Linda Van Aelst - Publications

Affiliations: 
Neuroscience Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ogawa Y, Lim BC, George S, Oses-Prieto JA, Rasband JM, Eshed-Eisenbach Y, Hamdan H, Nair S, Boato F, Peles E, Burlingame AL, Van Aelst L, Rasband MN. Antibody-directed extracellular proximity biotinylation reveals that Contactin-1 regulates axo-axonic innervation of axon initial segments. Nature Communications. 14: 6797. PMID 37884508 DOI: 10.1038/s41467-023-42273-8  0.727
2021 Ge EJ, Bush AI, Casini A, Cobine PA, Cross JR, DeNicola GM, Dou QP, Franz KJ, Gohil VM, Gupta S, Kaler SG, Lutsenko S, Mittal V, Petris MJ, Polishchuk R, ... ... Van Aelst L, et al. Connecting copper and cancer: from transition metal signalling to metalloplasia. Nature Reviews. Cancer. PMID 34764459 DOI: 10.1038/s41568-021-00417-2  0.557
2021 Wang M, Gallo NB, Tai Y, Li B, Van Aelst L. Oligophrenin-1 moderates behavioral responses to stress by regulating parvalbumin interneuron activity in the medial prefrontal cortex. Neuron. PMID 33831348 DOI: 10.1016/j.neuron.2021.03.016  0.43
2019 Tai Y, Gallo NB, Wang M, Yu JR, Van Aelst L. Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM. Neuron. PMID 30846310 DOI: 10.1016/j.neuron.2019.02.009  0.446
2015 Penzo MA, Robert V, Tucciarone J, De Bundel D, Wang M, Van Aelst L, Darvas M, Parada LF, Palmiter RD, He M, Huang ZJ, Li B. The paraventricular thalamus controls a central amygdala fear circuit. Nature. 519: 455-9. PMID 25600269 DOI: 10.1038/Nature13978  0.454
2014 Nakano-Kobayashi A, Tai Y, Nadif Kasri N, Van Aelst L. The X-linked mental retardation protein OPHN1 interacts with Homer1b/c to control spine endocytic zone positioning and expression of synaptic potentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8665-71. PMID 24966368 DOI: 10.1523/JNEUROSCI.0894-14.2014  0.626
2013 Anne SL, Govek EE, Ayrault O, Kim JH, Zhu X, Murphy DA, Van Aelst L, Roussel MF, Hatten ME. WNT3 inhibits cerebellar granule neuron progenitor proliferation and medulloblastoma formation via MAPK activation. Plos One. 8: e81769. PMID 24303070 DOI: 10.1371/Journal.Pone.0081769  0.703
2011 Nadif Kasri N, Nakano-Kobayashi A, Van Aelst L. Rapid synthesis of the X-linked mental retardation protein OPHN1 mediates mGluR-dependent LTD through interaction with the endocytic machinery. Neuron. 72: 300-15. PMID 22017989 DOI: 10.1016/j.neuron.2011.09.001  0.643
2011 Govek EE, Hatten ME, Van Aelst L. The role of Rho GTPase proteins in CNS neuronal migration. Developmental Neurobiology. 71: 528-53. PMID 21557504 DOI: 10.1002/dneu.20850  0.684
2010 Nadif Kasri N, Van Aelst L. Spines and Mental Disorders Encyclopedia of Neuroscience. 329-335. DOI: 10.1016/B978-008045046-9.01797-6  0.563
2009 Nadif Kasri N, Nakano-Kobayashi A, Malinow R, Li B, Van Aelst L. The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors. Genes & Development. 23: 1289-302. PMID 19487570 DOI: 10.1101/Gad.1783809  0.645
2008 Hu H, Qin Y, Bochorishvili G, Zhu Y, van Aelst L, Zhu JJ. Ras signaling mechanisms underlying impaired GluR1-dependent plasticity associated with fragile X syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7847-62. PMID 18667617 DOI: 10.1523/Jneurosci.1496-08.2008  0.327
2008 Kasri NN, Govek EE, Van Aelst L. Characterization of oligophrenin-1, a RhoGAP lost in patients affected with mental retardation: lentiviral injection in organotypic brain slice cultures. Methods in Enzymology. 439: 255-66. PMID 18374170 DOI: 10.1016/S0076-6879(07)00419-3  0.684
2008 Nadif Kasri N, Van Aelst L. Rho-linked genes and neurological disorders. Pflã¼Gers Archiv : European Journal of Physiology. 455: 787-97. PMID 18004590 DOI: 10.1007/s00424-007-0385-1  0.652
2006 Watabe-Uchida M, Govek EE, Van Aelst L. Regulators of Rho GTPases in neuronal development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10633-5. PMID 17050702 DOI: 10.1523/Jneurosci.4084-06.2006  0.69
2006 Zhao M, Janas JA, Niki M, Pandolfi PP, Van Aelst L. Dok-1 independently attenuates Ras/mitogen-activated protein kinase and Src/c-myc pathways to inhibit platelet-derived growth factor-induced mitogenesis. Molecular and Cellular Biology. 26: 2479-89. PMID 16537894 DOI: 10.1128/Mcb.26.7.2479-2489.2006  0.526
2005 Qin Y, Zhu Y, Baumgart JP, Stornetta RL, Seidenman K, Mack V, van Aelst L, Zhu JJ. State-dependent Ras signaling and AMPA receptor trafficking. Genes & Development. 19: 2000-15. PMID 16107614 DOI: 10.1101/Gad.342205  0.322
2005 Newey SE, Velamoor V, Govek EE, Van Aelst L. Rho GTPases, dendritic structure, and mental retardation. Journal of Neurobiology. 64: 58-74. PMID 15884002 DOI: 10.1002/Neu.20153  0.706
2005 Govek EE, Newey SE, Van Aelst L. The role of the Rho GTPases in neuronal development. Genes & Development. 19: 1-49. PMID 15630019 DOI: 10.1101/Gad.1256405  0.698
2004 Niki M, Di Cristofano A, Zhao M, Honda H, Hirai H, Van Aelst L, Cordon-Cardo C, Pandolfi PP. Role of Dok-1 and Dok-2 in leukemia suppression. The Journal of Experimental Medicine. 200: 1689-95. PMID 15611295 DOI: 10.1084/Jem.20041306  0.472
2004 Govek EE, Newey SE, Akerman CJ, Cross JR, Van der Veken L, Van Aelst L. The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis. Nature Neuroscience. 7: 364-72. PMID 15034583 DOI: 10.1038/Nn1210  0.756
2003 Boettner B, Harjes P, Ishimaru S, Heke M, Fan HQ, Qin Y, Van Aelst L, Gaul U. The AF-6 homolog canoe acts as a Rap1 effector during dorsal closure of the Drosophila embryo. Genetics. 165: 159-69. PMID 14504224  0.308
2002 Zhu JJ, Qin Y, Zhao M, Van Aelst L, Malinow R. Ras and Rap control AMPA receptor trafficking during synaptic plasticity. Cell. 110: 443-55. PMID 12202034 DOI: 10.1016/S0092-8674(02)00897-8  0.47
2002 Van Aelst L, Symons M. Role of Rho family GTPases in epithelial morphogenesis. Genes & Development. 16: 1032-54. PMID 12000787 DOI: 10.1101/Gad.978802  0.343
2002 Boettner B, Van Aelst L. The role of Rho GTPases in disease development. Gene. 286: 155-74. PMID 11943472 DOI: 10.1016/S0378-1119(02)00426-2  0.319
2001 Di Cristofano A, Niki M, Zhao M, Karnell FG, Clarkson B, Pear WS, Van Aelst L, Pandolfi PP. p62(dok), a negative regulator of Ras and mitogen-activated protein kinase (MAPK) activity, opposes leukemogenesis by p210(bcr-abl). The Journal of Experimental Medicine. 194: 275-84. PMID 11489947 DOI: 10.1084/Jem.194.3.275  0.444
2001 Zhao M, Schmitz AA, Qin Y, Di Cristofano A, Pandolfi PP, Van Aelst L. Phosphoinositide 3-kinase-dependent membrane recruitment of p62(dok) is essential for its negative effect on mitogen-activated protein (MAP) kinase activation. The Journal of Experimental Medicine. 194: 265-74. PMID 11489946 DOI: 10.1084/Jem.194.3.265  0.488
2000 Schmitz AA, Govek EE, Böttner B, Van Aelst L. Rho GTPases: signaling, migration, and invasion. Experimental Cell Research. 261: 1-12. PMID 11082269 DOI: 10.1006/excr.2000.5049  0.697
2000 Boettner B, Govek EE, Cross J, Van Aelst L. The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin. Proceedings of the National Academy of Sciences of the United States of America. 97: 9064-9. PMID 10922060 DOI: 10.1073/Pnas.97.16.9064  0.738
2000 Li Z, Van Aelst L, Cline HT. Rho GTPases regulate distinct aspects of dendritic arbor growth in Xenopus central neurons in vivo. Nature Neuroscience. 3: 217-25. PMID 10700252 DOI: 10.1038/72920  0.339
1998 Webb CP, Van Aelst L, Wigler MH, Vande Woude GF. Signaling pathways in Ras-mediated tumorigenicity and metastasis. Proceedings of the National Academy of Sciences of the United States of America. 95: 8773-8. PMID 9671754 DOI: 10.1073/pnas.95.15.8773  0.557
1997 Van Aelst L, D'Souza-Schorey C. Rho GTPases and signaling networks. Genes & Development. 11: 2295-322. PMID 9308960 DOI: 10.1101/Gad.11.18.2295  0.332
1997 Westwick JK, Lambert QT, Clark GJ, Symons M, Van Aelst L, Pestell RG, Der CJ. Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways. Molecular and Cellular Biology. 17: 1324-35. PMID 9032259 DOI: 10.1128/Mcb.17.3.1324  0.332
1996 Joneson T, McDonough M, Bar-Sagi D, Van Aelst L. RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase. Science (New York, N.Y.). 274: 1374-6. PMID 8910277 DOI: 10.1126/Science.274.5291.1374  0.707
1996 Barr MM, Tu H, Van Aelst L, Wigler M. Identification of Ste4 as a potential regulator of Byr2 in the sexual response pathway of Schizosaccharomyces pombe. Molecular and Cellular Biology. 16: 5597-603. PMID 8816472 DOI: 10.1128/Mcb.16.10.5597  0.513
1996 Khosravi-Far R, White MA, Westwick JK, Solski PA, Chrzanowska-Wodnicka M, Van Aelst L, Wigler MH, Der CJ. Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation. Molecular and Cellular Biology. 16: 3923-33. PMID 8668210 DOI: 10.1128/Mcb.16.7.3923  0.554
1995 White MA, Nicolette C, Minden A, Polverino A, Van Aelst L, Karin M, Wigler MH. Multiple Ras functions can contribute to mammalian cell transformation. Cell. 80: 533-41. PMID 7867061 DOI: 10.1016/0092-8674(95)90507-3  0.528
1994 Jung V, Wei W, Ballester R, Camonis J, Mi S, Van Aelst L, Wigler M, Broek D. Two types of RAS mutants that dominantly interfere with activators of RAS. Molecular and Cellular Biology. 14: 3707-18. PMID 8196614 DOI: 10.1128/Mcb.14.6.3707  0.518
1994 Van Aelst L, White MA, Wigler MH. Ras partners. Cold Spring Harbor Symposia On Quantitative Biology. 59: 181-6. PMID 7587068  0.489
1993 Chardin P, Camonis JH, Gale NW, van Aelst L, Schlessinger J, Wigler MH, Bar-Sagi D. Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2. Science (New York, N.Y.). 260: 1338-43. PMID 8493579 DOI: 10.1126/Science.8493579  0.557
1993 Van Aelst L, Barr M, Marcus S, Polverino A, Wigler M. Complex formation between RAS and RAF and other protein kinases. Proceedings of the National Academy of Sciences of the United States of America. 90: 6213-7. PMID 8327501 DOI: 10.1073/Pnas.90.13.6213  0.561
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