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René Hen - Publications

Affiliations: 
Columbia University, New York, NY 
Area:
Serotonin
Website:
http://www.neuroscience.columbia.edu/index.php?page=28&bio=82

310 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Boldrini M, Galfalvy H, Dwork AJ, Rosoklija GB, Trencevska-Ivanovska I, Pavlovski G, Hen R, Arango V, Mann JJ. Resilience Is Associated With Larger Dentate Gyrus, While Suicide Decedents With Major Depressive Disorder Have Fewer Granule Neurons. Biological Psychiatry. PMID 30819514 DOI: 10.1016/j.biopsych.2018.12.022  0.68
2019 Cunningham AM, Santos TL, Gutzeit VA, Hamilton H, Hen R, Donaldson Z. Functional interrogation of a depression-related serotonergic SNP, rs6295, using a humanized mouse model. Acs Chemical Neuroscience. PMID 30694044 DOI: 10.1021/acschemneuro.8b00638  0.52
2018 Turcotte-Cardin V, Vahid-Ansari F, Luckhart C, Daigle M, Geddes SD, Tanaka KF, Hen R, James J, Merali Z, Béïque JC, Albert PR. Loss of adult 5-HT1A autoreceptors results in a paradoxical anxiogenic response to antidepressant treatment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30552180 DOI: 10.1523/JNEUROSCI.0352-18.2018  1
2018 Tartt AN, Fulmore CA, Liu Y, Rosoklija GB, Dwork AJ, Arango V, Hen R, Mann JJ, Boldrini M. Considerations for Assessing the Extent of Hippocampal Neurogenesis in the Adult and Aging Human Brain. Cell Stem Cell. 23: 782-783. PMID 30526880 DOI: 10.1016/j.stem.2018.10.025  0.68
2018 Anacker C, Luna VM, Stevens GS, Millette A, Shores R, Jimenez JC, Chen B, Hen R. Hippocampal neurogenesis confers stress resilience by inhibiting the ventral dentate gyrus. Nature. PMID 29950730 DOI: 10.1038/s41586-018-0262-4  1
2018 Besnard A, Langberg T, Levinson S, Chu D, Vicidomini C, Scobie KN, Dwork AJ, Arango V, Rosoklija GB, Mann JJ, Hen R, Leonardo ED, Boldrini M, Sahay A. Targeting Kruppel-like Factor 9 in Excitatory Neurons Protects against Chronic Stress-Induced Impairments in Dendritic Spines and Fear Responses. Cell Reports. 23: 3183-3196. PMID 29898391 DOI: 10.1016/j.celrep.2018.05.040  1
2018 Pavlova IP, Shipley SC, Lanio M, Hen R, Denny CA. Optimization of immunolabeling and clearing techniques for indelibly-labeled memory traces. Hippocampus. PMID 29663578 DOI: 10.1002/hipo.22951  1
2018 Philippe TJ, Vahid-Ansari F, Donaldson ZR, Le François B, Zahrai A, Turcotte-Cardin V, Daigle M, James J, Hen R, Merali Z, Albert PR. Loss of MeCP2 in adult 5-HT neurons induces 5-HT1A autoreceptors, with opposite sex-dependent anxiety and depression phenotypes. Scientific Reports. 8: 5788. PMID 29636529 DOI: 10.1038/s41598-018-24167-8  1
2018 Boldrini M, Fulmore CA, Tartt AN, Simeon LR, Pavlova I, Poposka V, Rosoklija GB, Stankov A, Arango V, Dwork AJ, Hen R, Mann JJ. Human Hippocampal Neurogenesis Persists throughout Aging. Cell Stem Cell. 22: 589-599.e5. PMID 29625071 DOI: 10.1016/j.stem.2018.03.015  0.68
2018 Zhou P, Resendez SL, Rodriguez-Romaguera J, Jimenez JC, Neufeld SQ, Giovannucci A, Friedrich J, Pnevmatikakis EA, Stuber GD, Hen R, Kheirbek MA, Sabatini BL, Kass RE, Paninski L. Efficient and accurate extraction ofcalcium signals from microendoscopic video data. Elife. 7. PMID 29469809 DOI: 10.7554/eLife.28728  1
2018 Jimenez JC, Su K, Goldberg AR, Luna VM, Biane JS, Ordek G, Zhou P, Ong SK, Wright MA, Zweifel L, Paninski L, Hen R, Kheirbek MA. Anxiety Cells in a Hippocampal-Hypothalamic Circuit. Neuron. PMID 29397273 DOI: 10.1016/j.neuron.2018.01.016  1
2017 Tritschler L, Kheirbek MA, Dantec YL, Mendez-David I, Guilloux JP, Faye C, Doan J, Pham TH, Hen R, David DJ, Gardier AM. Optogenetic activation of granule cells in the dorsal dentate gyrus enhances dopaminergic neurotransmission in the Nucleus Accumbens. Neuroscience Research. PMID 29246683 DOI: 10.1016/j.neures.2017.12.002  1
2017 Vahid-Ansari F, Daigle M, Manzini MC, Tanaka KF, Hen R, Geddes SD, Béïque JC, James J, Merali Z, Albert PR. Abrogated Freud-1/CC2D1A repression of 5-HT1A autoreceptors induces fluoxetine-resistant anxiety/depression-like behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29101244 DOI: 10.1523/JNEUROSCI.1668-17.2017  1
2017 Harris AZ, Atsak P, Bretton ZH, Holt ES, Alam R, Morton MP, Abbas AI, Leonardo ED, Bolkan SS, Hen R, Gordon JA. A Novel Method for Chronic Social Defeat Stress in Female Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29090682 DOI: 10.1038/npp.2017.259  0.96
2017 Culig L, Surget A, Bourdey M, Khemissi W, Le Guisquet AM, Vogel E, Sahay A, Hen R, Belzung C. Increasing adult hippocampal neurogenesis in mice after exposure to unpredictable chronic mild stress may counteract some of the effects of stress. Neuropharmacology. PMID 28890366 DOI: 10.1016/j.neuropharm.2017.09.009  1
2017 Nautiyal KM, Okuda M, Hen R, Blanco C. Gambling disorder: an integrative review of animal and human studies. Annals of the New York Academy of Sciences. 1394: 106-127. PMID 28486792 DOI: 10.1111/nyas.13356  1
2017 Anacker C, Hen R. Adult hippocampal neurogenesis and cognitive flexibility - linking memory and mood. Nature Reviews. Neuroscience. PMID 28469276 DOI: 10.1038/nrn.2017.45  1
2017 Chen WV, Nwakeze CL, Denny CA, O'Keeffe S, Rieger MA, Mountoufaris G, Kirner A, Dougherty JD, Hen R, Wu Q, Maniatis T. Pcdhαc2 is required for axonal tiling and assembly of serotonergic circuitries in mice. Science (New York, N.Y.). 356: 406-411. PMID 28450636 DOI: 10.1126/science.aal3231  1
2017 Samuels BA, Nautiyal KM, Kruegel AC, Levinstein MR, Magalong VM, Gassaway MM, Grinnell SG, Han J, Ansonoff MA, Pintar JE, Javitch JA, Sames D, Hen R. The Behavioral Effects of the Antidepressant Tianeptine Require the Mu Opioid Receptor. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28303899 DOI: 10.1038/npp.2017.60  1
2017 Nautiyal KM, Hen R. Serotonin receptors in depression: from A to B. F1000research. 6: 123. PMID 28232871 DOI: 10.12688/f1000research.9736.1  1
2017 Guilloux JP, Samuels BA, Mendez-David I, Hu A, Levinstein M, Faye C, Mekiri M, Mocaer E, Gardier AM, Hen R, Sors A, David DJ. S 38093, a histamine H3 antagonist/inverse agonist, promotes hippocampal neurogenesis and improves context discrimination task in aged mice. Scientific Reports. 7: 42946. PMID 28218311 DOI: 10.1038/srep42946  1
2016 Nautiyal KM, Wall MM, Wang S, Magalong VM, Ahmari SE, Balsam PD, Blanco C, Hen R. Genetic and Modelling Approaches Reveal Distinct Components of Impulsive Behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27976680 DOI: 10.1038/npp.2016.277  1
2016 McAvoy KM, Scobie KN, Berger S, Russo C, Guo N, Decharatanachart P, Vega-Ramirez H, Miake-Lye S, Whalen M, Nelson M, Bergami M, Bartsch D, Hen R, Berninger B, Sahay A. Modulating Neuronal Competition Dynamics in the Dentate Gyrus to Rejuvenate Aging Memory Circuits. Neuron. 91: 1356-73. PMID 27593178 DOI: 10.1016/j.neuron.2016.08.009  1
2016 Nautiyal KM, Tritschler L, Ahmari SE, David DJ, Gardier AM, Hen R. A Lack of Serotonin 1B Autoreceptors Results in Decreased Anxiety and Depression-Related Behaviors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 41: 2941-2950. PMID 27353308 DOI: 10.1038/npp.2016.109  1
2016 Tannenholz L, Hen R, Kheirbek MA. GluN2B-Containg NMDA Receptors on Adult-Born Granule Cells Contribute to the Antidepressant Action of Fluoxetine. Frontiers in Neuroscience. 10: 242. PMID 27303260 DOI: 10.3389/fnins.2016.00242  1
2016 Danielson NB, Kaifosh P, Zaremba JD, Lovett-Barron M, Tsai J, Denny CA, Balough EM, Goldberg AR, Drew LJ, Hen R, Losonczy A, Kheirbek MA. Distinct Contribution of Adult-Born Hippocampal Granule Cells to Context Encoding. Neuron. 90: 101-12. PMID 26971949 DOI: 10.1016/j.neuron.2016.02.019  1
2016 Donaldson ZR, le Francois B, Santos TL, Almli LM, Boldrini M, Champagne FA, Arango V, Mann JJ, Stockmeier CA, Galfalvy H, Albert PR, Ressler KJ, Hen R. The functional serotonin 1a receptor promoter polymorphism, rs6295, is associated with psychiatric illness and differences in transcription. Translational Psychiatry. 6: e746. PMID 26926882 DOI: 10.1038/tp.2015.226  1
2016 Drew LJ, Kheirbek MA, Luna VM, Denny CA, Cloidt MA, Wu MV, Jain S, Scharfman HE, Hen R. Activation of local inhibitory circuits in the dentate gyrus by adult-born neurons. Hippocampus. 26: 763-78. PMID 26662922 DOI: 10.1002/hipo.22557  1
2016 Satała G, Duszyńska B, Stachowicz K, Rafalo A, Pochwat B, Luckhart C, Albert PR, Daigle M, Tanaka KF, Hen R, Lenda T, Nowak G, Bojarski AJ, Szewczyk B. Concentration-Dependent Dual Mode of Zn Action at Serotonin 5-HT1A Receptors: In Vitro and In Vivo Studies. Molecular Neurobiology. 53: 6869-6881. PMID 26660328 DOI: 10.1007/s12035-015-9586-3  1
2016 Anacker C, Scholz J, O'Donnell KJ, Allemang-Grand R, Diorio J, Bagot RC, Nestler EJ, Hen R, Lerch JP, Meaney MJ. Neuroanatomic Differences Associated With Stress Susceptibility and Resilience. Biological Psychiatry. 79: 840-9. PMID 26422005 DOI: 10.1016/j.biopsych.2015.08.009  1
2016 Brachman RA, McGowan JC, Perusini JN, Lim SC, Pham TH, Faye C, Gardier AM, Mendez-David I, David DJ, Hen R, Denny CA. Ketamine as a Prophylactic Against Stress-Induced Depressive-like Behavior. Biological Psychiatry. 79: 776-86. PMID 26037911 DOI: 10.1016/j.biopsych.2015.04.022  1
2016 Samuels BA, Mendez-David I, Faye C, David SA, Pierz KA, Gardier AM, Hen R, David DJ. Serotonin 1A and Serotonin 4 Receptors: Essential Mediators of the Neurogenic and Behavioral Actions of Antidepressants. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 22: 26-45. PMID 25488850 DOI: 10.1177/1073858414561303  1
2015 Anacker C, Denny CA, Hen R. Regulation of hippocampal memory traces by neurogenesis. Neurogenesis (Austin, Tex.). 2: e1025180. PMID 27604158 DOI: 10.1080/23262133.2015.1025180  1
2015 Mingote S, Masson J, Gellman C, Thomsen GM, Lin CS, Merker RJ, Gaisler-Salomon I, Wang Y, Ernst R, Hen R, Rayport S. Genetic Pharmacotherapy as an Early CNS Drug Development Strategy: Testing Glutaminase Inhibition for Schizophrenia Treatment in Adult Mice. Frontiers in Systems Neuroscience. 9: 165. PMID 26778975 DOI: 10.3389/fnsys.2015.00165  0.32
2015 Samuels BA, Anacker C, Hu A, Levinstein MR, Pickenhagen A, Tsetsenis T, Madroñal N, Donaldson ZR, Drew LJ, Dranovsky A, Gross CT, Tanaka KF, Hen R. 5-HT1A receptors on mature dentate gyrus granule cells are critical for the antidepressant response. Nature Neuroscience. 18: 1606-16. PMID 26389840 DOI: 10.1038/nn.4116  1
2015 Borgkvist A, Avegno EM, Wong MY, Kheirbek MA, Sonders MS, Hen R, Sulzer D. Loss of Striatonigral GABAergic Presynaptic Inhibition Enables Motor Sensitization in Parkinsonian Mice. Neuron. 87: 976-88. PMID 26335644 DOI: 10.1016/j.neuron.2015.08.022  1
2015 Wu MV, Luna VM, Hen R. Running rescues a fear-based contextual discrimination deficit in aged mice. Frontiers in Systems Neuroscience. 9: 114. PMID 26321926 DOI: 10.3389/fnsys.2015.00114  0.6
2015 Park EH, Burghardt NS, Dvorak D, Hen R, Fenton AA. Experience-Dependent Regulation of Dentate Gyrus Excitability by Adult-Born Granule Cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 11656-66. PMID 26290242 DOI: 10.1523/JNEUROSCI.0885-15.2015  0.56
2015 Wu MV, Sahay A, Duman RS, Hen R. Functional differentiation of adult-born neurons along the septotemporal axis of the dentate gyrus. Cold Spring Harbor Perspectives in Biology. 7: a018978. PMID 26238355 DOI: 10.1101/cshperspect.a018978  1
2015 Nautiyal KM, Tanaka KF, Barr MM, Tritschler L, Le Dantec Y, David DJ, Gardier AM, Blanco C, Hen R, Ahmari SE. Distinct Circuits Underlie the Effects of 5-HT1B Receptors on Aggression and Impulsivity. Neuron. 86: 813-26. PMID 25892302 DOI: 10.1016/j.neuron.2015.03.041  1
2015 Hill AS, Sahay A, Hen R. Increasing Adult Hippocampal Neurogenesis is Sufficient to Reduce Anxiety and Depression-Like Behaviors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 2368-78. PMID 25833129 DOI: 10.1038/npp.2015.85  1
2015 Samuels BA, Leonardo ED, Hen R. Hippocampal subfields and major depressive disorder. Biological Psychiatry. 77: 210-1. PMID 25542516 DOI: 10.1016/j.biopsych.2014.11.007  1
2015 Iyengar SS, LaFrancois JJ, Friedman D, Drew LJ, Denny CA, Burghardt NS, Wu MV, Hsieh J, Hen R, Scharfman HE. Suppression of adult neurogenesis increases the acute effects of kainic acid. Experimental Neurology. 264: 135-49. PMID 25476494 DOI: 10.1016/j.expneurol.2014.11.009  1
2015 Donaldson ZR, Hen R. From psychiatric disorders to animal models: a bidirectional and dimensional approach. Biological Psychiatry. 77: 15-21. PMID 24650688 DOI: 10.1016/j.biopsych.2014.02.004  1
2015 Wu MV, Luna VM, Hen R. Running rescues a fear-based contextual discrimination deficit in aged mice Frontiers in Systems Neuroscience. 9. DOI: 10.3389/fnsys.2015.00114  1
2015 Park EH, Burghardt NS, Dvorak D, Hen R, Fenton AA. Experience-dependent regulation of dentate gyrus excitability by adult-born granule cells Journal of Neuroscience. 35: 11656-11666. DOI: 10.1523/JNEUROSCI.0885-15.2015  1
2015 Borgkvist A, Avegno EM, Wong MY, Kheirbek MA, Sonders MS, Hen R, Sulzer D. Loss of Striatonigral GABAergic Presynaptic Inhibition Enables Motor Sensitization in Parkinsonian Mice Neuron. 87: 976-988. DOI: 10.1016/j.neuron.2015.08.022  1
2015 Mendez-David I, David DJ, Guilloux JP, Hen R, Gardier AM. 5-ht4 receptor subtype, β-arrestin level, and rapid-onset effects of antidepressant drugs Neuromethods. 95: 101-121. DOI: 10.1007/978-1-4939-2187-4_6  1
2014 Root CM, Denny CA, Hen R, Axel R. The participation of cortical amygdala in innate, odour-driven behaviour. Nature. 515: 269-73. PMID 25383519 DOI: 10.1038/nature13897  1
2014 Denny CA, Kheirbek MA, Alba EL, Tanaka KF, Brachman RA, Laughman KB, Tomm NK, Turi GF, Losonczy A, Hen R. Hippocampal memory traces are differentially modulated by experience, time, and adult neurogenesis. Neuron. 83: 189-201. PMID 24991962 DOI: 10.1016/j.neuron.2014.05.018  1
2014 Kheirbek MA, Hen R. Add neurons, subtract anxiety. Scientific American. 311: 62-7. PMID 24974712  1
2014 Boldrini M, Butt TH, Santiago AN, Tamir H, Dwork AJ, Rosoklija GB, Arango V, Hen R, Mann JJ. Benzodiazepines and the potential trophic effect of antidepressants on dentate gyrus cells in mood disorders. The International Journal of Neuropsychopharmacology. 17: 1923-33. PMID 24969726 DOI: 10.1017/S1461145714000844  0.68
2014 Lovett-Barron M, Kaifosh P, Kheirbek MA, Danielson N, Zaremba JD, Reardon TR, Turi GF, Hen R, Zemelman BV, Losonczy A. Dendritic inhibition in the hippocampus supports fear learning. Science (New York, N.Y.). 343: 857-63. PMID 24558155 DOI: 10.1126/science.1247485  1
2014 Wu MV, Hen R. Functional dissociation of adult-born neurons along the dorsoventral axis of the dentate gyrus. Hippocampus. 24: 751-61. PMID 24550158 DOI: 10.1002/hipo.22265  0.6
2014 Wu MV, Shamy JL, Bedi G, Choi CW, Wall MM, Arango V, Boldrini M, Foltin RW, Hen R. Impact of social status and antidepressant treatment on neurogenesis in the baboon hippocampus. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1861-71. PMID 24518288 DOI: 10.1038/npp.2014.33  0.68
2014 Samuels BA, Leonardo ED, Dranovsky A, Williams A, Wong E, Nesbitt AM, McCurdy RD, Hen R, Alter M. Global state measures of the dentate gyrus gene expression system predict antidepressant-sensitive behaviors. Plos One. 9: e85136. PMID 24465494 DOI: 10.1371/journal.pone.0085136  1
2014 Mendez-David I, David DJ, Darcet F, Wu MV, Kerdine-Römer S, Gardier AM, Hen R. Rapid anxiolytic effects of a 5-HT₄ receptor agonist are mediated by a neurogenesis-independent mechanism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1366-78. PMID 24287720 DOI: 10.1038/npp.2013.332  1
2014 Donaldson ZR, Piel DA, Santos TL, Richardson-Jones J, Leonardo ED, Beck SG, Champagne FA, Hen R. Developmental effects of serotonin 1A autoreceptors on anxiety and social behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 291-302. PMID 23907404 DOI: 10.1038/npp.2013.185  1
2014 Brachman RA, McGowan JC, Perusini JN, Lim SC, Pham TH, Faye C, Gardier AM, Mendez-David I, David DJ, Hen R, Denny CA. Ketamine as a Prophylactic Against Stress-Induced Depressive-Like Behavior Biological Psychiatry. DOI: 10.1016/j.biopsych.2015.04.022  1
2013 Ikrar T, Guo N, He K, Besnard A, Levinson S, Hill A, Lee HK, Hen R, Xu X, Sahay A. Adult neurogenesis modifies excitability of the dentate gyrus. Frontiers in Neural Circuits. 7: 204. PMID 24421758 DOI: 10.3389/fncir.2013.00204  1
2013 Drew LJ, Fusi S, Hen R. Adult neurogenesis in the mammalian hippocampus: why the dentate gyrus? Learning & Memory (Cold Spring Harbor, N.Y.). 20: 710-29. PMID 24255101 DOI: 10.1101/lm.026542.112  0.72
2013 Mendez-David I, El-Ali Z, Hen R, Falissard B, Corruble E, Gardier AM, Kerdine-Römer S, David DJ. A method for biomarker measurements in peripheral blood mononuclear cells isolated from anxious and depressed mice: β-arrestin 1 protein levels in depression and treatment. Frontiers in Pharmacology. 4: 124. PMID 24133448 DOI: 10.3389/fphar.2013.00124  1
2013 Kheirbek MA, Hen R. (Radio)active neurogenesis in the human hippocampus. Cell. 153: 1183-4. PMID 23746833 DOI: 10.1016/j.cell.2013.05.033  1
2013 Ahmari SE, Spellman T, Douglass NL, Kheirbek MA, Simpson HB, Deisseroth K, Gordon JA, Hen R. Repeated cortico-striatal stimulation generates persistent OCD-like behavior. Science (New York, N.Y.). 340: 1234-9. PMID 23744948 DOI: 10.1126/science.1234733  1
2013 Guilloux JP, Mendez-David I, Pehrson A, Guiard BP, Repérant C, Orvoën S, Gardier AM, Hen R, Ebert B, Miller S, Sanchez C, David DJ. Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice. Neuropharmacology. 73: 147-59. PMID 23721744 DOI: 10.1016/j.neuropharm.2013.05.014  1
2013 Quesseveur G, David DJ, Gaillard MC, Pla P, Wu MV, Nguyen HT, Nicolas V, Auregan G, David I, Dranovsky A, Hantraye P, Hen R, Gardier AM, Déglon N, Guiard BP. BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities. Translational Psychiatry. 3: e253. PMID 23632457 DOI: 10.1038/tp.2013.30  1
2013 Mendez-David I, Hen R, Gardier AM, David DJ. Adult hippocampal neurogenesis: an actor in the antidepressant-like action. Annales Pharmaceutiques Francaises. 71: 143-9. PMID 23622692 DOI: 10.1016/j.pharma.2013.02.006  1
2013 Kheirbek MA, Drew LJ, Burghardt NS, Costantini DO, Tannenholz L, Ahmari SE, Zeng H, Fenton AA, Hen R. Differential control of learning and anxiety along the dorsoventral axis of the dentate gyrus. Neuron. 77: 955-68. PMID 23473324 DOI: 10.1016/j.neuron.2012.12.038  1
2013 Wu MV, Hen R. The young and the restless: regulation of adult neurogenesis by Wnt signaling. Cell Stem Cell. 12: 139-40. PMID 23395437 DOI: 10.1016/j.stem.2013.01.013  0.6
2013 Donaldson ZR, Nautiyal KM, Ahmari SE, Hen R. Genetic approaches for understanding the role of serotonin receptors in mood and behavior. Current Opinion in Neurobiology. 23: 399-406. PMID 23385115 DOI: 10.1016/j.conb.2013.01.011  1
2013 Boldrini M, Santiago AN, Hen R, Dwork AJ, Rosoklija GB, Tamir H, Arango V, John Mann J. Hippocampal granule neuron number and dentate gyrus volume in antidepressant-treated and untreated major depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1068-77. PMID 23303074 DOI: 10.1038/npp.2013.5  0.68
2013 Jang MH, Kitabatake Y, Kang E, Jun H, Pletnikov MV, Christian KM, Hen R, Lucae S, Binder EB, Song H, Ming GI. Secreted frizzled-related protein 3 (sFRP3) regulates antidepressant responses in mice and humans. Molecular Psychiatry. 18: 957-8. PMID 23207650 DOI: 10.1038/mp.2012.158  1
2012 Kheirbek MA, Klemenhagen KC, Sahay A, Hen R. Neurogenesis and generalization: a new approach to stratify and treat anxiety disorders. Nature Neuroscience. 15: 1613-20. PMID 23187693 DOI: 10.1038/nn.3262  1
2012 Baudouin SJ, Gaudias J, Gerharz S, Hatstatt L, Zhou K, Punnakkal P, Tanaka KF, Spooren W, Hen R, De Zeeuw CI, Vogt K, Scheiffele P. Shared synaptic pathophysiology in syndromic and nonsyndromic rodent models of autism. Science (New York, N.Y.). 338: 128-32. PMID 22983708 DOI: 10.1126/science.1224159  1
2012 Kode A, Mosialou I, Silva BC, Rached MT, Zhou B, Wang J, Townes TM, Hen R, DePinho RA, Guo XE, Kousteni S. FOXO1 orchestrates the bone-suppressing function of gut-derived serotonin. The Journal of Clinical Investigation. 122: 3490-503. PMID 22945629 DOI: 10.1172/JCI64906  0.68
2012 Tanaka KF, Matsui K, Sasaki T, Sano H, Sugio S, Fan K, Hen R, Nakai J, Yanagawa Y, Hasuwa H, Okabe M, Deisseroth K, Ikenaka K, Yamanaka A. Expanding the repertoire of optogenetically targeted cells with an enhanced gene expression system. Cell Reports. 2: 397-406. PMID 22854021 DOI: 10.1016/j.celrep.2012.06.011  1
2012 Tanaka KF, Samuels BA, Hen R. Serotonin receptor expression along the dorsal-ventral axis of mouse hippocampus. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 367: 2395-401. PMID 22826340 DOI: 10.1098/rstb.2012.0038  1
2012 Kheirbek MA, Tannenholz L, Hen R. NR2B-dependent plasticity of adult-born granule cells is necessary for context discrimination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8696-702. PMID 22723709 DOI: 10.1523/JNEUROSCI.1692-12.2012  1
2012 Boldrini M, Hen R, Underwood MD, Rosoklija GB, Dwork AJ, Mann JJ, Arango V. Hippocampal angiogenesis and progenitor cell proliferation are increased with antidepressant use in major depression. Biological Psychiatry. 72: 562-71. PMID 22652019 DOI: 10.1016/j.biopsych.2012.04.024  0.68
2012 Glinka ME, Samuels BA, Diodato A, Teillon J, Feng Mei D, Shykind BM, Hen R, Fleischmann A. Olfactory deficits cause anxiety-like behaviors in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6718-25. PMID 22573694 DOI: 10.1523/JNEUROSCI.4287-11.2012  1
2012 Burghardt NS, Park EH, Hen R, Fenton AA. Adult-born hippocampal neurons promote cognitive flexibility in mice. Hippocampus. 22: 1795-808. PMID 22431384 DOI: 10.1002/hipo.22013  0.56
2012 Gire DH, Franks KM, Zak JD, Tanaka KF, Whitesell JD, Mulligan AA, Hen R, Schoppa NE. Mitral cells in the olfactory bulb are mainly excited through a multistep signaling path. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 2964-75. PMID 22378870 DOI: 10.1523/JNEUROSCI.5580-11.2012  1
2012 Denny CA, Burghardt NS, Schachter DM, Hen R, Drew MR. 4- to 6-week-old adult-born hippocampal neurons influence novelty-evoked exploration and contextual fear conditioning. Hippocampus. 22: 1188-201. PMID 21739523 DOI: 10.1002/hipo.20964  1
2012 Arias A, Lamé MW, Santarelli L, Hen R, Greene LA, Angelastro JM. Regulated ATF5 loss-of-function in adult mice blocks formation and causes regression/eradication of gliomas. Oncogene. 31: 739-51. PMID 21725368 DOI: 10.1038/onc.2011.276  1
2012 Rainer Q, Xia L, Guilloux JP, Gabriel C, Mocaër E, Hen R, Enhamre E, Gardier AM, David DJ. Beneficial behavioural and neurogenic effects of agomelatine in a model of depression/anxiety. The International Journal of Neuropsychopharmacology. 15: 321-35. PMID 21473810 DOI: 10.1017/S1461145711000356  1
2012 Lacefield CO, Itskov V, Reardon T, Hen R, Gordon JA. Effects of adult-generated granule cells on coordinated network activity in the dentate gyrus. Hippocampus. 22: 106-16. PMID 20882540 DOI: 10.1002/hipo.20860  0.96
2011 Drew LJ, Hen R. Food for thought: linking caloric intake to behavior via sirtuin activity. Cell. 147: 1436-7. PMID 22196720 DOI: 10.1016/j.cell.2011.11.052  0.72
2011 Karpova NN, Pickenhagen A, Lindholm J, Tiraboschi E, Kulesskaya N, Agústsdóttir A, Antila H, Popova D, Akamine Y, Bahi A, Sullivan R, Hen R, Drew LJ, Castrén E. Fear erasure in mice requires synergy between antidepressant drugs and extinction training. Science (New York, N.Y.). 334: 1731-4. PMID 22194582 DOI: 10.1126/science.1214592  0.72
2011 Dranovsky A, Picchini AM, Moadel T, Sisti AC, Yamada A, Kimura S, Leonardo ED, Hen R. Experience dictates stem cell fate in the adult hippocampus. Neuron. 70: 908-23. PMID 21658584 DOI: 10.1016/j.neuron.2011.05.022  0.88
2011 Sahay A, Wilson DA, Hen R. Pattern separation: a common function for new neurons in hippocampus and olfactory bulb. Neuron. 70: 582-8. PMID 21609817 DOI: 10.1016/j.neuron.2011.05.012  1
2011 Surget A, Tanti A, Leonardo ED, Laugeray A, Rainer Q, Touma C, Palme R, Griebel G, Ibarguen-Vargas Y, Hen R, Belzung C. Antidepressants recruit new neurons to improve stress response regulation. Molecular Psychiatry. 16: 1177-88. PMID 21537331 DOI: 10.1038/mp.2011.48  1
2011 Perera TD, Dwork AJ, Keegan KA, Thirumangalakudi L, Lipira CM, Joyce N, Lange C, Higley JD, Rosoklija G, Hen R, Sackeim HA, Coplan JD. Necessity of hippocampal neurogenesis for the therapeutic action of antidepressants in adult nonhuman primates. Plos One. 6: e17600. PMID 21525974 DOI: 10.1371/journal.pone.0017600  0.68
2011 Richardson-Jones JW, Craige CP, Nguyen TH, Kung HF, Gardier AM, Dranovsky A, David DJ, Guiard BP, Beck SG, Hen R, Leonardo ED. Serotonin-1A autoreceptors are necessary and sufficient for the normal formation of circuits underlying innate anxiety. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6008-18. PMID 21508226 DOI: 10.1523/JNEUROSCI.5836-10.2011  1
2011 Sahay A, Scobie KN, Hill AS, O'Carroll CM, Kheirbek MA, Burghardt NS, Fenton AA, Dranovsky A, Hen R. Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation. Nature. 472: 466-70. PMID 21460835 DOI: 10.1038/nature09817  1
2011 Samuels BA, Hen R. Neurogenesis and affective disorders. The European Journal of Neuroscience. 33: 1152-9. PMID 21395859 DOI: 10.1111/j.1460-9568.2011.07614.x  1
2011 Alter MD, Kharkar R, Ramsey KE, Craig DW, Melmed RD, Grebe TA, Bay RC, Ober-Reynolds S, Kirwan J, Jones JJ, Turner JB, Hen R, Stephan DA. Autism and increased paternal age related changes in global levels of gene expression regulation. Plos One. 6: e16715. PMID 21379579 DOI: 10.1371/journal.pone.0016715  0.36
2011 Samuels BA, Leonardo ED, Gadient R, Williams A, Zhou J, David DJ, Gardier AM, Wong EH, Hen R. Modeling treatment-resistant depression. Neuropharmacology. 61: 408-13. PMID 21356220 DOI: 10.1016/j.neuropharm.2011.02.017  1
2011 Guilloux JP, David DJ, Xia L, Nguyen HT, Rainer Q, Guiard BP, Repérant C, Deltheil T, Toth M, Hen R, Gardier AM. Characterization of 5-HT(1A/1B)-/- mice: an animal model sensitive to anxiolytic treatments. Neuropharmacology. 61: 478-88. PMID 21333660 DOI: 10.1016/j.neuropharm.2011.02.009  1
2011 Weber T, Baier V, Pauly R, Sahay A, Baur M, Herrmann E, Ciccolini F, Hen R, Kronenberg G, Bartsch D. Inducible gene expression in GFAP+ progenitor cells of the SGZ and the dorsal wall of the SVZ-A novel tool to manipulate and trace adult neurogenesis. Glia. 59: 615-26. PMID 21294160 DOI: 10.1002/glia.21129  1
2011 Chuhma N, Tanaka KF, Hen R, Rayport S. Functional connectome of the striatal medium spiny neuron. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 1183-92. PMID 21273403 DOI: 10.1523/JNEUROSCI.3833-10.2011  1
2011 Yadav VK, Oury F, Tanaka KF, Tanaka K, Thomas T, Wang Y, Cremers S, Hen R, Krust A, Chambon P, Karsenty G. Leptin-dependent serotonin control of appetite: temporal specificity, transcriptional regulation, and therapeutic implications. The Journal of Experimental Medicine. 208: 41-52. PMID 21187319 DOI: 10.1084/jem.20101940  1
2011 Kheirbek MA, Hen R. Dorsal vs ventral hippocampal neurogenesis: implications for cognition and mood. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 373-4. PMID 21116266 DOI: 10.1038/npp.2010.148  1
2011 Yadav VK, Oury F, Tanaka KF, Thomas T, Wang Y, Cremers S, Hen R, Krust A, Chambon P, Karsenty G. Leptin-dependent serotonin control of appetite: Temporal specificity, transcriptional regulation, and therapeutic implications (The Journal of Experimental Medicine (2011) 208, 1, (41-52)) Journal of Experimental Medicine. 208: 413. DOI: 10.1084/jem.201019402082c  1
2011 Samuels BA, Hen R. Novelty-suppressed feeding in the mouse Neuromethods. 63: 107-121. DOI: 10.1007/978-1-61779-313-4_7  1
2010 David DJ, Wang J, Samuels BA, Rainer Q, David I, Gardier AM, Hen R. Implications of the functional integration of adult-born hippocampal neurons in anxiety-depression disorders. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 16: 578-91. PMID 20889967 DOI: 10.1177/1073858409360281  1
2010 Drew MR, Denny CA, Hen R. Arrest of adult hippocampal neurogenesis in mice impairs single- but not multiple-trial contextual fear conditioning. Behavioral Neuroscience. 124: 446-54. PMID 20695644 DOI: 10.1037/a0020081  1
2010 Segu L, Lecomte MJ, Wolff M, Santamaria J, Hen R, Dumuis A, Berrard S, Bockaert J, Buhot MC, Compan V. Hyperfunction of muscarinic receptor maintains long-term memory in 5-HT4 receptor knock-out mice. Plos One. 5: e9529. PMID 20209108 DOI: 10.1371/journal.pone.0009529  0.56
2010 Crupi R, Cambiaghi M, Spatz L, Hen R, Thorn M, Friedman E, Vita G, Battaglia F. Reduced adult neurogenesis and altered emotional behaviors in autoimmune-prone B-cell activating factor transgenic mice. Biological Psychiatry. 67: 558-66. PMID 20185032 DOI: 10.1016/j.biopsych.2009.12.008  0.36
2010 Tanaka KF, Ahmari SE, Leonardo ED, Richardson-Jones JW, Budreck EC, Scheiffele P, Sugio S, Inamura N, Ikenaka K, Hen R. Flexible Accelerated STOP Tetracycline Operator-knockin (FAST): a versatile and efficient new gene modulating system. Biological Psychiatry. 67: 770-3. PMID 20163789 DOI: 10.1016/j.biopsych.2009.12.020  1
2010 Richardson-Jones JW, Craige CP, Guiard BP, Stephen A, Metzger KL, Kung HF, Gardier AM, Dranovsky A, David DJ, Beck SG, Hen R, Leonardo ED. 5-HT1A autoreceptor levels determine vulnerability to stress and response to antidepressants. Neuron. 65: 40-52. PMID 20152112 DOI: 10.1016/j.neuron.2009.12.003  1
2010 Richardson-Jones JW, Leonardo ED, Hen R, Ahmari SE. Animal models of anxiety disorders: Behavioral and genetic approaches Anxiety Disorders: Theory, Research, and Clinical Perspectives. 156-167. DOI: 10.1017/CBO9780511777578.016  1
2010 Ahmari SE, Alter MD, Hen R. Aversive Emotions: Genetic Mechanisms of Serotonin Encyclopedia of Neuroscience. 1039-1045. DOI: 10.1016/B978-008045046-9.00834-2  1
2009 Rainer Q, Gardier AM, Hen R, David DJ. [Neurogenesis-dependent and independent effects of anti-depressant drugs]. Medecine Sciences : M/S. 25: 795-8. PMID 19849978 DOI: 10.1051/medsci/20092510795  1
2009 Yadav VK, Oury F, Suda N, Liu ZW, Gao XB, Confavreux C, Klemenhagen KC, Tanaka KF, Gingrich JA, Guo XE, Tecott LH, Mann JJ, Hen R, Horvath TL, Karsenty G. A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure. Cell. 138: 976-89. PMID 19737523 DOI: 10.1016/j.cell.2009.06.051  1
2009 Scobie KN, Hall BJ, Wilke SA, Klemenhagen KC, Fujii-Kuriyama Y, Ghosh A, Hen R, Sahay A. Krüppel-like factor 9 is necessary for late-phase neuronal maturation in the developing dentate gyrus and during adult hippocampal neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9875-87. PMID 19657039 DOI: 10.1523/JNEUROSCI.2260-09.2009  1
2009 Liu MT, Kuan YH, Wang J, Hen R, Gershon MD. 5-HT4 receptor-mediated neuroprotection and neurogenesis in the enteric nervous system of adult mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9683-99. PMID 19657021 DOI: 10.1523/JNEUROSCI.1145-09.2009  0.68
2009 Boldrini M, Underwood MD, Hen R, Rosoklija GB, Dwork AJ, John Mann J, Arango V. Antidepressants increase neural progenitor cells in the human hippocampus. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2376-89. PMID 19606083 DOI: 10.1038/npp.2009.75  0.68
2009 Alter MD, Gilani AI, Champagne FA, Curley JP, Turner JB, Hen R. Paternal transmission of complex phenotypes in inbred mice. Biological Psychiatry. 66: 1061-6. PMID 19577226 DOI: 10.1016/j.biopsych.2009.05.026  0.52
2009 Alter MD, Hen R. Is there a genomic tone? Implications for understanding development, adaptation and treatment. Developmental Neuroscience. 31: 351-7. PMID 19546572 DOI: 10.1159/000216546  0.36
2009 Gaisler-Salomon I, Miller GM, Chuhma N, Lee S, Zhang H, Ghoddoussi F, Lewandowski N, Fairhurst S, Wang Y, Conjard-Duplany A, Masson J, Balsam P, Hen R, Arancio O, Galloway MP, et al. Glutaminase-deficient mice display hippocampal hypoactivity, insensitivity to pro-psychotic drugs and potentiated latent inhibition: relevance to schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2305-22. PMID 19516252 DOI: 10.1038/npp.2009.58  0.36
2009 David DJ, Samuels BA, Rainer Q, Wang JW, Marsteller D, Mendez I, Drew M, Craig DA, Guiard BP, Guilloux JP, Artymyshyn RP, Gardier AM, Gerald C, Antonijevic IA, Leonardo ED, ... Hen R, et al. Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression. Neuron. 62: 479-93. PMID 19477151 DOI: 10.1016/j.neuron.2009.04.017  1
2009 Deltheil T, Tanaka K, Reperant C, Hen R, David DJ, Gardier AM. Synergistic neurochemical and behavioural effects of acute intrahippocampal injection of brain-derived neurotrophic factor and antidepressants in adult mice. The International Journal of Neuropsychopharmacology. 12: 905-15. PMID 19236729 DOI: 10.1017/S1461145709000017  1
2009 Moulin-Sallanon M, Charnay Y, Ginovart N, Perret P, Lanfumey L, Hamon M, Hen R, Fagret D, Ibáñez V, Millet P. Acute and chronic effects of citalopram on 5-HT1A receptor-labeling by [18F]MPPF and -coupling to receptors-G proteins. Synapse (New York, N.Y.). 63: 106-16. PMID 19016488 DOI: 10.1002/syn.20588  0.4
2009 Shanahan NA, Holick Pierz KA, Masten VL, Waeber C, Ansorge M, Gingrich JA, Geyer MA, Hen R, Dulawa SC. Chronic reductions in serotonin transporter function prevent 5-HT1B-induced behavioral effects in mice. Biological Psychiatry. 65: 401-8. PMID 19013555 DOI: 10.1016/j.biopsych.2008.09.026  1
2009 Yadav VK, Ryu JH, Suda N, Tanaka KF, Gingrich JA, Schütz G, Glorieux FH, Chiang CY, Zajac JD, Insogna KL, John Mann J, Hen R, Ducy P, Karsenty G. LDL-receptor related protein five controls bone formation by inhibiting serotonin synthesis in the duodenum Obstetrical and Gynecological Survey. 64: 240-242. DOI: 10.1097/01.ogx.0000345723.85624.24  1
2008 Alter MD, Hen R. Putting a KAP on transcription and stress. Neuron. 60: 733-5. PMID 19081366 DOI: 10.1016/j.neuron.2008.12.002  0.36
2008 Yadav VK, Ryu JH, Suda N, Tanaka KF, Gingrich JA, Schütz G, Glorieux FH, Chiang CY, Zajac JD, Insogna KL, Mann JJ, Hen R, Ducy P, Karsenty G. Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum. Cell. 135: 825-37. PMID 19041748 DOI: 10.1016/j.cell.2008.09.059  1
2008 Alter MD, Rubin DB, Ramsey K, Halpern R, Stephan DA, Abbott LF, Hen R. Variation in the large-scale organization of gene expression levels in the hippocampus relates to stable epigenetic variability in behavior. Plos One. 3: e3344. PMID 18836535 DOI: 10.1371/journal.pone.0003344  0.36
2008 Deltheil T, Guiard BP, Cerdan J, David DJ, Tanaka KF, Repérant C, Guilloux JP, Coudoré F, Hen R, Gardier AM. Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice. Neuropharmacology. 55: 1006-14. PMID 18761360 DOI: 10.1016/j.neuropharm.2008.08.001  1
2008 Sahay A, Hen R. Hippocampal neurogenesis and depression. Novartis Foundation Symposium. 289: 152-60; discussion 1. PMID 18497101  1
2008 Ase AR, Reader TA, Hen R, Descarries L. Regionally selective changes in neurotransmitter receptors in the brain of the 5-HT1B knockout mouse. Journal of Chemical Neuroanatomy. 35: 356-63. PMID 18406571 DOI: 10.1016/j.jchemneu.2008.02.007  1
2008 Surget A, Saxe M, Leman S, Ibarguen-Vargas Y, Chalon S, Griebel G, Hen R, Belzung C. Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal. Biological Psychiatry. 64: 293-301. PMID 18406399 DOI: 10.1016/j.biopsych.2008.02.022  0.92
2008 Wang JW, Dranovsky A, Hen R. The when and where of BDNF and the antidepressant response. Biological Psychiatry. 63: 640-1. PMID 18329441 DOI: 10.1016/j.biopsych.2008.01.008  0.68
2008 Wang JW, David DJ, Monckton JE, Battaglia F, Hen R. Chronic fluoxetine stimulates maturation and synaptic plasticity of adult-born hippocampal granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1374-84. PMID 18256257 DOI: 10.1523/JNEUROSCI.3632-07.2008  1
2008 Leonardo ED, Hen R. Anxiety as a developmental disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 134-40. PMID 17851538 DOI: 10.1038/sj.npp.1301569  0.88
2008 Guiard BP, David DJ, Deltheil T, Chenu F, Le Maître E, Renoir T, Leroux-Nicollet I, Sokoloff P, Lanfumey L, Hamon M, Andrews AM, Hen R, Gardier AM. Brain-derived neurotrophic factor-deficient mice exhibit a hippocampal hyperserotonergic phenotype. The International Journal of Neuropsychopharmacology. 11: 79-92. PMID 17559709 DOI: 10.1017/S1461145707007857  1
2008 Holick KA, Lee DC, Hen R, Dulawa SC. Behavioral effects of chronic fluoxetine in BALB/cJ mice do not require adult hippocampal neurogenesis or the serotonin 1A receptor. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 406-17. PMID 17429410 DOI: 10.1038/sj.npp.1301399  1
2008 Bothwell M, Akil H, Hen R, Spedding M, Sendtner M, Tongiorgi E, Chao M, Malaspina D, Raff MC, Castrén E. Discussion Novartis Foundation Symposium. 289: 233-237.  1
2008 Chao M, Flint J, Giedd JN, Malaspina D, Hen R, Spedding M, Owen MJ, Sklar P, Akil H, Buonanno A. General discussion II Novartis Foundation Symposium. 289: 193-195.  1
2007 Jean A, Conductier G, Manrique C, Bouras C, Berta P, Hen R, Charnay Y, Bockaert J, Compan V. Anorexia induced by activation of serotonin 5-HT4 receptors is mediated by increases in CART in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. 104: 16335-40. PMID 17913892 DOI: 10.1073/pnas.0701471104  0.56
2007 Dranovsky A, Hen R. DISC1 puts the brakes on neurogenesis. Cell. 130: 981-3. PMID 17889641 DOI: 10.1016/j.cell.2007.09.004  0.68
2007 Sahay A, Drew MR, Hen R. Dentate gyrus neurogenesis and depression. Progress in Brain Research. 163: 697-722. PMID 17765746 DOI: 10.1016/S0079-6123(07)63038-6  1
2007 Sahay A, Hen R. Adult hippocampal neurogenesis in depression. Nature Neuroscience. 10: 1110-5. PMID 17726477 DOI: 10.1038/nn1969  1
2007 Drew MR, Hen R. Adult hippocampal neurogenesis as target for the treatment of depression. Cns & Neurological Disorders Drug Targets. 6: 205-18. PMID 17511617  1
2007 Perera TD, Coplan JD, Lisanby SH, Lipira CM, Arif M, Carpio C, Spitzer G, Santarelli L, Scharf B, Hen R, Rosoklija G, Sackeim HA, Dwork AJ. Antidepressant-induced neurogenesis in the hippocampus of adult nonhuman primates. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4894-901. PMID 17475797 DOI: 10.1523/JNEUROSCI.0237-07.2007  0.68
2007 Sibille E, Su J, Leman S, Le Guisquet AM, Ibarguen-Vargas Y, Joeyen-Waldorf J, Glorioso C, Tseng GC, Pezzone M, Hen R, Belzung C. Lack of serotonin1B receptor expression leads to age-related motor dysfunction, early onset of brain molecular aging and reduced longevity. Molecular Psychiatry. 12: 1042-56, 975. PMID 17420766 DOI: 10.1038/sj.mp.4001990  1
2007 Saxe MD, Malleret G, Vronskaya S, Mendez I, Garcia AD, Sofroniew MV, Kandel ER, Hen R. Paradoxical influence of hippocampal neurogenesis on working memory. Proceedings of the National Academy of Sciences of the United States of America. 104: 4642-6. PMID 17360577 DOI: 10.1073/pnas.0611718104  0.52
2007 Sanders AC, Hussain AJ, Hen R, Zhuang X. Chronic blockade or constitutive deletion of the serotonin transporter reduces operant responding for food reward. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 2321-9. PMID 17356573 DOI: 10.1038/sj.npp.1301368  1
2007 David DJ, Klemenhagen KC, Holick KA, Saxe MD, Mendez I, Santarelli L, Craig DA, Zhong H, Swanson CJ, Hegde LG, Ping XI, Dong D, Marzabadi MR, Gerald CP, Hen R. Efficacy of the MCHR1 antagonist N-[3-(1-{[4-(3,4-difluorophenoxy)phenyl]methyl}(4-piperidyl))-4-methylphenyl]-2-methylpropanamide (SNAP 94847) in mouse models of anxiety and depression following acute and chronic administration is independent of hippocampal neurogenesis. The Journal of Pharmacology and Experimental Therapeutics. 321: 237-48. PMID 17237257 DOI: 10.1124/jpet.106.109678  1
2007 Scharfman HE, Hen R. Neuroscience. Is more neurogenesis always better? Science (New York, N.Y.). 315: 336-8. PMID 17234934 DOI: 10.1126/science.1138711  0.36
2007 Stark KL, Gross C, Richardson-Jones J, Zhuang X, Hen R. A novel conditional knockout strategy applied to serotonin receptors. Handbook of Experimental Pharmacology. 347-63. PMID 17203662 DOI: 10.1007/978-3-540-35109-2_14  1
2007 Ansorge MS, Hen R, Gingrich JA. Neurodevelopmental origins of depressive disorders. Current Opinion in Pharmacology. 7: 8-17. PMID 17188022 DOI: 10.1016/j.coph.2006.11.006  0.4
2007 Gobbi G, Cassano T, Radja F, Morgese MG, Cuomo V, Santarelli L, Hen R, Blier P. Neurokinin 1 receptor antagonism requires norepinephrine to increase serotonin function. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 17: 328-38. PMID 16950604 DOI: 10.1016/j.euroneuro.2006.07.004  0.48
2007 Sibille E, Su J, Leman S, Le Guisquet AM, Ibarguen-Vargas Y, Joeyen-Waldorf J, Glorioso C, Tseng GC, Pezzone M, Hen R, Belzung C. Upregulated sirtuin 5 gene expression in frontal cortex of serotonin 1b receptor knock out mice Molecular Psychiatry. 12: 975. DOI: 10.1038/sj.mp.4002115  1
2007 Ansorge MS, Hen R, Gingrich JA. Neurodevelopmental origins of depressive disorders (DOI:10.1016/j.coph.2006.11.006) Current Opinion in Pharmacology. 7: 234. DOI: 10.1016/j.coph.2007.02.002  1
2006 Saxe MD, Battaglia F, Wang JW, Malleret G, David DJ, Monckton JE, Garcia AD, Sofroniew MV, Kandel ER, Santarelli L, Hen R, Drew MR. Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus. Proceedings of the National Academy of Sciences of the United States of America. 103: 17501-6. PMID 17088541 DOI: 10.1073/pnas.0607207103  1
2006 Gordon JA, Hen R. TREKing toward new antidepressants. Nature Neuroscience. 9: 1081-3. PMID 16936765 DOI: 10.1038/nn0906-1081  0.96
2006 Conductier G, Dusticier N, Lucas G, Côté F, Debonnel G, Daszuta A, Dumuis A, Nieoullon A, Hen R, Bockaert J, Compan V. Adaptive changes in serotonin neurons of the raphe nuclei in 5-HT(4) receptor knock-out mouse. The European Journal of Neuroscience. 24: 1053-62. PMID 16930432 DOI: 10.1111/j.1460-9568.2006.04943.x  0.56
2006 Weisstaub NV, Zhou M, Lira A, Lambe E, González-Maeso J, Hornung JP, Sibille E, Underwood M, Itohara S, Dauer WT, Ansorge MS, Morelli E, Mann JJ, Toth M, Aghajanian G, ... ... Hen R, et al. Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice. Science (New York, N.Y.). 313: 536-40. PMID 16873667 DOI: 10.1126/science.1123432  1
2006 Dranovsky A, Hen R. Hippocampal neurogenesis: regulation by stress and antidepressants. Biological Psychiatry. 59: 1136-43. PMID 16797263 DOI: 10.1016/j.biopsych.2006.03.082  0.68
2006 Meshi D, Drew MR, Saxe M, Ansorge MS, David D, Santarelli L, Malapani C, Moore H, Hen R. Hippocampal neurogenesis is not required for behavioral effects of environmental enrichment. Nature Neuroscience. 9: 729-31. PMID 16648847 DOI: 10.1038/nn1696  1
2006 Masson J, Darmon M, Conjard A, Chuhma N, Ropert N, Thoby-Brisson M, Foutz AS, Parrot S, Miller GM, Jorisch R, Polan J, Hamon M, Hen R, Rayport S. Mice lacking brain/kidney phosphate-activated glutaminase have impaired glutamatergic synaptic transmission, altered breathing, disorganized goal-directed behavior and die shortly after birth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4660-71. PMID 16641247 DOI: 10.1523/JNEUROSCI.4241-05.2006  0.32
2006 Leonardo ED, Hen R. Genetics of affective and anxiety disorders. Annual Review of Psychology. 57: 117-37. PMID 16318591 DOI: 10.1146/annurev.psych.57.102904.190118  0.88
2006 Leonardo ED, Richardson-Jones JW, Sibille E, Kottman A, Hen R. Molecular heterogeneity along the dorsal-ventral axis of the murine hippocampal CA1 field: a microarray analysis of gene expression. Neuroscience. 137: 177-86. PMID 16309847 DOI: 10.1016/j.neuroscience.2005.08.082  1
2006 Klemenhagen KC, Gordon JA, David DJ, Hen R, Gross CT. Increased fear response to contextual cues in mice lacking the 5-HT1A receptor. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 101-11. PMID 15920501 DOI: 10.1038/sj.npp.1300774  1
2005 Gordon JA, Lacefield CO, Kentros CG, Hen R. State-dependent alterations in hippocampal oscillations in serotonin 1A receptor-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6509-19. PMID 16014712 DOI: 10.1523/JNEUROSCI.1211-05.2005  0.96
2005 Dulawa SC, Hen R. Recent advances in animal models of chronic antidepressant effects: the novelty-induced hypophagia test. Neuroscience and Biobehavioral Reviews. 29: 771-83. PMID 15890403 DOI: 10.1016/j.neubiorev.2005.03.017  1
2005 Zhuang X, Masson J, Gingrich JA, Rayport S, Hen R. Targeted gene expression in dopamine and serotonin neurons of the mouse brain. Journal of Neuroscience Methods. 143: 27-32. PMID 15763133 DOI: 10.1016/j.jneumeth.2004.09.020  1
2005 Conductier G, Crosson C, Hen R, Bockaert J, Compan V. 3,4-N-methlenedioxymethamphetamine-induced hypophagia is maintained in 5-HT1B receptor knockout mice, but suppressed by the 5-HT2C receptor antagonist RS102221. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 1056-63. PMID 15668722 DOI: 10.1038/sj.npp.1300662  0.56
2004 Gross C, Hen R. Genetic and environmental factors interact to influence anxiety. Neurotoxicity Research. 6: 493-501. PMID 15639782  0.8
2004 Etkin A, Klemenhagen KC, Dudman JT, Rogan MT, Hen R, Kandel ER, Hirsch J. Individual differences in trait anxiety predict the response of the basolateral amygdala to unconsciously processed fearful faces. Neuron. 44: 1043-55. PMID 15603746 DOI: 10.1016/j.neuron.2004.12.006  0.96
2004 Wolff M, Costet P, Gross C, Hen R, Segu L, Buhot MC. Age-dependent effects of serotonin-1A receptor gene deletion in spatial learning abilities in mice. Brain Research. Molecular Brain Research. 130: 39-48. PMID 15519675 DOI: 10.1016/j.molbrainres.2004.07.012  0.8
2004 Ansorge MS, Zhou M, Lira A, Hen R, Gingrich JA. Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice. Science (New York, N.Y.). 306: 879-81. PMID 15514160 DOI: 10.1126/science.1101678  0.4
2004 El-Khodor BF, Dimmler MH, Amara DA, Hofer M, Hen R, Brunner D. Juvenile 5HT(1B) receptor knockout mice exhibit reduced pharmacological sensitivity to 5HT(1A) receptor activation. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 22: 405-13. PMID 15380839 DOI: 10.1016/j.ijdevneu.2004.06.001  0.4
2004 Gordon JA, Hen R. Genetic approaches to the study of anxiety. Annual Review of Neuroscience. 27: 193-222. PMID 15217331 DOI: 10.1146/annurev.neuro.27.070203.144212  0.96
2004 Gross C, Hen R. The developmental origins of anxiety. Nature Reviews. Neuroscience. 5: 545-52. PMID 15208696 DOI: 10.1038/nrn1429  0.8
2004 Blier P, Gobbi G, Haddjeri N, Santarelli L, Mathew G, Hen R. Impact of substance P receptor antagonism on the serotonin and norepinephrine systems: relevance to the antidepressant/anxiolytic response. Journal of Psychiatry & Neuroscience : Jpn. 29: 208-18. PMID 15173897  0.48
2004 Compan V, Charnay Y, Dusticier N, Daszuta A, Hen R, Bockaert J. [Feeding disorders in 5-HT4 receptor knockout mice]. Journal De La Societe De Biologie. 198: 37-49. PMID 15146954  0.56
2004 Dulawa SC, Holick KA, Gundersen B, Hen R. Effects of chronic fluoxetine in animal models of anxiety and depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1321-30. PMID 15085085 DOI: 10.1038/sj.npp.1300433  1
2004 Gordon JA, Hen R. The serotonergic system and anxiety. Neuromolecular Medicine. 5: 27-40. PMID 15001810 DOI: 10.1385/NMM:5:1:027  0.96
2004 Chuhma N, Zhang H, Masson J, Zhuang X, Sulzer D, Hen R, Rayport S. Dopamine neurons mediate a fast excitatory signal via their glutamatergic synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 972-81. PMID 14749442 DOI: 10.1523/JNEUROSCI.4317-03.2004  1
2004 Compan V, Zhou M, Grailhe R, Gazzara RA, Martin R, Gingrich J, Dumuis A, Brunner D, Bockaert J, Hen R. Attenuated response to stress and novelty and hypersensitivity to seizures in 5-HT4 receptor knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 412-9. PMID 14724239 DOI: 10.1523/JNEUROSCI.2806-03.2004  0.56
2003 Buhot MC, Wolff M, Benhassine N, Costet P, Hen R, Segu L. Spatial learning in the 5-HT1B receptor knockout mouse: selective facilitation/impairment depending on the cognitive demand. Learning & Memory (Cold Spring Harbor, N.Y.). 10: 466-77. PMID 14657258 DOI: 10.1101/lm.60203  0.4
2003 Lira A, Zhou M, Castanon N, Ansorge MS, Gordon JA, Francis JH, Bradley-Moore M, Lira J, Underwood MD, Arango V, Kung HF, Hofer MA, Hen R, Gingrich JA. Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice. Biological Psychiatry. 54: 960-71. PMID 14625138  0.96
2003 Wolff M, Benhassine N, Costet P, Hen R, Segu L, Buhot MC. Delay-dependent working memory impairment in young-adult and aged 5-HT1BKO mice as assessed in a radial-arm water maze. Learning & Memory (Cold Spring Harbor, N.Y.). 10: 401-9. PMID 14557613 DOI: 10.1101/lm.60103  0.4
2003 González-Maeso J, Yuen T, Ebersole BJ, Wurmbach E, Lira A, Zhou M, Weisstaub N, Hen R, Gingrich JA, Sealfon SC. Transcriptome fingerprints distinguish hallucinogenic and nonhallucinogenic 5-hydroxytryptamine 2A receptor agonist effects in mouse somatosensory cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8836-43. PMID 14523084  0.4
2003 Santarelli L, Saxe M, Gross C, Surget A, Battaglia F, Dulawa S, Weisstaub N, Lee J, Duman R, Arancio O, Belzung C, Hen R. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science (New York, N.Y.). 301: 805-9. PMID 12907793 DOI: 10.1126/science.1083328  0.88
2003 Compan V, Scearce-Levie K, Crosson C, Daszuta A, Hen R. Enkephalin contributes to the locomotor stimulating effects of 3,4-methylenedioxy-N-methylamphetamine. The European Journal of Neuroscience. 18: 383-90. PMID 12887420 DOI: 10.1046/j.1460-9568.2003.02767.x  1
2003 Gardier AM, David DJ, Jego G, Przybylski C, Jacquot C, Durier S, Gruwez B, Douvier E, Beauverie P, Poisson N, Hen R, Bourin M. Effects of chronic paroxetine treatment on dialysate serotonin in 5-HT1B receptor knockout mice. Journal of Neurochemistry. 86: 13-24. PMID 12807420  1
2003 Buhot MC, Wolff M, Savova M, Malleret G, Hen R, Segu L. Protective effect of 5-HT1B receptor gene deletion on the age-related decline in spatial learning abilities in mice. Behavioural Brain Research. 142: 135-42. PMID 12798274  0.4
2003 Ralph-Williams RJ, Paulus MP, Zhuang X, Hen R, Geyer MA. Valproate attenuates hyperactive and perseverative behaviors in mutant mice with a dysregulated dopamine system. Biological Psychiatry. 53: 352-9. PMID 12586455  1
2003 Wolff M, Savova M, Malleret G, Hen R, Segu L, Buhot MC. Serotonin 1B knockout mice exhibit a task-dependent selective learning facilitation. Neuroscience Letters. 338: 1-4. PMID 12565126 DOI: 10.1016/S0304-3940(02)01339-3  1
2003 Weller A, Leguisamo AC, Towns L, Ramboz S, Bagiella E, Hofer M, Hen R, Brunner D. Maternal effects in infant and adult phenotypes of 5HT1A and 5HT1B receptor knockout mice. Developmental Psychobiology. 42: 194-205. PMID 12555283 DOI: 10.1002/dev.10079  0.4
2002 Santarelli L, Gobbi G, Blier P, Hen R. Behavioral and physiologic effects of genetic or pharmacologic inactivation of the substance P receptor (NK1). The Journal of Clinical Psychiatry. 63: 11-7. PMID 12562138  0.48
2002 Dauer W, Kholodilov N, Vila M, Trillat AC, Goodchild R, Larsen KE, Staal R, Tieu K, Schmitz Y, Yuan CA, Rocha M, Jackson-Lewis V, Hersch S, Sulzer D, Przedborski S, ... ... Hen R, et al. Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP. Proceedings of the National Academy of Sciences of the United States of America. 99: 14524-9. PMID 12376616 DOI: 10.1073/pnas.172514599  0.64
2002 Nestler EJ, Gould E, Manji H, Buncan M, Duman RS, Greshenfeld HK, Hen R, Koester S, Lederhendler I, Meaney M, Robbins T, Winsky L, Zalcman S. Preclinical models: status of basic research in depression. Biological Psychiatry. 52: 503-28. PMID 12361666 DOI: 10.1016/S0006-3223(02)01405-1  0.48
2002 Ase AR, Sénécal J, Reader TA, Hen R, Descarries L. Decreased G-protein coupling of serotonin 5-HT(1A) receptors in the brain of 5-HT(1B) knockout mouse. Neuropharmacology. 42: 941-9. PMID 12069904 DOI: 10.1016/S0028-3908(02)00045-X  1
2002 Bonaventure P, Nepomuceno D, Kwok A, Chai W, Langlois X, Hen R, Stark K, Carruthers N, Lovenberg TW. Reconsideration of 5-hydroxytryptamine (5-HT)(7) receptor distribution using [(3)H]5-carboxamidotryptamine and [(3)H]8-hydroxy-2-(di-n-propylamino)tetraline: analysis in brain of 5-HT(1A) knockout and 5-HT(1A/1B) double-knockout mice. The Journal of Pharmacology and Experimental Therapeutics. 302: 240-8. PMID 12065723  0.36
2002 Malagié I, David DJ, Jolliet P, Hen R, Bourin M, Gardier AM. Improved efficacy of fluoxetine in increasing hippocampal 5-hydroxytryptamine outflow in 5-HT(1B) receptor knock-out mice. European Journal of Pharmacology. 443: 99-104. PMID 12044798  1
2002 Upton AL, Ravary A, Salichon N, Moessner R, Lesch KP, Hen R, Seif I, Gaspar P. Lack of 5-HT(1B) receptor and of serotonin transporter have different effects on the segregation of retinal axons in the lateral geniculate nucleus compared to the superior colliculus. Neuroscience. 111: 597-610. PMID 12031347 DOI: 10.1016/S0306-4522(01)00602-9  1
2002 Fiorica-Howells E, Hen R, Gingrich J, Li Z, Gershon MD. 5-HT(2A) receptors: location and functional analysis in intestines of wild-type and 5-HT(2A) knockout mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 282: G877-93. PMID 11960784 DOI: 10.1152/ajpgi.00435.2001  0.4
2002 Gross C, Zhuang X, Stark K, Ramboz S, Oosting R, Kirby L, Santarelli L, Beck S, Hen R. Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult. Nature. 416: 396-400. PMID 11919622 DOI: 10.1038/416396a  1
2002 Richer M, Hen R, Blier P. Modification of serotonin neuron properties in mice lacking 5-HT1A receptors. European Journal of Pharmacology. 435: 195-203. PMID 11821026  0.32
2001 Bronsert MR, Mead AN, Hen R, Rocha BA. Amphetamine-induced locomotor activation in 5-HT(1B) knockout mice: effects of injection route on acute and sensitized responses. Behavioural Pharmacology. 12: 549-55. PMID 11795245  1
2001 Sibille E, Hen R. Serotonin(1A) receptors in mood disorders: a combined genetic and genomic approach. Behavioural Pharmacology. 12: 429-38. PMID 11742136  1
2001 Yamamoto A, Hen R, Dauer WT. The ons and offs of inducible transgenic technology: a review. Neurobiology of Disease. 8: 923-32. PMID 11741388 DOI: 10.1006/nbdi.2001.0452  1
2001 Sibille E, Hen R. Combining genetic and genomic approaches to study mood disorders. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 11: 413-21. PMID 11704418 DOI: 10.1016/S0924-977X(01)00118-3  1
2001 Martín-Aparicio E, Yamamoto A, Hernández F, Hen R, Avila J, Lucas JJ. Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 8772-81. PMID 11698589  1
2001 Gardier AM, Gruwez B, Trillat AC, Jacquot C, Hen R, Bourin M. Interaction between 5-HT(1A) and 5-HT(1B) receptors: effects of 8-OH-DPAT-induced hypothermia in 5-HT(1B) receptor knockout mice. European Journal of Pharmacology. 421: 171-5. PMID 11516433 DOI: 10.1016/S0014-2999(01)01037-8  1
2001 Mayorga AJ, Dalvi A, Page ME, Zimov-Levinson S, Hen R, Lucki I. Antidepressant-like behavioral effects in 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) receptor mutant mice. The Journal of Pharmacology and Experimental Therapeutics. 298: 1101-7. PMID 11504807  1
2001 Knobelman DA, Hen R, Blendy JA, Lucki I. Regional patterns of compensation following genetic deletion of either 5-hydroxytryptamine(1A) or 5-hydroxytryptamine(1B) receptor in the mouse. The Journal of Pharmacology and Experimental Therapeutics. 298: 1092-100. PMID 11504806  1
2001 Knobelman DA, Hen R, Lucki I. Genetic regulation of extracellular serotonin by 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) autoreceptors in different brain regions of the mouse. The Journal of Pharmacology and Experimental Therapeutics. 298: 1083-91. PMID 11504805  1
2001 Ase AR, Reader TA, Hen R, Riad M, Descarries L. Regional changes in density of serotonin transporter in the brain of 5-HT1A and 5-HT1B knockout mice, and of serotonin innervation in the 5-HT1B knockout. Journal of Neurochemistry. 78: 619-30. PMID 11483665 DOI: 10.1046/j.1471-4159.2001.00437.x  1
2001 Gardier AM, Trillat AC, Malagié I, David D, Hascoët M, Colombel MC, Jolliet P, Jacquot C, Hen R, Bourin M. [5-HT1B serotonin receptors and antidepressant effects of selective serotonin reuptake inhibitors ]. Comptes Rendus De L'AcadéMie Des Sciences. SéRie Iii, Sciences De La Vie. 324: 433-41. PMID 11417564 DOI: 10.1016/S0764-4469(01)01332-4  1
2001 Gingrich JA, Hen R. Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice. Psychopharmacology. 155: 1-10. PMID 11374326 DOI: 10.1007/s002130000573  1
2001 Grailhe R, Grabtree GW, Hen R. Human 5-HT(5) receptors: the 5-HT(5A) receptor is functional but the 5-HT(5B) receptor was lost during mammalian evolution. European Journal of Pharmacology. 418: 157-67. PMID 11343685 DOI: 10.1016/S0014-2999(01)00933-5  1
2001 Pattij T, Hijzen TH, Groenink L, Oosting RS, van der Gugten J, Maes RA, Hen R, Olivier B. Stress-induced hyperthermia in the 5-HT(1A) receptor knockout mouse is normal. Biological Psychiatry. 49: 569-74. PMID 11297713 DOI: 10.1016/S0006-3223(00)01022-2  1
2001 Lucas JJ, Hernández F, Gómez-Ramos P, Morán MA, Hen R, Avila J. Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice. The Embo Journal. 20: 27-39. PMID 11226152 DOI: 10.1093/emboj/20.1.27  1
2001 Zhuang X, Oosting RS, Jones SR, Gainetdinov RR, Miller GW, Caron MG, Hen R. Hyperactivity and impaired response habituation in hyperdopaminergic mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 1982-7. PMID 11172062 DOI: 10.1073/pnas.98.4.1982  1
2001 Santarelli L, Gobbi G, Debs PC, Sibille ET, Blier P, Hen R, Heath MJ. Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function. Proceedings of the National Academy of Sciences of the United States of America. 98: 1912-7. PMID 11172050 DOI: 10.1073/pnas.041596398  1
2001 Dirks A, Pattij T, Bouwknecht JA, Westphal TT, Hijzen TH, Groenink L, van der Gugten J, Oosting RS, Hen R, Geyer MA, Olivier B. 5-HT1B receptor knockout, but not 5-HT1A receptor knockout mice, show reduced startle reactivity and footshock-induced sensitization, as measured with the acoustic startle response. Behavioural Brain Research. 118: 169-78. PMID 11164514 DOI: 10.1016/S0166-4328(00)00326-0  1
2001 Malagié I, Trillat AC, Bourin M, Jacquot C, Hen R, Gardier AM. 5-HT1B Autoreceptors limit the effects of selective serotonin re-uptake inhibitors in mouse hippocampus and frontal cortex. Journal of Neurochemistry. 76: 865-71. PMID 11158258 DOI: 10.1046/j.1471-4159.2001.00083.x  0.52
2001 Salichon N, Gaspar P, Upton AL, Picaud S, Hanoun N, Hamon M, De Maeyer E, Murphy DL, Mossner R, Lesch KP, Hen R, Seif I. Excessive activation of serotonin (5-HT) 1B receptors disrupts the formation of sensory maps in monoamine oxidase a and 5-ht transporter knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 884-96. PMID 11157075  1
2000 Bouwknecht JA, Hijzen TH, van der Gugten J, Dirks A, Maes RA, Hen R, Geyer MA, Olivier B. Startle responses, heart rate, and temperature in 5-HT1B receptor knockout mice. Neuroreport. 11: 4097-102. PMID 11192635  0.68
2000 Castanon N, Scearce-Levie K, Lucas JJ, Rocha B, Hen R. Modulation of the effects of cocaine by 5-HT1B receptors: a comparison of knockouts and antagonists. Pharmacology, Biochemistry, and Behavior. 67: 559-66. PMID 11164086 DOI: 10.1016/S0091-3057(00)00389-0  1
2000 Gross C, Santarelli L, Brunner D, Zhuang X, Hen R. Altered fear circuits in 5-HT(1A) receptor KO mice. Biological Psychiatry. 48: 1157-63. PMID 11137057 DOI: 10.1016/S0006-3223(00)01041-6  1
2000 Ase AR, Reader TA, Hen R, Riad M, Descarries L. Altered serotonin and dopamine metabolism in the CNS of serotonin 5-HT(1A) or 5-HT(1B) receptor knockout mice. Journal of Neurochemistry. 75: 2415-26. PMID 11080193 DOI: 10.1046/j.1471-4159.2000.0752415.x  1
2000 López-Rubalcava C, Hen R, Cruz SL. Anxiolytic-like actions of toluene in the burying behavior and plus-maze tests: differences in sensitivity between 5-HT(1B) knockout and wild-type mice. Behavioural Brain Research. 115: 85-94. PMID 10996411 DOI: 10.1016/S0166-4328(00)00241-2  1
2000 Zhuang X, Belluscio L, Hen R. G(olf)alpha mediates dopamine D1 receptor signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: RC91. PMID 10924528  1
2000 Shippenberg TS, Hen R, He M. Region-specific enhancement of basal extracellular and cocaine-evoked dopamine levels following constitutive deletion of the Serotonin(1B) receptor. Journal of Neurochemistry. 75: 258-65. PMID 10854269  1
2000 Belzung C, Scearce-Levie K, Barreau S, Hen R. Absence of cocaine-induced place conditioning in serotonin 1B receptor knock-out mice. Pharmacology, Biochemistry, and Behavior. 66: 221-5. PMID 10837864 DOI: 10.1016/S0091-3057(00)00238-0  1
2000 Dulawa SC, Scearce-Levie KA, Hen R, Geyer MA. Serotonin releasers increase prepulse inhibition in serotonin 1B knockout mice. Psychopharmacology. 149: 306-12. PMID 10823412 DOI: 10.1007/s002130000373  1
2000 Dulawa SC, Gross C, Stark KL, Hen R, Geyer MA. Knockout mice reveal opposite roles for serotonin 1A and 1B receptors in prepulse inhibition. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 22: 650-9. PMID 10788764 DOI: 10.1016/S0893-133X(99)00164-5  1
2000 Yamamoto A, Lucas JJ, Hen R. Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease. Cell. 101: 57-66. PMID 10778856 DOI: 10.1016/S0092-8674(00)80623-6  1
2000 King TE, Heath MJ, Debs P, Davis MB, Hen R, Barr GA. The development of the nociceptive responses in neurokinin-1 receptor knockout mice. Neuroreport. 11: 587-91. PMID 10718319  1
2000 Gingrich JA, Hen R. The broken mouse: the role of development, plasticity and environment in the interpretation of phenotypic changes in knockout mice. Current Opinion in Neurobiology. 10: 146-52. PMID 10679442 DOI: 10.1016/S0959-4388(99)00061-6  1
2000 Battaglla E, Yamamoto A, Girlanda P, Vita G, Toscano A, Hen R, Arancio O. Impaired long-term potentiation in a conditional model of huntington's disease Neurological Sciences. 21: S134-S135.  1
1999 Stark KL, Hen R. Knockout Corner. The International Journal of Neuropsychopharmacology. 2: 145-150. PMID 11281982 DOI: 10.1017/S146114579900142X  0.92
1999 Phillips TJ, Hen R, Crabbe JC. Complications associated with genetic background effects in research using knockout mice. Psychopharmacology. 147: 5-7. PMID 10591855 DOI: 10.1007/s002130051128  1
1999 Evrard A, Laporte AM, Chastanet M, Hen R, Hamon M, Adrien J. 5-HT1A and 5-HT1B receptors control the firing of serotoninergic neurons in the dorsal raphe nucleus of the mouse: studies in 5-HT1B knock-out mice. The European Journal of Neuroscience. 11: 3823-31. PMID 10583471 DOI: 10.1046/j.1460-9568.1999.00800.x  1
1999 Hen R. Testing the genetics of behavior in mice. Science (New York, N.Y.). 285: 2068-9; author reply. PMID 10523202  1
1999 Brunner D, Buhot MC, Hen R, Hofer M. Anxiety, motor activation, and maternal-infant interactions in 5HT1B knockout mice. Behavioral Neuroscience. 113: 587-601. PMID 10443785 DOI: 10.1037/0735-7044.113.3.587  1
1999 Zhuang X, Gross C, Santarelli L, Compan V, Trillat AC, Hen R. Altered emotional states in knockout mice lacking 5-HT1A or 5-HT1B receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 21: 52S-60S. PMID 10432489 DOI: 10.1016/S0893-133X(99)00047-0  1
1999 Huang YY, Grailhe R, Arango V, Hen R, Mann JJ. Relationship of psychopathology to the human serotonin1B genotype and receptor binding kinetics in postmortem brain tissue. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 21: 238-46. PMID 10432472 DOI: 10.1016/S0893-133X(99)00030-5  1
1999 Scearce-Levie K, Chen JP, Gardner E, Hen R. 5-HT receptor knockout mice: pharmacological tools or models of psychiatric disorders. Annals of the New York Academy of Sciences. 868: 701-15. PMID 10414358 DOI: 10.1111/j.1749-6632.1999.tb11350.x  1
1999 Malleret G, Hen R, Guillou JL, Segu L, Buhot MC. 5-HT1B receptor knock-out mice exhibit increased exploratory activity and enhanced spatial memory performance in the Morris water maze. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6157-68. PMID 10407051  1
1999 Grailhe R, Waeber C, Dulawa SC, Hornung JP, Zhuang X, Brunner D, Geyer MA, Hen R. Increased exploratory activity and altered response to LSD in mice lacking the 5-HT(5A) receptor. Neuron. 22: 581-91. PMID 10197537  1
1999 Boutrel B, Franc B, Hen R, Hamon M, Adrien J. Key role of 5-HT1B receptors in the regulation of paradoxical sleep as evidenced in 5-HT1B knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 3204-12. PMID 10191333  1
1999 Ghavami A, Stark KL, Jareb M, Ramboz S, Ségu L, Hen R. Differential addressing of 5-HT1A and 5-HT1B receptors in epithelial cells and neurons. Journal of Cell Science. 112: 967-76. PMID 10036246  1
1999 Scearce-Levie K, Viswanathan SS, Hen R. Locomotor response to MDMA is attenuated in knockout mice lacking the 5-HT1B receptor. Psychopharmacology. 141: 154-61. PMID 9952039 DOI: 10.1007/s002130050819  1
1999 Stark KL, Hen R. Knockout Corner 5-HT1B receptor knockout mice: A review International Journal of Neuropsychopharmacology. 2: 145-150.  1
1998 Trillat AC, Malagié I, Bourin M, Jacquot C, Hen R, Gardier AM. [Homozygote mice deficient in serotonin 5-HT1B receptor and antidepressant effect of selective serotonin reuptake inhibitors]. Comptes Rendus Des SéAnces De La SociéTé De Biologie Et De Ses Filiales. 192: 1139-47. PMID 10101609  0.52
1998 Waeber C, Grailhe R, Yu XJ, Hen R, Moskowitz MA. Putative 5-ht5 receptors: localization in the mouse CNS and lack of effect in the inhibition of dural protein extravasation. Annals of the New York Academy of Sciences. 861: 85-90. PMID 9928243 DOI: 10.1111/j.1749-6632.1998.tb10177.x  1
1998 Dulawa SC, Hen R, Scearce-Levie K, Geyer MA. 5-HT1B receptor modulation of prepulse inhibition: recent findings in wild-type and 5-HT1B knockout mice. Annals of the New York Academy of Sciences. 861: 79-84. PMID 9928242 DOI: 10.1111/j.1749-6632.1998.tb10176.x  1
1998 Stark KL, Oosting RS, Hen R. Inducible knockout strategies to probe the functions of 5-HT receptors. Annals of the New York Academy of Sciences. 861: 57-66. PMID 9928239 DOI: 10.1111/j.1749-6632.1998.tb10173.x  1
1998 Ramboz S, Oosting R, Amara DA, Kung HF, Blier P, Mendelsohn M, Mann JJ, Brunner D, Hen R. Serotonin receptor 1A knockout: an animal model of anxiety-related disorder. Proceedings of the National Academy of Sciences of the United States of America. 95: 14476-81. PMID 9826725 DOI: 10.1073/pnas.95.24.14476  1
1998 Stark KL, Oosting RS, Hen R. Novel strategies to probe the functions of serotonin receptors. Biological Psychiatry. 44: 163-8. PMID 9693388 DOI: 10.1016/S0006-3223(98)00040-7  1
1998 Lucas JJ, Yamamoto A, Scearce-Levie K, Saudou F, Hen R. Absence of fenfluramine-induced anorexia and reduced c-Fos induction in the hypothalamus and central amygdaloid complex of serotonin 1B receptor knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 5537-44. PMID 9651234  1
1998 Rocha BA, Scearce-Levie K, Lucas JJ, Hiroi N, Castanon N, Crabbe JC, Nestler EJ, Hen R. Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor. Nature. 393: 175-8. PMID 9603521 DOI: 10.1038/30259  1
1998 Oosting RS, Stark KL, Hen R, van Scharrenburg GJM. New animal models in target discovery Pharmacochemistry Library. 29: 203-213. DOI: 10.1016/S0165-7208(98)80058-5  1
1997 Brunner D, Hen R. Insights into the neurobiology of impulsive behavior from serotonin receptor knockout mice. Annals of the New York Academy of Sciences. 836: 81-105. PMID 9616795 DOI: 10.1111/j.1749-6632.1997.tb52356.x  1
1997 Ghavami A, Baruscotti M, Robinson RB, Hen R. Adenovirus-mediated expression of 5-HT1B receptors in cardiac ventricle myocytes; coupling to inwardly rectifying K+ channels. European Journal of Pharmacology. 340: 259-66. PMID 9537822 DOI: 10.1016/S0014-2999(97)01404-0  1
1997 Trillat AC, Malagié I, Scearce K, Pons D, Anmella MC, Jacquot C, Hen R, Gardier AM. Regulation of serotonin release in the frontal cortex and ventral hippocampus of homozygous mice lacking 5-HT1B receptors: in vivo microdialysis studies. Journal of Neurochemistry. 69: 2019-25. PMID 9349547  1
1997 Coronas V, Féron F, Hen R, Sicard G, Jourdan F, Moyse E. In vitro induction of apoptosis or differentiation by dopamine in an immortalized olfactory neuronal cell line. Journal of Neurochemistry. 69: 1870-81. PMID 9349530  1
1997 Dulawa SC, Hen R, Scearce-Levie K, Geyer MA. Serotonin1B receptor modulation of startle reactivity, habituation, and prepulse inhibition in wild-type and serotonin1B knockout mice. Psychopharmacology. 132: 125-34. PMID 9266609 DOI: 10.1007/s002130050328  1
1997 Obosi LA, Hen R, Beadle DJ, Bermudez I, King LA. Mutational analysis of the mouse 5-HT7 receptor: importance of the third intracellular loop for receptor-G-protein interaction. Febs Letters. 412: 321-4. PMID 9256244 DOI: 10.1016/S0014-5793(97)00813-2  1
1997 Rocha BA, Ator R, Emmett-Oglesby MW, Hen R. Intravenous cocaine self-administration in mice lacking 5-HT1B receptors. Pharmacology, Biochemistry, and Behavior. 57: 407-12. PMID 9218264 DOI: 10.1016/S0091-3057(96)00444-3  1
1997 Lucas JJ, Segu L, Hen R. 5-Hydroxytryptamine1B receptors modulate the effect of cocaine on c-fos expression: converging evidence using 5-hydroxytryptamine1B knockout mice and the 5-hydroxytryptamine1B/1D antagonist GR127935. Molecular Pharmacology. 51: 755-63. PMID 9145913  1
1997 Grailhe R, Boschert U, Hen R. The 5-HT5, 5-HT6 and 5-HT7 receptors Pharmacochemistry Library. 27: 311-323. DOI: 10.1016/S0165-7208(97)80018-9  1
1996 Ramboz S, Saudou F, Amara DA, Belzung C, Segu L, Misslin R, Buhot MC, Hen R. 5-HT1B receptor knock out--behavioral consequences. Behavioural Brain Research. 73: 305-12. PMID 8788525 DOI: 10.1016/0166-4328(96)00119-2  1
1996 Ramboz S, Saudou F, Amara DA, Belzung C, Dierich A, LeMeur M, Segu L, Misslin R, Buhot MC, Hen R. Behavioral characterization of mice packing the 5-HT1B receptor. Nida Research Monograph. 161: 39-57. PMID 8784843  1
1996 Crabbe JC, Phillips TJ, Feller DJ, Hen R, Wenger CD, Lessov CN, Schafer GL. Elevated alcohol consumption in null mutant mice lacking 5-HT1B serotonin receptors. Nature Genetics. 14: 98-101. PMID 8782828 DOI: 10.1038/ng0996-98  1
1996 Yu XJ, Waeber C, Castanon N, Scearce K, Hen R, Macor JE, Chauveau J, Moskowitz MA, Chaveau J. 5-Carboxamido-tryptamine, CP-122,288 and dihydroergotamine but not sumatriptan, CP-93,129, and serotonin-5-O-carboxymethyl-glycyl -tyrosinamide block dural plasma protein extravasation in knockout mice that lack 5-hydroxytryptamine1B receptors. Molecular Pharmacology. 49: 761-5. PMID 8622623  0.64
1996 Hen R. Mean genes. Neuron. 16: 17-21. PMID 8562081 DOI: 10.1016/S0896-6273(00)80019-7  1
1995 Grimaldi B, Cloez-Tayarani I, Fillion MP, Mazie JC, Hen R, Fillion G. Production and characterization of an antibody directed against the mouse 5HT1B receptor. Neuroscience Research. 24: 97-101. PMID 8848295 DOI: 10.1016/0168-0102(95)00974-4  1
1995 Piñeyro G, Castanon N, Hen R, Blier P. Regulation of [3H]5-HT release in raphe, frontal cortex and hippocampus of 5-HT1B knock-out mice. Neuroreport. 7: 353-9. PMID 8742487  1
1995 Olivier B, Mos J, van Oorschot R, Hen R. Serotonin receptors and animal models of aggressive behavior. Pharmacopsychiatry. 28: 80-90. PMID 8614705 DOI: 10.1055/s-2007-979624  1
1995 Heath MJ, Hen R. Serotonin receptors. Genetic insights into serotonin function. Current Biology : Cb. 5: 997-9. PMID 8542294 DOI: 10.1016/S0960-9822(95)00199-0  1
1995 Lucas JJ, Hen R. New players in the 5-HT receptor field: genes and knockouts. Trends in Pharmacological Sciences. 16: 246-52. PMID 7667899 DOI: 10.1016/S0165-6147(00)89034-3  1
1995 Li XC, Giot JF, Kuhl D, Hen R, Kandel ER. Cloning and characterization of two related serotonergic receptors from the brain and the reproductive system of Aplysia that activate phospholipase C. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 7585-91. PMID 7472509  1
1995 Grailhe R, Hen R. 5-HT receptor knockouts: Constitutive, inducible or tissue-specific Seminars in Neuroscience. 7: 395-400. DOI: 10.1016/1044-5765(95)90003-9  1
1994 Boschert U, Amara DA, Segu L, Hen R. The mouse 5-hydroxytryptamine1B receptor is localized predominantly on axon terminals. Neuroscience. 58: 167-82. PMID 8159291 DOI: 10.1016/0306-4522(94)90164-3  1
1994 Saudou F, Amara DA, Dierich A, LeMeur M, Ramboz S, Segu L, Buhot MC, Hen R. Enhanced aggressive behavior in mice lacking 5-HT1B receptor. Science (New York, N.Y.). 265: 1875-8. PMID 8091214  1
1994 Saudou F, Hen R. 5-Hydroxytryptamine receptor subtypes in vertebrates and invertebrates. Neurochemistry International. 25: 503-32. PMID 7894328 DOI: 10.1016/0197-0186(94)90150-3  1
1994 Saudou F, Hen R. 5-Hydroxytryptamine receptor subtypes: molecular and functional diversity. Advances in Pharmacology (San Diego, Calif.). 30: 327-80. PMID 7833295 DOI: 10.1016/S1054-3589(08)60178-7  0.96
1993 Matthes H, Boschert U, Amlaiky N, Grailhe R, Plassat JL, Muscatelli F, Mattei MG, Hen R. Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization. Molecular Pharmacology. 43: 313-9. PMID 8450829  0.52
1993 Hen R. Structural and functional conservation of serotonin receptors throughout evolution. Exs. 63: 266-78. PMID 8422538  1
1993 Plassat JL, Amlaiky N, Hen R. Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase. Molecular Pharmacology. 44: 229-36. PMID 8394987  1
1993 Duclos F, Boschert U, Sirugo G, Mandel JL, Hen R, Koenig M. Gene in the region of the Friedreich ataxia locus encodes a putative transmembrane protein expressed in the nervous system. Proceedings of the National Academy of Sciences of the United States of America. 90: 109-13. PMID 7678331  1
1992 Hen R. Of mice and flies: commonalities among 5-HT receptors. Trends in Pharmacological Sciences. 13: 160-5. PMID 1589910 DOI: 10.1016/0165-6147(92)90054-A  1
1992 Maroteaux L, Saudou F, Amlaiky N, Boschert U, Plassat JL, Hen R. Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers. Proceedings of the National Academy of Sciences of the United States of America. 89: 3020-4. PMID 1557407  1
1992 Plassat JL, Boschert U, Amlaiky N, Hen R. The mouse 5HT5 receptor reveals a remarkable heterogeneity within the 5HT1D receptor family. The Embo Journal. 11: 4779-86. PMID 1464308  1
1992 Monnier D, Colas JF, Rosay P, Hen R, Borrelli E, Maroteaux L. NKD, a developmentally regulated tachykinin receptor in Drosophila. The Journal of Biological Chemistry. 267: 1298-302. PMID 1370464  1
1992 Amlaiky N, Ramboz S, Boschert U, Plassat JL, Hen R. Isolation of a mouse "5HT1E-like" serotonin receptor expressed predominantly in hippocampus. The Journal of Biological Chemistry. 267: 19761-4. PMID 1328180  1
1992 Saudou F, Boschert U, Amlaiky N, Plassat JL, Hen R. A family of Drosophila serotonin receptors with distinct intracellular signalling properties and expression patterns. The Embo Journal. 11: 7-17. PMID 1310937  1
1991 Montmayeur JP, Bausero P, Amlaiky N, Maroteaux L, Hen R, Borrelli E. Differential expression of the mouse D2 dopamine receptor isoforms. Febs Letters. 278: 239-43. PMID 1991517 DOI: 10.1016/0014-5793(91)80125-M  1
1990 Witz P, Amlaiky N, Plassat JL, Maroteaux L, Borrelli E, Hen R. Cloning and characterization of a Drosophila serotonin receptor that activates adenylate cyclase. Proceedings of the National Academy of Sciences of the United States of America. 87: 8940-4. PMID 2174167  1
1990 Saudou F, Amlaiky N, Plassat JL, Borrelli E, Hen R. Cloning and characterization of a Drosophila tyramine receptor. The Embo Journal. 9: 3611-7. PMID 2170118  1
1989 Hen R, Axel R, Obici S. Activation of the beta 2-adrenergic receptor promotes growth and differentiation in thyroid cells. Proceedings of the National Academy of Sciences of the United States of America. 86: 4785-8. PMID 2471981  1
1987 Jeltsch JM, Hen R, Maroteaux L, Garnier JM, Chambon P. Sequence of the chicken ovotransferrin gene. Nucleic Acids Research. 15: 7643-5. PMID 3658709 DOI: 10.1093/nar/15.18.7643  1
1986 Hen R, Borrelli E, Fromental C, Sassone-Corsi P, Chambon P. A mutated polyoma virus enhancer which is active in undifferentiated embryonal carcinoma cells is not repressed by adenovirus-2 E1A products. Nature. 321: 249-51. PMID 3012353 DOI: 10.1038/321249a0  1
1986 Borrelli E, Hen R, Wasylyk C, Wasylyk B, Chambon P. The immunoglobulin heavy chain enhancer is stimulated by the adenovirus type 2 E1A products in mouse fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 83: 2846-9. PMID 2939459  1
1985 Hen R, Borrelli E, Chambon P. Repression of the immunoglobulin heavy chain enhancer by the adenovirus-2 E1A products. Science (New York, N.Y.). 230: 1391-4. PMID 2999984  0.32
1984 Miyamoto NG, Moncollin V, Wintzerith M, Hen R, Egly JM, Chambon P. Stimulation of in vitro transcription by the upstream element of the adenovirus-2 major late promoter involves a specific factor. Nucleic Acids Research. 12: 8779-99. PMID 6096806 DOI: 10.1093/nar/12.23.8779  1
1984 Borrelli E, Hen R, Chambon P. Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription. Nature. 312: 608-12. PMID 6095113 DOI: 10.1038/312608a0  1
1983 Hen R, Borrelli E, Sassone-Corsi P, Chambon P. An enhancer element is located 340 base pairs upstream from the adenovirus-2 E1A capsite. Nucleic Acids Research. 11: 8747-60. PMID 6324099 DOI: 10.1093/nar/11.24.8747  1
1983 Sassone-Corsi P, Hen R, Borrelli E, Leff T, Chambon P. Far upstream sequences are required for efficient transcription from the adenovirus-2 E1A transcription unit. Nucleic Acids Research. 11: 8735-45. PMID 6324098 DOI: 10.1093/nar/11.24.8735  1
1982 Hen R, Sassone-Corsi P, Corden J, Gaub MP, Chambon P. Sequences upstream from the T-A-T-A box are required in vivo and in vitro for efficient transcription from the adenovirus serotype 2 major late promoter. Proceedings of the National Academy of Sciences of the United States of America. 79: 7132-6. PMID 6961401 DOI: 10.1073/pnas.79.23.7132  1
1981 Moreau P, Hen R, Wasylyk B, Everett R, Gaub MP, Chambon P. The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants. Nucleic Acids Research. 9: 6047-68. PMID 6273820 DOI: 10.1093/nar/9.22.6047  1
1979 Cochet M, Gannon F, Hen R, Maroteaux L, Perrin F, Chambon P. Organization and sequence studies of the 17-piece chicken conalbumin gene. Nature. 282: 567-74. PMID 551292 DOI: 10.1038/282567a0  1
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