Jarda T. Wroblewski - Publications

Affiliations: 
Georgetown 
Area:
Neuropharmacology, glutamate receptors
Website:
http://pharmacology.georgetown.edu/faculty/facwrobl.html

91 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Bowman Dalley C, Wroblewska B, Wolfe BB, Wroblewski JT. The Role of Metabotropic Glutamate Receptor 1 Dependent Signaling in Glioma Viability. The Journal of Pharmacology and Experimental Therapeutics. PMID 30054311 DOI: 10.1124/jpet.118.250159  0.533
2015 Gelb T, Pshenichkin S, Hathaway HA, Grajkowska E, Dalley CB, Wolfe BB, Wroblewski JT. Atypical signaling of metabotropic glutamate receptor 1 in human melanoma cells. Biochemical Pharmacology. 98: 182-9. PMID 26291396 DOI: 10.1016/J.Bcp.2015.08.091  0.869
2015 DiRaddo JO, Miller EJ, Bowman-Dalley C, Wroblewska B, Javidnia M, Grajkowska E, Wolfe BB, Liotta DC, Wroblewski JT. Chloride is an Agonist of Group II and III Metabotropic Glutamate Receptors. Molecular Pharmacology. 88: 450-9. PMID 26089372 DOI: 10.1124/Mol.114.096420  0.824
2015 Hathaway HA, Pshenichkin S, Grajkowska E, Gelb T, Emery AC, Wolfe BB, Wroblewski JT. Pharmacological characterization of mGlu1 receptors in cerebellar granule cells reveals biased agonism. Neuropharmacology. 93: 199-208. PMID 25700650 DOI: 10.1016/J.Neuropharm.2015.02.007  0.846
2015 Gelb T, Pshenichkin S, Rodriguez OC, Hathaway HA, Grajkowska E, DiRaddo JO, Wroblewska B, Yasuda RP, Albanese C, Wolfe BB, Wroblewski JT. Metabotropic glutamate receptor 1 acts as a dependence receptor creating a requirement for glutamate to sustain the viability and growth of human melanomas. Oncogene. 34: 2711-20. PMID 25065592 DOI: 10.1038/Onc.2014.231  0.836
2015 Gelb T, Pshenichkin S, Hathaway HA, Grajkowska E, Wolfe BB, Wroblewski JT. Abstract A15: mGlu1 Receptors and downstream signal transduction proteins as therapeutic targets for the treatment of metastatic melanoma Cancer Research. 75. DOI: 10.1158/1538-7445.Mel2014-A15  0.863
2014 Gelb T, Hathaway HA, Wroblewski JT. Triple threat treatment: Exploiting the dependence receptor properties of metabotropic glutamate receptor 1 against melanoma. Molecular & Cellular Oncology. 1: e969163. PMID 27308372 DOI: 10.4161/23723548.2014.969163  0.87
2014 DiRaddo JO, Miller EJ, Hathaway HA, Grajkowska E, Wroblewska B, Wolfe BB, Liotta DC, Wroblewski JT. A real-time method for measuring cAMP production modulated by Gαi/o-coupled metabotropic glutamate receptors. The Journal of Pharmacology and Experimental Therapeutics. 349: 373-82. PMID 24659805 DOI: 10.1124/Jpet.113.211532  0.82
2013 DiRaddo JO, Pshenichkin S, Gelb T, Wroblewski JT. Two newly identified exons in human GRM1 express a novel splice variant of metabotropic glutamate 1 receptor. Gene. 519: 367-73. PMID 23481697 DOI: 10.1016/J.Gene.2013.02.009  0.836
2012 Emery AC, DiRaddo JO, Miller E, Hathaway HA, Pshenichkin S, Takoudjou GR, Grajkowska E, Yasuda RP, Wolfe BB, Wroblewski JT. Ligand bias at metabotropic glutamate 1a receptors: molecular determinants that distinguish β-arrestin-mediated from G protein-mediated signaling. Molecular Pharmacology. 82: 291-301. PMID 22584219 DOI: 10.1124/Mol.112.078444  0.783
2011 Pshenichkin S, Surin A, Surina E, KlauziÅ„ska M, Grajkowska E, Luchenko V, DoliÅ„ska M, Wroblewska B, Wroblewski JT. Heat shock enhances CMV-IE promoter-driven metabotropic glutamate receptor expression and toxicity in transfected cells. Neuropharmacology. 60: 1292-300. PMID 21241715 DOI: 10.1016/j.neuropharm.2011.01.010  0.429
2011 Nicoletti F, Bockaert J, Collingridge GL, Conn PJ, Ferraguti F, Schoepp DD, Wroblewski JT, Pin JP. Metabotropic glutamate receptors: from the workbench to the bedside. Neuropharmacology. 60: 1017-41. PMID 21036182 DOI: 10.1016/J.Neuropharm.2010.10.022  0.641
2010 Emery AC, Pshenichkin S, Takoudjou GR, Grajkowska E, Wolfe BB, Wroblewski JT. The protective signaling of metabotropic glutamate receptor 1 Is mediated by sustained, beta-arrestin-1-dependent ERK phosphorylation. The Journal of Biological Chemistry. 285: 26041-8. PMID 20566651 DOI: 10.1074/jbc.M110.139899  0.822
2010 KOZIKOWSKI AP, STEENSMA D, VARASI M, PSHENICHKIN S, SURINA E, WROBLEWSKI JT. ChemInform Abstract: α-Substituted Quisqualic Acid Analogues: New Metabotropic Glutamate Receptor Group II Selective Antagonists. Cheminform. 29: no-no. DOI: 10.1002/CHIN.199824162  0.483
2010 MA D, TIAN H, SUN H, KOZIKOWSKI AP, PSHENICHKIN S, WROBLEWSKI JT. ChemInform Abstract: Synthesis and Biological Activity of Cyclic Analogues of MPPG and MCPG as Metabotropic Glutamate Receptor Antagonists. Cheminform. 28: no-no. DOI: 10.1002/CHIN.199740239  0.591
2008 Pshenichkin S, DoliÅ„ska M, KlauziÅ„ska M, Luchenko V, Grajkowska E, Wroblewski JT. Dual neurotoxic and neuroprotective role of metabotropic glutamate receptor 1 in conditions of trophic deprivation - possible role as a dependence receptor. Neuropharmacology. 55: 500-8. PMID 18619982 DOI: 10.1016/j.neuropharm.2008.06.039  0.608
2008 Wroblewska B, Ramadan E, Bacich DJ, O'Keefe DS, Heston WDW, Bukhari N, Wegorzewska I, Bzdega T, Wroblewski JT, Kozikowski A, Yamamoto T, Neale JH. Probing the functions of NAAG via NAAG peptidases and MGLUR3 Journal of Neurochemistry. 81: 69-70. DOI: 10.1046/J.1471-4159.2002.00052.X  0.388
2007 Surin A, Pshenichkin S, Grajkowska E, Surina E, Wroblewski JT. Cyclothiazide selectively inhibits mGluR1 receptors interacting with a common allosteric site for non-competitive antagonists. Neuropharmacology. 52: 744-54. PMID 17095021 DOI: 10.1016/j.neuropharm.2006.09.018  0.68
2006 Iso Y, Grajkowska E, Wroblewski JT, Davis J, Goeders NE, Johnson KM, Sanker S, Roth BL, Tueckmantel W, Kozikowski AP. Synthesis and structure-activity relationships of 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine analogues as potent, noncompetitive metabotropic glutamate receptor subtype 5 antagonists; search for cocaine medications. Journal of Medicinal Chemistry. 49: 1080-100. PMID 16451073 DOI: 10.1021/Jm050570F  0.479
2006 Makarewicz D, Gadamski R, Ziembowicz A, Kozikowski AP, Wroblewski JT, Lazarewicz JW. Neuroprotective effects of the agonist of metabotropic glutamate receptors ABHxD-I in two animal models of cerebral ischaemia. Resuscitation. 68: 119-26. PMID 16325990 DOI: 10.1016/J.Resuscitation.2005.05.018  0.651
2005 Alagille D, Baldwin RM, Roth BL, Wroblewski JT, Grajkowska E, Tamagnan GD. Synthesis and receptor assay of aromatic-ethynyl-aromatic derivatives with potent mGluR5 antagonist activity. Bioorganic & Medicinal Chemistry. 13: 197-209. PMID 15582465 DOI: 10.1016/j.bmc.2004.09.042  0.563
2004 Yamamoto T, Hirasawa S, Wroblewska B, Grajkowska E, Zhou J, Kozikowski A, Wroblewski J, Neale JH. Antinociceptive effects of N-acetylaspartylglutamate (NAAG) peptidase inhibitors ZJ-11, ZJ-17 and ZJ-43 in the rat formalin test and in the rat neuropathic pain model. The European Journal of Neuroscience. 20: 483-94. PMID 15233757 DOI: 10.1111/J.1460-9568.2004.03504.X  0.356
2004 Olszewski RT, Bukhari N, Zhou J, Kozikowski AP, Wroblewski JT, Shamimi-Noori S, Wroblewska B, Bzdega T, Vicini S, Barton FB, Neale JH. NAAG peptidase inhibition reduces locomotor activity and some stereotypes in the PCP model of schizophrenia via group II mGluR. Journal of Neurochemistry. 89: 876-85. PMID 15140187 DOI: 10.1111/J.1471-4159.2004.02358.X  0.51
2004 Kozikowski AP, Zhang J, Nan F, Petukhov PA, Grajkowska E, Wroblewski JT, Yamamoto T, Bzdega T, Wroblewska B, Neale JH. Synthesis of urea-based inhibitors as active site probes of glutamate carboxypeptidase II: efficacy as analgesic agents. Journal of Medicinal Chemistry. 47: 1729-38. PMID 15027864 DOI: 10.1021/Jm0306226  0.413
2003 Shi Q, Savage JE, Hufeisen SJ, Rauser L, Grajkowska E, Ernsberger P, Wroblewski JT, Nadeau JH, Roth BL. L-homocysteine sulfinic acid and other acidic homocysteine derivatives are potent and selective metabotropic glutamate receptor agonists. The Journal of Pharmacology and Experimental Therapeutics. 305: 131-42. PMID 12649361 DOI: 10.1124/Jpet.102.047092  0.586
2002 Rong SB, Zhang J, Neale JH, Wroblewski JT, Wang S, Kozikowski AP. Molecular modeling of the interactions of glutamate carboxypeptidase II with its potent NAAG-based inhibitors. Journal of Medicinal Chemistry. 45: 4140-52. PMID 12213057 DOI: 10.1021/Jm010561G  0.5
2001 Kozikowski AP, Nan F, Conti P, Zhang J, Ramadan E, Bzdega T, Wroblewska B, Neale JH, Pshenichkin S, Wroblewski JT. Design of remarkably simple, yet potent urea-based inhibitors of glutamate carboxypeptidase II (NAALADase). Journal of Medicinal Chemistry. 44: 298-301. PMID 11462970 DOI: 10.1021/Jm000406M  0.374
2001 Mukhopadhyaya JK, Kozikowski AP, Grajkowska E, Pshenichkin S, Wroblewski JT. Synthesis of N(1)-substituted analogues of (2R,4R)-4-amino-pyrrolidine-2,4-dicarboxylic acid as agonists, partial agonists, and antagonists of group II metabotropic glutamate receptors. Bioorganic & Medicinal Chemistry Letters. 11: 1919-24. PMID 11459661 DOI: 10.1016/S0960-894X(01)00329-8  0.433
2000 Nan F, Bzdega T, Pshenichkin S, Wroblewski JT, Wroblewska B, Neale JH, Kozikowski AP. Dual function glutamate-related ligands: discovery of a novel, potent inhibitor of glutamate carboxypeptidase II possessing mGluR3 agonist activity. Journal of Medicinal Chemistry. 43: 772-4. PMID 10715144 DOI: 10.1021/Jm9905559  0.529
1999 Kozikowski AP, Araldi GL, Tückmantel W, Pshenichkin S, Surina E, Wroblewski JT. 1-amino-APDC, a partial agonist of group II metabotropic glutamate receptors with neuroprotective properties. Bioorganic & Medicinal Chemistry Letters. 9: 1721-6. PMID 10397508 DOI: 10.1016/S0960-894X(99)00266-8  0.564
1998 Ma D, Ma Z, Kozikowski AP, Pshenichkin S, Wroblewski JT. Synthesis and biological evaluation of two analogues of (S)-alpha-methyl-3-carboxyphenylalanine. Bioorganic & Medicinal Chemistry Letters. 8: 2447-50. PMID 9873559 DOI: 10.1016/S0960-894X(98)00409-0  0.478
1998 Kozikowski AP, Steensma D, Varasi M, Pshenichkin S, Surina E, Wroblewski JT. alpha-substituted quisqualic acid analogs: new metabotropic glutamate receptor group II selective antagonists. Bioorganic & Medicinal Chemistry Letters. 8: 447-52. PMID 9871596 DOI: 10.1016/S0960-894X(98)00052-3  0.638
1998 Kozikowski AP, Araldi GL, Flippen-Anderson J, George C, Pshenichkin S, Surina E, Wroblewski J. Synthesis and metabotropic glutamate receptor activity of a 2- aminobicyclo[3.2.0]Heptane-2,5-dicarboxylic acid, a molecule possessing an extended glutamate conformation Bioorganic and Medicinal Chemistry Letters. 8: 925-930. PMID 9871513 DOI: 10.1016/S0960-894X(98)00146-2  0.594
1998 Xiao Y, Meyer EL, Thompson JM, Surin A, Wroblewski J, Kellar KJ. Rat alpha3/beta4 subtype of neuronal nicotinic acetylcholine receptor stably expressed in a transfected cell line: pharmacology of ligand binding and function. Molecular Pharmacology. 54: 322-33. PMID 9687574 DOI: 10.1124/Mol.54.2.322  0.409
1998 Bruno V, Wroblewska B, Wroblewski JT, Fiore L, Nicoletti F. Neuroprotective activity of N-acetylaspartylglutamate in cultured cortical cells. Neuroscience. 85: 751-7. PMID 9639269 DOI: 10.1016/S0306-4522(97)00531-9  0.534
1998 Kozikowski AP, Steensma D, Araldi GL, Tückmantel W, Wang S, Pshenichkin S, Surina E, Wroblewski JT. Synthesis and biology of the conformationally restricted ACPD analogue, 2-aminobicyclo[2.1.1]hexane-2,5-dicarboxylic acid-I, a potent mGluR agonist. Journal of Medicinal Chemistry. 41: 1641-50. PMID 9572889 DOI: 10.1021/Jm970719Q  0.558
1997 Wroblewska B, Wroblewski JT, Pshenichkin S, Surin A, Sullivan SE, Neale JH. N-acetylaspartylglutamate selectively activates mGluR3 receptors in transfected cells. Journal of Neurochemistry. 69: 174-81. PMID 9202308 DOI: 10.1046/J.1471-4159.1997.69010174.X  0.663
1997 Ma D, Tian H, Sun H, Kozikowski AP, Pshenichkin S, Wroblewski JT. Synthesis and biological activity of cyclic analogues of MPPG and MCPG as metabotropic glutamate receptor antagonists Bioorganic and Medicinal Chemistry Letters. 7: 1195-1198. DOI: 10.1016/S0960-894X(97)00177-7  0.547
1997 Tückmantel W, Kozikowski AP, Wang S, Pshenichkin S, Wroblewski JT. Synthesis, molecular modeling, and biology of the 1-benzyl derivative of APDC - an apparent mGluR6 selective ligand Bioorganic and Medicinal Chemistry Letters. 7: 601-606. DOI: 10.1016/S0960-894X(97)00068-1  0.444
1996 Danysz W, Raulli R, Wroblewski JT. Concanavalin A enhances quisqualate-induced calcium influx in cerebellar granule cells in culture. Acta Neurobiologiae Experimentalis. 56: 649-56. PMID 8917894  0.482
1996 Kozikowski AP, Liao Y, Tückmantel W, Wang S, Pshenichkin S, Surin A, Thomsen C, Wroblewski JT. Synthesis and biology of the rigidified glutamate analogue, trans-2-carboxyazetidine-3-acetic acid (t-CAA) Bioorganic and Medicinal Chemistry Letters. 6: 2559-2564. DOI: 10.1016/0960-894X(96)00464-7  0.458
1996 Wroblewska B, Surin A, Pshenichkin S, Wroblewski J, Neale J. N-acetylaspartylglutamate (NAAG) as a selective agonist of mGluR3 Neuropharmacology. 35: A34. DOI: 10.1016/0028-3908(96)84783-6  0.346
1996 Wroblewski J, Pshenichkin S, Surina E, Surin A. Modulation of metabotropic glutamate receptors by cyclothiazide Neuropharmacology. 35: A34. DOI: 10.1016/0028-3908(96)84782-4  0.676
1995 Danysz W, Wroblewski JT. Concanavalin A increases N-methyl-D-aspartate-induced Ca2+ influx in cerebellar granule cells in culture. Polish Journal of Pharmacology. 47: 31-6. PMID 7550546  0.45
1994 Costa E, Armstrong DM, Guidotti A, Kharlamov A, Kiedrowski L, Manev H, Polo A, Wroblewski JT. Gangliosides in the protection against glutamate excitotoxicity. Progress in Brain Research. 101: 357-73. PMID 8029464 DOI: 10.1016/S0079-6123(08)61962-7  0.661
1994 Raulli R, Alho H, Wroblewski JT. N-methyl-D-aspartate receptor-induced translocation of protein kinase C to the nucleus in rat cerebellar slices. Neurochemistry International. 24: 209-14. PMID 8025529 DOI: 10.1016/0197-0186(94)90077-9  0.402
1994 Santi MR, Ikonomovic S, Wroblewski JT, Grayson DR. Temporal and depolarization-induced changes in the absolute amounts of mRNAs encoding metabotropic glutamate receptors in cerebellar granule neurons in vitro. Journal of Neurochemistry. 63: 1207-17. PMID 7931274 DOI: 10.1046/J.1471-4159.1994.63041207.X  0.483
1994 Paulsen RE, Raulli R, Grayson DR, Wroblewski JT. Acute and long-term inhibition of agonist-stimulated phosphoinositide hydrolysis by pulse treatment of cerebellar granule cells with TPA. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 22: 67-79. PMID 7916769 DOI: 10.1007/BF03160095  0.379
1994 Kiedrowski L, Wroblewski JT, Costa E. Intracellular sodium concentration in cultured cerebellar granule cells challenged with glutamate. Molecular Pharmacology. 45: 1050-4. PMID 7910657  0.309
1994 Kiedrowski L, Brooker G, Costa E, Wroblewski JT. Glutamate impairs neuronal calcium extrusion while reducing sodium gradient. Neuron. 12: 295-300. PMID 7906528 DOI: 10.1016/0896-6273(94)90272-0  0.553
1993 Kozikowski AP, Tückmantel W, Liao Y, Manev H, Ikonomovic S, Wroblewski JT. Synthesis and metabotropic receptor activity of the novel rigidified glutamate analogues (+)- and (-)-trans-azetidine-2,4-dicarboxylic acid and their N-methyl derivatives. Journal of Medicinal Chemistry. 36: 2706-8. PMID 8410984 DOI: 10.1021/Jm00070A016  0.561
1993 Costa E, Armstrong D, Guidotti A, Kharlamov A, Kiedrowski L, Wroblewski JT. Ganglioside GM1 and its semisynthetic lysogangliosides reduce glutamate neurotoxicity by a novel mechanism. Advances in Experimental Medicine and Biology. 341: 129-41. PMID 7906915 DOI: 10.1007/978-1-4615-2484-7_12  0.641
1993 Sweetnam PM, Saab OH, Wroblewski JT, Price CH, Karbon EW, Ferkany JW. The envelope glycoprotein of HIV-1 alters NMDA receptor function. The European Journal of Neuroscience. 5: 276-83. PMID 7726990  0.428
1993 Wroblewska B, Wroblewski JT, Saab OH, Neale JH. N-acetylaspartylglutamate inhibits forskolin-stimulated cyclic AMP levels via a metabotropic glutamate receptor in cultured cerebellar granule cells. Journal of Neurochemistry. 61: 943-8. PMID 7689644 DOI: 10.1111/J.1471-4159.1993.Tb03606.X  0.616
1992 Lazarewicz JW, Salinska E, Wroblewski JT. NMDA receptor-mediated arachidonic acid release in neurons: role in signal transduction and pathological aspects. Advances in Experimental Medicine and Biology. 318: 73-89. PMID 1386178  0.767
1992 Kiedrowski L, Costa E, Wroblewski JT. In vitro interaction between cerebellar astrocytes and granule cells: a putative role for nitric oxide. Neuroscience Letters. 135: 59-61. PMID 1371859 DOI: 10.1016/0304-3940(92)90135-T  0.688
1992 Kiedrowski L, Costa E, Wroblewski JT. Glutamate receptor agonists stimulate nitric oxide synthase in primary cultures of cerebellar granule cells. Journal of Neurochemistry. 58: 335-41. PMID 1370078 DOI: 10.1111/J.1471-4159.1992.Tb09315.X  0.702
1992 Kiedrowski L, Costa E, Wroblewski JT. Sodium nitroprusside inhibits N-methyl-D-aspartate-evoked calcium influx via a nitric oxide- and cGMP-independent mechanism. Molecular Pharmacology. 41: 779-84. PMID 1314946  0.411
1991 Kiedrowski L, Manev H, Costa E, Wroblewski JT. Inhibition of glutamate-induced cell death by sodium nitroprusside is not mediated by nitric oxide. Neuropharmacology. 30: 1241-3. PMID 1685560 DOI: 10.1016/0028-3908(91)90171-7  0.599
1991 Raulli R, Danysz W, Wroblewski JT. Pretreatment of cerebellar granule cells with concanavalin A potentiates quisqualate-stimulated phosphoinositide hydrolysis. Journal of Neurochemistry. 56: 2116-24. PMID 1674000 DOI: 10.1111/j.1471-4159.1991.tb03474.x  0.539
1991 Raulli R, Wroblewski JT. Stimulation of phosphoinositide hydrolysis by ibotenic acid in cerebellar neurons via two glutamate receptor subtypes Drug Development Research. 24: 375-384. DOI: 10.1002/Ddr.430240408  0.71
1990 Lazarewicz JW, Wroblewski JT, Costa E. N-methyl-D-aspartate-sensitive glutamate receptors induce calcium-mediated arachidonic acid release in primary cultures of cerebellar granule cells. Journal of Neurochemistry. 55: 1875-81. PMID 2172463 DOI: 10.1111/J.1471-4159.1990.Tb05771.X  0.832
1990 Manev H, Costa E, Wroblewski JT, Guidotti A. Abusive stimulation of excitatory amino acid receptors: a strategy to limit neurotoxicity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 4: 2789-97. PMID 2165013 DOI: 10.1096/Fasebj.4.10.2165013  0.766
1990 Kozikowski AP, Tückmantel W, Reynolds IJ, Wroblewski JT. Synthesis and bioactivity of a new class of rigid glutamate analogues. Modulators of the N-methyl-D-aspartate receptor. Journal of Medicinal Chemistry. 33: 1561-71. PMID 2160533 DOI: 10.1021/Jm00168A007  0.565
1990 Danysz W, Fadda E, Wroblewski JT, Costa E. [3H]D-serine labels strychnine-insensitive glycine recognition sites of rat central nervous system. Life Sciences. 46: 155-64. PMID 2154648 DOI: 10.1016/0024-3205(90)90100-6  0.607
1989 Hynie S, Wroblewski JT, Costa E. Profile of phosphatidylinositol metabolism stimulated by carbachol and glutamate in primary cultures of rat cerebellar neurons. Neuropharmacology. 28: 1309-15. PMID 2615914 DOI: 10.1016/0028-3908(89)90004-X  0.571
1989 Danysz W, Fadda E, Wroblewski JT, Costa E. Different modes of action of 3-amino-1-hydroxy-2-pyrrolidone (HA-966) and 7-chlorokynurenic acid in the modulation of N-methyl-D-aspartate-sensitive glutamate receptors. Molecular Pharmacology. 36: 912-6. PMID 2574820  0.533
1989 Danysz W, Fadda E, Wroblewski JT, Costa E. Kynurenate and 2-amino-5-phosphonovalerate interact with multiple binding sites of the N-methyl-D-aspartate-sensitive glutamate receptor domain. Neuroscience Letters. 96: 340-4. PMID 2566140 DOI: 10.1016/0304-3940(89)90402-3  0.673
1989 Wroblewski JT, Danysz W. Modulation of glutamate receptors: molecular mechanisms and functional implications. Annual Review of Pharmacology and Toxicology. 29: 441-74. PMID 2543273 DOI: 10.1146/annurev.pa.29.040189.002301  0.713
1989 Wroblewski JT, Fadda E, Mazzetta J, Lazarewicz JW, Costa E. Glycine and D-serine act as positive modulators of signal transduction at N-methyl-D-aspartate sensitive glutamate receptors in cultured cerebellar granule cells. Neuropharmacology. 28: 447-52. PMID 2542835 DOI: 10.1016/0028-3908(89)90077-4  0.802
1989 Danysz W, Wroblewski JT, Brooker G, Costa E. Modulation of glutamate receptors by phencyclidine and glycine in the rat cerebellum: cGMP increase in vivo. Brain Research. 479: 270-6. PMID 2538209 DOI: 10.1016/0006-8993(89)91628-4  0.737
1989 Lazarewicz JW, Wroblewski JT, Palmer ME, Costa E. Reduction of disulfide bonds activates NMDA-sensitive glutamate receptors in primary cultures of cerebellar granule cells Neuroscience Research Communications. 4: 91-97.  0.731
1989 Danysz W, Wroblewski JT. Amnesic properties of glutamate receptor antagonists Neuroscience Research Communications. 5: 9-18.  0.63
1988 Danysz W, Wroblewski JT, Costa E. Learning impairment in rats by N-methyl-D-aspartate receptor antagonists. Neuropharmacology. 27: 653-6. PMID 2901678 DOI: 10.1016/0028-3908(88)90189-X  0.623
1988 Fadda E, Danysz W, Wroblewski JT, Costa E. Glycine and D-serine increase the affinity of N-methyl-D-aspartate sensitive glutamate binding sites in rat brain synaptic membranes. Neuropharmacology. 27: 1183-5. PMID 2849731 DOI: 10.1016/0028-3908(88)90015-9  0.661
1988 Lazarewicz JW, Wroblewski JT, Palmer ME, Costa E. Activation of N-methyl-D-aspartate-sensitive glutamate receptors stimulates arachidonic acid release in primary cultures of cerebellar granule cells. Neuropharmacology. 27: 765-9. PMID 2843786 DOI: 10.1016/0028-3908(88)90088-3  0.824
1988 Nicoletti F, Wroblewski JT, Fadda E, Costa E. Pertussis toxin inhibits signal transduction at a specific metabolotropic glutamate receptor in primary cultures of cerebellar granule cells. Neuropharmacology. 27: 551-6. PMID 2843781 DOI: 10.1016/0028-3908(88)90174-8  0.757
1987 Wroblewski JT, Nicoletti F, Fadda E, Costa E. Phencyclidine is a negative allosteric modulator of signal transduction at two subclasses of excitatory amino acid receptors. Proceedings of the National Academy of Sciences of the United States of America. 84: 5068-72. PMID 3037532 DOI: 10.1073/Pnas.84.14.5068  0.756
1987 Nicoletti F, Wroblewski JT, Alho H, Eva C, Fadda E, Costa E. Lesions of putative glutamatergic pathways potentiate the increase of inositol phospholipid hydrolysis elicited by excitatory amino acids. Brain Research. 436: 103-12. PMID 2891413 DOI: 10.1016/0006-8993(87)91561-7  0.594
1987 Novelli A, Nicoletti F, Wroblewski JT, Alho H, Costa E, Guidotti A. Excitatory amino acid receptors coupled with guanylate cyclase in primary cultures of cerebellar granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 40-7. PMID 2879898 DOI: 10.1523/Jneurosci.07-01-00040.1987  0.5
1987 Nicoletti F, Wroblewski JT, Costa E. Magnesium ions inhibit the stimulation of inositol phospholipid hydrolysis by endogenous excitatory amino acids in primary cultures of cerebellar granule cells. Journal of Neurochemistry. 48: 967-73. PMID 2879893 DOI: 10.1111/J.1471-4159.1987.Tb05611.X  0.659
1987 Novelli A, Nicoletti F, Wroblewski J, Alho H, Costa E, Guidotti A. Excitatory amino acid receptors coupled with guanylate cyclase in primary cultures of cerebellar granule cells The Journal of Neuroscience. 7: 40-47. DOI: 10.1523/JNEUROSCI.07-01-00040.1987  0.641
1986 Nicoletti F, Wroblewski JT, Iadarola MJ, Costa E. Serine-O-phosphate, an endogenous metabolite, inhibits the stimulation of inositol phospholipid hydrolysis elicited by ibotenic acid in rat hippocampal slices. Neuropharmacology. 25: 335-8. PMID 3084992 DOI: 10.1016/0028-3908(86)90262-5  0.524
1986 Nicoletti F, Wroblewski JT, Novelli A, Alho H, Guidotti A, Costa E. The activation of inositol phospholipid metabolism as a signal-transducing system for excitatory amino acids in primary cultures of cerebellar granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 1905-11. PMID 3016212  0.315
1986 Vicini S, Wroblewski JT, Costa E. Pharmacological modulation of GABAergic transmission in cultured cerebellar neurons. Neuropharmacology. 25: 207-11. PMID 3010162 DOI: 10.1016/0028-3908(86)90043-2  0.554
1986 Nicoletti F, Wroblewski JT, Novelli A, Guidotti A, Costa E. Excitatory amino acid signal transduction in cerebellar cell cultures. Functional Neurology. 1: 345-9. PMID 2886406  0.378
1986 Nicoletti F, Iadarola MJ, Wroblewski JT, Costa E. Excitatory amino acid recognition sites coupled with inositol phospholipid metabolism: developmental changes and interaction with alpha 1-adrenoceptors. Proceedings of the National Academy of Sciences of the United States of America. 83: 1931-5. PMID 2869493 DOI: 10.1073/Pnas.83.6.1931  0.601
1986 Nicoletti F, Wroblewski J, Novelli A, Alho H, Guidotti A, Costa E. The activation of inositol phospholipid metabolism as a signal- transducing system for excitatory amino acids in primary cultures of cerebellar granule cells The Journal of Neuroscience. 6: 1905-1911. DOI: 10.1523/Jneurosci.06-07-01905.1986  0.601
1985 Wroblewski JT, Blaker WD, Meek JL. Ornithine as a precursor of neurotransmitter glutamate: effect of canaline on ornithine aminotransferase activity and glutamate content in the septum of rat brain. Brain Research. 329: 161-8. PMID 2858253 DOI: 10.1016/0006-8993(85)90521-9  0.468
1985 Wroblewski JT, Nicoletti F, Costa E. Different coupling of excitatory amino acid receptors with Ca2+ channels in primary cultures of cerebellar granule cells. Neuropharmacology. 24: 919-21. PMID 2414684 DOI: 10.1016/0028-3908(85)90046-2  0.682
1984 Kataoka Y, Gutman Y, Guidotti A, Panula P, Wroblewski J, Cosenza-Murphy D, Wu JY, Costa E. Intrinsic GABAergic system of adrenal chromaffin cells. Proceedings of the National Academy of Sciences of the United States of America. 81: 3218-22. PMID 6328506 DOI: 10.1073/Pnas.81.10.3218  0.603
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