| Year |
Citation |
Score |
| 2023 |
Yao Y, Fong Ng J, Park WD, Samur MK, Morelli E, Encinas J, Chyra Z, Xu Y, Derebail S, Epstein CB, Nabet B, Chesi M, Gray NS, Young R, Kwiatkowski N, ... ... Lin CY, et al. CDK7 controls E2F- and MYC-driven proliferative and metabolic vulnerabilities in multiple myeloma. Blood. PMID 36877894 DOI: 10.1182/blood.2022018885 |
0.516 |
|
| 2022 |
Morelli E, Fulciniti M, Samur MK, Ribeiro C, Wert-Lamas L, Henninger JE, Gulla A, Aktas Samur A, Todoerti K, Talluri S, Park WD, Federico C, Scionti F, Amodio N, Bianchi G, ... ... Lin CY, et al. A MIR17HG-derived Long Noncoding RNA Provides an Essential Chromatin Scaffold for Protein Interaction and Myeloma Growth. Blood. PMID 36126301 DOI: 10.1182/blood.2022016892 |
0.52 |
|
| 2022 |
Hsu A, Duan Q, Day DS, Luo X, McMahon S, Huang Y, Feldman ZB, Jiang Z, Zhang T, Liang Y, Alexanian M, Padmanabhan A, Brown JD, Lin CY, Gray NS, et al. Targeting transcription in heart failure via CDK7/12/13 inhibition. Nature Communications. 13: 4345. PMID 35896549 DOI: 10.1038/s41467-022-31541-8 |
0.484 |
|
| 2022 |
Eagle K, Harada T, Kalfon J, Perez MW, Heshmati Y, Ewers J, Vrabic Koren J, Dempster JM, Kugener G, Paralkar VR, Lin CY, Dharia NV, Stegmaier K, Orkin SH, Pimkin M. Transcriptional plasticity drives leukemia immune escape. Blood Cancer Discovery. PMID 35709529 DOI: 10.1158/2643-3230.BCD-21-0207 |
0.303 |
|
| 2022 |
Harada T, Heshmati Y, Kalfon J, Perez MW, Xavier Ferrucio J, Ewers J, Hubbell Engler B, Kossenkov A, Ellegast JM, Yi JS, Bowker A, Zhu Q, Eagle K, Liu T, Kai Y, ... ... Lin CY, et al. A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia. Genes & Development. 36: 368-389. PMID 35301220 DOI: 10.1101/gad.349284.121 |
0.425 |
|
| 2022 |
Eagle K, Jiang Y, Shi X, Li M, Obholzer NP, Hu T, Perez MW, Koren JV, Kitano A, Yi JS, Lin CY, Nakada D. An oncogenic enhancer encodes selective selenium dependency in AML. Cell Stem Cell. PMID 35108519 DOI: 10.1016/j.stem.2022.01.003 |
0.317 |
|
| 2021 |
Arabzade A, Zhao Y, Varadharajan S, Chen HC, Jessa S, Rivas B, Stuckert AJ, Solis M, Kardian A, Tlais D, Golbourn BJ, Stanton AJ, Chan YS, Olson C, Karlin KL, ... ... Lin CY, et al. ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma. Cancer Discovery. PMID 33741710 DOI: 10.1158/2159-8290.CD-20-1066 |
0.416 |
|
| 2021 |
Sheppard HE, Dall'Agnese A, Park WD, Shamim MH, Dubrulle J, Johnson HL, Stossi F, Cogswell P, Sommer J, Levy J, Sharifnia T, Wawer MJ, Nabet B, Gray NS, Clemons PA, ... ... Lin CY, et al. Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity. Cell Reports. Medicine. 2: 100188. PMID 33521702 DOI: 10.1016/j.xcrm.2020.100188 |
0.566 |
|
| 2020 |
Poon E, Liang T, Jamin Y, Walz S, Kwok C, Hakkert A, Barker K, Urban Z, Thway K, Zeid R, Hallsworth A, Box G, Ebus ME, Licciardello MP, Sbirkov Y, ... ... Lin CY, et al. Orally bioavailable CDK9/2 inhibitor shows mechanism-based therapeutic potential in MYCN-driven neuroblastoma. The Journal of Clinical Investigation. PMID 33016930 DOI: 10.1172/JCI134132 |
0.371 |
|
| 2019 |
Mercado N, Schutzius G, Kolter C, Estoppey D, Bergling S, Roma G, Gubser Keller C, Nigsch F, Salathe A, Terranova R, Reece-Hoyes J, Alford J, Russ C, Knehr J, Hoepfner D, ... ... Lin CY, et al. IRF2 is a master regulator of human keratinocyte stem cell fate. Nature Communications. 10: 4676. PMID 31611556 DOI: 10.1038/S41467-019-12559-X |
0.386 |
|
| 2019 |
Bleu M, Gaulis S, Lopes R, Sprouffske K, Apfel V, Holwerda S, Pregnolato M, Yildiz U, Cordoʹ V, Dost AFM, Knehr J, Carbone W, Lohmann F, Lin CY, Bradner JE, et al. PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma. Nature Communications. 10: 3739. PMID 31431624 DOI: 10.1038/S41467-019-11672-1 |
0.395 |
|
| 2019 |
Bassir SH, Garakani S, Wilk K, Aldawood ZA, Hou J, Yeh SA, Sfeir C, Lin CP, Intini G. Prx1 Expressing Cells Are Required for Periodontal Regeneration of the Mouse Incisor. Frontiers in Physiology. 10: 591. PMID 31231227 DOI: 10.3389/Fphys.2019.00591 |
0.318 |
|
| 2019 |
Mack SC, Singh I, Wang X, Hirsch R, Wu Q, Villagomez R, Bernatchez JA, Zhu Z, Gimple RC, Kim LJY, Morton A, Lai S, Qiu Z, Prager BC, Bertrand KC, ... ... Lin CY, et al. Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma. The Journal of Experimental Medicine. PMID 30948495 DOI: 10.1084/jem.20190196 |
0.471 |
|
| 2019 |
Olson CM, Liang Y, Leggett A, Park WD, Li L, Mills CE, Elsarrag SZ, Ficarro SB, Zhang T, Düster R, Geyer M, Sim T, Marto JA, Sorger PK, Westover KD, ... Lin CY, et al. Development of a Selective CDK7 Covalent Inhibitor Reveals Predominant Cell-Cycle Phenotype. Cell Chemical Biology. PMID 30905681 DOI: 10.1016/J.Chembiol.2019.02.012 |
0.348 |
|
| 2019 |
Struntz NB, Chen A, Deutzmann A, Wilson RM, Stefan E, Evans HL, Ramirez MA, Liang T, Caballero F, Wildschut MHE, Neel DV, Freeman DB, Pop MS, McConkey M, Muller S, ... ... Lin CY, et al. Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription. Cell Chemical Biology. PMID 30880155 DOI: 10.1016/J.Chembiol.2019.02.009 |
0.634 |
|
| 2019 |
Sharifnia T, Wawer MJ, Chen T, Huang QY, Weir BA, Sizemore A, Lawlor MA, Goodale A, Cowley GS, Vazquez F, Ott CJ, Francis JM, Sassi S, Cogswell P, Sheppard HE, ... ... Lin CY, et al. Small-molecule targeting of brachyury transcription factor addiction in chordoma. Nature Medicine. PMID 30664779 DOI: 10.1038/S41591-018-0312-3 |
0.414 |
|
| 2018 |
Fulciniti M, Lin CY, Samur MK, Lopez MA, Singh I, Lawlor MA, Szalat RE, Ott CJ, Avet-Loiseau H, Anderson KC, Young RA, Bradner JE, Munshi NC. Non-overlapping Control of Transcriptome by Promoter- and Super-Enhancer-Associated Dependencies in Multiple Myeloma. Cell Reports. 25: 3693-3705.e6. PMID 30590042 DOI: 10.1016/j.celrep.2018.12.016 |
0.62 |
|
| 2018 |
Mowery CT, Reyes JM, Cabal-Hierro L, Higby KJ, Karlin KL, Wang JH, Kimmerling RJ, Cejas P, Lim K, Li H, Furusawa T, Long HW, Pellman D, Chapuy B, Bustin M, ... ... Lin CY, et al. Trisomy of a Down Syndrome Critical Region Globally Amplifies Transcription via HMGN1 Overexpression. Cell Reports. 25: 1898-1911.e5. PMID 30428356 DOI: 10.1016/J.Celrep.2018.10.061 |
0.348 |
|
| 2018 |
Garancher A, Lin CY, Morabito M, Richer W, Rocques N, Larcher M, Bihannic L, Smith K, Miquel C, Leboucher S, Herath NI, Dupuy F, Varlet P, Haberler C, Walczak C, et al. NRL and CRX Define Photoreceptor Identity and Reveal Subgroup-Specific Dependencies in Medulloblastoma. Cancer Cell. 33: 435-449.e6. PMID 29533784 DOI: 10.1016/J.Ccell.2018.02.006 |
0.363 |
|
| 2018 |
Brown JD, Feldman ZB, Doherty SP, Reyes JM, Rahl PB, Lin CY, Sheng Q, Duan Q, Federation AJ, Kung AL, Haldar SM, Young RA, Plutzky J, Bradner JE. BET bromodomain proteins regulate enhancer function during adipogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29444854 DOI: 10.1073/Pnas.1711155115 |
0.562 |
|
| 2018 |
Zeid R, Lawlor MA, Poon E, Reyes JM, Fulciniti M, Lopez MA, Scott TG, Nabet B, Erb MA, Winter GE, Jacobson Z, Polaski DR, Karlin KL, Hirsch RA, Munshi NP, ... ... Lin CY, et al. Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma. Nature Genetics. PMID 29379199 DOI: 10.1038/S41588-018-0044-9 |
0.427 |
|
| 2017 |
Winter GE, Mayer A, Buckley DL, Erb MA, Roderick JE, Vittori S, Reyes JM, di Iulio J, Souza A, Ott CJ, Roberts JM, Zeid R, Scott TG, Paulk J, Lachance K, ... ... Lin CY, et al. BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment. Molecular Cell. PMID 28673542 DOI: 10.1016/J.Molcel.2017.06.004 |
0.431 |
|
| 2017 |
Liu Y, Chen S, Wang S, Soares F, Fischer M, Meng F, Du Z, Lin C, Meyer C, DeCaprio JA, Brown M, Liu XS, He HH. Transcriptional landscape of the human cell cycle. Proceedings of the National Academy of Sciences of the United States of America. PMID 28289232 DOI: 10.1073/Pnas.1617636114 |
0.439 |
|
| 2017 |
Dreijerink KM, Groner AC, Vos ES, Font-Tello A, Gu L, Chi D, Reyes J, Cook J, Lim E, Lin CY, de Laat W, Rao PK, Long HW, Brown M. Enhancer-Mediated Oncogenic Function of the Menin Tumor Suppressor in Breast Cancer. Cell Reports. 18: 2359-2372. PMID 28273452 DOI: 10.1016/J.Celrep.2017.02.025 |
0.38 |
|
| 2016 |
Silberstein L, Goncalves KA, Kharchenko PV, Turcotte R, Kfoury Y, Mercier F, Baryawno N, Severe N, Bachand J, Spencer JA, Papazian A, Lee D, Chitteti BR, Srour EF, Hoggatt J, ... ... Lin CP, et al. Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators. Cell Stem Cell. PMID 27524439 DOI: 10.1016/J.Stem.2016.07.004 |
0.346 |
|
| 2016 |
Spangle JM, Dreijerink KM, Groner AC, Cheng H, Ohlson CE, Reyes J, Lin CY, Bradner J, Zhao JJ, Roberts TM, Brown M. PI3K/AKT Signaling Regulates H3K4 Methylation in Breast Cancer. Cell Reports. PMID 27292631 DOI: 10.1016/J.Celrep.2016.05.046 |
0.308 |
|
| 2016 |
Saint-André V, Federation AJ, Lin CY, Abraham BJ, Reddy J, Lee TI, Bradner JE, Young RA. Models of human core transcriptional regulatory circuitries. Genome Research. PMID 26843070 DOI: 10.1101/Gr.197590.115 |
0.757 |
|
| 2016 |
Lin CY, Erkek S, Tong Y, Yin L, Federation AJ, Zapatka M, Haldipur P, Kawauchi D, Risch T, Warnatz HJ, Worst BC, Ju B, Orr BA, Zeid R, Polaski DR, et al. Active medulloblastoma enhancers reveal subgroup-specific cellular origins. Nature. PMID 26814967 DOI: 10.1038/Nature16546 |
0.31 |
|
| 2016 |
Heyn H, Vidal E, Ferreira HJ, Vizoso M, Sayols S, Gomez A, Moran S, Boque-Sastre R, Guil S, Martinez-Cardus A, Lin CY, Royo R, Sanchez-Mut JV, Martinez R, Gut M, et al. Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer. Genome Biology. 17: 11. PMID 26813288 DOI: 10.1186/S13059-016-0879-2 |
0.417 |
|
| 2016 |
Shu S, Lin CY, He HH, Witwicki RM, Tabassum DP, Roberts JM, Janiszewska M, Jin Huh S, Liang Y, Ryan J, Doherty E, Mohammed H, Guo H, Stover DG, Ekram MB, et al. Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer. Nature. PMID 26735014 DOI: 10.1038/Nature16508 |
0.433 |
|
| 2015 |
Nabet B, Ó Broin P, Reyes JM, Shieh K, Lin CY, Will CM, Popovic R, Ezponda T, Bradner JE, Golden AA, Licht JD. Deregulation of the Ras-Erk Signaling Axis Modulates the Enhancer Landscape. Cell Reports. 12: 1300-13. PMID 26279576 DOI: 10.1016/J.Celrep.2015.06.078 |
0.321 |
|
| 2015 |
Hnisz D, Schuijers J, Lin CY, Weintraub AS, Abraham BJ, Lee TI, Bradner JE, Young RA. Convergence of developmental and oncogenic signaling pathways at transcriptional super-enhancers. Molecular Cell. 58: 362-70. PMID 25801169 DOI: 10.1016/j.molcel.2015.02.014 |
0.559 |
|
| 2014 |
Zuo Z, Che X, Wang Y, Li B, Li J, Dai W, Lin CP, Huang C. High mobility group Box-1 inhibits cancer cell motility and metastasis by suppressing activation of transcription factor CREB and nWASP expression. Oncotarget. 5: 7458-70. PMID 25277185 DOI: 10.18632/Oncotarget.2150 |
0.305 |
|
| 2014 |
Ramsey H, Zhang Q, Brown DE, Steensma DP, Lin CP, Wu MX. Stress-induced hematopoietic failure in the absence of immediate early response gene X-1 (IEX-1, IER3). Haematologica. 99: 282-91. PMID 24056813 DOI: 10.3324/Haematol.2013.092452 |
0.333 |
|
| 2013 |
Chapuy B, McKeown MR, Lin CY, Monti S, Roemer MG, Qi J, Rahl PB, Sun HH, Yeda KT, Doench JG, Reichert E, Kung AL, Rodig SJ, Young RA, Shipp MA, et al. Discovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma. Cancer Cell. 24: 777-90. PMID 24332044 DOI: 10.1016/J.Ccr.2013.11.003 |
0.482 |
|
| 2013 |
Anand P, Brown JD, Lin CY, Qi J, Zhang R, Artero PC, Alaiti MA, Bullard J, Alazem K, Margulies KB, Cappola TP, Lemieux M, Plutzky J, Bradner JE, Haldar SM. BET bromodomains mediate transcriptional pause release in heart failure Cell. 154: 569-582. PMID 23911322 DOI: 10.1016/J.Cell.2013.07.013 |
0.303 |
|
| 2013 |
Ji X, Zhou Y, Pandit S, Huang J, Li H, Lin CY, Xiao R, Burge CB, Fu XD. SR proteins collaborate with 7SK and promoter-associated nascent RNA to release paused polymerase. Cell. 153: 855-68. PMID 23663783 DOI: 10.1016/J.Cell.2013.04.028 |
0.337 |
|
| 2013 |
Lovén J, Hoke HA, Lin CY, Lau A, Orlando DA, Vakoc CR, Bradner JE, Lee TI, Young RA. Selective inhibition of tumor oncogenes by disruption of super-enhancers. Cell. 153: 320-34. PMID 23582323 DOI: 10.1016/J.Cell.2013.03.036 |
0.702 |
|
| 2013 |
Whyte WA, Orlando DA, Hnisz D, Abraham BJ, Lin CY, Kagey MH, Rahl PB, Lee TI, Young RA. Master transcription factors and mediator establish super-enhancers at key cell identity genes. Cell. 153: 307-19. PMID 23582322 DOI: 10.1016/J.Cell.2013.03.035 |
0.627 |
|
| 2013 |
Sigova AA, Mullen AC, Molinie B, Gupta S, Orlando DA, Guenther MG, Almada AE, Lin C, Sharp PA, Giallourakis CC, Young RA. Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 2876-81. PMID 23382218 DOI: 10.1073/Pnas.1221904110 |
0.659 |
|
| 2012 |
Lovén J, Orlando DA, Sigova AA, Lin CY, Rahl PB, Burge CB, Levens DL, Lee TI, Young RA. Revisiting global gene expression analysis. Cell. 151: 476-82. PMID 23101621 DOI: 10.1016/J.Cell.2012.10.012 |
0.739 |
|
| 2012 |
Lin CY, Lovén J, Rahl PB, Paranal RM, Burge CB, Bradner JE, Lee TI, Young RA. Transcriptional amplification in tumor cells with elevated c-Myc. Cell. 151: 56-67. PMID 23021215 DOI: 10.1016/J.Cell.2012.08.026 |
0.611 |
|
| 2012 |
Azab AK, Hu J, Quang P, Azab F, Pitsillides C, Awwad R, Thompson B, Maiso P, Sun JD, Hart CP, Roccaro AM, Sacco A, Ngo HT, Lin CP, Kung AL, et al. Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features. Blood. 119: 5782-94. PMID 22394600 DOI: 10.1182/Blood-2011-09-380410 |
0.308 |
|
| 2011 |
White RM, Cech J, Ratanasirintrawoot S, Lin CY, Rahl PB, Burke CJ, Langdon E, Tomlinson ML, Mosher J, Kaufman C, Chen F, Long HK, Kramer M, Datta S, Neuberg D, et al. DHODH modulates transcriptional elongation in the neural crest and melanoma. Nature. 471: 518-22. PMID 21430780 DOI: 10.1038/Nature09882 |
0.483 |
|
| 2010 |
Rahl PB, Lin CY, Seila AC, Flynn RA, McCuine S, Burge CB, Sharp PA, Young RA. c-Myc regulates transcriptional pause release. Cell. 141: 432-45. PMID 20434984 DOI: 10.1016/J.Cell.2010.03.030 |
0.556 |
|
| 2010 |
Raaijmakers MH, Mukherjee S, Guo S, Zhang S, Kobayashi T, Schoonmaker JA, Ebert BL, Al-Shahrour F, Hasserjian RP, Scadden EO, Aung Z, Matza M, Merkenschlager M, Lin C, Rommens JM, et al. Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia. Nature. 464: 852-7. PMID 20305640 DOI: 10.1038/Nature08851 |
0.3 |
|
| 2008 |
Orlando DA, Lin CY, Bernard A, Wang JY, Socolar JE, Iversen ES, Hartemink AJ, Haase SB. Global control of cell-cycle transcription by coupled CDK and network oscillators. Nature. 453: 944-7. PMID 18463633 DOI: 10.1038/Nature06955 |
0.436 |
|
| 2004 |
Yang H, Ma G, Lin CH, Orr M, Wathelet MG. Mechanism for transcriptional synergy between interferon regulatory factor (IRF)-3 and IRF-7 in activation of the interferon-beta gene promoter. European Journal of Biochemistry. 271: 3693-703. PMID 15355347 DOI: 10.1111/j.1432-1033.2004.04310.x |
0.314 |
|
| 2003 |
Yang H, Lin CH, Ma G, Baffi MO, Wathelet MG. Interferon regulatory factor-7 synergizes with other transcription factors through multiple interactions with p300/CBP coactivators. The Journal of Biological Chemistry. 278: 15495-504. PMID 12604599 DOI: 10.1074/Jbc.M212940200 |
0.309 |
|
| Show low-probability matches. |