Xinjiang Cai, M.D, Ph.D. - Publications

Affiliations: 
2018- Division of Cardiology, Department of Medicine University of California, Los Angeles, Los Angeles, CA 
Area:
Cardiovascular Disease; Cardiovascular Biology; BMP Signaling; Vascular Calcification; Calcium Signaling
Website:
https://scholar.google.com/citations?user=_n9IXeYAAAAJ

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zhao Y, Yang Y, Wu X, Zhang L, Cai X, Ji J, Chen S, Vera A, Boström KI, Yao Y. CDK1 inhibition reduces osteogenesis in endothelial cells in vascular calcification. Jci Insight. 9. PMID 38456502 DOI: 10.1172/jci.insight.176065  0.613
2024 Zhang L, Cai X, Ma F, Qiao X, Ji J, Ma JA, Vergnes L, Zhao Y, Yao Y, Wu X, Boström KI. Two-Step Regulation by Matrix Gla Protein Cell in Brown Adipose Cell Differentiation. Molecular Metabolism. 101870. PMID 38184275 DOI: 10.1016/j.molmet.2024.101870  0.589
2023 Qiao X, Yang Y, Zhao Y, Wu X, Zhang L, Cai X, Ji J, Boström KI, Yao Y. Aurora Kinase A Regulates Cell Transitions in Glucocorticoid-Induced Bone Loss. Cells. 12. PMID 37887278 DOI: 10.3390/cells12202434  0.572
2023 Cai X, Zhao Y, Yang Y, Wu X, Zhang L, Ma JA, Ji J, Boström KI, Yao Y. GSK3β Inhibition Ameliorates Atherosclerotic Calcification. International Journal of Molecular Sciences. 24. PMID 37511396 DOI: 10.3390/ijms241411638  0.579
2023 Qiao X, Wu X, Zhao Y, Yang Y, Zhang L, Cai X, Ma JA, Ji J, Lyons K, Boström KI, Yao Y. Cell Transitions Contribute to Glucocorticoid-Induced Bone Loss. Cells. 12. PMID 37508475 DOI: 10.3390/cells12141810  0.589
2023 Boström KI, Qiao X, Zhao Y, Wu X, Zhang L, Ma JA, Ji J, Cai X, Yao Y. GSK3β Inhibition Reduced Vascular Calcification in Mice. International Journal of Molecular Sciences. 24. PMID 36983045 DOI: 10.3390/ijms24065971  0.58
2023 Wu X, Zhang D, Qiao X, Zhang L, Cai X, Ji J, Ma JA, Zhao Y, Belperio JA, Boström KI, Yao Y. Regulating the cell shift of endothelial cell-like myofibroblasts in pulmonary fibrosis. The European Respiratory Journal. PMID 36758986 DOI: 10.1183/13993003.01799-2022  0.544
2022 Cai X, Tintut Y, Demer LL. A Potential New Link Between Inflammation and Vascular Calcification. Journal of the American Heart Association. 12: e028358. PMID 36537336 DOI: 10.1161/JAHA.122.028358  0.498
2022 Yao J, Ma F, Zhang L, Zhu C, Jumabay M, Yao Z, Wang L, Cai X, Zhang D, Qiao X, Shivkumar K, Pellegrini M, Yao Y, Wu X, Boström KI. Single-Cell RNA-Seq Identifies Dynamic Cardiac Transition Program from Adipose Derived Cells Induced by Leukemia Inhibitory Factor. Stem Cells (Dayton, Ohio). PMID 35896368 DOI: 10.1093/stmcls/sxac048  0.594
2022 Cai X, Shahandeh N, Ji J, Finn JP, Fishbein GA, Biniwale RM, Ardehali A, Sayah DM, Yang EH. Ascending Aortic Pseudoaneurysm: A Rare Complication of Transcatheter Aortic Valve Replacement and Thoracic Surgery. Circulation. Cardiovascular Imaging. 15: e014076. PMID 35861982 DOI: 10.1161/CIRCIMAGING.122.014076  0.196
2022 Cai X, Allison MA, Ambale-Venkatesh B, Jorgensen NW, Lima JAC, Muse ED, McClelland RL, Shea S, Lebeche D. Resistin and risks of incident heart failure subtypes and cardiac fibrosis: the Multi-Ethnic Study of Atherosclerosis. Esc Heart Failure. PMID 35860859 DOI: 10.1002/ehf2.14064  0.583
2021 Marchant JS, Gunaratne GS, Cai X, Slama JT, Patel S. NAADP-binding proteins find their identity. Trends in Biochemical Sciences. PMID 34810081 DOI: 10.1016/j.tibs.2021.10.008  0.324
2021 Li ZH, King TP, Ayong L, Asady B, Cai X, Rahman T, Vella SA, Coppens I, Patel S, Moreno SNJ. A plastid two-pore channel essential for inter-organelle communication and growth of Toxoplasma gondii. Nature Communications. 12: 5802. PMID 34608145 DOI: 10.1038/s41467-021-25987-5  0.354
2021 Yao J, Wu X, Qiao X, Zhang D, Zhang L, Ma JA, Cai X, Boström KI, Yao Y. Shifting osteogenesis in vascular calcification. Jci Insight. PMID 33848269 DOI: 10.1172/jci.insight.143023  0.627
2020 Zhang D, Qiao X, Yao J, Zhang L, Wu X, Ma J, Cai X, Bostrom KI, Yao Y. Pronethalol Reduces Sox2 (SRY [Sex-Determining Region Y]-Box 2) to Ameliorate Vascular Calcification. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120315571. PMID 33297753 DOI: 10.1161/ATVBAHA.120.315571  0.584
2020 Qiao X, Zhang D, Zhang L, Yao J, Wu X, Cai X, Boström KI, Yao Y. Pronethalol decreases RBPJκ to reduce Sox2 in cerebral arteriovenous malformation. Vascular Medicine (London, England). 1358863X20942833. PMID 32833597 DOI: 10.1177/1358863X20942833  0.547
2019 Cai X, Huang L. Cardiac sympathetic innervation and arrhythmogenesis. The Journal of Physiology. PMID 31348525 DOI: 10.1113/JP278463  0.205
2017 Al-Hraishawi H, Dellatore PJ, Cai X, Wang X. Intact parathyroid hormone levels and primary hyperparathyroidism. Endocrine Research. 1-5. PMID 28318329 DOI: 10.1080/07435800.2017.1292528  0.186
2017 Chung JJ, Miki K, Kim D, Shim SH, Shi HF, Hwang JY, Cai X, Iseri Y, Zhuang X, Clapham DE. CatSperζ regulates the structural continuity of sperm Ca(2+) signaling domains and is required for normal fertility. Elife. 6. PMID 28226241 DOI: 10.7554/Elife.23082  0.297
2016 Mewani V, Dhillon S, Cai X, Wang X. Transient Primary Hyperparathyroidism: A Case Report Aace Clinical Case Reports. 2: e182-e185. DOI: 10.4158/EP15779.CR  0.195
2015 Hu S, Cai X, Mewani V, Trooskin S, Wang X. IMPACT OF ETHNIC BACKGROUND ON CLINICAL CHARACTERISTICS AND CARDIOVASCULAR RISK FACTORS AMONG PATIENTS WITH PRIMARY HYPERPARATHYROIDISM. Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. PMID 26536140 DOI: 10.4158/EP15951.OR  0.2
2015 Patel S, Cai X. Evolution of acidic Ca²⁺ stores and their resident Ca²⁺-permeable channels. Cell Calcium. 57: 222-30. PMID 25591931 DOI: 10.1016/j.ceca.2014.12.005  0.355
2015 Cai X, Wang X, Patel S, Clapham DE. Insights into the early evolution of animal calcium signaling machinery: a unicellular point of view. Cell Calcium. 57: 166-73. PMID 25498309 DOI: 10.1016/j.ceca.2014.11.007  0.355
2015 Chow A, Cai X, Hu S, Wang X. Iodine Deficiency–Induced Goiter in Central New Jersey: A Case Series Aace Clinical Case Reports. 1: e40-e44. DOI: 10.4158/EP14340.CR  0.18
2014 Rahman T, Cai X, Brailoiu GC, Abood ME, Brailoiu E, Patel S. Two-pore channels provide insight into the evolution of voltage-gated Ca2+ and Na+ channels. Science Signaling. 7: ra109. PMID 25406377 DOI: 10.1126/scisignal.2005450  0.33
2014 Cai X, Wang X, Clapham DE. Early evolution of the eukaryotic Ca2+ signaling machinery: conservation of the CatSper channel complex. Molecular Biology and Evolution. 31: 2735-40. PMID 25063443 DOI: 10.1093/molbev/msu218  0.351
2014 Cai X, Srivastava S, Surindran S, Li Z, Skolnik EY. Regulation of the epithelial Ca²⁺ channel TRPV5 by reversible histidine phosphorylation mediated by NDPK-B and PHPT1. Molecular Biology of the Cell. 25: 1244-50. PMID 24523290 DOI: 10.1091/mbc.E13-04-0180  0.691
2012 Srivastava S, Cai X, Li Z, Sun Y, Skolnik EY. Phosphatidylinositol-3-kinase C2β and TRIM27 function to positively and negatively regulate IgE receptor activation of mast cells. Molecular and Cellular Biology. 32: 3132-9. PMID 22645315 DOI: 10.1128/MCB.00019-12  0.704
2012 Cai X. Evolutionary genomics reveals the premetazoan origin of opposite gating polarity in animal-type voltage-gated ion channels Genomics. 99: 241-245. PMID 22326743 DOI: 10.1016/j.ygeno.2012.01.007  0.302
2012 Cai X. Ancient origin of four-domain voltage-gated Na + channels predates the divergence of animals and fungi Journal of Membrane Biology. 245: 117-123. PMID 22258316 DOI: 10.1007/s00232-012-9415-9  0.281
2012 Wu JH, Zhang L, Fanaroff AC, Cai X, Sharma KC, Brian L, Exum ST, Shenoy SK, Peppel K, Freedman NJ. G protein-coupled receptor kinase-5 attenuates atherosclerosis by regulating receptor tyrosine kinases and 7-transmembrane receptors. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 308-16. PMID 22095977 DOI: 10.1161/Atvbaha.111.239608  0.613
2012 Cai X. P2X receptor homologs in basal fungi. Purinergic Signalling. 8: 11-3. PMID 21887491 DOI: 10.1007/s11302-011-9261-8  0.245
2012 Cai X, Clapham DE. Ancestral Ca2+ signaling machinery in early animal and fungal evolution. Molecular Biology and Evolution. 29: 91-100. PMID 21680871 DOI: 10.1093/molbev/msr149  0.348
2011 Cai X, Srivastava S, Sun Y, Li Z, Wu H, Zuvela-Jelaska L, Li J, Salamon RS, Backer JM, Skolnik EY. Tripartite motif containing protein 27 negatively regulates CD4 T cells by ubiquitinating and inhibiting the class II PI3K-C2β. Proceedings of the National Academy of Sciences of the United States of America. 108: 20072-7. PMID 22128329 DOI: 10.1073/Pnas.1111233109  0.672
2010 Cai X, Patel S. Degeneration of an intracellular ion channel in the primate lineage by relaxation of selective constraints. Molecular Biology and Evolution. 27: 2352-9. PMID 20463046 DOI: 10.1093/molbev/msq122  0.328
2010 Brailoiu E, Hooper R, Cai X, Brailoiu GC, Keebler MV, Dun NJ, Marchant JS, Patel S. An ancestral deuterostome family of two-pore channels mediates nicotinic acid adenine dinucleotide phosphate-dependent calcium release from acidic organelles. The Journal of Biological Chemistry. 285: 2897-901. PMID 19940116 DOI: 10.1074/Jbc.C109.081943  0.262
2009 Brailoiu E, Churamani D, Cai X, Schrlau MG, Brailoiu GC, Gao X, Hooper R, Boulware MJ, Dun NJ, Marchant JS, Patel S. Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling. The Journal of Cell Biology. 186: 201-9. PMID 19620632 DOI: 10.1083/Jcb.200904073  0.277
2009 Cai X, Wu JH, Exum ST, Oppermann M, Premont RT, Shenoy SK, Freedman NJ. Reciprocal regulation of the platelet-derived growth factor receptor-beta and G protein-coupled receptor kinase 5 by cross-phosphorylation: effects on catalysis. Molecular Pharmacology. 75: 626-36. PMID 19092051 DOI: 10.1124/Mol.108.050278  0.623
2008 Cai X. A new tr(i)p to sense pain: TRPA1 channel as a target for novel analgesics Expert Review of Neurotherapeutics. 8: 1675-1681. PMID 18986238 DOI: 10.1586/14737175.8.11.1675  0.256
2008 Cai X, Clapham DE. Evolutionary genomics reveals lineage-specific gene loss and rapid evolution of a sperm-specific ion channel complex: CatSpers and CatSperbeta. Plos One. 3: e3569. PMID 18974790 DOI: 10.1371/journal.pone.0003569  0.295
2008 Cai X. Unicellular Ca2+ signaling 'toolkit' at the origin of metazoa Molecular Biology and Evolution. 25: 1357-1361. PMID 18385221 DOI: 10.1093/molbev/msn077  0.373
2008 Cai X. Subunit stoichiometry and channel pore structure of ion channels: All for one, or one for one? Journal of Physiology. 586: 925-926. PMID 18079155 DOI: 10.1113/jphysiol.2007.149153  0.239
2007 Cai X. Molecular Evolution and Functional Divergence of the Ca2+ Sensor Protein in Store-operated Ca2+ Entry: Stromal Interaction Molecule Plos One. 2. PMID 17622354 DOI: 10.1371/journal.pone.0000609  0.371
2007 Cai X. Molecular Evolution and Structural Analysis of the Ca2+ Release-Activated Ca2+ Channel Subunit, Orai Journal of Molecular Biology. 368: 1284-1291. PMID 17400243 DOI: 10.1016/j.jmb.2007.03.022  0.376
2006 Cai X, Freedman NJ. New therapeutic possibilities for vein graft disease in the post-edifoligide era. Future Cardiology. 2: 493-501. PMID 19804184 DOI: 10.2217/14796678.2.4.493  0.605
2006 Cai X. Regulation of smooth muscle cells in development and vascular disease: Current therapeutic strategies Expert Review of Cardiovascular Therapy. 4: 789-800. PMID 17173496 DOI: 10.1586/14779072.4.6.789  0.365
2006 Wu JH, Goswami R, Cai X, Exum ST, Huang X, Zhang L, Brian L, Premont RT, Peppel K, Freedman NJ. Regulation of the platelet-derived growth factor receptor-beta by G protein-coupled receptor kinase-5 in vascular smooth muscle cells involves the phosphatase Shp2. The Journal of Biological Chemistry. 281: 37758-72. PMID 17018529 DOI: 10.1074/Jbc.M605756200  0.647
2005 Cai X, Zhang Y. Molecular evolution of the ankyrin gene family. Molecular Biology and Evolution. 23: 550-8. PMID 16280541 DOI: 10.1093/molbev/msj056  0.273
2004 Cai X, Lytton J. The cation/Ca(2+) exchanger superfamily: phylogenetic analysis and structural implications. Molecular Biology and Evolution. 21: 1692-703. PMID 15163769 DOI: 10.1093/molbev/msh177  0.632
2004 Cai X, Lytton J. Molecular cloning of a sixth member of the K+-dependent Na+/Ca2+ exchanger gene family, NCKX6. The Journal of Biological Chemistry. 279: 5867-76. PMID 14625281 DOI: 10.1074/jbc.M310908200  0.645
2002 Cai X, Zhang K, Lytton J. Topological studies of the rat brain K+-dependent Na+/Ca2+ exchanger NCKX2. Annals of the New York Academy of Sciences. 976: 90-3. PMID 12502542 DOI: 10.1111/j.1749-6632.2002.tb04722.x  0.607
2002 Cai X, Zhang K, Lytton J. A novel topology and redox regulation of the rat brain K+-dependent Na+/Ca2+ exchanger, NCKX2. The Journal of Biological Chemistry. 277: 48923-30. PMID 12377762 DOI: 10.1074/jbc.M208818200  0.626
2001 Kraev A, Quednau BD, Leach S, Li XF, Dong H, Winkfein R, Perizzolo M, Cai X, Yang R, Philipson KD, Lytton J. Molecular cloning of a third member of the potassium-dependent sodium-calcium exchanger gene family, NCKX3. The Journal of Biological Chemistry. 276: 23161-72. PMID 11294880 DOI: 10.1074/JBC.M102314200  0.611
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