| Year |
Citation |
Score |
| 2024 |
Yu H, Chiang A, Rubinstein M, Low MJ. The homeodomain transcription factor Six3 regulates hypothalamic Pomc expression and its absence from POMC neurons induces hyperphagia and mild obesity in male mice. Molecular Metabolism. 101993. PMID 39025297 DOI: 10.1016/j.molmet.2024.101993 |
0.585 |
|
| 2024 |
Rojo D, Hael CE, Soria A, de Souza FSJ, Low MJ, Franchini LF, Rubinstein M. A mammalian tripartite enhancer cluster controls hypothalamic expression, food intake, and body weight. Proceedings of the National Academy of Sciences of the United States of America. 121: e2322692121. PMID 38652744 DOI: 10.1073/pnas.2322692121 |
0.572 |
|
| 2023 |
Castell L, Le Gall V, Cutando L, Petit CP, Puighermanal E, Makrini-Malville L, Kim HR, Jercog D, Tarot P, Tassou A, Harrus AG, Rubinstein M, Nouvian R, Rivat C, Besnard A, et al. Dopamine D2 receptors in WFS1-neurons regulate food-seeking and avoidance behaviors. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110883. PMID 37858736 DOI: 10.1016/j.pnpbp.2023.110883 |
0.322 |
|
| 2022 |
Ferré S, Belcher AM, Bonaventura J, Quiroz C, Sánchez-Soto M, Casadó-Anguera V, Cai NS, Moreno E, Boateng CA, Keck TM, Florán B, Earley CJ, Ciruela F, Casadó V, Rubinstein M, et al. Functional and pharmacological role of the dopamine D receptor and its polymorphic variants. Frontiers in Endocrinology. 13: 1014678. PMID 36267569 DOI: 10.3389/fendo.2022.1014678 |
0.311 |
|
| 2022 |
Cutando L, Puighermanal E, Castell L, Tarot P, Belle M, Bertaso F, Arango-Lievano M, Ango F, Rubinstein M, Quintana A, Chédotal A, Mameli M, Valjent E. Cerebellar dopamine D2 receptors regulate social behaviors. Nature Neuroscience. PMID 35710984 DOI: 10.1038/s41593-022-01092-8 |
0.308 |
|
| 2022 |
Casey E, Avale ME, Kravitz A, Rubinstein M. Partial Ablation of Postsynaptic Dopamine D2 Receptors in the Central Nucleus of the Amygdala Increases Risk Avoidance in Exploratory Tasks. Eneuro. 9. PMID 35210287 DOI: 10.1523/ENEURO.0528-21.2022 |
0.376 |
|
| 2022 |
Lee GS, Graham DL, Noble BL, Trammell TS, McCarthy DM, Anderson LR, Rubinstein M, Bhide PG, Stanwood GD. Behavioral and Neuroanatomical Consequences of Cell-Type Specific Loss of Dopamine D2 Receptors in the Mouse Cerebral Cortex. Frontiers in Behavioral Neuroscience. 15: 815713. PMID 35095443 DOI: 10.3389/fnbeh.2021.815713 |
0.334 |
|
| 2022 |
Yu H, Rubinstein M, Low MJ. Developmental single-cell transcriptomics of hypothalamic POMC neurons reveal the genetic trajectories of multiple neuropeptidergic phenotypes. Elife. 11. PMID 35044906 DOI: 10.7554/eLife.72883 |
0.54 |
|
| 2021 |
Casadó-Anguera V, Moreno E, Sánchez-Soto M, Cai NS, Bonaventura J, Homar-Ruano P, Rubinstein M, Cortés A, Canela EI, Ferré S, Casadó V. Heteromerization between α adrenoceptors and different polymorphic variants of the dopamine D receptor determines pharmacological and functional differences. Implications for impulsive-control disorders. Pharmacological Research. 105745. PMID 34182128 DOI: 10.1016/j.phrs.2021.105745 |
0.323 |
|
| 2020 |
Puighermanal E, Castell L, Esteve-Codina A, Melser S, Kaganovsky K, Zussy C, Boubaker-Vitre J, Gut M, Rialle S, Kellendonk C, Sanz E, Quintana A, Marsicano G, Martin M, Rubinstein M, et al. Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum. Nature Communications. 11: 1957. PMID 32327644 DOI: 10.1038/S41467-020-15716-9 |
0.337 |
|
| 2020 |
Trotta M, Bello EP, Alsina R, Tavella MB, Ferrán JL, Rubinstein M, Bumaschny VF. Hypothalamic Pomc expression restricted to GABAergic neurons suppresses Npy overexpression and restores food intake in obese mice. Molecular Metabolism. 100985. PMID 32311511 DOI: 10.1016/J.Molmet.2020.100985 |
0.401 |
|
| 2020 |
Hael CE, Rojo D, Orquera DP, Low MJ, Rubinstein M. The transcriptional regulator PRDM12 is critical for Pomc expression in the mouse hypothalamus and controlling food intake, adiposity, and body weight. Molecular Metabolism. 34: 43-53. PMID 32180559 DOI: 10.1016/j.molmet.2020.01.007 |
0.548 |
|
| 2020 |
Yu H, Thompson Z, Kiran S, Jones GL, Mundada L, Gahlot S, Rubinstein M, Low MJ. Expression of a hypomorphic Pomc allele alters leptin dynamics during late pregnancy. The Journal of Endocrinology. PMID 32027603 DOI: 10.1530/JOE-19-0576 |
0.549 |
|
| 2020 |
Yu H, Jones G, Thompson Z, Rubinstein M, Low MJ. MON-709 Single-Cell RNA-Sequencing Deciphers POMC Neuron Destiny Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1333 |
0.583 |
|
| 2019 |
Bocarsly ME, da Silva E Silva D, Kolb V, Luderman KD, Shashikiran S, Rubinstein M, Sibley DR, Dobbs LK, Alvarez VA. A Mechanism Linking Two Known Vulnerability Factors for Alcohol Abuse: Heightened Alcohol Stimulation and Low Striatal Dopamine D2 Receptors. Cell Reports. 29: 1147-1163.e5. PMID 31665630 DOI: 10.1016/J.Celrep.2019.09.059 |
0.381 |
|
| 2019 |
Orquera DP, Tavella MB, de Souza FSJ, Nasif S, Low MJ, Rubinstein M. The homeodomain transcription factor NKX2.1 is essential for the early specification of melanocortin neuron identity and activates expression in the developing hypothalamus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30886014 DOI: 10.1523/JNEUROSCI.2924-18.2019 |
0.558 |
|
| 2019 |
Cromberg LE, Saez TMM, Otero MG, Tomasella E, Alloatti M, Damianich A, Devoto VP, Ferrario J, Gelman D, Rubinstein M, Falzone TL. Neuronal KIF5b deletion induces striatum-dependent locomotor impairments and defects in membrane presentation of dopamine D2 receptors. Journal of Neurochemistry. PMID 30664247 DOI: 10.1111/Jnc.14665 |
0.781 |
|
| 2017 |
Steyn FJ, Ngo ST, Chen VP, Bailey-Downs LC, Xie TY, Ghadami M, Brimijoin S, Freeman WM, Rubinstein M, Low MJ, Stout MB. 17α-estradiol acts through hypothalamic pro-opiomelanocortin expressing neurons to reduce feeding behavior. Aging Cell. PMID 29168299 DOI: 10.1111/acel.12703 |
0.488 |
|
| 2017 |
Zhou Y, Rubinstein M, Low M, Kreek MJ. V1b receptor antagonist SSR149415 and naltrexone synergistically decrease excessive alcohol drinking in male and female mice. Alcoholism, Clinical and Experimental Research. PMID 29105118 DOI: 10.1111/Acer.13544 |
0.541 |
|
| 2017 |
Burke LK, Ogunnowo-Bada E, Georgescu T, Cristiano C, de Morentin PBM, Valencia Torres L, D'Agostino G, Riches C, Heeley N, Ruan Y, Rubinstein M, Low MJ, Myers MG, Rochford JJ, Evans ML, et al. Lorcaserin improves glycemic control via a melanocortin neurocircuit. Molecular Metabolism. 6: 1092-1102. PMID 29031711 DOI: 10.1016/J.Molmet.2017.07.004 |
0.515 |
|
| 2017 |
Rubinstein M, Low MJ. Molecular and functional genetics of the proopiomelanocortin gene, food intake regulation and obesity. Febs Letters. PMID 28771698 DOI: 10.1002/1873-3468.12776 |
0.516 |
|
| 2017 |
Bonaventura J, Quiroz C, Cai NS, Rubinstein M, Tanda G, Ferré S. Key role of the dopamine D4 receptor in the modulation of corticostriatal glutamatergic neurotransmission. Science Advances. 3: e1601631. PMID 28097219 DOI: 10.1126/Sciadv.1601631 |
0.444 |
|
| 2016 |
Friend DM, Devarakonda K, O'Neal TJ, Skirzewski M, Papazoglou I, Kaplan AR, Liow JS, Guo J, Rane SG, Rubinstein M, Alvarez VA, Hall KD, Kravitz AV. Basal Ganglia Dysfunction Contributes to Physical Inactivity in Obesity. Cell Metabolism. PMID 28041956 DOI: 10.1016/J.Cmet.2016.12.001 |
0.305 |
|
| 2016 |
Zhou Y, Rubinstein M, Low MJ, Kreek MJ. Hypothalamic-specific proopiomelanocortin-deficiency reduces alcohol drinking in male and female mice. Genes, Brain, and Behavior. PMID 27870313 DOI: 10.1111/Gbb.12362 |
0.527 |
|
| 2016 |
Luque GM, Lopez-Vicchi F, Ornstein AM, Brie B, De Winne C, Fiore E, Perez Millan MI, Mazzolini G, Rubinstein M, Becu-Villalobos D. Chronic hyperprolactinemia evoked by disruption of lactotrope dopamine D2 receptors impacts on liver and adipocyte genes related to glucose and insulin balance. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00200.2016. PMID 27802964 DOI: 10.1152/Ajpendo.00200.2016 |
0.375 |
|
| 2016 |
Chhabra KH, Adams JM, Jones GL, Yamashita M, Schlapschy M, Skerra A, Rubinstein M, Low MJ. Reprogramming the body weight set point by a reciprocal interaction of hypothalamic leptin sensitivity and Pomc gene expression reverts extreme obesity. Molecular Metabolism. 5: 869-81. PMID 27689000 DOI: 10.1016/j.molmet.2016.07.012 |
0.498 |
|
| 2016 |
Orquera DP, Nasif S, Low MJ, Rubinstein M, de Souza FS. Essential function of the transcription factor Rax in the early patterning of the mammalian hypothalamus. Developmental Biology. PMID 27212025 DOI: 10.1016/j.ydbio.2016.05.021 |
0.507 |
|
| 2016 |
Lemos JC, Friend DM, Kaplan AR, Shin JH, Rubinstein M, Kravitz AV, Alvarez VA. Enhanced GABA Transmission Drives Bradykinesia Following Loss of Dopamine D2 Receptor Signaling. Neuron. 90: 824-838. PMID 27196975 DOI: 10.1016/J.Neuron.2016.04.040 |
0.319 |
|
| 2016 |
Burke LK, Doslikova B, D'Agostino G, Greenwald-Yarnell M, Georgescu T, Chianese R, Martinez de Morentin PB, Ogunnowo-Bada E, Cansell C, Valencia-Torres L, Garfield AS, Apergis-Schoute J, Lam DD, Speakman JR, Rubinstein M, et al. Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons. Molecular Metabolism. 5: 245-52. PMID 26977396 DOI: 10.1016/J.Molmet.2016.01.005 |
0.693 |
|
| 2016 |
Burke LK, Doslikova B, D'Agostino G, Greenwald-Yarnell M, Georgescu T, Chianese R, Martinez de Morentin PB, Ogunnowo-Bada E, Cansell C, Valencia-Torres L, Garfield AS, Apergis-Schoute J, Lam DD, Speakman JR, Rubinstein M, et al. Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons Molecular Metabolism. 5: 245-252. DOI: 10.1016/j.molmet.2016.01.005 |
0.675 |
|
| 2015 |
Chhabra KH, Adams JM, Fagel B, Lam DD, Qi N, Rubinstein M, Low MJ. Hypothalamic POMC-deficiency improves glucose tolerance despite insulin resistance by increasing glycosuria. Diabetes. PMID 26467632 DOI: 10.2337/Db15-0804 |
0.677 |
|
| 2015 |
Nasif S, de Souza FS, González LE, Yamashita M, Orquera DP, Low MJ, Rubinstein M. Islet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood. Proceedings of the National Academy of Sciences of the United States of America. 112: E1861-70. PMID 25825735 DOI: 10.1073/pnas.1500672112 |
0.576 |
|
| 2015 |
Lam DD, de Souza FS, Nasif S, Yamashita M, López-Leal R, Otero-Corchon V, Meece K, Sampath H, Mercer AJ, Wardlaw SL, Rubinstein M, Low MJ. Partially redundant enhancers cooperatively maintain Mammalian pomc expression above a critical functional threshold. Plos Genetics. 11: e1004935. PMID 25671638 DOI: 10.1371/Journal.Pgen.1004935 |
0.796 |
|
| 2015 |
Lam DD, Attard CA, Mercer AJ, Myers MG, Rubinstein M, Low MJ. Conditional expression of Pomc in the Lepr-positive subpopulation of POMC neurons is sufficient for normal energy homeostasis and metabolism. Endocrinology. 156: 1292-302. PMID 25594696 DOI: 10.1210/En.2014-1373 |
0.808 |
|
| 2015 |
Holroyd KB, Adrover MF, Fuino RL, Bock R, Kaplan AR, Gremel CM, Rubinstein M, Alvarez VA. Loss of feedback inhibition via D2 autoreceptors enhances acquisition of cocaine taking and reactivity to drug-paired cues. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1495-509. PMID 25547712 DOI: 10.1038/Npp.2014.336 |
0.354 |
|
| 2015 |
Ramirez MC, Ornstein AM, Luque GM, Perez Millan MI, Garcia-Tornadu I, Rubinstein M, Becu-Villalobos D. Pituitary and brain dopamine D2 receptors regulate liver gene sexual dimorphism. Endocrinology. 156: 1040-51. PMID 25545383 DOI: 10.1210/En.2014-1714 |
0.353 |
|
| 2015 |
Rocchetti J, Isingrini E, Dal Bo G, Sagheby S, Menegaux A, Tronche F, Levesque D, Moquin L, Gratton A, Wong TP, Rubinstein M, Giros B. Presynaptic D2 dopamine receptors control long-term depression expression and memory processes in the temporal hippocampus. Biological Psychiatry. 77: 513-25. PMID 24742619 DOI: 10.1016/J.Biopsych.2014.03.013 |
0.368 |
|
| 2015 |
Zhou Y, Rubinstein M, Low MJ, Kreek MJ. Alcohol drinking and related behaviors in hypothalamic-specific Pomc-deficient mice Drug and Alcohol Dependence. 146: e31-e32. DOI: 10.1016/J.Drugalcdep.2014.09.766 |
0.48 |
|
| 2014 |
Burke LK, Doslikova B, D'Agostino G, Garfield AS, Farooq G, Burdakov D, Low MJ, Rubinstein M, Evans ML, Billups B, Heisler LK. 5-HT obesity medication efficacy via POMC activation is maintained during aging. Endocrinology. 155: 3732-8. PMID 25051442 DOI: 10.1210/En.2014-1223 |
0.483 |
|
| 2014 |
Perez Millan MI, Luque GM, Ramirez MC, Noain D, Ornstein AM, Rubinstein M, Becu-Villalobos D. Selective disruption of dopamine D2 receptors in pituitary lactotropes increases body weight and adiposity in female mice. Endocrinology. 155: 829-39. PMID 24424036 DOI: 10.1210/En.2013-1707 |
0.442 |
|
| 2013 |
Domené S, Bumaschny VF, de Souza FS, Franchini LF, Nasif S, Low MJ, Rubinstein M. Enhancer turnover and conserved regulatory function in vertebrate evolution. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20130027. PMID 24218639 DOI: 10.1098/Rstb.2013.0027 |
0.587 |
|
| 2013 |
NoaÃn D, Pérez-Millán MI, Bello EP, Luque GM, Casas Cordero R, Gelman DM, Peper M, Tornadu IG, Low MJ, Becú-Villalobos D, Rubinstein M. Central dopamine D2 receptors regulate growth-hormone-dependent body growth and pheromone signaling to conspecific males. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 5834-42. PMID 23536095 DOI: 10.1523/Jneurosci.5673-12.2013 |
0.6 |
|
| 2012 |
Bumaschny VF, Yamashita M, Casas-Cordero R, Otero-Corchón V, de Souza FS, Rubinstein M, Low MJ. Obesity-programmed mice are rescued by early genetic intervention. The Journal of Clinical Investigation. 122: 4203-12. PMID 23093774 DOI: 10.1172/Jci62543 |
0.541 |
|
| 2012 |
Franchini LF, de Souza FS, Low MJ, Rubinstein M. Positive selection of co-opted mobile genetic elements in a mammalian gene: If you can't beat them, join them. Mobile Genetic Elements. 2: 106-109. PMID 22934245 DOI: 10.4161/Mge.20267 |
0.616 |
|
| 2012 |
González S, Rangel-Barajas C, Peper M, Lorenzo R, Moreno E, Ciruela F, Borycz J, Ortiz J, LluÃs C, Franco R, McCormick PJ, Volkow ND, Rubinstein M, Floran B, Ferré S. Dopamine D4 receptor, but not the ADHD-associated D4.7 variant, forms functional heteromers with the dopamine D2S receptor in the brain. Molecular Psychiatry. 17: 650-62. PMID 21844870 DOI: 10.1038/Mp.2011.93 |
0.429 |
|
| 2011 |
Franchini LF, López-Leal R, Nasif S, Beati P, Gelman DM, Low MJ, de Souza FJ, Rubinstein M. Convergent evolution of two mammalian neuronal enhancers by sequential exaptation of unrelated retroposons. Proceedings of the National Academy of Sciences of the United States of America. 108: 15270-5. PMID 21876128 DOI: 10.1073/Pnas.1104997108 |
0.613 |
|
| 2011 |
Rubinstein M, Low MJ. The smoking gun in nicotine-induced anorexia. Cell Metabolism. 14: 145-7. PMID 21803282 DOI: 10.1016/J.Cmet.2011.07.006 |
0.528 |
|
| 2011 |
Bello EP, Mateo Y, Gelman DM, Noaín D, Shin JH, Low MJ, Alvarez VA, Lovinger DM, Rubinstein M. Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors. Nature Neuroscience. 14: 1033-8. PMID 21743470 DOI: 10.1038/Nn.2862 |
0.659 |
|
| 2011 |
Lee AK, Smart JL, Rubinstein M, Low MJ, Tse A. Reciprocal regulation of TREK-1 channels by arachidonic acid and CRH in mouse corticotropes. Endocrinology. 152: 1901-10. PMID 21343252 DOI: 10.1210/En.2010-1066 |
0.633 |
|
| 2011 |
Franchini LF, López-Leal R, Nasif S, Beati P, Gelman DM, Low MJ, De Souza FJS, Rubinstein M. Convergent evolution of two mammalian neuronal enhancers by sequential exaptation of unrelated retroposons (Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 37 (15270-15275)) Proceedings of the National Academy of Sciences of the United States of America. 108: 20850. DOI: 10.1073/Pnas.1119060109 |
0.521 |
|
| 2010 |
Michaelides M, Pascau J, Gispert JD, Delis F, Grandy DK, Wang GJ, Desco M, Rubinstein M, Volkow ND, Thanos PK. Dopamine D4 receptors modulate brain metabolic activity in the prefrontal cortex and cerebellum at rest and in response to methylphenidate. The European Journal of Neuroscience. 32: 668-76. PMID 20646063 DOI: 10.1111/J.1460-9568.2010.07319.X |
0.421 |
|
| 2010 |
GarcÃa-Tornadu I, Risso G, Perez-Millan MI, Noain D, Diaz-Torga G, Low MJ, Rubinstein M, Becu-Villalobos D. Neurotransmitter modulation of the GHRH-GH axis. Frontiers of Hormone Research. 38: 59-69. PMID 20616496 DOI: 10.1159/000318495 |
0.63 |
|
| 2010 |
Thanos PK, Bermeo C, Rubinstein M, Suchland KL, Wang GJ, Grandy DK, Volkow ND. Conditioned place preference and locomotor activity in response to methylphenidate, amphetamine and cocaine in mice lacking dopamine D4 receptors. Journal of Psychopharmacology (Oxford, England). 24: 897-904. PMID 19282420 DOI: 10.1177/0269881109102613 |
0.439 |
|
| 2009 |
Nemirovsky SI, Avale ME, Brunner D, Rubinstein M. Reward-seeking and discrimination deficits displayed by hypodopaminergic mice are prevented in mice lacking dopamine D4 receptors. Synapse (New York, N.Y.). 63: 991-7. PMID 19598175 DOI: 10.1002/Syn.20680 |
0.431 |
|
| 2008 |
Guo C, Qiu HY, Shi M, Huang Y, Johnson RL, Rubinstein M, Chen SD, Ding YQ. Lmx1b-controlled isthmic organizer is essential for development of midbrain dopaminergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 14097-106. PMID 19109492 DOI: 10.1523/Jneurosci.3267-08.2008 |
0.442 |
|
| 2008 |
Gong L, Yao F, Hockman K, Heng HH, Morton GJ, Takeda K, Akira S, Low MJ, Rubinstein M, MacKenzie RG. Signal transducer and activator of transcription-3 is required in hypothalamic agouti-related protein/neuropeptide Y neurons for normal energy homeostasis. Endocrinology. 149: 3346-54. PMID 18403487 DOI: 10.1210/En.2007-0945 |
0.625 |
|
| 2008 |
Kelly MA, Low MJ, Rubinstein M, Phillips TJ. Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice. Genes, Brain, and Behavior. 7: 568-77. PMID 18363855 DOI: 10.1111/J.1601-183X.2008.00392.X |
0.66 |
|
| 2007 |
Santangelo AM, de Souza FS, Franchini LF, Bumaschny VF, Low MJ, Rubinstein M. Ancient exaptation of a CORE-SINE retroposon into a highly conserved mammalian neuronal enhancer of the proopiomelanocortin gene. Plos Genetics. 3: 1813-26. PMID 17922573 DOI: 10.1371/Journal.Pgen.0030166 |
0.571 |
|
| 2007 |
Bumaschny VF, de Souza FS, López Leal RA, Santangelo AM, Baetscher M, Levi DH, Low MJ, Rubinstein M. Transcriptional regulation of pituitary POMC is conserved at the vertebrate extremes despite great promoter sequence divergence. Molecular Endocrinology (Baltimore, Md.). 21: 2738-49. PMID 17698954 DOI: 10.1210/Me.2006-0557 |
0.565 |
|
| 2007 |
Wedemeyer C, Goutman JD, Avale ME, Franchini LF, Rubinstein M, Calvo DJ. Functional activation by central monoamines of human dopamine D(4) receptor polymorphic variants coupled to GIRK channels in Xenopus oocytes. European Journal of Pharmacology. 562: 165-73. PMID 17350612 DOI: 10.1016/J.Ejphar.2007.01.055 |
0.444 |
|
| 2006 |
NoaÃn D, Avale ME, Wedemeyer C, Calvo D, Peper M, Rubinstein M. Identification of brain neurons expressing the dopamine D4 receptor gene using BAC transgenic mice. The European Journal of Neuroscience. 24: 2429-38. PMID 17100831 DOI: 10.1111/j.1460-9568.2006.05148.x |
0.402 |
|
| 2006 |
GarcÃa-Tornadú I, Rubinstein M, Gaylinn BD, Hill D, Arany E, Low MJ, DÃaz-Torga G, Becu-Villalobos D. GH in the dwarf dopaminergic D2 receptor knockout mouse: somatotrope population, GH release, and responsiveness to GH-releasing factors and somatostatin. The Journal of Endocrinology. 190: 611-9. PMID 17003262 DOI: 10.1677/Joe.1.06902 |
0.628 |
|
| 2006 |
Cristina C, GarcÃa-Tornadú I, DÃaz-Torga G, Rubinstein M, Low MJ, Becú-Villalobos D. Dopaminergic D2 receptor knockout mouse: an animal model of prolactinoma. Frontiers of Hormone Research. 35: 50-63. PMID 16809922 DOI: 10.1159/000094308 |
0.588 |
|
| 2005 |
Elmer GI, Pieper JO, Levy J, Rubinstein M, Low MJ, Grandy DK, Wise RA. Brain stimulation and morphine reward deficits in dopamine D2 receptor-deficient mice. Psychopharmacology. 182: 33-44. PMID 16136297 DOI: 10.1007/S00213-005-0051-2 |
0.576 |
|
| 2005 |
de Souza FS, Bumaschny VF, Low MJ, Rubinstein M. Subfunctionalization of expression and peptide domains following the ancient duplication of the proopiomelanocortin gene in teleost fishes. Molecular Biology and Evolution. 22: 2417-27. PMID 16093565 DOI: 10.1093/Molbev/Msi236 |
0.482 |
|
| 2005 |
Thanos PK, Rivera SN, Weaver K, Grandy DK, Rubinstein M, Umegaki H, Wang GJ, Hitzemann R, Volkow ND. Dopamine D2R DNA transfer in dopamine D2 receptor-deficient mice: effects on ethanol drinking. Life Sciences. 77: 130-9. PMID 15862598 DOI: 10.1016/J.Lfs.2004.10.061 |
0.408 |
|
| 2005 |
Cristina C, DÃaz-Torga G, Baldi A, Góngora A, Rubinstein M, Low MJ, Becú-Villalobos D. Increased pituitary vascular endothelial growth factor-a in dopaminergic D2 receptor knockout female mice. Endocrinology. 146: 2952-62. PMID 15817666 DOI: 10.1210/En.2004-1445 |
0.595 |
|
| 2005 |
de Souza FS, Santangelo AM, Bumaschny V, Avale ME, Smart JL, Low MJ, Rubinstein M. Identification of neuronal enhancers of the proopiomelanocortin gene by transgenic mouse analysis and phylogenetic footprinting. Molecular and Cellular Biology. 25: 3076-86. PMID 15798195 DOI: 10.1128/Mcb.25.8.3076-3086.2005 |
0.706 |
|
| 2004 |
Overstreet LS, Hentges ST, Bumaschny VF, de Souza FS, Smart JL, Santangelo AM, Low MJ, Westbrook GL, Rubinstein M. A transgenic marker for newly born granule cells in dentate gyrus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3251-9. PMID 15056704 DOI: 10.1523/Jneurosci.5173-03.2004 |
0.786 |
|
| 2004 |
Gan L, Falzone TL, Zhang K, Rubinstein M, Baldessarini RJ, Tarazi FI. Enhanced expression of dopamine D(1) and glutamate NMDA receptors in dopamine D(4) receptor knockout mice. Journal of Molecular Neuroscience : Mn. 22: 167-78. PMID 14997010 DOI: 10.1385/Jmn:22:3:167 |
0.753 |
|
| 2004 |
Narayanan S, Lam H, Christian L, Levine MS, Grandy D, Rubinstein M, Maidment NT. Endogenous opioids mediate basal hedonic tone independent of dopamine D-1 or D-2 receptor activation. Neuroscience. 124: 241-6. PMID 14960355 DOI: 10.1016/J.Neuroscience.2003.11.011 |
0.464 |
|
| 2004 |
Avale ME, Falzone TL, Gelman DM, Low MJ, Grandy DK, Rubinstein M. The dopamine D4 receptor is essential for hyperactivity and impaired behavioral inhibition in a mouse model of attention deficit/hyperactivity disorder. Molecular Psychiatry. 9: 718-26. PMID 14699433 DOI: 10.1038/Sj.Mp.4001474 |
0.765 |
|
| 2004 |
Tomiyama K, McNamara FN, Clifford JJ, Kinsella A, Drago J, Fuchs S, Grandy DK, Low MJ, Rubinstein M, Tighe O, Croke DT, Koshikawa N, Waddington JL. Comparative phenotypic resolution of spontaneous, D2-like and D1-like agonist-induced orofacial movement topographies in congenic mutants with dopamine D2 vs. D3 receptor "knockout". Synapse (New York, N.Y.). 51: 71-81. PMID 14579426 DOI: 10.1002/Syn.10284 |
0.605 |
|
| 2003 |
Franchini LF, Rubinstein M, Vivas L. Reduced sodium appetite and increased oxytocin gene expression in mutant mice lacking beta-endorphin. Neuroscience. 121: 875-81. PMID 14580937 DOI: 10.1016/S0306-4522(03)00485-8 |
0.392 |
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| 2003 |
Gelman DM, NoaÃn D, Avale ME, Otero V, Low MJ, Rubinstein M. Transgenic mice engineered to target Cre/loxP-mediated DNA recombination into catecholaminergic neurons. Genesis (New York, N.Y. : 2000). 36: 196-202. PMID 12929090 DOI: 10.1002/Gene.10217 |
0.577 |
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| 2003 |
Low MJ, Hayward MD, Appleyard SM, Rubinstein M. State-dependent modulation of feeding behavior by proopiomelanocortin-derived beta-endorphin. Annals of the New York Academy of Sciences. 994: 192-201. PMID 12851316 DOI: 10.1111/J.1749-6632.2003.Tb03180.X |
0.574 |
|
| 2003 |
Heisler LK, Cowley MA, Kishi T, Tecott LH, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro J, Zigman JM, Cone RD, Elmquist JK. Central serotonin and melanocortin pathways regulating energy homeostasis. Annals of the New York Academy of Sciences. 994: 169-74. PMID 12851313 DOI: 10.1111/J.1749-6632.2003.Tb03177.X |
0.646 |
|
| 2003 |
Katz JL, Chausmer AL, Elmer GI, Rubinstein M, Low MJ, Grandy DK. Cocaine-induced locomotor activity and cocaine discrimination in dopamine D4 receptor mutant mice. Psychopharmacology. 170: 108-14. PMID 12783155 DOI: 10.1007/S00213-003-1513-Z |
0.577 |
|
| 2003 |
Appleyard SM, Hayward M, Young JI, Butler AA, Cone RD, Rubinstein M, Low MJ. A role for the endogenous opioid beta-endorphin in energy homeostasis. Endocrinology. 144: 1753-60. PMID 12697680 DOI: 10.1210/En.2002-221096 |
0.557 |
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| 2003 |
Ibrahim N, Bosch MA, Smart JL, Qiu J, Rubinstein M, Rønnekleiv OK, Low MJ, Kelly MJ. Hypothalamic proopiomelanocortin neurons are glucose responsive and express K(ATP) channels. Endocrinology. 144: 1331-40. PMID 12639916 DOI: 10.1210/En.2002-221033 |
0.683 |
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| 2002 |
Ensinck JW, Baskin DG, Vahl TP, Vogel RE, Laschansky EC, Francis BH, Hoffman RC, Krakover JD, Stamm MR, Low MJ, Rubinstein M, Otero-Corchon V, D'Alessio DA. Thrittene, Homologous with Somatostatin-28(1-13), Is a Novel Peptide in Mammalian Gut and Circulation. Endocrinology. 143: 2599-2609. PMID 28201530 DOI: 10.1210/endo.143.7.8904 |
0.414 |
|
| 2002 |
Refojo D, Kovalovsky D, Young JI, Rubinstein M, Holsboer F, Reul JM, Low MJ, Arzt E. Increased splenocyte proliferative response and cytokine production in beta-endorphin-deficient mice. Journal of Neuroimmunology. 131: 126-34. PMID 12458044 DOI: 10.1016/S0165-5728(02)00268-0 |
0.476 |
|
| 2002 |
Thanos PK, Taintor NB, Alexoff D, Vaska P, Logan J, Grandy DK, Fang Y, Lee JH, Fowler JS, Volkow ND, Rubinstein M. In vivo comparative imaging of dopamine D2 knockout and wild-type mice with (11)C-raclopride and microPET. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 43: 1570-7. PMID 12411561 |
0.33 |
|
| 2002 |
Chausmer AL, Elmer GI, Rubinstein M, Low MJ, Grandy DK, Katz JL. Cocaine-induced locomotor activity and cocaine discrimination in dopamine D2 receptor mutant mice. Psychopharmacology. 163: 54-61. PMID 12185400 DOI: 10.1007/s00213-002-1142-y |
0.558 |
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| 2002 |
RamÃrez JL, Mouchantaf R, Kumar U, Otero Corchon V, Rubinstein M, Low MJ, Patel YC. Brain somatostatin receptors are up-regulated in somatostatin-deficient mice. Molecular Endocrinology (Baltimore, Md.). 16: 1951-63. PMID 12145348 DOI: 10.1210/Me.2002-0068 |
0.607 |
|
| 2002 |
Heisler LK, Cowley MA, Tecott LH, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro JB, Marcus JN, Holstege H, Lee CE, Cone RD, Elmquist JK. Activation of central melanocortin pathways by fenfluramine. Science (New York, N.Y.). 297: 609-11. PMID 12142539 DOI: 10.1126/Science.1072327 |
0.659 |
|
| 2002 |
Li X, Bek M, Asico LD, Yang Z, Rubinstein M, Grandy DK, Goldstein DS, Eisner GM, Jose PA. [Disruption of the D(2) dopamine receptor produces adrenergic and endothelin B receptor-dependent hypertension]. Zhonghua Yi Xue Za Zhi. 82: 703-7. PMID 12133472 |
0.336 |
|
| 2002 |
Ensinck JW, Baskin DG, Vahl TP, Vogel RE, Laschansky EC, Francis BH, Hoffman RC, Krakover JD, Stamm MR, Low MJ, Rubinstein M, Otero-Corchon V, D'Alessio DA. Thrittene, homologous with somatostatin-28((1-13)), is a novel peptide in mammalian gut and circulation. Endocrinology. 143: 2599-609. PMID 12072392 DOI: 10.1210/Endo.143.7.8904 |
0.542 |
|
| 2002 |
Elmer GI, Pieper JO, Rubinstein M, Low MJ, Grandy DK, Wise RA. Failure of intravenous morphine to serve as an effective instrumental reinforcer in dopamine D2 receptor knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: RC224. PMID 12006606 |
0.584 |
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| 2002 |
Díaz-Torga G, Feierstein C, Libertun C, Gelman D, Kelly MA, Low MJ, Rubinstein M, Becú-Villalobos D. Disruption of the D2 dopamine receptor alters GH and IGF-I secretion and causes dwarfism in male mice. Endocrinology. 143: 1270-9. PMID 11897683 DOI: 10.1210/Endo.143.4.8750 |
0.58 |
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| 2002 |
Nir I, Harrison JM, Haque R, Low MJ, Grandy DK, Rubinstein M, Iuvone PM. Dysfunctional light-evoked regulation of cAMP in photoreceptors and abnormal retinal adaptation in mice lacking dopamine D4 receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2063-73. PMID 11896146 DOI: 10.1523/Jneurosci.22-06-02063.2002 |
0.634 |
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| 2002 |
Falzone TL, Gelman DM, Young JI, Grandy DK, Low MJ, Rubinstein M. Absence of dopamine D4 receptors results in enhanced reactivity to unconditioned, but not conditioned, fear. The European Journal of Neuroscience. 15: 158-64. PMID 11860516 DOI: 10.1046/J.0953-816X.2001.01842.X |
0.793 |
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| 2002 |
Buckmaster PS, Otero-Corchón V, Rubinstein M, Low MJ. Heightened seizure severity in somatostatin knockout mice. Epilepsy Research. 48: 43-56. PMID 11823109 DOI: 10.1016/S0920-1211(01)00318-7 |
0.55 |
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| 2001 |
Li XX, Bek M, Asico LD, Yang Z, Grandy DK, Goldstein DS, Rubinstein M, Eisner GM, Jose PA. Adrenergic and endothelin B receptor-dependent hypertension in dopamine receptor type-2 knockout mice. Hypertension. 38: 303-8. PMID 11566895 DOI: 10.1161/01.Hyp.38.3.303 |
0.356 |
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| 2001 |
Clifford JJ, Kinsella A, Tighe O, Rubinstein M, Grandy DK, Low MJ, Croke DT, Waddington JL. Comparative, topographically-based evaluation of behavioural phenotype and specification of D(1)-like:D(2) interactions in a line of incipient congenic mice with D(2) dopamine receptor 'knockout'. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 25: 527-36. PMID 11557166 DOI: 10.1016/S0893-133X(01)00246-9 |
0.64 |
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| 2001 |
Low MJ, Otero-Corchon V, Parlow AF, Ramirez JL, Kumar U, Patel YC, Rubinstein M. Somatostatin is required for masculinization of growth hormone-regulated hepatic gene expression but not of somatic growth. The Journal of Clinical Investigation. 107: 1571-80. PMID 11413165 DOI: 10.1172/Jci11941 |
0.561 |
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| 2001 |
Cowley MA, Smart JL, Rubinstein M, Cerdán MG, Diano S, Horvath TL, Cone RD, Low MJ. Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature. 411: 480-4. PMID 11373681 DOI: 10.1038/35078085 |
0.701 |
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| 2001 |
Rubinstein M, Cepeda C, Hurst RS, Flores-Hernandez J, Ariano MA, Falzone TL, Kozell LB, Meshul CK, Bunzow JR, Low MJ, Levine MS, Grandy DK. Dopamine D4 receptor-deficient mice display cortical hyperexcitability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 3756-63. PMID 11356863 DOI: 10.1523/Jneurosci.21-11-03756.2001 |
0.804 |
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| 2001 |
Dockstader CL, Rubinstein M, Grandy DK, Low MJ, van der Kooy D. The D2 receptor is critical in mediating opiate motivation only in opiate-dependent and withdrawn mice. The European Journal of Neuroscience. 13: 995-1001. PMID 11264672 DOI: 10.1046/J.1460-9568.2001.01455.X |
0.646 |
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| 2001 |
Chen JF, Moratalla R, Impagnatiello F, Grandy DK, Cuellar B, Rubinstein M, Beilstein MA, Hackett E, Fink JS, Low MJ, Ongini E, Schwarzschild MA. The role of the D(2) dopamine receptor (D(2)R) in A(2A) adenosine receptor (A(2A)R)-mediated behavioral and cellular responses as revealed by A(2A) and D(2) receptor knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 1970-5. PMID 11172060 DOI: 10.1073/Pnas.98.4.1970 |
0.569 |
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| 2001 |
Khan ZU, Koulen P, Rubinstein M, Grandy DK, Goldman-Rakic PS. An astroglia-linked dopamine D2-receptor action in prefrontal cortex. Proceedings of the National Academy of Sciences of the United States of America. 98: 1964-9. PMID 11172059 DOI: 10.1073/Pnas.98.4.1964 |
0.448 |
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| 2001 |
Cepeda C, Hurst RS, Altemus KL, Flores-Hernández J, Calvert CR, Jokel ES, Grandy DK, Low MJ, Rubinstein M, Ariano MA, Levine MS. Facilitated glutamatergic transmission in the striatum of D2 dopamine receptor-deficient mice. Journal of Neurophysiology. 85: 659-70. PMID 11160501 DOI: 10.1152/Jn.2001.85.2.659 |
0.66 |
|
| 2000 |
Cunningham CL, Howard MA, Gill SJ, Rubinstein M, Low MJ, Grandy DK. Ethanol-conditioned place preference is reduced in dopamine D2 receptor-deficient mice. Pharmacology, Biochemistry, and Behavior. 67: 693-9. PMID 11166059 DOI: 10.1016/S0091-3057(00)00414-7 |
0.621 |
|
| 2000 |
Mogil JS, Grisel JE, Hayward MD, Bales JR, Rubinstein M, Belknap JK, Low MJ. Disparate spinal and supraspinal opioid antinociceptive responses in beta-endorphin-deficient mutant mice. Neuroscience. 101: 709-17. PMID 11113319 DOI: 10.1016/S0306-4522(00)00422-X |
0.517 |
|
| 2000 |
Risinger FO, Freeman PA, Rubinstein M, Low MJ, Grandy DK. Lack of operant ethanol self-administration in dopamine D2 receptor knockout mice. Psychopharmacology. 152: 343-50. PMID 11105945 DOI: 10.1007/S002130000548 |
0.536 |
|
| 2000 |
Tseng KY, Roubert C, Do L, Rubinstein M, Kelly MA, Grandy DK, Low MJ, Gershanik OS, Murer MG, Giros B, Raisman-Vozari R. Selective increase of Nurr1 mRNA expression in mesencephalic dopaminergic neurons of D2 dopamine receptor-deficient mice. Brain Research. Molecular Brain Research. 80: 1-6. PMID 11039723 DOI: 10.1016/S0169-328X(00)00107-8 |
0.779 |
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| 2000 |
Murer MG, Dziewczapolski G, Salin P, Vila M, Tseng KY, Ruberg M, Rubinstein M, Kelly MA, Grandy DK, Low MJ, Hirsch E, Raisman-Vozari R, Gershanik O. The indirect basal ganglia pathway in dopamine D(2) receptor-deficient mice. Neuroscience. 99: 643-50. PMID 10974427 DOI: 10.1016/S0306-4522(00)00223-2 |
0.824 |
|
| 2000 |
Zahniser NR, Simosky JK, Mayfield RD, Negri CA, Hanania T, Larson GA, Kelly MA, Grandy DK, Rubinstein M, Low MJ, Fredholm BB. Functional uncoupling of adenosine A(2A) receptors and reduced responseto caffeine in mice lacking dopamine D2 receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5949-57. PMID 10934242 DOI: 10.1523/Jneurosci.20-16-05949.2000 |
0.599 |
|
| 2000 |
Defagot MC, Falzone TL, Low MJ, Grandy DK, Rubinstein M, Antonelli MC. Quantitative analysis of the dopamine D4 receptor in the mouse brain. Journal of Neuroscience Research. 59: 202-8. PMID 10650878 DOI: 10.1002/(Sici)1097-4547(20000115)59:2<202::Aid-Jnr6>3.0.Co;2-5 |
0.768 |
|
| 1999 |
Menalled LB, Dziewczapolski G, Garcia MC, Rubinstein M, Gershanik OS. D3 receptor knockdown through antisense oligonucleotide administration supports its inhibitory role in locomotion. Neuroreport. 10: 3131-6. PMID 10574548 DOI: 10.1097/00001756-199910190-00002 |
0.809 |
|
| 1999 |
Grisel JE, Mogil JS, Grahame NJ, Rubinstein M, Belknap JK, Crabbe JC, Low MJ. Ethanol oral self-administration is increased in mutant mice with decreased beta-endorphin expression. Brain Research. 835: 62-7. PMID 10448196 DOI: 10.1016/S0006-8993(99)01384-0 |
0.574 |
|
| 1999 |
Ralph RJ, Varty GB, Kelly MA, Wang YM, Caron MG, Rubinstein M, Grandy DK, Low MJ, Geyer MA. The dopamine D2, but not D3 or D4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4627-33. PMID 10341260 DOI: 10.1523/Jneurosci.19-11-04627.1999 |
0.645 |
|
| 1999 |
Wilke RA, Lupardus PJ, Grandy DK, Rubinstein M, Low MJ, Jackson MB. K+ channel modulation in rodent neurohypophysial nerve terminals by sigma receptors and not by dopamine receptors. The Journal of Physiology. 517: 391-406. PMID 10332090 DOI: 10.1111/J.1469-7793.1999.00391.X |
0.602 |
|
| 1999 |
Dickinson SD, Sabeti J, Larson GA, Giardina K, Rubinstein M, Kelly MA, Grandy DK, Low MJ, Gerhardt GA, Zahniser NR. Dopamine D2 receptor-deficient mice exhibit decreased dopamine transporter function but no changes in dopamine release in dorsal striatum. Journal of Neurochemistry. 72: 148-56. PMID 9886065 DOI: 10.1046/J.1471-4159.1999.0720148.X |
0.654 |
|
| 1998 |
Phillips TJ, Brown KJ, Burkhart-Kasch S, Wenger CD, Kelly MA, Rubinstein M, Grandy DK, Low MJ. Alcohol preference and sensitivity are markedly reduced in mice lacking dopamine D2 receptors. Nature Neuroscience. 1: 610-5. PMID 10196569 DOI: 10.1038/2843 |
0.63 |
|
| 1998 |
Low MJ, Kelly MA, Rubinstein M, Grandy DK. Single genes and complex phenotypes. Molecular Psychiatry. 3: 373-7. PMID 9774768 DOI: 10.1038/Sj.Mp.4000455 |
0.605 |
|
| 1998 |
Young JI, Otero V, Cerdán MG, Falzone TL, Chan EC, Low MJ, Rubinstein M. Authentic cell-specific and developmentally regulated expression of pro-opiomelanocortin genomic fragments in hypothalamic and hindbrain neurons of transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6631-40. PMID 9712635 DOI: 10.1523/Jneurosci.18-17-06631.1998 |
0.787 |
|
| 1998 |
Dziewczapolski G, Menalled LB, GarcÃa MC, Mora MA, Gershanik OS, Rubinstein M. Opposite roles of D1 and D5 dopamine receptors in locomotion revealed by selective antisense oligonucleotides. Neuroreport. 9: 1-5. PMID 9592037 DOI: 10.1097/00001756-199801050-00001 |
0.803 |
|
| 1998 |
Kelly MA, Rubinstein M, Phillips TJ, Lessov CN, Burkhart-Kasch S, Zhang G, Bunzow JR, Fang Y, Gerhardt GA, Grandy DK, Low MJ. Locomotor activity in D2 dopamine receptor-deficient mice is determined by gene dosage, genetic background, and developmental adaptations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 3470-9. PMID 9547254 DOI: 10.1523/Jneurosci.18-09-03470.1998 |
0.661 |
|
| 1998 |
Cerdán MG, Young JI, Zino E, Falzone TL, Otero V, Torres HN, Rubinstein M. Accurate spatial and temporal transgene expression driven by a 3.8-kilobase promoter of the bovine beta-casein gene in the lactating mouse mammary gland. Molecular Reproduction and Development. 49: 236-45. PMID 9491375 DOI: 10.1002/(Sici)1098-2795(199803)49:3<236::Aid-Mrd3>3.0.Co;2-P |
0.713 |
|
| 1998 |
Low M, Rubinstein M, Kelly M, Phillips T, Grandy D. 263. Altered behavior in dopamine D2 and D4 receptor gene knockout mice Biological Psychiatry. 43: S79. DOI: 10.1016/S0006-3223(98)90711-9 |
0.651 |
|
| 1998 |
Low MJ, Kelly MA, Rubinstein M, Grandy DK. Single genes and complex phenotypes Molecular Psychiatry. 3: 375-377. |
0.429 |
|
| 1998 |
Phillips TJ, Brown KJ, Burkhart-Kasch S, Wenger CD, Kelly MA, Rubinstein M, Grandy DK, Low MJ. Alcohol preference and sensitivity are markedly reduced in mice lacking dopamine D2 receptors Molecular Cell. 1: 610-615. |
0.338 |
|
| 1997 |
Rubinstein M, Phillips TJ, Bunzow JR, Falzone TL, Dziewczapolski G, Zhang G, Fang Y, Larson JL, McDougall JA, Chester JA, Saez C, Pugsley TA, Gershanik O, Low MJ, Grandy DK. Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine. Cell. 90: 991-1001. PMID 9323127 DOI: 10.1016/S0092-8674(00)80365-7 |
0.807 |
|
| 1997 |
Kelly MA, Rubinstein M, Asa SL, Zhang G, Saez C, Bunzow JR, Allen RG, Hnasko R, Ben-Jonathan N, Grandy DK, Low MJ. Pituitary lactotroph hyperplasia and chronic hyperprolactinemia in dopamine D2 receptor-deficient mice. Neuron. 19: 103-13. PMID 9247267 DOI: 10.1016/S0896-6273(00)80351-7 |
0.67 |
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| 1997 |
Dziewczapolski G, Mora MA, Menalled LB, Stéfano FJ, Rubinstein M, Gershanik OS. Threshold of dopamine content and D1 receptor stimulation necessary for the expression of rotational behavior induced by D2 receptor stimulation under normo and supersensitive conditions. Naunyn-Schmiedeberg's Archives of Pharmacology. 355: 30-5. PMID 9007839 DOI: 10.1007/Pl00004914 |
0.802 |
|
| 1996 |
Rubinstein M, Mogil JS, Japón M, Chan EC, Allen RG, Low MJ. Absence of opioid stress-induced analgesia in mice lacking beta-endorphin by site-directed mutagenesis. Proceedings of the National Academy of Sciences of the United States of America. 93: 3995-4000. PMID 8633004 DOI: 10.1073/Pnas.93.9.3995 |
0.584 |
|
| 1994 |
Japón MA, Rubinstein M, Low MJ. In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 42: 1117-25. PMID 8027530 DOI: 10.1177/42.8.8027530 |
0.527 |
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| 1993 |
Rubinstein M, Japón MA, Low MJ. Introduction of a point mutation into the mouse genome by homologous recombination in embryonic stem cells using a replacement type vector with a selectable marker. Nucleic Acids Research. 21: 2613-7. PMID 8392702 DOI: 10.1093/Nar/21.11.2613 |
0.46 |
|
| 1993 |
Rubinstein M, Mortrud M, Liu B, Low MJ. Rat and mouse proopiomelanocortin gene sequences target tissue-specific expression to the pituitary gland but not to the hypothalamus of transgenic mice. Neuroendocrinology. 58: 373-80. PMID 8284022 DOI: 10.1159/000126566 |
0.609 |
|
| 1993 |
Low MJ, Liu B, Hammer GD, Rubinstein M, Allen RG. Post-translational processing of proopiomelanocortin (POMC) in mouse pituitary melanotroph tumors induced by a POMC-simian virus 40 large T antigen transgene. The Journal of Biological Chemistry. 268: 24967-75. PMID 8227058 |
0.486 |
|
| 1992 |
Rubinstein M, Liu B, Goodman RH, Low MJ. Targeted expression of somatostatin in vasopressinergic magnocellular hypothalamic neurons of transgenic mice. Molecular and Cellular Neurosciences. 3: 152-61. PMID 19912855 DOI: 10.1016/1044-7431(92)90019-X |
0.718 |
|
| 1992 |
Liu B, Hammer GD, Rubinstein M, Mortrud M, Low MJ. Identification of DNA elements cooperatively activating proopiomelanocortin gene expression in the pituitary glands of transgenic mice. Molecular and Cellular Biology. 12: 3978-90. PMID 1508198 DOI: 10.1128/Mcb.12.9.3978 |
0.571 |
|
| 1990 |
Rubinstein M, Muschietti JP, Gershanik O, Flawia MM, Stefano FJ. Adaptive mechanisms of striatal D1 and D2 dopamine receptors in response to a prolonged reserpine treatment in mice. The Journal of Pharmacology and Experimental Therapeutics. 252: 810-6. PMID 2138223 |
0.663 |
|
| 1989 |
Rubinstein M, Schinder AF, Gershanik O, Stefano FJ. Positive interaction between alpha-1 adrenergic and dopamine-2 receptors in locomotor activity of normo and supersensitive mice. Life Sciences. 44: 337-46. PMID 2536881 DOI: 10.1016/0024-3205(89)90227-0 |
0.641 |
|
| 1989 |
Gershanik OS, Rubinstein M, Stefano F. Inhibitory action of L-dopa. Neurology. 39: 1137. PMID 2527340 DOI: 10.1212/Wnl.39.8.1137-A |
0.543 |
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