Jarda T. Wroblewski - Publications

Affiliations: 
Georgetown 
Area:
Neuropharmacology, glutamate receptors
Website:
http://pharmacology.georgetown.edu/faculty/facwrobl.html

90 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Gelb T, Pshenichkin S, Hathaway HA, Grajkowska E, Dalley CB, Wolfe BB, Wroblewski JT. Atypical signaling of metabotropic glutamate receptor 1 in human melanoma cells. Biochemical Pharmacology. 98: 182-9. PMID 26291396 DOI: 10.1016/j.bcp.2015.08.091  1
2015 DiRaddo JO, Miller EJ, Bowman-Dalley C, Wroblewska B, Javidnia M, Grajkowska E, Wolfe BB, Liotta DC, Wroblewski JT. Chloride is an Agonist of Group II and III Metabotropic Glutamate Receptors. Molecular Pharmacology. 88: 450-9. PMID 26089372 DOI: 10.1124/mol.114.096420  1
2015 Hathaway HA, Pshenichkin S, Grajkowska E, Gelb T, Emery AC, Wolfe BB, Wroblewski JT. Pharmacological characterization of mGlu1 receptors in cerebellar granule cells reveals biased agonism. Neuropharmacology. 93: 199-208. PMID 25700650 DOI: 10.1016/j.neuropharm.2015.02.007  1
2015 Gelb T, Pshenichkin S, Rodriguez OC, Hathaway HA, Grajkowska E, DiRaddo JO, Wroblewska B, Yasuda RP, Albanese C, Wolfe BB, Wroblewski JT. Metabotropic glutamate receptor 1 acts as a dependence receptor creating a requirement for glutamate to sustain the viability and growth of human melanomas. Oncogene. 34: 2711-20. PMID 25065592 DOI: 10.1038/onc.2014.231  1
2014 Gelb T, Hathaway HA, Wroblewski JT. Triple threat treatment: Exploiting the dependence receptor properties of metabotropic glutamate receptor 1 against melanoma. Molecular & Cellular Oncology. 1: e969163. PMID 27308372 DOI: 10.4161/23723548.2014.969163  0.96
2014 DiRaddo JO, Miller EJ, Hathaway HA, Grajkowska E, Wroblewska B, Wolfe BB, Liotta DC, Wroblewski JT. A real-time method for measuring cAMP production modulated by Gαi/o-coupled metabotropic glutamate receptors. The Journal of Pharmacology and Experimental Therapeutics. 349: 373-82. PMID 24659805 DOI: 10.1124/jpet.113.211532  1
2013 DiRaddo JO, Pshenichkin S, Gelb T, Wroblewski JT. Two newly identified exons in human GRM1 express a novel splice variant of metabotropic glutamate 1 receptor. Gene. 519: 367-73. PMID 23481697 DOI: 10.1016/j.gene.2013.02.009  1
2012 Emery AC, DiRaddo JO, Miller E, Hathaway HA, Pshenichkin S, Takoudjou GR, Grajkowska E, Yasuda RP, Wolfe BB, Wroblewski JT. Ligand bias at metabotropic glutamate 1a receptors: molecular determinants that distinguish β-arrestin-mediated from G protein-mediated signaling. Molecular Pharmacology. 82: 291-301. PMID 22584219 DOI: 10.1124/mol.112.078444  1
2011 Pshenichkin S, Surin A, Surina E, KlauziÅ„ska M, Grajkowska E, Luchenko V, DoliÅ„ska M, Wroblewska B, Wroblewski JT. Heat shock enhances CMV-IE promoter-driven metabotropic glutamate receptor expression and toxicity in transfected cells. Neuropharmacology. 60: 1292-300. PMID 21241715 DOI: 10.1016/j.neuropharm.2011.01.010  1
2011 Nicoletti F, Bockaert J, Collingridge GL, Conn PJ, Ferraguti F, Schoepp DD, Wroblewski JT, Pin JP. Metabotropic glutamate receptors: from the workbench to the bedside. Neuropharmacology. 60: 1017-41. PMID 21036182 DOI: 10.1016/j.neuropharm.2010.10.022  1
2010 Emery AC, Pshenichkin S, Takoudjou GR, Grajkowska E, Wolfe BB, Wroblewski JT. The protective signaling of metabotropic glutamate receptor 1 Is mediated by sustained, beta-arrestin-1-dependent ERK phosphorylation. The Journal of Biological Chemistry. 285: 26041-8. PMID 20566651 DOI: 10.1074/jbc.M110.139899  1
2008 Pshenichkin S, DoliÅ„ska M, KlauziÅ„ska M, Luchenko V, Grajkowska E, Wroblewski JT. Dual neurotoxic and neuroprotective role of metabotropic glutamate receptor 1 in conditions of trophic deprivation - possible role as a dependence receptor. Neuropharmacology. 55: 500-8. PMID 18619982 DOI: 10.1016/j.neuropharm.2008.06.039  1
2007 Surin A, Pshenichkin S, Grajkowska E, Surina E, Wroblewski JT. Cyclothiazide selectively inhibits mGluR1 receptors interacting with a common allosteric site for non-competitive antagonists. Neuropharmacology. 52: 744-54. PMID 17095021 DOI: 10.1016/j.neuropharm.2006.09.018  1
2006 Iso Y, Grajkowska E, Wroblewski JT, Davis J, Goeders NE, Johnson KM, Sanker S, Roth BL, Tueckmantel W, Kozikowski AP. Synthesis and structure-activity relationships of 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine analogues as potent, noncompetitive metabotropic glutamate receptor subtype 5 antagonists; search for cocaine medications. Journal of Medicinal Chemistry. 49: 1080-100. PMID 16451073 DOI: 10.1021/jm050570f  1
2006 Makarewicz D, Gadamski R, Ziembowicz A, Kozikowski AP, Wroblewski JT, Lazarewicz JW. Neuroprotective effects of the agonist of metabotropic glutamate receptors ABHxD-I in two animal models of cerebral ischaemia. Resuscitation. 68: 119-26. PMID 16325990 DOI: 10.1016/j.resuscitation.2005.05.018  1
2005 Alagille D, Baldwin RM, Roth BL, Wroblewski JT, Grajkowska E, Tamagnan GD. Functionalization at position 3 of the phenyl ring of the potent mGluR5 noncompetitive antagonists MPEP. Bioorganic & Medicinal Chemistry Letters. 15: 945-9. PMID 15686891 DOI: 10.1016/j.bmcl.2004.12.047  1
2005 Alagille D, Baldwin RM, Roth BL, Wroblewski JT, Grajkowska E, Tamagnan GD. Synthesis and receptor assay of aromatic-ethynyl-aromatic derivatives with potent mGluR5 antagonist activity. Bioorganic & Medicinal Chemistry. 13: 197-209. PMID 15582465 DOI: 10.1016/j.bmc.2004.09.042  1
2004 Yamamoto T, Hirasawa S, Wroblewska B, Grajkowska E, Zhou J, Kozikowski A, Wroblewski J, Neale JH. Antinociceptive effects of N-acetylaspartylglutamate (NAAG) peptidase inhibitors ZJ-11, ZJ-17 and ZJ-43 in the rat formalin test and in the rat neuropathic pain model. The European Journal of Neuroscience. 20: 483-94. PMID 15233757 DOI: 10.1111/j.1460-9568.2004.03504.x  1
2004 Olszewski RT, Bukhari N, Zhou J, Kozikowski AP, Wroblewski JT, Shamimi-Noori S, Wroblewska B, Bzdega T, Vicini S, Barton FB, Neale JH. NAAG peptidase inhibition reduces locomotor activity and some stereotypes in the PCP model of schizophrenia via group II mGluR. Journal of Neurochemistry. 89: 876-85. PMID 15140187 DOI: 10.1111/j.1471-4159.2004.02358.x  1
2004 Kozikowski AP, Zhang J, Nan F, Petukhov PA, Grajkowska E, Wroblewski JT, Yamamoto T, Bzdega T, Wroblewska B, Neale JH. Synthesis of urea-based inhibitors as active site probes of glutamate carboxypeptidase II: efficacy as analgesic agents. Journal of Medicinal Chemistry. 47: 1729-38. PMID 15027864 DOI: 10.1021/jm0306226  1
2003 Shi Q, Hufeisen SJ, Wroblewski JT, Nadeau JH, Roth BL. L-homocysteine sulfinic acid and L-homocysteic acid stimulate phosphoinositide hydrolysis in rat cortical neurons. Annals of the New York Academy of Sciences. 1003: 461-3. PMID 14684489 DOI: 10.1196/annals.1300.054  1
2003 Shi Q, Savage JE, Hufeisen SJ, Rauser L, Grajkowska E, Ernsberger P, Wroblewski JT, Nadeau JH, Roth BL. L-homocysteine sulfinic acid and other acidic homocysteine derivatives are potent and selective metabotropic glutamate receptor agonists. The Journal of Pharmacology and Experimental Therapeutics. 305: 131-42. PMID 12649361 DOI: 10.1124/jpet.102.047092  1
2002 Rong SB, Zhang J, Neale JH, Wroblewski JT, Wang S, Kozikowski AP. Molecular modeling of the interactions of glutamate carboxypeptidase II with its potent NAAG-based inhibitors. Journal of Medicinal Chemistry. 45: 4140-52. PMID 12213057 DOI: 10.1021/jm010561g  1
2001 Kozikowski AP, Nan F, Conti P, Zhang J, Ramadan E, Bzdega T, Wroblewska B, Neale JH, Pshenichkin S, Wroblewski JT. Design of remarkably simple, yet potent urea-based inhibitors of glutamate carboxypeptidase II (NAALADase). Journal of Medicinal Chemistry. 44: 298-301. PMID 11462970 DOI: 10.1021/jm000406m  1
2001 Mukhopadhyaya JK, Kozikowski AP, Grajkowska E, Pshenichkin S, Wroblewski JT. Synthesis of N(1)-substituted analogues of (2R,4R)-4-amino-pyrrolidine-2,4-dicarboxylic acid as agonists, partial agonists, and antagonists of group II metabotropic glutamate receptors. Bioorganic & Medicinal Chemistry Letters. 11: 1919-24. PMID 11459661 DOI: 10.1016/S0960-894X(01)00329-8  1
2000 Nan F, Bzdega T, Pshenichkin S, Wroblewski JT, Wroblewska B, Neale JH, Kozikowski AP. Dual function glutamate-related ligands: discovery of a novel, potent inhibitor of glutamate carboxypeptidase II possessing mGluR3 agonist activity. Journal of Medicinal Chemistry. 43: 772-4. PMID 10715144 DOI: 10.1021/jm9905559  1
1999 Kozikowski AP, Araldi GL, Tückmantel W, Pshenichkin S, Surina E, Wroblewski JT. 1-amino-APDC, a partial agonist of group II metabotropic glutamate receptors with neuroprotective properties. Bioorganic & Medicinal Chemistry Letters. 9: 1721-6. PMID 10397508 DOI: 10.1016/S0960-894X(99)00266-8  1
1998 Ma D, Ma Z, Kozikowski AP, Pshenichkin S, Wroblewski JT. Synthesis and biological evaluation of two analogues of (S)-alpha-methyl-3-carboxyphenylalanine. Bioorganic & Medicinal Chemistry Letters. 8: 2447-50. PMID 9873559 DOI: 10.1016/S0960-894X(98)00409-0  1
1998 Kozikowski AP, Steensma D, Varasi M, Pshenichkin S, Surina E, Wroblewski JT. alpha-substituted quisqualic acid analogs: new metabotropic glutamate receptor group II selective antagonists. Bioorganic & Medicinal Chemistry Letters. 8: 447-52. PMID 9871596 DOI: 10.1016/S0960-894X(98)00052-3  1
1998 Kozikowski AP, Araldi GL, Flippen-Anderson J, George C, Pshenichkin S, Surina E, Wroblewski J. Synthesis and metabotropic glutamate receptor activity of a 2- aminobicyclo[3.2.0]Heptane-2,5-dicarboxylic acid, a molecule possessing an extended glutamate conformation Bioorganic and Medicinal Chemistry Letters. 8: 925-930. PMID 9871513 DOI: 10.1016/S0960-894X(98)00146-2  1
1998 Xiao Y, Meyer EL, Thompson JM, Surin A, Wroblewski J, Kellar KJ. Rat alpha3/beta4 subtype of neuronal nicotinic acetylcholine receptor stably expressed in a transfected cell line: pharmacology of ligand binding and function. Molecular Pharmacology. 54: 322-33. PMID 9687574  1
1998 Bruno V, Wroblewska B, Wroblewski JT, Fiore L, Nicoletti F. Neuroprotective activity of N-acetylaspartylglutamate in cultured cortical cells. Neuroscience. 85: 751-7. PMID 9639269 DOI: 10.1016/S0306-4522(97)00531-9  1
1998 Kozikowski AP, Steensma D, Araldi GL, Tückmantel W, Wang S, Pshenichkin S, Surina E, Wroblewski JT. Synthesis and biology of the conformationally restricted ACPD analogue, 2-aminobicyclo[2.1.1]hexane-2,5-dicarboxylic acid-I, a potent mGluR agonist. Journal of Medicinal Chemistry. 41: 1641-50. PMID 9572889 DOI: 10.1021/jm970719q  1
1997 Shchepotin IB, Soldatenkov V, Wroblewski JT, Surin A, Shabahang M, Buras RR, Nauta RJ, Pulyaeva H, Evans SR. Apoptosis induced by hyperthermia and verapamil in vitro in a human colon cancer cell line. International Journal of Hyperthermia : the Official Journal of European Society For Hyperthermic Oncology, North American Hyperthermia Group. 13: 547-57. PMID 9354939  1
1997 Wroblewska B, Wroblewski JT, Pshenichkin S, Surin A, Sullivan SE, Neale JH. N-acetylaspartylglutamate selectively activates mGluR3 receptors in transfected cells. Journal of Neurochemistry. 69: 174-81. PMID 9202308  1
1997 Ma D, Tian H, Sun H, Kozikowski AP, Pshenichkin S, Wroblewski JT. Synthesis and biological activity of cyclic analogues of MPPG and MCPG as metabotropic glutamate receptor antagonists Bioorganic and Medicinal Chemistry Letters. 7: 1195-1198. DOI: 10.1016/S0960-894X(97)00177-7  1
1997 Tückmantel W, Kozikowski AP, Wang S, Pshenichkin S, Wroblewski JT. Synthesis, molecular modeling, and biology of the 1-benzyl derivative of APDC - an apparent mGluR6 selective ligand Bioorganic and Medicinal Chemistry Letters. 7: 601-606. DOI: 10.1016/S0960-894X(97)00068-1  1
1996 Danysz W, Raulli R, Wroblewski JT. Concanavalin A enhances quisqualate-induced calcium influx in cerebellar granule cells in culture. Acta Neurobiologiae Experimentalis. 56: 649-56. PMID 8917894  1
1996 Kozikowski AP, Liao Y, Tückmantel W, Wang S, Pshenichkin S, Surin A, Thomsen C, Wroblewski JT. Synthesis and biology of the rigidified glutamate analogue, trans-2-carboxyazetidine-3-acetic acid (t-CAA) Bioorganic and Medicinal Chemistry Letters. 6: 2559-2564. DOI: 10.1016/0960-894X(96)00464-7  1
1996 Davila-Garefa MI, Xiao Y, Meyer EL, Wroblewski JT, Surin A, Kellar KJ. Regulation of non-α4/β2 high affinity nicotinic receptors in IMR-32 cells Faseb Journal. 10: A689.  1
1995 Danysz W, Wroblewski JT. Concanavalin A increases N-methyl-D-aspartate-induced Ca2+ influx in cerebellar granule cells in culture. Polish Journal of Pharmacology. 47: 31-6. PMID 7550546  1
1994 Costa E, Armstrong DM, Guidotti A, Kharlamov A, Kiedrowski L, Manev H, Polo A, Wroblewski JT. Gangliosides in the protection against glutamate excitotoxicity. Progress in Brain Research. 101: 357-73. PMID 8029464  1
1994 Raulli R, Alho H, Wroblewski JT. N-methyl-D-aspartate receptor-induced translocation of protein kinase C to the nucleus in rat cerebellar slices. Neurochemistry International. 24: 209-14. PMID 8025529 DOI: 10.1016/0197-0186(94)90077-9  1
1994 Santi MR, Ikonomovic S, Wroblewski JT, Grayson DR. Temporal and depolarization-induced changes in the absolute amounts of mRNAs encoding metabotropic glutamate receptors in cerebellar granule neurons in vitro. Journal of Neurochemistry. 63: 1207-17. PMID 7931274  1
1994 Paulsen RE, Raulli R, Grayson DR, Wroblewski JT. Acute and long-term inhibition of agonist-stimulated phosphoinositide hydrolysis by pulse treatment of cerebellar granule cells with TPA. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 22: 67-79. PMID 7916769 DOI: 10.1007/BF03160095  1
1994 Kiedrowski L, Wroblewski JT, Costa E. Intracellular sodium concentration in cultured cerebellar granule cells challenged with glutamate. Molecular Pharmacology. 45: 1050-4. PMID 7910657  1
1994 Kiedrowski L, Brooker G, Costa E, Wroblewski JT. Glutamate impairs neuronal calcium extrusion while reducing sodium gradient. Neuron. 12: 295-300. PMID 7906528 DOI: 10.1016/0896-6273(94)90272-0  1
1993 Kozikowski AP, Tückmantel W, Liao Y, Manev H, Ikonomovic S, Wroblewski JT. Synthesis and metabotropic receptor activity of the novel rigidified glutamate analogues (+)- and (-)-trans-azetidine-2,4-dicarboxylic acid and their N-methyl derivatives. Journal of Medicinal Chemistry. 36: 2706-8. PMID 8410984  1
1993 Costa E, Armstrong D, Guidotti A, Kharlamov A, Kiedrowski L, Wroblewski JT. Ganglioside GM1 and its semisynthetic lysogangliosides reduce glutamate neurotoxicity by a novel mechanism. Advances in Experimental Medicine and Biology. 341: 129-41. PMID 7906915  1
1993 Sweetnam PM, Saab OH, Wroblewski JT, Price CH, Karbon EW, Ferkany JW. The envelope glycoprotein of HIV-1 alters NMDA receptor function. The European Journal of Neuroscience. 5: 276-83. PMID 7726990  1
1993 Wroblewska B, Wroblewski JT, Saab OH, Neale JH. N-acetylaspartylglutamate inhibits forskolin-stimulated cyclic AMP levels via a metabotropic glutamate receptor in cultured cerebellar granule cells. Journal of Neurochemistry. 61: 943-8. PMID 7689644  1
1992 Lazarewicz JW, Salinska E, Wroblewski JT. NMDA receptor-mediated arachidonic acid release in neurons: role in signal transduction and pathological aspects. Advances in Experimental Medicine and Biology. 318: 73-89. PMID 1386178  1
1992 Kiedrowski L, Costa E, Wroblewski JT. In vitro interaction between cerebellar astrocytes and granule cells: a putative role for nitric oxide. Neuroscience Letters. 135: 59-61. PMID 1371859 DOI: 10.1016/0304-3940(92)90135-T  1
1992 Kiedrowski L, Costa E, Wroblewski JT. Glutamate receptor agonists stimulate nitric oxide synthase in primary cultures of cerebellar granule cells. Journal of Neurochemistry. 58: 335-41. PMID 1370078  1
1992 Kiedrowski L, Costa E, Wroblewski JT. Sodium nitroprusside inhibits N-methyl-D-aspartate-evoked calcium influx via a nitric oxide- and cGMP-independent mechanism. Molecular Pharmacology. 41: 779-84. PMID 1314946  1
1991 Kiedrowski L, Manev H, Costa E, Wroblewski JT. Inhibition of glutamate-induced cell death by sodium nitroprusside is not mediated by nitric oxide. Neuropharmacology. 30: 1241-3. PMID 1685560 DOI: 10.1016/0028-3908(91)90171-7  1
1991 Raulli R, Danysz W, Wroblewski JT. Pretreatment of cerebellar granule cells with concanavalin A potentiates quisqualate-stimulated phosphoinositide hydrolysis. Journal of Neurochemistry. 56: 2116-24. PMID 1674000 DOI: 10.1111/j.1471-4159.1991.tb03474.x  1
1991 Raulli R, Wroblewski JT. Stimulation of phosphoinositide hydrolysis by ibotenic acid in cerebellar neurons via two glutamate receptor subtypes Drug Development Research. 24: 375-384.  1
1990 Lazarewicz JW, Wroblewski JT, Costa E. N-methyl-D-aspartate-sensitive glutamate receptors induce calcium-mediated arachidonic acid release in primary cultures of cerebellar granule cells. Journal of Neurochemistry. 55: 1875-81. PMID 2172463  1
1990 Manev H, Costa E, Wroblewski JT, Guidotti A. Abusive stimulation of excitatory amino acid receptors: a strategy to limit neurotoxicity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 4: 2789-97. PMID 2165013  1
1990 Kozikowski AP, Tückmantel W, Reynolds IJ, Wroblewski JT. Synthesis and bioactivity of a new class of rigid glutamate analogues. Modulators of the N-methyl-D-aspartate receptor. Journal of Medicinal Chemistry. 33: 1561-71. PMID 2160533  1
1990 Danysz W, Fadda E, Wroblewski JT, Costa E. [3H]D-serine labels strychnine-insensitive glycine recognition sites of rat central nervous system. Life Sciences. 46: 155-64. PMID 2154648 DOI: 10.1016/0024-3205(90)90100-6  1
1989 Hynie S, Wroblewski JT, Costa E. Profile of phosphatidylinositol metabolism stimulated by carbachol and glutamate in primary cultures of rat cerebellar neurons. Neuropharmacology. 28: 1309-15. PMID 2615914 DOI: 10.1016/0028-3908(89)90004-X  1
1989 Danysz W, Fadda E, Wroblewski JT, Costa E. Different modes of action of 3-amino-1-hydroxy-2-pyrrolidone (HA-966) and 7-chlorokynurenic acid in the modulation of N-methyl-D-aspartate-sensitive glutamate receptors. Molecular Pharmacology. 36: 912-6. PMID 2574820  1
1989 Danysz W, Fadda E, Wroblewski JT, Costa E. Kynurenate and 2-amino-5-phosphonovalerate interact with multiple binding sites of the N-methyl-D-aspartate-sensitive glutamate receptor domain. Neuroscience Letters. 96: 340-4. PMID 2566140 DOI: 10.1016/0304-3940(89)90402-3  1
1989 Wroblewski JT, Danysz W. Modulation of glutamate receptors: molecular mechanisms and functional implications. Annual Review of Pharmacology and Toxicology. 29: 441-74. PMID 2543273 DOI: 10.1146/annurev.pa.29.040189.002301  1
1989 Wroblewski JT, Fadda E, Mazzetta J, Lazarewicz JW, Costa E. Glycine and D-serine act as positive modulators of signal transduction at N-methyl-D-aspartate sensitive glutamate receptors in cultured cerebellar granule cells. Neuropharmacology. 28: 447-52. PMID 2542835 DOI: 10.1016/0028-3908(89)90077-4  1
1989 Danysz W, Wroblewski JT, Brooker G, Costa E. Modulation of glutamate receptors by phencyclidine and glycine in the rat cerebellum: cGMP increase in vivo. Brain Research. 479: 270-6. PMID 2538209 DOI: 10.1016/0006-8993(89)91628-4  1
1989 Lazarewicz JW, Wroblewski JT, Palmer ME, Costa E. Reduction of disulfide bonds activates NMDA-sensitive glutamate receptors in primary cultures of cerebellar granule cells Neuroscience Research Communications. 4: 91-97.  1
1989 Danysz W, Wroblewski JT. Amnesic properties of glutamate receptor antagonists Neuroscience Research Communications. 5: 9-18.  1
1988 Danysz W, Wroblewski JT, Costa E. Learning impairment in rats by N-methyl-D-aspartate receptor antagonists. Neuropharmacology. 27: 653-6. PMID 2901678 DOI: 10.1016/0028-3908(88)90189-X  1
1988 Fadda E, Danysz W, Wroblewski JT, Costa E. Glycine and D-serine increase the affinity of N-methyl-D-aspartate sensitive glutamate binding sites in rat brain synaptic membranes. Neuropharmacology. 27: 1183-5. PMID 2849731 DOI: 10.1016/0028-3908(88)90015-9  1
1988 Lazarewicz JW, Wroblewski JT, Palmer ME, Costa E. Activation of N-methyl-D-aspartate-sensitive glutamate receptors stimulates arachidonic acid release in primary cultures of cerebellar granule cells. Neuropharmacology. 27: 765-9. PMID 2843786 DOI: 10.1016/0028-3908(88)90088-3  1
1988 Nicoletti F, Wroblewski JT, Fadda E, Costa E. Pertussis toxin inhibits signal transduction at a specific metabolotropic glutamate receptor in primary cultures of cerebellar granule cells. Neuropharmacology. 27: 551-6. PMID 2843781 DOI: 10.1016/0028-3908(88)90174-8  1
1987 Wroblewski JT, Nicoletti F, Fadda E, Costa E. Phencyclidine is a negative allosteric modulator of signal transduction at two subclasses of excitatory amino acid receptors. Proceedings of the National Academy of Sciences of the United States of America. 84: 5068-72. PMID 3037532  1
1987 Nicoletti F, Wroblewski JT, Alho H, Eva C, Fadda E, Costa E. Lesions of putative glutamatergic pathways potentiate the increase of inositol phospholipid hydrolysis elicited by excitatory amino acids. Brain Research. 436: 103-12. PMID 2891413 DOI: 10.1016/0006-8993(87)91561-7  1
1987 Novelli A, Nicoletti F, Wroblewski JT, Alho H, Costa E, Guidotti A. Excitatory amino acid receptors coupled with guanylate cyclase in primary cultures of cerebellar granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 40-7. PMID 2879898  1
1987 Nicoletti F, Wroblewski JT, Costa E. Magnesium ions inhibit the stimulation of inositol phospholipid hydrolysis by endogenous excitatory amino acids in primary cultures of cerebellar granule cells. Journal of Neurochemistry. 48: 967-73. PMID 2879893 DOI: 10.1111/j.1471-4159.1987.tb05611.x  1
1986 Nicoletti F, Wroblewski JT, Iadarola MJ, Costa E. Serine-O-phosphate, an endogenous metabolite, inhibits the stimulation of inositol phospholipid hydrolysis elicited by ibotenic acid in rat hippocampal slices. Neuropharmacology. 25: 335-8. PMID 3084992 DOI: 10.1016/0028-3908(86)90262-5  1
1986 Nicoletti F, Wroblewski JT, Novelli A, Alho H, Guidotti A, Costa E. The activation of inositol phospholipid metabolism as a signal-transducing system for excitatory amino acids in primary cultures of cerebellar granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 1905-11. PMID 3016212  1
1986 Vicini S, Wroblewski JT, Costa E. Pharmacological modulation of GABAergic transmission in cultured cerebellar neurons. Neuropharmacology. 25: 207-11. PMID 3010162  1
1986 Nicoletti F, Wroblewski JT, Novelli A, Guidotti A, Costa E. Excitatory amino acid signal transduction in cerebellar cell cultures. Functional Neurology. 1: 345-9. PMID 2886406  1
1986 Nicoletti F, Iadarola MJ, Wroblewski JT, Costa E. Excitatory amino acid recognition sites coupled with inositol phospholipid metabolism: developmental changes and interaction with alpha 1-adrenoceptors. Proceedings of the National Academy of Sciences of the United States of America. 83: 1931-5. PMID 2869493  1
1985 Wroblewski JT, Blaker WD, Meek JL. Ornithine as a precursor of neurotransmitter glutamate: effect of canaline on ornithine aminotransferase activity and glutamate content in the septum of rat brain. Brain Research. 329: 161-8. PMID 2858253 DOI: 10.1016/0006-8993(85)90521-9  1
1985 Wroblewski JT, Nicoletti F, Costa E. Different coupling of excitatory amino acid receptors with Ca2+ channels in primary cultures of cerebellar granule cells. Neuropharmacology. 24: 919-21. PMID 2414684 DOI: 10.1016/0028-3908(85)90046-2  1
1984 Kataoka Y, Gutman Y, Guidotti A, Panula P, Wroblewski J, Cosenza-Murphy D, Wu JY, Costa E. Intrinsic GABAergic system of adrenal chromaffin cells. Proceedings of the National Academy of Sciences of the United States of America. 81: 3218-22. PMID 6328506  1
1978 DomaÅ„ska-Janik K, Bronieszewska-Ardelt B, Wróblewski JT. Effect of fatty acids on rat brain particulate hexokinase. Journal of Neurochemistry. 30: 1157-61. PMID 660192  1
1977 Wróblewski JT, Lazarewicz JW. The role of adenylate energy charge and divalent cations in the regulation of brain hexokinase activity. Bulletin De L'AcadéMie Polonaise Des Sciences. SéRie Des Sciences Biologiques. 25: 557-63. PMID 589500  1
1976 Wróblewski JT, DomaÅ„ska-Janik K. Effect of oleic acid on the activity of soluble hexokinase from guinea pig brain. Bulletin De L'AcadéMie Polonaise Des Sciences. SéRie Des Sciences Biologiques. 24: 423-8. PMID 8193  0.68
1975 Broniszewska-Ardelt B, Wróblewski JT. The activity of phosphofructokinase, pyruvate kinase and lactate dehydrogenase in guinea pig and rat brains in normal and hypoxic conditions. Bulletin De L'AcadéMie Polonaise Des Sciences. SéRie Des Sciences Biologiques. 23: 505-12. PMID 127651  0.68
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