William Harvey Fleming - Publications

Affiliations: 
Medical Genetics Oregon Health and Science University, Portland, OR 

70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Rodríguez A, Zhang K, Färkkilä A, Filiatrault J, Yang C, Velázquez M, Furutani E, Goldman DC, García de Teresa B, Garza-Mayén G, McQueen K, Sambel LA, Molina B, Torres L, González M, ... ... Fleming WH, et al. MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia. Cell Stem Cell. PMID 32997960 DOI: 10.1016/j.stem.2020.09.004  0.332
2020 Wortham AM, Goldman DC, Chen J, Fleming WH, Zhang AS, Enns CA. Extrahepatic deficiency of transferrin receptor 2 is associated with increased erythropoiesis independent of iron overload. The Journal of Biological Chemistry. PMID 32054685 DOI: 10.1074/Jbc.Ra119.010535  0.317
2018 Klug LR, Bannon AE, Javidi-Sharifi N, Town A, Fleming WH, VanSlyke JK, Musil LS, Fletcher JA, Tyner JW, Heinrich MC. LMTK3 is essential for oncogenic KIT expression in KIT-mutant GIST and melanoma. Oncogene. PMID 30242244 DOI: 10.1038/S41388-018-0508-5  0.338
2017 Janghorban M, Langer EM, Wang X, Zachman D, Daniel CJ, Hooper J, Fleming WH, Agarwal A, Sears RC. The tumor suppressor phosphatase PP2A-B56α regulates stemness and promotes the initiation of malignancies in a novel murine model. Plos One. 12: e0188910. PMID 29190822 DOI: 10.1371/Journal.Pone.0188910  0.421
2016 Zachman D, Goldman DC, Guha C, Wilmot B, Fleming WH. Transforming Growth Factor- β1 Signaling in Vascular Endothelial Cells Inhibits Hematopoietic Stem Cell Regeneration Blood. 128: 1493-1493. DOI: 10.1182/Blood.V128.22.1493.1493  0.348
2015 Yao H, Goldman DC, Fan G, Mandel G, Fleming WH. The co-repressor Rcor1 is essential for normal myeloerythroid lineage differentiation. Stem Cells (Dayton, Ohio). PMID 26119982 DOI: 10.1002/Stem.2086  0.515
2015 Goldman DC, Alexeev V, Lash E, Guha C, Rodeck U, Fleming WH. The triterpenoid RTA 408 is a robust mitigator of hematopoietic acute radiation syndrome in mice. Radiation Research. 183: 338-44. PMID 25738896 DOI: 10.1667/Rr13900.1  0.363
2015 Janghorban M, Zachman D, Wang X, Agarwal A, Fleming W, Sears R. Abstract 3180: Regulation of stem cells by the tumor suppressor PP2A-B56α Cancer Research. 75: 3180-3180. DOI: 10.1158/1538-7445.Am2015-3180  0.486
2014 Yao H, Goldman DC, Nechiporuk T, Kawane S, McWeeney SK, Tyner JW, Fan G, Kerenyi MA, Orkin SH, Fleming WH, Mandel G. Corepressor Rcor1 is essential for murine erythropoiesis. Blood. 123: 3175-84. PMID 24652990 DOI: 10.1182/Blood-2013-11-538678  0.444
2014 Cogle CR, Goldman DC, Madlambayan GJ, Leon RP, Al Masri A, Clark HA, Asbaghi SA, Tyner JW, Dunlap J, Fan G, Kovacsovics T, Liu Q, Meacham A, Hamlin KL, Hromas RA, ... ... Fleming WH, et al. Functional integration of acute myeloid leukemia into the vascular niche. Leukemia. 28: 1978-87. PMID 24637335 DOI: 10.1038/Leu.2014.109  0.437
2014 Hakki M, Goldman DC, Streblow DN, Hamlin KL, Krekylwich CN, Fleming WH, Nelson JA. HCMV infection of humanized mice after transplantation of G-CSF-mobilized peripheral blood stem cells from HCMV-seropositive donors. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 20: 132-5. PMID 24161922 DOI: 10.1016/J.Bbmt.2013.10.019  0.435
2014 Zachman DK, Goldman DC, Hamlin KL, Guha C, Fleming WH. Role of Hepatocyte Growth Factor in Endothelial-Dependent Hematopoietic Stem Cell Regeneration Blood. 124: 4369-4369. DOI: 10.1182/Blood.V124.21.4369.4369  0.487
2014 Goldman DC, Yao H, Fan G, Mandel G, Fleming WH. Rcor1 Deficiency Disrupts Myeloerythroid Lineage Differentiation and Causes Severe Myelodysplasia Blood. 124: 3248-3248. DOI: 10.1182/Blood.V124.21.3248.3248  0.472
2013 Zachman DK, Leon RP, Das P, Goldman DC, Hamlin KL, Guha C, Fleming WH. Endothelial cells mitigate DNA damage and promote the regeneration of hematopoietic stem cells after radiation injury. Stem Cell Research. 11: 1013-21. PMID 23939266 DOI: 10.1016/J.Scr.2013.07.001  0.5
2013 Zachman D, Leon RP, Das P, Goldman DC, Hamlin KL, Guha C, Fleming WH. Endothelial Cells Mitigate DNA Damage and Restore Function in Irradiated Hematopoietic Stem Cells International Journal of Radiation Oncology Biology Physics. 87. DOI: 10.1016/J.Ijrobp.2013.06.059  0.329
2011 Umashankar M, Petrucelli A, Cicchini L, Caposio P, Kreklywich CN, Rak M, Bughio F, Goldman DC, Hamlin KL, Nelson JA, Fleming WH, Streblow DN, Goodrum F. A novel human cytomegalovirus locus modulates cell type-specific outcomes of infection. Plos Pathogens. 7: e1002444. PMID 22241980 DOI: 10.1371/Journal.Ppat.1002444  0.332
2011 Cogle CR, Madlambayan GJ, Goldman DC, Al Masri A, Leon RP, Dunlap J, Kovacsovics T, Liu Q, Meacham A, Scott EW, Fleming WH. Acute Myeloid Leukemia Cells Generate Leukemic Endothelial Cells with Leukemogenic Potential: Blood Vessels As Sanctuaries for Leukemia Relapse Blood. 118: 241-241. DOI: 10.1182/Blood.V118.21.241.241  0.503
2010 Smith MS, Goldman DC, Bailey AS, Pfaffle DL, Kreklywich CN, Spencer DB, Othieno FA, Streblow DN, Garcia JV, Fleming WH, Nelson JA. Granulocyte-colony stimulating factor reactivates human cytomegalovirus in a latently infected humanized mouse model. Cell Host & Microbe. 8: 284-91. PMID 20833379 DOI: 10.1016/J.Chom.2010.08.001  0.395
2010 Zhang QS, Marquez-Loza L, Eaton L, Duncan AW, Goldman DC, Anur P, Watanabe-Smith K, Rathbun RK, Fleming WH, Bagby GC, Grompe M. Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol. Blood. 116: 5140-8. PMID 20826722 DOI: 10.1182/Blood-2010-04-278226  0.46
2010 Li B, Bailey AS, Jiang S, Liu B, Goldman DC, Fleming WH. Endothelial cells mediate the regeneration of hematopoietic stem cells. Stem Cell Research. 4: 17-24. PMID 19720572 DOI: 10.1016/J.Scr.2009.08.001  0.543
2010 Masri AA, Goldman DC, Asbaghi SA, Clark HA, Leon RP, Liu Q, Hickey RD, Grompe M, Kurre P, Fleming WH. Acute Myeloid Leukemia Cells Fuse with Vascular Endothelium Blood. 116: 504-504. DOI: 10.1182/Blood.V116.21.504.504  0.5
2010 Shurtleff MJ, Skinner AM, Hornick N, Fleming WH, Roberts CT, Kurre P. AML-Derived Microvesicles as Mediators of Cell-Cell Signaling In the Leukemic Microenvironment Blood. 116: 1700-1700. DOI: 10.1182/Blood.V116.21.1700.1700  0.426
2009 Goldman DC, Bailey AS, Pfaffle DL, Al Masri A, Christian JL, Fleming WH. BMP4 regulates the hematopoietic stem cell niche. Blood. 114: 4393-401. PMID 19759357 DOI: 10.1182/Blood-2009-02-206433  0.513
2009 Kampa KM, Acoba JD, Chen D, Gay J, Lee H, Beemer K, Padiernos E, Boonmark N, Zhu Z, Fan AC, Bailey AS, Fleming WH, Corless C, Felsher DW, Naumovski L, et al. Apoptosis-stimulating protein of p53 (ASPP2) heterozygous mice are tumor-prone and have attenuated cellular damage-response thresholds. Proceedings of the National Academy of Sciences of the United States of America. 106: 4390-5. PMID 19251665 DOI: 10.1073/Pnas.0809080106  0.323
2009 Tibbitts DC, Fleming W, Fan G, Sears R. Abstract A28: Aberrant c‐Myc protein stabilization and Axin1 deregulation in acute leukemia Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-A28  0.344
2008 Jiang S, Bailey AS, Goldman DC, Swain JR, Wong MH, Streeter PR, Fleming WH. Hematopoietic stem cells contribute to lymphatic endothelium. Plos One. 3: e3812. PMID 19043576 DOI: 10.1182/Blood.V108.11.1658.1658  0.493
2008 Liu H, Huang J, Wang J, Jiang S, Bailey AS, Goldman DC, Welcker M, Bedell V, Slovak ML, Clurman B, Thayer M, Fleming WH, Epner E. Transvection mediated by the translocated cyclin D1 locus in mantle cell lymphoma. The Journal of Experimental Medicine. 205: 1843-58. PMID 18625744 DOI: 10.1084/Jem.20072102  0.368
2008 Pfaffle DL, Jiang S, Goldman DC, Fleming WH. Hematopoietic Stem Cells Mediate the Repair of Damaged Endothelium Blood. 112: 5458-5458. DOI: 10.1182/Blood.V112.11.5458.5458  0.488
2008 Goldman DC, Bailey AS, Pfaffle DL, Christian JL, Fleming WH. Bone Morphogenetic Protein 4 Regulates Hematopoietic Stem Cell Maintenance in Vivo. Blood. 112: 1399-1399. DOI: 10.1182/Blood.V112.11.1399.1399  0.514
2008 Meyers G, Dunn A, Kovacsovics T, Fleming W, Epner E, Hayes-Lattin B, Mauro M, Deininger M, Bubalo J, Maziarz R. 318: Busulfan, Fludarabine and Total Body Irradiation Followed by Allogeneic Peripheral Blood Stem Cell Transplantation is an Effective Treatment for Hematologic Malignancies with Acceptable Toxicity in a Higher-Risk Population Biology of Blood and Marrow Transplantation. 14: 117. DOI: 10.1016/J.Bbmt.2007.12.328  0.43
2007 Epner EM, Huang J, Liu H, Wang J, Liang S, Fleming WH. CTCF and Nucleophosmin Participate in Long Distance Cyclin D1 Deregulation in Mantle Cell Lymphoma. Blood. 110: 989-989. DOI: 10.1182/Blood.V110.11.989.989  0.346
2007 Kovacsovics T, Hayes-Lattin B, Riegert K, Subbiah N, Curtin PT, Leis JF, Mauro MM, Epner EE, Fleming WH, Meyers GM, Deininger MW, Dunn A, Maziarz RT. 257: Validation of the hematopoietic cell transplantation-comorbidity index (HCT-CI) for non-relapse mortality (NRM) and survival after matched unrelated donor SCT Biology of Blood and Marrow Transplantation. 13: 94. DOI: 10.1016/J.Bbmt.2006.12.262  0.38
2006 Bailey AS, Willenbring H, Jiang S, Anderson DA, Schroeder DA, Wong MH, Grompe M, Fleming WH. Myeloid lineage progenitors give rise to vascular endothelium. Proceedings of the National Academy of Sciences of the United States of America. 103: 13156-61. PMID 16920790 DOI: 10.1073/Pnas.0604203103  0.473
2006 Spangrude GJ, Cho S, Guedelhoefer O, Vanwoerkom RC, Fleming WH. Mouse models of hematopoietic engraftment: limitations of transgenic green fluorescent protein strains and a high-performance liquid chromatography approach to analysis of erythroid chimerism. Stem Cells (Dayton, Ohio). 24: 2045-51. PMID 16690777 DOI: 10.1634/Stemcells.2006-0013  0.643
2006 Rizvi AZ, Swain JR, Davies PS, Bailey AS, Decker AD, Willenbring H, Grompe M, Fleming WH, Wong MH. Bone marrow-derived cells fuse with normal and transformed intestinal stem cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 6321-5. PMID 16606845 DOI: 10.1073/Pnas.0508593103  0.51
2006 Held PK, Al-Dhalimy M, Willenbring H, Akkari Y, Jiang S, Torimaru Y, Olson S, Fleming WH, Finegold M, Grompe M. In vivo genetic selection of renal proximal tubules. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 49-58. PMID 16216560 DOI: 10.1016/J.Ymthe.2005.09.004  0.459
2006 Epner E, Huang J, Liu H, Wang J, Fleming W. Transvection Mediated by the Translocated Cyclin D1 Locus in B Cell Malignancies. Blood. 108: 357-357. DOI: 10.1182/Blood.V108.11.357.357  0.309
2006 Epner E, Jing H, Jin W, Fleming WH. Mantle Cell Lymphoma: An Epigenetic Disease of Cyclin D1 Deregulation Involving Nucleophosmin, CTCF and Small RNA’s. Blood. 108: 2236-2236. DOI: 10.1182/Blood.V108.11.2236.2236  0.36
2006 Fleming WH, Bailey AS, Jiang S, Li B. 2604 : Radioprotection of Hematopoietic Stem Cells by Vascular Endothelium International Journal of Radiation Oncology Biology Physics. 66. DOI: 10.1016/J.Ijrobp.2006.07.1018  0.456
2006 Hayes-Lattin B, Leis JF, Curtin PT, Dunn A, Epner E, Fleming WH, Kovacsovics T, Mauro MJ, Moore M, Simic A, Subbiah N, Maziarz RT. Outcomes associated with a steroid-containing acute GVHD prophylaxis regimen for matched unrelated donor (MUD) hematopoietic stem cell transplantation Biology of Blood and Marrow Transplantation. 12: 68. DOI: 10.1016/J.Bbmt.2005.11.213  0.442
2005 Anderson DA, Wu Y, Jiang S, Zhang X, Streeter PR, Spangrude GJ, Archer DR, Fleming WH. Donor marker infidelity in transgenic hematopoietic stem cells. Stem Cells (Dayton, Ohio). 23: 638-43. PMID 15849171 DOI: 10.1634/Stemcells.2004-0325  0.694
2005 Carlson H, Zhang AS, Fleming WH, Enns CA. The hereditary hemochromatosis protein, HFE, lowers intracellular iron levels independently of transferrin receptor 1 in TRVb cells. Blood. 105: 2564-70. PMID 15528318 DOI: 10.1182/Blood-2004-03-1204  0.331
2005 Bailey AS, Willenbring H, Jiang S, Schroeder DA, Anderson DA, Grompe M, Wong MH, Fleming WH. Myeloid Lineage-Restricted Progenitors Contribute to Vascular Endothelium. Blood. 106: 2267-2267. DOI: 10.1182/Blood.V106.11.2267.2267  0.509
2005 Fleming WH. Endothelial cell–specific markers: going... going... gone Blood. 106: 769-769. DOI: 10.1182/Blood-2005-05-1893  0.439
2005 Hayes-Lattin B, Mehta P, Dunn A, Subbiah N, Leis JF, Simic A, Allen B, Balleisen S, Curtin PT, Epner E, Fleming WH, Jacoby C, Mauro MJ, Nichols CR, Schubach S, et al. Survival after autologous transplantation to treat diffuse large B-cell lymphoma with a history of central nervous system involvement, bone marrow involvement, or histological transformation Biology of Blood and Marrow Transplantation. 11: 77. DOI: 10.1016/J.Bbmt.2004.12.229  0.386
2004 Jiang S, Walker L, Afentoulis M, Anderson DA, Jauron-Mills L, Corless CL, Fleming WH. Transplanted human bone marrow contributes to vascular endothelium. Proceedings of the National Academy of Sciences of the United States of America. 101: 16891-6. PMID 15548607 DOI: 10.1182/Blood.V104.11.2687.2687  0.502
2004 Willenbring H, Bailey AS, Foster M, Akkari Y, Dorrell C, Olson S, Finegold M, Fleming WH, Grompe M. Myelomonocytic cells are sufficient for therapeutic cell fusion in liver. Nature Medicine. 10: 744-8. PMID 15195088 DOI: 10.1038/Nm1062  0.493
2004 Baumann CI, Bailey AS, Li W, Ferkowicz MJ, Yoder MC, Fleming WH. PECAM-1 is expressed on hematopoietic stem cells throughout ontogeny and identifies a population of erythroid progenitors. Blood. 104: 1010-6. PMID 15126319 DOI: 10.1182/Blood-2004-03-0989  0.467
2004 Bailey AS, Jiang S, Afentoulis M, Baumann CI, Schroeder DA, Olson SB, Wong MH, Fleming WH. Transplanted adult hematopoietic stems cells differentiate into functional endothelial cells. Blood. 103: 13-9. PMID 12958072 DOI: 10.1182/Blood-2003-05-1684  0.541
2004 Hayes-Lattin B, Mehta P, Dunn A, Subbiah N, Leis JF, Simic A, Allen B, Balliesen S, Curtin PT, Epner E, Fleming WH, Jacoby C, Mauro MJ, Nichols CR, Schubach S, et al. Survival after Autologous Transplantation to Treat Diffuse Large B-Cell Lymphoma with a History of CNS Involvement, Bone Marrow Involvement, or Histologic Transformation. Blood. 104: 5237-5237. DOI: 10.1182/Blood.V104.11.5237.5237  0.395
2003 Streeter PR, Dudley LZ, Fleming WH. Activation of the G-CSF and Flt-3 receptors protects hematopoietic stem cells from lethal irradiation. Experimental Hematology. 31: 1119-25. PMID 14585378 DOI: 10.1016/S0301-472X(03)00257-1  0.504
2003 Bailey AS, Fleming WH. Converging roads: evidence for an adult hemangioblast. Experimental Hematology. 31: 987-93. PMID 14585360 DOI: 10.1016/J.Exphem.2003.07.001  0.487
2003 Fleming WH. Multitalented embryonic endothelial cells: a new role in stem cell expansion Blood. 102: 4248-4249. DOI: 10.1182/Blood-2003-09-3326  0.486
2003 Fleming WH, Jiang S, Afentoulis M, Baumann CI, Wong MH, Bailey AS. 221Reconstitution of vascular endothelium following transplantation of bone marrow derived stem cells Biology of Blood and Marrow Transplantation. 9: 128. DOI: 10.1016/S1083-8791(03)80210-0  0.476
2002 Hayes-Lattin BM, Curtin PT, Fleming WH, Leis JF, Stepan DE, Schubach S, Maziarz RT. Toxic megacolon: a life-threatening complication of high-dose therapy and autologous stem cell transplantation among patients with AL amyloidosis. Bone Marrow Transplantation. 30: 279-85. PMID 12209349 DOI: 10.1038/Sj.Bmt.1703627  0.412
2002 Montfort MJ, Olivares CR, Mulcahy JM, Fleming WH. Adult blood vessels restore host hematopoiesis following lethal irradiation. Experimental Hematology. 30: 950-6. PMID 12160847 DOI: 10.1016/S0301-472X(02)00813-5  0.502
2001 Fleming WH, Mulcahy JM, McKearn JP, Streeter PR. Progenipoietin-1: a multifunctional agonist of the granulocyte colony-stimulating factor receptor and fetal liver tyrosine kinase-3 is a potent mobilizer of hematopoietic stem cells. Experimental Hematology. 29: 943-51. PMID 11495700 DOI: 10.1016/S0301-472X(01)00675-0  0.482
2000 Fleming WH. Hematopoietic potential of adult vascular tissue Experimental Hematology. 28: 128. DOI: 10.1016/S0301-472X(00)00496-3  0.475
1999 Fleming WH, Lankford-Turner P, Turner CW, Wong J, Strobert E, McKearn JP. Administration of daniplestim and granulocyte colony-stimulating factor for the mobilization of hematopoietic progenitor cells in nonhuman primates. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 5: 8-14. PMID 10232736 DOI: 10.1053/Bbmt.1999.V5.Pm10232736  0.318
1999 Battaile KP, Bateman RL, Mortimer D, Mulcahy J, Rathbun RK, Bagby G, Fleming WH, Grompe M. In Vivo Selection of Wild-Type Hematopoietic Stem Cells in a Murine Model of Fanconi Anemia Blood. 94: 2151-2158. DOI: 10.1182/Blood.V94.6.2151  0.473
1998 Turner CW, Archer DR, Wong J, Yeager AM, Fleming WH. In utero transplantation of human fetal haemopoietic cells in NOD/SCID mice. British Journal of Haematology. 103: 326-34. PMID 9827901 DOI: 10.1046/J.1365-2141.1998.01003.X  0.496
1998 Bomberger C, Singh-Jairam M, Rodey G, Guerriero A, Yeager AM, Fleming WH, Holland HK, Waller EK. Lymphoid reconstitution after autologous PBSC transplantation with FACS-sorted CD34+ hematopoietic progenitors. Blood. 91: 2588-600. PMID 9516161  0.33
1998 Bomberger C, Singh-Jairam M, Rodey G, Guerriero A, Yeager AM, Fleming WH, Holland HK, Waller EK. Lymphoid Reconstitution After Autologous PBSC Transplantation With FACS-Sorted CD34+ Hematopoietic Progenitors Blood. 91: 2588-2600. DOI: 10.1182/Blood.V91.7.2588.2588_2588_2600  0.434
1997 Archer DR, Turner CW, Yeager AM, Fleming WH. Sustained Multilineage Engraftment of Allogeneic Hematopoietic Stem Cells in NOD/SCID Mice After In Utero Transplantation Blood. 90: 3222-3229. DOI: 10.1182/Blood.V90.8.3222  0.522
1996 Turner CW, Yeager AM, Waller EK, Wingard JR, Fleming WH. Engraftment potential of different sources of human hematopoietic progenitor cells in BNX Mice. Blood. 87: 3237-44. PMID 8605339 DOI: 10.1182/Blood.V87.8.3237.Bloodjournal8783237  0.44
1995 Neal T, Holland H, Baum C, Villinger F, Ansari A, Saral R, Wingard J, Fleming W. CD34+ progenitor cells from asymptomatic patients are not a major reservoir for human immunodeficiency virus-1 Blood. 86: 1749-1756. DOI: 10.1182/Blood.V86.5.1749.Bloodjournal8651749  0.364
1994 Uchida N, Aguila HL, Fleming WH, Jerabek L, Weissman IL. Rapid and sustained hematopoietic recovery in lethally irradiated mice transplanted with purified Thy-1.1lo Lin-Sca-1+ hematopoietic stem cells. Blood. 83: 3758-79. PMID 7911343 DOI: 10.1182/Blood.V83.12.3758.Bloodjournal83123758  0.531
1993 Fleming WH, Alpern EJ, Uchida N, Ikuta K, Spangrude GJ, Weissman IL. Functional heterogeneity is associated with the cell cycle status of murine hematopoietic stem cells. The Journal of Cell Biology. 122: 897-902. PMID 8349737 DOI: 10.1083/Jcb.122.4.897  0.662
1993 Uchida N, Fleming WH, Alpern EJ, Weissman IL. Heterogeneity of hematopoietic stem cells. Current Opinion in Immunology. 5: 177-84. PMID 8099486 DOI: 10.1016/0952-7915(93)90002-A  0.481
1993 Fleming WH, Alpern EJ, Uchida N, Ikuta K, Weissman IL. Steel factor influences the distribution and activity of murine hematopoietic stem cells in vivo. Proceedings of the National Academy of Sciences of the United States of America. 90: 3760-4. PMID 7682717 DOI: 10.1073/Pnas.90.8.3760  0.511
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