John K. Belknap, Ph.D. - Publications

Affiliations: 
Behavioral Neuroscience Oregon Health and Science University, Portland, OR 
Area:
Genetics, Alcohol and Drug Abuse, Statistics, Microarray Analysis, QTL Analysis Mouse Models
Website:
http://www.ohsu.edu/xd/education/schools/school-of-medicine/academic-programs/graduate-studies/faculty/grad-studies-faculty.cfm?facultyid=33

131 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Iancu OD, Boutros SW, Olsen RHJ, Davis MJ, Stewart B, Eiwaz M, Marzulla T, Belknap J, Fallgren CM, Edmondson EF, Weil MM, Raber J. Space Radiation Alters Genotype-Phenotype Correlations in Fear Learning and Memory Tests. Frontiers in Genetics. 9: 404. PMID 30356920 DOI: 10.3389/Fgene.2018.00404  0.327
2016 Shi X, Walter NA, Harkness JH, Neve KA, Williams RW, Lu L, Belknap JK, Eshleman AJ, Phillips TJ, Janowsky A. Genetic Polymorphisms Affect Mouse and Human Trace Amine-Associated Receptor 1 Function. Plos One. 11: e0152581. PMID 27031617 DOI: 10.1371/Journal.Pone.0152581  0.388
2014 Metten P, Iancu OD, Spence SE, Walter NA, Oberbeck D, Harrington CA, Colville A, McWeeney S, Phillips TJ, Buck KJ, Crabbe JC, Belknap JK, Hitzemann RJ. Dual-trait selection for ethanol consumption and withdrawal: genetic and transcriptional network effects. Alcoholism, Clinical and Experimental Research. 38: 2915-24. PMID 25581648 DOI: 10.1111/Acer.12574  0.486
2014 Hitzemann R, Bottomly D, Iancu O, Buck K, Wilmot B, Mooney M, Searles R, Zheng C, Belknap J, Crabbe J, McWeeney S. The genetics of gene expression in complex mouse crosses as a tool to study the molecular underpinnings of behavior traits. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 25: 12-22. PMID 24374554 DOI: 10.1007/S00335-013-9495-6  0.348
2014 Crabbe JC, Metten P, Belknap JK, Spence SE, Cameron AJ, Schlumbohm JP, Huang LC, Barkley-Levenson AM, Ford MM, Phillips TJ. Progress in a replicated selection for elevated blood ethanol concentrations in HDID mice. Genes, Brain, and Behavior. 13: 236-46. PMID 24219304 DOI: 10.1111/Gbb.12105  0.432
2013 Belknap JK, McWeeney S, Reed C, Burkhart-Kasch S, McKinnon CS, Li N, Baba H, Scibelli AC, Hitzemann R, Phillips TJ. Genetic factors involved in risk for methamphetamine intake and sensitization. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 24: 446-58. PMID 24217691 DOI: 10.1007/S00335-013-9484-9  0.486
2013 Olsen RH, Allen CN, Derkach VA, Phillips TJ, Belknap JK, Raber J. Impaired memory and reduced sensitivity to the circadian period lengthening effects of methamphetamine in mice selected for high methamphetamine consumption. Behavioural Brain Research. 256: 197-204. PMID 23954232 DOI: 10.1016/J.Bbr.2013.08.015  0.371
2012 Mukherjee A, Larson EA, Carlos AS, Belknap JK, Rotwein P, Klein RF. Congenic mice provide in vivo evidence for a genetic locus that modulates intrinsic transforming growth factor β1-mediated signaling and bone acquisition. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 1345-56. PMID 22407846 DOI: 10.1002/jbmr.1590  0.417
2012 Blednov YA, Mayfield RD, Belknap J, Harris RA. Behavioral actions of alcohol: phenotypic relations from multivariate analysis of mutant mouse data. Genes, Brain, and Behavior. 11: 424-35. PMID 22405477 DOI: 10.1111/J.1601-183X.2012.00780.X  0.396
2011 Laderas TG, Walter NA, Mooney M, Vartanian K, Darakjian P, Buck K, Harrington CA, Belknap J, Hitzemann R, McWeeney SK. Computational detection of alternative exon usage. Frontiers in Neuroscience. 5: 69. PMID 21625610 DOI: 10.3389/Fnins.2011.00069  0.341
2011 Fei SS, Wilmarth PA, Hitzemann RJ, McWeeney SK, Belknap JK, David LL. Protein database and quantitative analysis considerations when integrating genetics and proteomics to compare mouse strains. Journal of Proteome Research. 10: 2905-12. PMID 21553863 DOI: 10.1021/Pr200133P  0.398
2011 Nair HK, Hain H, Quock RM, Philip VM, Chesler EJ, Belknap JK, Lariviere WR. Genomic loci and candidate genes underlying inflammatory nociception. Pain. 152: 599-606. PMID 21195549 DOI: 10.1016/J.Pain.2010.11.029  0.448
2010 Iancu OD, Darakjian P, Walter NA, Malmanger B, Oberbeck D, Belknap J, McWeeney S, Hitzemann R. Genetic diversity and striatal gene networks: focus on the heterogeneous stock-collaborative cross (HS-CC) mouse. Bmc Genomics. 11: 585. PMID 20959017 DOI: 10.1186/1471-2164-11-585  0.414
2010 Crabbe JC, Phillips TJ, Belknap JK. The complexity of alcohol drinking: studies in rodent genetic models. Behavior Genetics. 40: 737-50. PMID 20552264 DOI: 10.1007/s10519-010-9371-z  0.399
2010 Phillips TJ, Reed C, Burkhart-Kasch S, Li N, Hitzemann R, Yu CH, Brown LL, Helms ML, Crabbe JC, Belknap JK. A method for mapping intralocus interactions influencing excessive alcohol drinking. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 21: 39-51. PMID 20033183 DOI: 10.1007/S00335-009-9239-9  0.41
2010 Blednov YA, Ozburn AR, Walker D, Ahmed S, Belknap JK, Harris RA. Hybrid mice as genetic models of high alcohol consumption. Behavior Genetics. 40: 93-110. PMID 19798565 DOI: 10.1007/S10519-009-9298-4  0.444
2009 Hitzemann R, Edmunds S, Wu W, Malmanger B, Walter N, Belknap J, Darakjian P, McWeeney S. Detection of reciprocal quantitative trait loci for acute ethanol withdrawal and ethanol consumption in heterogeneous stock mice. Psychopharmacology. 203: 713-22. PMID 19052728 DOI: 10.1007/S00213-008-1418-Y  0.363
2009 Kamens HM, McKinnon CS, Li N, Helms ML, Belknap JK, Phillips TJ. The alpha 3 subunit gene of the nicotinic acetylcholine receptor is a candidate gene for ethanol stimulation. Genes, Brain, and Behavior. 8: 600-9. PMID 18826434 DOI: 10.1111/j.1601-183X.2008.00444.x  0.44
2009 Metten P, Crabbe JC, Belknap JK. Genetic correlates of morphine withdrawal in 14 inbred mouse strains. Drug and Alcohol Dependence. 99: 123-31. PMID 18774238 DOI: 10.1016/J.Drugalcdep.2008.07.006  0.414
2009 Kamens HM, McKinnon CS, Li N, Helms ML, Belknap JK, Phillips TJ. Erratum: Thαe 3 subunit gene of the nicotinic acetylcholine receptor is a candidate gene for ethanol stimulation (Genes, Brain and Behavior (2008) (DOI: 10.1111/j.1601-183X.2008.00444.x)) Genes, Brain and Behavior. 8. DOI: 10.1111/J.1601-183X.2009.00508.X  0.311
2008 Belknap JK, Metten P, Beckley EH, Crabbe JC. Multivariate analyses reveal common and drug-specific genetic influences on responses to four drugs of abuse. Trends in Pharmacological Sciences. 29: 537-43. PMID 18774184 DOI: 10.1016/J.Tips.2008.07.010  0.416
2008 Hitzemann R, Malmanger B, Belknap J, Darakjian P, McWeeney S. Short-term selective breeding for high and low prepulse inhibition of the acoustic startle response; pharmacological characterization and QTL mapping in the selected lines. Pharmacology, Biochemistry, and Behavior. 90: 525-33. PMID 18513787 DOI: 10.1016/J.Pbb.2008.04.004  0.439
2008 Hofstetter JR, Hitzemann RJ, Belknap JK, Walter NA, McWeeney SK, Mayeda AR. Characterization of the quantitative trait locus for haloperidol-induced catalepsy on distal mouse chromosome 1. Genes, Brain, and Behavior. 7: 214-23. PMID 17696997 DOI: 10.1111/J.1601-183X.2007.00340.X  0.432
2007 Walter NA, McWeeney SK, Peters ST, Belknap JK, Hitzemann R, Buck KJ. SNPs matter: impact on detection of differential expression. Nature Methods. 4: 679-80. PMID 17762873 DOI: 10.1038/Nmeth0907-679  0.335
2006 Malmanger B, Lawler M, Coulombe S, Murray R, Cooper S, Polyakov Y, Belknap J, Hitzemann R. Further studies on using multiple-cross mapping (MCM) to map quantitative trait loci. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 17: 1193-204. PMID 17143586 DOI: 10.1007/S00335-006-0070-2  0.409
2006 Saba L, Bhave SV, Grahame N, Bice P, Lapadat R, Belknap J, Hoffman PL, Tabakoff B. Candidate genes and their regulatory elements: alcohol preference and tolerance. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 17: 669-88. PMID 16783646 DOI: 10.1007/S00335-005-0190-0  0.367
2006 Peirce JL, Li H, Wang J, Manly KF, Hitzemann RJ, Belknap JK, Rosen GD, Goodwin S, Sutter TR, Williams RW, Lu L. How replicable are mRNA expression QTL? Mammalian Genome : Official Journal of the International Mammalian Genome Society. 17: 643-56. PMID 16783644 DOI: 10.1007/S00335-005-0187-8  0.372
2006 Mulligan MK, Ponomarev I, Hitzemann RJ, Belknap JK, Tabakoff B, Harris RA, Crabbe JC, Blednov YA, Grahame NJ, Phillips TJ, Finn DA, Hoffman PL, Iyer VR, Koob GF, Bergeson SE. Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. Proceedings of the National Academy of Sciences of the United States of America. 103: 6368-73. PMID 16618939 DOI: 10.1073/Pnas.0510188103  0.383
2006 Sikela JM, Maclaren EJ, Kim Y, Karimpour-Fard A, Cai WW, Pollack J, Hitzemann R, Belknap J, McWeeney S, Kerns RT, Downing C, Johnson TE, Grant KJ, Tabakoff B, Hoffman P, et al. DNA microarray and proteomic strategies for understanding alcohol action. Alcoholism, Clinical and Experimental Research. 30: 700-8. PMID 16573589 DOI: 10.1111/J.1530-0277.2006.00081.X  0.416
2006 Bice PJ, Foroud T, Carr LG, Zhang L, Liu L, Grahame NJ, Lumeng L, Li TK, Belknap JK. Identification of QTLs influencing alcohol preference in the High Alcohol Preferring (HAP) and Low Alcohol Preferring (LAP) mouse lines. Behavior Genetics. 36: 248-60. PMID 16482403 DOI: 10.1007/S10519-005-9019-6  0.431
2005 Matthews DB, Bhave SV, Belknap JK, Brittingham C, Chesler EJ, Hitzemann RJ, Hoffmann PL, Lu L, McWeeney S, Miles MF, Tabakoff B, Williams RW. Complex genetics of interactions of alcohol and CNS function and behavior. Alcoholism, Clinical and Experimental Research. 29: 1706-19. PMID 16205371 DOI: 10.1097/01.Alc.0000179209.44407.Df  0.412
2005 Palmer AA, Verbitsky M, Suresh R, Kamens HM, Reed CL, Li N, Burkhart-Kasch S, McKinnon CS, Belknap JK, Gilliam TC, Phillips TJ. Gene expression differences in mice divergently selected for methamphetamine sensitivity. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 16: 291-305. PMID 16104378 DOI: 10.1007/S00335-004-2451-8  0.434
2005 Fehr C, Shirley RL, Crabbe JC, Belknap JK, Buck KJ, Phillips TJ. The syntaxin binding protein 1 gene (Stxbp1) is a candidate for an ethanol preference drinking locus on mouse chromosome 2. Alcoholism, Clinical and Experimental Research. 29: 708-20. PMID 15897714 DOI: 10.1097/01.Alc.0000164366.18376.Ef  0.429
2005 Finn DA, Belknap JK, Cronise K, Yoneyama N, Murillo A, Crabbe JC. A procedure to produce high alcohol intake in mice. Psychopharmacology. 178: 471-80. PMID 15765261 DOI: 10.1007/S00213-004-2039-8  0.391
2005 Rhodes JS, Best K, Belknap JK, Finn DA, Crabbe JC. Evaluation of a simple model of ethanol drinking to intoxication in C57BL/6J mice. Physiology & Behavior. 84: 53-63. PMID 15642607 DOI: 10.1016/J.Physbeh.2004.10.007  0.385
2004 Hitzemann R, Reed C, Malmanger B, Lawler M, Hitzemann B, Cunningham B, McWeeney S, Belknap J, Harrington C, Buck K, Phillips T, Crabbe J. On the integration of alcohol-related quantitative trait loci and gene expression analyses. Alcoholism, Clinical and Experimental Research. 28: 1437-48. PMID 15597075 DOI: 10.1097/01.Alc.0000139827.86749.Da  0.45
2004 Williams RW, Bennett B, Lu L, Gu J, DeFries JC, Carosone-Link PJ, Rikke BA, Belknap JK, Johnson TE. Genetic structure of the LXS panel of recombinant inbred mouse strains: a powerful resource for complex trait analysis. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 15: 637-47. PMID 15457343 DOI: 10.1007/S00335-004-2380-6  0.446
2004 Kliethermes CL, Metten P, Belknap JK, Buck KJ, Crabbe JC. Selection for pentobarbital withdrawal severity: correlated differences in withdrawal from other sedative drugs. Brain Research. 1009: 17-25. PMID 15120579 DOI: 10.1016/J.Brainres.2004.02.040  0.431
2004 Fehr C, Shirley RL, Metten P, Kosobud AE, Belknap JK, Crabbe JC, Buck KJ. Potential pleiotropic effects of Mpdz on vulnerability to seizures. Genes, Brain, and Behavior. 3: 8-19. PMID 14960011 DOI: 10.1111/J.1601-183X.2004.00035.X  0.445
2004 Klein RF, Allard J, Avnur Z, Nikolcheva T, Rotstein D, Carlos AS, Shea M, Waters RV, Belknap JK, Peltz G, Orwoll ES. Regulation of bone mass in mice by the lipoxygenase gene Alox15. Science (New York, N.Y.). 303: 229-32. PMID 14716014 DOI: 10.1126/science.1090985  0.363
2004 Mueller JL, Ellenberger EA, Vaughn LK, Belknap JK, Quock RM. Detection and mapping of quantitative trait loci that determine responsiveness of mice to nitrous oxide antinociception. Neuroscience. 123: 743-9. PMID 14706786 DOI: 10.1016/J.Neuroscience.2003.10.020  0.413
2004 Hitzemann R, Reed C, Malanger B, Lawler M, Hitzemann B, Cunningham B, McWeeney S, Belknap J, Harrington C, Buck K, Phillips T, Crabbe J. Erratum: On the integration of alcohol-related quantitative trait loci and gene expression analyses (Alcoholism: Clinical and Experimental Research 28:10 (1437-1444)) Alcoholism: Clinical and Experimental Research. 28. DOI: 10.1097/00000374-200412000-00019  0.33
2004 Buck K, Shirley R, Walter N, Fehr C, Hood H, Reilly M, Kozell L, Metten P, Crabbe J, Belknap J. GENETIC CONTROL OF PHYSICAL DEPENDENCE AND WITHDRAWAL IN MICE. Alcoholism: Clinical & Experimental Research. 28: 63A. DOI: 10.1097/00000374-200408002-00338  0.403
2004 Hood HM, Metten P, Luscher B, Crabbe JC, Belknap JK, Buck KJ. THE GABAA RECEPTOR ??2 SUBUNIT GENE MAY UNDERLIE AN ETHANOL WITHDRAWAL QTL. Alcoholism: Clinical & Experimental Research. 28: 29A. DOI: 10.1097/00000374-200408002-00133  0.351
2003 Phillips TJ, Belknap JK, Hitzemann RJ, Buck KJ, Cunningham CL, Crabbe JC. Internet resources for genomic, bioinformatics, and medical genetics information. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Appendix 5A. PMID 18428575 DOI: 10.1002/0471142301.Nsa05As22  0.369
2003 Belknap JK. Chromosome substitution strains: some quantitative considerations for genome scans and fine mapping. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 14: 723-32. PMID 14722722 DOI: 10.1007/s00335-003-2264-1  0.425
2003 Abiola O, Angel JM, Avner P, Bachmanov AA, Belknap JK, Bennett B, Blankenhorn EP, Blizard DA, Bolivar V, Brockmann GA, Buck KJ, Bureau JF, Casley WL, Chesler EJ, Cheverud JM, et al. The nature and identification of quantitative trait loci: a community's view. Nature Reviews. Genetics. 4: 911-6. PMID 14634638 DOI: 10.1038/Nrg1206  0.365
2003 Sedelis M, Hofele K, Schwarting RK, Huston JP, Belknap JK. Chromosomal loci influencing the susceptibility to the parkinsonian neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8247-53. PMID 12967986 DOI: 10.1523/Jneurosci.23-23-08247.2003  0.411
2003 Bergeson SE, Kyle Warren R, Crabbe JC, Metten P, Gene Erwin V, Belknap JK. Chromosomal loci influencing chronic alcohol withdrawal severity. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 14: 454-63. PMID 12925894 DOI: 10.1007/S00335-002-2254-4  0.466
2002 Phillips TJ, Belknap JK, Hitzemann RJ, Buck KJ, Cunningham CL, Crabbe JC. Harnessing the mouse to unravel the genetics of human disease. Genes, Brain, and Behavior. 1: 14-26. PMID 12886946 DOI: 10.1046/J.1601-1848.2001.00011.X  0.426
2002 Klein RF, Turner RJ, Skinner LD, Vartanian KA, Serang M, Carlos AS, Shea M, Belknap JK, Orwoll ES. Mapping quantitative trait loci that influence femoral cross-sectional area in mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 1752-60. PMID 12369778 DOI: 10.1359/jbmr.2002.17.10.1752  0.46
2002 Crabbe JC, Metten P, Gallaher EJ, Belknap JK. Genetic determinants of sensitivity to pentobarbital in inbred mice. Psychopharmacology. 161: 408-16. PMID 12073169 DOI: 10.1007/S00213-002-1042-1  0.431
2002 Phillips TJ, Belknap JK. Complex-trait genetics: emergence of multivariate strategies. Nature Reviews. Neuroscience. 3: 478-85. PMID 12042883 DOI: 10.1038/nrn847  0.377
2002 Fehr C, Shirley RL, Belknap JK, Crabbe JC, Buck KJ. Congenic mapping of alcohol and pentobarbital withdrawal liability loci to a <1 centimorgan interval of murine chromosome 4: identification of Mpdz as a candidate gene. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3730-8. PMID 11978849 DOI: 10.1523/Jneurosci.22-09-03730.2002  0.433
2002 Wilson SG, Chesler EJ, Hain H, Rankin AJ, Schwarz JZ, Call SB, Murray MR, West EE, Teuscher C, Rodriguez-Zas S, Belknap JK, Mogil JS. Identification of quantitative trait loci for chemical/inflammatory nociception in mice. Pain. 96: 385-91. PMID 11973013 DOI: 10.1016/S0304-3959(01)00489-4  0.485
2001 Belknap JK, Atkins AL. The replicability of QTLs for murine alcohol preference drinking behavior across eight independent studies. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 12: 893-9. PMID 11707775 DOI: 10.1007/s00335-001-2074-2  0.479
2001 Orwoll ES, Belknap JK, Klein RF. Gender specificity in the genetic determinants of peak bone mass. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 16: 1962-71. PMID 11697792 DOI: 10.1359/jbmr.2001.16.11.1962  0.43
2001 Klein OF, Carlos AS, Vartanian KA, Chambers VK, Turner EJ, Phillips TJ, Belknap JK, Orwoll ES. Confirmation and fine mapping of chromosomal regions influencing peak bone mass in mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 16: 1953-61. PMID 11697791 DOI: 10.1359/jbmr.2001.16.11.1953  0.469
2001 Hood HM, Belknap JK, Crabbe JC, Buck KJ. Genomewide search for epistasis in a complex trait: pentobarbital withdrawal convulsions in mice. Behavior Genetics. 31: 93-100. PMID 11529278 DOI: 10.1023/A:1010214026692  0.503
2001 Belknap JK, Hitzemann R, Crabbe JC, Phillips TJ, Buck KJ, Williams RW. QTL analysis and genomewide mutagenesis in mice: complementary genetic approaches to the dissection of complex traits. Behavior Genetics. 31: 5-15. PMID 11529275 DOI: 10.1023/A:1010249607128  0.467
2001 Atkins AL, Helms ML, O'Toole LA, Belknap JK. Stereotypic behaviors in mice selectively bred for high and low methamphetamine-induced stereotypic chewing. Psychopharmacology. 157: 96-104. PMID 11512049 DOI: 10.1007/s002130100774  0.374
2001 Janowsky A, Mah C, Johnson RA, Cunningham CL, Phillips TJ, Crabbe JC, Eshleman AJ, Belknap JK. Mapping genes that regulate density of dopamine transporters and correlated behaviors in recombinant inbred mice. The Journal of Pharmacology and Experimental Therapeutics. 298: 634-43. PMID 11454925  0.336
2001 Bergeson SE, Helms ML, O'Toole LA, Jarvis MW, Hain HS, Mogil JS, Belknap JK. Quantitative trait loci influencing morphine antinociception in four mapping populations. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 12: 546-53. PMID 11420618 DOI: 10.1007/S003350020022  0.442
2001 Klein RF, Shea M, Gunness ME, Pelz GB, Belknap JK, Orwoll ES. Phenotypic characterization of mice bred for high and low peak bone mass. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 16: 63-71. PMID 11149491 DOI: 10.1359/jbmr.2001.16.1.63  0.389
2001 Mason JN, Eshleman AJ, Belknap JK, Crabbe JC, Loftis JM, Macey TA, Janowsky A. NMDA Receptor Subunit mRNA and Protein Expression in Ethanol‐Withdrawal Seizure‐Prone and ‐Resistant Mice Alcoholism: Clinical and Experimental Research. 25: 651-660. DOI: 10.1111/J.1530-0277.2001.Tb02263.X  0.363
2001 Belknap JK. Behavioral screening of mutant mice Trends in Neurosciences. 24: 301-302. DOI: 10.1016/S0166-2236(00)01736-7  0.305
2000 Mogil JS, Grisel JE, Hayward MD, Bales JR, Rubinstein M, Belknap JK, Low MJ. Disparate spinal and supraspinal opioid antinociceptive responses in beta-endorphin-deficient mutant mice. Neuroscience. 101: 709-17. PMID 11113319 DOI: 10.1016/S0306-4522(00)00422-X  0.33
2000 Risinger FO, Quick E, Belknap JK. Quantitative trait loci for acute behavioral sensitivity to paraoxon. Neurotoxicology and Teratology. 22: 667-74. PMID 11106859 DOI: 10.1016/S0892-0362(00)00085-4  0.483
2000 Hatton DC, Qi Y, Belknap JK. Heritability of the blood pressure response to acute ethanol exposure in five inbred strains of mice. Alcoholism, Clinical and Experimental Research. 24: 1483-7. PMID 11045854 DOI: 10.1111/J.1530-0277.2000.Tb04564.X  0.433
1999 Grisel JE, Mogil JS, Grahame NJ, Rubinstein M, Belknap JK, Crabbe JC, Low MJ. Ethanol oral self-administration is increased in mutant mice with decreased beta-endorphin expression. Brain Research. 835: 62-7. PMID 10448196 DOI: 10.1016/S0006-8993(99)01384-0  0.383
1999 Buck K, Metten P, Belknap J, Crabbe J. Quantitative trait loci affecting risk for pentobarbital withdrawal map near alcohol withdrawal loci on mouse chromosomes 1, 4, and 11. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 10: 431-7. PMID 10337613 DOI: 10.1007/S003359901018  0.469
1999 Mogil JS, Wilson SG, Bon K, Lee SE, Chung K, Raber P, Pieper JO, Hain HS, Belknap JK, Hubert L, Elmer GI, Chung JM, Devor M. Heritability of nociception II. 'Types' of nociception revealed by genetic correlation analysis. Pain. 80: 83-93. PMID 10204720 DOI: 10.1016/S0304-3959(98)00196-1  0.422
1999 Mogil JS, Wilson SG, Bon K, Lee SE, Chung K, Raber P, Pieper JO, Hain HS, Belknap JK, Hubert L, Elmer GI, Chung JM, Devor M. Heritability of nociception I: responses of 11 inbred mouse strains on 12 measures of nociception. Pain. 80: 67-82. PMID 10204719 DOI: 10.1016/S0304-3959(98)00197-3  0.414
1999 Crabbe JC, Phillips TJ, Buck KJ, Cunningham CL, Belknap JK. Identifying genes for alcohol and drug sensitivity: recent progress and future directions. Trends in Neurosciences. 22: 173-9. PMID 10203855 DOI: 10.1016/S0166-2236(99)01393-4  0.419
1999 Kest B, Jenab S, Brodsky M, Sadowski B, Belknap JK, Mogil JS, Inturrisi CE. Mu and delta opioid receptor analgesia, binding density, and mRNA levels in mice selectively bred for high and low analgesia. Brain Research. 816: 381-9. PMID 9878841 DOI: 10.1016/S0006-8993(98)01141-X  0.374
1998 Metten P, Phillips TJ, Crabbe JC, Tarantino LM, McClearn GE, Plomin R, Erwin VG, Belknap JK. High genetic susceptibility to ethanol withdrawal predicts low ethanol consumption. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 9: 983-90. PMID 9880664 DOI: 10.1007/S003359900911  0.5
1998 Phillips TJ, Belknap JK, Buck KJ, Cunningham CL. Genes on mouse chromosomes 2 and 9 determine variation in ethanol consumption. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 9: 936-41. PMID 9880656 DOI: 10.1007/S003359900903  0.381
1998 Kest B, McLemore GL, Sadowski B, Mogil JS, Belknap JK, Inturrisi CE. Acute morphine dependence in mice selectively-bred for high and low analgesia. Neuroscience Letters. 256: 120-2. PMID 9853718 DOI: 10.1016/S0304-3940(98)00772-1  0.384
1998 Klein RF, Mitchell SR, Phillips TJ, Belknap JK, Orwoll ES. Quantitative trait loci affecting peak bone mineral density in mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 13: 1648-56. PMID 9797472 DOI: 10.1359/jbmr.1998.13.11.1648  0.462
1998 Metten P, Belknap JK, Crabbe JC. Drug withdrawal convulsions and susceptibility to convulsants after short-term selective breeding for acute ethanol withdrawal. Behavioural Brain Research. 95: 113-22. PMID 9754883 DOI: 10.1016/S0166-4328(97)00216-7  0.443
1998 Crabbe JC, Gallaher EJ, Cross SJ, Belknap JK. Genetic determinants of sensitivity to diazepam in inbred mice. Behavioral Neuroscience. 112: 668-77. PMID 9676982 DOI: 10.1037/0735-7044.112.3.668  0.436
1998 Belknap JK. Effect of within-strain sample size on QTL detection and mapping using recombinant inbred mouse strains. Behavior Genetics. 28: 29-38. PMID 9573644 DOI: 10.1023/A:1021404714631  0.381
1998 Belknap JK, Riggan J, Cross S, Young ER, Gallaher EJ, Crabbe JC. Genetic determinants of morphine activity and thermal responses in 15 inbred mouse strains. Pharmacology, Biochemistry, and Behavior. 59: 353-60. PMID 9476981 DOI: 10.1016/S0091-3057(97)00421-8  0.404
1998 Crabbe JC, Belknap JK, Metten P, Grisel JE, Buck KJ. Quantitative trait loci: mapping drug and alcohol-related genes. Advances in Pharmacology (San Diego, Calif.). 42: 1033-7. PMID 9328074 DOI: 10.1016/S1054-3589(08)60923-0  0.461
1997 Mogil JS, Richards SP, O'Toole LA, Helms ML, Mitchell SR, Kest B, Belknap JK. Identification of a sex-specific quantitative trait locus mediating nonopioid stress-induced analgesia in female mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 7995-8002. PMID 9315917 DOI: 10.1523/Jneurosci.17-20-07995.1997  0.429
1997 Crawley JN, Belknap JK, Collins A, Crabbe JC, Frankel W, Henderson N, Hitzemann RJ, Maxson SC, Miner LL, Silva AJ, Wehner JM, Wynshaw-Boris A, Paylor R. Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies. Psychopharmacology. 132: 107-24. PMID 9266608 DOI: 10.1007/S002130050327  0.447
1997 Mogil JS, Richards SP, O'Toole LA, Helms ML, Mitchell SR, Belknap JK. Genetic sensitivity to hot-plate nociception in DBA/2J and C57BL/6J inbred mouse strains: possible sex-specific mediation by delta2-opioid receptors. Pain. 70: 267-77. PMID 9150302 DOI: 10.1016/S0304-3959(97)03333-2  0.456
1997 Belknap JK, Richards SP, O'Toole LA, Helms ML, Phillips TJ. Short-term selective breeding as a tool for QTL mapping: ethanol preference drinking in mice. Behavior Genetics. 27: 55-66. PMID 9145544 DOI: 10.1023/A:1025615409383  0.463
1997 Buck KJ, Metten P, Belknap JK, Crabbe JC. Quantitative trait loci involved in genetic predisposition to acute alcohol withdrawal in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 3946-55. PMID 9133412 DOI: 10.1523/Jneurosci.17-10-03946.1997  0.446
1997 Grisel JE, Belknap JK, O'Toole LA, Helms ML, Wenger CD, Crabbe JC. Quantitative trait loci affecting methamphetamine responses in BXD recombinant inbred mouse strains. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 745-54. PMID 8987796 DOI: 10.1523/Jneurosci.17-02-00745.1997  0.479
1997 Mogil JS, Belknap JK. Sex and genotype determine the selective activation of neurochemically-distinct mechanisms of swim stress-induced analgesia. Pharmacology, Biochemistry, and Behavior. 56: 61-6. PMID 8981610 DOI: 10.1016/S0091-3057(96)00157-8  0.416
1996 Mayeda AR, Hofstetter JR, Belknap JK, Nurnberger JI. Hypothetical quantitative trait loci (QTL) for circadian period of locomotor activity in CXB recombinant inbred strains of mice. Behavior Genetics. 26: 505-11. PMID 8917949 DOI: 10.1007/Bf02359755  0.442
1996 Mogil JS, Grisel JE, Zhangs G, Belknap JK, Grandy DK. Functional antagonism of mu-, delta- and kappa-opioid antinociception by orphanin FQ. Neuroscience Letters. 214: 131-4. PMID 8878101 DOI: 10.1016/0304-3940(96)12917-7  0.305
1996 Quock RM, Mueller JL, Vaughn LK, Belknap JK. Nitrous oxide antinociception in BXD recombinant inbred mouse strains and identification of quantitative trait loci. Brain Research. 725: 23-9. PMID 8828582 DOI: 10.1016/S0006-8993(96)00211-9  0.434
1996 Belknap JK, Mitchell SR, O'Toole LA, Helms ML, Crabbe JC. Type I and type II error rates for quantitative trait loci (QTL) mapping studies using recombinant inbred mouse strains. Behavior Genetics. 26: 149-60. PMID 8639150 DOI: 10.1007/BF02359892  0.386
1996 Mogil JS, Kest B, Sadowski B, Belknap JK. Differential genetic mediation of sensitivity to morphine in genetic models of opiate antinociception: influence of nociceptive assay. The Journal of Pharmacology and Experimental Therapeutics. 276: 532-44. PMID 8632319  0.358
1996 Gallaher EJ, Jones GE, Belknap JK, Crabbe JC. Identification of genetic markers for initial sensitivity and rapid tolerance to ethanol-induced ataxia using quantitative trait locus analysis in BXD recombinant inbred mice. The Journal of Pharmacology and Experimental Therapeutics. 277: 604-12. PMID 8627537  0.399
1996 Mogil JS, Sternberg WF, Marek P, Sadowski B, Belknap JK, Liebeskind JC. The genetics of pain and pain inhibition. Proceedings of the National Academy of Sciences of the United States of America. 93: 3048-55. PMID 8610166 DOI: 10.1073/pnas.93.7.3048  0.305
1995 Roberts AJ, Phillips TJ, Belknap JK, Finn DA, Keith LD. Genetic analysis of the corticosterone response to ethanol in BXD recombinant inbred mice. Behavioral Neuroscience. 109: 1199-208. PMID 8748968  0.401
1995 Tarricone BJ, Hwang WG, Hingtgen JN, Mitchell SR, Belknap JK, Nurnberger JI. Identification of a locus on mouse chromosome 17 associated with high-affinity choline uptake using BXD recombinant inbred mice and quantitative trait loci analysis. Genomics. 27: 161-4. PMID 7665164 DOI: 10.1006/geno.1995.1019  0.433
1995 Belknap JK, Mogil JS, Helms ML, Richards SP, O'Toole LA, Bergeson SE, Buck KJ. Localization to chromosome 10 of a locus influencing morphine analgesia in crosses derived from C57BL/6 and DBA/2 strains. Life Sciences. 57: PL117-24. PMID 7643715 DOI: 10.1016/0024-3205(95)02040-P  0.446
1995 Mogil JS, Flodman P, Spence MA, Sternberg WF, Kest B, Sadowski B, Liebeskind JC, Belknap JK. Oligogenic determination of morphine analgesic magnitude: a genetic analysis of selectively bred mouse lines. Behavior Genetics. 25: 397-406. PMID 7575370 DOI: 10.1007/Bf02197290  0.418
1995 Carter LA, Belknap JK, Crabbe JC, Janowsky A. Allosteric regulation of the N-methyl-D-aspartate receptor-linked ion channel complex and effects of ethanol in ethanol-withdrawal seizure-prone and -resistant mice. Journal of Neurochemistry. 64: 213-9. PMID 7528263 DOI: 10.1046/J.1471-4159.1995.64010213.X  0.324
1995 Tarricone BJ, Hingtgen JN, Belknap JK, Mitchell SR, Nurnberger JI. Quantitative trait loci associated with the behavioral response of B x D recombinant inbred mice to restraint stress: a preliminary communication. Behavior Genetics. 25: 489-95. PMID 7487846 DOI: 10.1007/BF02253378  0.459
1994 Crabbe JC, Belknap JK, Buck KJ, Metten P. Use of recombinant inbred strains for studying genetic determinants of responses to alcohol. Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement. 2: 67-71. PMID 8974318  0.444
1994 Crabbe JC, Belknap JK, Buck KJ. Genetic animal models of alcohol and drug abuse. Science (New York, N.Y.). 264: 1715-23. PMID 8209252 DOI: 10.1126/Science.8209252  0.375
1994 Crabbe JC, Gallaher ES, Phillips TJ, Belknap JK. Genetic determinants of sensitivity to ethanol in inbred mice. Behavioral Neuroscience. 108: 186-95. PMID 8192844 DOI: 10.1037//0735-7044.108.1.186  0.43
1994 Crabbe JC, Belknap JK, Mitchell SR, Crawshaw LI. Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice. The Journal of Pharmacology and Experimental Therapeutics. 269: 184-92. PMID 8169823  0.396
1994 Mogil JS, Marek P, O'Toole LA, Helms ML, Sadowski B, Liebeskind JC, Belknap JK. Mu-opiate receptor binding is up-regulated in mice selectively bred for high stress-induced analgesia. Brain Research. 653: 16-22. PMID 7982048 DOI: 10.1016/0006-8993(94)90366-2  0.386
1994 Phillips TJ, Crabbe JC, Metten P, Belknap JK. Localization of genes affecting alcohol drinking in mice. Alcoholism, Clinical and Experimental Research. 18: 931-41. PMID 7978106 DOI: 10.1111/J.1530-0277.1994.Tb00062.X  0.431
1993 Belknap JK, Metten P, Helms ML, O'Toole LA, Angeli-Gade S, Crabbe JC, Phillips TJ. Quantitative trait loci (QTL) applications to substances of abuse: physical dependence studies with nitrous oxide and ethanol in BXD mice. Behavior Genetics. 23: 213-22. PMID 8512534 DOI: 10.1007/Bf01067426  0.494
1993 Marek P, Mogil JS, Belknap JK, Sadowski B, Liebeskind JC. Levorphanol and swim stress-induced analgesia in selectively bred mice: evidence for genetic commonalities. Brain Research. 608: 353-7. PMID 8495369 DOI: 10.1016/0006-8993(93)91479-C  0.39
1993 Crabbe JC, Merrill CM, Belknap JK. Effect of acute alcohol withdrawal on sensitivity to pro- and anticonvulsant treatments in WSP mice. Alcoholism, Clinical and Experimental Research. 17: 1233-9. PMID 8116837 DOI: 10.1111/J.1530-0277.1993.Tb05235.X  0.42
1993 Belknap JK, Crabbe JC, Young ER. Voluntary consumption of ethanol in 15 inbred mouse strains. Psychopharmacology. 112: 503-10. PMID 7871064 DOI: 10.1007/BF02244901  0.387
1993 Belknap JK, Crabbe JC, Riggan J, O'Toole LA. Voluntary consumption of morphine in 15 inbred mouse strains. Psychopharmacology. 112: 352-8. PMID 7871041 DOI: 10.1007/BF02244932  0.403
1993 Crabbe JC, Belknap JK. Behavior genetic analyses of drug withdrawal. Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement. 2: 477-82. PMID 7748342  0.429
1992 Belknap JK, Crabbe JC. Chromosome mapping of gene loci affecting morphine and amphetamine responses in BXD recombinant inbred mice. Annals of the New York Academy of Sciences. 654: 311-23. PMID 1632590 DOI: 10.1111/J.1749-6632.1992.Tb25977.X  0.438
1992 Crabbe JC, Phillips TJ, Cunningham CL, Belknap JK. Genetic determinants of ethanol reinforcement. Annals of the New York Academy of Sciences. 654: 302-10. PMID 1632589 DOI: 10.1111/J.1749-6632.1992.Tb25976.X  0.467
1992 Crabbe JC, Belknap JK. Genetic approaches to drug dependence. Trends in Pharmacological Sciences. 13: 212-9. PMID 1604714 DOI: 10.1016/0165-6147(92)90066-F  0.348
1992 Belknap JK, Crabbe JC, Plomin R, McClearn GE, Sampson KE, O'Toole LA, Gora-Maslak G. Single-locus control of saccharin intake in BXD/Ty recombinant inbred (RI) mice: some methodological implications for RI strain analysis. Behavior Genetics. 22: 81-100. PMID 1590732 DOI: 10.1007/Bf01066794  0.453
1992 Belknap JK, Phillips TJ, O'Toole LA. Quantitative trait loci associated with brain weight in the BXD/Ty recombinant inbred mouse strains. Brain Research Bulletin. 29: 337-44. PMID 1393606 DOI: 10.1016/0361-9230(92)90065-6  0.394
1992 Belknap JK. Empirical estimates of Bonferroni corrections for use in chromosome mapping studies with the BXD recombinant inbred strains. Behavior Genetics. 22: 677-84. PMID 1290453 DOI: 10.1007/BF01066638  0.358
1991 Phillips TJ, Belknap JK, Crabbe JC. Use of recombinant inbred strains to assess vulnerability to drug abuse at the genetic level. Journal of Addictive Diseases. 10: 73-87. PMID 2065120 DOI: 10.1300/J069v10n01_06  0.495
1991 Belknap JK, Akers TK. Genetic commonalities between ethanol-induced LORR (loss of righting reflex) and LORR due to nitrous oxide, argon and nitrogen. Annals of the New York Academy of Sciences. 625: 558-60. PMID 2058909 DOI: 10.1111/J.1749-6632.1991.Tb33890.X  0.336
1991 Crabbe JC, Merrill CD, Belknap JK. Effects of convulsants on handling-induced convulsions in mice selected for ethanol withdrawal severity. Brain Research. 550: 1-6. PMID 1888987 DOI: 10.1016/0006-8993(91)90397-E  0.406
1991 Gora-Maslak G, McClearn GE, Crabbe JC, Phillips TJ, Belknap JK, Plomin R. Use of recombinant inbred strains to identify quantitative trait loci in psychopharmacology. Psychopharmacology. 104: 413-24. PMID 1780413 DOI: 10.1007/Bf02245643  0.49
1991 Belknap JK, Laursen SE, Sampson KE, Wilkie A. Where are the mu receptors that mediate opioid analgesia? An autoradiographic study in the HAR and LAR selection lines. Journal of Addictive Diseases. 10: 29-44. PMID 1648410 DOI: 10.1300/J069v10n01_03  0.382
1990 Crabbe JC, Merrill CM, Kim D, Belknap JK. Alcohol dependence and withdrawal: a genetic animal model. Annals of Medicine. 22: 259-63. PMID 2248762 DOI: 10.3109/07853899009148937  0.456
1990 Crabbe JC, Phillips TJ, Kosobud A, Belknap JK. Estimation of genetic correlation: interpretation of experiments using selectively bred and inbred animals. Alcoholism, Clinical and Experimental Research. 14: 141-51. PMID 2190477 DOI: 10.1111/J.1530-0277.1990.Tb00461.X  0.401
1989 Crabbe JC, Belknap JK, Young ER. Sensitivity to the anticonvulsant effects of ethanol and pentobarbital in mouse lines genetically selected for ethanol sensitivity. Alcoholism, Clinical and Experimental Research. 13: 291-4. PMID 2658670  0.315
1986 Crabbe JC, Young ER, Tam B, Kosobud A, Belknap JK, Laursen SE. Genetic differences in anticonvulsant sensitivity in mouse lines selectively bred for ethanol withdrawal severity. The Journal of Pharmacology and Experimental Therapeutics. 239: 154-9. PMID 3093669  0.321
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