Tony Wyss-Coray - Publications

Stanford University, Palo Alto, CA 
neurodegeneration, TGF-beta, neuroinflammation

174 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 McKay A, Costa EK, Chen J, Hu CK, Chen X, Bedbrook CN, Khondker RC, Thielvoldt M, Priya Singh P, Wyss-Coray T, Brunet A. An automated feeding system for the African killifish reveals effects of dietary restriction on lifespan and allows scalable assessment of associative learning. Elife. 11. PMID 36354233 DOI: 10.7554/eLife.69008  0.755
2022 Paolicelli RC, Sierra A, Stevens B, Tremblay ME, Aguzzi A, Ajami B, Amit I, Audinat E, Bechmann I, Bennett M, Bennett F, Bessis A, Biber K, Bilbo S, Blurton-Jones M, ... ... Wyss-Coray T, et al. Microglia states and nomenclature: A field at its crossroads. Neuron. 110: 3458-3483. PMID 36327895 DOI: 10.1016/j.neuron.2022.10.020  0.418
2022 Altendorfer B, Unger MS, Poupardin R, Hoog A, Asslaber D, Gratz IK, Mrowetz H, Benedetti A, de Sousa DMB, Greil R, Egle A, Gate D, Wyss-Coray T, Aigner L. Transcriptomic Profiling Identifies CD8 T Cells in the Brain of Aged and Alzheimer's Disease Transgenic Mice as Tissue-Resident Memory T Cells. Journal of Immunology (Baltimore, Md. : 1950). 209: 1272-1285. PMID 36165202 DOI: 10.4049/jimmunol.2100737  0.689
2022 Luo J, Nguyen A, Villeda S, Zhang H, Ding Z, Lindsey D, Bieri G, Castellano JM, Beaupre GS, Wyss-Coray T. Corrigendum: Long-Term Cognitive Impairments and Pathological Alterations in a Mouse Model of Repetitive Mild Traumatic Brain Injury. Frontiers in Neurology. 13: 730576. PMID 35847232 DOI: 10.3389/fneur.2022.730576  0.742
2022 Gupta S, Moreno AJ, Wang D, Leon J, Chen C, Hahn O, Poon Y, Greenberg K, David N, Wyss-Coray T, Raftery D, Promislow DEL, Dubal DB. KL1 domain of longevity factor klotho mimics the metabolome of cognitive stimulation and enhances cognition in young and aging mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35428698 DOI: 10.1523/JNEUROSCI.2458-21.2022  0.614
2022 Vest RT, Chou CC, Zhang H, Haney MS, Li L, Laqtom NN, Chang B, Shuken S, Nguyen A, Yerra L, Yang AC, Green C, Tanga M, Abu-Remaileh M, Bassik MC, ... ... Wyss-Coray T, et al. Small molecule C381 targets the lysosome to reduce inflammation and ameliorate disease in models of neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 119: e2121609119. PMID 35259016 DOI: 10.1073/pnas.2121609119  0.578
2022 Yang AC, Vest RT, Kern F, Lee DP, Agam M, Maat CA, Losada PM, Chen MB, Schaum N, Khoury N, Toland A, Calcuttawala K, Shin H, Pálovics R, Shin A, ... ... Wyss-Coray T, et al. A human brain vascular atlas reveals diverse mediators of Alzheimer's risk. Nature. PMID 35165441 DOI: 10.1038/s41586-021-04369-3  0.694
2021 Pluvinage JV, Sun J, Claes C, Flynn RA, Haney MS, Iram T, Meng X, Lindemann R, Riley NM, Danhash E, Chadarevian JP, Tapp E, Gate D, Kondapavulur S, Cobos I, ... ... Wyss-Coray T, et al. The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C. Science Translational Medicine. 13: eabg2919. PMID 34851695 DOI: 10.1126/scitranslmed.abg2919  0.61
2021 Gate D, Tapp E, Leventhal O, Shahid M, Nonninger TJ, Yang AC, Strempfl K, Unger MS, Fehlmann T, Oh H, Channappa D, Henderson VW, Keller A, Aigner L, Galasko DR, ... ... Wyss-Coray T, et al. CD4 T cells contribute to neurodegeneration in Lewy body dementia. Science (New York, N.Y.). eabf7266. PMID 34648304 DOI: 10.1126/science.abf7266  0.627
2021 Yang AC, Kern F, Losada PM, Agam MR, Maat CA, Schmartz GP, Fehlmann T, Stein JA, Schaum N, Lee DP, Calcuttawala K, Vest RT, Berdnik D, Lu N, Hahn O, ... ... Wyss-Coray T, et al. Publisher Correction: Dysregulation of brain and choroid plexus cell types in severe COVID-19. Nature. PMID 34625744 DOI: 10.1038/s41586-021-04080-3  0.651
2021 Yang AC, Kern F, Losada PM, Agam MR, Maat CA, Schmartz GP, Fehlmann T, Stein JA, Schaum N, Lee DP, Calcuttawala K, Vest RT, Berdnik D, Lu N, Hahn O, ... ... Wyss-Coray T, et al. Dysregulation of brain and choroid plexus cell types in severe COVID-19. Nature. PMID 34153974 DOI: 10.1038/s41586-021-03710-0  0.691
2021 Oh H, Leventhal O, Channappa D, Henderson VW, Wyss-Coray T, Lehallier B, Gate D. Methods to investigate intrathecal adaptive immunity in neurodegeneration. Molecular Neurodegeneration. 16: 3. PMID 33482851 DOI: 10.1186/s13024-021-00423-w  0.671
2020 Marschallinger J, Iram T, Zardeneta M, Lee SE, Lehallier B, Haney MS, Pluvinage JV, Mathur V, Hahn O, Morgens DW, Kim J, Tevini J, Felder TK, Wolinski H, Bertozzi CR, ... ... Wyss-Coray T, et al. Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain. Nature Neuroscience. PMID 32719564 DOI: 10.1038/s41593-020-0682-y  0.568
2020 Brigger D, Riether C, van Brummelen R, Mosher KI, Shiu A, Ding Z, Zbären N, Gasser P, Guntern P, Yousef H, Castellano JM, Storni F, Graff-Radford N, Britschgi M, Grandgirard D, ... ... Wyss-Coray T, et al. Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age. Nature Metabolism. PMID 32694825 DOI: 10.1038/s42255-020-0228-3  0.782
2020 Schaum N, Lehallier B, Hahn O, Pálovics R, Hosseinzadeh S, Lee SE, Sit R, Lee DP, Losada PM, Zardeneta ME, Fehlmann T, Webber JT, McGeever A, Calcuttawala K, Zhang H, ... ... Wyss-Coray T, et al. Ageing hallmarks exhibit organ-specific temporal signatures. Nature. PMID 32669715 DOI: 10.1038/S41586-020-2499-Y  0.335
2020 Yang AC, Stevens MY, Chen MB, Lee DP, Stähli D, Gate D, Contrepois K, Chen W, Iram T, Zhang L, Vest RT, Chaney A, Lehallier B, Olsson N, du Bois H, ... ... Wyss-Coray T, et al. Physiological blood-brain transport is impaired with age by a shift in transcytosis. Nature. PMID 32612231 DOI: 10.1038/S41586-020-2453-Z  0.701
2020 Johnson AA, Shokhirev MN, Wyss-Coray T, Lehallier B. Systematic review and analysis of human proteomics aging studies unveils a novel proteomic aging clock and identifies key processes that change with age. Ageing Research Reviews. 101070. PMID 32311500 DOI: 10.1016/J.Arr.2020.101070  0.325
2020 Chen MB, Yang AC, Yousef H, Lee D, Chen W, Schaum N, Lehallier B, Quake SR, Wyss-Coray T. Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory Cues. Cell Reports. 30: 4418-4432.e4. PMID 32234477 DOI: 10.1016/J.Celrep.2020.03.012  0.407
2020 Pluvinage JV, Wyss-Coray T. Author Correction: Systemic factors as mediators of brain homeostasis, ageing and neurodegeneration. Nature Reviews. Neuroscience. PMID 32203300 DOI: 10.1038/s41583-020-0293-3  0.327
2020 Marschallinger J, Iram T, Zardeneta M, Lee SE, Lehallier B, Haney MS, Pluvinage JV, Mathur V, Hahn O, Morgens DW, Kim J, Tevini J, Felder TK, Wolinski H, Bertozzi CR, ... ... Wyss-Coray T, et al. Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain. Nature Neuroscience. PMID 32005940 DOI: 10.1038/S41593-020-0595-9  0.608
2020 Marschallinger J, Iram T, Zardeneta M, Lee SE, Lehallier B, Haney MS, Pluvinage JV, Mathur V, Hahn O, Morgens DW, Kim J, Tevini J, Felder TK, Wolinski H, Bertozzi CR, ... ... Wyss-Coray T, et al. Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain. Nature Neuroscience. PMID 31959936 DOI: 10.1038/S41593-019-0566-1  0.64
2020 Gate D, Saligrama N, Leventhal O, Yang AC, Unger MS, Middeldorp J, Chen K, Lehallier B, Channappa D, De Los Santos MB, McBride A, Pluvinage J, Elahi F, Tam GK, Kim Y, ... ... Wyss-Coray T, et al. Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease. Nature. PMID 31915375 DOI: 10.1038/S41586-019-1895-7  0.709
2020 Pluvinage JV, Wyss-Coray T. Systemic factors as mediators of brain homeostasis, ageing and neurodegeneration. Nature Reviews. Neuroscience. 21: 93-102. PMID 31913356 DOI: 10.1038/s41583-019-0255-9  0.415
2019 Lehallier B, Gate D, Schaum N, Nanasi T, Lee SE, Yousef H, Moran Losada P, Berdnik D, Keller A, Verghese J, Sathyan S, Franceschi C, Milman S, Barzilai N, Wyss-Coray T. Undulating changes in human plasma proteome profiles across the lifespan. Nature Medicine. 25: 1843-1850. PMID 31806903 DOI: 10.1038/S41591-019-0673-2  0.7
2019 Bellozi PMQ, Gomes GF, Machado da Silva MC, Vieira de Assis Lima I, Batista CRÁ, de Oliveira Carneiro Junior W, Dória JG, Vieira ÉLM, Vieira RP, de Freitas RP, Ferreira CN, Candelario-Jalil E, Wyss-Coray T, Ribeiro FM, de Oliveira ACP. A positive allosteric modulator of mGluR5 promotes neuroprotective effects in mice models of Alzheimer's disease. Neuropharmacology. 107785. PMID 31541651 DOI: 10.1016/J.Neuropharm.2019.107785  0.438
2019 Dulken BW, Buckley MT, Navarro Negredo P, Saligrama N, Cayrol R, Leeman DS, George BM, Boutet SC, Hebestreit K, Pluvinage JV, Wyss-Coray T, Weissman IL, Vogel H, Davis MM, Brunet A. Single-cell analysis reveals T cell infiltration in old neurogenic niches. Nature. PMID 31270459 DOI: 10.1038/S41586-019-1362-5  0.548
2019 Iram T, Keller A, Wyss-Coray T. An 80,000-Piece Puzzle of Alzheimer's Disease. Immunity. 50: 1349-1351. PMID 31216459 DOI: 10.1016/j.immuni.2019.05.016  0.385
2019 Yousef H, Czupalla CJ, Lee D, Chen MB, Burke AN, Zera KA, Zandstra J, Berber E, Lehallier B, Mathur V, Nair RV, Bonanno LN, Yang AC, Peterson T, Hadeiba H, ... ... Wyss-Coray T, et al. Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1. Nature Medicine. PMID 31086348 DOI: 10.1038/S41591-019-0440-4  0.768
2019 Pluvinage JV, Haney MS, Smith BAH, Sun J, Iram T, Bonanno L, Li L, Lee DP, Morgens DW, Yang AC, Shuken SR, Gate D, Scott M, Khatri P, Luo J, ... ... Wyss-Coray T, et al. CD22 blockade restores homeostatic microglial phagocytosis in ageing brains. Nature. PMID 30944478 DOI: 10.1038/S41586-019-1088-4  0.779
2019 Lehallier B, Gate D, Schaum N, Nanasi T, Lee SE, Yousef H, Berdnik D, Franceschi C, Wyss-Coray T. UNDULATIONS OF THE PLASMA PROTEOME DEFINE DISTINCT STAGES OF HUMAN LIFESPAN AND REVEAL ACCELERATED AGING IN ALZHEIMER’S DISEASE Alzheimer's & Dementia. 15: P1628. DOI: 10.1016/J.Jalz.2019.06.4862  0.68
2019 Gate D, Saligrama N, Yang A, Middeldorp J, Levanthal O, Chen K, Lehallier B, McBride A, Channappa D, Tam G, Kim Y, Greicius MD, Wagner AD, Davis M, Wyss-Coray T. O4-09-06: CLONALLY EXPANDED CD8 T CELLS PATROL ALZHEIMER'S CEREBROSPINAL FLUID Alzheimer's & Dementia. 15: P1257-P1258. DOI: 10.1016/J.Jalz.2019.06.4793  0.661
2019 Vest R, Haney M, Zhang H, Li L, Wyss-Coray T, Luo J. P3‐048: Anti‐Inflammatory Small Molecule Sri‐011381 For The Treatment Of Neurodegeneration And Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3074  0.33
2019 Nanasi T, Ulbert I, Wyss-Coray T, Lehallier B. Identification of transcriptomic changes during brain aging and neurodegeneration using interactome-based Support Vector Machine model Ibro Reports. 6: S405. DOI: 10.1016/J.Ibror.2019.07.1291  0.314
2018 Li Q, Cheng Z, Zhou L, Darmanis S, Neff NF, Okamoto J, Gulati G, Bennett ML, Sun LO, Clarke LE, Marschallinger J, Yu G, Quake SR, Wyss-Coray T, Barres BA. Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing. Neuron. PMID 30606613 DOI: 10.1016/J.Neuron.2018.12.006  0.583
2018 Bieri G, Lucin KM, O'Brien CE, Zhang H, Villeda SA, Wyss-Coray T. Proteolytic cleavage of Beclin 1 exacerbates neurodegeneration. Molecular Neurodegeneration. 13: 68. PMID 30594228 DOI: 10.1186/S13024-018-0302-4  0.717
2018 Sha SJ, Deutsch GK, Tian L, Richardson K, Coburn M, Gaudioso JL, Marcal T, Solomon E, Boumis A, Bet A, Mennes M, van Oort E, Beckmann CF, Braithwaite SP, Jackson S, ... ... Wyss-Coray T, et al. Safety, Tolerability, and Feasibility of Young Plasma Infusion in the Plasma for Alzheimer Symptom Amelioration Study: A Randomized Clinical Trial. Jama Neurology. PMID 30383097 DOI: 10.1001/Jamaneurol.2018.3288  0.352
2018 Sahbaie P, Tajerian M, Yang P, Irvine KA, Huang TT, Luo J, Wyss-Coray T, Clark JD. Nociceptive and Cognitive Changes in a Murine Model of Polytrauma. The Journal of Pain : Official Journal of the American Pain Society. PMID 29964216 DOI: 10.1016/J.Jpain.2018.06.004  0.705
2018 Yang AC, du Bois H, Olsson N, Gate D, Lehallier B, Berdnik D, Brewer KD, Bertozzi CR, Elias JE, Wyss-Coray T. Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics. Journal of the American Chemical Society. PMID 29775058 DOI: 10.1021/Jacs.8B03074  0.66
2017 Mathur V, Burai R, Vest RT, Bonanno LN, Lehallier B, Zardeneta ME, Mistry KN, Do D, Marsh SE, Abud EM, Blurton-Jones M, Li L, Lashuel HA, Wyss-Coray T. Activation of the STING-Dependent Type I Interferon Response Reduces Microglial Reactivity and Neuroinflammation. Neuron. 96: 1290-1302.e6. PMID 29268096 DOI: 10.1016/J.Neuron.2017.11.032  0.317
2017 Castellano JM, Mosher KI, Abbey RJ, McBride AA, James ML, Berdnik D, Shen JC, Zou B, Xie XS, Tingle M, Hinkson IV, Angst MS, Wyss-Coray T. Human umbilical cord plasma proteins revitalize hippocampal function in aged mice. Nature. PMID 28424512 DOI: 10.1038/Nature22067  0.637
2017 Tesseur I, Nguyen A, Chang B, Li L, Woodling NS, Wyss-Coray T, Luo J. Deficiency in neuronal TGF-β signaling leads to nigrostriatal degeneration and activation of TGF-β signaling protects against MPTP neurotoxicity in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28363982 DOI: 10.1523/Jneurosci.2952-16.2017  0.692
2017 Zhang Z, Takeda-Uchimura Y, Foyez T, Ohtake-Niimi S, Narentuya, Akatsu H, Nishitsuji K, Michikawa M, Wyss-Coray T, Kadomatsu K, Uchimura K. Deficiency of a sulfotransferase for sialic acid-modified glycans mitigates Alzheimer's pathology. Proceedings of the National Academy of Sciences of the United States of America. PMID 28320965 DOI: 10.1073/pnas.1615036114  0.439
2017 Czirr E, Castello NA, Mosher KI, Castellano JM, Hinkson IV, Lucin KM, Baeza-Raja B, Ryu JK, Li L, Farina SN, Belichenko NP, Longo FM, Akassoglou K, Britschgi M, Cirrito JR, ... Wyss-Coray T, et al. Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity. The Journal of Experimental Medicine. PMID 28298456 DOI: 10.1084/Jem.20162011  0.811
2016 Wyss-Coray T. Ageing, neurodegeneration and brain rejuvenation. Nature. 539: 180-186. PMID 27830812 DOI: 10.1038/nature20411  0.379
2016 Middeldorp J, Lehallier B, Villeda SA, Miedema SS, Evans E, Czirr E, Zhang H, Luo J, Stan T, Mosher KI, Masliah E, Wyss-Coray T. Preclinical Assessment of Young Blood Plasma for Alzheimer Disease. Jama Neurology. PMID 27598869 DOI: 10.1001/Jamaneurol.2016.3185  0.8
2016 Castellano JM, Palner M, Li SB, Freeman GM, Nguyen A, Shen B, Stan T, Mosher KI, Chin FT, de Lecea L, Luo J, Wyss-Coray T. In vivo assessment of behavioral recovery and circulatory exchange in the peritoneal parabiosis model. Scientific Reports. 6: 29015. PMID 27364522 DOI: 10.1038/Srep29015  0.591
2016 Zhang XD, Wang H, Antaris AL, Li L, Diao S, Ma R, Nguyen A, Hong G, Ma Z, Wang J, Zhu S, Castellano JM, Wyss-Coray T, Liang Y, Luo J, et al. Traumatic Brain Injury Imaging in the Second Near-Infrared Window with a Molecular Fluorophore. Advanced Materials (Deerfield Beach, Fla.). PMID 27253071 DOI: 10.1002/Adma.201600706  0.559
2016 Jaeger PA, Lucin KM, Britschgi M, Vardarajan B, Huang RP, Kirby ED, Abbey R, Boeve BF, Boxer AL, Farrer LA, Finch N, Graff-Radford NR, Head E, Hofree M, Huang R, ... ... Wyss-Coray T, et al. Erratum to: Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain. Molecular Neurodegeneration. 11: 42. PMID 27216421 DOI: 10.1186/S13024-016-0105-4  0.774
2016 Jaeger PA, Lucin KM, Britschgi M, Vardarajan B, Huang RP, Kirby ED, Abbey R, Boeve BF, Boxer AL, Farrer LA, Finch N, Graff-Radford NR, Head E, Hoffree M, Huang R, ... ... Wyss-Coray T, et al. Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain. Molecular Neurodegeneration. 11: 31. PMID 27112350 DOI: 10.1186/S13024-016-0095-2  0.799
2015 O'Brien CE, Bonanno L, Zhang H, Wyss-Coray T. Beclin 1 regulates neuronal transforming growth factor-β signaling by mediating recycling of the type I receptor ALK5. Molecular Neurodegeneration. 10: 69. PMID 26692002 DOI: 10.1186/s13024-015-0065-0  0.318
2015 Lehallier B, Essioux L, Gayan J, Alexandridis R, Nikolcheva T, Wyss-Coray T, Britschgi M. Combined Plasma and Cerebrospinal Fluid Signature for the Prediction of Midterm Progression From Mild Cognitive Impairment to Alzheimer Disease. Jama Neurology. 1-10. PMID 26659895 DOI: 10.1001/Jamaneurol.2015.3135  0.678
2015 DeCarolis NA, Kirby ED, Wyss-Coray T, Palmer TD. The Role of the Microenvironmental Niche in Declining Stem-Cell Functions Associated with Biological Aging. Cold Spring Harbor Perspectives in Medicine. 5. PMID 26627453 DOI: 10.1101/cshperspect.a025874  0.585
2015 Prokop S, Miller KR, Drost N, Handrick S, Mathur V, Luo J, Wegner A, Wyss-Coray T, Heppner FL. Impact of peripheral myeloid cells on amyloid-β pathology in Alzheimer's disease-like mice. The Journal of Experimental Medicine. 212: 1811-8. PMID 26458768 DOI: 10.1084/Jem.20150479  0.716
2015 Castellano JM, Kirby ED, Wyss-Coray T. Blood-Borne Revitalization of the Aged Brain. Jama Neurology. PMID 26237737 DOI: 10.1001/Jamaneurol.2015.1616  0.732
2015 Smith LK, He Y, Park JS, Bieri G, Snethlage CE, Lin K, Gontier G, Wabl R, Plambeck KE, Udeochu J, Wheatley EG, Bouchard J, Eggel A, Narasimha R, Grant JL, ... ... Wyss-Coray T, et al. β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis. Nature Medicine. PMID 26147761 DOI: 10.1038/Nm.3898  0.793
2015 Schachtrup C, Ryu JK, Mammadzada K, Khan AS, Carlton PM, Perez A, Christian F, Le Moan N, Vagena E, Baeza-Raja B, Rafalski V, Chan JP, Nitschke R, Houslay MD, Ellisman MH, ... Wyss-Coray T, et al. Nuclear pore complex remodeling by p75(NTR) cleavage controls TGF-β signaling and astrocyte functions. Nature Neuroscience. PMID 26120963 DOI: 10.1038/Nn.4054  0.652
2015 Shieh P, Dien VT, Beahm BJ, Castellano JM, Wyss-Coray T, Bertozzi CR. CalFluors: A Universal Motif for Fluorogenic Azide Probes across the Visible Spectrum. Journal of the American Chemical Society. 137: 7145-51. PMID 25902190 DOI: 10.1021/Jacs.5B02383  0.546
2015 Endo F, Komine O, Fujimori-Tonou N, Katsuno M, Jin S, Watanabe S, Sobue G, Dezawa M, Wyss-Coray T, Yamanaka K. Astrocyte-derived TGF-β1 accelerates disease progression in ALS mice by interfering with the neuroprotective functions of microglia and T cells. Cell Reports. 11: 592-604. PMID 25892237 DOI: 10.1016/J.Celrep.2015.03.053  0.345
2015 Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, Jacobs AH, Wyss-Coray T, Vitorica J, Ransohoff RM, Herrup K, Frautschy SA, Finsen B, Brown GC, Verkhratsky A, et al. Neuroinflammation in Alzheimer's disease. The Lancet. Neurology. 14: 388-405. PMID 25792098 DOI: 10.1016/S1474-4422(15)70016-5  0.727
2015 Kirby ED, Kuwahara AA, Messer RL, Wyss-Coray T. Adult hippocampal neural stem and progenitor cells regulate the neurogenic niche by secreting VEGF. Proceedings of the National Academy of Sciences of the United States of America. 112: 4128-33. PMID 25775598 DOI: 10.1073/pnas.1422448112  0.564
2014 Kennedy BK, Berger SL, Brunet A, Campisi J, Cuervo AM, Epel ES, Franceschi C, Lithgow GJ, Morimoto RI, Pessin JE, Rando TA, Richardson A, Schadt EE, Wyss-Coray T, Sierra F. Geroscience: linking aging to chronic disease. Cell. 159: 709-13. PMID 25417146 DOI: 10.1016/J.Cell.2014.10.039  0.541
2014 Li WW, Guo TZ, Shi X, Czirr E, Stan T, Sahbaie P, Wyss-Coray T, Kingery WS, Clark JD. Autoimmunity contributes to nociceptive sensitization in a mouse model of complex regional pain syndrome. Pain. 155: 2377-89. PMID 25218828 DOI: 10.1016/J.Pain.2014.09.007  0.697
2014 Baruch K, Deczkowska A, David E, Castellano JM, Miller O, Kertser A, Berkutzki T, Barnett-Itzhaki Z, Bezalel D, Wyss-Coray T, Amit I, Schwartz M. Aging. Aging-induced type I interferon response at the choroid plexus negatively affects brain function. Science (New York, N.Y.). 346: 89-93. PMID 25147279 DOI: 10.1126/Science.1252945  0.634
2014 Mak AC, Pullinger CR, Tang LF, Wong JS, Deo RC, Schwarz JM, Gugliucci A, Movsesyan I, Ishida BY, Chu C, Poon A, Kim P, Stock EO, Schaefer EJ, Asztalos BF, ... ... Wyss-Coray T, et al. Effects of the absence of apolipoprotein e on lipoproteins, neurocognitive function, and retinal function. Jama Neurology. 71: 1228-36. PMID 25111166 DOI: 10.1001/Jamaneurol.2014.2011  0.541
2014 Kleinberger G, Yamanishi Y, Suárez-Calvet M, Czirr E, Lohmann E, Cuyvers E, Struyfs H, Pettkus N, Wenninger-Weinzierl A, Mazaheri F, Tahirovic S, Lleó A, Alcolea D, Fortea J, Willem M, ... ... Wyss-Coray T, et al. TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis. Science Translational Medicine. 6: 243ra86. PMID 24990881 DOI: 10.1126/Scitranslmed.3009093  0.735
2014 Nguyen TV, Shen L, Vander Griend L, Quach LN, Belichenko NP, Saw N, Yang T, Shamloo M, Wyss-Coray T, Massa SM, Longo FM. Small molecule p75NTR ligands reduce pathological phosphorylation and misfolding of tau, inflammatory changes, cholinergic degeneration, and cognitive deficits in AβPP(L/S) transgenic mice. Journal of Alzheimer's Disease : Jad. 42: 459-83. PMID 24898660 DOI: 10.3233/Jad-140036  0.416
2014 He Y, Zhang H, Yung A, Villeda SA, Jaeger PA, Olayiwola O, Fainberg N, Wyss-Coray T. ALK5-dependent TGF-β signaling is a major determinant of late-stage adult neurogenesis. Nature Neuroscience. 17: 943-52. PMID 24859199 DOI: 10.1038/Nn.3732  0.794
2014 Villeda SA, Plambeck KE, Middeldorp J, Castellano JM, Mosher KI, Luo J, Smith LK, Bieri G, Lin K, Berdnik D, Wabl R, Udeochu J, Wheatley EG, Zou B, Simmons DA, ... ... Wyss-Coray T, et al. Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice. Nature Medicine. 20: 659-63. PMID 24793238 DOI: 10.1038/Nm.3569  0.781
2014 Luo J, Nguyen A, Villeda S, Zhang H, Ding Z, Lindsey D, Bieri G, Castellano JM, Beaupre GS, Wyss-Coray T. Long-term cognitive impairments and pathological alterations in a mouse model of repetitive mild traumatic brain injury. Frontiers in Neurology. 5: 12. PMID 24550885 DOI: 10.3389/Fneur.2014.00012  0.767
2014 Eggel A, Wyss-Coray T. A revival of parabiosis in biomedical research. Swiss Medical Weekly. 144: w13914. PMID 24496774 DOI: 10.4414/smw.2014.13914  0.332
2014 Ding Z, Mathur V, Ho PP, James ML, Lucin KM, Hoehne A, Alabsi H, Gambhir SS, Steinman L, Luo J, Wyss-Coray T. Antiviral drug ganciclovir is a potent inhibitor of microglial proliferation and neuroinflammation. The Journal of Experimental Medicine. 211: 189-98. PMID 24493798 DOI: 10.1084/Jem.20120696  0.33
2014 Kerchner GA, Berdnik D, Shen JC, Bernstein JD, Fenesy MC, Deutsch GK, Wyss-Coray T, Rutt BK. APOE ε4 worsens hippocampal CA1 apical neuropil atrophy and episodic memory. Neurology. 82: 691-7. PMID 24453080 DOI: 10.1212/WNL.0000000000000154  0.303
2014 Mosher KI, Wyss-Coray T. Microglial dysfunction in brain aging and Alzheimer's disease. Biochemical Pharmacology. 88: 594-604. PMID 24445162 DOI: 10.1016/j.bcp.2014.01.008  0.446
2014 O'Brien CE, Wyss-Coray T. Sorting through the roles of beclin 1 in microglia and neurodegeneration. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 9: 285-92. PMID 24385262 DOI: 10.1007/s11481-013-9519-8  0.398
2014 Henriksen K, O'Bryant SE, Hampel H, Trojanowski JQ, Montine TJ, Jeromin A, Blennow K, Lönneborg A, Wyss-Coray T, Soares H, Bazenet C, Sjögren M, Hu W, Lovestone S, Karsdal MA, et al. The future of blood-based biomarkers for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 115-31. PMID 23850333 DOI: 10.1016/J.Jalz.2013.01.013  0.354
2014 Deczkowska A, Baruch K, David E, Castellano JM, Miller O, Kertser A, Berkutzki T, Barnett-Itzhaki Z, Bezalel D, Wyss-coray T, Amit I, Schwartz M. Aging-induced immunological signature of the brain's choroid plexus negatively regulates neurogenesis and cognitive function Journal of Neuroimmunology. 275: 124. DOI: 10.1016/J.Jneuroim.2014.08.331  0.602
2014 Kerchner GA, Czirr E, Bernstein JD, Wyss-Coray T, Rutt BK. P1-265: CEREBROSPINAL FLUID TAU, BUT NOT AMYLOID, TRACKS ATROPHY IN ALZHEIMER'S-VULNERABLE HIPPOCAMPAL SUBFIELDS Alzheimer's & Dementia. 10: P406-P406. DOI: 10.1016/j.jalz.2014.05.505  0.706
2014 Kerchner GA, Czirr E, Bernstein JD, Wyss-Coray T, Rutt BK. IC-P-166: CEREBROSPINAL FLUID TAU, BUT NOT AMYLOID, TRACKS ATROPHY IN ALZHEIMER-VULNERABLE HIPPOCAMPAL SUBFIELDS Alzheimer's & Dementia. 10: P93-P93. DOI: 10.1016/J.Jalz.2014.05.173  0.716
2013 Lucin KM, O'Brien CE, Bieri G, Czirr E, Mosher KI, Abbey RJ, Mastroeni DF, Rogers J, Spencer B, Masliah E, Wyss-Coray T. Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease. Neuron. 79: 873-86. PMID 24012002 DOI: 10.1016/J.Neuron.2013.06.046  0.757
2013 Martinez-Canabal A, Wheeler AL, Sarkis D, Lerch JP, Lu WY, Buckwalter MS, Wyss-Coray T, Josselyn SA, Frankland PW. Chronic over-expression of TGFβ1 alters hippocampal structure and causes learning deficits. Hippocampus. 23: 1198-211. PMID 23804429 DOI: 10.1002/Hipo.22159  0.696
2013 Knowles JK, Simmons DA, Nguyen TV, Vander Griend L, Xie Y, Zhang H, Yang T, Pollak J, Chang T, Arancio O, Buckwalter MS, Wyss-Coray T, Massa SM, Longo FM. Small molecule p75NTR ligand prevents cognitive deficits and neurite degeneration in an Alzheimer's mouse model. Neurobiology of Aging. 34: 2052-63. PMID 23545424 DOI: 10.1016/J.Neurobiolaging.2013.02.015  0.702
2013 Miller ZA, Rankin KP, Graff-Radford NR, Takada LT, Sturm VE, Cleveland CM, Criswell LA, Jaeger PA, Stan T, Heggeli KA, Hsu SC, Karydas A, Khan BK, Grinberg LT, Gorno-Tempini ML, ... ... Wyss-Coray T, et al. TDP-43 frontotemporal lobar degeneration and autoimmune disease. Journal of Neurology, Neurosurgery, and Psychiatry. 84: 956-62. PMID 23543794 DOI: 10.1136/Jnnp-2012-304644  0.759
2013 Semar S, Klotz M, Letiembre M, Van Ginneken C, Braun A, Jost V, Bischof M, Lammers WJ, Liu Y, Fassbender K, Wyss-Coray T, Kirchhoff F, Schäfer KH. Changes of the enteric nervous system in amyloid-β protein precursor transgenic mice correlate with disease progression. Journal of Alzheimer's Disease : Jad. 36: 7-20. PMID 23531500 DOI: 10.3233/JAD-120511  0.36
2013 Luo J, Elwood F, Britschgi M, Villeda S, Zhang H, Ding Z, Zhu L, Alabsi H, Getachew R, Narasimhan R, Wabl R, Fainberg N, James ML, Wong G, Relton J, ... ... Wyss-Coray T, et al. Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival. The Journal of Experimental Medicine. 210: 157-72. PMID 23296467 DOI: 10.1084/Jem.20120412  0.798
2013 Villeda SA, Wyss-Coray T. The circulatory systemic environment as a modulator of neurogenesis and brain aging. Autoimmunity Reviews. 12: 674-7. PMID 23201925 DOI: 10.1016/J.Autrev.2012.10.014  0.709
2012 Mosher KI, Andres RH, Fukuhara T, Bieri G, Hasegawa-Moriyama M, He Y, Guzman R, Wyss-Coray T. Neural progenitor cells regulate microglia functions and activity. Nature Neuroscience. 15: 1485-7. PMID 23086334 DOI: 10.1038/nn.3233  0.328
2012 Britschgi M, Takeda-Uchimura Y, Rockenstein E, Johns H, Masliah E, Wyss-Coray T. Deficiency of terminal complement pathway inhibitor promotes neuronal tau pathology and degeneration in mice. Journal of Neuroinflammation. 9: 220. PMID 22989354 DOI: 10.1186/1742-2094-9-220  0.708
2012 Faizi M, Bader PL, Saw N, Nguyen TV, Beraki S, Wyss-Coray T, Longo FM, Shamloo M. Thy1-hAPP(Lond/Swe+) mouse model of Alzheimer's disease displays broad behavioral deficits in sensorimotor, cognitive and social function. Brain and Behavior. 2: 142-54. PMID 22574282 DOI: 10.1002/Brb3.41  0.388
2012 Czirr E, Wyss-Coray T. The immunology of neurodegeneration. The Journal of Clinical Investigation. 122: 1156-63. PMID 22466657 DOI: 10.1172/Jci58656  0.726
2012 Hosono-Fukao T, Ohtake-Niimi S, Hoshino H, Britschgi M, Akatsu H, Hossain MM, Nishitsuji K, van Kuppevelt TH, Kimata K, Michikawa M, Wyss-Coray T, Uchimura K. Heparan sulfate subdomains that are degraded by Sulf accumulate in cerebral amyloid ß plaques of Alzheimer's disease: evidence from mouse models and patients. The American Journal of Pathology. 180: 2056-67. PMID 22429964 DOI: 10.1016/J.Ajpath.2012.01.015  0.71
2012 Wyss-Coray T, Rogers J. Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature. Cold Spring Harbor Perspectives in Medicine. 2: a006346. PMID 22315714 DOI: 10.1101/cshperspect.a006346  0.384
2012 Lifshitz V, Weiss R, Benromano T, Kfir E, Blumenfeld-Katzir T, Tempel-Brami C, Assaf Y, Xia W, Wyss-Coray T, Weiner HL, Frenkel D. Immunotherapy of cerebrovascular amyloidosis in a transgenic mouse model. Neurobiology of Aging. 33: 432.e1-432.e13. PMID 21371785 DOI: 10.1016/J.Neurobiolaging.2011.01.006  0.424
2012 Head E, Davis R, Caban-Holt A, Dennis B, Jicha G, Powell D, Abner E, Dowling AL, Gold B, Wyss-Coray T, Schmitt F. P2-267: A longitudinal study of aging and the development of Alzheimer's disease in people with Down syndrome Alzheimer's & Dementia. 8: P355-P356. DOI: 10.1016/J.Jalz.2012.05.975  0.344
2012 Czirr E, Jaeger P, Wyss-Coray T. S1-02-04: Plasma proteomics as a discovery tool for novel pathways in neurodegenerative diseases Alzheimer's & Dementia. 8: P79-P80. DOI: 10.1016/J.Jalz.2012.05.189  0.778
2011 Wang Q, Rozelle AL, Lepus CM, Scanzello CR, Song JJ, Larsen DM, Crish JF, Bebek G, Ritter SY, Lindstrom TM, Hwang I, Wong HH, Punzi L, Encarnacion A, Shamloo M, ... ... Wyss-Coray T, et al. Identification of a central role for complement in osteoarthritis. Nature Medicine. 17: 1674-9. PMID 22057346 DOI: 10.1038/Nm.2543  0.312
2011 Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A, Lucin KM, Czirr E, Park JS, Couillard-Després S, Aigner L, ... ... Wyss-Coray T, et al. The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature. 477: 90-4. PMID 21886162 DOI: 10.1038/Nature10357  0.795
2011 Britschgi M, Rufibach K, Huang SL, Clark CM, Kaye JA, Li G, Peskind ER, Quinn JF, Galasko DR, Wyss-Coray T. Modeling of pathological traits in Alzheimer's disease based on systemic extracellular signaling proteome. Molecular & Cellular Proteomics : McP. 10: M111.008862. PMID 21742799 DOI: 10.1074/Mcp.M111.008862  0.71
2011 Moriyama M, Fukuhara T, Britschgi M, He Y, Narasimhan R, Villeda S, Molina H, Huber BT, Holers M, Wyss-Coray T. Complement receptor 2 is expressed in neural progenitor cells and regulates adult hippocampal neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 3981-9. PMID 21411641 DOI: 10.1523/Jneurosci.3617-10.2011  0.782
2011 Tansey MG, Wyss-Coray T. Workshop summary: roles of the TNF family in neuronal development, function and pathology. Advances in Experimental Medicine and Biology. 691: 537-8. PMID 21153358 DOI: 10.1007/978-1-4419-6612-4_55  0.384
2010 Jaeger PA, Wyss-Coray T. Beclin 1 complex in autophagy and Alzheimer disease. Archives of Neurology. 67: 1181-4. PMID 20937944 DOI: 10.1001/archneurol.2010.258  0.761
2010 Lanz TV, Ding Z, Ho PP, Luo J, Agrawal AN, Srinagesh H, Axtell R, Zhang H, Platten M, Wyss-Coray T, Steinman L. Angiotensin II sustains brain inflammation in mice via TGF-beta. The Journal of Clinical Investigation. 120: 2782-94. PMID 20628203 DOI: 10.1172/Jci41709  0.345
2010 Buttini M, Masliah E, Yu GQ, Palop JJ, Chang S, Bernardo A, Lin C, Wyss-Coray T, Huang Y, Mucke L. Cellular source of apolipoprotein E4 determines neuronal susceptibility to excitotoxic injury in transgenic mice. The American Journal of Pathology. 177: 563-9. PMID 20595630 DOI: 10.2353/Ajpath.2010.090973  0.76
2010 Jaeger PA, Pickford F, Sun CH, Lucin KM, Masliah E, Wyss-Coray T. Regulation of amyloid precursor protein processing by the Beclin 1 complex. Plos One. 5: e11102. PMID 20559548 DOI: 10.1371/Journal.Pone.0011102  0.768
2010 Fenili D, Wyss-Coray T, McLaurin J, Jaeger PA. Keystone symposium on Alzheimer's disease: Beyond amyloid Future Neurology. 5: 353-355. DOI: 10.2217/fnl.10.16  0.767
2010 Schäfer KH, Letiembre M, Semar S, Klotz M, Liu A, Fassbender K, Wyss-Coray T, Schulz-Schaeffer W, Ginneken CV. Potential early diagnosis of Alzheimers disease using changes of the enteric nervous system Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1736  0.315
2009 Lucin KM, Wyss-Coray T. Immune activation in brain aging and neurodegeneration: too much or too little? Neuron. 64: 110-22. PMID 19840553 DOI: 10.1016/j.neuron.2009.08.039  0.373
2009 Knowles JK, Rajadas J, Nguyen TV, Yang T, LeMieux MC, Vander Griend L, Ishikawa C, Massa SM, Wyss-Coray T, Longo FM. The p75 neurotrophin receptor promotes amyloid-beta(1-42)-induced neuritic dystrophy in vitro and in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 10627-37. PMID 19710315 DOI: 10.1523/Jneurosci.0620-09.2009  0.379
2009 Luo J, Wyss-Coray T. Bioluminescence analysis of Smad-dependent TGF-beta signaling in live mice. Methods in Molecular Biology (Clifton, N.J.). 574: 193-202. PMID 19685310 DOI: 10.1007/978-1-60327-321-3_16  0.355
2009 Britschgi M, Olin CE, Johns HT, Takeda-Uchimura Y, LeMieux MC, Rufibach K, Rajadas J, Zhang H, Tomooka B, Robinson WH, Clark CM, Fagan AM, Galasko DR, Holtzman DM, Jutel M, ... ... Wyss-Coray T, et al. Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 106: 12145-50. PMID 19581601 DOI: 10.1073/Pnas.0904866106  0.716
2009 Tesseur I, Zhang H, Brecht W, Corn J, Gong JS, Yanagisawa K, Michikawa M, Weisgraber K, Huang Y, Wyss-Coray T. Bioactive TGF-beta can associate with lipoproteins and is enriched in those containing apolipoprotein E3. Journal of Neurochemistry. 110: 1254-62. PMID 19549280 DOI: 10.1111/J.1471-4159.2009.06222.X  0.696
2009 Jaeger PA, Wyss-Coray T. All-you-can-eat: autophagy in neurodegeneration and neuroprotection. Molecular Neurodegeneration. 4: 16. PMID 19348680 DOI: 10.1186/1750-1326-4-16  0.751
2009 Cheng JS, Dubal DB, Kim DH, Legleiter J, Cheng IH, Yu GQ, Tesseur I, Wyss-Coray T, Bonaldo P, Mucke L. Collagen VI protects neurons against Abeta toxicity. Nature Neuroscience. 12: 119-21. PMID 19122666 DOI: 10.1038/Nn.2240  0.799
2009 Britschgi M, Wyss-Coray T. Blood protein signature for the early diagnosis of Alzheimer disease. Archives of Neurology. 66: 161-5. PMID 19064741 DOI: 10.1001/Archneurol.2008.530  0.681
2008 Villeda S, Wyss-Coray T. Microglia--a wrench in the running wheel? Neuron. 59: 527-9. PMID 18760689 DOI: 10.1016/J.Neuron.2008.08.005  0.713
2008 Tamgüney G, Giles K, Glidden DV, Lessard P, Wille H, Tremblay P, Groth DF, Yehiely F, Korth C, Moore RC, Tatzelt J, Rubinstein E, Boucheix C, Yang X, Stanley P, ... ... Wyss-Coray T, et al. Genes contributing to prion pathogenesis. The Journal of General Virology. 89: 1777-88. PMID 18559949 DOI: 10.1099/Vir.0.2008/001255-0  0.756
2008 Pickford F, Masliah E, Britschgi M, Lucin K, Narasimhan R, Jaeger PA, Small S, Spencer B, Rockenstein E, Levine B, Wyss-Coray T. The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. The Journal of Clinical Investigation. 118: 2190-9. PMID 18497889 DOI: 10.1172/Jci33585  0.828
2008 Luo J, Ho P, Steinman L, Wyss-Coray T. Bioluminescence in vivo imaging of autoimmune encephalomyelitis predicts disease. Journal of Neuroinflammation. 5: 6. PMID 18237444 DOI: 10.1186/1742-2094-5-6  0.36
2008 Cheng JS, Cheng IH, Kim DH, Wu T, Tesseur I, Wyss-Coray T, Bonaldo P, Scearce-Levie K, Mucke L. P1-413: Collagen VI protects neurons against amyloid-beta toxicity Alzheimer's & Dementia. 4: T340-T340. DOI: 10.1016/J.Jalz.2008.05.995  0.788
2008 Wyss-Coray T. ‘S1-03-04: The autophagy protein Beclin 1 is reduced in early Alzheimer's disease and regulates Abeta accumulation in vivo Alzheimer's & Dementia. 4: T104-T104. DOI: 10.1016/j.jalz.2008.05.200  0.475
2008 Britschgi M, Olin CE, Johns H, Takeda-Uchimura Y, Rufibach K, Tomooka B, Robinson WH, Rajadas J, Clark CM, Fagan AM, Galasko DG, Holtzman DM, Jutel M, Leszek J, Li G, ... ... Wyss-Coray T, et al. P2-294: Microarray profiling reveals autoantibody reactivities against abnormal amyloid peptide conformations decline with age and in Alzheimer's disease Alzheimer's & Dementia. 4: T458-T459. DOI: 10.1016/J.Jalz.2008.05.1370  0.725
2007 Luo J, Ho PP, Buckwalter MS, Hsu T, Lee LY, Zhang H, Kim DK, Kim SJ, Gambhir SS, Steinman L, Wyss-Coray T. Glia-dependent TGF-beta signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis. The Journal of Clinical Investigation. 117: 3306-15. PMID 17965773 DOI: 10.1172/Jci31763  0.677
2007 Ray S, Britschgi M, Herbert C, Takeda-Uchimura Y, Boxer A, Blennow K, Friedman LF, Galasko DR, Jutel M, Karydas A, Kaye JA, Leszek J, Miller BL, Minthon L, Quinn JF, ... ... Wyss-Coray T, et al. Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins. Nature Medicine. 13: 1359-62. PMID 17934472 DOI: 10.1038/Nm1653  0.701
2007 Britschgi M, Wyss-Coray T. Systemic and acquired immune responses in Alzheimer's disease. International Review of Neurobiology. 82: 205-33. PMID 17678963 DOI: 10.1016/S0074-7742(07)82011-3  0.682
2007 Satterwhite TS, Chong AK, Luo J, Pham H, Costa M, Longaker MT, Wyss-Coray T, Chang J. In vitro analysis of transforming growth factor-beta1 inhibition in novel transgenic SBE-luciferase mice. Annals of Plastic Surgery. 59: 207-13. PMID 17667417 DOI: 10.1097/01.Sap.0000252732.25168.34  0.311
2007 Ando T, Hatsushika K, Wako M, Ohba T, Koyama K, Ohnuma Y, Katoh R, Ogawa H, Okumura K, Luo J, Wyss-Coray T, Nakao A. Orally administered TGF-beta is biologically active in the intestinal mucosa and enhances oral tolerance. The Journal of Allergy and Clinical Immunology. 120: 916-23. PMID 17606291 DOI: 10.1016/J.Jaci.2007.05.023  0.317
2007 Britschgi M, Wyss-Coray T. Immune cells may fend off Alzheimer disease. Nature Medicine. 13: 408-9. PMID 17415372 DOI: 10.1038/Nm0407-408  0.697
2007 Ray S, Wyss-Coray T, Britschgi M. S2-02-04: Plasma protein biomarkers to predict early Alzheimer's disease Alzheimer's & Dementia. 3: S181-S181. DOI: 10.1016/J.Jalz.2007.04.056  0.665
2006 Tesseur I, Wyss-Coray T. A role for TGF-beta signaling in neurodegeneration: evidence from genetically engineered models. Current Alzheimer Research. 3: 505-13. PMID 17168649 DOI: 10.2174/156720506779025297  0.743
2006 Luo J, Lin AH, Masliah E, Wyss-Coray T. Bioluminescence imaging of Smad signaling in living mice shows correlation with excitotoxic neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 103: 18326-31. PMID 17110447 DOI: 10.1073/Pnas.0605077103  0.397
2006 Tesseur I, Zou K, Esposito L, Bard F, Berber E, Can JV, Lin AH, Crews L, Tremblay P, Mathews P, Mucke L, Masliah E, Wyss-Coray T. Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology. The Journal of Clinical Investigation. 116: 3060-9. PMID 17080199 DOI: 10.1172/Jci27341  0.79
2006 Buckwalter MS, Coleman BS, Buttini M, Barbour R, Schenk D, Games D, Seubert P, Wyss-Coray T. Increased T cell recruitment to the CNS after amyloid beta 1-42 immunization in Alzheimer's mice overproducing transforming growth factor-beta 1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11437-41. PMID 17079673 DOI: 10.1523/JNEUROSCI.2436-06.2006  0.706
2006 Dhib-Jalbut S, Arnold DL, Cleveland DW, Fisher M, Friedlander RM, Mouradian MM, Przedborski S, Trapp BD, Wyss-Coray T, Yong VW. Neurodegeneration and neuroprotection in multiple sclerosis and other neurodegenerative diseases. Journal of Neuroimmunology. 176: 198-215. PMID 16983747 DOI: 10.1016/J.Jneuroim.2006.03.027  0.372
2006 Wyss-Coray T. Inflammation in Alzheimer disease: driving force, bystander or beneficial response? Nature Medicine. 12: 1005-15. PMID 16960575 DOI: 10.1038/nm1484  0.381
2006 Wyss-Coray T. Tgf-Beta pathway as a potential target in neurodegeneration and Alzheimer's. Current Alzheimer Research. 3: 191-5. PMID 16842094 DOI: 10.2174/156720506777632916  0.416
2006 Buckwalter MS, Yamane M, Coleman BS, Ormerod BK, Chin JT, Palmer T, Wyss-Coray T. Chronically increased transforming growth factor-beta1 strongly inhibits hippocampal neurogenesis in aged mice. The American Journal of Pathology. 169: 154-64. PMID 16816369 DOI: 10.2353/ajpath.2006.051272  0.699
2006 Tesseur I, Zou K, Berber E, Zhang H, Wyss-Coray T. Highly sensitive and specific bioassay for measuring bioactive TGF-beta. Bmc Cell Biology. 7: 15. PMID 16549026 DOI: 10.1186/1471-2121-7-15  0.68
2006 Pickford F, Masliah E, Small S, Rockenstein E, Levine B, Wyss-Coray T. O4-05-02: Deficiency of the Beclin 1 autophagy protein promotes Alzheimer's disease pathology Alzheimer's & Dementia. 2: S85-S85. DOI: 10.1016/J.Jalz.2006.05.328  0.461
2005 Zhang H, Zou K, Tesseur I, Wyss-Coray T. Small molecule tgf-beta mimetics as potential neuroprotective factors. Current Alzheimer Research. 2: 183-6. PMID 15974916 DOI: 10.2174/1567205053585756  0.721
2005 Lin AH, Luo J, Mondshein LH, ten Dijke P, Vivien D, Contag CH, Wyss-Coray T. Global analysis of Smad2/3-dependent TGF-beta signaling in living mice reveals prominent tissue-specific responses to injury. Journal of Immunology (Baltimore, Md. : 1950). 175: 547-54. PMID 15972691 DOI: 10.4049/Jimmunol.175.1.547  0.388
2005 Gaertner RF, Wyss-Coray T, Von Euw D, Lesné S, Vivien D, Lacombe P. Reduced brain tissue perfusion in TGF-beta 1 transgenic mice showing Alzheimer's disease-like cerebrovascular abnormalities. Neurobiology of Disease. 19: 38-46. PMID 15837559 DOI: 10.1016/J.Nbd.2004.11.008  0.367
2004 Crews L, Wyss-Coray T, Masliah E. Insights into the pathogenesis of hydrocephalus from transgenic and experimental animal models. Brain Pathology (Zurich, Switzerland). 14: 312-6. PMID 15446587 DOI: 10.1111/J.1750-3639.2004.Tb00070.X  0.371
2004 Wyss-Coray T. Transforming growth factor-beta signaling pathway as a therapeutic target in neurodegeneration. Journal of Molecular Neuroscience : Mn. 24: 149-53. PMID 15314264 DOI: 10.1385/JMN:24:1:149  0.414
2004 Buckwalter MS, Wyss-Coray T. Modelling neuroinflammatory phenotypes in vivo. Journal of Neuroinflammation. 1: 10. PMID 15285805 DOI: 10.1186/1742-2094-1-10  0.697
2004 Brecht WJ, Harris FM, Chang S, Tesseur I, Yu GQ, Xu Q, Dee Fish J, Wyss-Coray T, Buttini M, Mucke L, Mahley RW, Huang Y. Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2527-34. PMID 15014128 DOI: 10.1523/Jneurosci.4315-03.2004  0.791
2004 Harris FM, Tesseur I, Brecht WJ, Xu Q, Mullendorff K, Chang S, Wyss-Coray T, Mahley RW, Huang Y. Astroglial regulation of apolipoprotein E expression in neuronal cells. Implications for Alzheimer's disease. The Journal of Biological Chemistry. 279: 3862-8. PMID 14585838 DOI: 10.1074/Jbc.M309475200  0.706
2004 Brecht WJ, Harris FM, Chang S, Tesseur I, Yu G, Fish JD, Wyss-Coray T, Buttini M, Mucke L, Mahley RW, Huang Y. P2-292 Neuron-specific apoE4 proteolysis is associated with increased tau phosphorylation in the brains of transgenic mice Neurobiology of Aging. 25: S316. DOI: 10.1016/S0197-4580(04)81037-6  0.769
2004 Buckwalter MS, Yamane M, Lee S, Palmer TD, Wyss-Coray T. P1-253 Chronically increased brain TGF beta-1 leads to hippocampal microgliosis and decreased hippocampal neurogenesis in adult mice Neurobiology of Aging. 25: S168. DOI: 10.1016/S0197-4580(04)80566-9  0.681
2004 Tesseur IC, Zou K, Masliah E, Corn J, Brionne T, Bard F, Wyss-Coray T. P1-203 Inhibition of the TGF-beta signaling pathway results in increased neurodegeneration and amyloid deposition in human APP transgenic mice Neurobiology of Aging. 25: S154. DOI: 10.1016/S0197-4580(04)80516-5  0.376
2003 Brionne TC, Tesseur I, Masliah E, Wyss-Coray T. Loss of TGF-beta 1 leads to increased neuronal cell death and microgliosis in mouse brain. Neuron. 40: 1133-45. PMID 14687548 DOI: 10.1016/S0896-6273(03)00766-9  0.797
2003 Harris FM, Brecht WJ, Xu Q, Tesseur I, Kekonius L, Wyss-Coray T, Fish JD, Masliah E, Hopkins PC, Scearce-Levie K, Weisgraber KH, Mucke L, Mahley RW, Huang Y. Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 10966-71. PMID 12939405 DOI: 10.1073/Pnas.1434398100  0.824
2003 Wyss-Coray T, Loike JD, Brionne TC, Lu E, Anankov R, Yan F, Silverstein SC, Husemann J. Adult mouse astrocytes degrade amyloid-beta in vitro and in situ. Nature Medicine. 9: 453-7. PMID 12612547 DOI: 10.1038/Nm838  0.801
2002 Buckwalter M, Pepper JP, Gaertner RF, Von Euw D, Lacombe P, Wyss-Coray T. Molecular and functional dissection of TGF-beta1-induced cerebrovascular abnormalities in transgenic mice. Annals of the New York Academy of Sciences. 977: 87-95. PMID 12480736 DOI: 10.1111/j.1749-6632.2002.tb04801.x  0.681
2002 Wyss-Coray T, Mucke L. Inflammation in neurodegenerative disease--a double-edged sword. Neuron. 35: 419-32. PMID 12165466 DOI: 10.1016/S0896-6273(02)00794-8  0.578
2002 Wyss-Coray T, Yan F, Lin AH, Lambris JD, Alexander JJ, Quigg RJ, Masliah E. Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 10837-42. PMID 12119423 DOI: 10.1073/Pnas.162350199  0.481
2001 Wyss-Coray T, McConlogue L, Kindy M, Schmidt AM, Du Yan S, Stern DM. Key signaling pathways regulate the biological activities and accumulation of amyloid-beta. Neurobiology of Aging. 22: 967-73. PMID 11755005 DOI: 10.1016/S0197-4580(01)00305-0  0.328
2001 Masliah E, Ho G, Wyss-Coray T. Functional role of TGF beta in Alzheimer's disease microvascular injury: lessons from transgenic mice. Neurochemistry International. 39: 393-400. PMID 11578774 DOI: 10.1016/S0197-0186(01)00046-8  0.415
2001 Huang Y, Liu XQ, Wyss-Coray T, Brecht WJ, Sanan DA, Mahley RW. Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons. Proceedings of the National Academy of Sciences of the United States of America. 98: 8838-43. PMID 11447277 DOI: 10.1073/Pnas.151254698  0.417
2001 Wyss-Coray T, Lin C, Yan F, Yu GQ, Rohde M, McConlogue L, Masliah E, Mucke L. TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice. Nature Medicine. 7: 612-8. PMID 11329064 DOI: 10.1038/87945  0.614
2000 Wyss-Coray T, Mucke L. Ibuprofen, inflammation and Alzheimer disease. Nature Medicine. 6: 973-4. PMID 10973311 DOI: 10.1038/79661  0.571
2000 Akiyama H, Barger S, Barnum S, Bradt B, Bauer J, Cole GM, Cooper NR, Eikelenboom P, Emmerling M, Fiebich BL, Finch CE, Frautschy S, Griffin WS, Hampel H, Hull M, ... ... Wyss-Coray T, et al. Inflammation and Alzheimer's disease. Neurobiology of Aging. 21: 383-421. PMID 10858586 DOI: 10.1016/S0197-4580(00)00124-X  0.563
2000 Wyss-Coray T, Lin C, von Euw D, Masliah E, Mucke L, Lacombe P. Alzheimer's disease-like cerebrovascular pathology in transforming growth factor-beta 1 transgenic mice and functional metabolic correlates. Annals of the New York Academy of Sciences. 903: 317-23. PMID 10818521 DOI: 10.1111/J.1749-6632.2000.Tb06382.X  0.639
2000 Buttini M, Akeefe H, Lin C, Mahley RW, Pitas RE, Wyss-Coray T, Mucke L. Dominant negative effects of apolipoprotein E4 revealed in transgenic models of neurodegenerative disease. Neuroscience. 97: 207-10. PMID 10799751 DOI: 10.1016/S0306-4522(00)00069-5  0.553
2000 Wyss-Coray T, Lin C, Sanan DA, Mucke L, Masliah E. Chronic overproduction of transforming growth factor-beta1 by astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic mice. The American Journal of Pathology. 156: 139-50. PMID 10623661 DOI: 10.1016/S0002-9440(10)64713-X  0.624
2000 Wyss-Coray T, Barcellos L, Oksenberg J, Green A, Masliah E, Mucke L. Transforming growth factor (TGF)-β1 modifies Alzheimer's-type pathology in a transgenic mice and humans Neurobiology of Aging. 21: 125. DOI: 10.1016/S0197-4580(00)82362-3  0.576
1999 Huang F, Buttini M, Wyss-Coray T, McConlogue L, Kodama T, Pitas RE, Mucke L. Elimination of the class A scavenger receptor does not affect amyloid plaque formation or neurodegeneration in transgenic mice expressing human amyloid protein precursors. The American Journal of Pathology. 155: 1741-7. PMID 10550330 DOI: 10.1016/S0002-9440(10)65489-2  0.633
1999 Xu X, Yang D, Wyss-Coray T, Yan J, Gan L, Sun Y, Mucke L. Wild-type but not Alzheimer-mutant amyloid precursor protein confers resistance against p53-mediated apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 96: 7547-52. PMID 10377452 DOI: 10.1073/pnas.96.13.7547  0.697
1999 Buttini M, Orth M, Bellosta S, Akeefe H, Pitas RE, Wyss-Coray T, Mucke L, Mahley RW. Expression of human apolipoprotein E3 or E4 in the brains of Apoe-/- mice: isoform-specific effects on neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4867-80. PMID 10366621 DOI: 10.1523/Jneurosci.19-12-04867.1999  0.633
1998 Marshall DC, Wyss-Coray T, Abraham CR. Induction of matrix metalloproteinase-2 in human immunodeficiency virus-1 glycoprotein 120 transgenic mouse brains. Neuroscience Letters. 254: 97-100. PMID 9779929 DOI: 10.1016/S0304-3940(98)00674-0  0.309
1998 Buttini M, Westland CE, Masliah E, Yafeh AM, Wyss-Coray T, Mucke L. Novel role of human CD4 molecule identified in neurodegeneration. Nature Medicine. 4: 441-6. PMID 9546790 DOI: 10.1038/Nm0498-441  0.602
1997 Wyss-Coray T, Masliah E, Mallory M, McConlogue L, Johnson-Wood K, Lin C, Mucke L. Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease. Nature. 389: 603-6. PMID 9335500 DOI: 10.1038/39321  0.62
1997 Wyss-Coray T, Borrow P, Brooker MJ, Mucke L. Astroglial overproduction of TGF-beta 1 enhances inflammatory central nervous system disease in transgenic mice . Journal of Neuroimmunology. 77: 45-50. PMID 9209267 DOI: 10.1016/S0165-5728(97)00049-0  0.596
1997 Mattson MP, Barger SW, Furukawa K, Bruce AJ, Wyss-Coray T, Mark RJ, Mucke L. Cellular signaling roles of TGF beta, TNF alpha and beta APP in brain injury responses and Alzheimer's disease. Brain Research. Brain Research Reviews. 23: 47-61. PMID 9063586 DOI: 10.1016/S0165-0173(96)00014-8  0.593
1996 Wyss-Coray T, Masliah E, Toggas SM, Rockenstein EM, Brooker MJ, Lee HS, Mucke L. Dysregulation of signal transduction pathways as a potential mechanism of nervous system alterations in HIV-1 gp120 transgenic mice and humans with HIV-1 encephalitis. The Journal of Clinical Investigation. 97: 789-98. PMID 8609236 DOI: 10.1172/Jci118478  0.558
1995 Wyss-Coray T, Feng L, Masliah E, Ruppe MD, Lee HS, Toggas SM, Rockenstein EM, Mucke L. Increased central nervous system production of extracellular matrix components and development of hydrocephalus in transgenic mice overexpressing transforming growth factor-beta 1. The American Journal of Pathology. 147: 53-67. PMID 7604885  0.555
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