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Jean-Philippe GUILLOUX, Ph.D. - Publications

Pharmacology Université Paris Sud, Bures-sur-Yvette, Île-de-France, France 

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Gardier A, Nguyen TML, Defaix C, Mendez-David I, Guilloux J, Alvarez J, McGowan JC, David DJ, Denny CA. Efficacy of Intranasal Delivery of (R,S)-Ketamine to the Mouse Brain Biological Psychiatry. 87: S390-S391. DOI: 10.1016/j.biopsych.2020.02.999  0.552
2020 Mendez-David I, Guilloux J, Shah A, Tritschler L, Defaix C, Fossati P, Colle R, Hen R, Denny C, Gardier A, Corruble E, David D. Serotonin 3 Receptor Blockade is Involved in Vortioxetine -Induced Prevention of Anxiety/Depression Relapse Phenotype Biological Psychiatry. 87. DOI: 10.1016/J.Biopsych.2020.02.1125  0.792
2020 Prevot T, Li G, Knutson D, Mondal P, Mian Y, Guilloux J, Mendez-David I, David D, Cook J, Sibille E. Improved Cognitive Functions and Neurotrophic Effects of a Novel Molecule Enhancing α5-GABA-A Receptor Function in Adult or Aged Mice Biological Psychiatry. 87: S404. DOI: 10.1016/J.Biopsych.2020.02.1032  0.726
2019 Mendez-David I, Guilloux J, Tritschler L, Defaix C, Faye C, Colle R, Corruble E, Gardier A, Fossati P, David D. S137. Long-Term Effects of Vortioxetine (Lu AA21004) on Adult Hippocampal Neurogenesis Prevents Reinstatement of Anxiety/Depression-Like Phenotype in Mice Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.888  0.76
2019 Loan Nguyen TM, Defaix C, Mendez-David I, Pham TH, Guilloux J, Etting I, Alvarez J, McGowan JC, David DJ, Denny CA, Gardier A. S136. Is Ketamine Metabolism to Norketamine and (2R,6R)-HNK Necessary for its Sustained Antidepressant-Like Activity and Cortical Neurotransmitter Release in Mice? Biological Psychiatry. 85: S349. DOI: 10.1016/j.biopsych.2019.03.887  0.572
2019 Guilloux J, Mendez-David I, Henry C, Attali D, Plaze M, Gardier A, Gaillard R, David D. S132. Peripheral Signature of Response to Electroconvulsive Seizure in a Murine Model of Anxiety/Depression Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.883  0.729
2018 Tritschler L, Gaillard R, Gardier AM, David DJ, Guilloux JP. [Consequences of the monoaminergic systems cross-talk in the antidepressant activity]. L'Encephale. PMID 29801770 DOI: 10.1016/j.encep.2018.05.001  0.615
2018 Felice D, Guilloux JP, Pehrson A, Li Y, Mendez-David I, Gardier AM, Sanchez C, David DJ. Vortioxetine Improves Context Discrimination in Mice Through a Neurogenesis Independent Mechanism. Frontiers in Pharmacology. 9: 204. PMID 29593535 DOI: 10.3389/Fphar.2018.00204  0.617
2017 Tritschler L, Kheirbek MA, Dantec YL, Mendez-David I, Guilloux JP, Faye C, Doan J, Pham TH, Hen R, David DJ, Gardier AM. Optogenetic activation of granule cells in the dorsal dentate gyrus enhances dopaminergic neurotransmission in the Nucleus Accumbens. Neuroscience Research. PMID 29246683 DOI: 10.1016/j.neures.2017.12.002  0.628
2017 Mendez-David I, Boursier C, Domergue V, Colle R, Falissard B, Corruble E, Gardier AM, Guilloux JP, David DJ. Differential Peripheral Proteomic Biosignature of Fluoxetine Response in a Mouse Model of Anxiety/Depression. Frontiers in Cellular Neuroscience. 11: 237. PMID 28860968 DOI: 10.3389/fncel.2017.00237  0.668
2017 Mendez-David I, Guilloux JP, Papp M, Tritschler L, Mocaer E, Gardier AM, Bretin S, David DJ. S 47445 Produces Antidepressant- and Anxiolytic-Like Effects through Neurogenesis Dependent and Independent Mechanisms. Frontiers in Pharmacology. 8: 462. PMID 28769796 DOI: 10.3389/fphar.2017.00462  0.675
2017 Mekiri M, Gardier AM, David DJ, Guilloux JP. Chronic Corticosterone Administration Effects on Behavioral Emotionality in Female C57BL6 Mice. Experimental and Clinical Psychopharmacology. PMID 28287792 DOI: 10.1037/Pha0000112  0.765
2017 Guilloux JP, Samuels BA, Mendez-David I, Hu A, Levinstein M, Faye C, Mekiri M, Mocaer E, Gardier AM, Hen R, Sors A, David DJ. S 38093, a histamine H3 antagonist/inverse agonist, promotes hippocampal neurogenesis and improves context discrimination task in aged mice. Scientific Reports. 7: 42946. PMID 28218311 DOI: 10.1038/Srep42946  0.754
2016 Besson M, Guiducci S, Granon S, Guilloux JP, Guiard B, Repérant C, Faure P, Pons S, Cannazza G, Zoli M, Gardier AM, Maskos U. Alterations in alpha5* nicotinic acetylcholine receptors result in midbrain- and hippocampus-dependent behavioural and neural impairments. Psychopharmacology. 233: 3297-314. PMID 27385416 DOI: 10.1007/S00213-016-4362-2  0.647
2016 Darcet F, Gardier AM, Gaillard R, David DJ, Guilloux JP. Cognitive Dysfunction in Major Depressive Disorder. A Translational Review in Animal Models of the Disease. Pharmaceuticals (Basel, Switzerland). 9. PMID 26901205 DOI: 10.3390/Ph9010009  0.768
2016 David DJ, Tritschler L, Guilloux JP, Gardier AM, Sanchez C, Gaillard R. [Pharmacological properties of vortioxetine and its pre-clinical consequences]. L'Encephale. 42: 1S12-23. PMID 26879252 DOI: 10.1016/S0013-7006(16)30015-X  0.643
2016 Darcet F, Gardier AM, David DJ, Guilloux JP. Chronic 5-HT4 receptor agonist treatment restores learning and memory deficits in a neuroendocrine mouse model of anxiety/depression. Neuroscience Letters. 616: 197-203. PMID 26850572 DOI: 10.1016/J.Neulet.2016.01.055  0.795
2016 Qesseveur G, Petit AC, Nguyen HT, Dahan L, Colle R, Rotenberg S, Seif I, Robert P, David D, Guilloux JP, Gardier AM, Verstuyft C, Becquemont L, Corruble E, Guiard BP. Genetic dysfunction of serotonin 2A receptor hampers response to antidepressant drugs: A translational approach. Neuropharmacology. 105: 142-53. PMID 26764241 DOI: 10.1016/J.Neuropharm.2015.12.022  0.796
2016 Siopi E, Denizet M, Gabellec MM, de Chaumont F, Olivo-Marin JC, Guilloux JP, Lledo PM, Lazarini F. Anxiety- and Depression-Like States Lead to Pronounced Olfactory Deficits and Impaired Adult Neurogenesis in Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 518-31. PMID 26758842 DOI: 10.1523/JNEUROSCI.2817-15.2016  0.365
2015 Ding Y, Chang LC, Wang X, Guilloux JP, Parrish J, Oh H, French BJ, Lewis DA, Tseng GC, Sibille E. Molecular and Genetic Characterization of Depression: Overlap with other Psychiatric Disorders and Aging. Molecular Neuropsychiatry. 1: 1-12. PMID 26213687  0.56
2015 Colle R, Gressier F, Verstuyft C, Deflesselle E, Lépine JP, Ferreri F, Hardy P, Guilloux JP, Petit AC, Fève B, Falissard B, Becquemont L, Corruble E. Brain-derived neurotrophic factor Val66Met polymorphism and 6-month antidepressant remission in depressed Caucasian patients. Journal of Affective Disorders. 175: 233-40. PMID 25658497 DOI: 10.1016/j.jad.2015.01.013  0.391
2015 Guilloux JP, Bassi S, Ding Y, Walsh C, Turecki G, Tseng G, Cyranowski JM, Sibille E. Testing the predictive value of peripheral gene expression for nonremission following citalopram treatment for major depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 701-10. PMID 25176167 DOI: 10.1038/Npp.2014.226  0.604
2015 Mendez-David I, David DJ, Guilloux JP, Hen R, Gardier AM. 5-ht4 receptor subtype, β-arrestin level, and rapid-onset effects of antidepressant drugs Neuromethods. 95: 101-121. DOI: 10.1007/978-1-4939-2187-4_6  0.654
2014 Tritschler L, Felice D, Colle R, Guilloux JP, Corruble E, Gardier AM, David DJ. Vortioxetine for the treatment of major depressive disorder. Expert Review of Clinical Pharmacology. 7: 731-45. PMID 25166025 DOI: 10.1586/17512433.2014.950655  0.685
2014 Le Dantec Y, Hache G, Guilloux JP, Guiard BP, David DJ, Adrien J, Escourrou P. NREM sleep hypersomnia and reduced sleep/wake continuity in a neuroendocrine mouse model of anxiety/depression based on chronic corticosterone administration. Neuroscience. 274: 357-68. PMID 24909899 DOI: 10.1016/J.Neuroscience.2014.05.050  0.485
2014 Darcet F, Mendez-David I, Tritschler L, Gardier AM, Guilloux JP, David DJ. Learning and memory impairments in a neuroendocrine mouse model of anxiety/depression. Frontiers in Behavioral Neuroscience. 8: 136. PMID 24822041 DOI: 10.3389/Fnbeh.2014.00136  0.789
2013 Guilloux JP, Mendez-David I, Pehrson A, Guiard BP, Repérant C, Orvoën S, Gardier AM, Hen R, Ebert B, Miller S, Sanchez C, David DJ. Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice. Neuropharmacology. 73: 147-59. PMID 23721744 DOI: 10.1016/J.Neuropharm.2013.05.014  0.77
2013 Douillard-Guilloux G, Guilloux JP, Lewis DA, Sibille E. Anticipated brain molecular aging in major depression. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 21: 450-60. PMID 23570888 DOI: 10.1016/J.Jagp.2013.01.040  0.573
2012 Tripp A, Oh H, Guilloux JP, Martinowich K, Lewis DA, Sibille E. Brain-derived neurotrophic factor signaling and subgenual anterior cingulate cortex dysfunction in major depressive disorder. The American Journal of Psychiatry. 169: 1194-202. PMID 23128924 DOI: 10.1176/Appi.Ajp.2012.12020248  0.59
2012 Xia L, Deloménie C, David I, Rainer Q, Marouard M, Delacroix H, David DJ, Gardier AM, Guilloux JP. Ventral hippocampal molecular pathways and impaired neurogenesis associated with 5-HT₁A and 5-HT₁B receptors disruption in mice. Neuroscience Letters. 521: 20-5. PMID 22622174 DOI: 10.1016/J.Neulet.2012.05.046  0.743
2012 Guilloux JP, Douillard-Guilloux G, Kota R, Wang X, Gardier AM, Martinowich K, Tseng GC, Lewis DA, Sibille E. Molecular evidence for BDNF- and GABA-related dysfunctions in the amygdala of female subjects with major depression. Molecular Psychiatry. 17: 1130-42. PMID 21912391 DOI: 10.1038/Mp.2011.113  0.728
2012 Besson M, David V, Baudonnat M, Cazala P, Guilloux JP, Reperant C, Cloez-Tayarani I, Changeux JP, Gardier AM, Granon S. Alpha7-nicotinic receptors modulate nicotine-induced reinforcement and extracellular dopamine outflow in the mesolimbic system in mice. Psychopharmacology. 220: 1-14. PMID 21901321 DOI: 10.1007/S00213-011-2422-1  0.57
2012 Rainer Q, Xia L, Guilloux JP, Gabriel C, Mocaër E, Hen R, Enhamre E, Gardier AM, David DJ. Beneficial behavioural and neurogenic effects of agomelatine in a model of depression/anxiety. The International Journal of Neuropsychopharmacology. 15: 321-35. PMID 21473810 DOI: 10.1017/S1461145711000356  0.797
2011 Guilloux JP, David DJ, Xia L, Nguyen HT, Rainer Q, Guiard BP, Repérant C, Deltheil T, Toth M, Hen R, Gardier AM. Characterization of 5-HT(1A/1B)-/- mice: an animal model sensitive to anxiolytic treatments. Neuropharmacology. 61: 478-88. PMID 21333660 DOI: 10.1016/J.Neuropharm.2011.02.009  0.792
2011 Guilloux JP, Seney M, Edgar N, Sibille E. Integrated behavioral z-scoring increases the sensitivity and reliability of behavioral phenotyping in mice: relevance to emotionality and sex. Journal of Neuroscience Methods. 197: 21-31. PMID 21277897 DOI: 10.1016/J.Jneumeth.2011.01.019  0.791
2010 Gaiteri C, Guilloux JP, Lewis DA, Sibille E. Altered gene synchrony suggests a combined hormone-mediated dysregulated state in major depression. Plos One. 5: e9970. PMID 20376317 DOI: 10.1371/Journal.Pone.0009970  0.749
2010 Guilloux JP, Gaiteri C, Sibille E. Network analysis of positional candidate genes of schizophrenia highlights...more than... myelin-related pathways. Molecular Psychiatry. 15: 786-8. PMID 20351722 DOI: 10.1038/mp.2009.68  0.671
2010 Popa D, Cerdan J, Repérant C, Guiard BP, Guilloux JP, David DJ, Gardier AM. A longitudinal study of 5-HT outflow during chronic fluoxetine treatment using a new technique of chronic microdialysis in a highly emotional mouse strain. European Journal of Pharmacology. 628: 83-90. PMID 19944680 DOI: 10.1016/j.ejphar.2009.11.037  0.735
2010 Rainer Q, Gabriel C, Mocaer E, Xia L, Hen R, Enhamre E, Guilloux J, Gardier A, David D. P01-74 - Beneficial effects of chronic treatment with agomelatine on the anxiety-and depression-like state induced by corticosterone in C57BL/6NTAC mice European Psychiatry. 25: 295. DOI: 10.1016/S0924-9338(10)70293-5  0.799
2009 David DJ, Samuels BA, Rainer Q, Wang JW, Marsteller D, Mendez I, Drew M, Craig DA, Guiard BP, Guilloux JP, Artymyshyn RP, Gardier AM, Gerald C, Antonijevic IA, Leonardo ED, et al. Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression. Neuron. 62: 479-93. PMID 19477151 DOI: 10.1016/J.Neuron.2009.04.017  0.778
2009 Gardier AM, Guiard BP, Guilloux JP, Repérant C, Coudoré F, David DJ. Interest of using genetically manipulated mice as models of depression to evaluate antidepressant drugs activity: a review. Fundamental & Clinical Pharmacology. 23: 23-42. PMID 19267769 DOI: 10.1111/j.1472-8206.2008.00640.x  0.764
2008 Deltheil T, Guiard BP, Cerdan J, David DJ, Tanaka KF, Repérant C, Guilloux JP, Coudoré F, Hen R, Gardier AM. Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice. Neuropharmacology. 55: 1006-14. PMID 18761360 DOI: 10.1016/j.neuropharm.2008.08.001  0.776
2008 Deltheil T, Guiard BP, Guilloux JP, Nicolas L, Deloménie C, Repérant C, Le Maitre E, Leroux-Nicollet I, Benmansour S, Coudoré F, David DJ, Gardier AM. Consequences of changes in BDNF levels on serotonin neurotransmission, 5-HT transporter expression and function: studies in adult mice hippocampus. Pharmacology, Biochemistry, and Behavior. 90: 174-83. PMID 17980409 DOI: 10.1016/j.pbb.2007.09.018  0.715
2007 Guiard BP, Guilloux JP, Reperant C, Hunt SP, Toth M, Gardier AM. Substance P neurokinin 1 receptor activation within the dorsal raphe nucleus controls serotonin release in the mouse frontal cortex. Molecular Pharmacology. 72: 1411-8. PMID 17890358 DOI: 10.1124/mol.107.040113  0.74
2006 Molles BE, Maskos U, Pons S, Besson M, Guiard P, Guilloux JP, Evrard A, Cormier A, Mameli-Engvall M, Cloëz-Tayarani I, Nakatani H, Dufour N, Bemelmans AP, Mallet J, Cazala P, et al. Targeted in vivo expression of nicotinic acetylcholine receptors in mouse brain using lentiviral expression vectors. Journal of Molecular Neuroscience : Mn. 30: 105-6. PMID 17192649 DOI: 10.1385/JMN:30:1:105  0.55
2006 Guilloux JP, David DJ, Guiard BP, Chenu F, Repérant C, Toth M, Bourin M, Gardier AM. Blockade of 5-HT1A receptors by (+/-)-pindolol potentiates cortical 5-HT outflow, but not antidepressant-like activity of paroxetine: microdialysis and behavioral approaches in 5-HT1A receptor knockout mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2162-72. PMID 16452992 DOI: 10.1038/sj.npp.1301019  0.752
2005 Maskos U, Molles BE, Pons S, Besson M, Guiard BP, Guilloux JP, Evrard A, Cazala P, Cormier A, Mameli-Engvall M, Dufour N, Cloëz-Tayarani I, Bemelmans AP, Mallet J, Gardier AM, et al. Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors. Nature. 436: 103-7. PMID 16001069 DOI: 10.1038/Nature03694  0.669
2004 Bert L, Favale D, Jego G, Greve P, Guilloux JP, Guiard BP, Gardier AM, Suaud-Chagny MF, Lestage P. Rapid and precise method to locate microdialysis probe implantation in the rodent brain. Journal of Neuroscience Methods. 140: 53-7. PMID 15589334 DOI: 10.1016/j.jneumeth.2004.04.042  0.632
2004 Guiard BP, Przybylski C, Guilloux JP, Seif I, Froger N, De Felipe C, Hunt SP, Lanfumey L, Gardier AM. Blockade of substance P (neurokinin 1) receptors enhances extracellular serotonin when combined with a selective serotonin reuptake inhibitor: an in vivo microdialysis study in mice. Journal of Neurochemistry. 89: 54-63. PMID 15030389 DOI: 10.1046/j.1471-4159.2003.02304.x  0.724
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