Kevin C. Ess, M.D./Ph.D - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
mTOR

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Neal EH, Marinelli NA, Shi Y, McClatchey PM, Balotin KM, Gullett DR, Hagerla KA, Bowman AB, Ess KC, Wikswo JP, Lippmann ES. A Simplified, Fully Defined Differentiation Scheme for Producing Blood-Brain Barrier Endothelial Cells from Human iPSCs. Stem Cell Reports. 12: 1380-1388. PMID 31189096 DOI: 10.1016/j.stemcr.2019.05.008  0.32
2019 Short B, Kozek L, Harmsen H, Zhang B, Wong M, Ess KC, Fu C, Naftel R, Pearson MM, Carson RP. Cerebral aquaporin-4 expression is independent of seizures in tuberous sclerosis complex. Neurobiology of Disease. PMID 31078684 DOI: 10.1016/j.nbd.2019.05.003  0.48
2017 Grier MD, West KL, Kelm ND, Fu C, Does MD, Parker B, McBrier E, Lagrange AH, Ess KC, Carson RP. Loss of mTORC2 signaling in oligodendrocyte precursor cells delays myelination. Plos One. 12: e0188417. PMID 29161318 DOI: 10.1371/journal.pone.0188417  0.48
2017 Armstrong LC, Westlake G, Snow JP, Cawthon B, Armour E, Bowman AB, Ess KC. "Heterozygous loss of TSC2 alters p53 signaling and human stem cell reprogramming". Human Molecular Genetics. PMID 28973543 DOI: 10.1093/hmg/ddx345  0.32
2016 West KL, Kelm ND, Carson RP, Gochberg DF, Ess KC, Does MD. Myelin Volume Fraction Imaging with MRI. Neuroimage. PMID 28025129 DOI: 10.1016/j.neuroimage.2016.12.067  0.48
2016 Sahin M, Henske EP, Manning BD, Ess KC, Bissler JJ, Klann E, Kwiatkowski DJ, Roberds SL, Silva AJ, Hillaire-Clarke CS, Young LR, Zervas M, Mamounas LA. Advances and Future Directions for Tuberous Sclerosis Complex Research: Recommendations From the 2015 Strategic Planning Conference. Pediatric Neurology. PMID 27267556 DOI: 10.1016/j.pediatrneurol.2016.03.015  0.48
2016 Tidball AM, Neely MD, Chamberlin R, Aboud AA, Kumar KK, Han B, Bryan MR, Aschner M, Ess KC, Bowman AB. Genomic Instability Associated with p53 Knockdown in the Generation of Huntington's Disease Human Induced Pluripotent Stem Cells. Plos One. 11: e0150372. PMID 26982737 DOI: 10.1371/journal.pone.0150372  0.32
2015 Carson RP, Kelm ND, West KL, Does MD, Fu C, Weaver G, McBrier E, Parker B, Grier MD, Ess KC. Hypomyelination following deletion of Tsc2 in oligodendrocyte precursors. Annals of Clinical and Translational Neurology. 2: 1041-54. PMID 26734657 DOI: 10.1002/acn3.254  0.48
2015 Ess KC, Chugani HT. Dynamic tubers in tuberous sclerosis complex: A window for intervention? Neurology. 85: 1530-1. PMID 26432847 DOI: 10.1212/WNL.0000000000002056  0.48
2015 Kelm ND, West KL, Carson RP, Gochberg DF, Ess KC, Does MD. Evaluation of diffusion kurtosis imaging in ex vivo hypomyelinated mouse brains. Neuroimage. 124: 612-626. PMID 26400013 DOI: 10.1016/j.neuroimage.2015.09.028  0.48
2015 Chun YW, Balikov DA, Feaster TK, Williams CH, Sheng CC, Lee JB, Boire TC, Neely MD, Bellan LM, Ess KC, Bowman AB, Sung HJ, Hong CC. Combinatorial polymer matrices enhance in vitro maturation of human induced pluripotent stem cell-derived cardiomyocytes. Biomaterials. 67: 52-64. PMID 26204225 DOI: 10.1016/j.biomaterials.2015.07.004  0.48
2015 Kim SH, Wu SY, Baek JI, Choi SY, Su Y, Flynn CR, Gamse JT, Ess KC, Hardiman G, Lipschutz JH, Abumrad NN, Rockey DC. A post-developmental genetic screen for zebrafish models of inherited liver disease. Plos One. 10: e0125980. PMID 25950913 DOI: 10.1371/journal.pone.0125980  0.48
2015 Thomas LR, Wang Q, Grieb BC, Phan J, Foshage AM, Sun Q, Olejniczak ET, Clark T, Dey S, Lorey S, Alicie B, Howard GC, Cawthon B, Ess KC, Eischen CM, et al. Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC. Molecular Cell. 58: 440-52. PMID 25818646 DOI: 10.1016/j.molcel.2015.02.028  0.48
2015 de Vries PJ, Whittemore VH, Leclezio L, Byars AW, Dunn D, Ess KC, Hook D, King BH, Sahin M, Jansen A. Tuberous sclerosis associated neuropsychiatric disorders (TAND) and the TAND Checklist. Pediatric Neurology. 52: 25-35. PMID 25532776 DOI: 10.1016/j.pediatrneurol.2014.10.004  0.48
2015 Tidball AM, Bryan MR, Uhouse MA, Kumar KK, Aboud AA, Feist JE, Ess KC, Neely MD, Aschner M, Bowman AB. A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease. Human Molecular Genetics. 24: 1929-44. PMID 25489053 DOI: 10.1093/hmg/ddu609  0.48
2014 Aboud AA, Tidball AM, Kumar KK, Neely MD, Han B, Ess KC, Hong CC, Erikson KM, Hedera P, Bowman AB. PARK2 patient neuroprogenitors show increased mitochondrial sensitivity to copper. Neurobiology of Disease. 73: 204-212. PMID 25315681 DOI: 10.1016/j.nbd.2014.10.002  0.48
2014 West JD, Austin ED, Gaskill C, Marriott S, Baskir R, Bilousova G, Jean JC, Hemnes AR, Menon S, Bloodworth NC, Fessel JP, Kropski JA, Irwin D, Ware LB, Wheeler L, ... ... Ess KC, et al. Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertension. American Journal of Physiology. Cell Physiology. 307: C415-30. PMID 24871858 DOI: 10.1152/ajpcell.00057.2014  0.48
2013 Srinivasakumar N, Zaboikin M, Tidball AM, Aboud AA, Neely MD, Ess KC, Bowman AB, Schuening FG. Gammaretroviral vector encoding a fluorescent marker to facilitate detection of reprogrammed human fibroblasts during iPSC generation. Peerj. 1: e224. PMID 24392288 DOI: 10.7717/peerj.224  0.48
2013 Kim SH, Scott SA, Bennett MJ, Carson RP, Fessel J, Brown HA, Ess KC. Multi-organ abnormalities and mTORC1 activation in zebrafish model of multiple acyl-CoA dehydrogenase deficiency. Plos Genetics. 9: e1003563. PMID 23785301 DOI: 10.1371/journal.pgen.1003563  0.48
2013 Ess KC. Patient heal thyself: modeling and treating neurological disorders using patient-derived stem cells. Experimental Biology and Medicine (Maywood, N.J.). 238: 308-14. PMID 23598977 DOI: 10.1177/1535370213480713  0.48
2013 Kim SH, Kowalski ML, Carson RP, Bridges LR, Ess KC. Heterozygous inactivation of tsc2 enhances tumorigenesis in p53 mutant zebrafish. Disease Models & Mechanisms. 6: 925-33. PMID 23580196 DOI: 10.1242/dmm.011494  0.48
2013 Boglev Y, Badrock AP, Trotter AJ, Du Q, Richardson EJ, Parslow AC, Markmiller SJ, Hall NE, de Jong-Curtain TA, Ng AY, Verkade H, Ober EA, Field HA, Shin D, Shin CH, ... ... Ess KC, et al. Autophagy induction is a Tor- and Tp53-independent cell survival response in a zebrafish model of disrupted ribosome biogenesis. Plos Genetics. 9: e1003279. PMID 23408911 DOI: 10.1371/journal.pgen.1003279  0.48
2013 Fu C, Ess KC. Conditional and domain-specific inactivation of the Tsc2 gene in neural progenitor cells. Genesis (New York, N.Y. : 2000). 51: 284-92. PMID 23359422 DOI: 10.1002/dvg.22377  0.48
2013 Carson RP, Fu C, Winzenburger P, Ess KC. Deletion of Rictor in neural progenitor cells reveals contributions of mTORC2 signaling to tuberous sclerosis complex. Human Molecular Genetics. 22: 140-52. PMID 23049074 DOI: 10.1093/hmg/dds414  0.48
2013 Bowman AB, Ess KC, Kumar KK, Summar KL. Down Syndrome Neural Circuit Development and Function in the Heathy and Diseased Brain. 547-571. DOI: 10.1016/B978-0-12-397267-5.00130-8  0.48
2012 Aboud AA, Tidball AM, Kumar KK, Neely MD, Ess KC, Erikson KM, Bowman AB. Genetic risk for Parkinson's disease correlates with alterations in neuronal manganese sensitivity between two human subjects. Neurotoxicology. 33: 1443-9. PMID 23099318 DOI: 10.1016/j.neuro.2012.10.009  0.48
2012 Neely MD, Litt MJ, Tidball AM, Li GG, Aboud AA, Hopkins CR, Chamberlin R, Hong CC, Ess KC, Bowman AB. DMH1, a highly selective small molecule BMP inhibitor promotes neurogenesis of hiPSCs: comparison of PAX6 and SOX1 expression during neural induction. Acs Chemical Neuroscience. 3: 482-91. PMID 22860217 DOI: 10.1021/cn300029t  0.48
2012 Armour EA, Carson RP, Ess KC. Cystogenesis and elongated primary cilia in Tsc1-deficient distal convoluted tubules. American Journal of Physiology. Renal Physiology. 303: F584-92. PMID 22674026 DOI: 10.1152/ajprenal.00141.2012  0.48
2012 Ess KC, Roach ES. New therapies for tuber-less sclerosis: white matter matters? Neurology. 78: 520-1. PMID 22262747 DOI: 10.1212/WNL.0b013e318248a232  0.48
2012 Fu C, Cawthon B, Clinkscales W, Bruce A, Winzenburger P, Ess KC. GABAergic interneuron development and function is modulated by the Tsc1 gene. Cerebral Cortex (New York, N.Y. : 1991). 22: 2111-9. PMID 22021912 DOI: 10.1093/cercor/bhr300  0.48
2012 Carson RP, Van Nielen DL, Winzenburger PA, Ess KC. Neuronal and glia abnormalities in Tsc1-deficient forebrain and partial rescue by rapamycin. Neurobiology of Disease. 45: 369-80. PMID 21907282 DOI: 10.1016/j.nbd.2011.08.024  0.48
2011 Kim SH, Speirs CK, Solnica-Krezel L, Ess KC. Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin. Disease Models & Mechanisms. 4: 255-67. PMID 20959633 DOI: 10.1242/dmm.005587  0.48
2011 Neely MD, Tidball AM, Aboud AA, Ess KC, Bowman AB. Induced pluripotent stem cells (iPSCs): An emerging model system for the study of human neurotoxicology Neuromethods. 56: 27-61. DOI: 10.1007/978-1-61779-077-5_2  0.48
2010 Ess KC. Tuberous sclerosis complex: a brave new world? Current Opinion in Neurology. 23: 189-93. PMID 20087180 DOI: 10.1097/WCO.0b013e32832c4ff5  0.48
2009 Ess KC. Tuberous sclerosis complex: everything old is new again. Journal of Neurodevelopmental Disorders. 1: 141-9. PMID 21547713 DOI: 10.1007/s11689-009-9014-y  0.48
2009 Ess KC. Treatment of infantile spasms in tuberous sclerosis complex: dismal outcomes but future hope? Nature Clinical Practice. Neurology. 5: 72-3. PMID 19107107 DOI: 10.1038/ncpneuro0994  0.48
2009 Ess KC. Modeling tuberous sclerosis complex: Brain development and hyperexcitability Neuromethods. 40: 75-86. DOI: 10.1007/978-1-60327-263-6_5  0.48
2007 Zeng LH, Ouyang Y, Gazit V, Cirrito JR, Jansen LA, Ess KC, Yamada KA, Wozniak DF, Holtzman DM, Gutmann DH, Wong M. Abnormal glutamate homeostasis and impaired synaptic plasticity and learning in a mouse model of tuberous sclerosis complex. Neurobiology of Disease. 28: 184-96. PMID 17714952 DOI: 10.1016/j.nbd.2007.07.015  0.48
2006 Ess KC. The neurobiology of tuberous sclerosis complex. Seminars in Pediatric Neurology. 13: 37-42. PMID 16818174 DOI: 10.1016/j.spen.2006.01.009  0.48
2005 Ess KC, Kamp CA, Tu BP, Gutmann DH. Developmental origin of subependymal giant cell astrocytoma in tuberous sclerosis complex. Neurology. 64: 1446-9. PMID 15851742 DOI: 10.1212/01.WNL.0000158653.81008.49  0.48
2004 Ess KC, Uhlmann EJ, Li W, Li H, Declue JE, Crino PB, Gutmann DH. Expression profiling in tuberous sclerosis complex (TSC) knockout mouse astrocytes to characterize human TSC brain pathology. Glia. 46: 28-40. PMID 14999811 DOI: 10.1002/glia.10324  0.48
2003 Wong M, Ess KC, Uhlmann EJ, Jansen LA, Li W, Crino PB, Mennerick S, Yamada KA, Gutmann DH. Impaired glial glutamate transport in a mouse tuberous sclerosis epilepsy model. Annals of Neurology. 54: 251-6. PMID 12891680 DOI: 10.1002/ana.10648  0.48
2002 Wong M, Ess K, Landt M. Cerebrospinal fluid neuron-specific enolase following seizures in children: Role of etiology Journal of Child Neurology. 17: 261-264. PMID 12088080  0.48
1999 Ess KC, Witte DP, Bascomb CP, Aronow BJ. Diverse developing mouse lineages exhibit high-level c-Myb expression in immature cells and loss of expression upon differentiation. Oncogene. 18: 1103-11. PMID 10023687 DOI: 10.1038/sj.onc.1202387  0.48
1996 Hutton JJ, Ess KC, Witte DP, Aronow BJ. Winner of the Theodore E. Woodward Award: c-Myb and the coordinate regulation of thymic genes. Transactions of the American Clinical and Climatological Association. 107: 115-24. PMID 8725565  0.48
1996 Ess KC, Hutton JJ, Aronow BJ. A central role for c-myb in cortical thymocyte gene regulation Journal of Investigative Medicine. 44: 205a.  0.48
1995 Ess K, Chen H, Kier A, Brackenbury R. Suppression of tumorigenicity, but not invasion, in glioblastoma/HeLa cell hybrids Journal of Cellular Physiology. 162: 341-347. PMID 7860642 DOI: 10.1002/jcp.1041620306  0.48
1995 Ess KC, Whitaker TL, Cost GJ, Witte DP, Hutton JJ, Aronow BJ. A central role for a single c-Myb binding site in a thymic locus control region. Molecular and Cellular Biology. 15: 5707-15. PMID 7565722  0.48
1994 Ess KC, Hutton JJ, Aronow BJ. Double-stranded phosphorothioate oligonucleotide modulation of gene expression. Annals of the New York Academy of Sciences. 716: 321-3. PMID 8024203 DOI: 10.1111/j.1749-6632.1994.tb21722.x  0.48
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