Arthur M. Brown - Publications

Affiliations: 
ChanTest, Garfield Heights, OH, United States 
Area:
Ion Channels
Website:
http://www.chantest.com/

117 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Kuryshev YA, Brown AM, Duzic E, Kirsch GE. Evaluating state dependence and subtype selectivity of calcium channel modulators in automated electrophysiology assays. Assay and Drug Development Technologies. 12: 110-9. PMID 24579774 DOI: 10.1089/adt.2013.552  0.52
2010 Kuryshev YA, Bruening-Wright A, Brown AM, Kirsch GE. Increased cardiac risk in concomitant methadone and diazepam treatment: pharmacodynamic interactions in cardiac ion channels. Journal of Cardiovascular Pharmacology. 56: 420-30. PMID 20930594 DOI: 10.1097/FJC.0b013e3181f1d21b  0.52
2010 Peng S, Lacerda AE, Kirsch GE, Brown AM, Bruening-Wright A. The action potential and comparative pharmacology of stem cell-derived human cardiomyocytes. Journal of Pharmacological and Toxicological Methods. 61: 277-86. PMID 20153443 DOI: 10.1016/j.vascn.2010.01.014  0.52
2009 Brimecombe JC, Kirsch GE, Brown AM. Test article concentrations in the hERG assay: losses through the perfusion, solubility and stability. Journal of Pharmacological and Toxicological Methods. 59: 29-34. PMID 19028590 DOI: 10.1016/j.vascn.2008.10.004  0.52
2008 Wible BA, Kuryshev YA, Smith SS, Liu Z, Brown AM. An ion channel library for drug discovery and safety screening on automated platforms. Assay and Drug Development Technologies. 6: 765-80. PMID 19090691 DOI: 10.1089/adt.2008.0171  0.48
2008 Lacerda AE, Kuryshev YA, Chen Y, Renganathan M, Eng H, Danthi SJ, Kramer JW, Yang T, Brown AM. Alfuzosin delays cardiac repolarization by a novel mechanism. The Journal of Pharmacology and Experimental Therapeutics. 324: 427-33. PMID 17986649 DOI: 10.1124/jpet.107.128405  0.52
2005 Brown AM. HERG block, QT liability and sudden cardiac death. Novartis Foundation Symposium. 266: 118-31; discussion 1. PMID 16050265  0.52
2005 Ficker E, Dennis A, Kuryshev Y, Wible BA, Brown AM. HERG channel trafficking. Novartis Foundation Symposium. 266: 57-69; discussion 70. PMID 16050262  0.52
2005 Wible BA, Hawryluk P, Ficker E, Kuryshev YA, Kirsch G, Brown AM. HERG-Lite: a novel comprehensive high-throughput screen for drug-induced hERG risk. Journal of Pharmacological and Toxicological Methods. 52: 136-45. PMID 15950494 DOI: 10.1016/j.vascn.2005.03.008  0.48
2005 Kuryshev YA, Ficker E, Wang L, Hawryluk P, Dennis AT, Wible BA, Brown AM, Kang J, Chen XL, Sawamura K, Reynolds W, Rampe D. Pentamidine-induced long QT syndrome and block of hERG trafficking. The Journal of Pharmacology and Experimental Therapeutics. 312: 316-23. PMID 15340016 DOI: 10.1124/jpet.104.073692  0.52
2005 Brown AM. HERG assay, QT liability, and sudden cardiac death Cardiac Safety of Noncardiac Drugs: Practical Guidelines For Clinical Research and Drug Development. 67-81. DOI: 10.1007/978-1-59259-884-7_4  0.52
2004 Kirsch GE, Trepakova ES, Brimecombe JC, Sidach SS, Erickson HD, Kochan MC, Shyjka LM, Lacerda AE, Brown AM. Variability in the measurement of hERG potassium channel inhibition: effects of temperature and stimulus pattern. Journal of Pharmacological and Toxicological Methods. 50: 93-101. PMID 15385083 DOI: 10.1016/j.vascn.2004.06.003  0.52
2004 Ficker E, Kuryshev YA, Dennis AT, Obejero-Paz C, Wang L, Hawryluk P, Wible BA, Brown AM. Mechanisms of arsenic-induced prolongation of cardiac repolarization. Molecular Pharmacology. 66: 33-44. PMID 15213294 DOI: 10.1124/mol.66.1.33  0.52
2004 Kaiser L, Davis JM, Schwartz KA, Brittenham GM, Yang T, Brown AM. Are there problems with the "time compressed model" of iron overload? Journal of Laboratory and Clinical Medicine. 143: 130-134. PMID 14966469 DOI: 10.1016/j.lab.2003.10.010  0.52
2003 Yang T, Brittenham GM, Dong WQ, Levy MN, Obejero-Paz CA, Kuryshev YA, Brown AM. Deferoxamine prevents cardiac hypertrophy and failure in the gerbil model of iron-induced cardiomyopathy. The Journal of Laboratory and Clinical Medicine. 142: 332-40. PMID 14647037 DOI: 10.1016/S0022-2143(03)00135-5  0.52
2003 Laurita KR, Chuck ET, Yang T, Dong WQ, Kuryshev YA, Brittenham GM, Rosenbaum DS, Brown AM. Optical mapping reveals conduction slowing and impulse block in iron-overload cardiomyopathy. The Journal of Laboratory and Clinical Medicine. 142: 83-9. PMID 12960954 DOI: 10.1016/S0022-2143(03)00060-X  0.52
2003 Kaiser L, Davis JM, Schwartz KA, Brittenham GM, Kuryshev YA, Obejero-Paz CA, Yang T, Dong WQ, Levy MN, Brown AM. Does the gerbil model mimic human iron overload? Journal of Laboratory and Clinical Medicine. 141: 419-422. PMID 12819640 DOI: 10.1016/S0022-2143(03)00038-6  0.52
2003 Ficker E, Dennis AT, Wang L, Brown AM. Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel HERG. Circulation Research. 92: e87-100. PMID 12775586 DOI: 10.1161/01.RES.0000079028.31393.15  0.52
2003 Obejero-Paz CA, Yang T, Dong WQ, Levy MN, Brittenham GM, Kuryshev YA, Brown AM. Deferoxamine promotes survival and prevents electrocardiographic abnormalities in the gerbil model of iron-overload cardiomyopathy. The Journal of Laboratory and Clinical Medicine. 141: 121-30. PMID 12577048 DOI: 10.1067/mlc.2003.18  0.52
2003 Wu KL, Khan S, Lakhe-Reddy S, Wang L, Jarad G, Miller RT, Konieczkowski M, Brown AM, Sedor JR, Schelling JR. Renal tubular epithelial cell apoptosis is associated with caspase cleavage of the NHE1 Na+/H+ exchanger. American Journal of Physiology. Renal Physiology. 284: F829-39. PMID 12453872 DOI: 10.1152/ajprenal.00314.2002  0.52
2002 Yang T, Dong WQ, Kuryshev YA, Obejero-Paz C, Levy MN, Brittenham GM, Kiatchoosakun S, Kirkpatrick D, Hoit BD, Brown AM. Bimodal cardiac dysfunction in an animal model of iron overload. The Journal of Laboratory and Clinical Medicine. 140: 263-71. PMID 12389025 DOI: 10.1067/mlc.2002.127725  0.52
2002 Wible BA, Wang L, Kuryshev YA, Basu A, Haldar S, Brown AM. Increased K+ efflux and apoptosis induced by the potassium channel modulatory protein KChAP/PIAS3beta in prostate cancer cells. The Journal of Biological Chemistry. 277: 17852-62. PMID 11877452 DOI: 10.1074/jbc.M201689200  0.52
2002 Benhorin J, Moss AJ, Bak M, Zareba W, Kaufman ES, Kerem B, Towbin JA, Priori S, Kass RS, Attali B, Brown AM, Ficker E. Variable expression of long QT syndrome among gene carriers from families with five different HERG mutations. Annals of Noninvasive Electrocardiology : the Official Journal of the International Society For Holter and Noninvasive Electrocardiology, Inc. 7: 40-6. PMID 11844290  0.52
2002 Ficker E, Obejero-Paz CA, Zhao S, Brown AM. The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations. The Journal of Biological Chemistry. 277: 4989-98. PMID 11741928 DOI: 10.1074/jbc.M107345200  0.52
2001 Ficker E, Jarolimek W, Brown AM. Molecular determinants of inactivation and dofetilide block in ether a-go-go (EAG) channels and EAG-related K(+) channels. Molecular Pharmacology. 60: 1343-8. PMID 11723241  0.52
2001 Kuryshev YA, Wible BA, Gudz TI, Ramirez AN, Brown AM. KChAP/Kvbeta1.2 interactions and their effects on cardiac Kv channel expression. American Journal of Physiology. Cell Physiology. 281: C290-9. PMID 11401852  0.52
2001 Kaufman ES, Priori SG, Napolitano C, Schwartz PJ, Iyengar S, Elston RC, Schnell AH, Gorodeski EZ, Rammohan G, Bahhur NO, Connuck D, Verrilli L, Rosenbaum DS, Brown AM. Electrocardiographic prediction of abnormal genotype in congenital long QT syndrome: experience in 101 related family members. Journal of Cardiovascular Electrophysiology. 12: 455-61. PMID 11332568 DOI: 10.1046/j.1540-8167.2001.00455.x  0.52
2001 Thomas D, Wendt-Nordahl G, Röckl K, Ficker E, Brown AM, Kiehn J. High-affinity blockade of human ether-a-go-go-related gene human cardiac potassium channels by the novel antiarrhythmic drug BRL-32872 Journal of Pharmacology and Experimental Therapeutics. 297: 753-761. PMID 11303067  0.52
2001 Peri R, Wible BA, Brown AM. Mutations in the Kv beta 2 binding site for NADPH and their effects on Kv1.4. The Journal of Biological Chemistry. 276: 738-41. PMID 11024060 DOI: 10.1074/jbc.M008445200  0.52
2001 Lacerda AE, Kramer J, Shen KZ, Thomas D, Brown AM. Comparison of block among cloned cardiac potassium channels by non-antiarrhythmic drugs European Heart Journal, Supplement. 3: K23-K30. DOI: 10.1016/S1520-765X(01)90003-3  0.52
2000 Ficker E, Dennis AT, Obejero-Paz CA, Castaldo P, Taglialatela M, Brown AM. Retention in the endoplasmic reticulum as a mechanism of dominant-negative current suppression in human long QT syndrome Journal of Molecular and Cellular Cardiology. 32: 2327-2337. PMID 11113008 DOI: 10.1006/jmcc.2000.1263  0.52
2000 Bianchi L, Priori SG, Napolitano C, Surewicz KA, Dennis AT, Memmi M, Schwartz PJ, Brown AM. Mechanisms of I(Ks) suppression in LQT1 mutants. American Journal of Physiology. Heart and Circulatory Physiology. 279: H3003-11. PMID 11087258  0.52
2000 Ficker E, Thomas D, Viswanathan PC, Dennis AT, Priori SG, Napolitano C, Memmi M, Wible BA, Kaufman ES, Iyengar S, Schwartz PJ, Rudy Y, Brown AM. Novel characteristics of a misprocessed mutant HERG channel linked to hereditary long QT syndrome. American Journal of Physiology. Heart and Circulatory Physiology. 279: H1748-56. PMID 11009462 DOI: 10.1152/ajpheart.2000.279.4.H1748  0.52
2000 Napolitano C, Schwartz PJ, Brown AM, Ronchetti E, Bianchi L, Pinnavaia A, Acquaro G, Priori SG. Evidence for a cardiac ion channel mutation underlying drug-induced QT prolongation and life-threatening arrhythmias. Journal of Cardiovascular Electrophysiology. 11: 691-6. PMID 10868744  0.52
2000 Kuryshev YA, Gudz TI, Brown AM, Wible BA. KChAP as a chaperone for specific K(+) channels. American Journal of Physiology. Cell Physiology. 278: C931-41. PMID 10794667  0.52
2000 Brown AM, Rampe D. Drug-induced long QT syndrome: Is HERG the root of all evil Pharmaceutical News. 7: 15-20.  0.52
1999 Thoren P, Munch PA, Brown AM. Mechanisms for activation of aortic baroreceptor C-fibres in rabbits and rats Acta Physiologica Scandinavica. 166: 167-174. PMID 10468652 DOI: 10.1046/j.1365-201x.1999.00556.x  0.52
1999 Pratt C, Brown AM, Rampe D, Mason J, Russell T, Reynolds R, Ahlbrandt R. Cardiovascular safety of fexofenadine HCl Clinical and Experimental Allergy, Supplement. 29: 212-216. PMID 10444240  0.52
1999 Kuryshev YA, Brittenham GM, Fujioka H, Kannan P, Shieh CC, Cohen SA, Brown AM. Decreased sodium and increased transient outward potassium currents in iron-loaded cardiac myocytes: Implications for the arrhythmogenesis of human siderotic heart disease Circulation. 100: 675-683. PMID 10441107  0.52
1999 Kiehn J, Lacerda AE, Brown AM. Pathways of HERG inactivation American Journal of Physiology - Heart and Circulatory Physiology. 277: H199-H210. PMID 10409198  0.52
1999 Bianchi L, Shen Z, Dennis AT, Priori SG, Napolitano C, Ronchetti E, Bryskin R, Schwartz PJ, Brown AM. Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome. Human Molecular Genetics. 8: 1499-507. PMID 10400998 DOI: 10.1093/hmg/8.8.1499  0.52
1999 Bianchi L, Priori SG, Shen Z, Dennis AT, Napolitano C, Ronchetti E, Bryskin R, Schwartz PJ, Brown AM. Corrigendum: Cellular dysfunction of LQT5-minK mutants: Abnormalities of IKs, IKr and trafficking in long QT syndrome (Human Molecular Genetics (1999) 8 (1499-1507)) Human Molecular Genetics. 8: 2335. DOI: 10.1093/hmg/8.12.2335  0.52
1998 Accili EA, Kuryshev YA, Wible BA, Brown AM. Separable effects of human Kvbeta1.2 N- and C-termini on inactivation and expression of human Kv1.4. The Journal of Physiology. 512: 325-36. PMID 9763623 DOI: 10.1111/j.1469-7793.1998.325be.x  0.52
1998 Kramer JW, Post MA, Brown AM, Kirsch GE. Modulation of potassium channel gating by coexpression of Kv2.1 with regulatory Kv5.1 or Kv6.1 alpha-subunits. The American Journal of Physiology. 274: C1501-10. PMID 9696692  0.52
1998 Dumaine R, Roy ML, Brown AM. Blockade of HERG and Kv1.5 by ketoconazole Journal of Pharmacology and Experimental Therapeutics. 286: 727-735. PMID 9694927  0.52
1998 Priori SG, Schwartz PJ, Napolitano C, Bianchi L, Dennis A, De Fusco M, Brown AM, Casari G. A recessive variant of the Romano-Ward long-QT syndrome? Circulation. 97: 2420-5. PMID 9641694  0.52
1998 Schwalbe RA, Bianchi L, Accili EA, Brown AM. Functional consequences of ROMK mutants linked to antenatal Bartter's syndrome and implications for treatment. Human Molecular Genetics. 7: 975-80. PMID 9580661 DOI: 10.1093/hmg/7.6.975  0.52
1998 Wible BA, Yang Q, Kuryshev YA, Accili EA, Brown AM. Cloning and expression of a novel K+ channel regulatory protein, KChAP. The Journal of Biological Chemistry. 273: 11745-51. PMID 9565597 DOI: 10.1074/jbc.273.19.11745  0.52
1998 Ficker E, Jarolimek W, Johann K, Baumann A, Brown AM. Molecular determinants of dofetilide block of HERG K+ channels Circulation Research. 82: 386-395. PMID 9486667  0.52
1997 Pascual JM, Shieh CC, Kirsch GE, Brown AM. Contribution of the NHterminus of Kv2.1 to channel activation. American Journal of Physiology. Cell Physiology. 273: C1849-C1858. PMID 29585075 DOI: 10.1152/ajpcell.1997.273.6.C1849  0.52
1997 Pascual JM, Shieh CC, Kirsch GE, Brown AM. Contribution of the NH2 terminus of Kv2.1 to channel activation American Journal of Physiology - Cell Physiology. 273: C1849-C1858. PMID 9435489  0.52
1997 Rampe D, Roy ML, Dennis A, Brown AM. A mechanism for the proarrhythmic effects of cisapride (Propulsid): High affinity blockade of the human cardiac potassium channel HERG Febs Letters. 417: 28-32. PMID 9395068 DOI: 10.1016/S0014-5793(97)01249-0  0.52
1997 Accili EA, Kiehn J, Wible BA, Brown AM. Interactions among inactivating and noninactivating Kvbeta subunits, and Kvalpha1.2, produce potassium currents with intermediate inactivation. The Journal of Biological Chemistry. 272: 28232-6. PMID 9353274 DOI: 10.1074/jbc.272.45.28232  0.52
1997 Accili EA, Kiehn J, Yang Q, Wang Z, Brown AM, Wible BA. Separable Kvbeta subunit domains alter expression and gating of potassium channels. The Journal of Biological Chemistry. 272: 25824-31. PMID 9325312 DOI: 10.1074/jbc.272.41.25824  0.52
1997 Schwalbe RA, Bianchi L, Brown AM. Mapping the kidney potassium channel ROMK1. Glycosylation of the pore signature sequence and the COOH terminus. The Journal of Biological Chemistry. 272: 25217-23. PMID 9312136 DOI: 10.1074/jbc.272.40.25217  0.52
1997 Brown AM. Cardiac potassium channels in health and disease Trends in Cardiovascular Medicine. 7: 118-124. DOI: 10.1016/S1050-1738(97)00002-9  0.52
1996 Taglialatela M, Ongini E, Brown AM, Di Renzo G, Annunziato L. Felbamate inhibits cloned voltage-dependent Na+ channels from human and rat brain European Journal of Pharmacology. 316: 373-377. PMID 8982710 DOI: 10.1016/S0014-2999(96)00802-3  0.52
1996 Post MA, Kirsch GE, Brown AM. Kv2.1 and electrically silent Kv6.1 potassium channel subunits combine and express a novel current Febs Letters. 399: 177-182. PMID 8980147 DOI: 10.1016/S0014-5793(96)01316-6  0.52
1996 Kiehn J, Lacerda AE, Wible B, Brown AM. Molecular physiology and pharmacology of HERG. Single-channel currents and block by dofetilide. Circulation. 94: 2572-9. PMID 8921803  0.52
1996 Wang Z, Kiehn J, Yang Q, Brown AM, Wible BA. Comparison of binding and block produced by alternatively spliced Kvbeta1 subunits. The Journal of Biological Chemistry. 271: 28311-7. PMID 8910452 DOI: 10.1074/jbc.271.45.28311  0.52
1996 Schwalbe RA, Wang Z, Bianchi L, Brown AM. Novel sites of N-glycosylation in ROMK1 reveal the putative pore-forming segment H5 as extracellular. The Journal of Biological Chemistry. 271: 24201-6. PMID 8798662 DOI: 10.1074/jbc.271.39.24201  0.52
1996 Roy ML, Dumaine R, Brown AM. HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine Circulation. 94: 817-823. PMID 8772706  0.52
1996 Kiehn J, Wible B, Lacerda AE, Brown AM. Mapping the block of a cloned human inward rectifier potassium channel by dofetilide. Molecular Pharmacology. 50: 380-7. PMID 8700146  0.52
1996 Priori SG, Napolitano C, Cantù F, Brown AM, Schwartz PJ. Differential response to Na+ channel blockade, beta-adrenergic stimulation, and rapid pacing in a cellular model mimicking the SCN5A and HERG defects present in the long-QT syndrome. Circulation Research. 78: 1009-15. PMID 8635231  0.52
1996 Bianchi L, Roy ML, Taglialatela M, Lundgren DW, Brown AM, Ficker E. Regulation by spermine of native inward rectifier K+ channels in RBL-1 cells. The Journal of Biological Chemistry. 271: 6114-21. PMID 8626398 DOI: 10.1074/jbc.271.11.6114  0.52
1996 Dumaine R, Wang Q, Keating MT, Hartmann HA, Schwartz PJ, Brown AM, Kirsch GE. Multiple mechanisms of Na+ channel--linked long-QT syndrome. Circulation Research. 78: 916-24. PMID 8620612  0.52
1996 Jarolimek W, Soman KV, Alam M, Brown AM. Structure-activity relationship of quaternary ammonium ions at the external tetraethylammonium binding site of cloned potassium channels Molecular Pharmacology. 49: 165-171. PMID 8569703  0.52
1996 Dumaine R, Hartmann HA, Leishman DJ, Brown AM, Galvan M. Actions of dolasetron and its major metabolite on guinea-pig papillary muscle fibres and the α-subunit of human heart sodium channels expressed in Xenopus oocytes Drug Development Research. 37: 223-230. DOI: 10.1002/(SICI)1098-2299(199604)37:4<223::AID-DDR4>3.0.CO;2-N  0.52
1996 Brown AM. Ion channel genes in the heart Cardiology in Review. 4: 80-85.  0.52
1995 Taglialatela M, Ficker E, Wible B, Brown AM. Pharmacological implications of inward rectifier K+ channels regulation by cytoplasmic polyamines. Pharmacological Research. 32: 335-44. PMID 8736484 DOI: 10.1016/S1043-6618(05)80038-6  0.52
1995 Taglialatela M, Brown AM. Structural motifs underlying voltage-dependent K+ channel function Kidney International. 48: 918-922. PMID 8569100  0.52
1995 Pascual JM, Shieh CC, Kirsch GE, Brown AM. Multiple residues specify external tetraethylammonium blockade in voltage- gated potassium channels Biophysical Journal. 69: 428-434. PMID 8527656  0.52
1995 Taglialatela M, Ficker E, Wible BA, Brown AM. C-terminus determinants for Mg2+ and polyamine block of the inward rectifier K+ channel IRK1. The Embo Journal. 14: 5532-41. PMID 8521810  0.52
1995 Schwartz PJ, Priori SG, Locati EH, Napolitano C, Cantù F, Towbin JA, Keating MT, Hammoude H, Brown AM, Chen LS. Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate. Implications for gene-specific therapy. Circulation. 92: 3381-6. PMID 8521555  0.52
1995 Wible BA, De Biasi M, Majumder K, Taglialatela M, Brown AM. Cloning and functional expression of an inwardly rectifying K+ channel from human atrium. Circulation Research. 76: 343-50. PMID 7859381  0.52
1995 Schwalbe RA, Wang Z, Wible BA, Brown AM. Potassium channel structure and function as reported by a single glycosylation sequon. The Journal of Biological Chemistry. 270: 15336-40. PMID 7797521 DOI: 10.1074/jbc.270.25.15336  0.52
1995 Pascual JM, Shieh CC, Kirsch GE, Brown AM. K+ pore structure revealed by reporter cysteines at inner and outer surfaces Neuron. 14: 1055-1063. PMID 7748553 DOI: 10.1016/0896-6273(95)90344-5  0.52
1995 Kiehn J, Wible B, Ficker E, Taglialatela M, Brown AM. Cloned human inward rectifier K+ channel as a target for class III methanesulfonanilides. Circulation Research. 77: 1151-5. PMID 7586228  0.52
1995 Soman KV, McCammon JA, Brown AM. Secondary structure prediction of the H5 pore of potassium channels Protein Engineering. 8: 397-401. PMID 7567925 DOI: 10.1093/protein/8.4.397  0.52
1995 Jarolimek W, Soman KV, Alam M, Brown AM. The selectivity of different external binding sites for quaternary ammonium ions in cloned potassium channels PflüGers Archiv European Journal of Physiology. 430: 672-681. PMID 7478918 DOI: 10.1007/BF00386161  0.52
1994 Taglialatela M, Champagne MS, Drewe JA, Brown AM. Comparison of H5, S6, and H5-S6 exchanges on pore properties of voltage-dependent K+ channels Journal of Biological Chemistry. 269: 13867-13873. PMID 8188663  0.52
1994 Taglialatela M, Wible BA, Caporaso R, Brown AM. Specification of pore properties by the carboxyl terminus of inwardly rectifying K+ channels. Science (New York, N.Y.). 264: 844-7. PMID 8171340  0.52
1994 Taglialatela M, Payne JP, Drewe JA, Brown AM. Rescue of lethal subunits into functional K+ channels Biophysical Journal. 66: 179-190. PMID 8130337  0.52
1994 Wible BA, Taglialatela M, Ficker E, Brown AM. Gating of inwardly rectifying K+ channels localized to a single negatively charged residue. Nature. 371: 246-9. PMID 8078584 DOI: 10.1038/371246a0  0.52
1994 Lacerda AE, Perez-Reyes E, Wei X, Castellano A, Brown AM. T-type and N-type calcium channels of Xenopus oocytes: evidence for specific interactions with beta subunits. Biophysical Journal. 66: 1833-43. PMID 8075321 DOI: 10.1016/S0006-3495(94)80977-4  0.52
1994 Hartmann HA, Tiedeman AA, Chen SF, Brown AM, Kirsch GE. Effects of III-IV linker mutations on human heart Na+ channel inactivation gating. Circulation Research. 75: 114-22. PMID 8013069  0.52
1994 Ficker E, Taglialatela M, Wible BA, Henley CM, Brown AM. Spermine and spermidine as gating molecules for inward rectifier K+ channels. Science (New York, N.Y.). 266: 1068-72. PMID 7973666  0.52
1994 Brown AM, Schwindt PC, Crill WE. Different voltage dependence of transient and persistent Na+ currents is compatible with modal-gating hypothesis for sodium channels. Journal of Neurophysiology. 71: 2562-5. PMID 7931536  0.52
1994 Brown AM. The pore of voltage-dependent potassium channels Renal Physiology and Biochemistry. 17: 178-181. PMID 7518952 DOI: 10.1159/000173812  0.52
1994 Brown AM, Sayer RJ, Schwindt PC, Crill WE. P-type calcium channels in rat neocortical neurones. The Journal of Physiology. 475: 197-205. PMID 7517449  0.52
1994 Wible BA, Brown AM. Function and structure of voltage-dependent potassium channels Drug Development Research. 33: 225-234. DOI: 10.1002/ddr.430330306  0.52
1993 Brown AM, Drewe JA, Hartmann HA, Taglialatela M, De Biasi M, Soman K, Kirsch GE. The potassium pore and its regulation. Annals of the New York Academy of Sciences. 707: 74-80. PMID 9137543  0.52
1993 Fedida D, Wible B, Wang Z, Fermini B, Faust F, Nattel S, Brown AM. Identity of a novel delayed rectifier current from human heart with a cloned K+ channel current. Circulation Research. 73: 210-6. PMID 8508531  0.52
1993 De Biasi M, Hartmann HA, Drewe JA, Taglialatela M, Brown AM, Kirsch GE. Inactivation determined by a single site in K+ pores. PflüGers Archiv : European Journal of Physiology. 422: 354-63. PMID 8437886 DOI: 10.1007/BF00374291  0.52
1993 Critz SD, Wible BA, Lopez HS, Brown AM. Stable expression and regulation of a rat brain K+ channel. Journal of Neurochemistry. 60: 1175-8. PMID 8436968  0.52
1993 Rampe D, Wible B, Fedida D, Dage RC, Brown AM. Verapamil blocks a rapidly activating delayed rectifier K+ channel cloned from human heart. Molecular Pharmacology. 44: 642-8. PMID 8371716  0.52
1993 Brown AM. Functional bases for interpreting amino acid sequences of voltage-dependent K+ channels Annual Review of Biophysics and Biomolecular Structure. 22: 173-198. PMID 8347988  0.52
1993 Taglialatela M, Drewe JA, Brown AM. Barium blockade of a clonal potassium channel and its regulation by a critical pore residue Molecular Pharmacology. 44: 180-190. PMID 8341271  0.52
1993 Kirsch GE, Drewe JA, De Biasi M, Hartmann HA, Brown AM. Functional interactions between K+ pore residues located in different subunits. The Journal of Biological Chemistry. 268: 13799-804. PMID 8314749  0.52
1993 Rampe D, Wible B, Brown AM, Dage RC. Effects of terfenadine and its metabolites on a delayed rectifier K+ channel cloned from human heart. Molecular Pharmacology. 44: 1240-5. PMID 8264561  0.52
1993 Morganroth J, Brown AM, Critz S, Crumb WJ, Kunze DL, Lacerda AE, Lopez H. Variability of the QTc interval: impact on defining drug effect and low-frequency cardiac event. The American Journal of Cardiology. 72: 26B-31B. PMID 8256752 DOI: 10.1016/0002-9149(93)90037-D  0.52
1993 De Biasi M, Drewe JA, Kirsch GE, Brown AM. Histidine substitution identifies a surface position and confers Cs+ selectivity on a K+ pore. Biophysical Journal. 65: 1235-42. PMID 8241404 DOI: 10.1016/S0006-3495(93)81154-8  0.52
1993 Taglialatela M, Drewe JA, Kirsch GE, De Biasi M, Hartmann HA, Brown AM. Regulation of K+/Rb+ selectivity and internal TEA blockade by mutations at a single site in K+ pores. PflüGers Archiv : European Journal of Physiology. 423: 104-12. PMID 7683786 DOI: 10.1007/BF00374967  0.52
1993 Brown AM. Membrane-delimited cell signaling complexes: Direct ion channel regulation by G Proteins The Journal of Membrane Biology. 131: 93-104. PMID 7680074 DOI: 10.1007/BF02791318  0.52
1993 Brown AM, Schwindt PC, Crill WE. Voltage dependence and activation kinetics of pharmacologically defined components of the high-threshold calcium current in rat neocortical neurons. Journal of Neurophysiology. 70: 1530-43. PMID 7506757  0.52
1992 Kirsch GE, Drewe JA, Hartmann HA, Taglialatela M, de Biasi M, Brown AM, Joho RH. Differences between the deep pores of K+ channels determined by an interacting pair of nonpolar amino acids. Neuron. 8: 499-505. PMID 1550675 DOI: 10.1016/0896-6273(92)90278-L  0.52
1983 Thoren P, Andresen MC, Brown AM. Resetting of aortic baroreceptors with non-myelinated afferent fibers in spontaneously hypertensive rats. Acta Physiologica Scandinavica. 117: 91-7. PMID 6858708 DOI: 10.1111/j.1748-1716.1983.tb07182.x  1
1983 Munch PA, Andresen MC, Brown AM. Rapid resetting of aortic baroreceptors in vitro. The American Journal of Physiology. 244: H672-80. PMID 6846555  1
1982 Thoren P, Andresen MC, Brown AM. Effects of changes in extracellular ionic concentrations on aortic baroreceptors with nonmyelinated afferent fibers. Circulation Research. 50: 413-8. PMID 7060235  1
1982 Andresen MC, Brown AM. Cellular basis of the photoresponse of an extraretinal photoreceptor. Experientia. 38: 1001-6. PMID 6290258  1
1980 Andresen MC, Brown AM. Baroreceptor function in spontaneously hypertensive rats. Effect of preventing hypertension. Circulation Research. 47: 829-34. PMID 7438333  1
1980 Andresen MC, Kuraoka S, Brown AM. Baroreceptor function and changes in strain sensitivity in normotensive and spontaneously hypertensive rats. Circulation Research. 47: 821-8. PMID 7438332  1
1979 Andresen MC, Kuraoka S, Brown AM. Individual and combined actions of calcium, sodium, and potassium ions on baroreceptors in the rat. Circulation Research. 45: 757-63. PMID 498439  1
1979 Krauhs JM, Andresen MC, Baur PS, Brown AM. Ultrastructure of Aplysia neurons having different degrees of light sensitivity. Journal of Neurobiology. 10: 455-64. PMID 490156 DOI: 10.1002/neu.480100504  1
1979 Andresen MC, Brown AM, Yasui S. The role of diffusion in the photoresponse of an extraretinal photoreceptor of Aplysia. The Journal of Physiology. 287: 283-301. PMID 430409  1
1979 Andresen MC, Brown AM. Photoresponses of a sensitive extraretinal photoreceptor in Aplysia. The Journal of Physiology. 287: 267-82. PMID 430406  1
1978 Andresen MC, Krauhs JM, Brown AM. Relationship of aortic wall and baroreceptor properties during development in normotensive and spontaneously hypertensive rats. Circulation Research. 43: 728-38. PMID 709739  1
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