Nicholas Maragakis - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
ALS, stem cells

85 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Hoye ML, Regan MR, Jensen LA, Lake AM, Reddy LV, Vidensky S, Richard JP, Maragakis NJ, Rothstein JD, Dougherty JD, Miller TM. Motor neuron-derived microRNAs cause astrocyte dysfunction in amyotrophic lateral sclerosis. Brain : a Journal of Neurology. PMID 30007309 DOI: 10.1093/brain/awy182  1
2018 Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, ... ... Maragakis NJ, et al. Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Neuron. 97: 1268-1283.e6. PMID 29566793 DOI: 10.1016/j.neuron.2018.02.027  1
2016 Bali T, Self W, Liu J, Siddique T, Wang LH, Bird TD, Ratti E, Atassi N, Boylan KB, Glass JD, Maragakis NJ, Caress JB, McCluskey LF, Appel SH, Wymer JP, et al. Defining SOD1 ALS natural history to guide therapeutic clinical trial design. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 27261500 DOI: 10.1136/jnnp-2016-313521  1
2016 Choi IY, Lim H, Estrellas K, Mula J, Cohen TV, Zhang Y, Donnelly CJ, Richard JP, Kim YJ, Kim H, Kazuki Y, Oshimura M, Li HL, Hotta A, Rothstein J, ... Maragakis N, et al. Concordant but Varied Phenotypes among Duchenne Muscular Dystrophy Patient-Specific Myoblasts Derived using a Human iPSC-Based Model. Cell Reports. PMID 27239027 DOI: 10.1016/j.celrep.2016.05.016  1
2016 Qosa H, Lichter J, Sarlo M, Markandaiah SS, McAvoy K, Richard JP, Jablonski MR, Maragakis NJ, Pasinelli P, Trotti D. Astrocytes drive upregulation of the multidrug resistance transporter ABCB1 (P-Glycoprotein) in endothelial cells of the blood-brain barrier in mutant superoxide dismutase 1-linked amyotrophic lateral sclerosis. Glia. PMID 27158936 DOI: 10.1002/glia.23003  1
2016 Fournier CN, Murphy A, Loci L, Mitsumoto H, Lomen-Hoerth C, Kisanuki Y, Simmons Z, Maragakis NJ, McVey AL, Al-Lahham T, Heiman-Patterson TD, Andrews J, McDonnell E, Cudkowicz M, Atassi N. Primary Lateral Sclerosis and Early Upper Motor Neuron Disease: Characteristics of a Cross-Sectional Population. Journal of Clinical Neuromuscular Disease. 17: 99-105. PMID 26905909 DOI: 10.1097/CND.0000000000000102  1
2015 Zhang PW, Haidet-Phillips AM, Pham JT, Lee Y, Huo Y, Tienari PJ, Maragakis NJ, Sattler R, Rothstein JD. Generation of GFAP::GFP astrocyte reporter lines from human adult fibroblast-derived iPS cells using zinc-finger nuclease technology. Glia. PMID 26295203 DOI: 10.1002/glia.22903  1
2015 Li K, Javed E, Scura D, Hala TJ, Seetharam S, Falnikar A, Richard JP, Chorath A, Maragakis NJ, Wright MC, Lepore AC. Human iPS cell-derived astrocyte transplants preserve respiratory function after spinal cord injury. Experimental Neurology. PMID 26216662 DOI: 10.1016/j.expneurol.2015.07.020  1
2015 Paganoni S, Hyman T, Shui A, Allred P, Harms M, Liu J, Maragakis N, Schoenfeld D, Yu H, Atassi N, Cudkowicz M, Miller TM. Pre-morbid type 2 diabetes mellitus is not a prognostic factor in amyotrophic lateral sclerosis. Muscle & Nerve. PMID 25900666 DOI: 10.1002/mus.24688  1
2015 Li Y, Balasubramanian U, Cohen D, Zhang PW, Mosmiller E, Sattler R, Maragakis NJ, Rothstein JD. A comprehensive library of familial human amyotrophic lateral sclerosis induced pluripotent stem cells. Plos One. 10: e0118266. PMID 25760436 DOI: 10.1371/journal.pone.0118266  1
2015 Grunseich C, Schindler AB, Chen KL, Bakar D, Mankodi A, Traslavina R, Ray-Chaudhury A, Lehky TJ, Baker EH, Maragakis NJ, Tifft CJ, Fischbeck KH. Peripheral neuropathy in a family with Sandhoff disease and SH3TC2 deficiency. Journal of Neurology. 262: 1066-8. PMID 25736553 DOI: 10.1007/s00415-015-7683-x  1
2015 Haidet-Phillips AM, Doreswamy A, Gross SK, Tang X, Campanelli JT, Maragakis NJ. Human glial progenitor engraftment and gene expression is independent of the ALS environment. Experimental Neurology. 264: 188-99. PMID 25523812 DOI: 10.1016/j.expneurol.2014.12.011  1
2015 Li K, Javed E, Hala TJ, Sannie D, Regan KA, Maragakis NJ, Wright MC, Poulsen DJ, Lepore AC. Transplantation of glial progenitors that overexpress glutamate transporter GLT1 preserves diaphragm function following cervical SCI. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 533-48. PMID 25492561 DOI: 10.1038/mt.2014.236  1
2015 Richard JP, Maragakis NJ. Induced pluripotent stem cells from ALS patients for disease modeling. Brain Research. 1607: 15-25. PMID 25223906 DOI: 10.1016/j.brainres.2014.09.017  1
2015 Bedlack R, Quinn C, Karam C, Sherman A, Ostrow L, Hardiman O, Heiman-Patterson T, Gutmann L, Bromberg M, Carter G, Kabashi E, Bertorini T, Mozaffar T, Andersen P, Dietz J, ... ... Maragakis N, et al. ALSUntangled No. 29: MitoQ Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 16: 427-429. DOI: 10.3109/21678421.2015.1050897  1
2015 Bedlack R, Quinn C, Karam C, Sherman A, Ostrow L, Hardiman O, Heiman-Patterson T, Gutmann L, Bromberg M, Carter G, Kabashi E, Bertorini T, Mozaffar T, Andersen P, Dietz J, ... ... Maragakis N, et al. ALSUntangled: Introducing the table of evidence Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 16: 142-145. DOI: 10.3109/21678421.2014.987476  1
2014 Haidet-Phillips AM, Roybon L, Gross SK, Tuteja A, Donnelly CJ, Richard JP, Ko M, Sherman A, Eggan K, Henderson CE, Maragakis NJ. Gene profiling of human induced pluripotent stem cell-derived astrocyte progenitors following spinal cord engraftment. Stem Cells Translational Medicine. 3: 575-85. PMID 24604284 DOI: 10.5966/sctm.2013-0153  1
2014 Haeusler AR, Donnelly CJ, Periz G, Simko EA, Shaw PG, Kim MS, Maragakis NJ, Troncoso JC, Pandey A, Sattler R, Rothstein JD, Wang J. C9orf72 nucleotide repeat structures initiate molecular cascades of disease. Nature. 507: 195-200. PMID 24598541 DOI: 10.1038/nature13124  1
2014 Rutkove SB, Caress JB, Cartwright MS, Burns TM, Warder J, David WS, Goyal N, Maragakis NJ, Benatar M, Sharma KR, Narayanaswami P, Raynor EM, Watson ML, Shefner JM. Electrical impedance myography correlates with standard measures of ALS severity. Muscle & Nerve. 49: 441-3. PMID 24273034 DOI: 10.1002/mus.24128  1
2014 Bedlack R, Quinn C, Karam C, Sherman A, Ostrow L, Hardiman O, Heiman-Patterson T, Gutmann L, Bromberg M, Carter G, Kabashi E, Bertorini T, Mozaffar T, Andersen P, Dietz J, ... ... Maragakis N, et al. ALSUntangled no. 26: Lunasin Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 15: 622-626. DOI: 10.3109/21678421.2014.959297  1
2013 Donnelly CJ, Zhang PW, Pham JT, Haeusler AR, Heusler AR, Mistry NA, Vidensky S, Daley EL, Poth EM, Hoover B, Fines DM, Maragakis N, Tienari PJ, Petrucelli L, Traynor BJ, et al. RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention. Neuron. 80: 415-28. PMID 24139042 DOI: 10.1016/j.neuron.2013.10.015  1
2013 Haidet-Phillips AM, Gross SK, Williams T, Tuteja A, Sherman A, Ko M, Jeong YH, Wong PC, Maragakis NJ. Altered astrocytic expression of TDP-43 does not influence motor neuron survival. Experimental Neurology. 250: 250-9. PMID 24120466 DOI: 10.1016/j.expneurol.2013.10.004  1
2013 Chesi A, Staahl BT, Jovičić A, Couthouis J, Fasolino M, Raphael AR, Yamazaki T, Elias L, Polak M, Kelly C, Williams KL, Fifita JA, Maragakis NJ, Nicholson GA, King OD, et al. Exome sequencing to identify de novo mutations in sporadic ALS trios. Nature Neuroscience. 16: 851-5. PMID 23708140 DOI: 10.1038/nn.3412  1
2013 Chad DA, Rowland LP, Armon C, Bedlack R, Durham H, Factor-Litvak P, Heiman-Patterson T, Heitzman D, Lacomis D, Ludolph A, Maragakis N, Miller R, Pattee G, Shoesmith C, Sorenson E, et al. Peer recommendations on how to improve clinical research, and Conference wrap-up. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 67-73. PMID 23678882 DOI: 10.3109/21678421.2013.778605  1
2013 Turner MR, Bowser R, Bruijn L, Dupuis L, Ludolph A, McGrath M, Manfredi G, Maragakis N, Miller RG, Pullman SL, Rutkove SB, Shaw PJ, Shefner J, Fischbeck KH. Mechanisms, models and biomarkers in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 19-32. PMID 23678877 DOI: 10.3109/21678421.2013.778554  1
2013 Fournier C, Bedlack B, Hardiman O, Heiman-Patterson T, Gutmann L, Bromberg M, Ostrow L, Carter G, Kabashi E, Bertorini T, Mozaffar T, Andersen P, Dietz J, Gamez J, ... ... Maragakis N, et al. ALS Untangled No. 20: the Deanna protocol. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 319-23. PMID 23638638 DOI: 10.3109/21678421.2013.788405  1
2013 Roth NM, Saidha S, Zimmermann H, Brandt AU, Oberwahrenbrock T, Maragakis NJ, Tumani H, Ludolph AC, Meyer T, Calabresi PA, Paul F. Optical coherence tomography does not support optic nerve involvement in amyotrophic lateral sclerosis. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 20: 1170-6. PMID 23582075 DOI: 10.1111/ene.12146  1
2013 Donnelly CJ, Zhang PW, Pham JT, Haeusler AR, Mistry NA, Vidensky S, Daley EL, Poth EM, Hoover B, Fines DM, Maragakis N, Tienari PJ, Petrucelli L, Traynor BJ, Wang J, et al. RNA Toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention [Neuron, 79, (September 18, 2013), 1222-1231] Neuron. 80: 1102. DOI: 10.1016/j.neuron.2013.10.055  1
2012 Teng YD, Benn SC, Kalkanis SN, Shefner JM, Onario RC, Cheng B, Lachyankar MB, Marconi M, Li J, Yu D, Han I, Maragakis NJ, Lládo J, Erkmen K, Redmond DE, et al. Multimodal actions of neural stem cells in a mouse model of ALS: a meta-analysis. Science Translational Medicine. 4: 165ra164. PMID 23253611 DOI: 10.1126/scitranslmed.3004579  1
2012 Almad AA, Maragakis NJ. Glia: an emerging target for neurological disease therapy. Stem Cell Research & Therapy. 3: 37. PMID 23021042 DOI: 10.1186/scrt128  1
2012 Wray S, Self M, Lewis PA, Taanman JW, Ryan NS, Mahoney CJ, Liang Y, Devine MJ, Sheerin UM, Houlden H, Morris HR, Healy D, ... ... Maragakis NJ, et al. Creation of an open-access, mutation-defined fibroblast resource for neurological disease research. Plos One. 7: e43099. PMID 22952635 DOI: 10.1371/journal.pone.0043099  1
2012 Murinson BB, Haughey NJ, Maragakis NJ. Selected statins produce rapid spinal motor neuron loss in vitro. Bmc Musculoskeletal Disorders. 13: 100. PMID 22703530 DOI: 10.1186/1471-2474-13-100  1
2012 Rutkove SB, Caress JB, Cartwright MS, Burns TM, Warder J, David WS, Goyal N, Maragakis NJ, Clawson L, Benatar M, Usher S, Sharma KR, Gautam S, Narayanaswami P, Raynor EM, et al. Electrical impedance myography as a biomarker to assess ALS progression. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 13: 439-45. PMID 22670883 DOI: 10.3109/17482968.2012.688837  1
2012 Shefner J, Cedarbaum JM, Cudkowicz ME, Maragakis N, Lee J, Jones D, Watson ML, Mahoney K, Chen M, Saikali K, Mao J, Russell AJ, Hansen RL, Malik F, Wolff AA, et al. Safety, tolerability and pharmacodynamics of a skeletal muscle activator in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 13: 430-8. PMID 22591195 DOI: 10.3109/17482968.2012.684214  1
2012 Jablonski MR, Jacob DA, Campos C, Miller DS, Maragakis NJ, Pasinelli P, Trotti D. Selective increase of two ABC drug efflux transporters at the blood-spinal cord barrier suggests induced pharmacoresistance in ALS. Neurobiology of Disease. 47: 194-200. PMID 22521463 DOI: 10.1016/j.nbd.2012.03.040  1
2012 Wadhwa V, Thakkar RS, Maragakis N, Höke A, Sumner CJ, Lloyd TE, Carrino JA, Belzberg AJ, Chhabra A. Sciatic nerve tumor and tumor-like lesions - uncommon pathologies. Skeletal Radiology. 41: 763-74. PMID 22410805 DOI: 10.1007/s00256-012-1384-7  1
2011 Lepore AC, O'Donnell J, Kim AS, Williams T, Tuteja A, Rao MS, Kelley LL, Campanelli JT, Maragakis NJ. Human glial-restricted progenitor transplantation into cervical spinal cord of the SOD1 mouse model of ALS. Plos One. 6: e25968. PMID 21998733 DOI: 10.1371/journal.pone.0025968  1
2011 Papadeas ST, Kraig SE, O'Banion C, Lepore AC, Maragakis NJ. Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo. Proceedings of the National Academy of Sciences of the United States of America. 108: 17803-8. PMID 21969586 DOI: 10.1073/pnas.1103141108  1
2011 Lepore AC, Maragakis NJ. Stem cell transplantation for spinal cord neurodegeneration. Methods in Molecular Biology (Clifton, N.J.). 793: 479-93. PMID 21913120 DOI: 10.1007/978-1-61779-328-8_31  1
2011 Lepore AC, O'Donnell J, Kim AS, Yang EJ, Tuteja A, Haidet-Phillips A, O'Banion CP, Maragakis NJ. Reduction in expression of the astrocyte glutamate transporter, GLT1, worsens functional and histological outcomes following traumatic spinal cord injury. Glia. 59: 1996-2005. PMID 21882244 DOI: 10.1002/glia.21241  1
2011 Shefner JM, Watson ML, Simionescu L, Caress JB, Burns TM, Maragakis NJ, Benatar M, David WS, Sharma KR, Rutkove SB. Multipoint incremental motor unit number estimation as an outcome measure in ALS. Neurology. 77: 235-41. PMID 21676915 DOI: 10.1212/WNL.0b013e318225aabf  1
2011 Lepore AC, O'Donnell J, Bonner JF, Paul C, Miller ME, Rauck B, Kushner RA, Rothstein JD, Fischer I, Maragakis NJ. Spatial and temporal changes in promoter activity of the astrocyte glutamate transporter GLT1 following traumatic spinal cord injury. Journal of Neuroscience Research. 89: 1001-17. PMID 21488085 DOI: 10.1002/jnr.22624  1
2011 Heiman-Patterson TD, Sher RB, Blankenhorn EA, Alexander G, Deitch JS, Kunst CB, Maragakis N, Cox G. Effect of genetic background on phenotype variability in transgenic mouse models of amyotrophic lateral sclerosis: a window of opportunity in the search for genetic modifiers. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 12: 79-86. PMID 21241159 DOI: 10.3109/17482968.2010.550626  1
2011 Maragakis N, Rothstein JD. New treatments in amyotrophic lateral sclerosis. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 370-2. PMID 21116264 DOI: 10.1038/npp.2010.140  1
2010 Maragakis NJ. Stem cells and the ALS neurologist. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 11: 417-23. PMID 20509745 DOI: 10.3109/17482968.2010.489116  1
2010 Lepore AC, Tolmie C, O'Donnell J, Wright MC, Dejea C, Rauck B, Hoke A, Ignagni AR, Onders RP, Maragakis NJ. Peripheral hyperstimulation alters site of disease onset and course in SOD1 rats. Neurobiology of Disease. 39: 252-64. PMID 20381620 DOI: 10.1016/j.nbd.2010.03.021  1
2010 Maragakis NJ. Motor neuron disease: progressive muscular atrophy in the ALS spectrum. Nature Reviews. Neurology. 6: 187-8. PMID 20379201 DOI: 10.1038/nrneurol.2010.29  1
2009 Papadeas ST, Maragakis NJ. Advances in stem cell research for Amyotrophic Lateral Sclerosis. Current Opinion in Biotechnology. 20: 545-51. PMID 19819686 DOI: 10.1016/j.copbio.2009.09.003  1
2009 Xue H, Wu S, Papadeas ST, Spusta S, Swistowska AM, MacArthur CC, Mattson MP, Maragakis NJ, Capecchi MR, Rao MS, Zeng X, Liu Y. A targeted neuroglial reporter line generated by homologous recombination in human embryonic stem cells. Stem Cells (Dayton, Ohio). 27: 1836-46. PMID 19544414 DOI: 10.1002/stem.129  1
2009 Maragakis NJ. Rethinking a drug treatment failure on a traditional ALS target. Experimental Neurology. 216: 254-7. PMID 19309797 DOI: 10.1016/j.expneurol.2008.12.025  1
2009 Lechtzin N, Maragakis NJ, Kimball R, Busse A, Hoffman V, Clawson L. Accurate ALSFRS-R scores can be generated from retrospective review of clinic notes. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 10: 244-7. PMID 18985465 DOI: 10.1080/17482960802502993  1
2008 Murinson BB, Maragakis NJ, Jacobson TA. Fluvastatin, rhabdomyolysis, and myotoxicity. Mayo Clinic Proceedings. 83: 1296; author reply 1. PMID 18990330 DOI: 10.4065/83.11.1296  1
2008 Lepore AC, Rauck B, Dejea C, Pardo AC, Rao MS, Rothstein JD, Maragakis NJ. Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease. Nature Neuroscience. 11: 1294-301. PMID 18931666 DOI: 10.1038/nn.2210  1
2008 Bedlack RS, Maragakis N, Heiman-Patterson T. Lithium may slow progression of amyotrophic lateral sclerosis, but further study is needed. Proceedings of the National Academy of Sciences of the United States of America. 105: E17; author reply E1. PMID 18417448 DOI: 10.1073/pnas.0801762105  1
2008 Lepore AC, Dejea C, Carmen J, Rauck B, Kerr DA, Sofroniew MV, Maragakis NJ. Selective ablation of proliferating astrocytes does not affect disease outcome in either acute or chronic models of motor neuron degeneration. Experimental Neurology. 211: 423-32. PMID 18410928 DOI: 10.1016/j.expneurol.2008.02.020  1
2008 Laird FM, Farah MH, Ackerley S, Hoke A, Maragakis N, Rothstein JD, Griffin J, Price DL, Martin LJ, Wong PC. Motor neuron disease occurring in a mutant dynactin mouse model is characterized by defects in vesicular trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1997-2005. PMID 18305234 DOI: 10.1523/JNEUROSCI.4231-07.2008  1
2008 Magnus T, Carmen J, Deleon J, Xue H, Pardo AC, Lepore AC, Mattson MP, Rao MS, Maragakis NJ. Adult glial precursor proliferation in mutant SOD1G93A mice. Glia. 56: 200-8. PMID 18023016 DOI: 10.1002/glia.20604  1
2008 Li L, Lundkvist A, Andersson D, Wilhelmsson U, Nagai N, Pardo AC, Nodin C, StÃ¥hlberg A, Aprico K, Larsson K, Yabe T, Moons L, Fotheringham A, Davies I, Carmeliet P, ... ... Maragakis N, et al. Protective role of reactive astrocytes in brain ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 468-81. PMID 17726492 DOI: 10.1038/sj.jcbfm.9600546  1
2007 Gwinn K, Corriveau RA, Mitsumoto H, Bednarz K, Brown RH, Cudkowicz M, Gordon PH, Hardy J, Kasarskis EJ, Kaufmann P, Miller R, Sorenson E, Tandan R, Traynor BJ, Nash J, et al. Amyotrophic lateral sclerosis: an emerging era of collaborative gene discovery. Plos One. 2: e1254. PMID 18060051 DOI: 10.1371/journal.pone.0001254  1
2007 Lepore AC, Haenggeli C, Gasmi M, Bishop KM, Bartus RT, Maragakis NJ, Rothstein JD. Intraparenchymal spinal cord delivery of adeno-associated virus IGF-1 is protective in the SOD1G93A model of ALS. Brain Research. 1185: 256-65. PMID 17963733 DOI: 10.1016/j.brainres.2007.09.034  1
2007 Luo Y, Xue H, Pardo AC, Mattson MP, Rao MS, Maragakis NJ. Impaired SDF1/CXCR4 signaling in glial progenitors derived from SOD1(G93A) mice. Journal of Neuroscience Research. 85: 2422-32. PMID 17567884 DOI: 10.1002/jnr.21398  1
2007 Lepore AC, Maragakis NJ. Targeted stem cell transplantation strategies in ALS. Neurochemistry International. 50: 966-75. PMID 17055612 DOI: 10.1016/j.neuint.2006.09.005  1
2007 Maragakis NJ, Rothstein JD. Motor Neuron Disease: Amyotrophic Lateral Sclerosis Molecular Neurology. 307-319. DOI: 10.1016/B978-012369509-3.50022-6  1
2007 Maragakis NJ, Rothstein JD. Amyotrophic lateral sclerosis: Idiopathic and inherited Neurobiology of Disease. 521-535. DOI: 10.1016/B978-012088592-3/50048-7  1
2006 Kim YS, Martinez T, Deshpande DM, Drummond J, Provost-Javier K, Williams A, McGurk J, Maragakis N, Song H, Ming GL, Kerr DA. Correction of humoral derangements from mutant superoxide dismutase 1 spinal cord. Annals of Neurology. 60: 716-28. PMID 17192933 DOI: 10.1002/ana.21034  1
2006 Maragakis NJ, Rothstein JD. Mechanisms of Disease: astrocytes in neurodegenerative disease. Nature Clinical Practice. Neurology. 2: 679-89. PMID 17117171 DOI: 10.1038/ncpneuro0355  1
2006 Deshpande DM, Kim YS, Martinez T, Carmen J, Dike S, Shats I, Rubin LL, Drummond J, Krishnan C, Hoke A, Maragakis N, Shefner J, Rothstein JD, Kerr DA. Recovery from paralysis in adult rats using embryonic stem cells. Annals of Neurology. 60: 32-44. PMID 16802299 DOI: 10.1002/ana.20901  1
2006 Pardo AC, Wong V, Benson LM, Dykes M, Tanaka K, Rothstein JD, Maragakis NJ. Loss of the astrocyte glutamate transporter GLT1 modifies disease in SOD1(G93A) mice. Experimental Neurology. 201: 120-30. PMID 16753145 DOI: 10.1016/j.expneurol.2006.03.028  1
2006 Ganel R, Ho T, Maragakis NJ, Jackson M, Steiner JP, Rothstein JD. Selective up-regulation of the glial Na+-dependent glutamate transporter GLT1 by a neuroimmunophilin ligand results in neuroprotection. Neurobiology of Disease. 21: 556-67. PMID 16274998 DOI: 10.1016/j.nbd.2005.08.014  1
2006 Lladó J, Haenggeli C, Pardo A, Wong V, Benson L, Coccia C, Rothstein JD, Shefner JM, Maragakis NJ. Degeneration of respiratory motor neurons in the SOD1 G93A transgenic rat model of ALS. Neurobiology of Disease. 21: 110-8. PMID 16084734 DOI: 10.1016/j.nbd.2005.06.019  1
2006 Maragakis NJ, Pardo AC. Amyotrophic lateral sclerosis presenting with a clivus mass and dysarthria Journal of Clinical Neuromuscular Disease. 8: 80-82. DOI: 10.1097/CND.0b013e31802b4c97  1
2005 Maragakis NJ, Rao MS, Llado J, Wong V, Xue H, Pardo A, Herring J, Kerr D, Coccia C, Rothstein JD. Glial restricted precursors protect against chronic glutamate neurotoxicity of motor neurons in vitro. Glia. 50: 145-59. PMID 15657939 DOI: 10.1002/glia.20161  1
2004 Lladó J, Haenggeli C, Maragakis NJ, Snyder EY, Rothstein JD. Neural stem cells protect against glutamate-induced excitotoxicity and promote survival of injured motor neurons through the secretion of neurotrophic factors. Molecular and Cellular Neurosciences. 27: 322-31. PMID 15519246 DOI: 10.1016/j.mcn.2004.07.010  1
2004 Darman J, Backovic S, Dike S, Maragakis NJ, Krishnan C, Rothstein JD, Irani DN, Kerr DA. Viral-induced spinal motor neuron death is non-cell-autonomous and involves glutamate excitotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7566-75. PMID 15329404 DOI: 10.1523/JNEUROSCI.2002-04.2004  1
2004 Maragakis NJ, Rothstein JD. Glutamate transporters: animal models to neurologic disease. Neurobiology of Disease. 15: 461-73. PMID 15056453 DOI: 10.1016/j.nbd.2003.12.007  1
2004 Maragakis NJ, Dykes-Hoberg M, Rothstein JD. Altered expression of the glutamate transporter EAAT2b in neurological disease. Annals of Neurology. 55: 469-77. PMID 15048885 DOI: 10.1002/ana.20003  1
2004 Maragakis NJ, Dietrich J, Wong V, Xue H, Mayer-Proschel M, Rao MS, Rothstein JD. Glutamate transporter expression and function in human glial progenitors. Glia. 45: 133-43. PMID 14730707 DOI: 10.1002/glia.10310  1
2003 Ueki T, Tanaka M, Yamashita K, Mikawa S, Qiu Z, Maragakis NJ, Hevner RF, Miura N, Sugimura H, Sato K. A novel secretory factor, Neurogenesin-1, provides neurogenic environmental cues for neural stem cells in the adult hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 11732-40. PMID 14684875  1
2003 Kerr DA, Lladó J, Shamblott MJ, Maragakis NJ, Irani DN, Crawford TO, Krishnan C, Dike S, Gearhart JD, Rothstein JD. Human embryonic germ cell derivatives facilitate motor recovery of rats with diffuse motor neuron injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5131-40. PMID 12832537  1
2003 Maragakis NJ, Jackson M, Ganel R, Rothstein JD. Topiramate protects against motor neuron degeneration in organotypic spinal cord cultures but not in G93A SOD1 transgenic mice. Neuroscience Letters. 338: 107-10. PMID 12566164 DOI: 10.1016/S0304-3940(02)01386-1  1
2002 Patel SA, Maragakis NJ. Amyotrophic lateral sclerosis: pathogenesis, differential diagnoses, and potential interventions. The Journal of Spinal Cord Medicine. 25: 262-73. PMID 12482167 DOI: 10.1017/CBO9780511980053.013  1
2002 Howland DS, Liu J, She Y, Goad B, Maragakis NJ, Kim B, Erickson J, Kulik J, DeVito L, Psaltis G, DeGennaro LJ, Cleveland DW, Rothstein JD. Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS). Proceedings of the National Academy of Sciences of the United States of America. 99: 1604-9. PMID 11818550 DOI: 10.1073/pnas.032539299  1
2001 Maragakis NJ, Rothstein JD. Glutamate transporters in neurologic disease. Archives of Neurology. 58: 365-70. PMID 11255439  1
2000 Coffeen CM, McKenna CE, Koeppen AH, Plaster NM, Maragakis N, Mihalopoulos J, Schwankhaus JD, Flanigan KM, Gregg RG, Ptácek LJ, Fu YH. Genetic localization of an autosomal dominant leukodystrophy mimicking chronic progressive multiple sclerosis to chromosome 5q31. Human Molecular Genetics. 9: 787-93. PMID 10749986  1
1992 Irwin RP, Maragakis NJ, Rogawski MA, Purdy RH, Farb DH, Paul SM. Pregnenolone sulfate augments NMDA receptor mediated increases in intracellular Ca2+ in cultured rat hippocampal neurons. Neuroscience Letters. 141: 30-4. PMID 1387199 DOI: 10.1016/0304-3940(92)90327-4  1
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