Denis Vivien - Publications

Affiliations: 
INSERM U919, Cyceron, Caen, Caen, Normandie, France 
Area:
stroke, plasminogen activator, tgf-beta

160 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Thiebaut AM, Gauberti M, Ali C, Martinez De Lizarrondo S, Vivien D, Yepes M, Roussel BD. The role of plasminogen activators in stroke treatment: fibrinolysis and beyond. The Lancet. Neurology. 17: 1121-1132. PMID 30507392 DOI: 10.1016/S1474-4422(18)30323-5  0.44
2018 Goulay R, Drieu A, Di Palma C, Pro-Sistiaga P, Delcroix N, Chazalviel L, Saulnier R, Gakuba C, Goursaud S, Young AR, Gauberti M, Orset C, Emery E, Vivien D, Gaberel T. Modification of apparent intracerebral hematoma volume on T2-weighted images during normobaric oxygen therapy may contribute to false diagnosis. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. PMID 29571939 DOI: 10.1016/j.jocn.2018.01.046  0.48
2018 Roth S, Singh V, Tiedt S, Schindler L, Huber G, Geerlof A, Antoine DJ, Anfray A, Orset C, Gauberti M, Fournier A, Holdt LM, Harris HE, Engelhardt B, Bianchi ME, ... Vivien D, et al. Brain-released alarmins and stress response synergize in accelerating atherosclerosis progression after stroke. Science Translational Medicine. 10. PMID 29540615 DOI: 10.1126/scitranslmed.aao1313  0.48
2018 Gauberti M, Fournier AP, Docagne F, Vivien D, Martinez de Lizarrondo S. Molecular Magnetic Resonance Imaging of Endothelial Activation in the Central Nervous System. Theranostics. 8: 1195-1212. PMID 29507614 DOI: 10.7150/thno.22662  0.52
2018 Fournier AP, Gauberti M, Quenault A, Vivien D, Macrez R, Docagne F. Reduced spinal cord parenchymal cerebrospinal fluid circulation in experimental autoimmune encephalomyelitis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X18754732. PMID 29376456 DOI: 10.1177/0271678X18754732  0.52
2017 Pruvost M, Lépine M, Leonetti C, Etard O, Naveau M, Agin V, Docagne F, Maubert E, Ali C, Emery E, Vivien D. ADAMTS-4 in oligodendrocytes contributes to myelination with an impact on motor function. Glia. PMID 28850711 DOI: 10.1002/glia.23207  0.52
2017 Vaur P, Brugg B, Mericskay M, Li Z, Schmidt MS, Vivien D, Orset C, Jacotot E, Brenner C, Duplus E. Nicotinamide riboside, a form of vitamin B3, protects against excitotoxicity-induced axonal degeneration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28842432 DOI: 10.1096/fj.201700221RR  0.48
2017 Llovera G, Benakis C, Enzmann G, Cai R, Arzberger T, Ghasemigharagoz A, Mao X, Malik R, Lazarevic I, Liebscher S, Ertürk A, Meissner L, Vivien D, Haffner C, Plesnila N, et al. The choroid plexus is a key cerebral invasion route for T cells after stroke. Acta Neuropathologica. PMID 28762187 DOI: 10.1007/s00401-017-1758-y  0.48
2017 Labeyrie PE, Goulay R, Martinez de Lizarrondo S, Hébert M, Gauberti M, Maubert E, Delaunay B, Gory B, Signorelli F, Turjman F, Touzé E, Courthéoux P, Vivien D, Orset C. Vascular Tissue-Type Plasminogen Activator Promotes Intracranial Aneurysm Formation. Stroke. PMID 28754830 DOI: 10.1161/STROKEAHA.117.017305  0.48
2017 Louessard M, Bardou I, Lemarchand E, Thiebaut AM, Parcq J, Leprince J, Terrisse A, Carraro V, Fafournoux P, Bruhat A, Orset C, Vivien D, Ali C, Roussel BD. Activation of cell surface GRP78 decreases endoplasmic reticulum stress and neuronal death. Cell Death and Differentiation. PMID 28644439 DOI: 10.1038/cdd.2017.35  0.48
2017 Fournier AP, Quenault A, Martinez de Lizarrondo S, Gauberti M, Defer G, Vivien D, Docagne F, Macrez R. Prediction of disease activity in models of multiple sclerosis by molecular magnetic resonance imaging of P-selectin. Proceedings of the National Academy of Sciences of the United States of America. PMID 28533365 DOI: 10.1073/pnas.1619424114  0.52
2017 Martinez de Lizarrondo S, Gakuba C, Herbig BA, Repessé Y, Ali C, Denis CV, Lenting P, Touzé E, Diamond SL, Vivien D, Gauberti M. Potent Thrombolytic Effect of N-Acetylcysteine on Arterial Thrombi. Circulation. PMID 28487393 DOI: 10.1161/CIRCULATIONAHA.117.027290  0.44
2017 Briens A, Bardou I, Lebas H, Miles LA, Parmer RJ, Vivien D, Docagne F. Astrocytes regulate the balance between plasminogen activation and plasmin clearance via cell-surface actin. Cell Discovery. 3: 17001. PMID 28417010 DOI: 10.1038/celldisc.2017.1  0.52
2017 Leonetti C, Macrez R, Pruvost M, Hommet Y, Bronsard J, Fournier A, Perrigault M, Machin I, Vivien D, Clemente D, De Castro F, Maubert E, Docagne F. Tissue-type plasminogen activator exerts EGF-like chemokinetic effects on oligodendrocytes in white matter (re)myelination. Molecular Neurodegeneration. 12: 20. PMID 28231842 DOI: 10.1186/s13024-017-0160-5  0.52
2017 Quenault A, Martinez de Lizarrondo S, Etard O, Gauberti M, Orset C, Haelewyn B, Segal HC, Rothwell PM, Vivien D, Touzé E, Ali C. Molecular magnetic resonance imaging discloses endothelial activation after transient ischaemic attack. Brain : a Journal of Neurology. 140: 146-157. PMID 28031221 DOI: 10.1093/brain/aww260  0.48
2016 Macrez R, Vivien D, Docagne F. [Role of endothelial NMDA receptors in a mouse model of multiple sclerosis]. Medecine Sciences : M/S. 32: 1068-1071. PMID 28044968 DOI: 10.1051/medsci/20163212008  0.52
2016 Lesept F, Chevilley A, Jezequel J, Ladépêche L, Macrez R, Aimable M, Lenoir S, Bertrand T, Rubrecht L, Galea P, Lebouvier L, Petersen KU, Hommet Y, Maubert E, Ali C, ... ... Vivien D, et al. Tissue-type plasminogen activator controls neuronal death by raising surface dynamics of extrasynaptic NMDA receptors. Cell Death & Disease. 7: e2466. PMID 27831563 DOI: 10.1038/cddis.2016.279  0.44
2016 Hébert M, Anfray A, Chevilley A, Martinez de Lizarrondo S, Quenault A, Louessard M, Roussel BD, Obiang P, Save E, Orset C, Maubert E, Vivien D, Agin V. Distant Space Processing is Controlled by tPA-dependent NMDA Receptor Signaling in the Entorhinal Cortex. Cerebral Cortex (New York, N.Y. : 1991). PMID 27613436 DOI: 10.1093/cercor/bhw275  0.48
2016 Macrez R, Stys PK, Vivien D, Lipton SA, Docagne F. Mechanisms of glutamate toxicity in multiple sclerosis: biomarker and therapeutic opportunities. The Lancet. Neurology. 15: 1089-1102. PMID 27571160 DOI: 10.1016/S1474-4422(16)30165-X  0.52
2016 Marcos-Contreras OA, Martinez de Lizarrondo S, Bardou I, Orset C, Pruvost M, Anfray A, Frigout Y, Hommet Y, Lebouvier L, Montaner J, Vivien D, Gauberti M. Hyperfibrinolysis increases blood brain barrier permeability by a plasmin and bradykinin-dependent mechanism. Blood. PMID 27531677 DOI: 10.1182/blood-2016-03-705384  0.48
2016 Macrez R, Ortega MC, Bardou I, Mehra A, Fournier A, Van der Pol SM, Haelewyn B, Maubert E, Lesept F, Chevilley A, de Castro F, De Vries HE, Vivien D, Clemente D, Docagne F. Neuroendothelial NMDA receptors as therapeutic targets in experimental autoimmune encephalomyelitis. Brain : a Journal of Neurology. PMID 27435092 DOI: 10.1093/brain/aww172  0.52
2016 Orset C, Haelewyn B, Allan SM, Ansar S, Campos F, Cho TH, Durand A, El Amki M, Fatar M, Garcia-Yébenes I, Gauberti M, Grudzenski S, Lizasoain I, Lo E, Macrez R, ... ... Vivien D, et al. Efficacy of Alteplase in a Mouse Model of Acute Ischemic Stroke: A Retrospective Pooled Analysis. Stroke; a Journal of Cerebral Circulation. PMID 27032444 DOI: 10.1161/STROKEAHA.116.012238  0.92
2015 Maysami S, Wong R, Pradillo JM, Denes A, Dhungana H, Malm T, Koistinaho J, Orset C, Rahman M, Rubio M, Schwaninger M, Vivien D, Bath PM, Rothwell NJ, Allan SM. A cross-laboratory preclinical study on the effectiveness of interleukin-1 receptor antagonist in stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26661169 DOI: 10.1177/0271678X15606714  0.92
2015 Hébert M, Lesept F, Vivien D, Macrez R. The story of an exceptional serine protease, tissue-type plasminogen activator (tPA). Revue Neurologique. PMID 26626577 DOI: 10.1016/j.neurol.2015.10.002  0.92
2015 Chevilley A, Lesept F, Lenoir S, Ali C, Parcq J, Vivien D. Impacts of tissue-type plasminogen activator (tPA) on neuronal survival. Frontiers in Cellular Neuroscience. 9: 415. PMID 26528141 DOI: 10.3389/fncel.2015.00415  0.92
2015 Mehra A, Ali C, Parcq J, Vivien D, Docagne F. The plasminogen activation system in neuroinflammation. Biochimica Et Biophysica Acta. PMID 26493446 DOI: 10.1016/j.bbadis.2015.10.011  0.92
2015 Balossier A, Etard O, Descat C, Vivien D, Emery E. Epidural Cortical Stimulation as a Treatment for Poststroke Aphasia: A Systematic Review of the Literature and Underlying Neurophysiological Mechanisms. Neurorehabilitation and Neural Repair. PMID 26422832 DOI: 10.1177/1545968315606989  0.92
2015 Belliere J, Martinez de Lizarrondo S, Choudhury RP, Quenault A, Le Béhot A, Delage C, Chauveau D, Schanstra JP, Bascands JL, Vivien D, Gauberti M. Unmasking Silent Endothelial Activation in the Cardiovascular System Using Molecular Magnetic Resonance Imaging. Theranostics. 5: 1187-202. PMID 26379785 DOI: 10.7150/thno.11835  0.92
2015 Louessard M, Lacroix A, Martineau M, Mondielli G, Montagne A, Lesept F, Lambolez B, Cauli B, Mothet JP, Vivien D, Maubert E. Tissue Plasminogen Activator Expression Is Restricted to Subsets of Excitatory Pyramidal Glutamatergic Neurons. Molecular Neurobiology. PMID 26377106 DOI: 10.1007/s12035-015-9432-7  0.92
2015 Llovera G, Hofmann K, Roth S, Salas-Pérdomo A, Ferrer-Ferrer M, Perego C, Zanier ER, Mamrak U, Rex A, Party H, Agin V, Fauchon C, Orset C, Haelewyn B, De Simoni MG, ... ... Vivien D, et al. Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia. Science Translational Medicine. 7: 299ra121. PMID 26246166 DOI: 10.1126/scitranslmed.aaa9853  0.48
2015 Lemarchand E, Maubert E, Haelewyn B, Ali C, Rubio M, Vivien D. Stressed neurons protect themselves by a tissue-type plasminogen activator-mediated EGFR-dependent mechanism. Cell Death and Differentiation. PMID 26068590 DOI: 10.1038/cdd.2015.76  0.44
2015 Macrez R, Vivien D, Docagne F. Letter by Macrez et al. Regarding Article, "Preexisting Serum Autoantibodies Against the NMDAR Subunit NR1 Modulate Evolution of Lesion Size in Acute Ischemic Stroke". Stroke; a Journal of Cerebral Circulation. 46: e177. PMID 26022638 DOI: 10.1161/STROKEAHA.115.009670  0.92
2015 Lemarchand E, Gauberti M, Martinez de Lizarrondo S, Villain H, Repessé Y, Montagne A, Vivien D, Ali C, Rubio M. Impact of alcohol consumption on the outcome of ischemic stroke and thrombolysis: role of the hepatic clearance of tissue-type plasminogen activator. Stroke; a Journal of Cerebral Circulation. 46: 1641-50. PMID 25922513 DOI: 10.1161/STROKEAHA.114.007143  0.92
2015 Bruckert G, Vivien D, Docagne F, Roussel BD. Normalization of Reverse Transcription Quantitative PCR Data During Ageing in Distinct Cerebral Structures. Molecular Neurobiology. PMID 25663136 DOI: 10.1007/s12035-015-9114-5  0.92
2015 Joshi AU, Orset C, Engelhardt B, Baumgart-Vogt E, Gerriets T, Vivien D, Kanse SM. Deficiency of Factor VII activating protease alters the outcome of ischemic stroke in mice. The European Journal of Neuroscience. 41: 965-75. PMID 25615590 DOI: 10.1111/ejn.12830  0.48
2015 Gauberti M, Vivien D. Letter by Gauberti and Vivien regarding article, "amplification of regulatory T cells using a CD28 superagonist reduces brain damage after ischemic stroke in mice". Stroke; a Journal of Cerebral Circulation. 46: e50-1. PMID 25586834 DOI: 10.1161/STROKEAHA.114.008071  0.92
2015 Wyseure T, Rubio M, Denorme F, Martinez de Lizarrondo S, Peeters M, Gils A, De Meyer SF, Vivien D, Declerck PJ. Innovative thrombolytic strategy using a heterodimer diabody against TAFI and PAI-1 in mouse models of thrombosis and stroke. Blood. 125: 1325-32. PMID 25540192 DOI: 10.1182/blood-2014-07-588319  0.92
2015 Merino-Zamorano C, Hernández-Guillamon M, Jullienne A, Le Béhot A, Bardou I, Parés M, Fernández-Cadenas I, Giralt D, Carrera C, Ribó M, Vivien D, Ali C, Rosell A, Montaner J. NURR1 involvement in recombinant tissue-type plasminogen activator treatment complications after ischemic stroke. Stroke; a Journal of Cerebral Circulation. 46: 477-84. PMID 25503547 DOI: 10.1161/STROKEAHA.114.006826  0.92
2015 Docagne F, Parcq J, Lijnen R, Ali C, Vivien D. Understanding the functions of endogenous and exogenous tissue-type plasminogen activator during stroke. Stroke; a Journal of Cerebral Circulation. 46: 314-20. PMID 25395410 DOI: 10.1161/STROKEAHA.114.006698  0.92
2015 Ollitrault D, Legendre F, Drougard C, Briand M, Benateau H, Goux D, Chajra H, Poulain L, Hartmann D, Vivien D, Shridhar V, Baldi A, Mallein-Gerin F, Boumediene K, Demoor M, et al. BMP-2, hypoxia, and COL1A1/HtrA1 siRNAs favor neo-cartilage hyaline matrix formation in chondrocytes. Tissue Engineering. Part C, Methods. 21: 133-47. PMID 24957638 DOI: 10.1089/ten.TEC.2013.0724  0.92
2015 Llovera G, Hofmann K, Roth S, Salas-Pérdomo A, Ferrer-Ferrer M, Perego C, Zanier ER, Mamrak U, Rex A, Party H, Agin V, Fauchon C, Orset C, Haelewyn B, De Simoni MG, ... ... Vivien D, et al. Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia Science Translational Medicine. 7. DOI: 10.1126/scitranslmed.aaa9853  0.92
2015 Roussel BD, Louessard M, De Lizarrondo SM, Vivien D. The dual role of serpins and tissue-type plasminogen activator during stroke The Serpin Family: Proteins With Multiple Functions in Health and Disease. 269-292. DOI: 10.1007/978-3-319-22711-5_16  0.92
2014 Gauberti M, Montagne A, Quenault A, Vivien D. Molecular magnetic resonance imaging of brain-immune interactions. Frontiers in Cellular Neuroscience. 8: 389. PMID 25505871 DOI: 10.3389/fncel.2014.00389  0.92
2014 Scheller A, Vivien D, Kirchhoff F, Orset C, Sandu RE, Popa-Wagner A. Imaging neuroinflammation after brain injuries by ultrasensitive MRI and two-photon laser-scanning microscopy. Romanian Journal of Morphology and Embryology = Revue Roumaine De Morphologie Et Embryologie. 55: 735-43. PMID 25329099  0.92
2014 Mezzapesa A, Orset C, Plawinski L, Doeuvre L, Martinez de Lizarrondo S, Chimienti G, Vivien D, Mansour A, Matà S, Pepe G, Anglés-Cano E. Plasminogen in cerebrospinal fluid originates from circulating blood. Journal of Neuroinflammation. 11: 154. PMID 25220760 DOI: 10.1186/s12974-014-0154-y  0.92
2014 Gaberel T, Gakuba C, Goulay R, Martinez De Lizarrondo S, Hanouz JL, Emery E, Touze E, Vivien D, Gauberti M. Impaired glymphatic perfusion after strokes revealed by contrast-enhanced MRI: a new target for fibrinolysis? Stroke; a Journal of Cerebral Circulation. 45: 3092-6. PMID 25190438 DOI: 10.1161/STROKEAHA.114.006617  0.92
2014 Gaberel T, Montagne A, Lesept F, Gauberti M, Lemarchand E, Orset C, Goulay R, Bertrand T, Emery E, Vivien D. Urokinase versus Alteplase for intraventricular hemorrhage fibrinolysis. Neuropharmacology. 85: 158-65. PMID 24846802 DOI: 10.1016/j.neuropharm.2014.05.001  0.92
2014 Raoult E, Bénard M, Komuro H, Lebon A, Vivien D, Fournier A, Vaudry H, Vaudry D, Galas L. Cortical-layer-specific effects of PACAP and tPA on interneuron migration during post-natal development of the cerebellum. Journal of Neurochemistry. 130: 241-54. PMID 24646324 DOI: 10.1111/jnc.12714  0.92
2014 Lemarchant S, Pruvost M, Hébert M, Gauberti M, Hommet Y, Briens A, Maubert E, Gueye Y, Féron F, Petite D, Mersel M, do Rego JC, Vaudry H, Koistinaho J, Ali C, ... ... Vivien D, et al. tPA promotes ADAMTS-4-induced CSPG degradation, thereby enhancing neuroplasticity following spinal cord injury. Neurobiology of Disease. 66: 28-42. PMID 24576594 DOI: 10.1016/j.nbd.2014.02.005  0.92
2014 Le Behot A, Gauberti M, Martinez De Lizarrondo S, Montagne A, Lemarchand E, Repesse Y, Guillou S, Denis CV, Maubert E, Orset C, Vivien D. GpIbα-VWF blockade restores vessel patency by dissolving platelet aggregates formed under very high shear rate in mice. Blood. 123: 3354-63. PMID 24553181 DOI: 10.1182/blood-2013-12-543074  0.92
2014 Gauberti M, Martinez de Lizarrondo S, Orset C, Vivien D. Lack of secondary microthrombosis after thrombin-induced stroke in mice and non-human primates. Journal of Thrombosis and Haemostasis : Jth. 12: 409-14. PMID 24354644 DOI: 10.1111/jth.12487  0.92
2013 Rosell A, Agin V, Rahman M, Morancho A, Ali C, Koistinaho J, Wang X, Vivien D, Schwaninger M, Montaner J. Distal occlusion of the middle cerebral artery in mice: are we ready to assess long-term functional outcome? Translational Stroke Research. 4: 297-307. PMID 24323300 DOI: 10.1007/s12975-012-0234-1  0.92
2013 Lemarchant S, Pruvost M, Montaner J, Emery E, Vivien D, Kanninen K, Koistinaho J. ADAMTS proteoglycanases in the physiological and pathological central nervous system. Journal of Neuroinflammation. 10: 133. PMID 24176075 DOI: 10.1186/1742-2094-10-133  0.92
2013 Gaberel T, Gakuba C, Hebert M, Montagne A, Agin V, Rubio M, Emery E, Vivien D, Gauberti M. Intracerebral hematomas disappear on T2*-weighted images during normobaric oxygen therapy. Stroke; a Journal of Cerebral Circulation. 44: 3482-9. PMID 24105700 DOI: 10.1161/STROKEAHA.113.002045  0.92
2013 Gakuba C, Gauberti M, Vivien D. Endovascular treatment for acute ischemic stroke. The New England Journal of Medicine. 368: 2430-1. PMID 23782184 DOI: 10.1056/NEJMc1304759#SA2  0.92
2013 Gauberti M, Montagne A, Marcos-Contreras OA, Le Béhot A, Maubert E, Vivien D. Ultra-sensitive molecular MRI of vascular cell adhesion molecule-1 reveals a dynamic inflammatory penumbra after strokes. Stroke; a Journal of Cerebral Circulation. 44: 1988-96. PMID 23743972 DOI: 10.1161/STROKEAHA.111.000544  0.92
2013 Mayeur A, Duclos C, Honoré A, Gauberti M, Drouot L, do Rego JC, Bon-Mardion N, Jean L, Vérin E, Emery E, Lemarchant S, Vivien D, Boyer O, Marie JP, Guérout N. Potential of olfactory ensheathing cells from different sources for spinal cord repair. Plos One. 8: e62860. PMID 23638158 DOI: 10.1371/journal.pone.0062860  0.92
2013 Parcq J, Bertrand T, Baron AF, Hommet Y, Anglès-Cano E, Vivien D. Molecular requirements for safer generation of thrombolytics by bioengineering the tissue-type plasminogen activator A chain. Journal of Thrombosis and Haemostasis : Jth. 11: 539-46. PMID 23301636 DOI: 10.1111/jth.12128  0.92
2013 Gaberel T, Macrez R, Gauberti M, Montagne A, Hebert M, Petersen KU, Touze E, Agin V, Emery E, Ali C, Vivien D. Immunotherapy blocking the tissue plasminogen activator-dependent activation of N-methyl-D-aspartate glutamate receptors improves hemorrhagic stroke outcome. Neuropharmacology. 67: 267-71. PMID 23219658 DOI: 10.1016/j.neuropharm.2012.11.023  0.92
2013 Henry VJ, Lecointre M, Laudenbach V, Ali C, Macrez R, Jullienne A, Berezowski V, Carmeliet P, Vivien D, Marret S, Gonzalez BJ, Leroux P. High t-PA release by neonate brain microvascular endothelial cells under glutamate exposure affects neuronal fate. Neurobiology of Disease. 50: 201-8. PMID 23103420 DOI: 10.1016/j.nbd.2012.10.020  0.92
2013 Balossier A, Etard O, Descat C, Vivien D, Emery E. Epidural electrical stimulation for the treatment of chronic poststroke aphasia: still compulsory 6 years later! British Journal of Neurosurgery. 27: 246-8. PMID 22998751 DOI: 10.3109/02688697.2012.722241  0.92
2012 Kaindl AM, Degos V, Peineau S, Gouadon E, Chhor V, Loron G, Le Charpentier T, Josserand J, Ali C, Vivien D, Collingridge GL, Lombet A, Issa L, Rene F, Loeffler JP, et al. Activation of microglial N-methyl-D-aspartate receptors triggers inflammation and neuronal cell death in the developing and mature brain. Annals of Neurology. 72: 536-49. PMID 23109148 DOI: 10.1002/ana.23626  0.92
2012 Obiang P, Macrez R, Jullienne A, Bertrand T, Lesept F, Ali C, Maubert E, Vivien D, Agin V. GluN2D subunit-containing NMDA receptors control tissue plasminogen activator-mediated spatial memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 12726-34. PMID 22972996 DOI: 10.1523/JNEUROSCI.6202-11.2012  0.92
2012 Vivien D, Ali C. Traumatic brain injury: tissue-type plasminogen activator--harmful or beneficial? Nature Reviews. Neurology. 8: 538-9. PMID 22964508 DOI: 10.1038/nrneurol.2012.192  0.92
2012 El Amki M, Lerouet D, Coqueran B, Curis E, Orset C, Vivien D, Plotkine M, Marchand-Leroux C, Margaill I. Experimental modeling of recombinant tissue plasminogen activator effects after ischemic stroke. Experimental Neurology. 238: 138-44. PMID 22921458 DOI: 10.1016/j.expneurol.2012.08.005  0.92
2012 Montagne A, Hébert M, Jullienne A, Lesept F, Le Béhot A, Louessard M, Gauberti M, Orset C, Ali C, Agin V, Maubert E, Vivien D. Memantine improves safety of thrombolysis for stroke. Stroke; a Journal of Cerebral Circulation. 43: 2774-81. PMID 22879098 DOI: 10.1161/STROKEAHA.112.669374  0.92
2012 Montagne A, Gauberti M, Macrez R, Jullienne A, Briens A, Raynaud JS, Louin G, Buisson A, Haelewyn B, Docagne F, Defer G, Vivien D, Maubert E. Ultra-sensitive molecular MRI of cerebrovascular cell activation enables early detection of chronic central nervous system disorders. Neuroimage. 63: 760-70. PMID 22813950 DOI: 10.1016/j.neuroimage.2012.07.018  0.92
2012 Parcq J, Bertrand T, Montagne A, Baron AF, Macrez R, Billard JM, Briens A, Hommet Y, Wu J, Yepes M, Lijnen HR, Dutar P, Anglés-Cano E, Vivien D. Unveiling an exceptional zymogen: the single-chain form of tPA is a selective activator of NMDA receptor-dependent signaling and neurotoxicity. Cell Death and Differentiation. 19: 1983-91. PMID 22743997 DOI: 10.1038/cdd.2012.86  0.92
2012 Cassé F, Bardou I, Danglot L, Briens A, Montagne A, Parcq J, Alahari A, Galli T, Vivien D, Docagne F. Glutamate controls tPA recycling by astrocytes, which in turn influences glutamatergic signals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5186-99. PMID 22496564 DOI: 10.1523/JNEUROSCI.5296-11.2012  0.92
2012 Gauberti M, Obiang P, Guedin P, Balossier A, Gakuba C, Diependaele AS, Chazalviel L, Vivien D, Young AR, Agin V, Orset C. Thrombotic stroke in the anesthetized monkey (Macaca mulatta): characterization by MRI--a pilot study. Cerebrovascular Diseases (Basel, Switzerland). 33: 329-39. PMID 22343114 DOI: 10.1159/000335309  0.92
2012 Danglot L, Zylbersztejn K, Petkovic M, Gauberti M, Meziane H, Combe R, Champy MF, Birling MC, Pavlovic G, Bizot JC, Trovero F, Della Ragione F, Proux-Gillardeaux V, Sorg T, Vivien D, et al. Absence of TI-VAMP/Vamp7 leads to increased anxiety in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 1962-8. PMID 22323709 DOI: 10.1523/JNEUROSCI.4436-11.2012  0.92
2012 Lemarchant S, Docagne F, Emery E, Vivien D, Ali C, Rubio M. tPA in the injured central nervous system: different scenarios starring the same actor? Neuropharmacology. 62: 749-56. PMID 22079561 DOI: 10.1016/j.neuropharm.2011.10.020  0.92
2012 Balossier A, Etard O, Descat C, Vivien D, Emery E. Epidural electrical stimulation to improve chronic poststroke aphasia: a 5-year follow-up. Brain Stimulation. 5: 364-8. PMID 22037142 DOI: 10.1016/j.brs.2011.04.003  0.92
2011 Orbe J, Barrenetxe J, Rodriguez JA, Vivien D, Orset C, Parks WC, Birkland TP, Serrano R, Purroy A, Martinez de Lizarrondo S, Angles-Cano E, Páramo JA. Matrix metalloproteinase-10 effectively reduces infarct size in experimental stroke by enhancing fibrinolysis via a thrombin-activatable fibrinolysis inhibitor-mediated mechanism. Circulation. 124: 2909-19. PMID 22104553 DOI: 10.1161/CIRCULATIONAHA.111.047100  0.92
2011 Jullienne A, Montagne A, Orset C, Lesept F, Jane DE, Monaghan DT, Maubert E, Vivien D, Ali C. Selective inhibition of GluN2D-containing N-methyl-D-aspartate receptors prevents tissue plasminogen activator-promoted neurotoxicity both in vitro and in vivo. Molecular Neurodegeneration. 6: 68. PMID 21975018 DOI: 10.1186/1750-1326-6-68  0.92
2011 Raoult E, Roussel BD, Bénard M, Lefebvre T, Ravni A, Ali C, Vivien D, Komuro H, Fournier A, Vaudry H, Vaudry D, Galas L. Pituitary adenylate cyclase-activating polypeptide (PACAP) stimulates the expression and the release of tissue plasminogen activator (tPA) in neuronal cells: involvement of tPA in the neuroprotective effect of PACAP. Journal of Neurochemistry. 119: 920-31. PMID 21919910 DOI: 10.1111/j.1471-4159.2011.07486.x  0.92
2011 Rubio M, Villain H, Docagne F, Roussel BD, Ramos JA, Vivien D, Fernandez-Ruiz J, Ali C. Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults. Plos One. 6: e23690. PMID 21886913 DOI: 10.1371/journal.pone.0023690  0.92
2011 Vivien D, Gauberti M, Montagne A, Defer G, Touzé E. Impact of tissue plasminogen activator on the neurovascular unit: from clinical data to experimental evidence. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 2119-34. PMID 21878948 DOI: 10.1038/jcbfm.2011.127  0.92
2011 Gaberel T, Magheru C, Parienti JJ, Huttner HB, Vivien D, Emery E. Intraventricular fibrinolysis versus external ventricular drainage alone in intraventricular hemorrhage: a meta-analysis. Stroke; a Journal of Cerebral Circulation. 42: 2776-81. PMID 21817146 DOI: 10.1161/STROKEAHA.111.615724  0.92
2011 Gaberel T, Emery E, Vivien D. Letter by Gaberel et Al regarding article, "dose effect of intraventricular fibrinolysis in ventricular hemorrhage". Stroke; a Journal of Cerebral Circulation. 42: e548-9; author reply. PMID 21817144 DOI: 10.1161/STROKEAHA.111.627091  0.92
2011 Gakuba C, Gauberti M, Mazighi M, Defer G, Hanouz JL, Vivien D. Preclinical evidence toward the use of ketamine for recombinant tissue-type plasminogen activator-mediated thrombolysis under anesthesia or sedation. Stroke; a Journal of Cerebral Circulation. 42: 2947-9. PMID 21817137 DOI: 10.1161/STROKEAHA.111.620468  0.92
2011 Meissirel C, Ruiz de Almodovar C, Knevels E, Coulon C, Chounlamountri N, Segura I, de Rossi P, Vinckier S, Anthonis K, Deléglise B, de Mol M, Ali C, Dassonville K, Loyens E, Honnorat J, ... ... Vivien D, et al. VEGF modulates NMDA receptors activity in cerebellar granule cells through Src-family kinases before synapse formation. Proceedings of the National Academy of Sciences of the United States of America. 108: 13782-7. PMID 21804034 DOI: 10.1073/pnas.1100341108  0.92
2011 Macrez R, Obiang P, Gauberti M, Roussel B, Baron A, Parcq J, Cassé F, Hommet Y, Orset C, Agin V, Bezin L, Berrocoso TG, Petersen KU, Montaner J, Maubert E, ... Vivien D, et al. Antibodies preventing the interaction of tissue-type plasminogen activator with N-methyl-D-aspartate receptors reduce stroke damages and extend the therapeutic window of thrombolysis. Stroke; a Journal of Cerebral Circulation. 42: 2315-22. PMID 21680906 DOI: 10.1161/STROKEAHA.110.606293  0.92
2011 Roussel BD, Mysiorek C, Rouhiainen A, Jullienne A, Parcq J, Hommet Y, Culot M, Berezowski V, Cecchelli R, Rauvala H, Vivien D, Ali C. HMGB-1 promotes fibrinolysis and reduces neurotoxicity mediated by tissue plasminogen activator. Journal of Cell Science. 124: 2070-6. PMID 21610098 DOI: 10.1242/jcs.084392  0.92
2011 Correa F, Gauberti M, Parcq J, Macrez R, Hommet Y, Obiang P, Hernangómez M, Montagne A, Liot G, Guaza C, Maubert E, Ali C, Vivien D, Docagne F. Tissue plasminogen activator prevents white matter damage following stroke. The Journal of Experimental Medicine. 208: 1229-42. PMID 21576385 DOI: 10.1084/jem.20101880  0.92
2011 Macrez R, Ali C, Toutirais O, Le Mauff B, Defer G, Dirnagl U, Vivien D. Stroke and the immune system: from pathophysiology to new therapeutic strategies. The Lancet. Neurology. 10: 471-80. PMID 21511199 DOI: 10.1016/S1474-4422(11)70066-7  0.6
2011 Obiang P, Maubert E, Bardou I, Nicole O, Launay S, Bezin L, Vivien D, Agin V. Enriched housing reverses age-associated impairment of cognitive functions and tPA-dependent maturation of BDNF. Neurobiology of Learning and Memory. 96: 121-9. PMID 21440650 DOI: 10.1016/j.nlm.2011.03.004  0.92
2011 Faure C, Macrez R, Vivien D, Sahel JA, Bonnel S. Interaction study between rtPA and bevacizumab. The British Journal of Ophthalmology. 95: 743-4. PMID 20870640 DOI: 10.1136/bjo.2010.190462  0.92
2010 Macrez R, Bezin L, Le Mauff B, Ali C, Vivien D. Functional occurrence of the interaction of tissue plasminogen activator with the NR1 Subunit of N-methyl-D-aspartate receptors during stroke. Stroke; a Journal of Cerebral Circulation. 41: 2950-5. PMID 20966414 DOI: 10.1161/STROKEAHA.110.592360  0.92
2010 Doeuvre L, Plawinski L, Goux D, Vivien D, Anglés-Cano E. Plasmin on adherent cells: from microvesiculation to apoptosis. The Biochemical Journal. 432: 365-73. PMID 20846121 DOI: 10.1042/BJ20100561  0.92
2010 Baron A, Hommet Y, Cassé F, Vivien D. Tissue-type plasminogen activator induces plasmin-dependent proteolysis of intracellular neuronal nitric oxide synthase. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 102: 539-47. PMID 20636282 DOI: 10.1042/BC20100072  0.92
2010 Reijerkerk A, Kooij G, van der Pol SM, Leyen T, Lakeman K, van Het Hof B, Vivien D, de Vries HE. The NR1 subunit of NMDA receptor regulates monocyte transmigration through the brain endothelial cell barrier. Journal of Neurochemistry. 113: 447-53. PMID 20085611 DOI: 10.1111/j.1471-4159.2010.06598.x  0.92
2010 Baron A, Montagne A, Cassé F, Launay S, Maubert E, Ali C, Vivien D. NR2D-containing NMDA receptors mediate tissue plasminogen activator-promoted neuronal excitotoxicity. Cell Death and Differentiation. 17: 860-71. PMID 19911010 DOI: 10.1038/cdd.2009.172  0.92
2010 Orset C, Haelewyn B, Vivien K, Vivien D, Young AR. Rodent models of thromboembolic stroke Neuromethods. 47: 55-70. DOI: 10.1007/978-1-60761-750-1_6  0.92
2009 Vivien D, Gauberti M, Guedin P, Anglés-Cano E. [Cerebral ischemia (2), How to neutralize the neurotoxic effects of tPA]. MéDecine Sciences : M/S. 25: 855-7. PMID 19849989 DOI: 10.1051/medsci/20092510855  0.92
2009 Anglés-Cano E, Vivien D. [Cellular microparticles, potential useful biomarkers in the identification of cerebrovascular accidents]. MéDecine Sciences : M/S. 25: 843-6. PMID 19849987 DOI: 10.1051/medsci/20092510843  0.92
2009 Roussel BD, Hommet Y, Macrez R, Schulz T, Petersen KU, Berezowski V, Cecchelli R, Ali C, Vivien D. PPACK-Desmodus rotundus salivary plasminogen activator (cDSPAalpha1) prevents the passage of tissue-type plasminogen activator (rt-PA) across the blood-brain barrier and neurotoxicity. Thrombosis and Haemostasis. 102: 606-8. PMID 19718485 DOI: 10.1160/TH09-02-0114  0.92
2009 Culot M, Mysiorek C, Renftel M, Roussel BD, Hommet Y, Vivien D, Cecchelli R, Fenart L, Berezowski V, Dehouck MP, Lundquist S. Cerebrovascular protection as a possible mechanism for the protective effects of NXY-059 in preclinical models: an in vitro study. Brain Research. 1294: 144-52. PMID 19631615 DOI: 10.1016/j.brainres.2009.07.035  0.92
2009 Roussel BD, Macrez R, Jullienne A, Agin V, Maubert E, Dauphinot L, Potier MC, Plawinski L, Castel H, Hommet Y, Munuera J, Montaner J, Yepes M, Ali C, Vivien D. Age and albumin D site-binding protein control tissue plasminogen activator levels: neurotoxic impact. Brain : a Journal of Neurology. 132: 2219-30. PMID 19574439 DOI: 10.1093/brain/awp162  0.92
2009 Moldrich RX, Dauphinot L, Laffaire J, Vitalis T, Hérault Y, Beart PM, Rossier J, Vivien D, Gehrig C, Antonarakis SE, Lyle R, Potier MC. Proliferation deficits and gene expression dysregulation in Down's syndrome (Ts1Cje) neural progenitor cells cultured from neurospheres. Journal of Neuroscience Research. 87: 3143-52. PMID 19472221 DOI: 10.1002/jnr.22131  0.92
2009 Legros H, Launay S, Roussel BD, Marcou-Labarre A, Calbo S, Catteau J, Leroux P, Boyer O, Ali C, Marret S, Vivien D, Laudenbach V. Newborn- and adult-derived brain microvascular endothelial cells show age-related differences in phenotype and glutamate-evoked protease release. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 1146-58. PMID 19367295 DOI: 10.1038/jcbfm.2009.39  0.92
2009 Bardou I, Maubert E, Leprince J, Chichery R, Cocquerelle C, Launay S, Vivien D, Vaudry H, Agin V. Distribution of oxytocin-like and vasopressin-like immunoreactivities within the central nervous system of the cuttlefish, Sepia officinalis. Cell and Tissue Research. 336: 249-66. PMID 19259702 DOI: 10.1007/s00441-009-0763-4  0.92
2009 Yepes M, Roussel BD, Ali C, Vivien D. Tissue-type plasminogen activator in the ischemic brain: more than a thrombolytic. Trends in Neurosciences. 32: 48-55. PMID 18963068 DOI: 10.1016/j.tins.2008.09.006  0.92
2009 Macrez R, Gauberti M, Vivien D, Ali C. New thrombolytic agents for the treatment of ischaemic stroke | Nouveaux agents thrombolytiques pour le traitement des accidents vasculaires cérébraux Sang Thrombose Vaisseaux. 21: 453-461. DOI: 10.1684/stv.2009.0428  0.92
2008 Lebeurrier N, Launay S, Macrez R, Maubert E, Legros H, Leclerc A, Jamin SP, Picard JY, Marret S, Laudenbach V, Berger P, Sonderegger P, Ali C, di Clemente N, Vivien D. Anti-Mullerian-hormone-dependent regulation of the brain serine-protease inhibitor neuroserpin. Journal of Cell Science. 121: 3357-65. PMID 18796535 DOI: 10.1242/jcs.031872  0.92
2008 Reijerkerk A, Kooij G, van der Pol SM, Leyen T, van Het Hof B, Couraud PO, Vivien D, Dijkstra CD, de Vries HE. Tissue-type plasminogen activator is a regulator of monocyte diapedesis through the brain endothelial barrier. Journal of Immunology (Baltimore, Md. : 1950). 181: 3567-74. PMID 18714030  0.92
2008 Launay S, Maubert E, Lebeurrier N, Tennstaedt A, Campioni M, Docagne F, Gabriel C, Dauphinot L, Potier MC, Ehrmann M, Baldi A, Vivien D. HtrA1-dependent proteolysis of TGF-beta controls both neuronal maturation and developmental survival. Cell Death and Differentiation. 15: 1408-16. PMID 18551132 DOI: 10.1038/cdd.2008.82  0.92
2008 Lopez-Atalaya JP, Roussel BD, Levrat D, Parcq J, Nicole O, Hommet Y, Benchenane K, Castel H, Leprince J, To Van D, Bureau R, Rault S, Vaudry H, Petersen KU, Santos JS, ... ... Vivien D, et al. Toward safer thrombolytic agents in stroke: molecular requirements for NMDA receptor-mediated neurotoxicity. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 1212-21. PMID 18334994 DOI: 10.1038/jcbfm.2008.14  0.92
2008 Endres M, Engelhardt B, Koistinaho J, Lindvall O, Meairs S, Mohr JP, Planas A, Rothwell N, Schwaninger M, Schwab ME, Vivien D, Wieloch T, Dirnagl U. Improving outcome after stroke: overcoming the translational roadblock. Cerebrovascular Diseases (Basel, Switzerland). 25: 268-78. PMID 18292653 DOI: 10.1159/000118039  0.92
2008 Vivien D. An innovation in the treatment of CVA? | Du nouveau dans le traitement des AVC? Medecine/Sciences. 24: 710.  0.92
2007 Young AR, Ali C, Duretête A, Vivien D. Neuroprotection and stroke: time for a compromise. Journal of Neurochemistry. 103: 1302-9. PMID 17727635 DOI: 10.1111/j.1471-4159.2007.04866.x  0.92
2007 Orset C, Macrez R, Young AR, Panthou D, Angles-Cano E, Maubert E, Agin V, Vivien D. Mouse model of in situ thromboembolic stroke and reperfusion. Stroke; a Journal of Cerebral Circulation. 38: 2771-8. PMID 17702959 DOI: 10.1161/STROKEAHA.107.487520  0.92
2007 Cacquevel M, Launay S, Castel H, Benchenane K, Chéenne S, Buée L, Moons L, Delacourte A, Carmeliet P, Vivien D. Ageing and amyloid-beta peptide deposition contribute to an impaired brain tissue plasminogen activator activity by different mechanisms. Neurobiology of Disease. 27: 164-73. PMID 17566751 DOI: 10.1016/j.nbd.2007.04.004  0.92
2007 López-Atalaya JP, Roussel BD, Ali C, Maubert E, Petersen KU, Berezowski V, Cecchelli R, Orset C, Vivien D. Recombinant Desmodus rotundus salivary plasminogen activator crosses the blood-brain barrier through a low-density lipoprotein receptor-related protein-dependent mechanism without exerting neurotoxic effects. Stroke; a Journal of Cerebral Circulation. 38: 1036-43. PMID 17325305 DOI: 10.1161/01.STR.0000258100.04923.84  0.92
2007 Benchenane K, Castel H, Boulouard M, Bluthé R, Fernandez-Monreal M, Roussel BD, Lopez-Atalaya JP, Butt-Gueulle S, Agin V, Maubert E, Dantzer R, Touzani O, Dauphin F, Vivien D, Ali C. Anti-NR1 N-terminal-domain vaccination unmasks the crucial action of tPA on NMDA-receptor-mediated toxicity and spatial memory. Journal of Cell Science. 120: 578-85. PMID 17244650 DOI: 10.1242/jcs.03354  0.92
2007 Docagne F, Muñetón V, Clemente D, Ali C, Loría F, Correa F, Hernangómez M, Mestre L, Vivien D, Guaza C. Excitotoxicity in a chronic model of multiple sclerosis: Neuroprotective effects of cannabinoids through CB1 and CB2 receptor activation. Molecular and Cellular Neurosciences. 34: 551-61. PMID 17229577 DOI: 10.1016/j.mcn.2006.12.005  0.92
2007 Roussel B, Ali C, Vivien D. CVA (Cerebrovascular accidents): The challenge of our aging populations | AVC: Le challenge de nos populations vieillissantes Biofutur. 33-37.  0.92
2006 Liot G, Roussel BD, Lebeurrier N, Benchenane K, López-Atalaya JP, Vivien D, Ali C. Tissue-type plasminogen activator rescues neurones from serum deprivation-induced apoptosis through a mechanism independent of its proteolytic activity. Journal of Neurochemistry. 98: 1458-64. PMID 16800849 DOI: 10.1111/j.1471-4159.2006.03982.x  0.92
2006 Meairs S, Wahlgren N, Dirnagl U, Lindvall O, Rothwell P, Baron JC, Hossmann K, Engelhardt B, Ferro J, McCulloch J, Kaste M, Endres M, Koistinaho J, Planas A, Vivien D, et al. Stroke research priorities for the next decade--A representative view of the European scientific community. Cerebrovascular Diseases (Basel, Switzerland). 22: 75-82. PMID 16790993 DOI: 10.1159/000093098  0.92
2006 Vivien D, Ali C. Transforming growth factor-beta signalling in brain disorders. Cytokine & Growth Factor Reviews. 17: 121-8. PMID 16271500 DOI: 10.1016/j.cytogfr.2005.09.011  0.92
2005 Lesné S, Ali C, Gabriel C, Croci N, MacKenzie ET, Glabe CG, Plotkine M, Marchand-Verrecchia C, Vivien D, Buisson A. NMDA receptor activation inhibits alpha-secretase and promotes neuronal amyloid-beta production. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9367-77. PMID 16221845 DOI: 10.1523/JNEUROSCI.0849-05.2005  0.92
2005 Lebeurrier N, Liot G, Lopez-Atalaya JP, Orset C, Fernandez-Monreal M, Sonderegger P, Ali C, Vivien D. The brain-specific tissue-type plasminogen activator inhibitor, neuroserpin, protects neurons against excitotoxicity both in vitro and in vivo. Molecular and Cellular Neurosciences. 30: 552-8. PMID 16209928 DOI: 10.1016/j.mcn.2005.09.005  0.92
2005 Lin AH, Luo J, Mondshein LH, ten Dijke P, Vivien D, Contag CH, Wyss-Coray T. Global analysis of Smad2/3-dependent TGF-beta signaling in living mice reveals prominent tissue-specific responses to injury. Journal of Immunology (Baltimore, Md. : 1950). 175: 547-54. PMID 15972691  0.92
2005 Benchenane K, Berezowski V, Ali C, Fernández-Monreal M, López-Atalaya JP, Brillault J, Chuquet J, Nouvelot A, MacKenzie ET, Bu G, Cecchelli R, Touzani O, Vivien D. Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor-related protein-mediated transcytosis. Circulation. 111: 2241-9. PMID 15851587 DOI: 10.1161/01.CIR.0000163542.48611.A2  0.92
2005 Gaertner RF, Wyss-Coray T, Von Euw D, Lesné S, Vivien D, Lacombe P. Reduced brain tissue perfusion in TGF-beta 1 transgenic mice showing Alzheimer's disease-like cerebrovascular abnormalities. Neurobiology of Disease. 19: 38-46. PMID 15837559 DOI: 10.1016/j.nbd.2004.11.008  0.92
2005 Benchenane K, Berezowski V, Fernández-Monreal M, Brillault J, Valable S, Dehouck MP, Cecchelli R, Vivien D, Touzani O, Ali C. Oxygen glucose deprivation switches the transport of tPA across the blood-brain barrier from an LRP-dependent to an increased LRP-independent process. Stroke; a Journal of Cerebral Circulation. 36: 1065-70. PMID 15817895 DOI: 10.1161/01.STR.0000163050.39122.4f  0.92
2005 Lesné S, Gabriel C, Nelson DA, White E, Mackenzie ET, Vivien D, Buisson A. Akt-dependent expression of NAIP-1 protects neurons against amyloid-{beta} toxicity. The Journal of Biological Chemistry. 280: 24941-7. PMID 15797869 DOI: 10.1074/jbc.M413495200  0.92
2004 Liot G, Benchenane K, Léveillé F, López-Atalaya JP, Fernández-Monreal M, Ruocco A, Mackenzie ET, Buisson A, Ali C, Vivien D. 2,7-Bis-(4-amidinobenzylidene)-cycloheptan-1-one dihydrochloride, tPA stop, prevents tPA-enhanced excitotoxicity both in vitro and in vivo. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 24: 1153-9. PMID 15529015 DOI: 10.1097/01.WCB.0000134476.93809.75  0.92
2004 Fernández-Monreal M, López-Atalaya JP, Benchenane K, Cacquevel M, Dulin F, Le Caer JP, Rossier J, Jarrige AC, Mackenzie ET, Colloc'h N, Ali C, Vivien D. Arginine 260 of the amino-terminal domain of NR1 subunit is critical for tissue-type plasminogen activator-mediated enhancement of N-methyl-D-aspartate receptor signaling. The Journal of Biological Chemistry. 279: 50850-6. PMID 15448144 DOI: 10.1074/jbc.M407069200  0.92
2004 Cacquevel M, Lebeurrier N, Chéenne S, Vivien D. Cytokines in neuroinflammation and Alzheimer's disease. Current Drug Targets. 5: 529-34. PMID 15270199 DOI: 10.2174/1389450043345308  0.92
2004 Lebeurrier N, Vivien D, Ali C. The complexity of tissue-type plasminogen activator: can serine protease inhibitors help in stroke management? Expert Opinion On Therapeutic Targets. 8: 309-20. PMID 15268626 DOI: 10.1517/14728222.8.4.309  0.92
2004 Docagne F, Gabriel C, Lebeurrier N, Lesné S, Hommet Y, Plawinski L, Mackenzie ET, Vivien D. Sp1 and Smad transcription factors co-operate to mediate TGF-beta-dependent activation of amyloid-beta precursor protein gene transcription. The Biochemical Journal. 383: 393-9. PMID 15242331 DOI: 10.1042/BJ20040682  0.92
2004 Liot G, Gabriel C, Cacquevel M, Ali C, MacKenzie ET, Buisson A, Vivien D. Neurotrophin-3-induced PI-3 kinase/Akt signaling rescues cortical neurons from apoptosis. Experimental Neurology. 187: 38-46. PMID 15081586 DOI: 10.1016/j.expneurol.2004.01.002  0.92
2004 Fernández-Monreal M, López-Atalaya JP, Benchenane K, Léveillé F, Cacquevel M, Plawinski L, MacKenzie ET, Bu G, Buisson A, Vivien D. Is tissue-type plasminogen activator a neuromodulator? Molecular and Cellular Neurosciences. 25: 594-601. PMID 15080889 DOI: 10.1016/j.mcn.2003.11.002  0.92
2004 Benchenane K, López-Atalaya JP, Fernández-Monreal M, Touzani O, Vivien D. Equivocal roles of tissue-type plasminogen activator in stroke-induced injury. Trends in Neurosciences. 27: 155-60. PMID 15036881 DOI: 10.1016/j.tins.2003.12.011  0.92
2003 Buisson A, Lesne S, Docagne F, Ali C, Nicole O, MacKenzie ET, Vivien D. Transforming growth factor-beta and ischemic brain injury. Cellular and Molecular Neurobiology. 23: 539-50. PMID 14514014 DOI: 10.1023/A:1025072013107  0.92
2003 Docagne F, Ali C, Lesne S, Nicole O, MacKenzie ET, Buisson A, Vivien D. [Does transforming growth factor-beta (TGF-beta) act as a neuroprotective agent in cerebral ischemia?]. Journal De La SociéTé De Biologie. 197: 145-50. PMID 12910629  0.92
2003 Maillet M, Robert SJ, Cacquevel M, Gastineau M, Vivien D, Bertoglio J, Zugaza JL, Fischmeister R, Lezoualc'h F. Crosstalk between Rap1 and Rac regulates secretion of sAPPalpha. Nature Cell Biology. 5: 633-9. PMID 12819788 DOI: 10.1038/ncb1007  0.92
2003 Lahiri DK, Chen D, Vivien D, Ge YW, Greig NH, Rogers JT. Role of cytokines in the gene expression of amyloid beta-protein precursor: identification of a 5'-UTR-binding nuclear factor and its implications in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 5: 81-90. PMID 12719626  0.92
2003 Lesné S, Docagne F, Gabriel C, Liot G, Lahiri DK, Buée L, Plawinski L, Delacourte A, MacKenzie ET, Buisson A, Vivien D. Transforming growth factor-beta 1 potentiates amyloid-beta generation in astrocytes and in transgenic mice. The Journal of Biological Chemistry. 278: 18408-18. PMID 12626500 DOI: 10.1074/jbc.M300819200  0.92
2003 Valable S, Bellail A, Lesné S, Liot G, Mackenzie ET, Vivien D, Bernaudin M, Petit E. Angiopoietin-1-induced PI3-kinase activation prevents neuronal apoptosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 443-5. PMID 12514118 DOI: 10.1096/fj.02-0372fje  0.92
2003 Gabriel C, Ali C, Lesné S, Fernández-Monreal M, Docagne F, Plawinski L, MacKenzie ET, Buisson A, Vivien D. Transforming growth factor alpha-induced expression of type 1 plasminogen activator inhibitor in astrocytes rescues neurons from excitotoxicity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 277-9. PMID 12490542 DOI: 10.1096/fj.02-0403fje  0.92
2002 Docagne F, Nicole O, Gabriel C, Fernández-Monreal M, Lesné S, Ali C, Plawinski L, Carmeliet P, MacKenzie ET, Buisson A, Vivien D. Smad3-dependent induction of plasminogen activator inhibitor-1 in astrocytes mediates neuroprotective activity of transforming growth factor-beta 1 against NMDA-induced necrosis. Molecular and Cellular Neurosciences. 21: 634-44. PMID 12504596 DOI: 10.1006/mcne.2002.1206  0.92
2002 Chuquet J, Benchenane K, Liot G, Fernández-Monreal M, Toutain J, Blanchet S, Eveno E, Auffray C, Piétu G, Buisson A, Touzani O, MacKenzie ET, Vivien D. Matching gene expression with hypometabolism after cerebral ischemia in the nonhuman primate. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 1165-9. PMID 12368653 DOI: 10.1097/00004647-200210000-00002  0.92
2002 Lesné S, Blanchet S, Docagne F, Liot G, Plawinski L, MacKenzie ET, Auffray C, Buisson A, Piétu G, Vivien D. Transforming growth factor-beta1-modulated cerebral gene expression. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 1114-23. PMID 12218417 DOI: 10.1097/00004647-200209000-00009  0.92
2001 Docagne F, Colloc'h N, Bougueret V, Page M, Paput J, Tripier M, Dutartre P, MacKenzie ET, Buisson A, Komesli S, Vivien D. A soluble transforming growth factor-beta (TGF-beta ) type I receptor mimics TGF-beta responses. The Journal of Biological Chemistry. 276: 46243-50. PMID 11544249 DOI: 10.1074/jbc.M010915200  0.92
2001 Ali C, Docagne F, Nicole O, Lesné S, Toutain J, Young A, Chazalviel L, Divoux D, Caly M, Cabal P, Derlon JM, MacKenzie ET, Buisson A, Vivien D. Increased expression of transforming growth factor-beta after cerebral ischemia in the baboon: an endogenous marker of neuronal stress? Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 21: 820-7. PMID 11435794 DOI: 10.1097/00004647-200107000-00007  0.92
2001 Nicole O, Ali C, Docagne F, Plawinski L, MacKenzie ET, Vivien D, Buisson A. Neuroprotection mediated by glial cell line-derived neurotrophic factor: involvement of a reduction of NMDA-induced calcium influx by the mitogen-activated protein kinase pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 3024-33. PMID 11312287  0.92
2001 Nicole O, Docagne F, Ali C, Margaill I, Carmeliet P, MacKenzie ET, Vivien D, Buisson A. The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling. Nature Medicine. 7: 59-64. PMID 11135617 DOI: 10.1038/83358  0.92
2000 Ali C, Nicole O, Docagne F, Lesne S, MacKenzie ET, Nouvelot A, Buisson A, Vivien D. Ischemia-induced interleukin-6 as a potential endogenous neuroprotective cytokine against NMDA receptor-mediated excitotoxicity in the brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 956-66. PMID 10894179 DOI: 10.1097/00004647-200006000-00008  0.92
2000 Vivien D, Buisson A. Serine protease inhibitors: novel therapeutic targets for stroke? Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 755-64. PMID 10826525 DOI: 10.1097/00004647-200005000-00001  0.92
2000 Bernaudin M, Bellail A, Marti HH, Yvon A, Vivien D, Duchatelle I, Mackenzie ET, Petit E. Neurons and astrocytes express EPO mRNA: oxygen-sensing mechanisms that involve the redox-state of the brain. Glia. 30: 271-8. PMID 10756076 DOI: 10.1002/(SICI)1098-1136(200005)30:3<271::AID-GLIA6>3.0.CO;2-H  0.92
1999 Ruocco A, Nicole O, Docagne F, Ali C, Chazalviel L, Komesli S, Yablonsky F, Roussel S, MacKenzie ET, Vivien D, Buisson A. A transforming growth factor-beta antagonist unmasks the neuroprotective role of this endogenous cytokine in excitotoxic and ischemic brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 19: 1345-53. PMID 10598939 DOI: 10.1097/00004647-199912000-00008  0.92
1999 Docagne F, Nicole O, Marti HH, MacKenzie ET, Buisson A, Vivien D. Transforming growth factor-beta1 as a regulator of the serpins/t-PA axis in cerebral ischemia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 13: 1315-24. PMID 10428756  0.92
1998 Petitfrere E, Sartelet H, Vivien D, Varela-Nieto I, Elbtaouri H, Martiny L, Haye B. Glycosyl phosphatidylinositol (GPI)/inositolphosphate glycan (IPG): an intracellular signalling system involved in the control of thyroid cell proliferation. Biochimie. 80: 1063-7. PMID 9924986  0.32
1998 Buisson A, Nicole O, Docagne F, Sartelet H, Mackenzie ET, Vivien D. Up-regulation of a serine protease inhibitor in astrocytes mediates the neuroprotective activity of transforming growth factor beta1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 1683-91. PMID 9837858  0.92
1998 Komesli S, Vivien D, Dutartre P. Chimeric extracellular domain type II transforming growth factor (TGF)-beta receptor fused to the Fc region of human immunoglobulin as a TGF-beta antagonist. European Journal of Biochemistry / Febs. 254: 505-13. PMID 9688260  0.48
1998 Dennler S, Itoh S, Vivien D, ten Dijke P, Huet S, Gauthier JM. Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. The Embo Journal. 17: 3091-100. PMID 9606191 DOI: 10.1093/emboj/17.11.3091  0.92
1998 Vivien D, Bernaudin M, Buisson A, Divoux D, MacKenzie ET, Nouvelot A. Evidence of type I and type II transforming growth factor-beta receptors in central nervous tissues: changes induced by focal cerebral ischemia. Journal of Neurochemistry. 70: 2296-304. PMID 9603194  0.92
1993 Vivien D, Petitfrère E, Martiny L, Sartelet H, Galéra P, Haye B, Pujol JP. IPG (inositolphosphate glycan) as a cellular signal for TGF-beta 1 modulation of chondrocyte cell cycle. Journal of Cellular Physiology. 155: 437-44. PMID 8388000 DOI: 10.1002/jcp.1041550302  0.32
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