| Year |
Citation |
Score |
| 2023 |
Heydenreich FM, Marti-Solano M, Sandhu M, Kobilka BK, Bouvier M, Babu MM. Molecular determinants of ligand efficacy and potency in GPCR signaling. Science (New York, N.Y.). 382: eadh1859. PMID 38127743 DOI: 10.1126/science.adh1859 |
0.709 |
|
| 2022 |
Paradis JS, Feng X, Murat B, Jefferson RE, Sokrat B, Szpakowska M, Hogue M, Bergkamp ND, Heydenreich FM, Smit MJ, Chevigné A, Bouvier M, Barth P. Computationally designed GPCR quaternary structures bias signaling pathway activation. Nature Communications. 13: 6826. PMID 36369272 DOI: 10.1038/s41467-022-34382-7 |
0.722 |
|
| 2022 |
Janetzko J, Kise R, Barsi-Rhyne B, Siepe DH, Heydenreich FM, Kawakami K, Masureel M, Maeda S, Garcia KC, von Zastrow M, Inoue A, Kobilka BK. Membrane phosphoinositides regulate GPCR-β-arrestin complex assembly and dynamics. Cell. PMID 36368322 DOI: 10.1016/j.cell.2022.10.018 |
0.545 |
|
| 2022 |
Heydenreich FM, Plouffe B, Rizk A, Milic D, Zhou J, Breton B, Le Gouill C, Inoue A, Bouvier M, Veprintsev D. . Molecular Pharmacology. PMID 35779859 DOI: 10.1124/molpharm.122.000497 |
0.649 |
|
| 2022 |
Hedderich JB, Persechino M, Becker K, Heydenreich FM, Gutermuth T, Bouvier M, Bünemann M, Kolb P. The pocketome of G-protein-coupled receptors reveals previously untargeted allosteric sites. Nature Communications. 13: 2567. PMID 35538063 DOI: 10.1038/s41467-022-29609-6 |
0.641 |
|
| 2021 |
Harwood CR, Sykes DA, Hoare BL, Heydenreich FM, Uddin R, Poyner DR, Briddon SJ, Veprintsev DB. Functional solubilization of the β-adrenoceptor using diisobutylene maleic acid. Iscience. 24: 103362. PMID 34825145 DOI: 10.1016/j.isci.2021.103362 |
0.369 |
|
| 2021 |
Hauser AS, Kooistra AJ, Munk C, Heydenreich FM, Veprintsev DB, Bouvier M, Babu MM, Gloriam DE. GPCR activation mechanisms across classes and macro/microscales. Nature Structural & Molecular Biology. 28: 879-888. PMID 34759375 DOI: 10.1038/s41594-021-00674-7 |
0.608 |
|
| 2020 |
Latorraca NR, Masureel M, Hollingsworth SA, Heydenreich FM, Suomivuori CM, Brinton C, Townshend RJL, Bouvier M, Kobilka BK, Dror RO. How GPCR Phosphorylation Patterns Orchestrate Arrestin-Mediated Signaling. Cell. PMID 33296703 DOI: 10.1016/j.cell.2020.11.014 |
0.574 |
|
| 2017 |
Gosztolai A, Schumacher J, Behrends V, Bundy JG, Heydenreich F, Bennett MH, Buck M, Barahona M. GlnK Facilitates the Dynamic Regulation of Bacterial Nitrogen Assimilation. Biophysical Journal. 112: 2219-2230. PMID 28538158 DOI: 10.1016/J.Bpj.2017.04.012 |
0.332 |
|
| 2017 |
Beautrait A, Paradis JS, Zimmerman B, Giubilaro J, Nikolajev L, Armando S, Kobayashi H, Yamani L, Namkung Y, Heydenreich FM, Khoury E, Audet M, Roux PP, Veprintsev DB, Laporte SA, et al. A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling. Nature Communications. 8: 15054. PMID 28416805 DOI: 10.1038/Ncomms15054 |
0.595 |
|
| 2016 |
Venkatakrishnan AJ, Deupi X, Lebon G, Heydenreich FM, Flock T, Miljus T, Balaji S, Bouvier M, Veprintsev DB, Tate CG, Schertler GF, Babu MM. Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region. Nature. PMID 27525504 DOI: 10.1038/Nature19107 |
0.706 |
|
| 2016 |
Thomsen AR, Plouffe B, Cahill TJ, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, et al. GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling. Cell. PMID 27499021 DOI: 10.1016/J.Cell.2016.07.004 |
0.796 |
|
| 2016 |
Isogai S, Deupi X, Opitz C, Heydenreich FM, Tsai CJ, Brueckner F, Schertler GF, Veprintsev DB, Grzesiek S. Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor. Nature. PMID 26840483 DOI: 10.1038/nature16577 |
0.636 |
|
| 2015 |
Heydenreich FM, Vuckovic Z, Matkovic M, Veprintsev DB. Stabilization of G protein-coupled receptors by point mutations. Frontiers in Pharmacology. 6: 82. PMID 25941489 DOI: 10.3389/fphar.2015.00082 |
0.433 |
|
| 2013 |
Schumacher J, Behrends V, Pan Z, Brown DR, Heydenreich F, Lewis MR, Bennett MH, Razzaghi B, Komorowski M, Barahona M, Stumpf MP, Wigneshweraraj S, Bundy JG, Buck M. Nitrogen and carbon status are integrated at the transcriptional level by the nitrogen regulator NtrC in vivo. Mbio. 4: e00881-13. PMID 24255125 DOI: 10.1128/Mbio.00881-13 |
0.322 |
|
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