Anne-Claude Gavin - Publications

Affiliations: 
Structural and Computational Biology Unit EMBL Heidelberg 

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Year Citation  Score
2021 Li Y, Kuhn M, Zukowska-Kasprzyk J, Hennrich ML, Kastritis PL, O'Reilly FJ, Phapale P, Beck M, Gavin AC, Bork P. Coupling proteomics and metabolomics for the unsupervised identification of protein-metabolite interactions in Chaetomium thermophilum. Plos One. 16: e0254429. PMID 34242379 DOI: 10.1371/journal.pone.0254429  0.632
2018 Kastritis PL, Gavin AC. Enzymatic complexes across scales. Essays in Biochemistry. 62: 501-514. PMID 30315098 DOI: 10.1042/Ebc20180008  0.561
2017 Kastritis PL, O'Reilly FJ, Bock T, Li Y, Rogon MZ, Buczak K, Romanov N, Betts MJ, Bui KH, Hagen WJ, Hennrich ML, Mackmull MT, Rappsilber J, Russell RB, Bork P, ... ... Gavin AC, et al. Capturing protein communities by structural proteomics in a thermophilic eukaryote. Molecular Systems Biology. 13: 936. PMID 28743795 DOI: 10.15252/Msb.20167412  0.648
2014 Bock T, Chen WH, Ori A, Malik N, Silva-Martin N, Huerta-Cepas J, Powell ST, Kastritis PL, Smyshlyaev G, Vonkova I, Kirkpatrick J, Doerks T, Nesme L, Baßler J, Kos M, ... ... Gavin AC, et al. An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum. Nucleic Acids Research. 42: 13525-33. PMID 25398899 DOI: 10.1093/Nar/Gku1147  0.616
2012 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, ... ... Gavin AC, et al. Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium. Molecular Systems Biology. 8: 571. PMID 22373819 DOI: 10.1038/Msb.2012.4  0.339
1999 Nebreda AR, Gavin AC. Perspectives: signal transduction. Cell survival demands some Rsk. Science (New York, N.Y.). 286: 1309-10. PMID 10610536 DOI: 10.1126/SCIENCE.286.5443.1309  0.433
1999 Gavin AC, Ni Ainle A, Chierici E, Jones M, Nebreda AR. A p90(rsk) mutant constitutively interacting with MAP kinase uncouples MAP kinase from p34(cdc2)/cyclin B activation in Xenopus oocytes. Molecular Biology of the Cell. 10: 2971-86. PMID 10473640 DOI: 10.1091/MBC.10.9.2971  0.557
1999 Dorey K, Barilá D, Gavin AC, Nebreda AR, Superti-Furga G. Regulation of human c-Abl tyrosine kinase activity in Xenopus oocytes and acceleration of progesterone-induced G2/M transition by oncogenic forms. Biological Chemistry. 380: 223-30. PMID 10195429 DOI: 10.1515/BC.1999.030  0.603
1999 Gavin AC, Nebreda AR. A MAP kinase docking site is required for phosphorylation and activation of p90(rsk)/MAPKAP kinase-1. Current Biology : Cb. 9: 281-4. PMID 10074458 DOI: 10.1016/S0960-9822(99)80120-1  0.575
1998 Palmer A, Gavin AC, Nebreda AR. A link between MAP kinase and p34(cdc2)/cyclin B during oocyte maturation: p90(rsk) phosphorylates and inactivates the p34(cdc2) inhibitory kinase Myt1. The Embo Journal. 17: 5037-47. PMID 9724639 DOI: 10.1093/emboj/17.17.5037  0.58
1997 Gavin AC, Schorderet-Slatkine S. Ribosomal S6 kinase p90rsk and mRNA cap-binding protein eIF4E phosphorylations correlate with MAP kinase activation during meiotic reinitiation of mouse oocytes. Molecular Reproduction and Development. 46: 383-91. PMID 9041142 DOI: 10.1002/(SICI)1098-2795(199703)46:3<383::AID-MRD18>3.0.CO;2-#  0.666
1996 de Vant'ery C, Gavin AC, Vassalli JD, Schorderet-Slatkine S. An accumulation of p34cdc2 at the end of mouse oocyte growth correlates with the acquisition of meiotic competence. Developmental Biology. 174: 335-44. PMID 8631505 DOI: 10.1006/dbio.1996.0078  0.668
1992 Gavin AC, Vassalli JD, Cavadore JC, Schorderet-Slatkine S. Okadaic acid and p13suc1 modulate the reinitiation of meiosis in mouse oocytes. Molecular Reproduction and Development. 33: 287-96. PMID 1333241 DOI: 10.1002/mrd.1080330309  0.679
1991 Gavin AC, Tsukitani Y, Schorderet-Slatkine S. Induction of M-phase entry of prophase-blocked mouse oocytes through microinjection of okadaic acid, a specific phosphatase inhibitor. Experimental Cell Research. 192: 75-81. PMID 1701730 DOI: 10.1016/0014-4827(91)90159-r  0.636
1988 Gavin AC, Schorderet-Slatkine S. The interaction of lithium with forskolin-inhibited meiotic maturation of denuded mouse oocytes. Experimental Cell Research. 179: 298-302. PMID 2844571 DOI: 10.1016/0014-4827(88)90369-2  0.649
Low-probability matches (unlikely to be authored by this person)
2017 Betts MJ, Wichmann O, Utz M, Andre T, Petsalaki E, Minguez P, Parca L, Roth FP, Gavin AC, Bork P, Russell RB. Systematic identification of phosphorylation-mediated protein interaction switches. Plos Computational Biology. 13: e1005462. PMID 28346509 DOI: 10.1371/Journal.Pcbi.1005462  0.3
2018 Sostaric N, O'Reilly FJ, Giansanti P, Heck AJR, Gavin AC, van Noort V. Effects of acetylation and phosphorylation on subunit interactions in three large eukaryotic complexes. Molecular & Cellular Proteomics : McP. PMID 30181345 DOI: 10.1074/mcp.RA118.000892  0.293
2023 Truebestein L, Antonioli S, Waltenberger E, Gehin C, Gavin AC, Leonard TA. Structure and regulation of the myotonic dystrophy kinase-related Cdc42-binding kinase. Structure (London, England : 1993). PMID 36854301 DOI: 10.1016/j.str.2023.02.002  0.29
2006 Cheusova T, Khan MA, Schubert SW, Gavin AC, Buchou T, Jacob G, Sticht H, Allende J, Boldyreff B, Brenner HR, Hashemolhosseini S. Casein kinase 2-dependent serine phosphorylation of MuSK regulates acetylcholine receptor aggregation at the neuromuscular junction. Genes & Development. 20: 1800-16. PMID 16818610 DOI: 10.1101/Gad.375206  0.287
2013 Gallego O, Specht T, Brach T, Kumar A, Gavin AC, Kaksonen M. Detection and characterization of protein interactions in vivo by a simple live-cell imaging method. Plos One. 8: e62195. PMID 23658712 DOI: 10.1371/Journal.Pone.0062195  0.28
2011 Maier T, Schmidt A, Güell M, Kühner S, Gavin AC, Aebersold R, Serrano L. Quantification of mRNA and protein and integration with protein turnover in a bacterium. Molecular Systems Biology. 7: 511. PMID 21772259 DOI: 10.1038/Msb.2011.38  0.279
2006 Gavin AC, Aloy P, Grandi P, Krause R, Boesche M, Marzioch M, Rau C, Jensen LJ, Bastuck S, Dümpelfeld B, Edelmann A, Heurtier MA, Hoffman V, Hoefert C, Klein K, et al. Proteome survey reveals modularity of the yeast cell machinery. Nature. 440: 631-6. PMID 16429126 DOI: 10.1038/Nature04532  0.272
2002 Gavin AC, Bösche M, Krause R, Grandi P, Marzioch M, Bauer A, Schultz J, Rick JM, Michon AM, Cruciat CM, Remor M, Höfert C, Schelder M, Brajenovic M, Ruffner H, et al. Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature. 415: 141-7. PMID 11805826 DOI: 10.1038/415141A  0.261
2006 Gavin AC, Hopf C. Protein co-membership and biochemical affinity purifications. Drug Discovery Today. Technologies. 3: 325-30. PMID 24980536 DOI: 10.1016/j.ddtec.2006.07.001  0.26
2011 Gavin AC, Maeda K, Kühner S. Recent advances in charting protein-protein interaction: mass spectrometry-based approaches. Current Opinion in Biotechnology. 22: 42-9. PMID 20934865 DOI: 10.1016/j.copbio.2010.09.007  0.259
2015 Haberkant P, Stein F, Höglinger D, Gerl MJ, Brügger B, Van Veldhoven PP, Krijgsveld J, Gavin AC, Schultz C. Bifunctional Sphingosine for Cell-Based Analysis of Protein-Sphingolipid Interactions. Acs Chemical Biology. PMID 26555438 DOI: 10.1021/acschembio.5b00810  0.258
2015 Glatt S, Zabel R, Vonkova I, Kumar A, Netz DJ, Pierik AJ, Rybin V, Lill R, Gavin AC, Balbach J, Breunig KD, Müller CW. heterodimer and its double role in modificationsStructure of the Kti11/Kti13 of tRNA and eukaryotic elongation factor 2. Structure (London, England : 1993). 23: 149-60. PMID 25543256 DOI: 10.1016/J.Str.2014.11.008  0.253
2003 Gavin AC, Superti-Furga G. Protein complexes and proteome organization from yeast to man. Current Opinion in Chemical Biology. 7: 21-7. PMID 12547422 DOI: 10.1016/s1367-5931(02)00007-8  0.251
2015 Hennrich ML, Gavin AC. Quantitative mass spectrometry of posttranslational modifications: keys to confidence. Science Signaling. 8: re5. PMID 25852188 DOI: 10.1126/scisignal.aaa6466  0.243
2013 Taylor NM, Glatt S, Hennrich ML, von Scheven G, Grötsch H, Fernández-Tornero C, Rybin V, Gavin AC, Kolb P, Müller CW. Structural and functional characterization of a phosphatase domain within yeast general transcription factor IIIC. The Journal of Biological Chemistry. 288: 15110-20. PMID 23569204 DOI: 10.1074/Jbc.M112.427856  0.237
2012 Minguez P, Parca L, Diella F, Mende DR, Kumar R, Helmer-Citterich M, Gavin AC, van Noort V, Bork P. Deciphering a global network of functionally associated post-translational modifications. Molecular Systems Biology. 8: 599. PMID 22806145 DOI: 10.1038/Msb.2012.31  0.233
2020 Sajko S, Grishkovskaya I, Kostan J, Graewert M, Setiawan K, Trübestein L, Niedermüller K, Gehin C, Sponga A, Puchinger M, Gavin AC, Leonard TA, Svergun DI, Smith TK, Morriswood B, et al. Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats. Plos One. 15: e0242677. PMID 33296386 DOI: 10.1371/journal.pone.0242677  0.232
2015 Betts MJ, Lu Q, Jiang Y, Drusko A, Wichmann O, Utz M, Valtierra-Gutiérrez IA, Schlesner M, Jaeger N, Jones DT, Pfister S, Lichter P, Eils R, Siebert R, Bork P, ... ... Gavin AC, et al. Mechismo: predicting the mechanistic impact of mutations and modifications on molecular interactions. Nucleic Acids Research. 43: e10. PMID 25392414 DOI: 10.1093/Nar/Gku1094  0.228
2018 Boulter E, Estrach S, Tissot FS, Hennrich ML, Tosello L, Cailleteau L, de la Ballina LR, Pisano S, Gavin AC, Féral CC. Cell metabolism regulates integrin mechanosensing via an SLC3A2-dependent sphingolipid biosynthesis pathway. Nature Communications. 9: 4862. PMID 30451822 DOI: 10.1038/S41467-018-07268-W  0.224
2009 Kühner S, van Noort V, Betts MJ, Leo-Macias A, Batisse C, Rode M, Yamada T, Maier T, Bader S, Beltran-Alvarez P, Castaño-Diez D, Chen WH, Devos D, Güell M, Norambuena T, ... ... Gavin AC, et al. Proteome organization in a genome-reduced bacterium. Science (New York, N.Y.). 326: 1235-40. PMID 19965468 DOI: 10.1126/Science.1176343  0.215
2007 Gavin A, Aloy P, Russell RB, Superti‐Furga G. Systems‐wide analysis of protein complexes in Saccharomyces cerevisiae The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A211-D  0.211
2015 Paul VD, Mühlenhoff U, Stümpfig M, Seebacher J, Kugler KG, Renicke C, Taxis C, Gavin AC, Pierik AJ, Lill R. The deca-GX3 proteins Yae1-Lto1 function as adaptors recruiting the ABC protein Rli1 for iron-sulfur cluster insertion. Elife. 4: e08231. PMID 26182403 DOI: 10.7554/eLife.08231  0.209
2014 Maeda K, Poletto M, Chiapparino A, Gavin AC. A generic protocol for the purification and characterization of water-soluble complexes of affinity-tagged proteins and lipids. Nature Protocols. 9: 2256-66. PMID 25167057 DOI: 10.1038/nprot.2014.148  0.206
2013 Maeda K, Anand K, Chiapparino A, Kumar A, Poletto M, Kaksonen M, Gavin AC. Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins. Nature. 501: 257-61. PMID 23934110 DOI: 10.1038/Nature12430  0.206
2016 Saliba AE, Vonkova I, Deghou S, Ceschia S, Tischer C, Kugler KG, Bork P, Ellenberg J, Gavin AC. A protocol for the systematic and quantitative measurement of protein-lipid interactions using the liposome-microarray-based assay. Nature Protocols. 11: 1021-38. PMID 27149326 DOI: 10.1038/Nprot.2016.059  0.205
2004 Aloy P, Böttcher B, Ceulemans H, Leutwein C, Mellwig C, Fischer S, Gavin AC, Bork P, Superti-Furga G, Serrano L, Russell RB. Structure-based assembly of protein complexes in yeast. Science (New York, N.Y.). 303: 2026-9. PMID 15044803 DOI: 10.1126/Science.1092645  0.205
2010 Gallego O, Betts MJ, Gvozdenovic-Jeremic J, Maeda K, Matetzki C, Aguilar-Gurrieri C, Beltran-Alvarez P, Bonn S, Fernández-Tornero C, Jensen LJ, Kuhn M, Trott J, Rybin V, Müller CW, Bork P, ... ... Gavin AC, et al. A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae. Molecular Systems Biology. 6: 430. PMID 21119626 DOI: 10.1038/Msb.2010.87  0.2
2008 Charbonnier S, Gallego O, Gavin AC. The social network of a cell: recent advances in interactome mapping. Biotechnology Annual Review. 14: 1-28. PMID 18606358 DOI: 10.1016/S1387-2656(08)00001-X  0.198
2008 Bader S, Kühner S, Gavin AC. Interaction networks for systems biology. Febs Letters. 582: 1220-4. PMID 18282471 DOI: 10.1016/j.febslet.2008.02.015  0.19
2011 Seebacher J, Gavin AC. SnapShot: Protein-protein interaction networks. Cell. 144: 1000, 1000.e1. PMID 21414489 DOI: 10.1016/j.cell.2011.02.025  0.184
2014 Saliba AE, Vonkova I, Ceschia S, Findlay GM, Maeda K, Tischer C, Deghou S, van Noort V, Bork P, Pawson T, Ellenberg J, Gavin AC. A quantitative liposome microarray to systematically characterize protein-lipid interactions. Nature Methods. 11: 47-50. PMID 24270602 DOI: 10.1038/Nmeth.2734  0.178
2021 Roy S, Sipthorp J, Mahata B, Pramanik J, Hennrich ML, Gavin AC, Ley SV, Teichmann SA. CLICK-enabled analogues reveal pregnenolone interactomes in cancer and immune cells. Iscience. 24: 102485. PMID 34036248 DOI: 10.1016/j.isci.2021.102485  0.177
2016 Chen WH, van Noort V, Lluch-Senar M, Hennrich ML, H Wodke JA, Yus E, Alibés A, Roma G, Mende DR, Pesavento C, Typas A, Gavin AC, Serrano L, Bork P. Integration of multi-omics data of a genome-reduced bacterium: Prevalence of post-transcriptional regulation and its correlation with protein abundances. Nucleic Acids Research. PMID 26773059 DOI: 10.1093/Nar/Gkw004  0.172
2016 Ho AD, Horn P, Hennrich M, Jaeger S, Romanov N, Ding X, Bork P, Aloy P, Gavin A. Proteomics Analysis of Cellular Network in Human Bone Marrow Reveals Lineage Skewing Towards Megakaryocytes and Decrease in Lymphoid Development upon Aging Blood. 128: 2658-2658. DOI: 10.1182/Blood.V128.22.2658.2658  0.171
2004 Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J, Ghidelli S, Hopf C, Huhse B, Mangano R, Michon AM, Schirle M, ... ... Gavin AC, et al. A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. Nature Cell Biology. 6: 97-105. PMID 14743216 DOI: 10.1038/ncb1086  0.169
2013 Haberkant P, Raijmakers R, Wildwater M, Sachsenheimer T, Brügger B, Maeda K, Houweling M, Gavin AC, Schultz C, van Meer G, Heck AJ, Holthuis JC. In vivo profiling and visualization of cellular protein-lipid interactions using bifunctional fatty acids. Angewandte Chemie (International Ed. in English). 52: 4033-8. PMID 23450850 DOI: 10.1002/Anie.201210178  0.169
2017 Reckel S, Gehin C, Tardivon D, Georgeon S, Kükenshöner T, Löhr F, Koide A, Buchner L, Panjkovich A, Reynaud A, Pinho S, Gerig B, Svergun D, Pojer F, Güntert P, ... ... Gavin AC, et al. Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase. Nature Communications. 8: 2101. PMID 29235475 DOI: 10.1038/S41467-017-02313-6  0.167
2020 Wang Y, Rohde C, Zhou F, Hennrich M, Poisa-Beiro L, Eckstein V, Pabst C, Gavin A, Ho AD, Müller-Tidow C. The Ribomethylome Landscape of Hematopoietic System Blood. 136: 41-42. DOI: 10.1182/BLOOD-2020-136522  0.164
2023 Roy S, Roy S, Mahata B, Pramanik J, Hennrich ML, Gavin AC, Teichmann SA. CLICK-chemoproteomics and molecular dynamics simulation reveals pregnenolone targets and their binding conformations in Th2 cells. Frontiers in Immunology. 14: 1229703. PMID 38022565 DOI: 10.3389/fimmu.2023.1229703  0.162
2022 Poisa-Beiro L, Landry JJM, Raffel S, Tanaka M, Zaugg J, Gavin AC, Ho AD. Glucose Metabolism and Aging of Hematopoietic Stem and Progenitor Cells. International Journal of Molecular Sciences. 23. PMID 35328449 DOI: 10.3390/ijms23063028  0.16
2013 Kuhn M, Al Banchaabouchi M, Campillos M, Jensen LJ, Gross C, Gavin AC, Bork P. Systematic identification of proteins that elicit drug side effects. Molecular Systems Biology. 9: 663. PMID 23632385 DOI: 10.1038/Msb.2013.10  0.159
2002 Grandi P, Rybin V, Bassler J, Petfalski E, Strauss D, Marzioch M, Schäfer T, Kuster B, Tschochner H, Tollervey D, Gavin AC, Hurt E. 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Molecular Cell. 10: 105-15. PMID 12150911 DOI: 10.1016/S1097-2765(02)00579-8  0.154
2015 Lluch-Senar M, Delgado J, Chen WH, Lloréns-Rico V, O'Reilly FJ, Wodke JA, Unal EB, Yus E, Martínez S, Nichols RJ, Ferrar T, Vivancos A, Schmeisky A, Stülke J, van Noort V, ... Gavin AC, et al. Defining a minimal cell: essentiality of small ORFs and ncRNAs in a genome-reduced bacterium. Molecular Systems Biology. 11: 780. PMID 25609650 DOI: 10.15252/Msb.20145558  0.154
2024 Girik V, van Ek L, Dentand Quadri I, Azam M, Cruz Cobo M, Mandavit M, Riezman I, Riezman H, Gavin AC, Nunes-Hasler P. Development of Genetically Encoded Fluorescent KSR1-Based Probes to Track Ceramides during Phagocytosis. International Journal of Molecular Sciences. 25. PMID 38474242 DOI: 10.3390/ijms25052996  0.153
2018 Hennrich ML, Romanov N, Horn P, Jaeger S, Eckstein V, Poisa-Beiro L, Boultwood J, Luft T, Pellagatti A, Bork P, Aloy P, Gavin A, Ho AD. Proteome Analyses and Single-Cell RNA Sequencing Reveal Age-Dependent Re-Wiring of Central Carbon Metabolism in Myeloid-Biased Subsets of Human Hematopoietic Stem Cells Blood. 132: 873-873. DOI: 10.1182/Blood-2018-99-110787  0.151
2023 Vanni E, Lindner K, Gavin AC, Montessuit C. Differential intracellular management of fatty acids impacts on metabolic stress-stimulated glucose uptake in cardiomyocytes. Scientific Reports. 13: 14805. PMID 37684349 DOI: 10.1038/s41598-023-42072-7  0.149
2020 Wong M, Newton LR, Hartmann J, Hennrich ML, Wachsmuth M, Ronchi P, Guzmán-Herrera A, Schwab Y, Gavin AC, Gilmour D. Dynamic Buffering of Extracellular Chemokine by a Dedicated Scavenger Pathway Enables Robust Adaptation during Directed Tissue Migration. Developmental Cell. PMID 32059773 DOI: 10.1016/J.Devcel.2020.01.013  0.146
2015 Saliba AE, Vonkova I, Gavin AC. The systematic analysis of protein-lipid interactions comes of age Nature Reviews Molecular Cell Biology. 16: 753-761. PMID 26507169 DOI: 10.1038/nrm4080  0.144
2013 Iskar M, Zeller G, Blattmann P, Campillos M, Kuhn M, Kaminska KH, Runz H, Gavin AC, Pepperkok R, van Noort V, Bork P. Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding. Molecular Systems Biology. 9: 662. PMID 23632384 DOI: 10.1038/Msb.2013.20  0.139
2009 Yus E, Maier T, Michalodimitrakis K, van Noort V, Yamada T, Chen WH, Wodke JA, Güell M, Martínez S, Bourgeois R, Kühner S, Raineri E, Letunic I, Kalinina OV, Rode M, ... ... Gavin AC, et al. Impact of genome reduction on bacterial metabolism and its regulation. Science (New York, N.Y.). 326: 1263-8. PMID 19965476 DOI: 10.1126/Science.1177263  0.138
2016 Chiapparino A, Maeda K, Turei D, Saez-Rodriguez J, Gavin AC. The orchestra of lipid-transfer proteins at the crossroads between metabolism and signaling. Progress in Lipid Research. 61: 30-9. PMID 26658141 DOI: 10.1016/J.Plipres.2015.10.004  0.138
2012 Bonn S, Zinzen RP, Perez-Gonzalez A, Riddell A, Gavin AC, Furlong EE. Cell type-specific chromatin immunoprecipitation from multicellular complex samples using BiTS-ChIP. Nature Protocols. 7: 978-94. PMID 22538849 DOI: 10.1038/Nprot.2012.049  0.138
2009 Güell M, van Noort V, Yus E, Chen WH, Leigh-Bell J, Michalodimitrakis K, Yamada T, Arumugam M, Doerks T, Kühner S, Rode M, Suyama M, Schmidt S, Gavin AC, Bork P, et al. Transcriptome complexity in a genome-reduced bacterium. Science (New York, N.Y.). 326: 1268-71. PMID 19965477 DOI: 10.1126/Science.1176951  0.134
2016 Luján P, Varsano G, Rubio T, Hennrich ML, Sachsenheimer T, Gálvez-Santisteban M, Martín-Belmonte F, Gavin AC, Brügger B, Köhn M. PRL-3 disrupts epithelial architecture by altering the post-mitotic midbody position. Journal of Cell Science. 129: 4130-4142. PMID 27656108 DOI: 10.1242/jcs.190215  0.134
2016 Chiapparino A, Maeda K, Turei D, Saez-Rodriguez J, Gavin AC. The orchestra of lipid-transfer proteins at the crossroads between metabolism and signaling Progress in Lipid Research. 61: 30-39. DOI: 10.1016/j.plipres.2015.10.004  0.133
2011 Lane LA, Fernández-Tornero C, Zhou M, Morgner N, Ptchelkine D, Steuerwald U, Politis A, Lindner D, Gvozdenovic J, Gavin AC, Müller CW, Robinson CV. Mass spectrometry reveals stable modules in holo and apo RNA polymerases I and III. Structure (London, England : 1993). 19: 90-100. PMID 21220119 DOI: 10.1016/j.str.2010.11.009  0.132
2018 Hennrich ML, Romanov N, Horn P, Jaeger S, Eckstein V, Steeples V, Ye F, Ding X, Poisa-Beiro L, Lai MC, Lang B, Boultwood J, Luft T, Zaugg JB, Pellagatti A, ... ... Gavin AC, et al. Cell-specific proteome analyses of human bone marrow reveal molecular features of age-dependent functional decline. Nature Communications. 9: 4004. PMID 30275468 DOI: 10.1038/S41467-018-06353-4  0.131
2020 Liu Y, Bunney TD, Khosa S, Macé K, Beckenbauer K, Askwith T, Maslen S, Stubbs C, de Oliveira TM, Sader K, Skehel M, Gavin AC, Phillips C, Katan M. Structural insights and activating mutations in diverse pathologies define mechanisms of deregulation for phospholipase C gamma enzymes. Ebiomedicine. 51: 102607. PMID 31918402 DOI: 10.1016/j.ebiom.2019.102607  0.123
2018 Pellagatti A, Armstrong RN, Steeples V, Sharma E, Repapi E, Singh S, Sanchi A, Radujkovic A, Horn P, Dolatshad H, Roy S, Broxholme J, Lockstone H, Taylor S, Giagounidis A, ... ... Gavin AC, et al. Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations. Blood. PMID 29930011 DOI: 10.1182/Blood-2018-04-843771  0.122
2024 Talandashti R, van Ek L, Gehin C, Xue D, Moqadam M, Gavin AC, Reuter N. Membrane specificity of the human cholesterol transfer protein STARD4. Journal of Molecular Biology. 168572. PMID 38615744 DOI: 10.1016/j.jmb.2024.168572  0.12
2024 Lindner K, Gavin AC. Isoform- and cell-state-specific APOE homeostasis and function. Neural Regeneration Research. 19: 2456-2466. PMID 38526282 DOI: 10.4103/NRR.NRR-D-23-01470  0.12
2014 Gavin AC, Heck A. Expanding the frontiers in proteomics. Drug Discovery Today. Technologies. 3: 315-6. PMID 24980534 DOI: 10.1016/J.Ddtec.2006.09.016  0.118
2010 Gehlenborg N, O'Donoghue SI, Baliga NS, Goesmann A, Hibbs MA, Kitano H, Kohlbacher O, Neuweger H, Schneider R, Tenenbaum D, Gavin AC. Visualization of omics data for systems biology. Nature Methods. 7: S56-68. PMID 20195258 DOI: 10.1038/Nmeth.1436  0.116
2015 Vonkova I, Saliba AE, Deghou S, Anand K, Ceschia S, Doerks T, Galih A, Kugler KG, Maeda K, Rybin V, van Noort V, Ellenberg J, Bork P, Gavin AC. Lipid Cooperativity as a General Membrane-Recruitment Principle for PH Domains. Cell Reports. 12: 1519-30. PMID 26299969 DOI: 10.1016/J.Celrep.2015.07.054  0.113
2007 Orchard S, Salwinski L, Kerrien S, Montecchi-Palazzi L, Oesterheld M, Stümpflen V, Ceol A, Chatr-aryamontri A, Armstrong J, Woollard P, Salama JJ, Moore S, Wojcik J, Bader GD, Vidal M, ... ... Gavin AC, et al. The minimum information required for reporting a molecular interaction experiment (MIMIx). Nature Biotechnology. 25: 894-8. PMID 17687370 DOI: 10.1038/Nbt1324  0.113
2008 Gavin AC, Aebersold R, Heck AJ. Meeting report on the 7th World Congress of the Human Proteome Organization (HUPO) in Amsterdam: Proteome Biology. Molecular & Cellular Proteomics : McP. 7: 2288-91. PMID 18996833 DOI: 10.1074/Mcp.H800011-Mcp200  0.11
2014 Gustafsson M, Nestor CE, Zhang H, Barabási AL, Baranzini S, Brunak S, Chung KF, Federoff HJ, Gavin AC, Meehan RR, Picotti P, Pujana MÀ, Rajewsky N, Smith KG, Sterk PJ, et al. Modules, networks and systems medicine for understanding disease and aiding diagnosis. Genome Medicine. 6: 82. PMID 25473422 DOI: 10.1186/S13073-014-0082-6  0.105
2015 Lluch-Senar M, Delgado J, Chen WH, Lloréns-Rico V, O'Reilly FJ, Wodke JAH, Unal EB, Yus E, Martínez S, Nichols RJ, Ferrar T, Vivancos A, Schmeisky A, Stülke J, Van Noort V, ... Gavin AC, et al. Defining a minimal cell: Essentiality of small ORFs and ncRNAs in a genome-reduced bacterium Molecular Systems Biology. 11. DOI: 10.15252/msb.20145558  0.104
2022 Lindner K, Beckenbauer K, van Ek LC, Titeca K, de Leeuw SM, Awwad K, Hanke F, Korepanova AV, Rybin V, van der Kam EL, Mohler EG, Tackenberg C, Lakics V, Gavin AC. Isoform- and cell-state-specific lipidation of ApoE in astrocytes. Cell Reports. 38: 110435. PMID 35235798 DOI: 10.1016/j.celrep.2022.110435  0.101
2002 Aloy P, Ciccarelli FD, Leutwein C, Gavin AC, Superti-Furga G, Bork P, Bottcher B, Russell RB. A complex prediction: three-dimensional model of the yeast exosome. Embo Reports. 3: 628-35. PMID 12101094 DOI: 10.1093/Embo-Reports/Kvf135  0.1
2020 Poisa-Beiro L, Thoma J, Landry J, Sauer S, Yamamoto A, Eckstein V, Romanov N, Raffel S, Hoffmann GF, Bork P, Benes V, Gavin AC, Tanaka M, Ho AD. Glycogen accumulation, central carbon metabolism, and aging of hematopoietic stem and progenitor cells. Scientific Reports. 10: 11597. PMID 32665666 DOI: 10.1038/S41598-020-68396-2  0.094
2012 Yus E, Güell M, Vivancos AP, Chen WH, Lluch-Senar M, Delgado J, Gavin AC, Bork P, Serrano L. Transcription start site associated RNAs in bacteria. Molecular Systems Biology. 8: 585. PMID 22617959 DOI: 10.1038/Msb.2012.16  0.093
2015 Köberlin MS, Snijder B, Heinz LX, Baumann CL, Fauster A, Vladimer GI, Gavin AC, Superti-Furga G. A Conserved Circular Network of Coregulated Lipids Modulates Innate Immune Responses. Cell. 162: 170-83. PMID 26095250 DOI: 10.1016/j.cell.2015.05.051  0.092
2010 O'Donoghue SI, Gavin AC, Gehlenborg N, Goodsell DS, Hériché JK, Nielsen CB, North C, Olson AJ, Procter JB, Shattuck DW, Walter T, Wong B. Visualizing biological data-now and in the future. Nature Methods. 7: S2-4. PMID 20195254 DOI: 10.1038/Nmeth.F.301  0.089
2021 de Leeuw SM, Kirschner AWT, Lindner K, Rust R, Budny V, Wolski WE, Gavin AC, Nitsch RM, Tackenberg C. APOE2, E3, and E4 differentially modulate cellular homeostasis, cholesterol metabolism, and inflammatory response in isogenic iPSC-derived astrocytes. Stem Cell Reports. PMID 34919811 DOI: 10.1016/j.stemcr.2021.11.007  0.085
2012 Anand K, Maeda K, Gavin AC. Structural analyses of the Slm1-PH domain demonstrate ligand binding in the non-canonical site. Plos One. 7: e36526. PMID 22574179 DOI: 10.1371/journal.pone.0036526  0.082
2019 Li Y, Kuhn M, Gavin AC, Bork P. Identification of metabolites from tandem mass spectra with a machine learning approach utilizing structural features. Bioinformatics (Oxford, England). PMID 31605112 DOI: 10.1093/Bioinformatics/Btz736  0.081
2005 Gavin AC. Keystone symposia: proteomics and bioinformatics and systems and biology. Expert Review of Proteomics. 2: 291-3. PMID 16000076 DOI: 10.1586/14789450.2.3.291  0.07
2022 Lindner K, van Ek LC, Awwad K, Hanke F, Korepanova AV, Rybin V, Beckenbauer K, Gavin AC. In vitro and in cellulo ApoE particle formation, isolation, and characterization. Star Protocols. 3: 101894. PMID 36595894 DOI: 10.1016/j.xpro.2022.101894  0.07
2007 Kühner S, Gavin AC. Towards quantitative analysis of proteome dynamics. Nature Biotechnology. 25: 298-300. PMID 17344880 DOI: 10.1038/nbt0307-298  0.067
2010 Sander M, Begley TJ, Desaintes C, Gavin AC, Pelroy R, Pothof J, Shiloh Y, van Gent D, Van Houten B, Yaffe M, Mullenders L. 3rd US-EU Workshop: Systems level understanding of DNA damage responses Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 692: 53-60. PMID 20727903 DOI: 10.1016/J.Mrfmmm.2010.07.012  0.063
2008 Campillos M, Kuhn M, Gavin AC, Jensen LJ, Bork P. Drug target identification using side-effect similarity. Science (New York, N.Y.). 321: 263-6. PMID 18621671 DOI: 10.1126/Science.1158140  0.06
2022 de Leeuw SM, Kirschner AWT, Lindner K, Rust R, Budny V, Wolski WE, Gavin AC, Nitsch RM, Tackenberg C. APOE2, E3, and E4 differentially modulate cellular homeostasis, cholesterol metabolism, and inflammatory response in isogenic iPSC-derived astrocytes. Stem Cell Reports. 17: 1229-1231. PMID 35545024 DOI: 10.1016/j.stemcr.2022.03.018  0.039
2007 Gallego O, Gavin AC. New perspectives on an old disease: proteomics in cancer research. Genome Biology. 8: 303. PMID 17472735 DOI: 10.1186/gb-2007-8-4-303  0.034
2013 Marcotte E, Boone C, Babu MM, Gavin AC. Network Biology editorial 2013. Molecular Biosystems. 9: 1557-8. PMID 23712464 DOI: 10.1039/C3Mb90018E  0.023
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