam K, Yoo JW, Coy S, Rubin LL, McMahon AP. Selective identification of hedgehog pathway antagonists by direct analysis of smoothened ciliary translocation. Acs Chemical Biology. 7: 1040-8. PMID 22554036 DOI: 10.1021/Cb300028A  0.356
2012 Little MH, McMahon AP. Mammalian kidney development: principles, progress, and projections. Cold Spring Harbor Perspectives in Biology. 4. PMID 22550230 DOI: 10.1101/Cshperspect.A008300  0.431
2012 Yu J, Valerius MT, Duah M, Staser K, Hansard JK, Guo JJ, McMahon J, Vaughan J, Faria D, Georgas K, Rumballe B, Ren Q, Krautzberger AM, Junker JP, Thiagarajan RD, ... ... McMahon AP, et al. Identification of molecular compartments and genetic circuitry in the developing mammalian kidney. Development (Cambridge, England). 139: 1863-73. PMID 22510988 DOI: 10.1242/Dev.074005  0.639
2012 Rajurkar M, De Jesus-Monge WE, Driscoll DR, Appleman VA, Huang H, Cotton JL, Klimstra DS, Zhu LJ, Simin K, Xu L, McMahon AP, Lewis BC, Mao J. The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 109: E1038-47. PMID 22493246 DOI: 10.1073/Pnas.1114168109  0.323
2012 Fabian SL, Penchev RR, St-Jacques B, Rao AN, Sipilä P, West KA, McMahon AP, Humphreys BD. Hedgehog-Gli pathway activation during kidney fibrosis. The American Journal of Pathology. 180: 1441-53. PMID 22342522 DOI: 10.1016/J.Ajpath.2011.12.039  0.497
2012 Chong HJ, Young NM, Hu D, Jeong J, McMahon AP, Hallgrimsson B, Marcucio RS. Signaling by SHH rescues facial defects following blockade in the brain. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 241: 247-56. PMID 22275045 DOI: 10.1002/Dvdy.23726  0.61
2012 Tsanov KM, Nishi Y, Peterson KA, Liu J, Baetscher M, McMahon AP. An embryonic stem cell-based system for rapid analysis of transcriptional enhancers. Genesis (New York, N.Y. : 2000). 50: 443-50. PMID 22083581 DOI: 10.1002/Dvg.20820  0.429
2012 Mork L, Maatouk DM, McMahon JA, Guo JJ, Zhang P, McMahon AP, Capel B. Temporal differences in granulosa cell specification in the ovary reflect distinct follicle fates in mice. Biology of Reproduction. 86: 37. PMID 21976597 DOI: 10.1095/Biolreprod.111.095208  0.389
2011 Boyle SC, Kim M, Valerius MT, McMahon AP, Kopan R. Notch pathway activation can replace the requirement for Wnt4 and Wnt9b in mesenchymal-to-epithelial transition of nephron stem cells. Development (Cambridge, England). 138: 4245-54. PMID 21852398 DOI: 10.1242/Dev.070433  0.478
2011 Izzi L, Lévesque M, Morin S, Laniel D, Wilkes BC, Mille F, Krauss RS, McMahon AP, Allen BL, Charron F. Boc and Gas1 each form distinct Shh receptor complexes with Ptch1 and are required for Shh-mediated cell proliferation. Developmental Cell. 20: 788-801. PMID 21664577 DOI: 10.1016/J.Devcel.2011.04.017  0.647
2011 Allen BL, Song JY, Izzi L, Althaus IW, Kang JS, Charron F, Krauss RS, McMahon AP. Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function. Developmental Cell. 20: 775-87. PMID 21664576 DOI: 10.1016/J.Devcel.2011.04.018  0.67
2011 Harding SD, Armit C, Armstrong J, Brennan J, Cheng Y, Haggarty B, Houghton D, Lloyd-MacGilp S, Pi X, Roochun Y, Sharghi M, Tindal C, McMahon AP, Gottesman B, Little MH, et al. The GUDMAP database--an online resource for genitourinary research. Development (Cambridge, England). 138: 2845-53. PMID 21652655 DOI: 10.1242/Dev.063594  0.323
2011 Nagalakshmi VK, Ren Q, Pugh MM, Valerius MT, McMahon AP, Yu J. Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney. Kidney International. 79: 317-30. PMID 20944551 DOI: 10.1038/Ki.2010.385  0.342
2010 Amadi OC, Steinhauser ML, Nishi Y, Chung S, Kamm RD, McMahon AP, Lee RT. A low resistance microfluidic system for the creation of stable concentration gradients in a defined 3D microenvironment. Biomedical Microdevices. 12: 1027-41. PMID 20661647 DOI: 10.1007/S10544-010-9457-7  0.303
2010 Lee EY, Ji H, Ouyang Z, Zhou B, Ma W, Vokes SA, McMahon AP, Wong WH, Scott MP. Hedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 9736-41. PMID 20460306 DOI: 10.1073/Pnas.1004602107  0.39
2010 Mao J, Kim BM, Rajurkar M, Shivdasani RA, McMahon AP. Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract. Development (Cambridge, England). 137: 1721-9. PMID 20430747 DOI: 10.1242/Dev.044586  0.499
2010 Lin SL, Li B, Rao S, Yeo EJ, Hudson TE, Nowlin BT, Pei H, Chen L, Zheng JJ, Carroll TJ, Pollard JW, McMahon AP, Lang RA, Duffield JS. Macrophage Wnt7b is critical for kidney repair and regeneration. Proceedings of the National Academy of Sciences of the United States of America. 107: 4194-9. PMID 20160075 DOI: 10.1073/Pnas.0912228107  0.353
2010 Niakan KK, Ji H, Maehr R, Vokes SA, Rodolfa KT, Sherwood RI, Yamaki M, Dimos JT, Chen AE, Melton DA, McMahon AP, Eggan K. Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal. Genes & Development. 24: 312-26. PMID 20123909 DOI: 10.1101/Gad.1833510  0.437
2010 Humphreys BD, Lin SL, Kobayashi A, Hudson TE, Nowlin BT, Bonventre JV, Valerius MT, McMahon AP, Duffield JS. Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. The American Journal of Pathology. 176: 85-97. PMID 20008127 DOI: 10.2353/Ajpath.2010.090517  0.396
2009 Shah A, Tenzen T, McMahon AP, Woolf PJ. Using mechanistic Bayesian networks to identify downstream targets of the sonic hedgehog pathway. Bmc Bioinformatics. 10: 433. PMID 20021670 DOI: 10.1186/1471-2105-10-433  0.372
2009 Ingham PW, McMahon AP. Hedgehog signalling: Kif7 is not that fishy after all. Current Biology : Cb. 19: R729-31. PMID 19906571 DOI: 10.1016/J.Cub.2009.07.060  0.376
2009 Tsiairis CD, McMahon AP. An Hh-dependent pathway in lateral plate mesoderm enables the generation of left/right asymmetry. Current Biology : Cb. 19: 1912-7. PMID 19879143 DOI: 10.1016/J.Cub.2009.09.057  0.79
2009 Mugford JW, Yu J, Kobayashi A, McMahon AP. High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population. Developmental Biology. 333: 312-23. PMID 19591821 DOI: 10.1016/J.Ydbio.2009.06.043  0.793
2009 Georgas K, Rumballe B, Valerius MT, Chiu HS, Thiagarajan RD, Lesieur E, Aronow BJ, Brunskill EW, Combes AN, Tang D, Taylor D, Grimmond SM, Potter SS, McMahon AP, Little MH. Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Developmental Biology. 332: 273-86. PMID 19501082 DOI: 10.1016/J.Ydbio.2009.05.578  0.451
2009 Hofmann I, Stover EH, Cullen DE, Mao J, Morgan KJ, Lee BH, Kharas MG, Miller PG, Cornejo MG, Okabe R, Armstrong SA, Ghilardi N, Gould S, de Sauvage FJ, McMahon AP, et al. Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis. Cell Stem Cell. 4: 559-67. PMID 19497284 DOI: 10.1016/J.Stem.2009.03.016  0.438
2009 Nishi Y, Ji H, Wong WH, McMahon AP, Vokes SA. Modeling the spatio-temporal network that drives patterning in the vertebrate central nervous system. Biochimica Et Biophysica Acta. 1789: 299-305. PMID 19445894 DOI: 10.1016/J.Bbagrm.2009.01.002  0.428
2009 Mao J, McGlinn E, Huang P, Tabin CJ, McMahon AP. Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limb. Developmental Cell. 16: 600-6. PMID 19386268 DOI: 10.1016/J.Devcel.2009.02.005  0.416
2009 Agalliu D, Takada S, Agalliu I, McMahon AP, Jessell TM. Motor neurons with axial muscle projections specified by Wnt4/5 signaling. Neuron. 61: 708-20. PMID 19285468 DOI: 10.1016/J.Neuron.2008.12.026  0.311
2009 Wang Y, Zhou Z, Walsh CT, McMahon AP. Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation. Proceedings of the National Academy of Sciences of the United States of America. 106: 2623-8. PMID 19196978 DOI: 10.1073/Pnas.0812110106  0.397
2009 Yu J, Carroll TJ, Rajagopal J, Kobayashi A, Ren Q, McMahon AP. A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney. Development (Cambridge, England). 136: 161-71. PMID 19060336 DOI: 10.1242/Dev.022087  0.489
2009 Kronenberg HM, McMahon AP, Tabin CJ. 6 Growth Factors and Chondrogenesis Cold Spring Harbor Monograph Archive. 53: 171-203. DOI: 10.1101/087969825.53.171  0.406
2009 Brunskill EW, Aronow BJ, Georgas K, Rumballe B, Valerius MT, Aronow J, Kaimal V, Jegga AG, Yu J, Grimmond S, McMahon AP, Patterson LT, Little MH, Potter SS. Atlas of Gene Expression in the Developing Kidney at Microanatomic Resolution (DOI:10.1016/j.devcel.2008.09.007) Developmental Cell. 16: 482. DOI: 10.1016/J.Devcel.2009.02.014  0.35
2008 Stenman JM, Rajagopal J, Carroll TJ, Ishibashi M, McMahon J, McMahon AP. Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature. Science (New York, N.Y.). 322: 1247-50. PMID 19023080 DOI: 10.1126/Science.1164594  0.361
2008 Brunskill EW, Aronow BJ, Georgas K, Rumballe B, Valerius MT, Aronow J, Kaimal V, Jegga AG, Yu J, Grimmond S, McMahon AP, Patterson LT, Little MH, Potter SS. Atlas of gene expression in the developing kidney at microanatomic resolution. Developmental Cell. 15: 781-91. PMID 19000842 DOI: 10.1016/J.Devcel.2008.09.007  0.452
2008 Wu JY, Purton LE, Rodda SJ, Chen M, Weinstein LS, McMahon AP, Scadden DT, Kronenberg HM. Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathways. Proceedings of the National Academy of Sciences of the United States of America. 105: 16976-81. PMID 18957542 DOI: 10.1073/Pnas.0802898105  0.313
2008 Mugford JW, Sipilä P, McMahon JA, McMahon AP. Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney. Developmental Biology. 324: 88-98. PMID 18835385 DOI: 10.1016/J.Ydbio.2008.09.010  0.792
2008 Vokes SA, Ji H, Wong WH, McMahon AP. A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb. Genes & Development. 22: 2651-63. PMID 18832070 DOI: 10.1101/Gad.1693008  0.408
2008 Schüller U, Heine VM, Mao J, Kho AT, Dillon AK, Han YG, Huillard E, Sun T, Ligon AH, Qian Y, Ma Q, Alvarez-Buylla A, McMahon AP, Rowitch DH, Ligon KL. Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma. Cancer Cell. 14: 123-34. PMID 18691547 DOI: 10.1016/J.Ccr.2008.07.005  0.807
2008 Kobayashi A, Valerius MT, Mugford JW, Carroll TJ, Self M, Oliver G, McMahon AP. Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development. Cell Stem Cell. 3: 169-81. PMID 18682239 DOI: 10.1016/J.Stem.2008.05.020  0.8
2008 Tabin CJ, McMahon AP. Developmental biology. Grasping limb patterning. Science (New York, N.Y.). 321: 350-2. PMID 18635784 DOI: 10.1126/Science.1162474  0.374
2008 Dessaud E, McMahon AP, Briscoe J. Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network. Development (Cambridge, England). 135: 2489-503. PMID 18621990 DOI: 10.1242/Dev.009324  0.392
2008 Dakubo GD, Mazerolle C, Furimsky M, Yu C, St-Jacques B, McMahon AP, Wallace VA. Indian hedgehog signaling from endothelial cells is required for sclera and retinal pigment epithelium development in the mouse eye. Developmental Biology. 320: 242-55. PMID 18582859 DOI: 10.1016/J.Ydbio.2008.05.528  0.476
2008 Walkley CR, Qudsi R, Sankaran VG, Perry JA, Gostissa M, Roth SI, Rodda SJ, Snay E, Dunning P, Fahey FH, Alt FW, McMahon AP, Orkin SH. Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease. Genes & Development. 22: 1662-76. PMID 18559481 DOI: 10.1101/Gad.1656808  0.322
2008 Shimada M, Greer PA, McMahon AP, Bouxsein ML, Schipani E. In vivo targeted deletion of calpain small subunit, Capn4, in cells of the osteoblast lineage impairs cell proliferation, differentiation, and bone formation. The Journal of Biological Chemistry. 283: 21002-10. PMID 18515801 DOI: 10.1074/Jbc.M710354200  0.35
2008 Mugford JW, Sipilä P, Kobayashi A, Behringer RR, McMahon AP. Hoxd11 specifies a program of metanephric kidney development within the intermediate mesoderm of the mouse embryo. Developmental Biology. 319: 396-405. PMID 18485340 DOI: 10.1016/J.Ydbio.2008.03.044  0.785
2008 Tsiairis CD, McMahon AP. Disp1 regulates growth of mammalian long bones through the control of Ihh distribution. Developmental Biology. 317: 480-5. PMID 18395198 DOI: 10.1016/J.Ydbio.2008.02.039  0.794
2008 Humphreys BD, Valerius MT, Kobayashi A, Mugford JW, Soeung S, Duffield JS, McMahon AP, Bonventre JV. Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell. 2: 284-91. PMID 18371453 DOI: 10.1016/J.Stem.2008.01.014  0.764
2008 Rajagopal J, Carroll TJ, Guseh JS, Bores SA, Blank LJ, Anderson WJ, Yu J, Zhou Q, McMahon AP, Melton DA. Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme. Development (Cambridge, England). 135: 1625-34. PMID 18367557 DOI: 10.1242/Dev.015495  0.413
2008 Valerius MT, McMahon AP. Transcriptional profiling of Wnt4 mutant mouse kidneys identifies genes expressed during nephron formation. Gene Expression Patterns : Gep. 8: 297-306. PMID 18346943 DOI: 10.1016/J.Gep.2008.02.001  0.429
2008 McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P. GUDMAP: the genitourinary developmental molecular anatomy project. Journal of the American Society of Nephrology : Jasn. 19: 667-71. PMID 18287559 DOI: 10.1681/Asn.2007101078  0.348
2008 Chamberlain CE, Jeong J, Guo C, Allen BL, McMahon AP. Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning. Development (Cambridge, England). 135: 1097-106. PMID 18272593 DOI: 10.1242/Dev.013086  0.753
2008 Kobayashi T, Lu J, Cobb BS, Rodda SJ, McMahon AP, Schipani E, Merkenschlager M, Kronenberg HM. Dicer-dependent pathways regulate chondrocyte proliferation and differentiation. Proceedings of the National Academy of Sciences of the United States of America. 105: 1949-54. PMID 18238902 DOI: 10.1073/Pnas.0707900105  0.352
2008 Marose TD, Merkel CE, McMahon AP, Carroll TJ. Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state. Developmental Biology. 314: 112-26. PMID 18177851 DOI: 10.1016/J.Ydbio.2007.11.016  0.439
2008 Tian H, Jeong J, Harfe BD, Tabin CJ, McMahon AP. Erratum: Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand (Development vol. 132 (133-142)) Development. 135: 3471-3472. DOI: 10.1242/Dev.029678  0.557
2008 Zhang IH, Stover EH, Cullen DE, Mao J, Morgan KJ, Lee BH, Kharas MG, Miller PG, Okabe R, Armstrong SA, Ghilardi N, Gould S, deSauvage FJ, McMahon AP, Gilliland DG. Hedgehog Signaling Is Dispensable for Adult Murine Hematopoiesis and Leukemogenesis. Blood. 112: 1391-1391. DOI: 10.1182/blood.v112.11.1391.1391  0.36
2007 Barrow JR, Howell WD, Rule M, Hayashi S, Thomas KR, Capecchi MR, McMahon AP. Wnt3 signaling in the epiblast is required for proper orientation of the anteroposterior axis. Developmental Biology. 312: 312-20. PMID 18028899 DOI: 10.1016/J.Ydbio.2007.09.030  0.446
2007 Wingert RA, Selleck R, Yu J, Song HD, Chen Z, Song A, Zhou Y, Thisse B, Thisse C, McMahon AP, Davidson AJ. The cdx genes and retinoic acid control the positioning and segmentation of the zebrafish pronephros. Plos Genetics. 3: 1922-38. PMID 17953490 DOI: 10.1371/Journal.Pgen.0030189  0.328
2007 Kim BM, Miletich I, Mao J, McMahon AP, Sharpe PA, Shivdasani RA. Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen. Development (Cambridge, England). 134: 3603-13. PMID 17855428 DOI: 10.1242/Dev.009308  0.511
2007 Zhou W, Lin L, Majumdar A, Li X, Zhang X, Liu W, Etheridge L, Shi Y, Martin J, Van de Ven W, Kaartinen V, Wynshaw-Boris A, McMahon AP, Rosenfeld MG, Evans SM. Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2. Nature Genetics. 39: 1225-34. PMID 17767158 DOI: 10.1038/Ng2112  0.432
2007 Abzhanov A, Rodda SJ, McMahon AP, Tabin CJ. Regulation of skeletogenic differentiation in cranial dermal bone. Development (Cambridge, England). 134: 3133-44. PMID 17670790 DOI: 10.1242/Dev.002709  0.396
2007 Park JS, Valerius MT, McMahon AP. Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development. Development (Cambridge, England). 134: 2533-9. PMID 17537789 DOI: 10.1242/Dev.006155  0.593
2007 Allen BL, Tenzen T, McMahon AP. The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development. Genes & Development. 21: 1244-57. PMID 17504941 DOI: 10.1101/Gad.1543607  0.685
2007 Little MH, Brennan J, Georgas K, Davies JA, Davidson DR, Baldock RA, Beverdam A, Bertram JF, Capel B, Chiu HS, Clements D, Cullen-McEwen L, Fleming J, Gilbert T, Herzlinger D, ... ... McMahon AP, et al. A high-resolution anatomical ontology of the developing murine genitourinary tract. Gene Expression Patterns : Gep. 7: 680-99. PMID 17452023 DOI: 10.1016/J.Modgep.2007.03.002  0.356
2007 Vokes SA, Ji H, McCuine S, Tenzen T, Giles S, Zhong S, Longabaugh WJ, Davidson EH, Wong WH, McMahon AP. Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning. Development (Cambridge, England). 134: 1977-89. PMID 17442700 DOI: 10.1242/Dev.001966  0.541
2007 Wang Y, McMahon AP, Allen BL. Shifting paradigms in Hedgehog signaling. Current Opinion in Cell Biology. 19: 159-65. PMID 17303409 DOI: 10.1016/J.Ceb.2007.02.005  0.637
2007 Cheng HT, Kim M, Valerius MT, Surendran K, Schuster-Gossler K, Gossler A, McMahon AP, Kopan R. Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron. Development (Cambridge, England). 134: 801-11. PMID 17229764 DOI: 10.1242/Dev.02773  0.46
2007 Tu X, Joeng KS, Nakayama KI, Nakayama K, Rajagopal J, Carroll TJ, McMahon AP, Long F. Noncanonical Wnt signaling through G protein-linked PKCdelta activation promotes bone formation. Developmental Cell. 12: 113-27. PMID 17199045 DOI: 10.1016/J.Devcel.2006.11.003  0.465
2007 Gritli-Linde A, Hallberg K, Harfe BD, Reyahi A, Kannius-Janson M, Nilsson J, Cobourne MT, Sharpe PT, McMahon AP, Linde A. Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling. Developmental Cell. 12: 99-112. PMID 17199044 DOI: 10.1016/J.Devcel.2006.12.006  0.457
2007 McGlinn E, Mao J, Nissim S, McMahon A, Tabin C. Novel molecular mechanisms regulating Shh expression and limb patterning The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A199-C  0.366
2007 McMahon AP, Merkel CE, Marose TD, Carroll TJ. WITHDRAWN: Loss ofβ-catenin results in premature differentiation and extrusion of Wolffian duct epithelia Developmental Biology. 306: 414. DOI: 10.1016/J.Ydbio.2007.03.287  0.32
2007 Little MH, Brennan J, Georgas K, Davies JA, Davidson DR, Baldock RA, Beverdam A, Bertram JF, Capel B, Chiu HS, Clements D, Cullen-McEwen L, Fleming J, Gilbert T, Herzlinger D, ... ... McMahon AP, et al. Corrigendum to "A high-resolution anatomical ontology of the developing murine genitourinary tract" [Gene Expression Patterns 7 (2007) 680-699] (DOI:10.1016/j.modgep.2007.03.002) Gene Expression Patterns. 8: 47-50. DOI: 10.1016/J.Modgep.2007.07.003  0.345
2006 Mao J, Ligon KL, Rakhlin EY, Thayer SP, Bronson RT, Rowitch D, McMahon AP. A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway. Cancer Research. 66: 10171-8. PMID 17047082 DOI: 10.1158/0008-5472.Can-06-0657  0.573
2006 Long F, Joeng KS, Xuan S, Efstratiadis A, McMahon AP. Independent regulation of skeletal growth by Ihh and IGF signaling. Developmental Biology. 298: 327-33. PMID 16905129 DOI: 10.1016/J.Ydbio.2006.06.042  0.339
2006 Rodda SJ, McMahon AP. Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors. Development (Cambridge, England). 133: 3231-44. PMID 16854976 DOI: 10.1242/Dev.02480  0.435
2006 Yu J, McMahon AP. Reproducible and inducible knockdown of gene expression in mice. Genesis (New York, N.Y. : 2000). 44: 252-61. PMID 16676321 DOI: 10.1002/Dvg.20213  0.379
2006 Tenzen T, Allen BL, Cole F, Kang JS, Krauss RS, McMahon AP. The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice. Developmental Cell. 10: 647-56. PMID 16647304 DOI: 10.1016/J.Devcel.2006.04.004  0.69
2006 Vokes SA, Ji H, Wong WH, McMahon AP. A tale of two morphogen gradients: Identifying Gli targets of Hedgehog Signaling Developmental Biology. 295: 423. DOI: 10.1016/J.Ydbio.2006.04.301  0.356
2005 Kobayashi T, Lyons KM, McMahon AP, Kronenberg HM. BMP signaling stimulates cellular differentiation at multiple steps during cartilage development. Proceedings of the National Academy of Sciences of the United States of America. 102: 18023-7. PMID 16322106 DOI: 10.1073/Pnas.0503617102  0.467
2005 Nybakken K, Vokes SA, Lin TY, McMahon AP, Perrimon N. A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway. Nature Genetics. 37: 1323-32. PMID 16311596 DOI: 10.1038/Ng1682  0.402
2005 Mao J, Barrow J, McMahon J, Vaughan J, McMahon AP. An ES cell system for rapid, spatial and temporal analysis of gene function in vitro and in vivo. Nucleic Acids Research. 33: e155. PMID 16221970 DOI: 10.1093/Nar/Gni146  0.443
2005 Batourina E, Tsai S, Lambert S, Sprenkle P, Viana R, Dutta S, Hensle T, Wang F, Niederreither K, McMahon AP, Carroll TJ, Mendelsohn CL. Apoptosis induced by vitamin A signaling is crucial for connecting the ureters to the bladder. Nature Genetics. 37: 1082-9. PMID 16186816 DOI: 10.1038/Ng1645  0.369
2005 Lobov IB, Rao S, Carroll TJ, Vallance JE, Ito M, Ondr JK, Kurup S, Glass DA, Patel MS, Shu W, Morrisey EE, McMahon AP, Karsenty G, Lang RA. WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature. Nature. 437: 417-21. PMID 16163358 DOI: 10.1038/Nature03928  0.364
2005 Wijgerde M, Karp S, McMahon J, McMahon AP. Noggin antagonism of BMP4 signaling controls development of the axial skeleton in the mouse. Developmental Biology. 286: 149-57. PMID 16122729 DOI: 10.1016/J.Ydbio.2005.07.016  0.476
2005 Vaziri Sani F, Hallberg K, Harfe BD, McMahon AP, Linde A, Gritli-Linde A. Fate-mapping of the epithelial seam during palatal fusion rules out epithelial-mesenchymal transformation. Developmental Biology. 285: 490-5. PMID 16109396 DOI: 10.1016/J.Ydbio.2005.07.027  0.371
2005 Carroll TJ, Park JS, Hayashi S, Majumdar A, McMahon AP. Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Developmental Cell. 9: 283-92. PMID 16054034 DOI: 10.1016/J.Devcel.2005.05.016  0.643
2005 Matsuoka T, Ahlberg PE, Kessaris N, Iannarelli P, Dennehy U, Richardson WD, McMahon AP, Koentges G. Neural crest origins of the neck and shoulder. Nature. 436: 347-55. PMID 16034409 DOI: 10.1038/Nature03837  0.352
2005 Kobayashi T, Soegiarto DW, Yang Y, Lanske B, Schipani E, McMahon AP, Kronenberg HM. Indian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrP. The Journal of Clinical Investigation. 115: 1734-42. PMID 15951842 DOI: 10.1172/Jci24397  0.395
2005 Kobayashi A, Kwan KM, Carroll TJ, McMahon AP, Mendelsohn CL, Behringer RR. Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development. Development (Cambridge, England). 132: 2809-23. PMID 15930111 DOI: 10.1242/Dev.01858  0.415
2005 Glass DA, Bialek P, Ahn JD, Starbuck M, Patel MS, Clevers H, Taketo MM, Long F, McMahon AP, Lang RA, Karsenty G. Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Developmental Cell. 8: 751-64. PMID 15866165 DOI: 10.1016/J.Devcel.2005.02.017  0.371
2005 Ellis P, Fagan BM, Magness ST, Hutton S, Taranova O, Hayashi S, McMahon A, Rao M, Pevny L. SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult. Developmental Neuroscience. 26: 148-65. PMID 15711057 DOI: 10.1159/000082134  0.432
2005 Basson MA, Akbulut S, Watson-Johnson J, Simon R, Carroll TJ, Shakya R, Gross I, Martin GR, Lufkin T, McMahon AP, Wilson PD, Costantini FD, Mason IJ, Licht JD. Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction. Developmental Cell. 8: 229-39. PMID 15691764 DOI: 10.1016/J.Devcel.2004.12.004  0.457
2005 Tian H, Jeong J, Harfe BD, Tabin CJ, McMahon AP. Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand. Development (Cambridge, England). 132: 133-42. PMID 15576405 DOI: 10.1242/Dev.01563  0.626
2005 Jeong J, McMahon AP. Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1. Development (Cambridge, England). 132: 143-54. PMID 15576403 DOI: 10.1242/Dev.01566  0.614
2005 Mcmahon AP. Patterning of the mammalian kidney Kidney International. 68: 1962. DOI: 10.1038/Ki.2005.12  0.4
2004 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, ... ... McMahon AP, et al. Mouse brain organization revealed through direct genome-scale TF expression analysis. Science (New York, N.Y.). 306: 2255-7. PMID 15618518 DOI: 10.1126/Science.1104935  0.561
2004 Yu J, McMahon AP, Valerius MT. Recent genetic studies of mouse kidney development. Current Opinion in Genetics & Development. 14: 550-7. PMID 15380247 DOI: 10.1016/J.Gde.2004.07.009  0.45
2004 Fuccillo M, Rallu M, McMahon AP, Fishell G. Temporal requirement for hedgehog signaling in ventral telencephalic patterning. Development (Cambridge, England). 131: 5031-40. PMID 15371303 DOI: 10.1242/Dev.01349  0.46
2004 Vokes SA, McMahon AP. Hedgehog signaling: iguana debuts as a nuclear gatekeeper. Current Biology : Cb. 14: R668-70. PMID 15324687 DOI: 10.1016/J.Cub.2004.08.015  0.41
2004 Harfe BD, Scherz PJ, Nissim S, Tian H, McMahon AP, Tabin CJ. Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities. Cell. 118: 517-28. PMID 15315763 DOI: 10.1016/J.Cell.2004.07.024  0.393
2004 Vokes SA, Yatskievych TA, Heimark RL, McMahon J, McMahon AP, Antin PB, Krieg PA. Hedgehog signaling is essential for endothelial tube formation during vasculogenesis. Development (Cambridge, England). 131: 4371-80. PMID 15294868 DOI: 10.1242/Dev.01304  0.36
2004 Tian H, Tenzen T, McMahon AP. Dose dependency of Disp1 and genetic interaction between Disp1 and other hedgehog signaling components in the mouse. Development (Cambridge, England). 131: 4021-33. PMID 15269168 DOI: 10.1242/Dev.01257  0.46
2004 Scherz PJ, Harfe BD, McMahon AP, Tabin CJ. The limb bud Shh-Fgf feedback loop is terminated by expansion of former ZPA cells. Science (New York, N.Y.). 305: 396-9. PMID 15256670 DOI: 10.1126/Science.1096966  0.477
2004 Rice R, Spencer-Dene B, Connor EC, Gritli-Linde A, McMahon AP, Dickson C, Thesleff I, Rice DP. Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate. The Journal of Clinical Investigation. 113: 1692-700. PMID 15199404 DOI: 10.1172/Jci20384  0.479
2004 Lewis PM, Gritli-Linde A, Smeyne R, Kottmann A, McMahon AP. Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum. Developmental Biology. 270: 393-410. PMID 15183722 DOI: 10.1016/J.Ydbio.2004.03.007  0.482
2004 Jeong J, Mao J, Tenzen T, Kottmann AH, McMahon AP. Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia. Genes & Development. 18: 937-51. PMID 15107405 DOI: 10.1101/Gad.1190304  0.653
2004 Cowan CA, Klimanskaya I, McMahon J, Atienza J, Witmyer J, Zucker JP, Wang S, Morton CC, McMahon AP, Powers D, Melton DA. Derivation of embryonic stem-cell lines from human blastocysts. The New England Journal of Medicine. 350: 1353-6. PMID 14999088 DOI: 10.1056/Nejmsr040330  0.332
2004 Long F, Chung UI, Ohba S, McMahon J, Kronenberg HM, McMahon AP. Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton. Development (Cambridge, England). 131: 1309-18. PMID 14973297 DOI: 10.1242/Dev.01006  0.386
2003 Hayashi S, Tenzen T, McMahon AP. Maternal inheritance of Cre activity in a Sox2Cre deleter strain. Genesis (New York, N.Y. : 2000). 37: 51-3. PMID 14595839 DOI: 10.1002/Gene.10225  0.34
2003 Clement AM, Nguyen MD, Roberts EA, Garcia ML, Boillée S, Rule M, McMahon AP, Doucette W, Siwek D, Ferrante RJ, Brown RH, Julien JP, Goldstein LS, Cleveland DW. Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science (New York, N.Y.). 302: 113-7. PMID 14526083 DOI: 10.1126/Science.1086071  0.3
2003 Machold R, Hayashi S, Rutlin M, Muzumdar MD, Nery S, Corbin JG, Gritli-Linde A, Dellovade T, Porter JA, Rubin LL, Dudek H, McMahon AP, Fishell G. Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches. Neuron. 39: 937-50. PMID 12971894 DOI: 10.1016/S0896-6273(03)00561-0  0.467
2003 Kawahira H, Ma NH, Tzanakakis ES, McMahon AP, Chuang PT, Hebrok M. Combined activities of hedgehog signaling inhibitors regulate pancreas development. Development (Cambridge, England). 130: 4871-9. PMID 12917290 DOI: 10.1242/Dev.00653  0.496
2003 Majumdar A, Vainio S, Kispert A, McMahon J, McMahon AP. Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development. Development (Cambridge, England). 130: 3175-85. PMID 12783789 DOI: 10.1242/Dev.00520  0.516
2003 Dakubo GD, Wang YP, Mazerolle C, Campsall K, McMahon AP, Wallace VA. Retinal ganglion cell-derived sonic hedgehog signaling is required for optic disc and stalk neuroepithelial cell development. Development (Cambridge, England). 130: 2967-80. PMID 12756179 DOI: 10.1242/Dev.00515  0.373
2003 Trokovic R, Trokovic N, Hernesniemi S, Pirvola U, Vogt Weisenhorn DM, Rossant J, McMahon AP, Wurst W, Partanen J. FGFR1 is independently required in both developing mid- and hindbrain for sustained response to isthmic signals. The Embo Journal. 22: 1811-23. PMID 12682014 DOI: 10.1093/Emboj/Cdg169  0.476
2003 Charron F, Stein E, Jeong J, McMahon AP, Tessier-Lavigne M. The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance. Cell. 113: 11-23. PMID 12679031 DOI: 10.1016/S0092-8674(03)00199-5  0.466
2003 Ligon KL, Echelard Y, Assimacopoulos S, Danielian PS, Kaing S, Grove EA, McMahon AP, Rowitch DH. Loss of Emx2 function leads to ectopic expression of Wnt1 in the developing telencephalon and cortical dysplasia. Development (Cambridge, England). 130: 2275-87. PMID 12668639 DOI: 10.1242/Dev.00421  0.627
2003 Barrow JR, Thomas KR, Boussadia-Zahui O, Moore R, Kemler R, Capecchi MR, McMahon AP. Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge. Genes & Development. 17: 394-409. PMID 12569130 DOI: 10.1101/Gad.1044903  0.41
2003 Chuang PT, Kawcak T, McMahon AP. Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung. Genes & Development. 17: 342-7. PMID 12569124 DOI: 10.1101/Gad.1026303  0.435
2003 Chuang PT, McMahon AP. Branching morphogenesis of the lung: new molecular insights into an old problem. Trends in Cell Biology. 13: 86-91. PMID 12559759 DOI: 10.1016/S0962-8924(02)00031-4  0.393
2003 McMahon AP, Ingham PW, Tabin CJ. Developmental roles and clinical significance of hedgehog signaling. Current Topics in Developmental Biology. 53: 1-114. PMID 12509125 DOI: 10.1016/S0070-2153(03)53002-2  0.421
2002 Hayashi S, Lewis P, Pevny L, McMahon AP. Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain. Mechanisms of Development. 119: S97-S101. PMID 14516668 DOI: 10.1016/S0925-4773(03)00099-6  0.387
2002 Hayashi S, Lewis P, Pevny L, McMahon AP. Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain. Gene Expression Patterns : Gep. 2: 93-7. PMID 12617844 DOI: 10.1016/S0925-4773(02)00292-7  0.389
2002 Wijgerde M, McMahon JA, Rule M, McMahon AP. A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord. Genes & Development. 16: 2849-64. PMID 12435628 DOI: 10.1101/Gad.1025702  0.459
2002 Gritli-Linde A, Bei M, Maas R, Zhang XM, Linde A, McMahon AP. Shh signaling within the dental epithelium is necessary for cell proliferation, growth and polarization. Development (Cambridge, England). 129: 5323-37. PMID 12403705 DOI: 10.1242/Dev.00100  0.481
2002 Yu J, Carroll TJ, McMahon AP. Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney. Development (Cambridge, England). 129: 5301-12. PMID 12399320  0.414
2002 Rallu M, Machold R, Gaiano N, Corbin JG, McMahon AP, Fishell G. Dorsoventral patterning is established in the telencephalon of mutants lacking both Gli3 and Hedgehog signaling. Development (Cambridge, England). 129: 4963-74. PMID 12397105  0.376
2002 Ishibashi M, McMahon AP. A sonic hedgehog-dependent signaling relay regulates growth of diencephalic and mesencephalic primordia in the early mouse embryo. Development (Cambridge, England). 129: 4807-19. PMID 12361972  0.382
2002 Jeong J, McMahon AP. Cholesterol modification of Hedgehog family proteins. The Journal of Clinical Investigation. 110: 591-6. PMID 12208857 DOI: 10.1172/Jci16506  0.662
2002 Wang YP, Dakubo G, Howley P, Campsall KD, Mazarolle CJ, Shiga SA, Lewis PM, McMahon AP, Wallace VA. Development of normal retinal organization depends on Sonic hedgehog signaling from ganglion cells. Nature Neuroscience. 5: 831-2. PMID 12195432 DOI: 10.1038/Nn911  0.344
2002 Zirlinger M, Lo L, McMahon J, McMahon AP, Anderson DJ. Transient expression of the bHLH factor neurogenin-2 marks a subpopulation of neural crest cells biased for a sensory but not a neuronal fate. Proceedings of the National Academy of Sciences of the United States of America. 99: 8084-9. PMID 12060754 DOI: 10.1073/Pnas.122231199  0.381
2002 Megason SG, McMahon AP. A mitogen gradient of dorsal midline Wnts organizes growth in the CNS. Development (Cambridge, England). 129: 2087-98. PMID 11959819  0.69
2002 Hayashi S, McMahon AP. Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. Developmental Biology. 244: 305-18. PMID 11944939 DOI: 10.1006/Dbio.2002.0597  0.404
2002 Mulroy T, McMahon JA, Burakoff SJ, McMahon AP, Sen J. Wnt-1 and Wnt-4 regulate thymic cellularity. European Journal of Immunology. 32: 967-71. PMID 11920562 DOI: 10.1002/1521-4141(200204)32:4<967::Aid-Immu967>3.0.Co;2-6  0.492
2002 Heanue TA, Davis RJ, Rowitch DH, Kispert A, McMahon AP, Mardon G, Tabin CJ. Dach1, a vertebrate homologue of Drosophila dachshund, is expressed in the developing eye and ear of both chick and mouse and is regulated independently of Pax and Eya genes. Mechanisms of Development. 111: 75-87. PMID 11804780 DOI: 10.1016/S0925-4773(01)00611-6  0.587
2001 Long F, Zhang XM, Karp S, Yang Y, McMahon AP. Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. Development (Cambridge, England). 128: 5099-108. PMID 11748145  0.335
2001 Ingham PW, McMahon AP. Hedgehog signaling in animal development: paradigms and principles. Genes & Development. 15: 3059-87. PMID 11731473 DOI: 10.1101/Gad.938601  0.438
2001 Minina E, Wenzel HM, Kreschel C, Karp S, Gaffield W, McMahon AP, Vortkamp A. BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation. Development (Cambridge, England). 128: 4523-34. PMID 11714677  0.384
2001 Parr BA, Cornish VA, Cybulsky MI, McMahon AP. Wnt7b regulates placental development in mice. Developmental Biology. 237: 324-32. PMID 11543617 DOI: 10.1006/dbio.2001.0373  0.346
2001 Zhang XM, Ramalho-Santos M, McMahon AP. Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node. Cell. 106: 781-92. PMID 11517919 DOI: 10.1016/S0092-8674(01)00385-3  0.404
2001 Gritli-Linde A, Lewis P, McMahon AP, Linde A. The whereabouts of a morphogen: direct evidence for short- and graded long-range activity of hedgehog signaling peptides. Developmental Biology. 236: 364-86. PMID 11476578 DOI: 10.1006/Dbio.2001.0336  0.392
2001 Lagutin O, Zhu CC, Furuta Y, Rowitch DH, McMahon AP, Oliver G. Six3 promotes the formation of ectopic optic vesicle-like structures in mouse embryos. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 221: 342-9. PMID 11458394 DOI: 10.1002/Dvdy.1148  0.598
2001 Jeong J, McMahon AP. Developmental biology. Vesicles and the spinal cord. Nature. 412: 136-7. PMID 11449254 DOI: 10.1038/35084318  0.509
2001 Lewis PM, Dunn MP, McMahon JA, Logan M, Martin JF, St-Jacques B, McMahon AP. Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1. Cell. 105: 599-612. PMID 11389830 DOI: 10.1016/S0092-8674(01)00369-5  0.632
2001 Bonifas JM, Pennypacker S, Chuang PT, McMahon AP, Williams M, Rosenthal A, De Sauvage FJ, Epstein EH. Activation of expression of hedgehog target genes in basal cell carcinomas. The Journal of Investigative Dermatology. 116: 739-42. PMID 11348463 DOI: 10.1046/J.1523-1747.2001.01315.X  0.41
2001 Brault V, Moore R, Kutsch S, Ishibashi M, Rowitch DH, McMahon AP, Sommer L, Boussadia O, Kemler R. Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development (Cambridge, England). 128: 1253-64. PMID 11262227  0.521
2001 Chung UI, Schipani E, McMahon AP, Kronenberg HM. Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development. The Journal of Clinical Investigation. 107: 295-304. PMID 11160153 DOI: 10.1172/Jci11706  0.354
2001 Treier M, O'Connell S, Gleiberman A, Price J, Szeto DP, Burgess R, Chuang PT, McMahon AP, Rosenfeld MG. Hedgehog signaling is required for pituitary gland development. Development (Cambridge, England). 128: 377-86. PMID 11152636  0.405
2001 Kuschert S, Rowitch DH, Haenig B, McMahon AP, Kispert A. Characterization of Pax-2 regulatory sequences that direct transgene expression in the Wolffian duct and its derivatives. Developmental Biology. 229: 128-40. PMID 11133159 DOI: 10.1006/Dbio.2000.9971  0.614
2000 Hebrok M, Kim SK, St Jacques B, McMahon AP, Melton DA. Regulation of pancreas development by hedgehog signaling. Development (Cambridge, England). 127: 4905-13. PMID 11044404  0.349
2000 Dassule HR, Lewis P, Bei M, Maas R, McMahon AP. Sonic hedgehog regulates growth and morphogenesis of the tooth. Development (Cambridge, England). 127: 4775-85. PMID 11044393  0.806
2000 McMahon AP. Neural patterning: the role of Nkx genes in the ventral spinal cord. Genes & Development. 14: 2261-4. PMID 10995382 DOI: 10.1101/Gad.840800  0.409
2000 O'Shaughnessy PJ, Baker PJ, Heikkilä M, Vainio S, McMahon AP. Localization of 17beta-hydroxysteroid dehydrogenase/17-ketosteroid reductase isoform expression in the developing mouse testis--androstenedione is the major androgen secreted by fetal/neonatal leydig cells. Endocrinology. 141: 2631-7. PMID 10875268 DOI: 10.1210/Endo.141.7.7545  0.354
2000 Ramalho-Santos M, Melton DA, McMahon AP. Hedgehog signals regulate multiple aspects of gastrointestinal development. Development (Cambridge, England). 127: 2763-72. PMID 10821773  0.41
2000 Brisken C, Heineman A, Chavarria T, Elenbaas B, Tan J, Dey SK, McMahon JA, McMahon AP, Weinberg RA. Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling. Genes & Development. 14: 650-4. PMID 10733525 DOI: 10.1101/Gad.14.6.650  0.428
2000 Chai Y, Jiang X, Ito Y, Bringas P, Han J, Rowitch DH, Soriano P, McMahon AP, Sucov HM. Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis. Development (Cambridge, England). 127: 1671-9. PMID 10725243  0.591
2000 Jiang X, Rowitch DH, Soriano P, McMahon AP, Sucov HM. Fate of the mammalian cardiac neural crest. Development (Cambridge, England). 127: 1607-16. PMID 10725237  0.54
2000 Lu QR, Yuk D, Alberta JA, Zhu Z, Pawlitzky I, Chan J, McMahon AP, Stiles CD, Rowitch DH. Sonic hedgehog--regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system. Neuron. 25: 317-29. PMID 10719888 DOI: 10.1016/S0896-6273(00)80897-1  0.64
2000 Drossopoulou G, Lewis KE, Sanz-Ezquerro JJ, Nikbakht N, McMahon AP, Hofmann C, Tickle C. A model for anteroposterior patterning of the vertebrate limb based on sequential long- and short-range Shh signalling and Bmp signalling. Development (Cambridge, England). 127: 1337-48. PMID 10704381  0.317
2000 Bachiller D, Klingensmith J, Kemp C, Belo JA, Anderson RM, May SR, McMahon JA, McMahon AP, Harland RM, Rossant J, De Robertis EM. The organizer factors Chordin and Noggin are required for mouse forebrain development. Nature. 403: 658-61. PMID 10688202 DOI: 10.1038/35001072  0.335
2000 McMahon AP. More surprises in the Hedgehog signaling pathway. Cell. 100: 185-8. PMID 10660040 DOI: 10.1016/S0092-8674(00)81555-X  0.305
2000 Karp SJ, Schipani E, St-Jacques B, Hunzelman J, Kronenberg H, McMahon AP. Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone related-protein-dependent and -independent pathways. Development (Cambridge, England). 127: 543-8. PMID 10631175  0.343
2000 Huo L, Roessler E, Dutra A, Chuang P, McMahon AP, Muenke M. Determination of the chromosomal location and genomic structure of the Hedgehog-Interacting Protein gene, and analysis of its role in Holoprosencephaly Gene Function & Disease. 1: 119-127. DOI: 10.1002/1438-826X(200010)1:3/4<119::Aid-Gnfd119>3.0.Co;2-K  0.408
1999 Mirsky R, Parmantier E, McMahon AP, Jessen KR. Schwann Cell-Derived Desert Hedgehog Signals Nerve Sheath Formation. Annals of the New York Academy of Sciences. 883: 196-202. PMID 29086927 DOI: 10.1111/J.1749-6632.1999.Tb08582.X  0.383
1999 Yamaguchi TP, Takada S, Yoshikawa Y, Wu N, McMahon AP. T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification. Genes & Development. 13: 3185-90. PMID 10617567 DOI: 10.1101/Gad.13.24.3185  0.464
1999 Botchkarev VA, Botchkareva NV, Roth W, Nakamura M, Chen LH, Herzog W, Lindner G, McMahon JA, Peters C, Lauster R, McMahon AP, Paus R. Noggin is a mesenchymally derived stimulator of hair-follicle induction. Nature Cell Biology. 1: 158-64. PMID 10559902 DOI: 10.1038/11078  0.425
1999 Rowitch DH, Kispert A, McMahon AP. Pax-2 regulatory sequences that direct transgene expression in the developing neural plate and external granule cell layer of the cerebellum. Brain Research. Developmental Brain Research. 117: 99-108. PMID 10536237 DOI: 10.1016/S0165-3806(99)00104-2  0.625
1999 Zúñiga A, Haramis AP, McMahon AP, Zeller R. Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds. Nature. 401: 598-602. PMID 10524628 DOI: 10.1038/44157  0.461
1999 Rowitch DH, S-Jacques B, Lee SM, Flax JD, Snyder EY, McMahon AP. Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8954-65. PMID 10516314 DOI: 10.1523/Jneurosci.19-20-08954.1999  0.661
1999 Parmantier E, Lynn B, Lawson D, Turmaine M, Namini SS, Chakrabarti L, McMahon AP, Jessen KR, Mirsky R. Schwann cell-derived Desert hedgehog controls the development of peripheral nerve sheaths. Neuron. 23: 713-24. PMID 10482238 DOI: 10.1016/S0896-6273(01)80030-1  0.384
1999 St-Jacques B, Hammerschmidt M, McMahon AP. Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation. Genes & Development. 13: 2072-86. PMID 10465785 DOI: 10.1101/Gad.13.16.2072  0.656
1999 Rowitch DH, Danielian PS, McMahon AP, Zec N. Cystic malformation of the posterior cerebellar vermis in transgenic mice that ectopically express Engrailed-1, a homeodomain transcription factor. Teratology. 60: 22-8. PMID 10413335 DOI: 10.1002/(Sici)1096-9926(199907)60:1<22::Aid-Tera7>3.0.Co;2-6  0.596
1999 Oppenheim RW, Homma S, Marti E, Prevette D, Wang S, Yaginuma H, McMahon AP. Modulation of early but not later stages of programmed cell death in embryonic avian spinal cord by sonic hedgehog. Molecular and Cellular Neurosciences. 13: 348-61. PMID 10356297 DOI: 10.1006/Mcne.1999.0755  0.365
1999 Perrimon N, McMahon AP. Negative feedback mechanisms and their roles during pattern formation. Cell. 97: 13-6. PMID 10199398 DOI: 10.1016/S0092-8674(00)80710-2  0.438
1999 Chuang PT, McMahon AP. Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein. Nature. 397: 617-21. PMID 10050855 DOI: 10.1038/17611  0.425
1999 Yamaguchi TP, Bradley A, McMahon AP, Jones S. A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development (Cambridge, England). 126: 1211-23. PMID 10021340  0.386
1999 Vainio S, Heikkilä M, Kispert A, Chin N, McMahon AP. Female development in mammals is regulated by Wnt-4 signalling. Nature. 397: 405-9. PMID 9989404 DOI: 10.1038/17068  0.359
1999 Rossant J, McMahon A. Cre -Ating Mouse Mutants : A Meeting Review On Conditional Mouse Genetics Genes & Development. 13: 142-145. PMID 9925637 DOI: 10.1101/Gad.13.2.142  0.398
1999 Epstein DJ, McMahon AP, Joyner AL. Regionalization of Sonic hedgehog transcription along the anteroposterior axis of the mouse central nervous system is regulated by Hnf3-dependent and -independent mechanisms. Development (Cambridge, England). 126: 281-92. PMID 9847242  0.33
1999 Hofmann C, Drossopoulou G, McMahon A, Balling R, Tickle C. Inhibitory action of BMPs on Pax1 expression and on shoulder girdle formation during limb development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 213: 199-206. PMID 9786420 DOI: 10.1002/(Sici)1097-0177(199810)213:2<199::Aid-Aja5>3.0.Co;2-B  0.411
1998 Danielian PS, Muccino D, Rowitch DH, Michael SK, McMahon AP. Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase. Current Biology : Cb. 8: 1323-6. PMID 9843687 DOI: 10.1016/S0960-9822(07)00562-3  0.587
1998 Parr BA, McMahon AP. Sexually dimorphic development of the mammalian reproductive tract requires Wnt-7a. Nature. 395: 707-10. PMID 9790192 DOI: 10.1038/27221  0.319
1998 Dassule HR, McMahon AP. Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth. Developmental Biology. 202: 215-27. PMID 9769173 DOI: 10.1006/Dbio.1998.8992  0.816
1998 Pepicelli CV, Lewis PM, McMahon AP. Sonic hedgehog regulates branching morphogenesis in the mammalian lung. Current Biology : Cb. 8: 1083-6. PMID 9768363 DOI: 10.1016/S0960-9822(98)70446-4  0.363
1998 St-Jacques B, Dassule HR, Karavanova I, Botchkarev VA, Li J, Danielian PS, McMahon JA, Lewis PM, Paus R, McMahon AP. Sonic hedgehog signaling is essential for hair development. Current Biology : Cb. 8: 1058-68. PMID 9768360 DOI: 10.1016/S0960-9822(98)70443-9  0.802
1998 Kispert A, Vainio S, McMahon AP. Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney. Development (Cambridge, England). 125: 4225-34. PMID 9753677  0.373
1998 Yang Y, Guillot P, Boyd Y, Lyon MF, McMahon AP. Evidence that preaxial polydactyly in the Doublefoot mutant is due to ectopic Indian Hedgehog signaling. Development (Cambridge, England). 125: 3123-32. PMID 9671585  0.307
1998 Chai N, Patel Y, Jacobson K, McMahon J, McMahon A, Rappolee DA. FGF is an essential regulator of the fifth cell division in preimplantation mouse embryos Developmental Biology. 198: 105-115. PMID 9640334 DOI: 10.1006/Dbio.1997.8858  0.447
1998 Rowitch DH, Echelard Y, Danielian PS, Gellner K, Brenner S, McMahon AP. Identification of an evolutionarily conserved 110 base-pair cis-acting regulatory sequence that governs Wnt-1 expression in the murine neural plate. Development (Cambridge, England). 125: 2735-46. PMID 9636087  0.606
1998 Treier M, Gleiberman AS, O'Connell SM, Szeto DP, McMahon JA, McMahon AP, Rosenfeld MG. Multistep signaling requirements for pituitary organogenesis in vivo. Genes & Development. 12: 1691-704. PMID 9620855 DOI: 10.1101/Gad.12.11.1691  0.487
1998 Brunet LJ, McMahon JA, McMahon AP, Harland RM. Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton. Science (New York, N.Y.). 280: 1455-7. PMID 9603738 DOI: 10.1126/Science.280.5368.1455  0.378
1998 McMahon JA, Takada S, Zimmerman LB, Fan CM, Harland RM, McMahon AP. Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite. Genes & Development. 12: 1438-52. PMID 9585504 DOI: 10.1101/Gad.12.10.1438  0.494
1998 Hammerschmidt M, McMahon AP. The effect of pertussis toxin on zebrafish development: a possible role for inhibitory G-proteins in hedgehog signaling. Developmental Biology. 194: 166-71. PMID 9501021 DOI: 10.1006/Dbio.1997.8796  0.674
1998 Rowitch DH, Danielian PS, McMahon AP, Zec N. Dandy-Walker Malformation in Transgenic Mice That Ectopically Express Engrailed-1, A Homeodomain Transcription Factor, in the Embryonic Brain • 302 Pediatric Research. 43: 54-54. DOI: 10.1203/00006450-199804001-00323  0.593
1997 Tabin CJ, McMahon AP. Recent advances in hedgehog signalling. Trends in Cell Biology. 7: 442-6. PMID 17709003 DOI: 10.1016/S0962-8924(97)01159-8  0.419
1997 Rowitch DH, Danielian PS, Lee SM, Echelard Y, McMahon AP. Cell interactions in patterning the mammalian midbrain. Cold Spring Harbor Symposia On Quantitative Biology. 62: 535-44. PMID 9598387 DOI: 10.1101/Sqb.1997.062.01.060  0.547
1997 Rauch GJ, Hammerschmidt M, Blader P, Schauerte HE, Strähle U, Ingham PW, McMahon AP, Haffter P. Wnt5 is required for tail formation in the zebrafish embryo. Cold Spring Harbor Symposia On Quantitative Biology. 62: 227-34. PMID 9598355 DOI: 10.1101/Sqb.1997.062.01.028  0.367
1997 Danielian PS, Echelard Y, Vassileva G, McMahon AP. A 5.5-kb enhancer is both necessary and sufficient for regulation of Wnt-1 transcription in vivo. Developmental Biology. 192: 300-9. PMID 9441669 DOI: 10.1006/Dbio.1997.8762  0.474
1997 Pepicelli CV, Kispert A, Rowitch DH, McMahon AP. GDNF induces branching and increased cell proliferation in the ureter of the mouse. Developmental Biology. 192: 193-8. PMID 9405108 DOI: 10.1006/Dbio.1997.8745  0.645
1997 Ikeya M, Lee SM, Johnson JE, McMahon AP, Takada S. Wnt signalling required for expansion of neural crest and CNS progenitors. Nature. 389: 966-70. PMID 9353119 DOI: 10.1038/40146  0.466
1997 German DC, Ng MC, Liang CL, McMahon A, Iacopino AM. Calbindin-D28k in nerve cell nuclei. Neuroscience. 81: 735-43. PMID 9316025 DOI: 10.1016/S0306-4522(97)00206-6  0.31
1997 Becker S, Wang ZJ, Massey H, Arauz A, Labosky P, Hammerschmidt M, St-Jacques B, Bumcrot D, McMahon A, Grabel L. A role for Indian hedgehog in extraembryonic endoderm differentiation in F9 cells and the early mouse embryo. Developmental Biology. 187: 298-310. PMID 9242425 DOI: 10.1006/Dbio.1997.8616  0.662
1997 Schulte-Merker S, Lee KJ, McMahon AP, Hammerschmidt M. The zebrafish organizer requires chordino. Nature. 387: 862-3. PMID 9202118 DOI: 10.1038/43092  0.55
1997 Serbedzija GN, McMahon AP. Analysis of neural crest cell migration in Splotch mice using a neural crest-specific LacZ reporter. Developmental Biology. 185: 139-47. PMID 9187079 DOI: 10.1006/Dbio.1997.8551  0.411
1997 Yoshikawa Y, Fujimori T, McMahon AP, Takada S. Evidence that absence of Wnt-3a signaling promotes neuralization instead of paraxial mesoderm development in the mouse. Developmental Biology. 183: 234-42. PMID 9126297 DOI: 10.1006/Dbio.1997.8502  0.435
1997 Lee SM, Danielian PS, Fritzsch B, McMahon AP. Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain. Development (Cambridge, England). 124: 959-69. PMID 9056772  0.379
1997 Hammerschmidt M, Brook A, McMahon AP. The world according to hedgehog. Trends in Genetics : Tig. 13: 14-21. PMID 9009843 DOI: 10.1016/S0168-9525(96)10051-2  0.627
1996 Kispert A, Vainio S, Shen L, Rowitch DH, McMahon AP. Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips. Development (Cambridge, England). 122: 3627-37. PMID 8951078  0.625
1996 McMahon AP, Chuang PT. Hedgehogs in the clinic. Nature Medicine. 2: 1308-10. PMID 8946825 DOI: 10.1038/Nm1296-1308  0.382
1996 Serbedzija GN, Dickinson M, McMahon AP. Cell death in the CNS of the Wnt-1 mutant mouse. Journal of Neurobiology. 31: 275-82. PMID 8910786 DOI: 10.1002/(Sici)1097-4695(199611)31:3<275::Aid-Neu1>3.0.Co;2-7  0.385
1996 Mastick GS, Fan CM, Tessier-Lavigne M, Serbedzija GN, McMahon AP, Easter SS. Early deletion of neuromeres in Wnt-1-/- mutant mice: evaluation by morphological and molecular markers. The Journal of Comparative Neurology. 374: 246-58. PMID 8906497 DOI: 10.1002/(Sici)1096-9861(19961014)374:2<246::Aid-Cne7>3.0.Co;2-2  0.353
1996 Danielian PS, McMahon AP. Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development. Nature. 383: 332-4. PMID 8848044 DOI: 10.1038/383332A0  0.516
1996 Hammerschmidt M, Serbedzija GN, McMahon AP. Genetic analysis of dorsoventral pattern formation in the zebrafish: requirement of a BMP-like ventralizing activity and its dorsal repressor. Genes & Development. 10: 2452-61. PMID 8843197 DOI: 10.1101/Gad.10.19.2452  0.665
1996 Bumcrot DA, McMahon AP. Sonic hedgehog: making the gradient. Chemistry & Biology. 3: 13-6. PMID 8807822 DOI: 10.1016/S1074-5521(96)90077-0  0.359
1996 Bitgood MJ, Shen L, McMahon AP. Sertoli cell signaling by Desert hedgehog regulates the male germline. Current Biology : Cb. 6: 298-304. PMID 8805249 DOI: 10.1016/S0960-9822(02)00480-3  0.503
1996 St-Jacques B, McMahon AP. Early mouse development: lessons from gene targeting. Current Opinion in Genetics & Development. 6: 439-44. PMID 8791525 DOI: 10.1016/S0959-437X(96)80065-7  0.352
1996 Epstein DJ, Marti E, Scott MP, McMahon AP. Antagonizing cAMP-dependent protein kinase A in the dorsal CNS activates a conserved Sonic hedgehog signaling pathway. Development (Cambridge, England). 122: 2885-94. PMID 8787761  0.389
1996 Zhang J, Hagopian-Donaldson S, Serbedzija G, Elsemore J, Plehn-Dujowich D, McMahon AP, Flavell RA, Williams T. Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2. Nature. 381: 238-41. PMID 8622766 DOI: 10.1038/381238A0  0.363
1996 Hammerschmidt M, Bitgood MJ, McMahon AP. Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo. Genes & Development. 10: 647-58. PMID 8598293 DOI: 10.1101/Gad.10.6.647  0.673
1995 Iler N, Rowitch DH, Echelard Y, McMahon AP, Abate-Shen C. A single homeodomain binding site restricts spatial expression of Wnt-1 in the developing brain. Mechanisms of Development. 53: 87-96. PMID 8555114 DOI: 10.1016/0925-4773(95)00427-0  0.6
1995 Bumcrot DA, Takada R, McMahon AP. Proteolytic processing yields two secreted forms of sonic hedgehog. Molecular and Cellular Biology. 15: 2294-303. PMID 7891723  0.301
1995 Parr BA, McMahon AP. Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature. 374: 350-3. PMID 7885472 DOI: 10.1038/374350A0  0.477
1995 Martí E, Bumcrot DA, Takada R, McMahon AP. Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants. Nature. 375: 322-5. PMID 7753196 DOI: 10.1038/375322A0  0.354
1995 Dickinson ME, Selleck MA, McMahon AP, Bronner-Fraser M. Dorsalization of the neural tube by the non-neural ectoderm. Development (Cambridge, England). 121: 2099-106. PMID 7635055  0.324
1995 Marigo V, Roberts DJ, Lee SMK, Tsukurov O, Levi T, Gastier JM, Epstein DJ, Gilbert DJ, Copeland NG, Seidman CE, Jenkins NA, Seidman JG, Mcmahon AP, Tabin C. Cloning, Expression, and Chromosomal Location of SHH and IHH: Two Human Homologues of the Drosophila Segment Polarity Gene Hedgehog Genomics. 28: 44-51. PMID 7590746 DOI: 10.1006/Geno.1995.1104  0.335
1995 Bitgood MJ, McMahon AP. Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Developmental Biology. 172: 126-38. PMID 7589793 DOI: 10.1006/Dbio.1995.0010  0.516
1995 Wang MZ, Jin P, Bumcrot DA, Marigo V, McMahon AP, Wang EA, Woolf T, Pang K. Induction of dopaminergic neuron phenotype in the midbrain by Sonic hedgehog protein. Nature Medicine. 1: 1184-8. PMID 7584992 DOI: 10.1038/Nm1195-1184  0.372
1995 Hollyday M, McMahon JA, McMahon AP. Wnt expression patterns in chick embryo nervous system. Mechanisms of Development. 52: 9-25. PMID 7577679 DOI: 10.1016/0925-4773(95)00385-E  0.439
1995 Rowitch DH, McMahon AP. Pax-2 expression in the murine neural plate precedes and encompasses the expression domains of Wnt-1 and En-1. Mechanisms of Development. 52: 3-8. PMID 7577673 DOI: 10.1016/0925-4773(95)00380-J  0.613
1995 Fritzsch B, Nichols DH, Echelard Y, McMahon AP. Development of midbrain and anterior hindbrain ocular motoneurons in normal and Wnt-1 knockout mice. Journal of Neurobiology. 27: 457-69. PMID 7561827 DOI: 10.1002/Neu.480270403  0.387
1995 Burrus LW, McMahon AP. Biochemical analysis of murine Wnt proteins reveals both shared and distinct properties. Experimental Cell Research. 220: 363-73. PMID 7556445 DOI: 10.1006/Excr.1995.1327  0.372
1995 Bumcrot DA, McMahon AP. Somite differentiation. Sonic signals somites. Current Biology : Cb. 5: 612-4. PMID 7552169 DOI: 10.1016/S0960-9822(95)00123-0  0.437
1995 Münsterberg AE, Kitajewski J, Bumcrot DA, McMahon AP, Lassar AB. Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite. Genes & Development. 9: 2911-22. PMID 7498788 DOI: 10.1101/Gad.9.23.2911  0.449
1995 Lee SMK, Dickinson ME, Parr BA, Vainio S, McMahon AP. Molecular genetic analysis of Wnt signals in mouse development Seminars in Developmental Biology. 6: 267-274. DOI: 10.1016/S1044-5781(06)80052-6  0.481
1994 Takada S, Stark KL, Shea MJ, Vassileva G, McMahon JA, McMahon AP. Wnt-3a regulates somite and tailbud formation in the mouse embryo. Genes & Development. 8: 174-89. PMID 8299937 DOI: 10.1101/Gad.8.2.174  0.417
1994 Zimmerman L, Parr B, Lendahl U, Cunningham M, McKay R, Gavin B, Mann J, Vassileva G, McMahon A. Independent regulatory elements in the nestin gene direct transgene expression to neural stem cells or muscle precursors. Neuron. 12: 11-24. PMID 8292356 DOI: 10.1016/0896-6273(94)90148-1  0.418
1994 Dickinson ME, Krumlauf R, McMahon AP. Evidence for a mitogenic effect of Wnt-1 in the developing mammalian central nervous system. Development (Cambridge, England). 120: 1453-71. PMID 8050356  0.365
1994 Stark K, Vainio S, Vassileva G, McMahon AP. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature. 372: 679-83. PMID 7990960 DOI: 10.1038/372679A0  0.466
1994 Parr BA, McMahon AP. Wnt genes and vertebrate development. Current Opinion in Genetics & Development. 4: 523-8. PMID 7950319 DOI: 10.1016/0959-437X(94)90067-D  0.427
1994 Echelard Y, Vassileva G, McMahon AP. Cis-acting regulatory sequences governing Wnt-1 expression in the developing mouse CNS. Development (Cambridge, England). 120: 2213-24. PMID 7925022  0.388
1994 McMahon AP. Mouse development. Winged-helix in axial patterning. Current Biology : Cb. 4: 903-6. PMID 7850424 DOI: 10.1016/S0960-9822(00)00200-1  0.33
1993 McMahon AP. Cell signalling in induction and anterior-posterior patterning of the vertebrate central nervous system. Current Opinion in Neurobiology. 3: 4-7. PMID 8453288 DOI: 10.1016/0959-4388(93)90027-V  0.436
1993 Echelard Y, Epstein DJ, St-Jacques B, Shen L, Mohler J, McMahon JA, McMahon AP. Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell. 75: 1417-30. PMID 7916661 DOI: 10.1016/0092-8674(93)90627-3  0.44
1992 McMahon AP, Joyner AL, Bradley A, McMahon JA. The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum. Cell. 69: 581-95. PMID 1534034 DOI: 10.1016/0092-8674(92)90222-X  0.458
1992 McMahon AP, Gavin BJ, Parr B, Bradley A, McMahon JA. The Wnt family of cell signalling molecules in postimplantation development of the mouse. Ciba Foundation Symposium. 165: 199-212; discussion . PMID 1516469  0.363
1992 Del Amo FF, Smith DE, Swiatek PJ, Gendron-Maguire M, Greenspan RJ, McMahon AP, Gridley T. Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. Development (Cambridge, England). 115: 737-44. PMID 1425352  0.385
1992 Dickinson ME, McMahon AP. The role of Wnt genes in vertebrate development. Current Opinion in Genetics & Development. 2: 562-6. PMID 1388080 DOI: 10.1016/S0959-437X(05)80172-8  0.44
1992 Gavin BJ, McMahon AP. Differential regulation of the Wnt gene family during pregnancy and lactation suggests a role in postnatal development of the mammary gland. Molecular and Cellular Biology. 12: 2418-23. PMID 1373817  0.353
1992 McMahon AP. The Wnt family of developmental regulators Trends in Genetics. 8: 236-242. DOI: 10.1016/0168-9525(92)90393-I  0.378
1991 Christian JL, Gavin BJ, McMahon AP, Moon RT. Isolation of cDNAs partially encoding four Xenopus Wnt-1/int-1-related proteins and characterization of their transient expression during embryonic development. Developmental Biology. 143: 230-4. PMID 1991549 DOI: 10.1016/0012-1606(91)90073-C  0.386
1991 Christian JL, McMahon JA, McMahon AP, Moon RT. Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderm-inducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis. Development (Cambridge, England). 111: 1045-55. PMID 1879349  0.357
1990 Gavin BJ, McMahon JA, McMahon AP. Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. Genes & Development. 4: 2319-32. PMID 2279700 DOI: 10.1101/Gad.4.12B.2319  0.426
1990 McMahon AP, Bradley A. The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell. 62: 1073-85. PMID 2205396 DOI: 10.1016/0092-8674(90)90385-R  0.447
1989 Wilkinson DG, Bhatt S, McMahon AP. Expression pattern of the FGF-related proto-oncogene int-2 suggests multiple roles in fetal development. Development (Cambridge, England). 105: 131-6. PMID 2680421  0.329
1989 McMahon AP, Moon RT. Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis. Cell. 58: 1075-84. PMID 2673541 DOI: 10.1016/0092-8674(89)90506-0  0.429
1989 McMahon AP, Moon RT. int-1--a proto-oncogene involved in cell signalling. Development (Cambridge, England). 107: 161-7. PMID 2534596  0.349
1988 Wilkinson DG, Peters G, Dickson C, McMahon AP. Expression of the FGF-related proto-oncogene int-2 during gastrulation and neurulation in the mouse. The Embo Journal. 7: 691-5. PMID 3293998  0.334
1985 Flytzanis CN, McMahon AP, Hough-Evans BR, Katula KS, Britten RJ, Davidson EH. Persistence and integration of cloned DNA in postembryonic sea urchins. Developmental Biology. 108: 431-42. PMID 3000855 DOI: 10.1016/0012-1606(85)90046-6  0.354
1985 McMahon AP, Flytzanis CN, Hough-Evans BR, Katula KS, Britten RJ, Davidson EH. Introduction of cloned DNA into sea urchin egg cytoplasm: replication and persistence during embryogenesis. Developmental Biology. 108: 420-30. PMID 3000854 DOI: 10.1016/0012-1606(85)90045-4  0.385
1984 McMahon AP, Novak TJ, Britten RJ, Davidson EH. Inducible expression of a cloned heat shock fusion gene in sea urchin embryos. Proceedings of the National Academy of Sciences of the United States of America. 81: 7490-4. PMID 6594699 DOI: 10.1073/Pnas.81.23.7490  0.508
1983 McMahon A, Monk M. X-chromosome activity in female mouse embryos heterozygous for Pgk-1 and Searle's translocation, T(X; 16) 16H. Genetical Research. 41: 69-83. PMID 6840549 DOI: 10.1017/S0016672300021078  0.624
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